<?xml version="1.0" encoding="UTF-8"?><sbml xmlns="http://www.sbml.org/sbml/level2" level="2" version="1">  <model id="HumanRecon1">    <listOfUnitDefinitions>      <unitDefinition id="mmol_per_gDW_per_hr">        <listOfUnits>          <unit kind="mole" exponent="1" scale="-3" multiplier="1" offset="0"/>          <unit kind="gram" exponent="-1" scale="0" multiplier="1" offset="0"/>          <unit kind="second" exponent="-1" scale="0" multiplier="0.000277777777777778" offset="0"/>        </listOfUnits>      </unitDefinition>    </listOfUnitDefinitions>    <listOfCompartments>      <compartment id="c" name="Cytoplasm" spatialDimensions="3" constant="false"/>      <compartment id="e" name="Extracellular" spatialDimensions="3" constant="false"/>      <compartment id="l" name="Lysosome" spatialDimensions="3" constant="false"/>      <compartment id="m" name="Mitochondrion" spatialDimensions="3" constant="false"/>      <compartment id="n" name="Nucleus" spatialDimensions="3" constant="false"/>      <compartment id="r" name="Endoplasmic_reticulum" spatialDimensions="3" constant="false"/>      <compartment id="x" name="Peroxisome" spatialDimensions="3" constant="false"/>    </listOfCompartments>    <listOfSpecies>      <species id="M_10fthf5glu_c" name="10-formyltetrahydrofolate-[Glu](5)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C40H45N11O19</p>          </body>        </notes>      </species>      <species id="M_10fthf5glu_e" name="10-formyltetrahydrofolate-[Glu](5)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C40H45N11O19</p>          </body>        </notes>      </species>      <species id="M_10fthf5glu_l" name="10-formyltetrahydrofolate-[Glu](5)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C40H45N11O19</p>          </body>        </notes>      </species>      <species id="M_10fthf6glu_c" name="10-formyltetrahydrofolate-[Glu](6)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H51N12O22</p>          </body>        </notes>      </species>      <species id="M_10fthf6glu_e" name="10-formyltetrahydrofolate-[Glu](6)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H51N12O22</p>          </body>        </notes>      </species>      <species id="M_10fthf6glu_l" name="10-formyltetrahydrofolate-[Glu](6)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H51N12O22</p>          </body>        </notes>      </species>      <species id="M_10fthf7glu_c" name="10-formyltetrahydrofolate-[Glu](7)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C50H57N13O25</p>          </body>        </notes>      </species>      <species id="M_10fthf7glu_e" name="10-formyltetrahydrofolate-[Glu](7)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C50H57N13O25</p>          </body>        </notes>      </species>      <species id="M_10fthf7glu_l" name="10-formyltetrahydrofolate-[Glu](7)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C50H57N13O25</p>          </body>        </notes>      </species>      <species id="M_10fthf_c" name="10-Formyltetrahydrofolate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H21N7O7</p>          </body>        </notes>      </species>      <species id="M_10fthf_e" name="10-Formyltetrahydrofolate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H21N7O7</p>          </body>        </notes>      </species>      <species id="M_10fthf_l" name="10-Formyltetrahydrofolate" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H21N7O7</p>          </body>        </notes>      </species>      <species id="M_10fthf_m" name="10-Formyltetrahydrofolate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H21N7O7</p>          </body>        </notes>      </species>      <species id="M_12ppd_DASH_DASH_DASH_R_c" name="(R)-Propane-1,2-diol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H8O2</p>          </body>        </notes>      </species>      <species id="M_12ppd_DASH_DASH_DASH_S_c" name="(S)-Propane-1,2-diol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H8O2</p>          </body>        </notes>      </species>      <species id="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retn_c" name="13-cis-retinoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H27O2</p>          </body>        </notes>      </species>      <species id="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retn_r" name="13-cis-retinoate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H27O2</p>          </body>        </notes>      </species>      <species id="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retnglc_c" name="13-cis-retinoyl glucuronide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H35O8</p>          </body>        </notes>      </species>      <species id="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retnglc_e" name="13-cis-retinoyl glucuronide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H35O8</p>          </body>        </notes>      </species>      <species id="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retnglc_r" name="13-cis-retinoyl glucuronide" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H35O8</p>          </body>        </notes>      </species>      <species id="M_13dampp_c" name="1,3-Diaminopropane" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H12N2</p>          </body>        </notes>      </species>      <species id="M_13dpg_c" name="3-Phospho-D-glyceroyl phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H4O10P2</p>          </body>        </notes>      </species>      <species id="M_1mncam_c" name="1-Methylnicotinamide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H9N2O</p>          </body>        </notes>      </species>      <species id="M_1mncam_e" name="1-Methylnicotinamide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H9N2O</p>          </body>        </notes>      </species>      <species id="M_1p3h5c_m" name="L-1-Pyrroline-3-hydroxy-5-carboxylate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H6NO3</p>          </body>        </notes>      </species>      <species id="M_1pipdn2c_x" name="delta1-Piperideine-2-carboxylate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9NO2</p>          </body>        </notes>      </species>      <species id="M_1pyr5c_c" name="1-Pyrroline-5-carboxylate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H6NO2</p>          </body>        </notes>      </species>      <species id="M_1pyr5c_m" name="1-Pyrroline-5-carboxylate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H6NO2</p>          </body>        </notes>      </species>      <species id="M_23dpg_c" name="2,3-Disphospho-D-glycerate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H3O10P2</p>          </body>        </notes>      </species>      <species id="M_24nph_c" name="2,4 dihydroxy nitrophenol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H5NO4</p>          </body>        </notes>      </species>      <species id="M_24nph_e" name="2,4 dihydroxy nitrophenol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H5NO4</p>          </body>        </notes>      </species>      <species id="M_25aics_c" name="(S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C13H15N4O12P</p>          </body>        </notes>      </species>      <species id="M_25hvitd3_c" name="25-Hydroxyvitamin D3" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O2</p>          </body>        </notes>      </species>      <species id="M_25hvitd3_e" name="25-Hydroxyvitamin D3" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O2</p>          </body>        </notes>      </species>      <species id="M_25hvitd3_m" name="25-Hydroxyvitamin D3" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O2</p>          </body>        </notes>      </species>      <species id="M_2amac_c" name="2-Aminoacrylate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5NO2</p>          </body>        </notes>      </species>      <species id="M_2aobut_m" name="L-2-Amino-3-oxobutanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7NO3</p>          </body>        </notes>      </species>      <species id="M_2dr1p_c" name="2-Deoxy-D-ribose 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9O7P</p>          </body>        </notes>      </species>      <species id="M_2dr5p_c" name="2-Deoxy-D-ribose 5-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9O7P</p>          </body>        </notes>      </species>      <species id="M_2hb_c" name="2-Hydroxybutyrate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7O3</p>          </body>        </notes>      </species>      <species id="M_2hb_e" name="2-Hydroxybutyrate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7O3</p>          </body>        </notes>      </species>      <species id="M_2kmb_c" name="2-keto-4-methylthiobutyrate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H7O3S</p>          </body>        </notes>      </species>      <species id="M_2maacoa_m" name="2-Methyl-3-acetoacetyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H38N7O18P3S</p>          </body>        </notes>      </species>      <species id="M_2mb2coa_m" name="trans-2-Methylbut-2-enoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H38N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_2mbcoa_m" name="2-Methylbutanoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H40N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_2mcit_c" name="2-Methylcitrate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H7O7</p>          </body>        </notes>      </species>      <species id="M_2mcit_e" name="2-Methylcitrate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H7O7</p>          </body>        </notes>      </species>      <species id="M_2mop_m" name="2-Methyl-3-oxopropanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H5O3</p>          </body>        </notes>      </species>      <species id="M_2mp2coa_m" name="2-Methylprop-2-enoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H36N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_2obut_c" name="2-Oxobutanoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H5O3</p>          </body>        </notes>      </species>      <species id="M_2oxoadp_c" name="2-Oxoadipate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H6O5</p>          </body>        </notes>      </species>      <species id="M_2oxoadp_m" name="2-Oxoadipate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H6O5</p>          </body>        </notes>      </species>      <species id="M_2pg_c" name="D-Glycerate 2-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H4O7P</p>          </body>        </notes>      </species>      <species id="M_34dhmald_c" name="3,4-Dihydroxymandelaldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H8O4</p>          </body>        </notes>      </species>      <species id="M_34dhoxpeg_c" name="3,4-Dihydroxyphenylethyleneglycol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H10O4</p>          </body>        </notes>      </species>      <species id="M_34dhoxpeg_e" name="3,4-Dihydroxyphenylethyleneglycol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H10O4</p>          </body>        </notes>      </species>      <species id="M_34dhphe_c" name="3,4-Dihydroxy-L-phenylalanine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11NO4</p>          </body>        </notes>      </species>      <species id="M_34dhphe_e" name="3,4-Dihydroxy-L-phenylalanine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11NO4</p>          </body>        </notes>      </species>      <species id="M_34hpp_c" name="3-(4-Hydroxyphenyl)pyruvate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H7O4</p>          </body>        </notes>      </species>      <species id="M_35cgmp_c" name="3&apos;,5&apos;-Cyclic GMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N5O7P</p>          </body>        </notes>      </species>      <species id="M_3aib_DASH_DASH_DASH_D_c" name="D-3-Amino-isobutanoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2</p>          </body>        </notes>      </species>      <species id="M_3aib_DASH_DASH_DASH_D_e" name="D-3-Amino-isobutanoate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2</p>          </body>        </notes>      </species>      <species id="M_3aib_c" name="L-3-Amino-isobutanoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2</p>          </body>        </notes>      </species>      <species id="M_3aib_e" name="L-3-Amino-isobutanoate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2</p>          </body>        </notes>      </species>      <species id="M_3aib_m" name="L-3-Amino-isobutanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2</p>          </body>        </notes>      </species>      <species id="M_3dhguln_c" name="3-Dehydro-L-gulonate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O7</p>          </body>        </notes>      </species>      <species id="M_3dsphgn_c" name="3-Dehydrosphinganine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H38NO2</p>          </body>        </notes>      </species>      <species id="M_3hanthrn_c" name="3-Hydroxyanthranilate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H7NO3</p>          </body>        </notes>      </species>      <species id="M_3hbcoa_m" name="(S)-3-Hydroxybutanoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H38N7O18P3S</p>          </body>        </notes>      </species>      <species id="M_3hibutcoa_m" name="(S)-3-Hydroxyisobutyryl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H38N7O18P3S</p>          </body>        </notes>      </species>      <species id="M_3hmbcoa_m" name="(S)-3-Hydroxy-2-methylbutyryl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H40N7O18P3S</p>          </body>        </notes>      </species>      <species id="M_3hmp_m" name="3-Hydroxy-2-methylpropanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7O3</p>          </body>        </notes>      </species>      <species id="M_3mb2coa_m" name="3-Methylbut-2-enoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H38N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_3mgcoa_m" name="3-Methylglutaconyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H37N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_3mlda_c" name="3-Methylimidazoleacetic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H7N2O2</p>          </body>        </notes>      </species>      <species id="M_3mlda_e" name="3-Methylimidazoleacetic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H7N2O2</p>          </body>        </notes>      </species>      <species id="M_3mldz_c" name="3-Methylimidazole acetaldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H8N2O</p>          </body>        </notes>      </species>      <species id="M_3mob_m" name="3-Methyl-2-oxobutanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H7O3</p>          </body>        </notes>      </species>      <species id="M_3mop_m" name="(S)-3-Methyl-2-oxopentanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O3</p>          </body>        </notes>      </species>      <species id="M_3pg_c" name="3-Phospho-D-glycerate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H4O7P</p>          </body>        </notes>      </species>      <species id="M_3php_c" name="3-Phosphohydroxypyruvate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H2O7P</p>          </body>        </notes>      </species>      <species id="M_3sala_c" name="3-Sulfino-L-alanine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5NO4S</p>          </body>        </notes>      </species>      <species id="M_3sala_m" name="3-Sulfino-L-alanine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5NO4S</p>          </body>        </notes>      </species>      <species id="M_3snpyr_c" name="3-Sulfinopyruvate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H2O5S</p>          </body>        </notes>      </species>      <species id="M_3snpyr_m" name="3-Sulfinopyruvate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H2O5S</p>          </body>        </notes>      </species>      <species id="M_3spyr_c" name="3-Sulfopyruvate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H2O6S</p>          </body>        </notes>      </species>      <species id="M_3uib_c" name="3-Ureidoisobutyrate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9N2O3</p>          </body>        </notes>      </species>      <species id="M_44mctr_r" name="4,4-dimethylcholesta-8,14,24-trienol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H46O</p>          </body>        </notes>      </species>      <species id="M_44mzym_r" name="4,4-dimethylzymosterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H48O</p>          </body>        </notes>      </species>      <species id="M_4abut_c" name="4-Aminobutanoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2</p>          </body>        </notes>      </species>      <species id="M_4abut_e" name="4-Aminobutanoate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2</p>          </body>        </notes>      </species>      <species id="M_4abut_m" name="4-Aminobutanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2</p>          </body>        </notes>      </species>      <species id="M_4abutn_c" name="4-Aminobutanal" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H10NO</p>          </body>        </notes>      </species>      <species id="M_4fumacac_c" name="4-Fumarylacetoacetate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H6O6</p>          </body>        </notes>      </species>      <species id="M_4hdebrisoquine_c" name="4 hydroxy debrisoquine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H14N3O</p>          </body>        </notes>      </species>      <species id="M_4hdebrisoquine_e" name="4 hydroxy debrisoquine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H14N3O</p>          </body>        </notes>      </species>      <species id="M_4hglusa_m" name="L-4-Hydroxyglutamate semialdehyde" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9NO4</p>          </body>        </notes>      </species>      <species id="M_4hoxpacd_c" name="4-Hydroxyphenylacetaldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H8O2</p>          </body>        </notes>      </species>      <species id="M_4hphac_c" name="4-Hydroxyphenylacetate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H7O3</p>          </body>        </notes>      </species>      <species id="M_4hphac_e" name="4-Hydroxyphenylacetate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H7O3</p>          </body>        </notes>      </species>      <species id="M_4izp_c" name="4-Imidazolone-5-propanoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H7N2O3</p>          </body>        </notes>      </species>      <species id="M_4mlacac_c" name="4-Maleylacetoacetate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H6O6</p>          </body>        </notes>      </species>      <species id="M_4mop_m" name="4-Methyl-2-oxopentanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O3</p>          </body>        </notes>      </species>      <species id="M_4mtolbutamide_c" name="4 hydroxy tolbutamide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H18N2O4S</p>          </body>        </notes>      </species>      <species id="M_4mtolbutamide_e" name="4 hydroxy tolbutamide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H18N2O4S</p>          </body>        </notes>      </species>      <species id="M_4mzym_DASH_int1_r" name="4-Methylzymosterol intermediate 1" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H46O3</p>          </body>        </notes>      </species>      <species id="M_4mzym_DASH_int2_r" name="4-Methylzymosterol intermediate 2" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C28H44O</p>          </body>        </notes>      </species>      <species id="M_4nph_c" name="4-Nitrophenol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H5NO3</p>          </body>        </notes>      </species>      <species id="M_4nph_e" name="4-Nitrophenol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H5NO3</p>          </body>        </notes>      </species>      <species id="M_4nphsf_c" name="4-Nitrophenyl sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H4NO6S</p>          </body>        </notes>      </species>      <species id="M_4nphsf_e" name="4-Nitrophenyl sulfate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H4NO6S</p>          </body>        </notes>      </species>      <species id="M_4ppan_c" name="D-4&apos;-Phosphopantothenate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H15NO8P</p>          </body>        </notes>      </species>      <species id="M_4ppcys_c" name="N-((R)-4-Phosphopantothenoyl)-L-cysteine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H20N2O9PS</p>          </body>        </notes>      </species>      <species id="M_4pyrdx_c" name="4-Pyridoxate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H9NO4</p>          </body>        </notes>      </species>      <species id="M_4pyrdx_e" name="4-Pyridoxate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H9NO4</p>          </body>        </notes>      </species>      <species id="M_56dthm_c" name="5,6-Dihydrothymine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H8N2O2</p>          </body>        </notes>      </species>      <species id="M_56dura_c" name="5,6-dihydrouracil" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H6N2O2</p>          </body>        </notes>      </species>      <species id="M_5HPET_c" name="5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H31O4</p>          </body>        </notes>      </species>      <species id="M_5adtststerone_c" name="5alpha-Dihydrotestosterone" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H30O2</p>          </body>        </notes>      </species>      <species id="M_5adtststerone_e" name="5alpha-Dihydrotestosterone" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H30O2</p>          </body>        </notes>      </species>      <species id="M_5adtststerone_r" name="5alpha-Dihydrotestosterone" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H30O2</p>          </body>        </notes>      </species>      <species id="M_5adtststeroneglc_c" name="5alpha-Dihydrotestosterone glucuronide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H38O8</p>          </body>        </notes>      </species>      <species id="M_5adtststeroneglc_e" name="5alpha-Dihydrotestosterone glucuronide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H38O8</p>          </body>        </notes>      </species>      <species id="M_5adtststeroneglc_r" name="5alpha-Dihydrotestosterone glucuronide" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H38O8</p>          </body>        </notes>      </species>      <species id="M_5adtststerones_c" name="5alpha-Dihydrotestosterone sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H29O5S</p>          </body>        </notes>      </species>      <species id="M_5adtststerones_e" name="5alpha-Dihydrotestosterone sulfate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H29O5S</p>          </body>        </notes>      </species>      <species id="M_5aizc_c" name="5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N3O9P</p>          </body>        </notes>      </species>      <species id="M_5aop_c" name="5-Amino-4-oxopentanoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9NO3</p>          </body>        </notes>      </species>      <species id="M_5aop_m" name="5-Amino-4-oxopentanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9NO3</p>          </body>        </notes>      </species>      <species id="M_5dhf_c" name="pentaglutamyl folate (DHF)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H43N11O18</p>          </body>        </notes>      </species>      <species id="M_5dhf_e" name="pentaglutamyl folate (DHF)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H43N11O18</p>          </body>        </notes>      </species>      <species id="M_5dhf_l" name="pentaglutamyl folate (DHF)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H43N11O18</p>          </body>        </notes>      </species>      <species id="M_5dpmev_x" name="(R)-5-Diphosphomevalonate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10O10P2</p>          </body>        </notes>      </species>      <species id="M_5forthf_c" name="5-Formiminotetrahydrofolate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H22N8O6</p>          </body>        </notes>      </species>      <species id="M_5fthf_c" name="5-Formyltetrahydrofolate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H21N7O7</p>          </body>        </notes>      </species>      <species id="M_5fthf_e" name="5-Formyltetrahydrofolate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H21N7O7</p>          </body>        </notes>      </species>      <species id="M_5homeprazole_c" name="5 hydroxy omeprazole" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H19N3O4S</p>          </body>        </notes>      </species>      <species id="M_5homeprazole_e" name="5 hydroxy omeprazole" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H19N3O4S</p>          </body>        </notes>      </species>      <species id="M_5htrp_c" name="5-Hydroxy-L-tryptophan" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H12N2O3</p>          </body>        </notes>      </species>      <species id="M_5mdr1p_c" name="5-Methylthio-5-deoxy-D-ribose 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O7PS</p>          </body>        </notes>      </species>      <species id="M_5mdru1p_c" name="5-Methylthio-5-deoxy-D-ribulose 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O7PS</p>          </body>        </notes>      </species>      <species id="M_5mta_c" name="5-Methylthioadenosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H15N5O3S</p>          </body>        </notes>      </species>      <species id="M_5mthf_c" name="5-Methyltetrahydrofolate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H24N7O6</p>          </body>        </notes>      </species>      <species id="M_5mthf_e" name="5-Methyltetrahydrofolate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H24N7O6</p>          </body>        </notes>      </species>      <species id="M_5oxpro_c" name="5-Oxoproline" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H6NO3</p>          </body>        </notes>      </species>      <species id="M_5pmev_x" name="(R)-5-Phosphomevalonate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10O7P</p>          </body>        </notes>      </species>      <species id="M_5thf_c" name="pentaglutamyl folate (THF)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H45N11O18</p>          </body>        </notes>      </species>      <species id="M_5thf_e" name="pentaglutamyl folate (THF)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H45N11O18</p>          </body>        </notes>      </species>      <species id="M_5thf_l" name="pentaglutamyl folate (THF)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H45N11O18</p>          </body>        </notes>      </species>      <species id="M_6a2ohxnt_x" name="6-Amino-2-oxohexanoate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11NO3</p>          </body>        </notes>      </species>      <species id="M_6dhf_c" name="haxglutamyl folate (DHF)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C44H49N12O21</p>          </body>        </notes>      </species>      <species id="M_6dhf_e" name="haxglutamyl folate (DHF)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C44H49N12O21</p>          </body>        </notes>      </species>      <species id="M_6dhf_l" name="haxglutamyl folate (DHF)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C44H49N12O21</p>          </body>        </notes>      </species>      <species id="M_6pgc_c" name="6-Phospho-D-gluconate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10O10P</p>          </body>        </notes>      </species>      <species id="M_6pgl_c" name="6-phospho-D-glucono-1,5-lactone" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O9P</p>          </body>        </notes>      </species>      <species id="M_6pgl_r" name="6-phospho-D-glucono-1,5-lactone" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O9P</p>          </body>        </notes>      </species>      <species id="M_6thf_c" name="hexaglutamyl folate  (THF)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C44H51N12O21</p>          </body>        </notes>      </species>      <species id="M_6thf_e" name="hexaglutamyl folate  (THF)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C44H51N12O21</p>          </body>        </notes>      </species>      <species id="M_6thf_l" name="hexaglutamyl folate  (THF)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C44H51N12O21</p>          </body>        </notes>      </species>      <species id="M_7dhchsterol_c" name="7-Dehydrocholesterol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O</p>          </body>        </notes>      </species>      <species id="M_7dhchsterol_r" name="7-Dehydrocholesterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O</p>          </body>        </notes>      </species>      <species id="M_7dhf_c" name="heptaglutamyl folate (DHF)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C49H55N13O24</p>          </body>        </notes>      </species>      <species id="M_7dhf_e" name="heptaglutamyl folate (DHF)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C49H55N13O24</p>          </body>        </notes>      </species>      <species id="M_7dhf_l" name="heptaglutamyl folate (DHF)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C49H55N13O24</p>          </body>        </notes>      </species>      <species id="M_7thf_c" name="heptaglutamyl folate (THF)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C49H57N13O24</p>          </body>        </notes>      </species>      <species id="M_7thf_e" name="heptaglutamyl folate (THF)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C49H57N13O24</p>          </body>        </notes>      </species>      <species id="M_7thf_l" name="heptaglutamyl folate (THF)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C49H57N13O24</p>          </body>        </notes>      </species>      <species id="M_Asn_DASH_DASH_DASH_X_DASH_DASH_DASH_Ser_DASH_FSLASH_DASH_Thr_l" name="protein-linked asparagine residue (N-glycosylation site)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: XH</p>          </body>        </notes>      </species>      <species id="M_L2aadp6sa_c" name="L-2-Aminoadipate 6-semialdehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11NO3</p>          </body>        </notes>      </species>      <species id="M_L2aadp6sa_m" name="L-2-Aminoadipate 6-semialdehyde" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11NO3</p>          </body>        </notes>      </species>      <species id="M_L2aadp_c" name="L-2-Aminoadipate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10NO4</p>          </body>        </notes>      </species>      <species id="M_L2aadp_m" name="L-2-Aminoadipate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10NO4</p>          </body>        </notes>      </species>      <species id="M_Lcyst_c" name="L-Cysteate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6NO5S</p>          </body>        </notes>      </species>      <species id="M_Lfmkynr_c" name="L-Formylkynurenine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H12N2O4</p>          </body>        </notes>      </species>      <species id="M_Lkynr_c" name="L-Kynurenine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N2O3</p>          </body>        </notes>      </species>      <species id="M_Lpipecol_x" name="L-Pipecolate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11NO2</p>          </body>        </notes>      </species>      <species id="M_R1coa_DASH_hs_c" name="R group 1 Coenzyme A homo sapiens" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: XCO2C21H31N7O15P3S</p>          </body>        </notes>      </species>      <species id="M_R2coa_DASH_hs_c" name="R group 2 Coenzyme A homo sapiens" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: XCO2C21H31N7O15P3S</p>          </body>        </notes>      </species>      <species id="M_Rtotal2_c" name="R total 2 position" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR2</p>          </body>        </notes>      </species>      <species id="M_Rtotal2_e" name="R total 2 position" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR2</p>          </body>        </notes>      </species>      <species id="M_Rtotal2coa_c" name="R total 2 coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR2C21H31N7O15P3S</p>          </body>        </notes>      </species>      <species id="M_Rtotal2coa_m" name="R total 2 coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR2C21H31N7O15P3S</p>          </body>        </notes>      </species>      <species id="M_Rtotal2crn_c" name="R total 2 carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR2C7H14NO2</p>          </body>        </notes>      </species>      <species id="M_Rtotal2crn_m" name="R total 2 carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR2C7H14NO2</p>          </body>        </notes>      </species>      <species id="M_Rtotal3_c" name="R total 3 position" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR3</p>          </body>        </notes>      </species>      <species id="M_Rtotal3_e" name="R total 3 position" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR3</p>          </body>        </notes>      </species>      <species id="M_Rtotal3coa_c" name="R total 3 Coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR3C21H31N7O15P3S</p>          </body>        </notes>      </species>      <species id="M_Rtotal3coa_m" name="R total 3 Coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR3C21H31N7O15P3S</p>          </body>        </notes>      </species>      <species id="M_Rtotal3crn_c" name="R total 3 carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR3C7H14NO2</p>          </body>        </notes>      </species>      <species id="M_Rtotal3crn_m" name="R total 3 carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR3C7H14NO2</p>          </body>        </notes>      </species>      <species id="M_Rtotal_c" name="R total" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR</p>          </body>        </notes>      </species>      <species id="M_Rtotal_e" name="R total" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR</p>          </body>        </notes>      </species>      <species id="M_Rtotal_l" name="R total" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLR</p>          </body>        </notes>      </species>      <species id="M_Rtotalcoa_c" name="R total Coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLRC21H31N7O15P3S</p>          </body>        </notes>      </species>      <species id="M_Rtotalcoa_m" name="R total Coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLRC21H31N7O15P3S</p>          </body>        </notes>      </species>      <species id="M_Rtotalcrn_c" name="R total carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLRC7H14NO2</p>          </body>        </notes>      </species>      <species id="M_Rtotalcrn_m" name="R total carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2FULLRC7H14NO2</p>          </body>        </notes>      </species>      <species id="M_Sfglutth_c" name="S-Formylglutathione" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H16N3O7S</p>          </body>        </notes>      </species>      <species id="M_Ssq23epx_r" name="(S)-Squalene-2,3-epoxide" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C30H50O</p>          </body>        </notes>      </species>      <species id="M_Tyr_DASH_DASH_DASH_ggn_c" name="Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: XOH</p>          </body>        </notes>      </species>      <species id="M_aacoa_c" name="Acetoacetyl-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H36N7O18P3S</p>          </body>        </notes>      </species>      <species id="M_aacoa_m" name="Acetoacetyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H36N7O18P3S</p>          </body>        </notes>      </species>      <species id="M_aact_c" name="Aminoacetone" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H8NO</p>          </body>        </notes>      </species>      <species id="M_aact_m" name="Aminoacetone" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H8NO</p>          </body>        </notes>      </species>      <species id="M_abt_c" name="L-Arabinitol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H12O5</p>          </body>        </notes>      </species>      <species id="M_ac_c" name="Acetate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H3O2</p>          </body>        </notes>      </species>      <species id="M_ac_e" name="Acetate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H3O2</p>          </body>        </notes>      </species>      <species id="M_ac_m" name="Acetate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H3O2</p>          </body>        </notes>      </species>      <species id="M_acac_c" name="Acetoacetate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H5O3</p>          </body>        </notes>      </species>      <species id="M_acac_e" name="Acetoacetate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H5O3</p>          </body>        </notes>      </species>      <species id="M_acac_m" name="Acetoacetate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H5O3</p>          </body>        </notes>      </species>      <species id="M_acac_x" name="Acetoacetate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H5O3</p>          </body>        </notes>      </species>      <species id="M_acald_c" name="Acetaldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H4O</p>          </body>        </notes>      </species>      <species id="M_acald_m" name="Acetaldehyde" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H4O</p>          </body>        </notes>      </species>      <species id="M_acald_x" name="Acetaldehyde" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H4O</p>          </body>        </notes>      </species>      <species id="M_accoa_c" name="Acetyl-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H34N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_accoa_m" name="Acetyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H34N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_accoa_x" name="Acetyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H34N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_acetol_c" name="Acetol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6O2</p>          </body>        </notes>      </species>      <species id="M_acetone_c" name="Acetone" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6O</p>          </body>        </notes>      </species>      <species id="M_acetone_e" name="Acetone" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6O</p>          </body>        </notes>      </species>      <species id="M_acetone_m" name="Acetone" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6O</p>          </body>        </notes>      </species>      <species id="M_acgam1p_c" name="N-Acetyl-D-glucosamine 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H14NO9P</p>          </body>        </notes>      </species>      <species id="M_acgam6p_c" name="N-Acetyl-D-glucosamine 6-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H14NO9P</p>          </body>        </notes>      </species>      <species id="M_acgam_c" name="N-Acetyl-D-glucosamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H15NO6</p>          </body>        </notes>      </species>      <species id="M_acgam_l" name="N-Acetyl-D-glucosamine" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H15NO6</p>          </body>        </notes>      </species>      <species id="M_acmana_c" name="N-Acetyl-D-mannosamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H15NO6</p>          </body>        </notes>      </species>      <species id="M_acmanap_c" name="N-Acetyl-D-mannosamine 6-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H14NO9P</p>          </body>        </notes>      </species>      <species id="M_acnam_c" name="N-Acetylneuraminate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H18NO9</p>          </body>        </notes>      </species>      <species id="M_acnam_l" name="N-Acetylneuraminate" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H18NO9</p>          </body>        </notes>      </species>      <species id="M_acnamp_c" name="N-Acetylneuraminate 9-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H17NO12P</p>          </body>        </notes>      </species>      <species id="M_acrn_c" name="O-Acetylcarnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H17NO4</p>          </body>        </notes>      </species>      <species id="M_acrn_m" name="O-Acetylcarnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H17NO4</p>          </body>        </notes>      </species>      <species id="M_acrn_x" name="O-Acetylcarnitine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H17NO4</p>          </body>        </notes>      </species>      <species id="M_ade_c" name="Adenine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H5N5</p>          </body>        </notes>      </species>      <species id="M_adn_c" name="Adenosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N5O4</p>          </body>        </notes>      </species>      <species id="M_adn_e" name="Adenosine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N5O4</p>          </body>        </notes>      </species>      <species id="M_adn_m" name="Adenosine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N5O4</p>          </body>        </notes>      </species>      <species id="M_adp_c" name="ADP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O10P2</p>          </body>        </notes>      </species>      <species id="M_adp_e" name="ADP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O10P2</p>          </body>        </notes>      </species>      <species id="M_adp_m" name="ADP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O10P2</p>          </body>        </notes>      </species>      <species id="M_adp_n" name="ADP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O10P2</p>          </body>        </notes>      </species>      <species id="M_adp_x" name="ADP" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O10P2</p>          </body>        </notes>      </species>      <species id="M_adprib_c" name="ADPribose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H21N5O14P2</p>          </body>        </notes>      </species>      <species id="M_adrn_c" name="adrenic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H35O2</p>          </body>        </notes>      </species>      <species id="M_adrn_e" name="adrenic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H35O2</p>          </body>        </notes>      </species>      <species id="M_adrncoa_c" name="adrenyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H66N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_adrncoa_m" name="adrenyl coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H66N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_adrncoa_x" name="adrenyl coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H66N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_adrncrn_c" name="Adrenyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H49NO4</p>          </body>        </notes>      </species>      <species id="M_adrncrn_m" name="Adrenyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H49NO4</p>          </body>        </notes>      </species>      <species id="M_adrnl_c" name="Adrenaline" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H14NO3</p>          </body>        </notes>      </species>      <species id="M_aflatoxin_c" name="aflatoxin B1" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H12O6</p>          </body>        </notes>      </species>      <species id="M_aflatoxin_e" name="aflatoxin B1" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H12O6</p>          </body>        </notes>      </species>      <species id="M_ahcys_c" name="S-Adenosyl-L-homocysteine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H20N6O5S</p>          </body>        </notes>      </species>      <species id="M_ahcys_m" name="S-Adenosyl-L-homocysteine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H20N6O5S</p>          </body>        </notes>      </species>      <species id="M_ahcys_r" name="S-Adenosyl-L-homocysteine" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H20N6O5S</p>          </body>        </notes>      </species>      <species id="M_aicar_c" name="5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H13N4O8P</p>          </body>        </notes>      </species>      <species id="M_air_c" name="5-amino-1-(5-phospho-D-ribosyl)imidazole" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H12N3O7P</p>          </body>        </notes>      </species>      <species id="M_ak2lgchol_DASH_hs_e" name="1-alkyl 2-lysoglycerol 3-phosphocholine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H21O5NPFULLR</p>          </body>        </notes>      </species>      <species id="M_akg_c" name="2-Oxoglutarate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4O5</p>          </body>        </notes>      </species>      <species id="M_akg_m" name="2-Oxoglutarate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4O5</p>          </body>        </notes>      </species>      <species id="M_ala_DASH_DASH_DASH_B_c" name="beta-Alanine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2</p>          </body>        </notes>      </species>      <species id="M_ala_DASH_DASH_DASH_B_m" name="beta-Alanine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2</p>          </body>        </notes>      </species>      <species id="M_ala_DASH_DASH_DASH_D_c" name="D-Alanine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2</p>          </body>        </notes>      </species>      <species id="M_ala_DASH_DASH_DASH_D_x" name="D-Alanine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2</p>          </body>        </notes>      </species>      <species id="M_ala_DASH_DASH_DASH_L_c" name="L-Alanine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2</p>          </body>        </notes>      </species>      <species id="M_ala_DASH_DASH_DASH_L_e" name="L-Alanine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2</p>          </body>        </notes>      </species>      <species id="M_ala_DASH_DASH_DASH_L_x" name="L-Alanine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2</p>          </body>        </notes>      </species>      <species id="M_alpa_DASH_hs_c" name="lysophosphatidic acid (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6O5PFULLRCO2</p>          </body>        </notes>      </species>      <species id="M_alpam_m" name="S-aminomethyldihydrolipoamide" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H21N2OS2</p>          </body>        </notes>      </species>      <species id="M_alpro_m" name="S-Aminomethyldihydrolipoylprotein" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH6NS2X</p>          </body>        </notes>      </species>      <species id="M_am6sa_c" name="2-Aminomuconate 6-semialdehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H7NO3</p>          </body>        </notes>      </species>      <species id="M_amet_c" name="S-Adenosyl-L-methionine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H23N6O5S</p>          </body>        </notes>      </species>      <species id="M_amet_m" name="S-Adenosyl-L-methionine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H23N6O5S</p>          </body>        </notes>      </species>      <species id="M_amet_r" name="S-Adenosyl-L-methionine" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H23N6O5S</p>          </body>        </notes>      </species>      <species id="M_ametam_c" name="S-Adenosylmethioninamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H24N6O3S</p>          </body>        </notes>      </species>      <species id="M_amp_c" name="AMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O7P</p>          </body>        </notes>      </species>      <species id="M_amp_e" name="AMP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O7P</p>          </body>        </notes>      </species>      <species id="M_amp_m" name="AMP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O7P</p>          </body>        </notes>      </species>      <species id="M_amp_x" name="AMP" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O7P</p>          </body>        </notes>      </species>      <species id="M_amuco_c" name="2-Aminomuconate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H6NO4</p>          </body>        </notes>      </species>      <species id="M_andrstandn_r" name="androstanedione" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H28O2</p>          </body>        </notes>      </species>      <species id="M_andrstrn_r" name="Androsterone" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H30O2</p>          </body>        </notes>      </species>      <species id="M_antipyrene_c" name="antipyrene" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H12N2O</p>          </body>        </notes>      </species>      <species id="M_antipyrene_e" name="antipyrene" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H12N2O</p>          </body>        </notes>      </species>      <species id="M_apnnox_c" name="alpha-Pinene-oxide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16O</p>          </body>        </notes>      </species>      <species id="M_apnnox_e" name="alpha-Pinene-oxide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16O</p>          </body>        </notes>      </species>      <species id="M_apoC_DASH_DASH_DASH_Lys_DASH_btn_c" name="Holocarboxylase (biotin covalent bound to Lys residue of apoC)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H27N4O3SX</p>          </body>        </notes>      </species>      <species id="M_apoC_DASH_DASH_DASH_Lys_DASH_btn_m" name="Holocarboxylase (biotin covalent bound to Lys residue of apoC)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H27N4O3SX</p>          </body>        </notes>      </species>      <species id="M_apoC_DASH_DASH_DASH_Lys_c" name="Apocarboxylase (Lys residue)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13N2OX</p>          </body>        </notes>      </species>      <species id="M_apoC_DASH_DASH_DASH_Lys_m" name="Apocarboxylase (Lys residue)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13N2OX</p>          </body>        </notes>      </species>      <species id="M_apoC_c" name="Apocarboxlase (no lys residue)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: XH</p>          </body>        </notes>      </species>      <species id="M_apoC_m" name="Apocarboxlase (no lys residue)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: XH</p>          </body>        </notes>      </species>      <species id="M_appnn_c" name="(+)-alpha-Pinene" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16</p>          </body>        </notes>      </species>      <species id="M_appnn_e" name="(+)-alpha-Pinene" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16</p>          </body>        </notes>      </species>      <species id="M_aps_c" name="Adenosine 5&apos;-phosphosulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O10PS</p>          </body>        </notes>      </species>      <species id="M_arab_DASH_DASH_DASH_L_c" name="L-Arabinose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10O5</p>          </body>        </notes>      </species>      <species id="M_arab_DASH_DASH_DASH_L_e" name="L-Arabinose" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10O5</p>          </body>        </notes>      </species>      <species id="M_arach_c" name="Arachidic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H39O2</p>          </body>        </notes>      </species>      <species id="M_arach_e" name="Arachidic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H39O2</p>          </body>        </notes>      </species>      <species id="M_arachcoa_c" name="arachidyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H70N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_arachcoa_m" name="arachidyl coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H70N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_arachcoa_x" name="arachidyl coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H70N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_arachcrn_c" name="arachidyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H53NO4</p>          </body>        </notes>      </species>      <species id="M_arachcrn_m" name="arachidyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H53NO4</p>          </body>        </notes>      </species>      <species id="M_arachd_c" name="arachidonic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H31O2</p>          </body>        </notes>      </species>      <species id="M_arachd_e" name="arachidonic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H31O2</p>          </body>        </notes>      </species>      <species id="M_arachdcoa_c" name="C20:4-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_arachdcoa_m" name="C20:4-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_arachdcoa_x" name="C20:4-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_arachdcrn_c" name="C20:4 carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45NO4</p>          </body>        </notes>      </species>      <species id="M_arachdcrn_m" name="C20:4 carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45NO4</p>          </body>        </notes>      </species>      <species id="M_arg_DASH_DASH_DASH_L_c" name="L-Arginine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H15N4O2</p>          </body>        </notes>      </species>      <species id="M_arg_DASH_DASH_DASH_L_e" name="L-Arginine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H15N4O2</p>          </body>        </notes>      </species>      <species id="M_arg_DASH_DASH_DASH_L_m" name="L-Arginine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H15N4O2</p>          </body>        </notes>      </species>      <species id="M_argsuc_c" name="N(omega)-(L-Arginino)succinate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H17N4O6</p>          </body>        </notes>      </species>      <species id="M_ascb_DASH_DASH_DASH_L_c" name="L-Ascorbate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H8O6</p>          </body>        </notes>      </species>      <species id="M_ascb_DASH_DASH_DASH_L_e" name="L-Ascorbate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H8O6</p>          </body>        </notes>      </species>      <species id="M_asn_DASH_DASH_DASH_L_c" name="L-Asparagine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H8N2O3</p>          </body>        </notes>      </species>      <species id="M_asn_DASH_DASH_DASH_L_e" name="L-Asparagine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H8N2O3</p>          </body>        </notes>      </species>      <species id="M_asp_DASH_DASH_DASH_L_c" name="L-Aspartate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H6NO4</p>          </body>        </notes>      </species>      <species id="M_asp_DASH_DASH_DASH_L_e" name="L-Aspartate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H6NO4</p>          </body>        </notes>      </species>      <species id="M_asp_DASH_DASH_DASH_L_m" name="L-Aspartate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H6NO4</p>          </body>        </notes>      </species>      <species id="M_atp_c" name="ATP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O13P3</p>          </body>        </notes>      </species>      <species id="M_atp_e" name="ATP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O13P3</p>          </body>        </notes>      </species>      <species id="M_atp_m" name="ATP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O13P3</p>          </body>        </notes>      </species>      <species id="M_atp_n" name="ATP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O13P3</p>          </body>        </notes>      </species>      <species id="M_atp_x" name="ATP" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O13P3</p>          </body>        </notes>      </species>      <species id="M_b2coa_m" name="Crotonoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H36N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_bamppald_c" name="beta-Aminopropion aldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H8NO</p>          </body>        </notes>      </species>      <species id="M_betald_m" name="Betaine aldehyde" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H12NO</p>          </body>        </notes>      </species>      <species id="M_bhb_c" name="(R)-3-Hydroxybutanoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7O3</p>          </body>        </notes>      </species>      <species id="M_bhb_e" name="(R)-3-Hydroxybutanoate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7O3</p>          </body>        </notes>      </species>      <species id="M_bhb_m" name="(R)-3-Hydroxybutanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7O3</p>          </body>        </notes>      </species>      <species id="M_bildglcur_c" name="Bilirubin beta-diglucuronide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H50N4O18</p>          </body>        </notes>      </species>      <species id="M_bildglcur_e" name="Bilirubin beta-diglucuronide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H50N4O18</p>          </body>        </notes>      </species>      <species id="M_bildglcur_r" name="Bilirubin beta-diglucuronide" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H50N4O18</p>          </body>        </notes>      </species>      <species id="M_bilglcur_c" name="Bilirubin monoglucuronide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H44N4O12</p>          </body>        </notes>      </species>      <species id="M_bilglcur_e" name="Bilirubin monoglucuronide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H44N4O12</p>          </body>        </notes>      </species>      <species id="M_bilglcur_r" name="Bilirubin monoglucuronide" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H44N4O12</p>          </body>        </notes>      </species>      <species id="M_bilirub_c" name="Bilirubin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C33H34N4O6</p>          </body>        </notes>      </species>      <species id="M_bilirub_e" name="Bilirubin" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C33H34N4O6</p>          </body>        </notes>      </species>      <species id="M_bilirub_r" name="Bilirubin" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C33H34N4O6</p>          </body>        </notes>      </species>      <species id="M_biliverd_c" name="Biliverdin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C33H32N4O6</p>          </body>        </notes>      </species>      <species id="M_biocyt_c" name="Biocytin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H28N4O4S</p>          </body>        </notes>      </species>      <species id="M_biocyt_e" name="Biocytin" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H28N4O4S</p>          </body>        </notes>      </species>      <species id="M_biocyt_m" name="Biocytin" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H28N4O4S</p>          </body>        </notes>      </species>      <species id="M_biocyt_n" name="Biocytin" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H28N4O4S</p>          </body>        </notes>      </species>      <species id="M_btamp_c" name="Biotinyl-5&apos;-AMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H27N7O9PS</p>          </body>        </notes>      </species>      <species id="M_btamp_m" name="Biotinyl-5&apos;-AMP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H27N7O9PS</p>          </body>        </notes>      </species>      <species id="M_btcoa_m" name="Butanoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H38N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_btn_c" name="Biotin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H15N2O3S</p>          </body>        </notes>      </species>      <species id="M_btn_e" name="Biotin" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H15N2O3S</p>          </body>        </notes>      </species>      <species id="M_btn_m" name="Biotin" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H15N2O3S</p>          </body>        </notes>      </species>      <species id="M_btn_n" name="Biotin" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H15N2O3S</p>          </body>        </notes>      </species>      <species id="M_but_c" name="Butyrate (n-C4:0)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7O2</p>          </body>        </notes>      </species>      <species id="M_but_e" name="Butyrate (n-C4:0)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7O2</p>          </body>        </notes>      </species>      <species id="M_but_m" name="Butyrate (n-C4:0)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7O2</p>          </body>        </notes>      </species>      <species id="M_c226coa_c" name="cervonyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_c226coa_m" name="cervonyl coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_c226coa_x" name="cervonyl coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_c226crn_c" name="cervonyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H45NO4</p>          </body>        </notes>      </species>      <species id="M_c226crn_m" name="cervonyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H45NO4</p>          </body>        </notes>      </species>      <species id="M_ca2_c" name="Calcium" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Ca</p>          </body>        </notes>      </species>      <species id="M_ca2_e" name="Calcium" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Ca</p>          </body>        </notes>      </species>      <species id="M_cala_c" name="N-Carbamoyl-beta-alanine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7N2O3</p>          </body>        </notes>      </species>      <species id="M_camp_c" name="cAMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N5O6P</p>          </body>        </notes>      </species>      <species id="M_carveol_c" name="(E)-carveol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16O</p>          </body>        </notes>      </species>      <species id="M_carveol_e" name="(E)-carveol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16O</p>          </body>        </notes>      </species>      <species id="M_cbasp_c" name="N-Carbamoyl-L-aspartate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H6N2O5</p>          </body>        </notes>      </species>      <species id="M_cbp_c" name="Carbamoyl phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH2NO5P</p>          </body>        </notes>      </species>      <species id="M_cbp_m" name="Carbamoyl phosphate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH2NO5P</p>          </body>        </notes>      </species>      <species id="M_cdp_c" name="CDP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O11P2</p>          </body>        </notes>      </species>      <species id="M_cdp_m" name="CDP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O11P2</p>          </body>        </notes>      </species>      <species id="M_cdp_n" name="CDP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O11P2</p>          </body>        </notes>      </species>      <species id="M_cdpchol_c" name="CDPcholine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H25N4O11P2</p>          </body>        </notes>      </species>      <species id="M_cdpdag_DASH_hs_c" name="CDP diacylglycerol (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H17N3O11P2FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_cdpdag_DASH_hs_m" name="CDP diacylglycerol (homo sapiens)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H17N3O11P2FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_cdpea_c" name="CDPethanolamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H19N4O11P2</p>          </body>        </notes>      </species>      <species id="M_cgly_c" name="Cys-Gly" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10N2O3S</p>          </body>        </notes>      </species>      <species id="M_cgly_e" name="Cys-Gly" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10N2O3S</p>          </body>        </notes>      </species>      <species id="M_chlstol_r" name="Cholesta-7,24-dien-3beta-ol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O</p>          </body>        </notes>      </species>      <species id="M_chol_c" name="Choline" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H14NO</p>          </body>        </notes>      </species>      <species id="M_chol_m" name="Choline" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H14NO</p>          </body>        </notes>      </species>      <species id="M_chol_r" name="Choline" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H14NO</p>          </body>        </notes>      </species>      <species id="M_cholate_c" name="Cholate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H39O5</p>          </body>        </notes>      </species>      <species id="M_cholate_e" name="Cholate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H39O5</p>          </body>        </notes>      </species>      <species id="M_cholcoa_x" name="Choloyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H70N7O20P3S</p>          </body>        </notes>      </species>      <species id="M_cholcoads_x" name="3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C48H74N7O20P3S</p>          </body>        </notes>      </species>      <species id="M_cholcoaone_x" name="3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C48H74N7O21P3S</p>          </body>        </notes>      </species>      <species id="M_cholcoar_x" name="3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C48H76N7O20P3S</p>          </body>        </notes>      </species>      <species id="M_cholcoas_x" name="3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA(S)" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C48H76N7O20P3S</p>          </body>        </notes>      </species>      <species id="M_cholp_c" name="Choline phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H13NO4P</p>          </body>        </notes>      </species>      <species id="M_cholp_l" name="Choline phosphate" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H13NO4P</p>          </body>        </notes>      </species>      <species id="M_chsterol_c" name="Cholesterol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O</p>          </body>        </notes>      </species>      <species id="M_chsterol_e" name="Cholesterol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O</p>          </body>        </notes>      </species>      <species id="M_chsterol_m" name="Cholesterol" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O</p>          </body>        </notes>      </species>      <species id="M_chsterol_r" name="Cholesterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O</p>          </body>        </notes>      </species>      <species id="M_chsterols_c" name="cholesterol sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45O4S</p>          </body>        </notes>      </species>      <species id="M_cit_c" name="Citrate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H5O7</p>          </body>        </notes>      </species>      <species id="M_cit_e" name="Citrate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H5O7</p>          </body>        </notes>      </species>      <species id="M_cit_m" name="Citrate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H5O7</p>          </body>        </notes>      </species>      <species id="M_citr_DASH_DASH_DASH_L_c" name="L-Citrulline" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13N3O3</p>          </body>        </notes>      </species>      <species id="M_citr_DASH_DASH_DASH_L_m" name="L-Citrulline" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13N3O3</p>          </body>        </notes>      </species>      <species id="M_cl_c" name="Chloride" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Cl</p>          </body>        </notes>      </species>      <species id="M_cl_e" name="Chloride" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Cl</p>          </body>        </notes>      </species>      <species id="M_clpnd_c" name="clupanodonic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H33O2</p>          </body>        </notes>      </species>      <species id="M_clpnd_e" name="clupanodonic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H33O2</p>          </body>        </notes>      </species>      <species id="M_clpndcoa_c" name="clupanodonyl CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_clpndcoa_x" name="clupanodonyl CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_cmp_c" name="CMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O8P</p>          </body>        </notes>      </species>      <species id="M_cmp_e" name="CMP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O8P</p>          </body>        </notes>      </species>      <species id="M_cmp_m" name="CMP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O8P</p>          </body>        </notes>      </species>      <species id="M_cmp_n" name="CMP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O8P</p>          </body>        </notes>      </species>      <species id="M_cmusa_c" name="2-Amino-3-carboxymuconate semialdehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H6NO5</p>          </body>        </notes>      </species>      <species id="M_co2_c" name="CO2" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2</p>          </body>        </notes>      </species>      <species id="M_co2_m" name="CO2" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2</p>          </body>        </notes>      </species>      <species id="M_co2_r" name="CO2" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2</p>          </body>        </notes>      </species>      <species id="M_co2_x" name="CO2" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO2</p>          </body>        </notes>      </species>      <species id="M_co_c" name="Carbon monoxide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO</p>          </body>        </notes>      </species>      <species id="M_co_e" name="Carbon monoxide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CO</p>          </body>        </notes>      </species>      <species id="M_coa_c" name="Coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H32N7O16P3S</p>          </body>        </notes>      </species>      <species id="M_coa_m" name="Coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H32N7O16P3S</p>          </body>        </notes>      </species>      <species id="M_coa_x" name="Coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H32N7O16P3S</p>          </body>        </notes>      </species>      <species id="M_cortsn_r" name="Cortisone" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H28O5</p>          </body>        </notes>      </species>      <species id="M_coumarin_c" name="coumarin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H6O2</p>          </body>        </notes>      </species>      <species id="M_coumarin_e" name="coumarin" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H6O2</p>          </body>        </notes>      </species>      <species id="M_cpppg3_c" name="Coproporphyrinogen III" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C36H40N4O8</p>          </body>        </notes>      </species>      <species id="M_creat_c" name="Creatine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9N3O2</p>          </body>        </notes>      </species>      <species id="M_creat_e" name="Creatine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9N3O2</p>          </body>        </notes>      </species>      <species id="M_creat_m" name="Creatine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9N3O2</p>          </body>        </notes>      </species>      <species id="M_crm_DASH_hs_c" name="ceramide (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H36NO2FULLRCO</p>          </body>        </notes>      </species>      <species id="M_crm_DASH_hs_l" name="ceramide (homo sapiens)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H36NO2FULLRCO</p>          </body>        </notes>      </species>      <species id="M_crm_DASH_hs_r" name="ceramide (homo sapiens)" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H36NO2FULLRCO</p>          </body>        </notes>      </species>      <species id="M_crmp_DASH_hs_c" name="Ceramide 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H35NO5PFULLRCO</p>          </body>        </notes>      </species>      <species id="M_crmp_DASH_hs_e" name="Ceramide 1-phosphate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H35NO5PFULLRCO</p>          </body>        </notes>      </species>      <species id="M_crn_c" name="L-Carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H15NO3</p>          </body>        </notes>      </species>      <species id="M_crn_m" name="L-Carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H15NO3</p>          </body>        </notes>      </species>      <species id="M_crn_x" name="L-Carnitine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H15NO3</p>          </body>        </notes>      </species>      <species id="M_crtsl_r" name="Cortisol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H30O5</p>          </body>        </notes>      </species>      <species id="M_crvnc_c" name="cervonic acid, C22:6 n-3" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H31O2</p>          </body>        </notes>      </species>      <species id="M_crvnc_e" name="cervonic acid, C22:6 n-3" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H31O2</p>          </body>        </notes>      </species>      <species id="M_ctp_c" name="CTP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O14P3</p>          </body>        </notes>      </species>      <species id="M_ctp_m" name="CTP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O14P3</p>          </body>        </notes>      </species>      <species id="M_ctp_n" name="CTP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O14P3</p>          </body>        </notes>      </species>      <species id="M_cyan_c" name="Hydrogen cyanide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CHN</p>          </body>        </notes>      </species>      <species id="M_cyan_e" name="Hydrogen cyanide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CHN</p>          </body>        </notes>      </species>      <species id="M_cyan_m" name="Hydrogen cyanide" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CHN</p>          </body>        </notes>      </species>      <species id="M_cys_DASH_DASH_DASH_L_c" name="L-Cysteine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2S</p>          </body>        </notes>      </species>      <species id="M_cys_DASH_DASH_DASH_L_e" name="L-Cysteine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2S</p>          </body>        </notes>      </species>      <species id="M_cysam_c" name="Cysteamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H8NS</p>          </body>        </notes>      </species>      <species id="M_cyst_DASH_DASH_DASH_L_c" name="L-Cystathionine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H14N2O4S</p>          </body>        </notes>      </species>      <species id="M_cytd_c" name="Cytidine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H13N3O5</p>          </body>        </notes>      </species>      <species id="M_cytd_e" name="Cytidine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H13N3O5</p>          </body>        </notes>      </species>      <species id="M_cytd_m" name="Cytidine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H13N3O5</p>          </body>        </notes>      </species>      <species id="M_dad_DASH_DASH_DASH_2_c" name="Deoxyadenosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N5O3</p>          </body>        </notes>      </species>      <species id="M_dadp_c" name="dADP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O9P2</p>          </body>        </notes>      </species>      <species id="M_dadp_m" name="dADP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O9P2</p>          </body>        </notes>      </species>      <species id="M_dadp_n" name="dADP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O9P2</p>          </body>        </notes>      </species>      <species id="M_dag_DASH_hs_c" name="diacylglycerol (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6OFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_dag_DASH_hs_e" name="diacylglycerol (homo sapiens)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6OFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_dag_DASH_hs_n" name="diacylglycerol (homo sapiens)" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6OFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_damp_c" name="dAMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O6P</p>          </body>        </notes>      </species>      <species id="M_datp_c" name="dATP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O12P3</p>          </body>        </notes>      </species>      <species id="M_datp_m" name="dATP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O12P3</p>          </body>        </notes>      </species>      <species id="M_datp_n" name="dATP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O12P3</p>          </body>        </notes>      </species>      <species id="M_dcacoa_c" name="Decanoyl-CoA (n-C10:0CoA)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C31H50N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_dcamp_c" name="N6-(1,2-Dicarboxyethyl)-AMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H14N5O11P</p>          </body>        </notes>      </species>      <species id="M_dcdp_c" name="dCDP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O10P2</p>          </body>        </notes>      </species>      <species id="M_dcdp_m" name="dCDP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O10P2</p>          </body>        </notes>      </species>      <species id="M_dcdp_n" name="dCDP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O10P2</p>          </body>        </notes>      </species>      <species id="M_dcholcoa_x" name="chenodeoxycholoyl coenzyme a" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H70N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_dcmp_c" name="dCMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O7P</p>          </body>        </notes>      </species>      <species id="M_dcmp_n" name="dCMP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O7P</p>          </body>        </notes>      </species>      <species id="M_dcsptn1_c" name="docosa-4,7,10,13,16-pentaenoic acid (n-6)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H33O2</p>          </body>        </notes>      </species>      <species id="M_dcsptn1_e" name="docosa-4,7,10,13,16-pentaenoic acid (n-6)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H33O2</p>          </body>        </notes>      </species>      <species id="M_dcsptn1coa_c" name="docosa-4,7,10,13,16-pentaenoyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_dcsptn1coa_m" name="docosa-4,7,10,13,16-pentaenoyl coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_dcsptn1coa_x" name="docosa-4,7,10,13,16-pentaenoyl coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C43H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_dcsptn1crn_c" name="docosa-4,7,10,13,16-pentaenoyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H47NO4</p>          </body>        </notes>      </species>      <species id="M_dcsptn1crn_m" name="docosa-4,7,10,13,16-pentaenoyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H47NO4</p>          </body>        </notes>      </species>      <species id="M_dctp_c" name="dCTP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O13P3</p>          </body>        </notes>      </species>      <species id="M_dctp_m" name="dCTP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O13P3</p>          </body>        </notes>      </species>      <species id="M_dctp_n" name="dCTP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N3O13P3</p>          </body>        </notes>      </species>      <species id="M_dcyt_c" name="Deoxycytidine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H13N3O4</p>          </body>        </notes>      </species>      <species id="M_dcyt_n" name="Deoxycytidine" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H13N3O4</p>          </body>        </notes>      </species>      <species id="M_ddcacoa_c" name="Dodecanoyl-CoA (n-C12:0CoA)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C33H54N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_ddsmsterol_r" name="7-Dehydrodesmosterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H42O</p>          </body>        </notes>      </species>      <species id="M_debrisoquine_c" name="debrisoquine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H14N3</p>          </body>        </notes>      </species>      <species id="M_debrisoquine_e" name="debrisoquine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H14N3</p>          </body>        </notes>      </species>      <species id="M_dgchol_c" name="Chenodeoxyglycocholate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H43NO5</p>          </body>        </notes>      </species>      <species id="M_dgchol_e" name="Chenodeoxyglycocholate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H43NO5</p>          </body>        </notes>      </species>      <species id="M_dgchol_x" name="Chenodeoxyglycocholate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H43NO5</p>          </body>        </notes>      </species>      <species id="M_dgcholcoa_x" name="Chenodeoxyglycocholoyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H70N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_dgdp_c" name="dGDP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O10P2</p>          </body>        </notes>      </species>      <species id="M_dgdp_m" name="dGDP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O10P2</p>          </body>        </notes>      </species>      <species id="M_dgdp_n" name="dGDP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O10P2</p>          </body>        </notes>      </species>      <species id="M_dgmp_c" name="dGMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O7P</p>          </body>        </notes>      </species>      <species id="M_dgmp_m" name="dGMP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O7P</p>          </body>        </notes>      </species>      <species id="M_dgsn_c" name="Deoxyguanosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N5O4</p>          </body>        </notes>      </species>      <species id="M_dgsn_m" name="Deoxyguanosine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N5O4</p>          </body>        </notes>      </species>      <species id="M_dgtp_c" name="dGTP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O13P3</p>          </body>        </notes>      </species>      <species id="M_dgtp_m" name="dGTP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O13P3</p>          </body>        </notes>      </species>      <species id="M_dgtp_n" name="dGTP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O13P3</p>          </body>        </notes>      </species>      <species id="M_dhap_c" name="Dihydroxyacetone phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O6P</p>          </body>        </notes>      </species>      <species id="M_dhbpt_c" name="6,7-Dihydrobiopterin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H13N5O3</p>          </body>        </notes>      </species>      <species id="M_dhcholestanate_m" name="3alpha,7alpha-Dihydroxy-5beta-cholestanate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45O4</p>          </body>        </notes>      </species>      <species id="M_dhcholestanate_x" name="3alpha,7alpha-Dihydroxy-5beta-cholestanate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45O4</p>          </body>        </notes>      </species>      <species id="M_dhcholestancoa_x" name="3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C48H76N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_dhcholoylcoa_x" name="3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C48H74N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_dhcrm_DASH_hs_c" name="dihydroceramide (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H38NO2FULLRCO</p>          </body>        </notes>      </species>      <species id="M_dhdascb_c" name="Dehydroascorbate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H6O6</p>          </body>        </notes>      </species>      <species id="M_dhdascb_e" name="Dehydroascorbate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H6O6</p>          </body>        </notes>      </species>      <species id="M_dhea_c" name="Dehydroepiandrosterone" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H28O2</p>          </body>        </notes>      </species>      <species id="M_dheas_c" name="Dehydroepiandrosterone sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H27O5S</p>          </body>        </notes>      </species>      <species id="M_dhf_c" name="7,8-Dihydrofolate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H19N7O6</p>          </body>        </notes>      </species>      <species id="M_dhf_e" name="7,8-Dihydrofolate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H19N7O6</p>          </body>        </notes>      </species>      <species id="M_dhf_l" name="7,8-Dihydrofolate" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H19N7O6</p>          </body>        </notes>      </species>      <species id="M_dhlam_m" name="Dihydrolipoamide" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H17NOS2</p>          </body>        </notes>      </species>      <species id="M_dhlpro_m" name="Dihydrolipolprotein" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2S2X</p>          </body>        </notes>      </species>      <species id="M_dhocholoylcoa_x" name="3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C48H74N7O20P3S</p>          </body>        </notes>      </species>      <species id="M_dhor_DASH_DASH_DASH_S_c" name="(S)-Dihydroorotate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H5N2O4</p>          </body>        </notes>      </species>      <species id="M_didp_c" name="dIDP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O10P2</p>          </body>        </notes>      </species>      <species id="M_didp_n" name="dIDP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O10P2</p>          </body>        </notes>      </species>      <species id="M_din_c" name="Deoxyinosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N4O4</p>          </body>        </notes>      </species>      <species id="M_ditp_c" name="dITP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O13P3</p>          </body>        </notes>      </species>      <species id="M_ditp_n" name="dITP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O13P3</p>          </body>        </notes>      </species>      <species id="M_dkmpp_c" name="2,3-diketo-5-methylthio-1-phosphopentane" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O6PS</p>          </body>        </notes>      </species>      <species id="M_dlnlcg_c" name="dihomo-gamma-linolenic acid (n-6)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H33O2</p>          </body>        </notes>      </species>      <species id="M_dlnlcg_e" name="dihomo-gamma-linolenic acid (n-6)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H33O2</p>          </body>        </notes>      </species>      <species id="M_dlnlcgcoa_c" name="dihomo-gamma-linolenyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_dlnlcgcoa_m" name="dihomo-gamma-linolenyl coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_dlnlcgcrn_c" name="dihomo-gamma-linolenyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H47NO4</p>          </body>        </notes>      </species>      <species id="M_dlnlcgcrn_m" name="dihomo-gamma-linolenyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H47NO4</p>          </body>        </notes>      </species>      <species id="M_dmantipyrine_c" name="demethylated antipyrine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H10N2O</p>          </body>        </notes>      </species>      <species id="M_dmantipyrine_e" name="demethylated antipyrine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H10N2O</p>          </body>        </notes>      </species>      <species id="M_dmgly_c" name="N,N-Dimethylglycine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2</p>          </body>        </notes>      </species>      <species id="M_dmgly_m" name="N,N-Dimethylglycine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2</p>          </body>        </notes>      </species>      <species id="M_dmpp_x" name="Dimethylallyl diphosphate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9O7P2</p>          </body>        </notes>      </species>      <species id="M_dnad_c" name="Deamino-NAD+" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H24N6O15P2</p>          </body>        </notes>      </species>      <species id="M_dnad_n" name="Deamino-NAD+" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H24N6O15P2</p>          </body>        </notes>      </species>      <species id="M_dolglcp_DASH_L_c" name="Dolichyl beta-D-glucosyl phosphate, human liver homolog" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C1140H1868O90P10</p>          </body>        </notes>      </species>      <species id="M_dolglcp_DASH_L_r" name="Dolichyl beta-D-glucosyl phosphate, human liver homolog" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C1140H1868O90P10</p>          </body>        </notes>      </species>      <species id="M_dolglcp_DASH_U_c" name="Dolichyl beta-D-glucosyl phosphate, human uterine homolog" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C1085H1780O90P10</p>          </body>        </notes>      </species>      <species id="M_dolglcp_DASH_U_r" name="Dolichyl beta-D-glucosyl phosphate, human uterine homolog" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C1085H1780O90P10</p>          </body>        </notes>      </species>      <species id="M_dolp_DASH_L_c" name="Dolichol phosphate, human liver homolog" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C1080H1758O40P10</p>          </body>        </notes>      </species>      <species id="M_dolp_DASH_L_r" name="Dolichol phosphate, human liver homolog" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C1080H1758O40P10</p>          </body>        </notes>      </species>      <species id="M_dolp_DASH_U_c" name="Dolichol phosphate, human uterine homolog" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C1025H1670O40P10</p>          </body>        </notes>      </species>      <species id="M_dolp_DASH_U_r" name="Dolichol phosphate, human uterine homolog" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C1025H1670O40P10</p>          </body>        </notes>      </species>      <species id="M_dopa_c" name="Dopamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H12NO2</p>          </body>        </notes>      </species>      <species id="M_dopa_e" name="Dopamine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H12NO2</p>          </body>        </notes>      </species>      <species id="M_dopasf_c" name="Dopamine 3-O-sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H11NO5S</p>          </body>        </notes>      </species>      <species id="M_dopasf_e" name="Dopamine 3-O-sulfate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H11NO5S</p>          </body>        </notes>      </species>      <species id="M_drib_c" name="Deoxyribose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10O4</p>          </body>        </notes>      </species>      <species id="M_dsmsterol_r" name="Desmosterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O</p>          </body>        </notes>      </species>      <species id="M_dtdp_c" name="dTDP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O11P2</p>          </body>        </notes>      </species>      <species id="M_dtdp_m" name="dTDP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O11P2</p>          </body>        </notes>      </species>      <species id="M_dtdp_n" name="dTDP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O11P2</p>          </body>        </notes>      </species>      <species id="M_dtmp_c" name="dTMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O8P</p>          </body>        </notes>      </species>      <species id="M_dtmp_m" name="dTMP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O8P</p>          </body>        </notes>      </species>      <species id="M_dttp_c" name="dTTP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O14P3</p>          </body>        </notes>      </species>      <species id="M_dttp_m" name="dTTP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O14P3</p>          </body>        </notes>      </species>      <species id="M_dttp_n" name="dTTP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O14P3</p>          </body>        </notes>      </species>      <species id="M_dudp_c" name="dUDP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O11P2</p>          </body>        </notes>      </species>      <species id="M_dudp_m" name="dUDP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O11P2</p>          </body>        </notes>      </species>      <species id="M_dudp_n" name="dUDP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O11P2</p>          </body>        </notes>      </species>      <species id="M_dump_c" name="dUMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O8P</p>          </body>        </notes>      </species>      <species id="M_dump_m" name="dUMP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O8P</p>          </body>        </notes>      </species>      <species id="M_dump_n" name="dUMP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O8P</p>          </body>        </notes>      </species>      <species id="M_duri_c" name="Deoxyuridine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N2O5</p>          </body>        </notes>      </species>      <species id="M_duri_m" name="Deoxyuridine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N2O5</p>          </body>        </notes>      </species>      <species id="M_dutp_c" name="dUTP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O14P3</p>          </body>        </notes>      </species>      <species id="M_dutp_m" name="dUTP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O14P3</p>          </body>        </notes>      </species>      <species id="M_dutp_n" name="dUTP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O14P3</p>          </body>        </notes>      </species>      <species id="M_dxtrn_c" name="phosphorylase-limit dextrin (glycogenin-1,6{4[1,4-Glc], 4[1,4-Glc]})" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C48H81O41X</p>          </body>        </notes>      </species>      <species id="M_e4hglu_m" name="L-erythro-4-Hydroxyglutamate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H8NO5</p>          </body>        </notes>      </species>      <species id="M_e4p_c" name="D-Erythrose 4-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H7O7P</p>          </body>        </notes>      </species>      <species id="M_eaflatoxin_c" name="8,9 epxoy aflatoxin B1" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H12O7</p>          </body>        </notes>      </species>      <species id="M_eaflatoxin_e" name="8,9 epxoy aflatoxin B1" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H12O7</p>          </body>        </notes>      </species>      <species id="M_eandrstrn_r" name="epiandrosterone" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H28O3</p>          </body>        </notes>      </species>      <species id="M_ebastine_c" name="ebastine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C32H39NO2</p>          </body>        </notes>      </species>      <species id="M_ebastine_e" name="ebastine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C32H39NO2</p>          </body>        </notes>      </species>      <species id="M_ebastine_r" name="ebastine" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C32H39NO2</p>          </body>        </notes>      </species>      <species id="M_ebastineoh_c" name="hydroxylated ebastine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C32H39NO3</p>          </body>        </notes>      </species>      <species id="M_ebastineoh_e" name="hydroxylated ebastine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C32H39NO3</p>          </body>        </notes>      </species>      <species id="M_ebastineoh_r" name="hydroxylated ebastine" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C32H39NO3</p>          </body>        </notes>      </species>      <species id="M_eicostet_c" name="eicosatetranoic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H31O2</p>          </body>        </notes>      </species>      <species id="M_eicostet_e" name="eicosatetranoic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H31O2</p>          </body>        </notes>      </species>      <species id="M_eicostetcoa_c" name="eicosatetranoyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_eicostetcoa_m" name="eicosatetranoyl coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_eicostetcrn_c" name="Eicosatetranoyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45NO4</p>          </body>        </notes>      </species>      <species id="M_eicostetcrn_m" name="Eicosatetranoyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45NO4</p>          </body>        </notes>      </species>      <species id="M_elaid_c" name="elaidic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H33O2</p>          </body>        </notes>      </species>      <species id="M_elaid_e" name="elaidic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H33O2</p>          </body>        </notes>      </species>      <species id="M_elaidcrn_c" name="Elaidic carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H47NO4</p>          </body>        </notes>      </species>      <species id="M_elaidcrn_m" name="Elaidic carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H47NO4</p>          </body>        </notes>      </species>      <species id="M_estradiol_c" name="Estradiol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H24O2</p>          </body>        </notes>      </species>      <species id="M_estradiol_r" name="Estradiol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H24O2</p>          </body>        </notes>      </species>      <species id="M_estradiolglc_c" name="estradiol glucuronide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H32O8</p>          </body>        </notes>      </species>      <species id="M_estradiolglc_e" name="estradiol glucuronide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H32O8</p>          </body>        </notes>      </species>      <species id="M_estradiolglc_r" name="estradiol glucuronide" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H32O8</p>          </body>        </notes>      </species>      <species id="M_estrone_c" name="Estrone" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H22O2</p>          </body>        </notes>      </species>      <species id="M_estrone_r" name="Estrone" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H22O2</p>          </body>        </notes>      </species>      <species id="M_estroneglc_c" name="estrone glucuronide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H30O8</p>          </body>        </notes>      </species>      <species id="M_estroneglc_e" name="estrone glucuronide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H30O8</p>          </body>        </notes>      </species>      <species id="M_estroneglc_r" name="estrone glucuronide" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H30O8</p>          </body>        </notes>      </species>      <species id="M_estrones_c" name="Estrone 3-sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H21O5S</p>          </body>        </notes>      </species>      <species id="M_estrones_e" name="Estrone 3-sulfate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H21O5S</p>          </body>        </notes>      </species>      <species id="M_etfox_m" name="Electron transfer flavoprotein oxidized" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: R</p>          </body>        </notes>      </species>      <species id="M_etfrd_m" name="Electron transfer flavoprotein reduced" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: RH2</p>          </body>        </notes>      </species>      <species id="M_etha_c" name="Ethanolamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H8NO</p>          </body>        </notes>      </species>      <species id="M_ethamp_c" name="Ethanolamine phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H7NO4P</p>          </body>        </notes>      </species>      <species id="M_ethamp_r" name="Ethanolamine phosphate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H7NO4P</p>          </body>        </notes>      </species>      <species id="M_etoh_c" name="Ethanol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H6O</p>          </body>        </notes>      </species>      <species id="M_etoh_e" name="Ethanol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H6O</p>          </body>        </notes>      </species>      <species id="M_etoh_x" name="Ethanol" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H6O</p>          </body>        </notes>      </species>      <species id="M_f1p_c" name="D-Fructose 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_f26bp_c" name="D-Fructose 2,6-bisphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10O12P2</p>          </body>        </notes>      </species>      <species id="M_f6p_c" name="D-Fructose 6-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_fad_c" name="Flavin adenine dinucleotide oxidized" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H31N9O15P2</p>          </body>        </notes>      </species>      <species id="M_fad_m" name="Flavin adenine dinucleotide oxidized" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H31N9O15P2</p>          </body>        </notes>      </species>      <species id="M_fad_r" name="Flavin adenine dinucleotide oxidized" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H31N9O15P2</p>          </body>        </notes>      </species>      <species id="M_fad_x" name="Flavin adenine dinucleotide oxidized" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H31N9O15P2</p>          </body>        </notes>      </species>      <species id="M_fadh2_c" name="Flavin adenine dinucleotide reduced" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H33N9O15P2</p>          </body>        </notes>      </species>      <species id="M_fadh2_m" name="Flavin adenine dinucleotide reduced" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H33N9O15P2</p>          </body>        </notes>      </species>      <species id="M_fadh2_r" name="Flavin adenine dinucleotide reduced" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H33N9O15P2</p>          </body>        </notes>      </species>      <species id="M_fadh2_x" name="Flavin adenine dinucleotide reduced" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H33N9O15P2</p>          </body>        </notes>      </species>      <species id="M_fald_c" name="Formaldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH2O</p>          </body>        </notes>      </species>      <species id="M_fald_m" name="Formaldehyde" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH2O</p>          </body>        </notes>      </species>      <species id="M_fdp_c" name="D-Fructose 1,6-bisphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10O12P2</p>          </body>        </notes>      </species>      <species id="M_fe2_c" name="Fe2+" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Fe</p>          </body>        </notes>      </species>      <species id="M_fe2_e" name="Fe2+" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Fe</p>          </body>        </notes>      </species>      <species id="M_fe2_m" name="Fe2+" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Fe</p>          </body>        </notes>      </species>      <species id="M_fe3_e" name="Fe3+" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Fe</p>          </body>        </notes>      </species>      <species id="M_fgam_c" name="N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H13N2O9P</p>          </body>        </notes>      </species>      <species id="M_ficytC_m" name="Ferricytochrome c" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C42H54FeN8O6S2</p>          </body>        </notes>      </species>      <species id="M_fmn_c" name="FMN" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H19N4O9P</p>          </body>        </notes>      </species>      <species id="M_focytC_m" name="Ferrocytochrome C" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C42H54FeN8O6S2</p>          </body>        </notes>      </species>      <species id="M_fol_c" name="Folate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H18N7O6</p>          </body>        </notes>      </species>      <species id="M_fol_e" name="Folate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H18N7O6</p>          </body>        </notes>      </species>      <species id="M_for_c" name="Formate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH1O2</p>          </body>        </notes>      </species>      <species id="M_for_r" name="Formate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH1O2</p>          </body>        </notes>      </species>      <species id="M_forglu_c" name="N-Formimidoyl-L-glutamate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H8N2O4</p>          </body>        </notes>      </species>      <species id="M_fpram_c" name="2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H15N3O8P</p>          </body>        </notes>      </species>      <species id="M_fprica_c" name="5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N4O9P</p>          </body>        </notes>      </species>      <species id="M_frdp_r" name="Farnesyl diphosphate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H25O7P2</p>          </body>        </notes>      </species>      <species id="M_frdp_x" name="Farnesyl diphosphate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H25O7P2</p>          </body>        </notes>      </species>      <species id="M_fru_c" name="D-Fructose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_fru_e" name="D-Fructose" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_fuc_DASH_DASH_DASH_L_e" name="L-Fucose" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O5</p>          </body>        </notes>      </species>      <species id="M_fum_c" name="Fumarate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H2O4</p>          </body>        </notes>      </species>      <species id="M_fum_m" name="Fumarate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H2O4</p>          </body>        </notes>      </species>      <species id="M_g1p_c" name="D-Glucose 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_g3p_c" name="Glyceraldehyde 3-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O6P</p>          </body>        </notes>      </species>      <species id="M_g3pc_c" name="sn-Glycero-3-phosphocholine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H20NO6P</p>          </body>        </notes>      </species>      <species id="M_g6p_c" name="D-Glucose 6-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_g6p_r" name="D-Glucose 6-phosphate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_gal1p_c" name="alpha-D-Galactose 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_gal_c" name="D-Galactose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_gal_e" name="D-Galactose" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_gal_l" name="D-Galactose" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_gam6p_c" name="D-Glucosamine 6-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13NO8P</p>          </body>        </notes>      </species>      <species id="M_gam_c" name="D-Glucosamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H14NO5</p>          </body>        </notes>      </species>      <species id="M_gam_e" name="D-Glucosamine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H14NO5</p>          </body>        </notes>      </species>      <species id="M_gar_c" name="N1-(5-Phospho-D-ribosyl)glycinamide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H14N2O8P</p>          </body>        </notes>      </species>      <species id="M_gcald_c" name="Glycolaldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H4O2</p>          </body>        </notes>      </species>      <species id="M_gchola_c" name="glycocholate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H43NO6</p>          </body>        </notes>      </species>      <species id="M_gchola_e" name="glycocholate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H43NO6</p>          </body>        </notes>      </species>      <species id="M_gchola_x" name="glycocholate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H43NO6</p>          </body>        </notes>      </species>      <species id="M_gdchola_c" name="glycochenodeoxycholate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H43NO5</p>          </body>        </notes>      </species>      <species id="M_gdchola_e" name="glycochenodeoxycholate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H43NO5</p>          </body>        </notes>      </species>      <species id="M_gdchola_x" name="glycochenodeoxycholate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H43NO5</p>          </body>        </notes>      </species>      <species id="M_gdp_c" name="GDP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O11P2</p>          </body>        </notes>      </species>      <species id="M_gdp_e" name="GDP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O11P2</p>          </body>        </notes>      </species>      <species id="M_gdp_m" name="GDP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O11P2</p>          </body>        </notes>      </species>      <species id="M_gdp_n" name="GDP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O11P2</p>          </body>        </notes>      </species>      <species id="M_ggn_c" name="primed glycogenin (glycogenin-8[1,4-Glc])" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C48H81O41X</p>          </body>        </notes>      </species>      <species id="M_glc_DASH_DASH_DASH_D_c" name="D-Glucose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_glc_DASH_DASH_DASH_D_e" name="D-Glucose" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_glc_DASH_DASH_DASH_D_r" name="D-Glucose" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_glcur_c" name="D-Glucuronate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O7</p>          </body>        </notes>      </species>      <species id="M_glcur_l" name="D-Glucuronate" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O7</p>          </body>        </notes>      </species>      <species id="M_glcur_r" name="D-Glucuronate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O7</p>          </body>        </notes>      </species>      <species id="M_gln_DASH_DASH_DASH_L_c" name="L-Glutamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10N2O3</p>          </body>        </notes>      </species>      <species id="M_gln_DASH_DASH_DASH_L_e" name="L-Glutamine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10N2O3</p>          </body>        </notes>      </species>      <species id="M_gln_DASH_DASH_DASH_L_m" name="L-Glutamine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10N2O3</p>          </body>        </notes>      </species>      <species id="M_glu5p_m" name="L-Glutamate 5-phosphate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H8NO7P</p>          </body>        </notes>      </species>      <species id="M_glu5sa_m" name="L-Glutamate 5-semialdehyde" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9NO3</p>          </body>        </notes>      </species>      <species id="M_glu_DASH_DASH_DASH_L_c" name="L-Glutamate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H8NO4</p>          </body>        </notes>      </species>      <species id="M_glu_DASH_DASH_DASH_L_e" name="L-Glutamate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H8NO4</p>          </body>        </notes>      </species>      <species id="M_glu_DASH_DASH_DASH_L_l" name="L-Glutamate" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H8NO4</p>          </body>        </notes>      </species>      <species id="M_glu_DASH_DASH_DASH_L_m" name="L-Glutamate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H8NO4</p>          </body>        </notes>      </species>      <species id="M_glu_DASH_DASH_DASH_L_r" name="L-Glutamate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H8NO4</p>          </body>        </notes>      </species>      <species id="M_gluala_e" name="5-L-Glutamyl-L-alanine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H13N2O5</p>          </body>        </notes>      </species>      <species id="M_glucys_c" name="gamma-L-Glutamyl-L-cysteine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H13N2O5S</p>          </body>        </notes>      </species>      <species id="M_gluside_DASH_hs_c" name="glucocerebroside (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H46NO7FULLRCO</p>          </body>        </notes>      </species>      <species id="M_gluside_DASH_hs_r" name="glucocerebroside (homo sapiens)" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H46NO7FULLRCO</p>          </body>        </notes>      </species>      <species id="M_glutcoa_m" name="Glutaryl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H37N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_glx_c" name="Glyoxylate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H1O3</p>          </body>        </notes>      </species>      <species id="M_glx_x" name="Glyoxylate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H1O3</p>          </body>        </notes>      </species>      <species id="M_gly_c" name="Glycine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H5NO2</p>          </body>        </notes>      </species>      <species id="M_gly_e" name="Glycine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H5NO2</p>          </body>        </notes>      </species>      <species id="M_gly_m" name="Glycine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H5NO2</p>          </body>        </notes>      </species>      <species id="M_gly_x" name="Glycine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H5NO2</p>          </body>        </notes>      </species>      <species id="M_glyald_c" name="D-Glyceraldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6O3</p>          </body>        </notes>      </species>      <species id="M_glyb_c" name="Glycine betaine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H11NO2</p>          </body>        </notes>      </species>      <species id="M_glyb_e" name="Glycine betaine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H11NO2</p>          </body>        </notes>      </species>      <species id="M_glyb_m" name="Glycine betaine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H11NO2</p>          </body>        </notes>      </species>      <species id="M_glyc3p_c" name="Glycerol 3-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7O6P</p>          </body>        </notes>      </species>      <species id="M_glyc_DASH_DASH_DASH_R_c" name="(R)-Glycerate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O4</p>          </body>        </notes>      </species>      <species id="M_glyc_DASH_DASH_DASH_S_c" name="(S)-Glycerate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O4</p>          </body>        </notes>      </species>      <species id="M_glyc_DASH_DASH_DASH_S_e" name="(S)-Glycerate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O4</p>          </body>        </notes>      </species>      <species id="M_glyc_c" name="Glycerol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H8O3</p>          </body>        </notes>      </species>      <species id="M_glyc_e" name="Glycerol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H8O3</p>          </body>        </notes>      </species>      <species id="M_glyclt_c" name="Glycolate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H3O3</p>          </body>        </notes>      </species>      <species id="M_glyclt_x" name="Glycolate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H3O3</p>          </body>        </notes>      </species>      <species id="M_glygn1_c" name="glycogen, structure 1 (glycogenin-11[1,4-Glc])" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C66H111O56X</p>          </body>        </notes>      </species>      <species id="M_glygn2_c" name="glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C66H111O56X</p>          </body>        </notes>      </species>      <species id="M_glygn2_e" name="glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C66H111O56X</p>          </body>        </notes>      </species>      <species id="M_glygn3_c" name="glycogen, structure 3 (glycogenin-7[1,4-Glc])" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C42H71O36X</p>          </body>        </notes>      </species>      <species id="M_glygn4_e" name="glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]})" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H31O16X</p>          </body>        </notes>      </species>      <species id="M_gmp_c" name="GMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O8P</p>          </body>        </notes>      </species>      <species id="M_gmp_e" name="GMP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O8P</p>          </body>        </notes>      </species>      <species id="M_grdp_x" name="Geranyl diphosphate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H17O7P2</p>          </body>        </notes>      </species>      <species id="M_gsn_c" name="Guanosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N5O5</p>          </body>        </notes>      </species>      <species id="M_gsn_e" name="Guanosine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N5O5</p>          </body>        </notes>      </species>      <species id="M_gthox_c" name="Oxidized glutathione" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H30N6O12S2</p>          </body>        </notes>      </species>      <species id="M_gthox_e" name="Oxidized glutathione" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H30N6O12S2</p>          </body>        </notes>      </species>      <species id="M_gthox_m" name="Oxidized glutathione" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H30N6O12S2</p>          </body>        </notes>      </species>      <species id="M_gthrd_c" name="Reduced glutathione" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16N3O6S</p>          </body>        </notes>      </species>      <species id="M_gthrd_e" name="Reduced glutathione" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16N3O6S</p>          </body>        </notes>      </species>      <species id="M_gthrd_m" name="Reduced glutathione" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16N3O6S</p>          </body>        </notes>      </species>      <species id="M_gthrd_r" name="Reduced glutathione" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16N3O6S</p>          </body>        </notes>      </species>      <species id="M_gtp_c" name="GTP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O14P3</p>          </body>        </notes>      </species>      <species id="M_gtp_e" name="GTP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O14P3</p>          </body>        </notes>      </species>      <species id="M_gtp_m" name="GTP" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O14P3</p>          </body>        </notes>      </species>      <species id="M_gtp_n" name="GTP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N5O14P3</p>          </body>        </notes>      </species>      <species id="M_gua_c" name="Guanine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H5N5O</p>          </body>        </notes>      </species>      <species id="M_gudac_c" name="Guanidinoacetate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7N3O2</p>          </body>        </notes>      </species>      <species id="M_guln_c" name="L-Gulonate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O7</p>          </body>        </notes>      </species>      <species id="M_guln_r" name="L-Gulonate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O7</p>          </body>        </notes>      </species>      <species id="M_h2co3_c" name="carbonic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2CO3</p>          </body>        </notes>      </species>      <species id="M_h2co3_m" name="carbonic acid" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2CO3</p>          </body>        </notes>      </species>      <species id="M_h2o2_c" name="Hydrogen peroxide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O2</p>          </body>        </notes>      </species>      <species id="M_h2o2_e" name="Hydrogen peroxide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O2</p>          </body>        </notes>      </species>      <species id="M_h2o2_m" name="Hydrogen peroxide" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O2</p>          </body>        </notes>      </species>      <species id="M_h2o2_n" name="Hydrogen peroxide" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O2</p>          </body>        </notes>      </species>      <species id="M_h2o2_x" name="Hydrogen peroxide" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O2</p>          </body>        </notes>      </species>      <species id="M_h2o_c" name="H2O" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O</p>          </body>        </notes>      </species>      <species id="M_h2o_e" name="H2O" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O</p>          </body>        </notes>      </species>      <species id="M_h2o_l" name="H2O" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O</p>          </body>        </notes>      </species>      <species id="M_h2o_m" name="H2O" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O</p>          </body>        </notes>      </species>      <species id="M_h2o_n" name="H2O" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O</p>          </body>        </notes>      </species>      <species id="M_h2o_r" name="H2O" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O</p>          </body>        </notes>      </species>      <species id="M_h2o_x" name="H2O" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H2O</p>          </body>        </notes>      </species>      <species id="M_hLkynr_c" name="3-Hydroxy-L-kynurenine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N2O4</p>          </body>        </notes>      </species>      <species id="M_h_c" name="H+" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H</p>          </body>        </notes>      </species>      <species id="M_h_e" name="H+" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H</p>          </body>        </notes>      </species>      <species id="M_h_l" name="H+" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H</p>          </body>        </notes>      </species>      <species id="M_h_m" name="H+" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H</p>          </body>        </notes>      </species>      <species id="M_h_n" name="H+" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H</p>          </body>        </notes>      </species>      <species id="M_h_r" name="H+" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H</p>          </body>        </notes>      </species>      <species id="M_h_x" name="H+" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H</p>          </body>        </notes>      </species>      <species id="M_ha_DASH_deg1_l" name="hyaluronan degradation product 1" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H33N2O16</p>          </body>        </notes>      </species>      <species id="M_ha_e" name="hyaluronan" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C28H40N2O22</p>          </body>        </notes>      </species>      <species id="M_ha_l" name="hyaluronan" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C28H40N2O22</p>          </body>        </notes>      </species>      <species id="M_ha_DASH_pre1_e" name="hyaluronan biosynthesis, precursor 1" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H20NO11</p>          </body>        </notes>      </species>      <species id="M_ha_DASH_pre1_l" name="hyaluronan biosynthesis, precursor 1" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H20NO11</p>          </body>        </notes>      </species>      <species id="M_hco3_c" name="Bicarbonate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CHO3</p>          </body>        </notes>      </species>      <species id="M_hco3_e" name="Bicarbonate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CHO3</p>          </body>        </notes>      </species>      <species id="M_hco3_m" name="Bicarbonate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CHO3</p>          </body>        </notes>      </species>      <species id="M_hcoumarin_c" name="hydroxy coumarin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H6O3</p>          </body>        </notes>      </species>      <species id="M_hcoumarin_e" name="hydroxy coumarin" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H6O3</p>          </body>        </notes>      </species>      <species id="M_hcys_DASH_DASH_DASH_L_c" name="L-Homocysteine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO2S</p>          </body>        </notes>      </species>      <species id="M_hdca_c" name="Hexadecanoate (n-C16:0)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H31O2</p>          </body>        </notes>      </species>      <species id="M_hdca_e" name="Hexadecanoate (n-C16:0)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H31O2</p>          </body>        </notes>      </species>      <species id="M_hdca_r" name="Hexadecanoate (n-C16:0)" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H31O2</p>          </body>        </notes>      </species>      <species id="M_hdcea_c" name="Hexadecenoate (n-C16:1)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H29O2</p>          </body>        </notes>      </species>      <species id="M_hdcea_e" name="Hexadecenoate (n-C16:1)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H29O2</p>          </body>        </notes>      </species>      <species id="M_hdcecrn_c" name="Hexadecenoyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H43NO4</p>          </body>        </notes>      </species>      <species id="M_hdcecrn_m" name="Hexadecenoyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H43NO4</p>          </body>        </notes>      </species>      <species id="M_hdcoa_c" name="Hexadecenoyl-CoA (n-C16:1CoA)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C37H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_hdcoa_m" name="Hexadecenoyl-CoA (n-C16:1CoA)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C37H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_hdd2coa_c" name="trans-Hexadec-2-enoyl-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C37H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_hdd2coa_m" name="trans-Hexadec-2-enoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C37H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_hdd2coa_x" name="trans-Hexadec-2-enoyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C37H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_hdd2crn_c" name="trans-Hexadec-2-enoyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H43NO4</p>          </body>        </notes>      </species>      <species id="M_hdd2crn_m" name="trans-Hexadec-2-enoyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H43NO4</p>          </body>        </notes>      </species>      <species id="M_hestratriol_c" name="4,17 dihydroxy estradiol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H24O3</p>          </body>        </notes>      </species>      <species id="M_hestratriol_e" name="4,17 dihydroxy estradiol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H24O3</p>          </body>        </notes>      </species>      <species id="M_hestratriol_r" name="4,17 dihydroxy estradiol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H24O3</p>          </body>        </notes>      </species>      <species id="M_hexc_c" name="hexacosanoate (n-C26:0)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H51O2</p>          </body>        </notes>      </species>      <species id="M_hexc_e" name="hexacosanoate (n-C26:0)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H51O2</p>          </body>        </notes>      </species>      <species id="M_hexccoa_c" name="Hexacosanoyl-CoA (n-C26:0CoA)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C47H82N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_hexccoa_x" name="Hexacosanoyl-CoA (n-C26:0CoA)" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C47H82N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_hgentis_c" name="Homogentisate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H7O4</p>          </body>        </notes>      </species>      <species id="M_his_DASH_DASH_DASH_L_c" name="L-Histidine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9N3O2</p>          </body>        </notes>      </species>      <species id="M_his_DASH_DASH_DASH_L_e" name="L-Histidine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9N3O2</p>          </body>        </notes>      </species>      <species id="M_hista_c" name="Histamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10N3</p>          </body>        </notes>      </species>      <species id="M_hista_e" name="Histamine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10N3</p>          </body>        </notes>      </species>      <species id="M_hmbil_c" name="Hydroxymethylbilane" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C40H38N4O17</p>          </body>        </notes>      </species>      <species id="M_hmgcoa_c" name="Hydroxymethylglutaryl-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H39N7O20P3S</p>          </body>        </notes>      </species>      <species id="M_hmgcoa_m" name="Hydroxymethylglutaryl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H39N7O20P3S</p>          </body>        </notes>      </species>      <species id="M_hmgcoa_x" name="Hydroxymethylglutaryl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H39N7O20P3S</p>          </body>        </notes>      </species>      <species id="M_hpdca_c" name="heptadecanoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H33O2</p>          </body>        </notes>      </species>      <species id="M_hpdca_e" name="heptadecanoate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H33O2</p>          </body>        </notes>      </species>      <species id="M_hpdcacoa_c" name="heptadecanoyl coa" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C38H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_hpdcacoa_m" name="heptadecanoyl coa" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C38H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_hpdcacrn_c" name="heptadecanoyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H47NO4</p>          </body>        </notes>      </species>      <species id="M_hpdcacrn_m" name="heptadecanoyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H47NO4</p>          </body>        </notes>      </species>      <species id="M_hpyr_c" name="Hydroxypyruvate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H3O4</p>          </body>        </notes>      </species>      <species id="M_hpyr_x" name="Hydroxypyruvate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H3O4</p>          </body>        </notes>      </species>      <species id="M_htaxol_c" name="hydroxylated taxol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C47H31NO15</p>          </body>        </notes>      </species>      <species id="M_htaxol_e" name="hydroxylated taxol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C47H31NO15</p>          </body>        </notes>      </species>      <species id="M_hxan_c" name="Hypoxanthine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4N4O</p>          </body>        </notes>      </species>      <species id="M_hxan_x" name="Hypoxanthine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4N4O</p>          </body>        </notes>      </species>      <species id="M_hyptaur_c" name="Hypotaurine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H6NO2S</p>          </body>        </notes>      </species>      <species id="M_ibcoa_m" name="Isobutyryl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H38N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_icit_c" name="Isocitrate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H5O7</p>          </body>        </notes>      </species>      <species id="M_icit_m" name="Isocitrate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H5O7</p>          </body>        </notes>      </species>      <species id="M_idp_c" name="IDP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O11P2</p>          </body>        </notes>      </species>      <species id="M_idp_e" name="IDP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O11P2</p>          </body>        </notes>      </species>      <species id="M_idp_n" name="IDP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O11P2</p>          </body>        </notes>      </species>      <species id="M_ile_DASH_DASH_DASH_L_c" name="L-Isoleucine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13NO2</p>          </body>        </notes>      </species>      <species id="M_ile_DASH_DASH_DASH_L_e" name="L-Isoleucine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13NO2</p>          </body>        </notes>      </species>      <species id="M_ile_DASH_DASH_DASH_L_m" name="L-Isoleucine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13NO2</p>          </body>        </notes>      </species>      <species id="M_imp_c" name="IMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O8P</p>          </body>        </notes>      </species>      <species id="M_imp_e" name="IMP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O8P</p>          </body>        </notes>      </species>      <species id="M_inost_c" name="myo-Inositol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_inost_e" name="myo-Inositol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_ins_c" name="Inosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N4O5</p>          </body>        </notes>      </species>      <species id="M_ins_e" name="Inosine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N4O5</p>          </body>        </notes>      </species>      <species id="M_ipdp_x" name="Isopentenyl diphosphate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9O7P2</p>          </body>        </notes>      </species>      <species id="M_itaccoa_m" name="Itaconyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H35N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_itacon_m" name="Itaconate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4O4</p>          </body>        </notes>      </species>      <species id="M_itp_c" name="ITP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O14P3</p>          </body>        </notes>      </species>      <species id="M_itp_n" name="ITP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O14P3</p>          </body>        </notes>      </species>      <species id="M_ivcoa_m" name="Isovaleryl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H40N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_k_c" name="potassium" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: K</p>          </body>        </notes>      </species>      <species id="M_k_e" name="potassium" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: K</p>          </body>        </notes>      </species>      <species id="M_kdn_c" name="2-keto-3-deoxy-D-glycero-D-galactononic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H15O9</p>          </body>        </notes>      </species>      <species id="M_kdnp_c" name="2-keto-3-deoxy-D-glycero-D-galactononic acid 9-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H14O12P</p>          </body>        </notes>      </species>      <species id="M_l2n2m2mn_l" name="de-Fuc, reducing GlcNAc removed, de-Sia form of PA6 (w/o peptide linkage)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C54H91N3O41</p>          </body>        </notes>      </species>      <species id="M_lac_DASH_DASH_DASH_D_c" name="D-Lactate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O3</p>          </body>        </notes>      </species>      <species id="M_lac_DASH_DASH_DASH_D_e" name="D-Lactate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O3</p>          </body>        </notes>      </species>      <species id="M_lac_DASH_DASH_DASH_L_c" name="L-Lactate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O3</p>          </body>        </notes>      </species>      <species id="M_lac_DASH_DASH_DASH_L_e" name="L-Lactate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O3</p>          </body>        </notes>      </species>      <species id="M_lac_DASH_DASH_DASH_L_m" name="L-Lactate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O3</p>          </body>        </notes>      </species>      <species id="M_lald_DASH_DASH_DASH_D_c" name="D-Lactaldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6O2</p>          </body>        </notes>      </species>      <species id="M_lald_DASH_DASH_DASH_L_c" name="L-Lactaldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6O2</p>          </body>        </notes>      </species>      <species id="M_lanost_r" name="Lanosterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C30H50O</p>          </body>        </notes>      </species>      <species id="M_leu_DASH_DASH_DASH_L_c" name="L-Leucine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13NO2</p>          </body>        </notes>      </species>      <species id="M_leu_DASH_DASH_DASH_L_e" name="L-Leucine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13NO2</p>          </body>        </notes>      </species>      <species id="M_leu_DASH_DASH_DASH_L_m" name="L-Leucine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H13NO2</p>          </body>        </notes>      </species>      <species id="M_leuktrA4_c" name="Leukotriene A4" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H29O3</p>          </body>        </notes>      </species>      <species id="M_leuktrA4_r" name="Leukotriene A4" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H29O3</p>          </body>        </notes>      </species>      <species id="M_leuktrC4_c" name="Leukotriene C4" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C30H45N3O9S</p>          </body>        </notes>      </species>      <species id="M_leuktrC4_e" name="Leukotriene C4" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C30H45N3O9S</p>          </body>        </notes>      </species>      <species id="M_leuktrC4_r" name="Leukotriene C4" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C30H45N3O9S</p>          </body>        </notes>      </species>      <species id="M_leuktrD4_c" name="Leukotriene D4" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H39N2O6S</p>          </body>        </notes>      </species>      <species id="M_leuktrD4_r" name="Leukotriene D4" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H39N2O6S</p>          </body>        </notes>      </species>      <species id="M_leuktrE4_c" name="leukotriene E4" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H36NO5S</p>          </body>        </notes>      </species>      <species id="M_leuktrF4_c" name="leukotriene F4" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C28H42N2O8S</p>          </body>        </notes>      </species>      <species id="M_lgnc_c" name="lignoceric acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H47O2</p>          </body>        </notes>      </species>      <species id="M_lgnc_e" name="lignoceric acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H47O2</p>          </body>        </notes>      </species>      <species id="M_lgnccoa_c" name="lignocericyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H78N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lgnccoa_x" name="lignocericyl coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H78N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lgt_DASH_DASH_DASH_S_c" name="(R)-S-Lactoylglutathione" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C13H20N3O8S</p>          </body>        </notes>      </species>      <species id="M_limnen_c" name="Limonene" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16</p>          </body>        </notes>      </species>      <species id="M_limnen_e" name="Limonene" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16</p>          </body>        </notes>      </species>      <species id="M_lneldc_c" name="linoelaidic acid (all trans C18:2)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H31O2</p>          </body>        </notes>      </species>      <species id="M_lneldc_e" name="linoelaidic acid (all trans C18:2)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H31O2</p>          </body>        </notes>      </species>      <species id="M_lneldccoa_c" name="linoelaidyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lneldccoa_m" name="linoelaidyl coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lneldccrn_c" name="Linoelaidyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H45NO4</p>          </body>        </notes>      </species>      <species id="M_lneldccrn_m" name="Linoelaidyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H45NO4</p>          </body>        </notes>      </species>      <species id="M_lnlc_c" name="linoleic acid (all cis C18:2) n-6" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H31O2</p>          </body>        </notes>      </species>      <species id="M_lnlc_e" name="linoleic acid (all cis C18:2) n-6" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H31O2</p>          </body>        </notes>      </species>      <species id="M_lnlccoa_c" name="linoleic coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lnlccoa_m" name="linoleic coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lnlccrn_c" name="Linoleyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H45NO4</p>          </body>        </notes>      </species>      <species id="M_lnlccrn_m" name="Linoleyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H45NO4</p>          </body>        </notes>      </species>      <species id="M_lnlnca_c" name="alpha-Linolenic acid, C18:3, n-3" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H29O2</p>          </body>        </notes>      </species>      <species id="M_lnlnca_e" name="alpha-Linolenic acid, C18:3, n-3" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H29O2</p>          </body>        </notes>      </species>      <species id="M_lnlncacoa_c" name="alpha-Linolenoyl-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lnlncacoa_m" name="alpha-Linolenoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lnlncacrn_c" name="alpha-linolenyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H43NO4</p>          </body>        </notes>      </species>      <species id="M_lnlncacrn_m" name="alpha-linolenyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H43NO4</p>          </body>        </notes>      </species>      <species id="M_lnlncg_c" name="gamma-linolenic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H29O2</p>          </body>        </notes>      </species>      <species id="M_lnlncg_e" name="gamma-linolenic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H29O2</p>          </body>        </notes>      </species>      <species id="M_lnlncgcoa_c" name="gamma-linolenoyl-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lnlncgcoa_m" name="gamma-linolenoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lnlncgcoa_x" name="gamma-linolenoyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_lnlncgcrn_c" name="gamma-linolenyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H43NO4</p>          </body>        </notes>      </species>      <species id="M_lnlncgcrn_m" name="gamma-linolenyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H43NO4</p>          </body>        </notes>      </species>      <species id="M_lpam_m" name="Lipoamide" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H15NOS2</p>          </body>        </notes>      </species>      <species id="M_lpchol_DASH_hs_c" name="lysophosphatidylcholine (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H19NO5PFULLRCO2</p>          </body>        </notes>      </species>      <species id="M_lpchol_DASH_hs_e" name="lysophosphatidylcholine (homo sapiens)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H19NO5PFULLRCO2</p>          </body>        </notes>      </species>      <species id="M_lpro_m" name="Lipoylprotein" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: S2X</p>          </body>        </notes>      </species>      <species id="M_lthstrl_r" name="5alpha-Cholest-7-en-3beta-ol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O</p>          </body>        </notes>      </species>      <species id="M_lys_DASH_DASH_DASH_L_c" name="L-Lysine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H15N2O2</p>          </body>        </notes>      </species>      <species id="M_lys_DASH_DASH_DASH_L_e" name="L-Lysine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H15N2O2</p>          </body>        </notes>      </species>      <species id="M_lys_DASH_DASH_DASH_L_m" name="L-Lysine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H15N2O2</p>          </body>        </notes>      </species>      <species id="M_lys_DASH_DASH_DASH_L_n" name="L-Lysine" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H15N2O2</p>          </body>        </notes>      </species>      <species id="M_lys_DASH_DASH_DASH_L_x" name="L-Lysine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H15N2O2</p>          </body>        </notes>      </species>      <species id="M_m2mn_l" name="(alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H45NO21</p>          </body>        </notes>      </species>      <species id="M_mag_DASH_hs_c" name="monoacylglycerol 2 (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7O2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_mag_DASH_hs_e" name="monoacylglycerol 2 (homo sapiens)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7O2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_mal_DASH_DASH_DASH_L_c" name="L-Malate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H4O5</p>          </body>        </notes>      </species>      <species id="M_mal_DASH_DASH_DASH_L_m" name="L-Malate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H4O5</p>          </body>        </notes>      </species>      <species id="M_malcoa_c" name="Malonyl-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H33N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_malcoa_m" name="Malonyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H33N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_malt_c" name="Maltose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H22O11</p>          </body>        </notes>      </species>      <species id="M_malt_e" name="Maltose" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H22O11</p>          </body>        </notes>      </species>      <species id="M_man6p_c" name="D-Mannose 6-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_man_c" name="D-Mannose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_man_e" name="D-Mannose" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_man_l" name="D-Mannose" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_meoh_c" name="Methanol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH4O1</p>          </body>        </notes>      </species>      <species id="M_mercplac_c" name="3-Mercaptolactate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O3S</p>          </body>        </notes>      </species>      <species id="M_mercplaccys_c" name="3-mercaptolactate-cysteine disulfide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10O5S2N</p>          </body>        </notes>      </species>      <species id="M_mercplaccys_e" name="3-mercaptolactate-cysteine disulfide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10O5S2N</p>          </body>        </notes>      </species>      <species id="M_mercppyr_c" name="Mercaptopyruvate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H3O3S</p>          </body>        </notes>      </species>      <species id="M_mescoa_m" name="Mesaconyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H35N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_mescon_m" name="Mesaconate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4O4</p>          </body>        </notes>      </species>      <species id="M_met_DASH_DASH_DASH_L_c" name="L-Methionine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H11NO2S</p>          </body>        </notes>      </species>      <species id="M_met_DASH_DASH_DASH_L_e" name="L-Methionine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H11NO2S</p>          </body>        </notes>      </species>      <species id="M_methf_c" name="5,10-Methenyltetrahydrofolate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H20N7O6</p>          </body>        </notes>      </species>      <species id="M_methf_m" name="5,10-Methenyltetrahydrofolate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H20N7O6</p>          </body>        </notes>      </species>      <species id="M_mev_DASH_DASH_DASH_R_x" name="(R)-Mevalonate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O4</p>          </body>        </notes>      </species>      <species id="M_mhista_c" name="N-Methylhistamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12N3</p>          </body>        </notes>      </species>      <species id="M_mi1345p_c" name="1D-myo-Inositol 1,3,4,5-tetrakisphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H8O18P4</p>          </body>        </notes>      </species>      <species id="M_mi134p_c" name="1D-myo-Inositol 1,3,4-trisphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O15P3</p>          </body>        </notes>      </species>      <species id="M_mi145p_c" name="1D-myo-Inositol 1,4,5-trisphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H9O15P3</p>          </body>        </notes>      </species>      <species id="M_mi14p_c" name="1D-myo-Inositol 1,4-bisphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10O12P2</p>          </body>        </notes>      </species>      <species id="M_mi14p_n" name="1D-myo-Inositol 1,4-bisphosphate" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10O12P2</p>          </body>        </notes>      </species>      <species id="M_mi1p_DASH_DASH_DASH_D_c" name="1D-myo-Inositol 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_mi1p_DASH_DASH_DASH_D_n" name="1D-myo-Inositol 1-phosphate" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_mi34p_c" name="1D-myo-Inositol 3,4-bisphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H10O12P2</p>          </body>        </notes>      </species>      <species id="M_mi3p_DASH_DASH_DASH_D_c" name="1D-myo-Inositol 3-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_mi4p_DASH_DASH_DASH_D_c" name="1D-myo-Inositol 4-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_mlthf_c" name="5,10-Methylenetetrahydrofolate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H21N7O6</p>          </body>        </notes>      </species>      <species id="M_mlthf_m" name="5,10-Methylenetetrahydrofolate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H21N7O6</p>          </body>        </notes>      </species>      <species id="M_mma_c" name="Methylamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C1H6N</p>          </body>        </notes>      </species>      <species id="M_mmcoa_DASH_DASH_DASH_R_m" name="(R)-Methylmalonyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H35N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_mmcoa_DASH_DASH_DASH_S_m" name="(S)-Methylmalonyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H35N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_mn_l" name="beta-1,4-mannose-N-acetylglucosamine" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H25NO11</p>          </body>        </notes>      </species>      <species id="M_msa_m" name="Malonate semialdehyde" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H3O3</p>          </body>        </notes>      </species>      <species id="M_mthgxl_c" name="Methylglyoxal" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H4O2</p>          </body>        </notes>      </species>      <species id="M_n2m2mn_l" name="de-Fuc, reducing GlcNAc removed, de-Sia, de-Gal form of PA6 (w/o peptide linkage)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C42H71N3O31</p>          </body>        </notes>      </species>      <species id="M_n2m2nm_l" name="n2m2nmasn (w/o peptide linkage)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C58H97N5O41</p>          </body>        </notes>      </species>      <species id="M_n2m2nmasn_e" name="N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C58H96N5O40X</p>          </body>        </notes>      </species>      <species id="M_n2m2nmasn_l" name="N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C58H96N5O40X</p>          </body>        </notes>      </species>      <species id="M_n2m2nmn_l" name="reducing GlcNAc removed form of n2m2nmasn (w/o peptide)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C50H84N4O36</p>          </body>        </notes>      </species>      <species id="M_na1_c" name="Sodium" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Na</p>          </body>        </notes>      </species>      <species id="M_na1_e" name="Sodium" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Na</p>          </body>        </notes>      </species>      <species id="M_na1_x" name="Sodium" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: Na</p>          </body>        </notes>      </species>      <species id="M_nac_c" name="Nicotinate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H4NO2</p>          </body>        </notes>      </species>      <species id="M_nac_e" name="Nicotinate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H4NO2</p>          </body>        </notes>      </species>      <species id="M_nad_c" name="Nicotinamide adenine dinucleotide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H26N7O14P2</p>          </body>        </notes>      </species>      <species id="M_nad_m" name="Nicotinamide adenine dinucleotide" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H26N7O14P2</p>          </body>        </notes>      </species>      <species id="M_nad_n" name="Nicotinamide adenine dinucleotide" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H26N7O14P2</p>          </body>        </notes>      </species>      <species id="M_nad_r" name="Nicotinamide adenine dinucleotide" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H26N7O14P2</p>          </body>        </notes>      </species>      <species id="M_nad_x" name="Nicotinamide adenine dinucleotide" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H26N7O14P2</p>          </body>        </notes>      </species>      <species id="M_nadh_c" name="Nicotinamide adenine dinucleotide - reduced" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H27N7O14P2</p>          </body>        </notes>      </species>      <species id="M_nadh_m" name="Nicotinamide adenine dinucleotide - reduced" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H27N7O14P2</p>          </body>        </notes>      </species>      <species id="M_nadh_r" name="Nicotinamide adenine dinucleotide - reduced" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H27N7O14P2</p>          </body>        </notes>      </species>      <species id="M_nadh_x" name="Nicotinamide adenine dinucleotide - reduced" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H27N7O14P2</p>          </body>        </notes>      </species>      <species id="M_nadp_c" name="Nicotinamide adenine dinucleotide phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H25N7O17P3</p>          </body>        </notes>      </species>      <species id="M_nadp_m" name="Nicotinamide adenine dinucleotide phosphate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H25N7O17P3</p>          </body>        </notes>      </species>      <species id="M_nadp_r" name="Nicotinamide adenine dinucleotide phosphate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H25N7O17P3</p>          </body>        </notes>      </species>      <species id="M_nadp_x" name="Nicotinamide adenine dinucleotide phosphate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H25N7O17P3</p>          </body>        </notes>      </species>      <species id="M_nadph_c" name="Nicotinamide adenine dinucleotide phosphate - reduced" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H26N7O17P3</p>          </body>        </notes>      </species>      <species id="M_nadph_m" name="Nicotinamide adenine dinucleotide phosphate - reduced" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H26N7O17P3</p>          </body>        </notes>      </species>      <species id="M_nadph_r" name="Nicotinamide adenine dinucleotide phosphate - reduced" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H26N7O17P3</p>          </body>        </notes>      </species>      <species id="M_nadph_x" name="Nicotinamide adenine dinucleotide phosphate - reduced" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H26N7O17P3</p>          </body>        </notes>      </species>      <species id="M_ncam_c" name="Nicotinamide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H6N2O</p>          </body>        </notes>      </species>      <species id="M_nh4_c" name="Ammonium" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H4N</p>          </body>        </notes>      </species>      <species id="M_nh4_e" name="Ammonium" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H4N</p>          </body>        </notes>      </species>      <species id="M_nh4_m" name="Ammonium" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H4N</p>          </body>        </notes>      </species>      <species id="M_nh4_x" name="Ammonium" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: H4N</p>          </body>        </notes>      </species>      <species id="M_nicrns_c" name="Nicotinate D-ribonucleoside" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H13NO6</p>          </body>        </notes>      </species>      <species id="M_nicrnt_c" name="Nicotinate D-ribonucleotide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H12NO9P</p>          </body>        </notes>      </species>      <species id="M_nicrnt_n" name="Nicotinate D-ribonucleotide" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H12NO9P</p>          </body>        </notes>      </species>      <species id="M_nmn_c" name="NMN" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H14N2O8P</p>          </body>        </notes>      </species>      <species id="M_nmn_n" name="NMN" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H14N2O8P</p>          </body>        </notes>      </species>      <species id="M_no_c" name="Nitric oxide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: NO</p>          </body>        </notes>      </species>      <species id="M_no_e" name="Nitric oxide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: NO</p>          </body>        </notes>      </species>      <species id="M_nrpphr_c" name="Norepinephrine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H12NO3</p>          </body>        </notes>      </species>      <species id="M_nrpphr_e" name="Norepinephrine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H12NO3</p>          </body>        </notes>      </species>      <species id="M_nrpphrsf_c" name="Sulfate derivative of norepinephrine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H11NO6S</p>          </body>        </notes>      </species>      <species id="M_nrpphrsf_e" name="Sulfate derivative of norepinephrine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H11NO6S</p>          </body>        </notes>      </species>      <species id="M_nrvnc_c" name="nervonic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H45O2</p>          </body>        </notes>      </species>      <species id="M_nrvnc_e" name="nervonic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H45O2</p>          </body>        </notes>      </species>      <species id="M_nrvnccoa_c" name="nervonyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H76N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_nrvnccoa_x" name="nervonyl coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H76N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_nwharg_c" name="N-(omega)-Hydroxyarginine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H15N4O3</p>          </body>        </notes>      </species>      <species id="M_o2_c" name="O2" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O2</p>          </body>        </notes>      </species>      <species id="M_o2_m" name="O2" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O2</p>          </body>        </notes>      </species>      <species id="M_o2_n" name="O2" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O2</p>          </body>        </notes>      </species>      <species id="M_o2_r" name="O2" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O2</p>          </body>        </notes>      </species>      <species id="M_o2_x" name="O2" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O2</p>          </body>        </notes>      </species>      <species id="M_o2s_c" name="Superoxide anion" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O2</p>          </body>        </notes>      </species>      <species id="M_o2s_e" name="Superoxide anion" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O2</p>          </body>        </notes>      </species>      <species id="M_o2s_m" name="Superoxide anion" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O2</p>          </body>        </notes>      </species>      <species id="M_o2s_n" name="Superoxide anion" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O2</p>          </body>        </notes>      </species>      <species id="M_o2s_x" name="Superoxide anion" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O2</p>          </body>        </notes>      </species>      <species id="M_oaa_c" name="Oxaloacetate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H2O5</p>          </body>        </notes>      </species>      <species id="M_oaa_m" name="Oxaloacetate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H2O5</p>          </body>        </notes>      </species>      <species id="M_occoa_c" name="Octanoyl-CoA (n-C8:0CoA)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H46N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_occoa_m" name="Octanoyl-CoA (n-C8:0CoA)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H46N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_occoa_x" name="Octanoyl-CoA (n-C8:0CoA)" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H46N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_ocdca_c" name="octadecanoate (n-C18:0)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H35O2</p>          </body>        </notes>      </species>      <species id="M_ocdca_e" name="octadecanoate (n-C18:0)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H35O2</p>          </body>        </notes>      </species>      <species id="M_ocdcea_c" name="octadecenoate (n-C18:1)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H33O2</p>          </body>        </notes>      </species>      <species id="M_ocdcea_e" name="octadecenoate (n-C18:1)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H33O2</p>          </body>        </notes>      </species>      <species id="M_octa_c" name="octanoate (n-C8:0)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H15O2</p>          </body>        </notes>      </species>      <species id="M_octa_e" name="octanoate (n-C8:0)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H15O2</p>          </body>        </notes>      </species>      <species id="M_od2coa_c" name="trans-Octadec-2-enoyl-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_od2coa_m" name="trans-Octadec-2-enoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_odecoa_c" name="Octadecenoyl-CoA (n-C18:1CoA)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_odecoa_m" name="Octadecenoyl-CoA (n-C18:1CoA)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_odecoa_x" name="Octadecenoyl-CoA (n-C18:1CoA)" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_odecrn_c" name="octadecenoyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H47NO4</p>          </body>        </notes>      </species>      <species id="M_odecrn_m" name="octadecenoyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H47NO4</p>          </body>        </notes>      </species>      <species id="M_oh1_c" name="hydroxide ion" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO</p>          </body>        </notes>      </species>      <species id="M_oh1_e" name="hydroxide ion" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO</p>          </body>        </notes>      </species>      <species id="M_omeprazole_c" name="omeprazole" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H19N3O3S</p>          </body>        </notes>      </species>      <species id="M_omeprazole_e" name="omeprazole" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H19N3O3S</p>          </body>        </notes>      </species>      <species id="M_orn_c" name="Ornithine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H13N2O2</p>          </body>        </notes>      </species>      <species id="M_orn_e" name="Ornithine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H13N2O2</p>          </body>        </notes>      </species>      <species id="M_orn_m" name="Ornithine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H13N2O2</p>          </body>        </notes>      </species>      <species id="M_orot5p_c" name="Orotidine 5&apos;-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H10N2O11P</p>          </body>        </notes>      </species>      <species id="M_orot_c" name="Orotate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H3N2O4</p>          </body>        </notes>      </species>      <species id="M_oxa_c" name="Oxalate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2O4</p>          </body>        </notes>      </species>      <species id="M_oxa_e" name="Oxalate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2O4</p>          </body>        </notes>      </species>      <species id="M_oxa_x" name="Oxalate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2O4</p>          </body>        </notes>      </species>      <species id="M_pa_DASH_hs_c" name="phosphatidic acid (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pa_DASH_hs_m" name="phosphatidic acid (homo sapiens)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pa_DASH_hs_n" name="phosphatidic acid (homo sapiens)" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pa_DASH_hs_r" name="phosphatidic acid (homo sapiens)" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pac_c" name="Phenylacetic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H7O2</p>          </body>        </notes>      </species>      <species id="M_pacald_c" name="Phenylacetaldehyde" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H8O</p>          </body>        </notes>      </species>      <species id="M_paf_DASH_hs_e" name="1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H23O4NPFULLRCO2</p>          </body>        </notes>      </species>      <species id="M_pail345p_DASH_hs_c" name="phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H13O18P4FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail345p_DASH_hs_n" name="phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H13O18P4FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail34p_DASH_hs_c" name="phosphatidylinositol-3,4-bisphosphate (Homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H14O15P3FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail35p_DASH_hs_c" name="phosphatidylinositol-3,5-bisphosphate (Homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H14O15P3FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail3p_DASH_hs_c" name="1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H15O12P2FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail45p_DASH_hs_c" name="phosphatidylinositol 4,5-bisphosphate (Homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H14O15P3FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail45p_DASH_hs_n" name="phosphatidylinositol 4,5-bisphosphate (Homo sapiens)" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H14O15P3FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail4p_DASH_hs_c" name="1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H15O12P2FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail4p_DASH_hs_n" name="1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H15O12P2FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail5p_DASH_hs_c" name="1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H15O12P2FULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail_DASH_hs_c" name="phosphatidylinositol (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H16O9PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pail_DASH_hs_n" name="phosphatidylinositol (homo sapiens)" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H16O9PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pan4p_c" name="Pantetheine 4&apos;-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H21N2O7PS</p>          </body>        </notes>      </species>      <species id="M_pap_c" name="Adenosine 3&apos;,5&apos;-bisphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N5O10P2</p>          </body>        </notes>      </species>      <species id="M_paps_c" name="3&apos;-Phosphoadenylyl sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N5O13P2S</p>          </body>        </notes>      </species>      <species id="M_pchol_DASH_hs_c" name="Phosphatidylcholine (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H18NO4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pchol_DASH_hs_e" name="Phosphatidylcholine (homo sapiens)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H18NO4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pchol_DASH_hs_m" name="Phosphatidylcholine (homo sapiens)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H18NO4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pchol_DASH_hs_r" name="Phosphatidylcholine (homo sapiens)" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H18NO4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pcreat_c" name="Phosphocreatine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9N3O5P</p>          </body>        </notes>      </species>      <species id="M_pcreat_m" name="Phosphocreatine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9N3O5P</p>          </body>        </notes>      </species>      <species id="M_pcrn_c" name="propionyl-carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H19NO4</p>          </body>        </notes>      </species>      <species id="M_pcrn_m" name="propionyl-carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H19NO4</p>          </body>        </notes>      </species>      <species id="M_pcrn_x" name="propionyl-carnitine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H19NO4</p>          </body>        </notes>      </species>      <species id="M_pd3_c" name="Previtamin D3" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O</p>          </body>        </notes>      </species>      <species id="M_pdx5p_c" name="Pyridoxine 5&apos;-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H10NO6P</p>          </body>        </notes>      </species>      <species id="M_pe_DASH_hs_c" name="phosphatidylethanolamine (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H12NO4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pe_DASH_hs_e" name="phosphatidylethanolamine (homo sapiens)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H12NO4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pe_DASH_hs_m" name="phosphatidylethanolamine (homo sapiens)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H12NO4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pe_DASH_hs_r" name="phosphatidylethanolamine (homo sapiens)" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H12NO4PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_peamn_c" name="Phenethylamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H12N</p>          </body>        </notes>      </species>      <species id="M_pep_c" name="Phosphoenolpyruvate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H2O6P</p>          </body>        </notes>      </species>      <species id="M_pep_m" name="Phosphoenolpyruvate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H2O6P</p>          </body>        </notes>      </species>      <species id="M_perillyl_c" name="Perillyl alcohol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16O</p>          </body>        </notes>      </species>      <species id="M_perillyl_e" name="Perillyl alcohol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H16O</p>          </body>        </notes>      </species>      <species id="M_phaccoa_c" name="Phenylacetyl-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C29H38N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_phe_DASH_DASH_DASH_L_c" name="L-Phenylalanine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11NO2</p>          </body>        </notes>      </species>      <species id="M_phe_DASH_DASH_DASH_L_e" name="L-Phenylalanine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11NO2</p>          </body>        </notes>      </species>      <species id="M_pheacgln_c" name="alpha-N-Phenylacetyl-L-glutamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C13H16N2O4</p>          </body>        </notes>      </species>      <species id="M_pheacgln_e" name="alpha-N-Phenylacetyl-L-glutamine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C13H16N2O4</p>          </body>        </notes>      </species>      <species id="M_pheme_c" name="Protoheme" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C34H30FeN4O4</p>          </body>        </notes>      </species>      <species id="M_pheme_m" name="Protoheme" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C34H30FeN4O4</p>          </body>        </notes>      </species>      <species id="M_pi_c" name="Phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO4P</p>          </body>        </notes>      </species>      <species id="M_pi_e" name="Phosphate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO4P</p>          </body>        </notes>      </species>      <species id="M_pi_m" name="Phosphate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO4P</p>          </body>        </notes>      </species>      <species id="M_pi_n" name="Phosphate" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO4P</p>          </body>        </notes>      </species>      <species id="M_pi_r" name="Phosphate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO4P</p>          </body>        </notes>      </species>      <species id="M_pi_x" name="Phosphate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO4P</p>          </body>        </notes>      </species>      <species id="M_pmtcoa_c" name="Palmitoyl-CoA (n-C16:0CoA)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C37H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_pmtcoa_m" name="Palmitoyl-CoA (n-C16:0CoA)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C37H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_pmtcoa_x" name="Palmitoyl-CoA (n-C16:0CoA)" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C37H62N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_pmtcrn_c" name="L-Palmitoylcarnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H45NO4</p>          </body>        </notes>      </species>      <species id="M_pmtcrn_m" name="L-Palmitoylcarnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H45NO4</p>          </body>        </notes>      </species>      <species id="M_pnto_DASH_DASH_DASH_R_c" name="(R)-Pantothenate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H16NO5</p>          </body>        </notes>      </species>      <species id="M_ppa_c" name="Propionate (n-C3:0)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O2</p>          </body>        </notes>      </species>      <species id="M_ppa_e" name="Propionate (n-C3:0)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5O2</p>          </body>        </notes>      </species>      <species id="M_ppbng_c" name="Porphobilinogen" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O4</p>          </body>        </notes>      </species>      <species id="M_ppcoa_c" name="Propanoyl-CoA" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H36N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_ppcoa_m" name="Propanoyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H36N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_ppcoa_x" name="Propanoyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H36N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_ppi_c" name="Diphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO7P2</p>          </body>        </notes>      </species>      <species id="M_ppi_m" name="Diphosphate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO7P2</p>          </body>        </notes>      </species>      <species id="M_ppi_n" name="Diphosphate" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO7P2</p>          </body>        </notes>      </species>      <species id="M_ppi_r" name="Diphosphate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO7P2</p>          </body>        </notes>      </species>      <species id="M_ppi_x" name="Diphosphate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: HO7P2</p>          </body>        </notes>      </species>      <species id="M_ppp9_m" name="Protoporphyrin" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C34H32N4O4</p>          </body>        </notes>      </species>      <species id="M_pppg9_c" name="Protoporphyrinogen IX" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C34H38N4O4</p>          </body>        </notes>      </species>      <species id="M_pppg9_m" name="Protoporphyrinogen IX" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C34H38N4O4</p>          </body>        </notes>      </species>      <species id="M_pram_c" name="5-Phospho-beta-D-ribosylamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H11NO7P</p>          </body>        </notes>      </species>      <species id="M_prgnlone_c" name="Pregnenolone" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H32O2</p>          </body>        </notes>      </species>      <species id="M_prgnlones_c" name="pregnenolone sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H31O5S</p>          </body>        </notes>      </species>      <species id="M_prist_c" name="pristanic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H37O2</p>          </body>        </notes>      </species>      <species id="M_prist_x" name="pristanic acid" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H37O2</p>          </body>        </notes>      </species>      <species id="M_pristcoa_c" name="pristanoyl coa" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C40H68N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_pristcoa_x" name="pristanoyl coa" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C40H68N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_pro_DASH_DASH_DASH_L_c" name="L-Proline" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9NO2</p>          </body>        </notes>      </species>      <species id="M_pro_DASH_DASH_DASH_L_e" name="L-Proline" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9NO2</p>          </body>        </notes>      </species>      <species id="M_pro_DASH_DASH_DASH_L_m" name="L-Proline" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9NO2</p>          </body>        </notes>      </species>      <species id="M_prostge2_c" name="Prostaglandin E2" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H31O5</p>          </body>        </notes>      </species>      <species id="M_prostge2_e" name="Prostaglandin E2" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H31O5</p>          </body>        </notes>      </species>      <species id="M_prostgf2_c" name="Prostaglandin F2alpha" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H33O5</p>          </body>        </notes>      </species>      <species id="M_prostgf2_e" name="Prostaglandin F2alpha" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H33O5</p>          </body>        </notes>      </species>      <species id="M_prpp_c" name="5-Phospho-alpha-D-ribose 1-diphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H8O14P3</p>          </body>        </notes>      </species>      <species id="M_ps_DASH_hs_c" name="phosphatidylserine (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11NO6PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_ps_DASH_hs_e" name="phosphatidylserine (homo sapiens)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11NO6PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_ps_DASH_hs_m" name="phosphatidylserine (homo sapiens)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11NO6PFULLRCO2FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_pser_DASH_DASH_DASH_L_c" name="O-Phospho-L-serine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H6NO6P</p>          </body>        </notes>      </species>      <species id="M_ptdca_c" name="pentadecanoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H29O2</p>          </body>        </notes>      </species>      <species id="M_ptdca_e" name="pentadecanoate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H29O2</p>          </body>        </notes>      </species>      <species id="M_ptdcacoa_c" name="pentadecanoyl Coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C36H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_ptdcacoa_m" name="pentadecanoyl Coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C36H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_ptdcacrn_c" name="pendtadenoyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H43NO4</p>          </body>        </notes>      </species>      <species id="M_ptdcacrn_m" name="pendtadenoyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C22H43NO4</p>          </body>        </notes>      </species>      <species id="M_ptrc_c" name="Putrescine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H14N2</p>          </body>        </notes>      </species>      <species id="M_ptth_c" name="Pantetheine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H22N2O4S</p>          </body>        </notes>      </species>      <species id="M_pyam5p_c" name="Pyridoxamine 5&apos;-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H12N2O5P</p>          </body>        </notes>      </species>      <species id="M_pydam_c" name="Pyridoxamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H13N2O2</p>          </body>        </notes>      </species>      <species id="M_pydam_e" name="Pyridoxamine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H13N2O2</p>          </body>        </notes>      </species>      <species id="M_pydx5p_c" name="Pyridoxal 5&apos;-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H8NO6P</p>          </body>        </notes>      </species>      <species id="M_pydx_c" name="Pyridoxal" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H9NO3</p>          </body>        </notes>      </species>      <species id="M_pydxn_c" name="Pyridoxine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H11NO3</p>          </body>        </notes>      </species>      <species id="M_pydxn_e" name="Pyridoxine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H11NO3</p>          </body>        </notes>      </species>      <species id="M_pyr_c" name="Pyruvate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H3O3</p>          </body>        </notes>      </species>      <species id="M_pyr_e" name="Pyruvate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H3O3</p>          </body>        </notes>      </species>      <species id="M_pyr_m" name="Pyruvate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H3O3</p>          </body>        </notes>      </species>      <species id="M_pyr_x" name="Pyruvate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H3O3</p>          </body>        </notes>      </species>      <species id="M_q10_m" name="Ubiquinone-10" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C59H90O4</p>          </body>        </notes>      </species>      <species id="M_q10h2_m" name="Ubiquinol-10" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C59H92O4</p>          </body>        </notes>      </species>      <species id="M_quln_c" name="Quinolinate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H3NO4</p>          </body>        </notes>      </species>      <species id="M_r1p_c" name="alpha-D-Ribose 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9O8P</p>          </body>        </notes>      </species>      <species id="M_r5p_c" name="alpha-D-Ribose 5-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9O8P</p>          </body>        </notes>      </species>      <species id="M_retinal_DASH_DASH_DASH_11_DASH_DASH_DASH_cis_c" name="cis-11-retinal" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H28O</p>          </body>        </notes>      </species>      <species id="M_retinal_DASH_DASH_DASH_cis_DASH_DASH_DASH_9_c" name="cis-9-retinal" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H28O</p>          </body>        </notes>      </species>      <species id="M_retinal_c" name="Retinal" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H28O</p>          </body>        </notes>      </species>      <species id="M_retinol_DASH_DASH_DASH_9_DASH_DASH_DASH_cis_c" name="9-cis-retinol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H30O</p>          </body>        </notes>      </species>      <species id="M_retinol_DASH_DASH_DASH_cis_DASH_DASH_DASH_11_c" name="cis-11-retinol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H30O</p>          </body>        </notes>      </species>      <species id="M_retinol_c" name="Retinol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H30O</p>          </body>        </notes>      </species>      <species id="M_retn_c" name="Retinoate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H27O2</p>          </body>        </notes>      </species>      <species id="M_retn_e" name="Retinoate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H27O2</p>          </body>        </notes>      </species>      <species id="M_retn_r" name="Retinoate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H27O2</p>          </body>        </notes>      </species>      <species id="M_retnglc_c" name="retinoyl glucuronide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H35O8</p>          </body>        </notes>      </species>      <species id="M_retnglc_e" name="retinoyl glucuronide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H35O8</p>          </body>        </notes>      </species>      <species id="M_retnglc_r" name="retinoyl glucuronide" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H35O8</p>          </body>        </notes>      </species>      <species id="M_rib_DASH_DASH_DASH_D_c" name="D-Ribose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10O5</p>          </body>        </notes>      </species>      <species id="M_rib_DASH_DASH_DASH_D_e" name="D-Ribose" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10O5</p>          </body>        </notes>      </species>      <species id="M_ribflv_c" name="Riboflavin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H20N4O6</p>          </body>        </notes>      </species>      <species id="M_rnam_c" name="N-Ribosylnicotinamide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H15N2O5</p>          </body>        </notes>      </species>      <species id="M_ru5p_DASH_DASH_DASH_D_c" name="D-Ribulose 5-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9O8P</p>          </body>        </notes>      </species>      <species id="M_s2l2fn2m2masn_e" name="PA6" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C90H145N6O65X</p>          </body>        </notes>      </species>      <species id="M_s2l2n2m2m_l" name="de-Fuc form of PA6 (w/o peptide linkage)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C84H136N6O62</p>          </body>        </notes>      </species>      <species id="M_s2l2n2m2masn_e" name="de-Fuc form of PA6" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C84H135N6O61X</p>          </body>        </notes>      </species>      <species id="M_s2l2n2m2masn_l" name="de-Fuc form of PA6" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C84H135N6O61X</p>          </body>        </notes>      </species>      <species id="M_s2l2n2m2mn_l" name="de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C76H123N5O57</p>          </body>        </notes>      </species>      <species id="M_s7p_c" name="Sedoheptulose 7-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H13O10P</p>          </body>        </notes>      </species>      <species id="M_saccrp_DASH_DASH_DASH_L_m" name="L-Saccharopine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H19N2O6</p>          </body>        </notes>      </species>      <species id="M_sarcs_c" name="Sarcosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2</p>          </body>        </notes>      </species>      <species id="M_sarcs_m" name="Sarcosine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO2</p>          </body>        </notes>      </species>      <species id="M_sbt_DASH_DASH_DASH_D_c" name="D-Sorbitol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H14O6</p>          </body>        </notes>      </species>      <species id="M_ser_DASH_DASH_DASH_L_c" name="L-Serine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO3</p>          </body>        </notes>      </species>      <species id="M_ser_DASH_DASH_DASH_L_e" name="L-Serine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO3</p>          </body>        </notes>      </species>      <species id="M_ser_DASH_DASH_DASH_L_x" name="L-Serine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H7NO3</p>          </body>        </notes>      </species>      <species id="M_sl_DASH_DASH_DASH_L_c" name="L-sulfolactate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H4O6S</p>          </body>        </notes>      </species>      <species id="M_sl_DASH_DASH_DASH_L_e" name="L-sulfolactate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H4O6S</p>          </body>        </notes>      </species>      <species id="M_so3_c" name="Sulfite" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O3S</p>          </body>        </notes>      </species>      <species id="M_so3_m" name="Sulfite" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O3S</p>          </body>        </notes>      </species>      <species id="M_so4_c" name="Sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O4S</p>          </body>        </notes>      </species>      <species id="M_so4_e" name="Sulfate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O4S</p>          </body>        </notes>      </species>      <species id="M_sph1p_c" name="Sphinganine 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H39NO5P</p>          </body>        </notes>      </species>      <species id="M_sph1p_r" name="Sphinganine 1-phosphate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H39NO5P</p>          </body>        </notes>      </species>      <species id="M_sphgn_c" name="Sphinganine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H40NO2</p>          </body>        </notes>      </species>      <species id="M_sphgn_r" name="Sphinganine" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H40NO2</p>          </body>        </notes>      </species>      <species id="M_sphings_c" name="Sphingosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H38NO2</p>          </body>        </notes>      </species>      <species id="M_sphings_l" name="Sphingosine" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H38NO2</p>          </body>        </notes>      </species>      <species id="M_sphings_r" name="Sphingosine" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H38NO2</p>          </body>        </notes>      </species>      <species id="M_sphmyln_DASH_hs_c" name="sphingomyelin (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H48N2O5PFULLRCO</p>          </body>        </notes>      </species>      <species id="M_sphmyln_DASH_hs_l" name="sphingomyelin (homo sapiens)" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C23H48N2O5PFULLRCO</p>          </body>        </notes>      </species>      <species id="M_sphs1p_c" name="Sphingosine 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H37NO5P</p>          </body>        </notes>      </species>      <species id="M_sphs1p_r" name="Sphingosine 1-phosphate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H37NO5P</p>          </body>        </notes>      </species>      <species id="M_spmd_c" name="Spermidine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C7H22N3</p>          </body>        </notes>      </species>      <species id="M_sprm_c" name="Spermine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H30N4</p>          </body>        </notes>      </species>      <species id="M_sql_r" name="Squalene" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C30H50</p>          </body>        </notes>      </species>      <species id="M_srtn_c" name="Serotonin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O</p>          </body>        </notes>      </species>      <species id="M_srtn_e" name="Serotonin" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H13N2O</p>          </body>        </notes>      </species>      <species id="M_stcoa_c" name="Stearoyl-CoA (n-C18:0CoA)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H66N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_stcoa_m" name="Stearoyl-CoA (n-C18:0CoA)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H66N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_stcoa_x" name="Stearoyl-CoA (n-C18:0CoA)" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H66N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_stcrn_c" name="stearoylcarnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H49NO4</p>          </body>        </notes>      </species>      <species id="M_stcrn_m" name="stearoylcarnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H49NO4</p>          </body>        </notes>      </species>      <species id="M_strch1_e" name="starch, structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]})" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C66H112O56</p>          </body>        </notes>      </species>      <species id="M_strch2_e" name="starch, structure 2 (1,6-{2[1,4-Glc], [1,4-Glc]})" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H32O16</p>          </body>        </notes>      </species>      <species id="M_strdnc_c" name="stearidonic acid C18:4, n-3" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H27O2</p>          </body>        </notes>      </species>      <species id="M_strdnc_e" name="stearidonic acid C18:4, n-3" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H27O2</p>          </body>        </notes>      </species>      <species id="M_strdnccoa_c" name="stearidonyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H58N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_strdnccoa_m" name="stearidonyl coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H58N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_strdnccoa_x" name="stearidonyl coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H58N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_strdnccrn_c" name="stearidonyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H41NO4</p>          </body>        </notes>      </species>      <species id="M_strdnccrn_m" name="stearidonyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H41NO4</p>          </body>        </notes>      </species>      <species id="M_succ_m" name="Succinate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H4O4</p>          </body>        </notes>      </species>      <species id="M_succoa_m" name="Succinyl-CoA" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H35N7O19P3S</p>          </body>        </notes>      </species>      <species id="M_sucsal_m" name="Succinic semialdehyde" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H5O3</p>          </body>        </notes>      </species>      <species id="M_tag1p_DASH_DASH_DASH_D_c" name="D-Tagatose 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H11O9P</p>          </body>        </notes>      </species>      <species id="M_tag_DASH_hs_c" name="triacylglycerol (homo sapiens)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5FULLRCO2FULLR2CO2FULLR3CO2</p>          </body>        </notes>      </species>      <species id="M_tag_DASH_hs_e" name="triacylglycerol (homo sapiens)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C3H5FULLRCO2FULLR2CO2FULLR3CO2</p>          </body>        </notes>      </species>      <species id="M_tagat_DASH_DASH_DASH_D_c" name="D-Tagatose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_tagat_DASH_DASH_DASH_D_e" name="D-Tagatose" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H12O6</p>          </body>        </notes>      </species>      <species id="M_taur_c" name="Taurine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H7NO3S</p>          </body>        </notes>      </species>      <species id="M_taur_x" name="Taurine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C2H7NO3S</p>          </body>        </notes>      </species>      <species id="M_taxol_c" name="paclitaxel" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C47H31NO14</p>          </body>        </notes>      </species>      <species id="M_taxol_e" name="paclitaxel" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C47H31NO14</p>          </body>        </notes>      </species>      <species id="M_tchola_c" name="taurocholic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H45NO7S</p>          </body>        </notes>      </species>      <species id="M_tchola_e" name="taurocholic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H45NO7S</p>          </body>        </notes>      </species>      <species id="M_tchola_x" name="taurocholic acid" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H45NO7S</p>          </body>        </notes>      </species>      <species id="M_tcynt_c" name="Thiocyanate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CNS</p>          </body>        </notes>      </species>      <species id="M_tcynt_e" name="Thiocyanate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CNS</p>          </body>        </notes>      </species>      <species id="M_tcynt_m" name="Thiocyanate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CNS</p>          </body>        </notes>      </species>      <species id="M_tdchola_c" name="taurochenodeoxycholate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H45NO6S</p>          </body>        </notes>      </species>      <species id="M_tdchola_e" name="taurochenodeoxycholate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H45NO6S</p>          </body>        </notes>      </species>      <species id="M_tdchola_x" name="taurochenodeoxycholate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C26H45NO6S</p>          </body>        </notes>      </species>      <species id="M_tdcoa_c" name="Tetradecanoyl-CoA (n-C14:0CoA)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C35H58N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tdcoa_m" name="Tetradecanoyl-CoA (n-C14:0CoA)" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C35H58N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tethex3_c" name="tetracosahexaenoic acid, n-3" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H35O2</p>          </body>        </notes>      </species>      <species id="M_tethex3_e" name="tetracosahexaenoic acid, n-3" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H35O2</p>          </body>        </notes>      </species>      <species id="M_tethex3coa_c" name="tetracosahexaenoyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H66N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tethex3coa_x" name="tetracosahexaenoyl coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H66N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tetpent3_c" name="tetracosapentaenoic acid, n-3" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H37O2</p>          </body>        </notes>      </species>      <species id="M_tetpent3_e" name="tetracosapentaenoic acid, n-3" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H37O2</p>          </body>        </notes>      </species>      <species id="M_tetpent3coa_c" name="tetracosapentaenoyl coenzyme A, n-3" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H68N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tetpent3coa_x" name="tetracosapentaenoyl coenzyme A, n-3" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H68N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tetpent6_c" name="tetracosapentaenoic acid, n-6" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H37O2</p>          </body>        </notes>      </species>      <species id="M_tetpent6_e" name="tetracosapentaenoic acid, n-6" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H37O2</p>          </body>        </notes>      </species>      <species id="M_tetpent6coa_c" name="tetracosapentaenoyl coenzyme A, n-6" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H68N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tetpent6coa_x" name="tetracosapentaenoyl coenzyme A, n-6" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H68N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tettet6_c" name="tetracosatetraenoic acid n-6" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H39O2</p>          </body>        </notes>      </species>      <species id="M_tettet6_e" name="tetracosatetraenoic acid n-6" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C24H39O2</p>          </body>        </notes>      </species>      <species id="M_tettet6coa_c" name="tetracosatetraenoyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H70N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tettet6coa_x" name="tetracosatetraenoyl coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C45H70N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_thbpt4acam_c" name="Tetrahydrobiopterin-4a-carbinolamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H15N5O4</p>          </body>        </notes>      </species>      <species id="M_thbpt_c" name="Tetrahydrobiopterin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H15N5O3</p>          </body>        </notes>      </species>      <species id="M_thcholoylcoa_x" name="3alpha,7alpha,24-Trihydroxy-5beta-cholestanoyl-CoA" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C48H76N7O20P3S</p>          </body>        </notes>      </species>      <species id="M_thcholst_m" name="3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O4</p>          </body>        </notes>      </species>      <species id="M_thcholstoic_m" name="3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45O5</p>          </body>        </notes>      </species>      <species id="M_thcholstoic_x" name="3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45O5</p>          </body>        </notes>      </species>      <species id="M_thf_c" name="5,6,7,8-Tetrahydrofolate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H21N7O6</p>          </body>        </notes>      </species>      <species id="M_thf_e" name="5,6,7,8-Tetrahydrofolate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H21N7O6</p>          </body>        </notes>      </species>      <species id="M_thf_l" name="5,6,7,8-Tetrahydrofolate" compartment="l" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H21N7O6</p>          </body>        </notes>      </species>      <species id="M_thf_m" name="5,6,7,8-Tetrahydrofolate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C19H21N7O6</p>          </body>        </notes>      </species>      <species id="M_thm_c" name="Thiamin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H17N4OS</p>          </body>        </notes>      </species>      <species id="M_thm_e" name="Thiamin" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H17N4OS</p>          </body>        </notes>      </species>      <species id="M_thmmp_c" name="Thiamin monophosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H16N4O4PS</p>          </body>        </notes>      </species>      <species id="M_thmmp_e" name="Thiamin monophosphate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H16N4O4PS</p>          </body>        </notes>      </species>      <species id="M_thmpp_c" name="Thiamine diphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H16N4O7P2S</p>          </body>        </notes>      </species>      <species id="M_thmtp_c" name="Thiamin triphosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H16N4O10P3S</p>          </body>        </notes>      </species>      <species id="M_thmtp_e" name="Thiamin triphosphate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H16N4O10P3S</p>          </body>        </notes>      </species>      <species id="M_thp2c_c" name="2,3,4,5-Tetrahydropyridine-2-carboxylate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H8NO2</p>          </body>        </notes>      </species>      <species id="M_thp2c_x" name="2,3,4,5-Tetrahydropyridine-2-carboxylate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H8NO2</p>          </body>        </notes>      </species>      <species id="M_thr_DASH_DASH_DASH_L_c" name="L-Threonine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO3</p>          </body>        </notes>      </species>      <species id="M_thr_DASH_DASH_DASH_L_e" name="L-Threonine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H9NO3</p>          </body>        </notes>      </species>      <species id="M_thym_c" name="Thymine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H6N2O2</p>          </body>        </notes>      </species>      <species id="M_thymd_c" name="Thymidine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H14N2O5</p>          </body>        </notes>      </species>      <species id="M_thymd_e" name="Thymidine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H14N2O5</p>          </body>        </notes>      </species>      <species id="M_thymd_m" name="Thymidine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H14N2O5</p>          </body>        </notes>      </species>      <species id="M_thyox_DASH_DASH_DASH_L_c" name="L-Thyroxine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H11I4NO4</p>          </body>        </notes>      </species>      <species id="M_thyox_DASH_DASH_DASH_L_e" name="L-Thyroxine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H11I4NO4</p>          </body>        </notes>      </species>      <species id="M_tmndnc_c" name="timnodonic acid C20:5, n-3" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H29O2</p>          </body>        </notes>      </species>      <species id="M_tmndnc_e" name="timnodonic acid C20:5, n-3" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C20H29O2</p>          </body>        </notes>      </species>      <species id="M_tmndnccoa_c" name="timnodonyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tmndnccoa_m" name="timnodonyl coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tmndnccoa_x" name="timnodonyl coenzyme A" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C41H60N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_tmndnccrn_c" name="Timnodonyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H43NO4</p>          </body>        </notes>      </species>      <species id="M_tmndnccrn_m" name="Timnodonyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H43NO4</p>          </body>        </notes>      </species>      <species id="M_tolbutamide_c" name="tolbutamide" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H18N2O3S</p>          </body>        </notes>      </species>      <species id="M_tolbutamide_e" name="tolbutamide" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C12H18N2O3S</p>          </body>        </notes>      </species>      <species id="M_trdox_c" name="Oxidized thioredoxin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: X</p>          </body>        </notes>      </species>      <species id="M_trdrd_c" name="Reduced thioredoxin" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: XH2</p>          </body>        </notes>      </species>      <species id="M_triodthy_c" name="Triiodothyronine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H12I3NO4</p>          </body>        </notes>      </species>      <species id="M_triodthy_e" name="Triiodothyronine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H12I3NO4</p>          </body>        </notes>      </species>      <species id="M_triodthysuf_c" name="Triiodothyronine sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H11I3NO7S</p>          </body>        </notes>      </species>      <species id="M_triodthysuf_e" name="Triiodothyronine sulfate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H11I3NO7S</p>          </body>        </notes>      </species>      <species id="M_trp_DASH_DASH_DASH_L_c" name="L-Tryptophan" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H12N2O2</p>          </body>        </notes>      </species>      <species id="M_trp_DASH_DASH_DASH_L_e" name="L-Tryptophan" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C11H12N2O2</p>          </body>        </notes>      </species>      <species id="M_tsul_c" name="Thiosulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O3S2</p>          </body>        </notes>      </species>      <species id="M_tsul_e" name="Thiosulfate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O3S2</p>          </body>        </notes>      </species>      <species id="M_tsul_m" name="Thiosulfate" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: O3S2</p>          </body>        </notes>      </species>      <species id="M_ttdca_c" name="tetradecanoate (n-C14:0)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H27O2</p>          </body>        </notes>      </species>      <species id="M_ttdca_e" name="tetradecanoate (n-C14:0)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H27O2</p>          </body>        </notes>      </species>      <species id="M_ttdcrn_c" name="tetradecanoyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H41NO4</p>          </body>        </notes>      </species>      <species id="M_ttdcrn_m" name="tetradecanoyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C21H41NO4</p>          </body>        </notes>      </species>      <species id="M_tym_c" name="Tyramine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H12NO</p>          </body>        </notes>      </species>      <species id="M_tymsf_c" name="Tyramine O-sulfate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H11NO4S</p>          </body>        </notes>      </species>      <species id="M_tymsf_e" name="Tyramine O-sulfate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C8H11NO4S</p>          </body>        </notes>      </species>      <species id="M_tyr_DASH_DASH_DASH_L_c" name="L-Tyrosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11NO3</p>          </body>        </notes>      </species>      <species id="M_tyr_DASH_DASH_DASH_L_e" name="L-Tyrosine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11NO3</p>          </body>        </notes>      </species>      <species id="M_uacgam_c" name="UDP-N-acetyl-D-glucosamine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C17H25N3O17P2</p>          </body>        </notes>      </species>      <species id="M_udp_c" name="UDP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O12P2</p>          </body>        </notes>      </species>      <species id="M_udp_e" name="UDP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O12P2</p>          </body>        </notes>      </species>      <species id="M_udp_n" name="UDP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O12P2</p>          </body>        </notes>      </species>      <species id="M_udp_r" name="UDP" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O12P2</p>          </body>        </notes>      </species>      <species id="M_udpg_c" name="UDPglucose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H22N2O17P2</p>          </body>        </notes>      </species>      <species id="M_udpg_r" name="UDPglucose" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H22N2O17P2</p>          </body>        </notes>      </species>      <species id="M_udpgal_c" name="UDPgalactose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H22N2O17P2</p>          </body>        </notes>      </species>      <species id="M_udpglcur_c" name="UDP-D-glucuronate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H19N2O18P2</p>          </body>        </notes>      </species>      <species id="M_udpglcur_r" name="UDP-D-glucuronate" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C15H19N2O18P2</p>          </body>        </notes>      </species>      <species id="M_ump_c" name="UMP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O9P</p>          </body>        </notes>      </species>      <species id="M_ump_e" name="UMP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O9P</p>          </body>        </notes>      </species>      <species id="M_ump_n" name="UMP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O9P</p>          </body>        </notes>      </species>      <species id="M_ump_r" name="UMP" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O9P</p>          </body>        </notes>      </species>      <species id="M_uppg3_c" name="Uroporphyrinogen III" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C40H36N4O16</p>          </body>        </notes>      </species>      <species id="M_ura_c" name="Uracil" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C4H4N2O2</p>          </body>        </notes>      </species>      <species id="M_urate_c" name="Urate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4N4O3</p>          </body>        </notes>      </species>      <species id="M_urate_e" name="Urate" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4N4O3</p>          </body>        </notes>      </species>      <species id="M_urate_x" name="Urate" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4N4O3</p>          </body>        </notes>      </species>      <species id="M_urcan_c" name="Urocanate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C6H5N2O2</p>          </body>        </notes>      </species>      <species id="M_urea_c" name="Urea" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH4N2O</p>          </body>        </notes>      </species>      <species id="M_urea_e" name="Urea" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH4N2O</p>          </body>        </notes>      </species>      <species id="M_urea_m" name="Urea" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: CH4N2O</p>          </body>        </notes>      </species>      <species id="M_uri_c" name="Uridine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N2O6</p>          </body>        </notes>      </species>      <species id="M_uri_e" name="Uridine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H12N2O6</p>          </body>        </notes>      </species>      <species id="M_utp_c" name="UTP" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O15P3</p>          </body>        </notes>      </species>      <species id="M_utp_e" name="UTP" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O15P3</p>          </body>        </notes>      </species>      <species id="M_utp_n" name="UTP" compartment="n" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C9H11N2O15P3</p>          </body>        </notes>      </species>      <species id="M_vacc_c" name="vaccenic acid" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H33O2</p>          </body>        </notes>      </species>      <species id="M_vacc_e" name="vaccenic acid" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C18H33O2</p>          </body>        </notes>      </species>      <species id="M_vacccoa_c" name="vaccenyl coenzyme A" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_vacccoa_m" name="vaccenyl coenzyme A" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C39H64N7O17P3S</p>          </body>        </notes>      </species>      <species id="M_vacccrn_c" name="Vaccenyl carnitine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H47NO4</p>          </body>        </notes>      </species>      <species id="M_vacccrn_m" name="Vaccenyl carnitine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C25H47NO4</p>          </body>        </notes>      </species>      <species id="M_val_DASH_DASH_DASH_L_c" name="L-Valine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H11NO2</p>          </body>        </notes>      </species>      <species id="M_val_DASH_DASH_DASH_L_e" name="L-Valine" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H11NO2</p>          </body>        </notes>      </species>      <species id="M_val_DASH_DASH_DASH_L_m" name="L-Valine" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H11NO2</p>          </body>        </notes>      </species>      <species id="M_vitd3_c" name="Vitamin D3" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O</p>          </body>        </notes>      </species>      <species id="M_vitd3_m" name="Vitamin D3" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O</p>          </body>        </notes>      </species>      <species id="M_whhdca_c" name="omega hydroxy hexadecanoate (n-C16:0)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H31O3</p>          </body>        </notes>      </species>      <species id="M_whhdca_e" name="omega hydroxy hexadecanoate (n-C16:0)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C16H31O3</p>          </body>        </notes>      </species>      <species id="M_whttdca_c" name="omega hydroxy tetradecanoate (n-C14:0)" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H27O3</p>          </body>        </notes>      </species>      <species id="M_whttdca_e" name="omega hydroxy tetradecanoate (n-C14:0)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C14H27O3</p>          </body>        </notes>      </species>      <species id="M_xan_c" name="Xanthine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4N4O2</p>          </body>        </notes>      </species>      <species id="M_xan_x" name="Xanthine" compartment="x" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H4N4O2</p>          </body>        </notes>      </species>      <species id="M_xmp_c" name="Xanthosine 5&apos;-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H11N4O9P</p>          </body>        </notes>      </species>      <species id="M_xol24oh_r" name="24-Hydroxycholesterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O2</p>          </body>        </notes>      </species>      <species id="M_xol25oh_r" name="25-Hydroxycholesterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O2</p>          </body>        </notes>      </species>      <species id="M_xol27oh_m" name="27-Hydroxycholesterol" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O2</p>          </body>        </notes>      </species>      <species id="M_xol27oh_r" name="27-Hydroxycholesterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O2</p>          </body>        </notes>      </species>      <species id="M_xol7a_r" name="7 alpha-Hydroxycholesterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O2</p>          </body>        </notes>      </species>      <species id="M_xol7ah2_c" name="3alpha,7alpha-Dihydroxy-5beta-cholestane" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H48O2</p>          </body>        </notes>      </species>      <species id="M_xol7ah2_m" name="3alpha,7alpha-Dihydroxy-5beta-cholestane" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H48O2</p>          </body>        </notes>      </species>      <species id="M_xol7ah2al_m" name="3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xol7ah3_m" name="3alpha,7alpha,26-Trihydroxy-5beta-cholestane" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H48O3</p>          </body>        </notes>      </species>      <species id="M_xol7ah_c" name="7alpha-Hydroxy-5beta-cholestan-3-one" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O2</p>          </body>        </notes>      </species>      <species id="M_xol7aone_c" name="7alpha-Hydroxycholest-4-en-3-one" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O2</p>          </body>        </notes>      </species>      <species id="M_xol7aone_r" name="7alpha-Hydroxycholest-4-en-3-one" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O2</p>          </body>        </notes>      </species>      <species id="M_xoldiolone_c" name="7alpha,12alpha-Dihydroxycholest-4-en-3-one" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O3</p>          </body>        </notes>      </species>      <species id="M_xoldiolone_r" name="7alpha,12alpha-Dihydroxycholest-4-en-3-one" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O3</p>          </body>        </notes>      </species>      <species id="M_xoldioloneh_c" name="7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xolest2_DASH_hs_e" name="cholesterol ester (from FULLR2)" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45FULLR2CO2</p>          </body>        </notes>      </species>      <species id="M_xolest_DASH_hs_c" name="cholesterol ester" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45XCO2</p>          </body>        </notes>      </species>      <species id="M_xolest_DASH_hs_e" name="cholesterol ester" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H45XCO2</p>          </body>        </notes>      </species>      <species id="M_xoltetrol_m" name="3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H48O4</p>          </body>        </notes>      </species>      <species id="M_xoltri24_c" name="7-alpha,24(S)-Dihydroxycholesterol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xoltri24_e" name="7-alpha,24(S)-Dihydroxycholesterol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xoltri24_r" name="7-alpha,24(S)-Dihydroxycholesterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xoltri25_c" name="7-alpha,25-Dihydroxycholesterol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xoltri25_e" name="7-alpha,25-Dihydroxycholesterol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xoltri25_r" name="7-alpha,25-Dihydroxycholesterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xoltri27_c" name="7-alpha,27-Dihydroxycholesterol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xoltri27_e" name="7-alpha,27-Dihydroxycholesterol" compartment="e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xoltri27_r" name="7-alpha,27-Dihydroxycholesterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O3</p>          </body>        </notes>      </species>      <species id="M_xoltriol_c" name="3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H48O3</p>          </body>        </notes>      </species>      <species id="M_xoltriol_m" name="3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane" compartment="m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H48O3</p>          </body>        </notes>      </species>      <species id="M_xtsn_c" name="Xanthosine" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C10H12N4O6</p>          </body>        </notes>      </species>      <species id="M_xu1p_DASH_DASH_DASH_D_c" name="D-Xylulose 1-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9O8P</p>          </body>        </notes>      </species>      <species id="M_xu5p_DASH_DASH_DASH_D_c" name="D-Xylulose 5-phosphate" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H9O8P</p>          </body>        </notes>      </species>      <species id="M_xylt_c" name="Xylitol" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H12O5</p>          </body>        </notes>      </species>      <species id="M_xylu_DASH_DASH_DASH_D_c" name="D-Xylulose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10O5</p>          </body>        </notes>      </species>      <species id="M_xylu_DASH_DASH_DASH_L_c" name="L-Xylulose" compartment="c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C5H10O5</p>          </body>        </notes>      </species>      <species id="M_zym_DASH_int2_r" name="zymosterol intermediate 2" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H42O</p>          </body>        </notes>      </species>      <species id="M_zymst_r" name="zymosterol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H44O</p>          </body>        </notes>      </species>      <species id="M_zymstnl_r" name="Zymostenol" compartment="r" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>FORMULA: C27H46O</p>          </body>        </notes>      </species>    </listOfSpecies>    <listOfReactions>      <reaction id="R_10FTHF7GLUtl" name=" 7-glutamyl-10FTHF transport, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf7glu_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf7glu_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_10FTHFtl" name=" 10-Formyltetrahydrofolate lysosomal transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_10FTHFtm" name=" 10-Formyltetrahydrofolate mitochondrial transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_13DAMPPOX" name=" 1,3-Diaminopropane:oxygen oxidoreductase (deaminating)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8639.1) or (26.1) or (314.2) or (314.1)</p>            <p>SUBSYSTEM: beta-Alanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_13dampp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bamppald_c" stoichiometry="1"/>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_1MNCAMti" name="N1-Methylnicotinamide transport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_1mncam_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_1mncam_e" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_1PPDCRp" name="delta1-piperideine-2-carboxylate reductase, perixosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_1pipdn2c_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Lpipecol_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_24NPHte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_24nph_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_24nph_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_25HVITD3t" name=" 25-hydroxyvitamin D3 transport from cytoplasm" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_25hvitd3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_25hvitd3_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_25HVITD3tm" name=" 25-hydroxyvitamin D3 transport from mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_25hvitd3_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_25hvitd3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_2AMACSULT" name=" 2-Aminoacrylate sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2amac_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_paps_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Lcyst_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_2AMADPTm" name="L-2-aminoadipate shuttle (cytosol/mitochondria)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (89874.1)</p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_L2aadp_c" stoichiometry="1"/>          <speciesReference species="M_akg_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_L2aadp_m" stoichiometry="1"/>          <speciesReference species="M_akg_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_2DR1PP" name=" 2-deoxy-D-ribose 1-phosphate phosphorylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2dr1p_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_drib_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_2HBO" name=" 2-Hydroxybutyrate:NAD+ oxidoreductase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (92483.1) or (3948.2) or (55293.1) or (3945.1 and 3939.1) or (3939.1) or (160287.1) or (3945.1) or (3948.1)</p>            <p>SUBSYSTEM: Propanoate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2hb_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2obut_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_2HBt2" name=" 2-hydroxybutyrate cotransport with proton" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9123.1) or (9194.1) or (6566.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2hb_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2hb_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_2HCO3_NAt" name="bicarbonate transport (Na/HCO3 1:2 cotransport)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (57835.3) or (8671.1) or (57835.2) or (57835.1) or (57835.4)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hco3_e" stoichiometry="2"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hco3_c" stoichiometry="2"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_2MCITt" name=" 2-methylcitrate transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2mcit_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2mcit_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_2OXOADOXm" name=" 2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating) (mitochondria)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4967.1) and (1738.1 and 8050.1) and (1743.1) or (4967.2) and (1738.1 and 8050.1) and (1743.1)</p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2oxoadp_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_glutcoa_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_2OXOADPTm" name=" 2-oxoadipate shuttle (cytosol/mitochondria)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (89874.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2oxoadp_c" stoichiometry="1"/>          <speciesReference species="M_akg_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2oxoadp_m" stoichiometry="1"/>          <speciesReference species="M_akg_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_34DHOXPEGOX" name=" 3,4-Dihydroxyphenylethyleneglycol:NAD+ oxidoreductase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (130.1) or (127.1) or (125.1 and 124.1) or (131.1) or (126.1 and 124.1) or (128.1) or (137872.1) or (125.1 and 126.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_34dhmald_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_34dhoxpeg_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_34DHOXPEGt" name=" 3,4-Dihydroxyphenylethyleneglycol transport (diffusion)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_34dhoxpeg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_34dhoxpeg_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_34DHPHEt" name=" 3,4-Dihydroxy-L-phenylalanine transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (117247.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_34dhphe_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_34dhphe_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_34HPPOR" name=" 4-Hydroxyphenylpyruvate:oxygen oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3242.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_34hpp_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_hgentis_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3AIBTm" name="L-3-aminoisobutyrate transaminase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (18.1) or (18.2)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2mop_m" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3aib_m" stoichiometry="1"/>          <speciesReference species="M_akg_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3AIBt" name=" 3-amino-isobutyrate transport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3aib_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3aib_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3AIBtm" name=" 3-amino-isobutyrate transport, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3aib_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3aib_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3DSPHR" name=" 3-Dehydrosphinganine reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2531.1)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3dsphgn_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_sphgn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3HAO" name=" 3-hydroxyanthranilate 3,4-dioxygenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23498.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3hanthrn_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cmusa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3HBCOAHLm" name=" 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3hibutcoa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3hmp_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3HCO3_NAt" name="bicarbonate transport (Na/HCO3 1:3 cotransport)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (57835.3) or (8671.1) or (57835.2) or (57835.1) or (57835.4)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hco3_e" stoichiometry="3"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hco3_c" stoichiometry="3"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3HLYTCL" name=" 3-Hydroxy-L-tyrosine carboxy-lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1644.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_34dhphe_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_dopa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3MLDAt" name=" 3MLDA extracellular transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3mlda_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3mlda_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3SALAASPm" name="cysteinesulfinate-aspartate mitochondrial shuttle" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10165.1) or (8604.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3sala_m" stoichiometry="1"/>          <speciesReference species="M_asp_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3sala_c" stoichiometry="1"/>          <speciesReference species="M_asp_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3SALACBOXL" name=" 3-Sulfino-L-alanine carboxy-lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51380.1) or (2571.1) or (2572.1) or (2571.2)</p>            <p>SUBSYSTEM: Taurine and hypotaurine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3sala_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_hyptaur_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3SALATAi" name=" 3-sulfino-alanine transaminase (irreversible)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2805.1)</p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3sala_c" stoichiometry="1"/>          <speciesReference species="M_akg_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3snpyr_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3SALATAim" name=" 3-sulfino-alanine transaminase (irreversible), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2806.1)</p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3sala_m" stoichiometry="1"/>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3snpyr_m" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3SPYRSP" name=" 3-sulfinopyruvate hydrolase (spotaneous reaction)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3snpyr_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>          <speciesReference species="M_so3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_3SPYRSPm" name=" 3-sulfinopyruvate hydrolase (spotaneous reaction), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3snpyr_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_pyr_m" stoichiometry="1"/>          <speciesReference species="M_so3_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_41R1H2MAE12BOOX" name=" 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4128.1) or (4129.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adrnl_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_34dhmald_c" stoichiometry="1"/>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_mma_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_41R2A1H12BOOX" name=" 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4128.1) or (4129.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nrpphr_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_34dhmald_c" stoichiometry="1"/>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_4ABUTtm" name=" 4-aminobutanoate mitochondrial transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4abut_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4abut_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_4HDEBRISOQUINEte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4hdebrisoquine_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4hdebrisoquine_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_4HGLSDm" name="L-4-hydroxyglutamate semialdehyde dehydrogenase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8659.1) or (8659.2)</p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4hglusa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_e4hglu_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_4HOXPACDOX_LPAREN_NADP_RPAREN_" name=" 4-Hydroxyphenylacetaldehyde:NADP+ oxidoreductase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (222.1) or (220.1) or (221.1) or (218.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4hoxpacd_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4hphac_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_4MTOLBUTAMIDEte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4mtolbutamide_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4mtolbutamide_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_4NPHSFte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4nphsf_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4nphsf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_4NPHSULT" name=" 4-Nitrophenol Sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6799.1) or (6817.3) or (6799.2) or (6818.2) or (6817.2) or (6818.1) or (6817.1) or (6817.4) or (6818.3) or (6817.5)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4nph_c" stoichiometry="1"/>          <speciesReference species="M_paps_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4nphsf_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_4NPHte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4nph_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4nph_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_4PYRDX" name=" 4-Pyridoxal secretion" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4pyrdx_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4pyrdx_e" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5ADTSTSTERONEGLCte" name="glucuronidated compound transport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4363.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5adtststeroneglc_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5adtststeroneglc_e" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5ADTSTSTERONEGLCtr" name="glucuronidated compound transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5adtststeroneglc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5adtststeroneglc_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5ADTSTSTERONESULT" name=" 5alpha-Dihydrotestosterone sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6822.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5adtststerone_c" stoichiometry="1"/>          <speciesReference species="M_paps_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5adtststerones_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5ADTSTSTERONESte" name="sulfonated testosterone transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5adtststerones_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5adtststerones_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5ADTSTSTERONEte" name=" 5 alpha dihydrotesterone transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5adtststerone_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5adtststerone_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5ADTSTSTERONEtr" name=" 5 alpha dihydrotesterone intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5adtststerone_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5adtststerone_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5AOPtm" name=" 5-Aminolevulinate mitochondrial transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Heme Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5aop_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5aop_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5FTHFt2" name=" 5-formyltetrahydrofolate transport via anion exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6573.1) or (6573.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5fthf_e" stoichiometry="1"/>          <speciesReference species="M_oh1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5fthf_c" stoichiometry="1"/>          <speciesReference species="M_oh1_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5HLTDL" name=" 5-Hydroxy-L-tryptophan decarboxy-lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1644.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5htrp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_srtn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5HOMEPRAZOLEte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5homeprazole_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5homeprazole_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5MTHFt" name=" 5-Methyltetrahydrofolate transport via receptor binding and protolysis" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2348.5) or (2348.3) or (2348.1) or (2348.6) or (2352.1) or (2348.4) or (2351.1) or (2348.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5mthf_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5mthf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_5MTHFt2" name=" 5-methyltetrahydrofolate transport via anion exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6573.1) or (6573.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5mthf_e" stoichiometry="1"/>          <speciesReference species="M_oh1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5mthf_c" stoichiometry="1"/>          <speciesReference species="M_oh1_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_7DHCHSTEROLtr" name="cholesterol precursor intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7dhchsterol_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_7dhchsterol_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_7DHFtl" name=" 7-glutamyl-DHF transport, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7dhf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_7dhf_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_7THFtl" name=" 7-glutamyl-THF transport, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7thf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_7thf_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AACTOOR" name="Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8639.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_aact_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_mthgxl_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AACTtm" name="Aminoacetone transport (mitochondrial)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_aact_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_aact_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AAPSAS" name="AAPSAS" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_thp2c_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_L2aadp6sa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AASAD3" name="L-aminoadipate-semialdehyde dehydrogenase (NADH)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_L2aadp6sa_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_L2aadp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AASAD3m" name="L-aminoadipate-semialdehyde dehydrogenase (NADH), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_L2aadp6sa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_L2aadp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AATAi" name=" 2-aminoadipate transaminase, irreversible" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51166.1) or (51166.2)</p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_L2aadp_c" stoichiometry="1"/>          <speciesReference species="M_akg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2oxoadp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ABTArm" name=" 4-aminobutyrate transaminase, reversible (mitochondrial)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (18.1) or (18.2)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4abut_m" stoichiometry="1"/>          <speciesReference species="M_akg_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_sucsal_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ABTD" name="L-arabinitol 4-dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Pentose and Glucuronate Interconversions</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_abt_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_xylu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ABUTD" name="Aminobutyraldehyde dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (223.1)</p>            <p>SUBSYSTEM: beta-Alanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4abutn_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4abut_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ABUTt2r" name=" 4-aminobutyrate reversible transport in via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (206358.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4abut_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4abut_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ABUTt4_LPAREN_2_RPAREN_r" name=" 4-aminobutyrate reversible transport in via sodium symport (1:2)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6529.1) or (6538.1) or (6540.1) or (6539.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4abut_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4abut_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACACT1" name="acetyl-CoA C-acetyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (39.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_aacoa_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACACT10m" name="acetyl-CoA C-acetyltransferase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (38.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2maacoa_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_ppcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACACT1r" name="acetyl-CoA C-acetyltransferase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (39.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_aacoa_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACACT1rm" name="acetyl-CoA C-acetyltransferase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3030.1) and (3032.1) or (38.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_m" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_aacoa_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACACt2" name="acetoacetate transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6566.1) or (9194.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acac_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acac_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACACt2m" name="Acetoacetate mitochondrial transport via H+ symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6566.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acac_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acac_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACACtx" name="acetoacetate intracellular transport unknown mechanism" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acac_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acac_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACALDtm" name="acetaldehyde mitochondrial diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acald_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acald_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACALDtx" name="acetaldehyde peroxisomal diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acald_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acald_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACCOAC" name="acetyl-CoA carboxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (31.2 and 32.1) or (31.1) or (32.1 and 31.3) or (32.1 and 31.5) or (31.4) or (31.4 and 32.1) or (31.2) or (31.3) or (31.1 and 32.1) or (31.5)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_malcoa_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACCOACm" name="Acetyl-Coa carboxylase, beta isoform" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (32.1)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_hco3_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_malcoa_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACCOAL" name="acetate-CoA ligase (ADP-forming)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55902.1) or (55902.2)</p>            <p>SUBSYSTEM: Propanoate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_ppa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_ppcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACETONEt2" name="acetone transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6566.1) or (9123.1) or (9194.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acetone_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acetone_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACETONEt2m" name="acetone mitochondrial transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6566.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acetone_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acetone_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACGAM2E" name="N-acetylglucosamine 2-epimerase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5973.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acgam_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acmana_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACGAM6PSi" name="N-acetylglucosamine-6-phosphate synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (64841.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_c" stoichiometry="1"/>          <speciesReference species="M_gam6p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam6p_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACGAMK" name="N-acetylglucosamine kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55577.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acgam_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam6p_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACGAMPM" name="phosphoacetylglucosamine mutase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5238.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acgam6p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam1p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACGAMtly" name="N-acetyl-glucosamine lysosomal efflux" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acgam_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACITL" name="ATP-Citrate lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (47.1) or (47.2)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_cit_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_oaa_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACNAM9PL" name="N-Acetylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54187.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acmanap_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pep_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acnamp_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACNAM9PL2" name="N-Acetylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54187.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_man6p_c" stoichiometry="1"/>          <speciesReference species="M_pep_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_kdnp_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACNAMPH" name="N-Acetylneuraminate 9-phosphate phosphohydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acnamp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acnam_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACNAMlt" name="N-acetylneuraminate transport into lysososme" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (26503.1)</p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acnam_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acnam_l" stoichiometry="1"/>          <speciesReference species="M_h_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACNMLr" name="N-Acetylneuraminate lyase (reversible)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acnam_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acmana_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACOAD10m" name="acyl-CoA dehydrogenase (2-methylbutanoyl-CoA), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (36.1) or (34.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2mbcoa_m" stoichiometry="1"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2mb2coa_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACOAD1fm" name="acyl-CoA dehydrogenase (butanoyl-CoA), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (80724.1) or (36.1) or (35.1) or (34.1) or (84129.1) or (27034.1) or (28976.1)</p>            <p>SUBSYSTEM: Butanoate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_btcoa_m" stoichiometry="1"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_b2coa_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACOAD8m" name="acyl-CoA dehydrogenase (isovaleryl-CoA), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3712.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_ivcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3mb2coa_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACOAD9m" name="acyl-CoA dehydrogenase (isobutyryl-CoA), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (27034.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_ibcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2mp2coa_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACOAHi" name="acetyl-CoA hydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (134526.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ac_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACOAO7p" name="acyl-CoA oxidase (hexadecanoyl-CoA), peroxisomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51.1) or (51.2)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2_x" stoichiometry="1"/>          <speciesReference species="M_pmtcoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_hdd2coa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACONT" name="aconitase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3658.1) or (48.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cit_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_icit_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACONTm" name="Aconitate hydratase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (50.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cit_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_icit_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACOX22x" name="acyl-Coenzyme A oxidase 2, branched chain" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8309.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhcholoylcoa_x" stoichiometry="1"/>          <speciesReference species="M_fadh2_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="0.5"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fad_x" stoichiometry="1"/>          <speciesReference species="M_thcholoylcoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACOX2x" name="acyl-Coenzyme A oxidase 2, branched chain" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8309.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cholcoas_x" stoichiometry="1"/>          <speciesReference species="M_fadh2_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cholcoads_x" stoichiometry="1"/>          <speciesReference species="M_fad_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACP1_FMN" name="acid phosphatase (FMN)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (52.1) or (52.3) or (52.2)</p>            <p>SUBSYSTEM: Riboflavin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fmn_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_ribflv_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACRNtm" name="O-acetylcarnintine transport into mitochondria via diffusion" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACS" name="acetyl-CoA synthetase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (65985.1) or (55902.2) or (55902.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ac_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_c" stoichiometry="1"/>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACS2" name="acetyl-CoA synthase (propionate)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55902.1) or (65985.1) or (55902.2)</p>            <p>SUBSYSTEM: Propanoate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_ppa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppcoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACSm" name="acetyl-CoA synthetase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (84532.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ac_m" stoichiometry="1"/>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_amp_m" stoichiometry="1"/>          <speciesReference species="M_ppi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACTLMO" name="acetol monooxygenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1571.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acetol_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_mthgxl_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACTNMO" name="acetone monooxygenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1571.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acetone_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acetol_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACYP" name="acylphosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (112611.1) or (98.1) or (97.2) or (97.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_13dpg_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3pg_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ACt2r" name="acetate reversible transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ac_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ac_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADCim" name="Acetoacetate decarboxylation (irreversible), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Propanoate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acac_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acetone_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADK1" name="adenylate kinase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (122481.1) or (203.1) or (26289.1) or (26289.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADK1m" name="adenylate kinase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (205.3) or (205.1) or (204.1) or (204.3) or (204.2) or (205.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amp_m" stoichiometry="1"/>          <speciesReference species="M_atp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADK3m" name="adentylate kinase (GTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (50808.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amp_m" stoichiometry="1"/>          <speciesReference species="M_gtp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_gdp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADMDC" name="adenosylmethionine decarboxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (262.1)</p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amet_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ametam_c" stoichiometry="1"/>          <speciesReference species="M_co2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADNCYC" name="adenylate cyclase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (112.1) or (55811.1) or (109.1) or (112.2) or (114.1) or (108.1) or (113.1) or (107.1) or (196883.1) or (115.1) or (111.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_camp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADNK1" name="adenosine kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (132.1) or (132.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adn_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADNK1m" name="adenosine kinase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adn_m" stoichiometry="1"/>          <speciesReference species="M_atp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_amp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADNt" name="adenosine facilated transport in cytosol" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3177.1) or (2030.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adn_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADNt4" name="adenosine transport (Na/Adn cotransport)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9154.2) or (9154.1) or (64078.1) or (9153.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adn_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adn_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADNtm" name="adenosine facilated transport in mitochondria" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2030.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADPRDP" name="ADPribose diphosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11164.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adprib_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_r5p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADPT" name="adenine phosphoribosyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (353.1)</p>            <p>SUBSYSTEM: Salvage Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ade_c" stoichiometry="1"/>          <speciesReference species="M_prpp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADPtx" name="ADP transporter, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADRNCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adrncoa_c" stoichiometry="1"/>          <speciesReference species="M_crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adrncrn_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADRNCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adrncrn_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adrncoa_m" stoichiometry="1"/>          <speciesReference species="M_crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADRNCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1) or (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adrncrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adrncrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADSK" name="adenylyl-sulfate kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9060.1) or (9061.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_aps_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_paps_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADSL1" name="adenylosuccinate lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (158.1) or (158.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcamp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_fum_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADSL2" name="adenylosuccinate lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (158.1) or (158.2)</p>            <p>SUBSYSTEM: IMP Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_25aics_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_aicar_c" stoichiometry="1"/>          <speciesReference species="M_fum_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ADSS" name="adenylosuccinate synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (159.1) or (122622.1) or (122622.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_asp_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_gtp_c" stoichiometry="1"/>          <speciesReference species="M_imp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcamp_c" stoichiometry="1"/>          <speciesReference species="M_gdp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AFLATOXINte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_aflatoxin_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_aflatoxin_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AGPAT1" name=" 1-acylglycerol-3-phosphate O-acyltransferase 1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10555.1) or (137964.1) or (56895.1) or (56894.2) or (56894.1) or (55326.1) or (10554.1)</p>            <p>SUBSYSTEM: Triacylglycerol Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal2coa_c" stoichiometry="1"/>          <speciesReference species="M_alpa_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_pa_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AGTix" name="alanine-glyoxylate transaminase (irreversible), (peroxisomal)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (189.1)</p>            <p>SUBSYSTEM: Alanine and Aspartate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_x" stoichiometry="1"/>          <speciesReference species="M_glx_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gly_x" stoichiometry="1"/>          <speciesReference species="M_pyr_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AHC" name="adenosylhomocysteinase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (191.1) or (10768.2) or (10768.1)</p>            <p>SUBSYSTEM: Methionine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ahcys_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adn_c" stoichiometry="1"/>          <speciesReference species="M_hcys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AHCYStr" name="S-Adenosyl-L-homocysteine intracellular diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ahcys_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ahcys_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AHEXASE2ly" name="beta-N-acetylhexosaminidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3074.1) or (3073.1) or (3073.1 and 3074.1)</p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="3"/>          <speciesReference species="M_n2m2nmn_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam_l" stoichiometry="3"/>          <speciesReference species="M_m2mn_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AHEXASEly" name="beta-N-acetylhexosaminidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3073.1) or (3074.1) or (3073.1 and 3074.1)</p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="2"/>          <speciesReference species="M_n2m2mn_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam_l" stoichiometry="2"/>          <speciesReference species="M_m2mn_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AICART" name="phosphoribosylaminoimidazolecarboxamide formyltransferase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (471.1)</p>            <p>SUBSYSTEM: IMP Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf_c" stoichiometry="1"/>          <speciesReference species="M_aicar_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fprica_c" stoichiometry="1"/>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AIRCr" name="phosphoribosylaminoimidazole carboxylase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10606.1)</p>            <p>SUBSYSTEM: IMP Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_air_c" stoichiometry="1"/>          <speciesReference species="M_co2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5aizc_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AKGMALtm" name="alpha-ketoglutarate/malate transporter" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8402.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_mal_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_akg_c" stoichiometry="1"/>          <speciesReference species="M_mal_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AKR1C41" name="aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1109.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_xol7ah_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_xol7ah2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AKR1C42" name="aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1109.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_xoldioloneh_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_xoltriol_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AKR1D" name="aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6718.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_xol7aone_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_xol7ah_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AKR1D2" name="aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6718.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_xoldiolone_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_xoldioloneh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALACYSNaEx" name="L-alanine/L-cysteine Na-dependent exchange (Ala-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_cys_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALAR" name="alanine racemase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11212.1)</p>            <p>SUBSYSTEM: Alanine and Aspartate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALASERNaEx" name="L-alanine/L-serine Na-dependent exchange (Ala-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALASm" name=" 5-aminolevulinate synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (212.1) or (23464.1) or (211.2) or (211.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gly_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_succoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5aop_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALATA_L" name="L-alanine transaminase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2875.1) or (84706.1)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_c" stoichiometry="1"/>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALATHRNaEx" name="L-alanine/L-threonine Na-dependent exchange (Ala-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALAt4" name="Alanine-Sodium symporter" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54407.1) or (6542.1) or (11254.1) or (6541.1) or (81539.1) or (55089.1) or (84889.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALAtN1" name="Alanine transport (Na, H coupled)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (92745.1) or (10991.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALCD1" name="alcohol dehydrogenase (methanol)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (131.1) or (130.1) or (126.1 and 124.1) or (128.1) or (125.1) or (137872.1) or (125.1 and 124.1) or (284273.1) or (124.1) or (125.1 and 126.1) or (284273.2) or (127.1) or (126.1)</p>            <p>SUBSYSTEM: Miscellaneous</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_meoh_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fald_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALCD21_D" name="alcohol dehydrogenase (D-1,2-propanediol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (125.1 and 126.1) or (131.1) or (284273.1) or (126.1) or (128.1) or (125.1 and 124.1) or (124.1) or (127.1) or (137872.1) or (284273.2) or (126.1 and 124.1) or (130.1) or (125.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_12ppd_DASH_DASH_DASH_R_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lald_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALCD21_L" name="alcohol dehydrogenase (L-1,2-propanediol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (127.1) or (284273.1) or (131.1) or (126.1) or (125.1) or (125.1 and 124.1) or (137872.1) or (125.1 and 126.1) or (124.1) or (130.1) or (126.1 and 124.1) or (284273.2) or (128.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_12ppd_DASH_DASH_DASH_S_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lald_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALCD22_D" name="alcohol dehydrogenase (D-lactaldehyde)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (126.1) or (137872.1) or (126.1 and 124.1) or (127.1) or (130.1) or (284273.1) or (125.1 and 124.1) or (128.1) or (124.1) or (125.1) or (284273.2) or (131.1) or (125.1 and 126.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lald_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mthgxl_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALCD22_L" name="alcohol dehydrogenase (L-lactaldehyde)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (126.1) or (137872.1) or (126.1 and 124.1) or (127.1) or (130.1) or (284273.1) or (125.1 and 124.1) or (128.1) or (124.1) or (125.1) or (284273.2) or (131.1) or (125.1 and 126.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lald_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mthgxl_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALCD2if" name="alcohol dehydrogenase, forward rxn (ethanol -&gt; acetaldehyde)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (126.1) or (127.1) or (284273.2) or (125.1 and 124.1) or (126.1 and 124.1) or (128.1) or (284273.1) or (131.1) or (126.1) or (137872.1) or (124.1) or (130.1) or (125.1 and 126.1) or (125.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_etoh_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acald_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALCD2yf" name="alcohol dehydrogenase (ethanol, NADP), forward reaction" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10327.1) or (10327.2)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_etoh_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acald_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALDD19x_LPAREN_P_RPAREN_" name="aldehyde dehydrogenase (phenylacetaldehyde, NADP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (222.1) or (218.1) or (221.1) or (220.1)</p>            <p>SUBSYSTEM: Phenylalanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_pacald_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_pac_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALDD2x" name="aldehyde dehydrogenase (acetaldehyde, NAD)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (218.1) or (501.1) or (8854.2) or (224.1) or (222.1) or (8854.1) or (221.1) or (216.1) or (8854.3) or (223.1) or (220.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acald_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ac_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALDD2xm" name="aldehyde dehydrogenase (acetylaldehyde, NAD), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (219.1) or (217.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acald_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ac_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALDD2y" name="aldehyde dehydrogenase (acetaldehyde, NADP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (223.1) or (221.1) or (218.1) or (8854.1) or (8854.3) or (222.1) or (8854.2) or (224.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acald_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ac_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALOX5" name="Arachidonate 5-lipoxygenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (240.1)</p>            <p>SUBSYSTEM: Eicosanoid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachd_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5HPET_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALOX52" name="Arachidonate 5-lipoxygenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (240.1)</p>            <p>SUBSYSTEM: Eicosanoid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5HPET_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_leuktrA4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALR" name="Aldose reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (231.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mthgxl_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALR2" name="aldose reductase (methylglyoxal)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10327.2) or (8574.1) or (10327.1) or (231.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mthgxl_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acetol_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ALR3" name="aldose reductase (acetol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10327.2) or (8574.1) or (10327.1) or (231.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acetol_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_12ppd_DASH_DASH_DASH_S_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AM6SAD" name="aminomuconate-semialdehyde dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_am6sa_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amuco_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMACR2p" name="alpha-methylacyl-CoA racemase (reductase)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23600.1) or (23600.2)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhcholestancoa_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="0.5"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhcholoylcoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMACRp" name="alpha-methylacyl-CoA racemase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23600.2) or (23600.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cholcoar_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cholcoas_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMANK" name="N-acetyl-D-mannosamine kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10020.1) or (55577.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acmana_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acmanap_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMCOXO" name=" 2-aminomuconate reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amuco_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2oxoadp_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMETr" name="S-Adenosyl-L-methionine intracellular diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amet_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amet_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMETt2m" name="S-Adenosyl-L-methionine reversible transport, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (115286.3) or (115286.2) or (115286.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ahcys_m" stoichiometry="1"/>          <speciesReference species="M_amet_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ahcys_c" stoichiometry="1"/>          <speciesReference species="M_amet_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMPDA" name="Adenosine monophosphate deaminase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (271.2) or (270.1) or (271.1) or (272.1) or (271.3)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_imp_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMPTASECG" name="alanyl aminopeptidase (cys-gly)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (290.1)</p>            <p>SUBSYSTEM: Glutathione Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cgly_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_gly_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMPTASECGe" name="alanyl aminopeptidase (cys-gly) (e)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (290.1)</p>            <p>SUBSYSTEM: Glutathione Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cgly_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cys_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_gly_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMPtp" name="AMP transporter, peroxisome" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMY1e" name="alpha-amylase, extracellular (strch1 -&gt; strch2)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6520.1) or (280.1) or (278.1) or (276.1) or (277.1) or (6519.1 and 11136.1) or (276.2) or (279.1)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_e" stoichiometry="8"/>          <speciesReference species="M_strch1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glc_DASH_DASH_DASH_D_e" stoichiometry="8"/>          <speciesReference species="M_strch2_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AMY2e" name="alpha-amylase, extracellular (glygn2 -&gt; glygn4)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6520.1) or (280.1) or (278.1) or (276.1) or (277.1) or (6519.1 and 11136.1) or (276.2) or (279.1)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glygn2_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="8"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glc_DASH_DASH_DASH_D_e" stoichiometry="8"/>          <speciesReference species="M_glygn4_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ANTIPYRENEte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_antipyrene_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_antipyrene_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_AOBUTDsm" name="L-2-amino-3-oxobutanoate decarboxylation, mitochondrial  (spontaneous)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2aobut_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_aact_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_APAT2rm" name=" 3-Aminopropanoate:2-oxoglutarate aminotransferase (m)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (18.1) or (18.2)</p>            <p>SUBSYSTEM: beta-Alanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_ala_DASH_DASH_DASH_B_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_msa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_APNNOXte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_apnnox_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_apnnox_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_APOCF" name="Apocarboxylase formation" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_apoC_c" stoichiometry="1"/>          <speciesReference species="M_lys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_apoC_DASH_DASH_DASH_Lys_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_APOCFm" name="Apocarboxylase formation, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_apoC_m" stoichiometry="1"/>          <speciesReference species="M_lys_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_apoC_DASH_DASH_DASH_Lys_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_APOC_LYS_BTNP" name="proteolysis of apoC-Lys-btn" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_apoC_DASH_DASH_DASH_Lys_DASH_btn_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_apoC_c" stoichiometry="1"/>          <speciesReference species="M_biocyt_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_APOC_LYS_BTNPm" name="proteolysis of apoC-Lys-btn, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_apoC_DASH_DASH_DASH_Lys_DASH_btn_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_apoC_m" stoichiometry="1"/>          <speciesReference species="M_biocyt_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_APPNNte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_appnn_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_appnn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARABR" name="arabinose reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10327.2) or (8574.1) or (10327.1) or (231.1)</p>            <p>SUBSYSTEM: Pentose and Glucuronate Interconversions</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arab_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_abt_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARAB_Lt" name="L-arabinoase extracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arab_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arab_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARACHCPT1" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.3) or (1374.1) or (1375.2) or (1375.4) or (1375.1) or (126129.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachcoa_c" stoichiometry="1"/>          <speciesReference species="M_crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arachcrn_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARACHCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachcrn_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arachcoa_m" stoichiometry="1"/>          <speciesReference species="M_crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARACHCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arachcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARACHDCOAtx" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachdcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arachdcoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARACHDt2" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachd_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arachd_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARGN" name="arginase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (383.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arg_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_orn_c" stoichiometry="1"/>          <speciesReference species="M_urea_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARGNm" name="arginase (m)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (384.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arg_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_orn_m" stoichiometry="1"/>          <speciesReference species="M_urea_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARGSL" name="argininosuccinate lyase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (435.1)</p>            <p>SUBSYSTEM: Alanine and Aspartate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_argsuc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arg_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_fum_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARGSS" name="argininosuccinate synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (445.1) or (445.2)</p>            <p>SUBSYSTEM: Alanine and Aspartate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_asp_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_citr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_argsuc_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARGtiDF" name="L-arginine transport via diffusion (extracellular to cytosol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6541.1) or (6542.1) or (55089.1) or (84889.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arg_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arg_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARGtm" name="arginine mitochondrial transport via ornithine carrier" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (83884.1) or (10166.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arg_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arg_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTCOAL1" name="R group coenzyme a ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotalcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTCOAL2" name="R group coenzyme a ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal2_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal2coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTCOAL3" name="R group coenzyme a ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal3_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal3coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTFR13" name="R group artificial flux" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tdcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_R1coa_DASH_hs_c" stoichiometry="0.875"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTFR211" name="R group artificial flux" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_clpndcoa_c" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="3"/>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_nadph_m" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_R2coa_DASH_hs_c" stoichiometry="1.375"/>          <speciesReference species="M_fad_m" stoichiometry="3"/>          <speciesReference species="M_nadp_m" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTPLM1" name="R group to palmitate conversion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotalcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pmtcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTPLM1m" name="R group to palmitate conversion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotalcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pmtcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTPLM2" name="R group to palmitate conversion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal2coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pmtcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTPLM2m" name="R group to palmitate conversion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal2coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pmtcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTPLM3" name="R group to palmitate conversion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal3coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pmtcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ARTPLM3m" name="R group to palmitate conversion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: R Group Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal3coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pmtcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ASAH1" name="N-acylsphingosine amidohydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (427.1) or (427.2)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crm_DASH_hs_l" stoichiometry="1"/>          <speciesReference species="M_h2o_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal_l" stoichiometry="1"/>          <speciesReference species="M_sphings_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ASCBt4" name="L-ascorbate transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9962.2) or (9963.1) or (9962.1) or (9963.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ascb_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ascb_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ASNS1" name="asparagine synthase (glutamine-hydrolysing)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (440.1) or (440.3) or (440.2)</p>            <p>SUBSYSTEM: Alanine and Aspartate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_asp_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_asn_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ASNt4" name="L-asparagine transport in via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (81539.1) or (11254.1) or (54407.1) or (55089.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_asn_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_asn_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ASNtN1" name="Asparagine transport (Na, H coupled)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (92745.1) or (10991.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_asn_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_asn_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ASPCTr" name="aspartate carbamoyltransferase (reversible)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (790.1)</p>            <p>SUBSYSTEM: Pyrimidine Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_asp_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_cbp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cbasp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ASPGLUm" name="aspartate-glutamate mitochondrial shuttle" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8604.1) or (10165.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_asp_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_asp_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ASPTA" name="aspartate transaminase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2805.1)</p>            <p>SUBSYSTEM: Alanine and Aspartate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_c" stoichiometry="1"/>          <speciesReference species="M_asp_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_oaa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ASPTAm" name="aspartate transaminase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2806.1)</p>            <p>SUBSYSTEM: Alanine and Aspartate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_asp_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_oaa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ASPt6" name="L-aspartate transport via Na, H symport and K antiport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6511.1) or (6505.1) or (6507.1) or (6506.1) or (6512.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_asp_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_k_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_asp_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_k_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="3"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ATPH1e" name="ATP diphosphohydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (954.1) or (954.2) or (953.1) or (956.1) or (955.1) or (957.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="2"/>          <speciesReference species="M_pi_e" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ATPH2e" name="ATP diphosphohydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (954.2) or (954.1) or (953.1) or (956.1) or (955.1) or (957.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adp_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ATPS4m" name="ATP synthase (four protons for one ATP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (498.2 and 509.1 and 513.2 and 506.1 and 514.1 or 513.1 and 506.1 and 498.3 and 509.2 and 514.1 or 513.2 and 498.1 and 506.1 and 509.2 and 514.1 or 513.1 and 509.1 and 506.1 and 498.3 and 514.1 or 513.1 and 509.1 and 498.1 and 514.2 and 506.1 or 513.1 and 514.2 and 506.1 and 498.3 and 509.2 or 513.1 and 509.1 and 498.1 and 506.1 and 514.1 or 513.1 and 509.1 and 514.2 and 506.1 and 498.3 or 513.2 and 506.1 and 498.3 and 509.2 and 514.1 or 498.2 and 513.2 and 514.2 and 506.1 and 509.2 or 513.1 and 498.2 and 506.1 and 509.2 and 514.1 or 513.1 and 498.1 and 514.2 and 506.1 and 509.2 or 509.1 and 513.2 and 498.1 and 506.1 and 514.1 or 513.1 and 498.2 and 509.1 and 506.1 and 514.1 or 498.2 and 509.1 and 513.2 and 514.2 and 506.1 or 509.1 and 513.2 and 514.2 and 506.1 and 498.3 or 513.1 and 498.2 and 514.2 and 506.1 and 509.2 or 498.2 and 513.2 and 506.1 and 509.2 and 514.1 or 513.2 and 498.1 and 514.2 and 506.1 and 509.2 or 509.1 and 513.2 and 498.1 and 514.2 and 506.1 or 513.2 and 514.2 and 506.1 and 498.3 and 509.2 or 509.1 and 513.2 and 506.1 and 498.3 and 514.1 or 513.1 and 498.2 and 509.1 and 514.2 and 506.1 or 513.1 and 498.1 and 506.1 and 509.2 and 514.1) and (10632.1 and 4905.1 and 10476.1 and 9551.1 and 515.2 and 522.5 and 518.2 and 521.1 or 4905.1 and 522.1 and 521.1 and 516.2 and 515.1 and 10632.1 and 10476.1 and 9551.2 or 10632.1 and 4905.1 and 516.1 and 10476.2 and 515.2 and 522.5 and 9551.2 and 521.1 or 10632.1 and 518.3 and 4905.1 and 10476.1 and 9551.1 and 522.1 and 521.1 and 515.1 or 4905.1 and 9551.1 and 515.3 and 10476.2 and 521.1 and 516.2 and 10632.1 and 522.5 or 10632.1 and 4905.1 and 516.1 and 522.2 and 9551.3 and 10476.2 and 521.1 and 515.1 or 10632.1 and 517.1 and 4905.1 and 10476.1 and 9551.1 and 515.2 and 522.4 and 521.1 or 518.3 and 4905.1 and 522.2 and 515.3 and 10476.2 and 521.1 and 10632.1 and 9551.2 or 4905.1 and 515.3 and 10476.2 and 521.1 and 10632.1 and 522.5 and 518.2 and 9551.2 or 10632.1 and 4905.1 and 10476.1 and 515.2 and 522.1 and 9551.2 and 518.2 and 521.1 or 4905.1 and 10476.2 and 515.2 and 522.1 and 521.1 and 10632.1 and 9551.3 and 518.2 or 10632.1 and 4905.1 and 10476.1 and 515.3 and 9551.3 and 522.1 and 521.1 and 516.2 or 4905.1 and 9551.1 and 10476.2 and 515.2 and 521.1 and 10632.1 and 517.2 and 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10632.1 and 9551.3 and 522.4 or 4905.1 and 522.2 and 9551.1 and 10476.2 and 515.2 and 521.1 and 516.2 and 10632.1 or 518.3 and 4905.1 and 515.3 and 10476.2 and 521.1 and 10632.1 and 9551.3 and 522.4 or 4905.1 and 515.3 and 10476.2 and 521.1 and 518.1 and 10632.1 and 9551.3 and 522.5 or 10632.1 and 517.1 and 4905.1 and 10476.1 and 9551.1 and 515.2 and 522.3 and 521.1 or 518.3 and 4905.1 and 10476.2 and 521.1 and 515.1 and 10632.1 and 9551.3 and 522.3 or 10632.1 and 517.1 and 4905.1 and 10476.1 and 9551.3 and 522.5 and 521.1 and 515.1 or 10632.1 and 4905.1 and 10476.1 and 515.3 and 9551.3 and 522.5 and 521.1 and 516.2 or 10632.1 and 4905.1 and 516.1 and 10476.2 and 515.2 and 9551.2 and 522.3 and 521.1 or 4905.1 and 9551.1 and 10476.2 and 521.1 and 516.2 and 515.1 and 10632.1 and 522.5 or 10632.1 and 4905.1 and 516.1 and 522.2 and 9551.1 and 10476.2 and 515.2 and 521.1 or 4905.1 and 9551.1 and 10476.2 and 515.2 and 522.1 and 521.1 and 10632.1 and 518.2 or 4905.1 and 10476.2 and 522.1 and 521.1 and 518.1 and 515.1 and 10632.1 and 9551.2 or 10632.1 and 4905.1 and 10476.1 and 515.3 and 517.2 and 522.1 and 9551.2 and 521.1 or 518.3 and 4905.1 and 10476.2 and 521.1 and 515.1 and 10632.1 and 9551.2 and 522.4 or 10632.1 and 517.1 and 4905.1 and 10476.1 and 9551.1 and 522.5 and 521.1 and 515.1 or 10632.1 and 517.1 and 4905.1 and 10476.1 and 515.2 and 9551.2 and 522.3 and 521.1 or 10632.1 and 4905.1 and 10476.1 and 9551.3 and 522.3 and 521.1 and 516.2 and 515.1 or 10632.1 and 4905.1 and 10476.1 and 522.2 and 515.3 and 9551.2 and 521.1 and 518.1 or 10632.1 and 4905.1 and 10476.1 and 516.1 and 9551.1 and 515.3 and 522.4 and 521.1 or 4905.1 and 522.2 and 10476.2 and 515.2 and 521.1 and 516.2 and 10632.1 and 9551.2 or 10632.1 and 4905.1 and 10476.1 and 522.4 and 9551.2 and 518.2 and 521.1 and 515.1 or 10632.1 and 518.3 and 4905.1 and 10476.1 and 9551.2 and 522.3 and 521.1 and 515.1 or 4905.1 and 515.3 and 10476.2 and 521.1 and 10632.1 and 517.2 and 522.5 and 9551.2 or 517.1 and 4905.1 and 522.2 and 10476.2 and 515.2 and 521.1 and 10632.1 and 9551.3 or 10632.1 and 517.1 and 4905.1 and 10476.1 and 9551.1 and 515.3 and 522.3 and 521.1 or 4905.1 and 515.3 and 522.2 and 521.1 and 10632.1 and 10476.1 and 9551.3 and 518.2 or 10632.1 and 4905.1 and 10476.1 and 516.1 and 9551.3 and 522.4 and 521.1 and 515.1 or 10632.1 and 4905.1 and 10476.1 and 516.1 and 9551.1 and 515.2 and 522.1 and 521.1 or 10632.1 and 4905.1 and 10476.1 and 9551.1 and 517.2 and 522.4 and 521.1 and 515.1 or 10632.1 and 518.3 and 4905.1 and 10476.1 and 9551.3 and 515.2 and 522.3 and 521.1 or 10632.1 and 4905.1 and 10476.1 and 522.2 and 9551.1 and 515.3 and 517.2 and 521.1 or 10632.1 and 4905.1 and 10476.1 and 9551.2 and 522.3 and 521.1 and 518.1 and 515.1 or 10632.1 and 4905.1 and 516.1 and 9551.1 and 10476.2 and 522.5 and 521.1 and 515.1 or 4905.1 and 10476.2 and 521.1 and 516.2 and 515.1 and 10632.1 and 522.5 and 9551.2 or 10632.1 and 4905.1 and 10476.1 and 9551.1 and 515.2 and 522.1 and 521.1 and 516.2 or 518.3 and 4905.1 and 9551.1 and 515.3 and 10476.2 and 521.1 and 10632.1 and 522.5 or 10632.1 and 4905.1 and 10476.2 and 9551.3 and 522.1 and 518.1 and 521.1 and 515.1 or 10632.1 and 4905.1 and 10476.1 and 9551.1 and 515.2 and 522.4 and 521.1 and 518.1 or 10632.1 and 517.1 and 4905.1 and 10476.1 and 9551.3 and 522.3 and 521.1 and 515.1 or 10632.1 and 4905.1 and 10476.1 and 9551.3 and 517.2 and 522.5 and 521.1 and 515.1 or 517.1 and 4905.1 and 515.3 and 10476.2 and 522.1 and 521.1 and 10632.1 and 9551.3)</p>            <p>SUBSYSTEM: Oxidative Phosphorylation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="4"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="3"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ATPtm" name="ADP/ATP transporter, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (291.1) or (293.1) or (292.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_atp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ATPtn" name="ATP diffusion in nucleus" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_atp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ATPtx" name="ATP transporter, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_atp_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_A_MANASEly" name="alpha-mannosidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4125.1)</p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="2"/>          <speciesReference species="M_m2mn_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_man_l" stoichiometry="2"/>          <speciesReference species="M_mn_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BAAT1x" name="bile acid Coenzyme A: amino acid N-acyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (570.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cholcoa_x" stoichiometry="1"/>          <speciesReference species="M_gly_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_gchola_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BAAT2x" name="bile acid Coenzyme A: amino acid N-acyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (570.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cholcoa_x" stoichiometry="1"/>          <speciesReference species="M_taur_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_tchola_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BAAT3x" name="bile acid Coenzyme A: amino acid N-acyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (570.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dgcholcoa_x" stoichiometry="1"/>          <speciesReference species="M_gly_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_dgchol_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BAAT4x" name="bile acid Coenzyme A: amino acid N-acyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (570.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcholcoa_x" stoichiometry="1"/>          <speciesReference species="M_gly_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_gdchola_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BAAT5x" name="bile acid Coenzyme A: amino acid N-acyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (570.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcholcoa_x" stoichiometry="1"/>          <speciesReference species="M_taur_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_tdchola_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BACCL" name="biotin-[acetyl-CoA-carboxylase] ligase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3141.1)</p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_btn_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_btamp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BACCLm" name="biotin-[acetyl-CoA-carboxylase] ligase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3141.1)</p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_btn_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_btamp_m" stoichiometry="1"/>          <speciesReference species="M_ppi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BALAtmr" name="Beta-alanine reversible mitochondrial transport (diffusion)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_B_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_B_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BAMPPALDOX" name="beta-Aminopropion aldehyde:NAD+ oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8854.2) or (501.1) or (216.1) or (224.1) or (8854.3) or (223.1) or (8854.1)</p>            <p>SUBSYSTEM: beta-Alanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bamppald_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_B_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BDHm" name="(R)-3-Hydroxybutanoate:NAD+ oxidoreductase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (622.2) or (622.3) or (622.1)</p>            <p>SUBSYSTEM: Butanoate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bhb_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acac_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BETALDHxm" name="betaine-aldehyde dehydrogenase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_betald_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glyb_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BHBt" name="(R)-3-Hydroxybutanoate transport via H+ symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bhb_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bhb_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BHBtm" name="(R)-3-Hydroxybutanoate mitochondrial transport via H+ symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bhb_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bhb_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BHMT" name="betaine-homocysteine S-methyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23743.1) or (635.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glyb_c" stoichiometry="1"/>          <speciesReference species="M_hcys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dmgly_c" stoichiometry="1"/>          <speciesReference species="M_met_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BILDGLCURt" name="bilirubin beta-diglucuronide transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10599.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bildglcur_e" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bildglcur_c" stoichiometry="1"/>          <speciesReference species="M_hco3_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BILDGLCURte" name="bilirubin beta-diglucuronide transport MDR" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4363.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_bildglcur_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_bildglcur_e" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BILDGLCURtr" name="glucuronidated compound transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bildglcur_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bildglcur_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BILGLCURt" name="bilirubin monoglucuronide transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10599.1) or (28234.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bilglcur_e" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bilglcur_c" stoichiometry="1"/>          <speciesReference species="M_hco3_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BILGLCURte" name="bilirubin monoglucuronide transport MDR" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4363.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_bilglcur_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_bilglcur_e" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BILGLCURtr" name="glucuronidated compound transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bilglcur_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bilglcur_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BILIRED" name="Nad(p)h biliverdin reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (645.1) or (644.1)</p>            <p>SUBSYSTEM: Heme Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_biliverd_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bilirub_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BILIRUBt2" name="bilirubin transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10599.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bilirub_e" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bilirub_c" stoichiometry="1"/>          <speciesReference species="M_hco3_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BILIRUBtr" name="lipid, flip-flop intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bilirub_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bilirub_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BIOCYTtn" name="biocytin transport, nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_biocyt_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_biocyt_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BPNT" name=" 3&apos;,5&apos;-bisphosphate nucleotidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10380.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BPNT2" name=" 3&apos;,5&apos;-bisphosphate nucleotidase (paps)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10380.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_paps_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_aps_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BTND1" name="biotinidase (biotin)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (686.1)</p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_biocyt_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_btn_c" stoichiometry="1"/>          <speciesReference species="M_lys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BTND1n" name="biotinidase (biotin), nuclear" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (686.1)</p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_biocyt_n" stoichiometry="1"/>          <speciesReference species="M_h2o_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_btn_n" stoichiometry="1"/>          <speciesReference species="M_lys_DASH_DASH_DASH_L_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BTNDe" name="biotinidase (biotin), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (686.1)</p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_biocyt_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_btn_e" stoichiometry="1"/>          <speciesReference species="M_lys_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BTNDm" name="biotinidase (biotin), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (686.1)</p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_biocyt_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_btn_m" stoichiometry="1"/>          <speciesReference species="M_lys_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BTNPL" name="holocarboxylase synthestase (biotin protein ligase)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3141.1)</p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_apoC_DASH_DASH_DASH_Lys_c" stoichiometry="1"/>          <speciesReference species="M_btamp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_apoC_DASH_DASH_DASH_Lys_DASH_btn_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BTNPLm" name="holocarboxylase synthestase (biotin protein ligase), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3141.1)</p>            <p>SUBSYSTEM: Biotin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_apoC_DASH_DASH_DASH_Lys_m" stoichiometry="1"/>          <speciesReference species="M_btamp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_m" stoichiometry="1"/>          <speciesReference species="M_apoC_DASH_DASH_DASH_Lys_DASH_btn_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BTNt2" name="Biotin reversible transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6566.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_btn_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_btn_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BTNt4i" name="Biotin uptake (antiport)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (80704.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_btn_e" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_btn_c" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BTNtn" name="Biotin transport, nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_btn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_btn_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BUP2" name="beta-ureidopropionase (D-3-amino-isobutanoate forming)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51733.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3uib_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3aib_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BUTt2m" name="Butyrate mitochondrial transport via proton symport, reversible" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6566.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_but_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_but_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_BUTt2r" name="Butyrate transport via proton symport, reversible" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6566.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_but_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_but_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_B_MANNASEly" name="beta-mannosidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4126.1)</p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="1"/>          <speciesReference species="M_mn_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam_l" stoichiometry="1"/>          <speciesReference species="M_man_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C14STRr" name="C-14 sterol reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7108.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_44mctr_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_44mzym_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C160CPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (126129.1) or (1375.3) or (1374.1) or (1375.2) or (1375.1) or (1375.4)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_pmtcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_pmtcrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C160CPT2" name="C160 transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_pmtcrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_pmtcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C160CRNt" name="C160 transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pmtcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pmtcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C161CPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_hdcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_hdcecrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C161CPT12" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (126129.1) or (1375.3) or (1375.1) or (1375.2) or (1374.1) or (1375.4)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_hdd2coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_hdd2crn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C161CPT2" name="C161 transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_hdcecrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_hdcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C161CPT22" name="C161 transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_hdd2crn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_hdd2coa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C161CRN2t" name="C161 transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hdd2crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hdd2crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C161CRNt" name="C161 transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hdcecrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hdcecrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C180CPT1" name="carnitine O-stearoyl transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.4) or (1375.2) or (126129.1) or (1375.1) or (1374.1) or (1375.3)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_stcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_stcrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C180CPT2" name="carnitine O-stearoyl transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_stcrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_stcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C180CRNt" name="C180 transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_stcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_stcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C181CPT1" name="carnitine octadecenoyl transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (126129.1) or (1375.3) or (1374.1) or (1375.2) or (1375.1) or (1375.4)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_odecoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_odecrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C181CPT2" name="carnitine octadecenoyl transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_odecrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_odecoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C181CRNt" name="C181 transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_odecrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_odecrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C204CPT1" name="carnitine C20:4 transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1374.1) or (1375.4) or (1375.1) or (1375.3) or (1375.2) or (126129.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachdcoa_c" stoichiometry="1"/>          <speciesReference species="M_crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arachdcrn_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C204CPT2" name="arachidonic acid transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachdcrn_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arachdcoa_m" stoichiometry="1"/>          <speciesReference species="M_crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C204CRNt" name="arachidonic acid transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachdcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arachdcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C226CPT1" name="carnitine C22:6 transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (126129.1) or (1375.3) or (1374.1) or (1375.2) or (1375.1) or (1375.4)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_c226coa_c" stoichiometry="1"/>          <speciesReference species="M_crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_c226crn_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C226CPT2" name="C226 transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_c226crn_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_c226coa_m" stoichiometry="1"/>          <speciesReference species="M_crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C226CRNt" name="C226 transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_c226crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_c226crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C3STDH1Pr" name="C-3 sterol dehydrogenase (4-methylzymosterol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (50814.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4mzym_DASH_int1_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4mzym_DASH_int2_r" stoichiometry="1"/>          <speciesReference species="M_co2_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C3STDH1r" name="C-3 sterol dehydrogenase (4-methylzymosterol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (50814.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4mzym_DASH_int1_r" stoichiometry="1"/>          <speciesReference species="M_nad_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4mzym_DASH_int2_r" stoichiometry="1"/>          <speciesReference species="M_co2_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadh_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C3STKR2r" name="C-3 sterol keto reductase (zymosterol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_zym_DASH_int2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_zymst_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C4STMO1r" name="C-4 sterol methyl oxidase (4,4-dimethylzymosterol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6307.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_44mzym_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="3"/>          <speciesReference species="M_nadph_r" stoichiometry="3"/>          <speciesReference species="M_o2_r" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4mzym_DASH_int1_r" stoichiometry="1"/>          <speciesReference species="M_h2o_r" stoichiometry="4"/>          <speciesReference species="M_nadp_r" stoichiometry="3"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C4STMO2Pr" name="C-4 methyl sterol oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (50814.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4mzym_DASH_int2_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_zym_DASH_int2_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_C4STMO2r" name="C-4 methyl sterol oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6307.1) or (50814.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4mzym_DASH_int2_r" stoichiometry="1"/>          <speciesReference species="M_nad_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadh_r" stoichiometry="1"/>          <speciesReference species="M_zym_DASH_int2_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CAATPS" name="Ca ATPase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (492.1) or (491.1) or (490.1) or (493.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_ca2_c" stoichiometry="2"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_ca2_e" stoichiometry="2"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CARVEOLte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_carveol_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_carveol_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CAT2p" name="catalase A, peroxisomal (ethanol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (847.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_etoh_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acald_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CATm" name="catalase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (847.1)</p>            <p>SUBSYSTEM: ROS Detoxification</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o2_m" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_m" stoichiometry="2"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CATp" name="catalase A, peroxisomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (847.1)</p>            <p>SUBSYSTEM: Miscellaneous</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o2_x" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_x" stoichiometry="2"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CAt7r" name="calcium / sodium antiporter (1:3), reversible" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6547.6) or (6547.4) or (6547.2) or (6546.1) or (6547.1) or (6547.5) or (6543.1) or (6547.3)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ca2_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ca2_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="3"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CBPS" name="carbamoyl-phosphate synthase (glutamine-hydrolysing)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (790.1)</p>            <p>SUBSYSTEM: Pyrimidine Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="2"/>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="2"/>          <speciesReference species="M_cbp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CBPSam" name="carbamoyl-phosphate synthase (ammonia) (mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1373.1) or (1373.2)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="2"/>          <speciesReference species="M_hco3_m" stoichiometry="1"/>          <speciesReference species="M_nh4_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="2"/>          <speciesReference species="M_cbp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CBR2" name="Carbonyl reductase [NADPH] 1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (873.1)</p>            <p>SUBSYSTEM: Eicosanoid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_prostge2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_prostgf2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CDIPTr" name="phosphatidylinositol synthase (Homo sapiens)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10423.1) or (10423.2)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cdpdag_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_inost_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cmp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CDPDAGtm" name="intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cdpdag_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdpdag_DASH_hs_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CDSm" name="phosphatidate cytidylyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8760.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ctp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_pa_DASH_hs_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdpdag_DASH_hs_m" stoichiometry="1"/>          <speciesReference species="M_ppi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CEPTC" name="choline phosphotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10390.1) or (56994.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cdpchol_c" stoichiometry="1"/>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cmp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pchol_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CEPTE" name="ethanolamine phosphotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10390.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cdpea_c" stoichiometry="1"/>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cmp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pe_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CERK" name="Ceramide kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (64781.1) or (64781.2)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_crm_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_crmp_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CERT1rt" name="ceramide transport protein" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10087.1)</p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crm_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crm_DASH_hs_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CERT2rt" name="ceramide transport protein" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10087.1)</p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gluside_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gluside_DASH_hs_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CGLYt3_LPAREN_2_RPAREN_" name="Cys-Gly transport in via proton symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6565.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cgly_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cgly_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CH25H" name="cholesterol 25-hydroxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9023.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chsterol_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_xol25oh_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHLPCTD" name="choline phosphate cytididyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5130.1) or (9468.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cholp_c" stoichiometry="1"/>          <speciesReference species="M_ctp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdpchol_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHOLATEt" name="cholate transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6579.1) or (10599.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cholate_e" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cholate_c" stoichiometry="1"/>          <speciesReference species="M_hco3_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHOLATEt2" name="cholate transport via sodium cotransport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6554.1) or (6555.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cholate_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cholate_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHOLATEt3" name="ABC bile acid transporter" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8714.3) or (8647.1) or (8714.2) or (8714.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_cholate_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_cholate_e" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHOLD2m" name="choline dehydrogenase (FAD acceptor), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55349.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chol_m" stoichiometry="1"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_betald_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHOLPtl" name="choline phosphate intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cholp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cholp_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHOLtr" name="choline intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chol_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chol_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHSTEROLSULT" name="steroid sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6820.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chsterol_c" stoichiometry="1"/>          <speciesReference species="M_paps_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chsterols_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHSTEROLt" name="cholesterol efflux (ATP depedent)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (19.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_chsterol_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_chsterol_e" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHSTEROLt2" name="cholesterol intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chsterol_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chsterol_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CHSTEROLt3" name="cholesterol intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chsterol_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chsterol_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CITL" name="Citrate lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (171425.1) or (171425.2)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cit_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ac_c" stoichiometry="1"/>          <speciesReference species="M_oaa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CITRtm" name="citrulline mitochondrial transport via proton antiport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (83884.1) or (10166.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_citr_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_citr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CITt4_4" name="citrate transport via sodium symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (284111.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cit_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cit_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="4"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CITtam" name="citrate transport, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6576.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cit_c" stoichiometry="1"/>          <speciesReference species="M_mal_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cit_m" stoichiometry="1"/>          <speciesReference species="M_mal_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CITtbm" name="citrate transport, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6576.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cit_c" stoichiometry="1"/>          <speciesReference species="M_pep_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cit_m" stoichiometry="1"/>          <speciesReference species="M_pep_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CK" name="ATP Creatine kinase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1159.1) or (1160.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_creat_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_pcreat_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CKc" name="ATP Creatine kinase (c)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1152.1) or (1158.1) and (1152.1) or (1158.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_creat_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_pcreat_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CLHCOtex" name="chloride transport via bicarbonate countertransport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (116369.1) or (5172.1) or (116369.2) or (115019.2) or (1811.1) or (115019.1) or (1836.1) or (115111.1) or (115111.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cl_e" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cl_c" stoichiometry="1"/>          <speciesReference species="M_hco3_e" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CLPNDt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_clpnd_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_clpnd_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CO2ter" name="CO2 endoplasmic reticular transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_co2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CO2tp" name="CO2 peroxisomal transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_co2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_COAtm" name="CoA transporter" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8034.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_COAtp" name="coenzyme A transport, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_COUMARINte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coumarin_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coumarin_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_COt" name="CO transporter via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_co_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CPPPGO" name="coproporphyrinogen oxidase (O2 required)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1371.1)</p>            <p>SUBSYSTEM: Heme Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cpppg3_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="2"/>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_pppg9_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CREATt4_LPAREN_2_RPAREN_r" name="Creatine transport (sodium symport) (2:1)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6535.1) or (6537.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_creat_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_creat_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CREATtmdiffir" name="Creatine transport to/from mitochondria via diffusion" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_creat_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_creat_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CRMPte" name="crmp hs transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crmp_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crmp_DASH_hs_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CRNCAR3tp" name="carnitine-propcarnitine carrier, peroxisomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_pcrn_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_x" stoichiometry="1"/>          <speciesReference species="M_pcrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CRNCARtp" name="carnitine-acetylcarnitine carrier, peroxisomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acrn_x" stoichiometry="1"/>          <speciesReference species="M_crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acrn_c" stoichiometry="1"/>          <speciesReference species="M_crn_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CRNtim" name="L-carnitine transport out of mitochondria via diffusion" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CSNAT2m" name="carnitine O-aceyltransferase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1384.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_pcrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_ppcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CSNAT3x" name="carnitine O-aceyltransferase, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1384.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_x" stoichiometry="1"/>          <speciesReference species="M_ppcoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_pcrn_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CSNATm" name="carnitine O-aceyltransferase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1384.1)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acrn_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CSNATp" name="carnitine O-acetyltransferase, reverse direction, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1384.2)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_crn_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acrn_x" stoichiometry="1"/>          <speciesReference species="M_coa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CSm" name="citrate synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1431.1) or (1431.2)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_oaa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cit_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CTPS1" name="CTP synthase (NH3)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1503.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>          <speciesReference species="M_utp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_ctp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CTPS2" name="CTP synthase (glutamine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (56474.1) or (56474.2)</p>            <p>SUBSYSTEM: Pyrimidine Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_utp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_ctp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYANSTm" name="Cyanide sulfurtransferase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7263.1)</p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cyan_m" stoichiometry="1"/>          <speciesReference species="M_tsul_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_so3_m" stoichiometry="1"/>          <speciesReference species="M_tcynt_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYANt" name="Cyanide transport via diffusion (extracellular to cytosol)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cyan_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cyan_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYANtm" name="Cyanide transport via diffusion (mitochondrial)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cyan_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cyan_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYOOm3" name="cytochrome c oxidase, mitochondrial Complex IV" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1351.1) and (1329.1) and (1347.1) and (1327.1) and (9167.1) and (341947.1) and (4512.1) and (1350.1) and (1349.1) and (1339.1) and (4513.1) and (9377.1) and (1345.1) and (125965.1) and (4514.1) and (170712.1) and (1346.1) and (1340.1) and (1337.1) and (84701.1)</p>            <p>SUBSYSTEM: Oxidative Phosphorylation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_focytC_m" stoichiometry="4"/>          <speciesReference species="M_h_m" stoichiometry="7.92"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ficytC_m" stoichiometry="4"/>          <speciesReference species="M_h2o_m" stoichiometry="1.96"/>          <speciesReference species="M_h_c" stoichiometry="4"/>          <speciesReference species="M_o2s_m" stoichiometry="0.02"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYOR_u10m" name="ubiquinol-6 cytochrome c reductase, Complex III" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7384.1) and (7388.1) and (29796.1) and (10975.1) and (4519.1) and (7385.1) and (7386.1) and (1537.1) and (27089.1) and (7381.1) or (7384.1) and (7388.1) and (4519.1) and (10975.1) and (29796.2) and (7385.1) and (1537.1) and (7386.1) and (27089.1) and (7381.1)</p>            <p>SUBSYSTEM: Oxidative Phosphorylation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ficytC_m" stoichiometry="2"/>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_q10h2_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_focytC_m" stoichiometry="2"/>          <speciesReference species="M_h_c" stoichiometry="4"/>          <speciesReference species="M_q10_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYSALANaEx" name="L-alanine/L-cysteine Na-dependent exchange (Cys-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_cys_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYSAMO" name="Cysteamine oxygenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Taurine and hypotaurine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cysam_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_hyptaur_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYSO" name="cysteine oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1036.1)</p>            <p>SUBSYSTEM: Taurine and hypotaurine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3sala_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYSSERNaEx" name="L-serine/L-cysteine Na-dependent exchange (Cys-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cys_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYSTA" name="cysteine transaminase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2805.1)</p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_c" stoichiometry="1"/>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_mercppyr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYSTGL" name="cystathionine g-lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1491.1) or (1491.2)</p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cyst_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2obut_c" stoichiometry="1"/>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYSTHRNaEx" name="L-cysteine/L-threonine Na-dependent exchange (Cys-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cys_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYSTS" name="cystathionine beta-synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (875.1)</p>            <p>SUBSYSTEM: Methionine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hcys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cyst_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTD" name="cytidine deaminase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (978.1) or (57379.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cytd_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nh4_c" stoichiometry="1"/>          <speciesReference species="M_uri_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTDK1" name="cytidine kinase (ATP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7371.1) or (83549.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_cytd_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_cmp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTDK2m" name="cytidine kinase (ATP), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_cytd_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_cmp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTDt" name="cytidine facilated transport in cytosol" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3177.1) or (2030.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cytd_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cytd_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTDt4" name="cytidine transport in via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9154.1) or (9154.2) or (64078.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cytd_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cytd_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTDtm" name="cytidine facilated transport in mitochondria" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2030.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cytd_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cytd_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK1" name="cytidylate kinase (CMP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_cmp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_cdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK10" name="cytidylate kinase (CMP,dGTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_c" stoichiometry="1"/>          <speciesReference species="M_dgtp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_c" stoichiometry="1"/>          <speciesReference species="M_dgdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK10n" name="cytidylate kinase (CMP,dGTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_n" stoichiometry="1"/>          <speciesReference species="M_dgtp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_n" stoichiometry="1"/>          <speciesReference species="M_dgdp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK11" name="cytidylate kinase (dCMP,dGTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcmp_c" stoichiometry="1"/>          <speciesReference species="M_dgtp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>          <speciesReference species="M_dgdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK11n" name="cytidylate kinase (dCMP,dGTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcmp_n" stoichiometry="1"/>          <speciesReference species="M_dgtp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_n" stoichiometry="1"/>          <speciesReference species="M_dgdp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK12" name="cytidylate kinase (dCMP,dCTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcmp_c" stoichiometry="1"/>          <speciesReference species="M_dctp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK12n" name="cytidylate kinase (dCMP,dCTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcmp_n" stoichiometry="1"/>          <speciesReference species="M_dctp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_n" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK13" name="cytidylate kinase (dCMP,dATP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_datp_c" stoichiometry="1"/>          <speciesReference species="M_dcmp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dadp_c" stoichiometry="1"/>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK13n" name="cytidylate kinase (dCMP,dATP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_datp_n" stoichiometry="1"/>          <speciesReference species="M_dcmp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dadp_n" stoichiometry="1"/>          <speciesReference species="M_dcdp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK14" name="cytidylate kinase (dCMP,UTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcmp_c" stoichiometry="1"/>          <speciesReference species="M_utp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK14n" name="cytidylate kinase (dCMP,CTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcmp_n" stoichiometry="1"/>          <speciesReference species="M_utp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_n" stoichiometry="1"/>          <speciesReference species="M_udp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK1m" name="cytidylate kinase (CMP),mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_cmp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_cdp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK1n" name="cytidylate kinase (CMP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_cmp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_cdp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK2" name="cytidylate kinase (dCMP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dcmp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK2n" name="cytidylate kinase (dCMP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_dcmp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_dcdp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK3n" name="cytidylate kinase (dCMP,CTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ctp_n" stoichiometry="1"/>          <speciesReference species="M_dcmp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_n" stoichiometry="1"/>          <speciesReference species="M_dcdp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK4n" name="cytidylate kinase (dCMP,GTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcmp_n" stoichiometry="1"/>          <speciesReference species="M_gtp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_n" stoichiometry="1"/>          <speciesReference species="M_gdp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK5" name="cytidylate kinase (dCMP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ctp_c" stoichiometry="1"/>          <speciesReference species="M_dcmp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_c" stoichiometry="1"/>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK5n" name="cytidylate kinase (CMP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_n" stoichiometry="1"/>          <speciesReference species="M_gtp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_n" stoichiometry="1"/>          <speciesReference species="M_gdp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK6" name="cytidylate kinase (CMP,CTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_c" stoichiometry="1"/>          <speciesReference species="M_ctp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK6n" name="cytidylate kinase (CMP,CTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_n" stoichiometry="1"/>          <speciesReference species="M_ctp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_n" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK7" name="cytidylate kinase (CMP,UTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_c" stoichiometry="1"/>          <speciesReference species="M_utp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK7n" name="cytidylate kinase (CMP,UTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_n" stoichiometry="1"/>          <speciesReference species="M_utp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_n" stoichiometry="1"/>          <speciesReference species="M_udp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK8" name="cytidylate kinase (CMP,dATP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_c" stoichiometry="1"/>          <speciesReference species="M_datp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_c" stoichiometry="1"/>          <speciesReference species="M_dadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK8n" name="cytidylate kinase (CMP,dATP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_n" stoichiometry="1"/>          <speciesReference species="M_datp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_n" stoichiometry="1"/>          <speciesReference species="M_dadp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK9" name="cytidylate kinase (CMP,dCTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_c" stoichiometry="1"/>          <speciesReference species="M_dctp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_c" stoichiometry="1"/>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_CYTK9n" name="cytidylate kinase (CMP,dCTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_n" stoichiometry="1"/>          <speciesReference species="M_dctp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_n" stoichiometry="1"/>          <speciesReference species="M_dcdp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DADA" name="Deoxyadenosine deaminase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (100.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dad_DASH_DASH_DASH_2_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_din_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DADNK" name="deoxyadenosine kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dad_DASH_DASH_DASH_2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_damp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DAGKn_hs" name="Diacylglycerol phosphate kinase (homo sapiens)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8525.1) or (9162.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_dag_DASH_hs_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_h_n" stoichiometry="1"/>          <speciesReference species="M_pa_DASH_hs_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DALAOXx" name="D-Alanine Oxidase (x)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1610.1)</p>            <p>SUBSYSTEM: D-alanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_D_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_nh4_x" stoichiometry="1"/>          <speciesReference species="M_pyr_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DALAxt" name="D-Alanine transport to perixosome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: D-alanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_D_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DASCBR" name="dehydroascorbate reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2745.1) or (51022.2) or (51022.1)</p>            <p>SUBSYSTEM: Ascorbate and Aldarate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhdascb_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ascb_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DATPtn" name="dATP diffusion in nucleus" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_datp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_datp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DCK1n" name="Deoxycytidine kinase, nuclear (ATP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1633.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_dcyt_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_dcmp_n" stoichiometry="1"/>          <speciesReference species="M_h_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DCK2n" name="Deoxycytidine kinase, nuclear (UTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1633.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcyt_n" stoichiometry="1"/>          <speciesReference species="M_utp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcmp_n" stoichiometry="1"/>          <speciesReference species="M_h_n" stoichiometry="1"/>          <speciesReference species="M_udp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DCMPDA" name="dCMP deaminase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1635.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcmp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dump_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DCSPTN1CPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_dcsptn1coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_dcsptn1crn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DCSPTN1CPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_dcsptn1crn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_dcsptn1coa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DCSPTN1CRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcsptn1crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcsptn1crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DCSPTN1t" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcsptn1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcsptn1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DCYTD" name="deoxycytidine deaminase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (978.1) or (57379.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcyt_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_duri_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DEBRISOQUINEt" name="debrisoquine uniport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6582.1) or (6582.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_debrisoquine_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_debrisoquine_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DESAT16_2" name="palmitoyl-CoA desaturase (n-C16:0CoA -&gt; n-C16:1CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6319.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_pmtcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_hdcoa_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DESAT18_3" name="stearoyl-CoA desaturase (n-C18:0CoA -&gt; n-C18:1CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6319.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_stcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_odecoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DESAT18_4" name="stearoyl-CoA desaturase (n-C18:0CoA -&gt; n-C18:1CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6319.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_stcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_vacccoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DESAT18_5" name="stearoyl-CoA desaturase (n-C18:0CoA -&gt; n-C18:1CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6319.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_stcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_od2coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DESAT20_1" name="fatty acyl-CoA desaturase (n-C20:3CoA -&gt; n-C20:4CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3992.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dlnlcgcoa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arachdcoa_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DESAT20_2" name="fatty acyl-CoA desaturase (n-C20:4CoA -&gt; n-C20:5CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3992.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_eicostetcoa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_tmndnccoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DESAT22_2p" name="fatty acyl-CoA desaturase (n-C22:5CoA -&gt; n-C22:6CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_clpndcoa_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_c226coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="2"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DGAT" name="diacylglycerol acyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8694.1) or (84649.1)</p>            <p>SUBSYSTEM: Triacylglycerol Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal3coa_c" stoichiometry="1"/>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_tag_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DGCHOLte" name="bile acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dgchol_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dgchol_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DGCHOLtx" name="bile acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dgchol_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dgchol_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DGK1" name="deoxyguanylate kinase (dGMP:ATP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2987.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dgmp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_dgdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DGK2m" name="deoxyguanylate kinase (dGMP:dATP) (mitochondrial)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_datp_m" stoichiometry="1"/>          <speciesReference species="M_dgmp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dadp_m" stoichiometry="1"/>          <speciesReference species="M_dgdp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DGNSKm" name="deoxyguanosine kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1716.5) or (1716.1) or (1716.4) or (1716.2) or (1716.3)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_dgsn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_dgmp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DGSNtm" name="deoyguanosine transport in mitochondria" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dgsn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dgsn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DGULND" name="dehydro-L-gulonate decarboxylase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Pentose and Glucuronate Interconversions</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3dhguln_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_xylu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHAAt1r" name="dehydroascorbate transport (uniport)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6515.1) or (6513.1) or (6517.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhdascb_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhdascb_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHCHOLESTANATEtm" name="lipid, flip-flop intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhcholestanate_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhcholestanate_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHCR241r" name=" 24-dehydrocholesterol reductase [Precursor]" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1718.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fadh2_r" stoichiometry="1"/>          <speciesReference species="M_zymst_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fad_r" stoichiometry="1"/>          <speciesReference species="M_zymstnl_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHCR242r" name=" 24-dehydrocholesterol reductase [Precursor]" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1718.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chlstol_r" stoichiometry="1"/>          <speciesReference species="M_fadh2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fad_r" stoichiometry="1"/>          <speciesReference species="M_lthstrl_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHCR243r" name=" 24-dehydrocholesterol reductase [Precursor]" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1718.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dsmsterol_r" stoichiometry="1"/>          <speciesReference species="M_fadh2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chsterol_r" stoichiometry="1"/>          <speciesReference species="M_fad_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHCR71r" name=" 7-dehydrocholesterol reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1717.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ddsmsterol_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dsmsterol_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHCR72r" name=" 7-dehydrocholesterol reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1717.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7dhchsterol_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chsterol_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHCRD1" name="dihydroceramide desaturase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8560.1) or (8560.2)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhcrm_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crm_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHCRD2" name="dihydroceramide desaturase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8560.1) or (8560.2)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhcrm_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_fad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crm_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_fadh2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHEASULT" name="Dehydroepiandrosterone sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6783.1) or (6822.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhea_c" stoichiometry="1"/>          <speciesReference species="M_paps_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dheas_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHFR" name="dihydrofolate reductase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1719.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhf_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHFtl" name="dihydrofolate reversible lysosomal transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhf_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHORD9" name="dihydoorotic acid dehydrogenase (quinone10)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1723.1)</p>            <p>SUBSYSTEM: Pyrimidine Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhor_DASH_DASH_DASH_S_c" stoichiometry="1"/>          <speciesReference species="M_q10_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_orot_c" stoichiometry="1"/>          <speciesReference species="M_q10h2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHORTS" name="dihydroorotase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (790.1)</p>            <p>SUBSYSTEM: Pyrimidine Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhor_DASH_DASH_DASH_S_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cbasp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHPM1" name="dihydropyrimidinase (5,6-dihydrouracil)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1807.1) or (1809.1) or (1808.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_56dura_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cala_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHPM2" name="dihydropyrimidinase (dihydrothymine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_56dthm_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3uib_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DHPR" name=" 6,7-dihydropteridine reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5860.1)</p>            <p>SUBSYSTEM: Tetrahydrobiopterin</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhbpt_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_thbpt_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DIDPtn" name="dIDP nuclear transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_didp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_didp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DITPtn" name="dITP nuclear transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ditp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ditp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DKMPPD" name=" 2,3-diketo-5-methylthio-1-phosphopentane degradation reaction" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dkmpp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2kmb_c" stoichiometry="1"/>          <speciesReference species="M_for_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DLNLCGCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_dlnlcgcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_dlnlcgcrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DLNLCGCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_dlnlcgcrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_dlnlcgcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DLNLCGCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dlnlcgcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dlnlcgcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DLNLCGt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dlnlcg_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dlnlcg_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DMANTIPYRINEte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dmantipyrine_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dmantipyrine_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DMATTx" name="dimethylallyltranstransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2224.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dmpp_x" stoichiometry="1"/>          <speciesReference species="M_ipdp_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_grdp_x" stoichiometry="1"/>          <speciesReference species="M_ppi_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DMGDHm" name="dimethylglycine dehydrogenase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (29958.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dmgly_m" stoichiometry="1"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>          <speciesReference species="M_fald_m" stoichiometry="1"/>          <speciesReference species="M_sarcs_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DMGtm" name="dimethylglycine transport via diffusion (cytosol to mitochondria)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dmgly_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dmgly_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DM_Asn_X_Ser_FSLASH_Thr_LPAREN_ly_RPAREN_" name="DM Asn-X-Ser/Thr(ly)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Asn_DASH_DASH_DASH_X_DASH_DASH_DASH_Ser_DASH_FSLASH_DASH_Thr_l" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DM_datp_LPAREN_n_RPAREN_" name="DM datp(n)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_datp_n" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DM_dctp_LPAREN_m_RPAREN_" name="dCTP demand" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dctp_m" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DM_dttp_LPAREN_n_RPAREN_" name="DM dttp(n)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dttp_n" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DM_ethamp_LPAREN_r_RPAREN_" name="Ethanolamine phosphate demand" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ethamp_r" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DM_kdn_c" name="DM kdn(c)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_kdn_c" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DM_sprm_c" name="DM sprm(c)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_sprm_c" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DNADDP" name="Deaminido NAD diphosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5167.1) or (5169.1) or (5168.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dnad_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nicrnt_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DNADtn" name="dNAD transport, nuclear trhough pore" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dnad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dnad_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DNDPt26m" name="dCDP transport via dUDP antiport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (60386.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>          <speciesReference species="M_dudp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_m" stoichiometry="1"/>          <speciesReference species="M_dudp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DNDPt27m" name="dCDP transport via dTDP antiport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (60386.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>          <speciesReference species="M_dtdp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_m" stoichiometry="1"/>          <speciesReference species="M_dtdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DNDPt31m" name="dCDP transport via ATP antiport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (60386.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dcdp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DNDPt41m" name="dUTP transport via dCDP antiport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (60386.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcdp_m" stoichiometry="1"/>          <speciesReference species="M_dutp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>          <speciesReference species="M_dutp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DNDPt50m" name="dTTP transport via dCDP antiport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (60386.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcdp_m" stoichiometry="1"/>          <speciesReference species="M_dttp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>          <speciesReference species="M_dttp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DNDPt53m" name="dCTP transport via dGDP antiport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (60386.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dctp_c" stoichiometry="1"/>          <speciesReference species="M_dgdp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dctp_m" stoichiometry="1"/>          <speciesReference species="M_dgdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DNDPt58m" name="dGTP transport via ADP antiport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (60386.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_dgtp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_dgtp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOLGLCP_Lter" name="Dolichyl beta-D-glucosyl phosphate flippase (liver)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: N-Glycan Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dolglcp_DASH_L_c" stoichiometry="0.1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dolglcp_DASH_L_r" stoichiometry="0.1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOLGLCP_Uter" name="Dolichyl beta-D-glucosyl phosphate flippase (uterus)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: N-Glycan Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dolglcp_DASH_U_c" stoichiometry="0.1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dolglcp_DASH_U_r" stoichiometry="0.1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOLGPP_Ler" name="Dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase (liver)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: N-Glycan Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dolglcp_DASH_L_r" stoichiometry="0.1"/>          <speciesReference species="M_h2o_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dolp_DASH_L_r" stoichiometry="0.1"/>          <speciesReference species="M_glc_DASH_DASH_DASH_D_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOLGPP_Uer" name="Dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase (uterus)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: N-Glycan Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dolglcp_DASH_U_r" stoichiometry="0.1"/>          <speciesReference species="M_h2o_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dolp_DASH_U_r" stoichiometry="0.1"/>          <speciesReference species="M_glc_DASH_DASH_DASH_D_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOLP_Lter" name="dolichol phosphate flippase (liver)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: N-Glycan Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dolp_DASH_L_r" stoichiometry="0.1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dolp_DASH_L_c" stoichiometry="0.1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOLP_Uter" name="dolichol phosphate flippase (uterus)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: N-Glycan Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dolp_DASH_U_r" stoichiometry="0.1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dolp_DASH_U_c" stoichiometry="0.1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOPABMO" name="dopamine beta-monooxygenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (26002.1) or (1621.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ascb_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_dopa_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhdascb_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nrpphr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOPASFt" name="Dopamine 3-0-sulfate transport (diffusion)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dopasf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dopasf_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOPASULT" name="Dopamine Sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6799.1) or (6817.3) or (6799.2) or (6818.2) or (6817.2) or (6818.1) or (6817.1) or (6817.4) or (6818.3) or (6817.5)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dopa_c" stoichiometry="1"/>          <speciesReference species="M_paps_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dopasf_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOPAVESSEC" name="Dopamine secretion via secretory vesicle (ATP driven)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6570.1) or (6571.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="2"/>          <speciesReference species="M_dopa_c" stoichiometry="3"/>          <speciesReference species="M_h2o_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="2"/>          <speciesReference species="M_dopa_e" stoichiometry="3"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_pi_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DOPAtu" name="Dopamine uniport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6581.1) or (6582.2) or (6582.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dopa_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dopa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DPGM" name="Diphosphoglyceromutase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (669.1) or (5223.1) or (5224.2) or (5224.1) or (669.2)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_13dpg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_23dpg_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DPGase" name="Diphosphoglycerate phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (669.2) or (5223.1) or (5224.2) or (5224.1) or (669.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_23dpg_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3pg_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DPMVDx" name="diphosphomevalonate decarboxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4597.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5dpmev_x" stoichiometry="1"/>          <speciesReference species="M_atp_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_x" stoichiometry="1"/>          <speciesReference species="M_co2_x" stoichiometry="1"/>          <speciesReference species="M_ipdp_x" stoichiometry="1"/>          <speciesReference species="M_pi_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DRBK" name="Deoxyribokinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (64080.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_drib_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2dr5p_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DRPA" name="deoxyribose-phosphate aldolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2dr5p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acald_c" stoichiometry="1"/>          <speciesReference species="M_g3p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DSAT" name="dihydrosphingosine N-acyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotalcoa_c" stoichiometry="1"/>          <speciesReference species="M_sphgn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_dhcrm_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DTDPtn" name="dTDP nuclear transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dtdp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dtdp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DTMPK" name="dTMP kinase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1841.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dtmp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_dtdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DUDPtn" name="dUDP nuclear transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dudp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dudp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DUMPtn" name="dUMP nuclear transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dump_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dump_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DURAD" name="dihydrouracil dehydrogenase (NADP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1806.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_56dura_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_ura_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DURAD2" name="dihydrothymin dehydrogenase (NADP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1806.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_56dthm_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_thym_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DURIK1" name="deoxyuridine kinase (ATP:Deoxyuridine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7083.1) or (7084.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_duri_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_dump_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DURIK1m" name="deoxyuridine kinase (ATP:Deoxyuridine), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7084.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_duri_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_dump_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DURIPP" name="deoxyuridine phosphorylase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4860.1) or (151531.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_duri_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2dr1p_c" stoichiometry="1"/>          <speciesReference species="M_ura_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DUTPDPm" name="dUTP diphosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1854.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dutp_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dump_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_ppi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_DUTPDPn" name="dUTP diphosphatase, nuclear" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1854.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dutp_n" stoichiometry="1"/>          <speciesReference species="M_h2o_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dump_n" stoichiometry="1"/>          <speciesReference species="M_h_n" stoichiometry="1"/>          <speciesReference species="M_ppi_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_D_3AIBt" name="D-3-amino-isobutyrate transport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3aib_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3aib_DASH_DASH_DASH_D_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_D_LACt2" name="D-lactate transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9194.1) or (23539.1) or (6566.1) or (9123.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_lac_DASH_DASH_DASH_D_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lac_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EAFLATOXINte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_eaflatoxin_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_eaflatoxin_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EBASTINEOHte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ebastineoh_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ebastineoh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EBASTINEOHtr" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ebastineoh_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ebastineoh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EBASTINEte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ebastine_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ebastine_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EBASTINEtr" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ebastine_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ebastine_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EBP1r" name=" 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10682.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_zymst_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chlstol_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EBP2r" name=" 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10682.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_zymstnl_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lthstrl_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ECOAH12m" name=" 3-hydroxyacyl-CoA dehydratase (3-hydroxyisobutyryl-CoA) (mitochondria)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1892.1) or (3030.1) and (3032.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2mp2coa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3hibutcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ECOAH1m" name=" 3-hydroxyacyl-CoA dehydratase (3-hydroxybutanoyl-CoA) (mitochondria)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (549.1) or (3030.1) and (3032.1) or (1892.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3hbcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_b2coa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ECOAH9m" name=" 2-Methylprop-2-enoyl-CoA (2-Methylbut-2-enoyl-CoA), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1892.1) or (3030.1) and (3032.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2mb2coa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3hmbcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EICOSTETCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_eicostetcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_eicostetcrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EICOSTETCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_eicostetcrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_eicostetcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EICOSTETCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_eicostetcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_eicostetcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EICOSTETt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_eicostet_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_eicostet_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ELAIDCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_od2coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_elaidcrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ELAIDCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_elaidcrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_od2coa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ELAIDCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_elaidcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_elaidcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ELAIDt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_elaid_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_elaid_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ENGASE2ly" name="endo-beta-N-acetylglucosaminidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="1"/>          <speciesReference species="M_n2m2nm_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam_l" stoichiometry="1"/>          <speciesReference species="M_n2m2nmn_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ENGASEly" name="endo-beta-N-acetylglucosaminidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="1"/>          <speciesReference species="M_s2l2n2m2m_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam_l" stoichiometry="1"/>          <speciesReference species="M_s2l2n2m2mn_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ENO" name="enolase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2023.1) or (26237.1) or (2027.2) or (2027.1) or (2026.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2pg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pep_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ESTRADIOLGLCt" name="estradiol glucuronide transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (28234.1) or (28231.1) or (10599.1) or (6579.1) or (53919.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estradiolglc_e" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estradiolglc_c" stoichiometry="1"/>          <speciesReference species="M_hco3_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ESTRADIOLGLCtr" name="glucuronidated compound transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estradiolglc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estradiolglc_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ESTRADIOLtr" name="estradiol intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estradiol_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estradiol_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ESTRONEGLCt" name="ABC transporter" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8714.1) or (8714.3) or (8714.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_estroneglc_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_estroneglc_e" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ESTRONEGLCtr" name="glucuronidated compound transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estroneglc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estroneglc_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ESTRONESt" name="estrone 3-sulfate transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11309.1) or (10599.1) or (53919.1) or (6579.1) or (28232.1) or (28231.1) or (28234.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estrones_e" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estrones_c" stoichiometry="1"/>          <speciesReference species="M_hco3_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ESTRONESt2" name="estrone-3-sulfate transport via sodium cotransport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6554.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estrones_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estrones_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ESTRONEtr" name="estrone intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estrone_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estrone_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ESTSULT" name="Estrogen sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6783.1) or (6817.4) or (6817.1) or (6817.3) or (6817.2) or (6817.5)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estrone_c" stoichiometry="1"/>          <speciesReference species="M_paps_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estrones_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ETF" name="electron transfer flavoprotein" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2109.2) and (2108.1) or (2109.1) and (2108.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_etfox_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_etfrd_m" stoichiometry="1"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ETFQO" name="Electron transfer flavoprotein-ubiquinone oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2110.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_etfrd_m" stoichiometry="1"/>          <speciesReference species="M_q10_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_etfox_m" stoichiometry="1"/>          <speciesReference species="M_q10h2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ETHAK" name="Ethanolamine kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1119.2) or (55500.1) or (1119.1) or (55224.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_etha_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_ethamp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ETOHMO" name="ethanol monooxygenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1571.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_etoh_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acald_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ETOHt" name="ethanol reversible transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_etoh_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_etoh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ETOHtx" name="ethanol reversible peroxisomal transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_etoh_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_etoh_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_10fthf7glu_LPAREN_e_RPAREN_" name=" 10-formyltetrahydrofolate-[Glu](7) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf7glu_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_10fthf_LPAREN_e_RPAREN_" name=" 10-Formyltetrahydrofolate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_13_cis_retnglc_LPAREN_e_RPAREN_" name=" 13-cis-retinoyl glucuronide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retnglc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_1mncam_LPAREN_e_RPAREN_" name=" 1-Methylnicotinamide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_1mncam_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_24nph_LPAREN_e_RPAREN_" name=" 2,4 dihydroxy nitrophenol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_24nph_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_25hvitd3_LPAREN_e_RPAREN_" name=" 25-Hydroxyvitamin D3 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_25hvitd3_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_2hb_LPAREN_e_RPAREN_" name=" 2-Hydroxybutyrate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2hb_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_2mcit_LPAREN_e_RPAREN_" name=" 2-Methylcitrate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2mcit_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_34dhoxpeg_LPAREN_e_RPAREN_" name=" 3,4-Dihydroxyphenylethyleneglycol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_34dhoxpeg_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_34dhphe_LPAREN_e_RPAREN_" name=" 3,4-Dihydroxy-L-phenylalanine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_34dhphe_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_3aib_D_LPAREN_e_RPAREN_" name="D-3-Amino-isobutanoate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3aib_DASH_DASH_DASH_D_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_3aib_LPAREN_e_RPAREN_" name="L-3-Amino-isobutanoate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3aib_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_3mlda_LPAREN_e_RPAREN_" name=" 3-Methylimidazoleacetic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3mlda_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_4hdebrisoquine_LPAREN_e_RPAREN_" name=" 4 hydroxy debrisoquine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4hdebrisoquine_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_4hphac_LPAREN_e_RPAREN_" name=" 4-Hydroxyphenylacetate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4hphac_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_4mtolbutamide_LPAREN_e_RPAREN_" name=" 4 hydroxy tolbutamide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4mtolbutamide_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_4nph_LPAREN_e_RPAREN_" name=" 4-Nitrophenol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4nph_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_4nphsf_LPAREN_e_RPAREN_" name=" 4-Nitrophenyl sulfate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4nphsf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_4pyrdx_LPAREN_e_RPAREN_" name=" 4-Pyridoxate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4pyrdx_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_5adtststerone_LPAREN_e_RPAREN_" name=" 5alpha-Dihydrotestosterone exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5adtststerone_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_5adtststeroneglc_LPAREN_e_RPAREN_" name=" 5alpha-Dihydrotestosterone glucuronide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5adtststeroneglc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_5adtststerones_LPAREN_e_RPAREN_" name=" 5alpha-Dihydrotestosterone sulfate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5adtststerones_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_5fthf_LPAREN_e_RPAREN_" name=" 5-Formyltetrahydrofolate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5fthf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_5homeprazole_LPAREN_e_RPAREN_" name=" 5 hydroxy omeprazole exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5homeprazole_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_7dhf_LPAREN_e_RPAREN_" name="heptaglutamyl folate (DHF) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7dhf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_7thf_LPAREN_e_RPAREN_" name="heptaglutamyl folate (THF) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7thf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_CLPND_LPAREN_e_RPAREN_" name="clupanodonic acid (docosapentaenoic (n-3)) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_clpnd_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_Rtotal2_LPAREN_e_RPAREN_" name="R total 2 position exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal2_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_Rtotal3_LPAREN_e_RPAREN_" name="R total 3 position exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal3_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_Rtotal_LPAREN_e_RPAREN_" name="R total exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_acac_LPAREN_e_RPAREN_" name="Acetoacetate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acac_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_acetone_LPAREN_e_RPAREN_" name="Acetone exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acetone_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_adp" name="adp exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adp_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_adrn_LPAREN_e_RPAREN_" name="adrenic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adrn_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_aflatoxin_LPAREN_e_RPAREN_" name="aflatoxin B1 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_aflatoxin_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ak2lgchol_hs_LPAREN_e_RPAREN_" name=" 1-alkyl 2-lysoglycerol 3-phosphocholine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ak2lgchol_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_antipyrene_LPAREN_e_RPAREN_" name="antipyrene exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_antipyrene_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_apnnox_LPAREN_e_RPAREN_" name="alpha-Pinene-oxide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_apnnox_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_appnn_LPAREN_e_RPAREN_" name="(+)-alpha-Pinene exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_appnn_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_arab_L_LPAREN_e_RPAREN_" name="L-Arabinose exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arab_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_arach_LPAREN_e_RPAREN_" name="Arachidic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arach_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_arg_L_LPAREN_e_RPAREN_" name="L-Arginine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arg_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_asn_L_LPAREN_e_RPAREN_" name="L-Asparagine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_asn_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_asp_L_LPAREN_e_RPAREN_" name="L-Aspartate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_asp_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_atp_LPAREN_e_RPAREN_" name="ATP exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_bhb_LPAREN_e_RPAREN_" name="(R)-3-Hydroxybutanoate transport via H+ symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bhb_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_bildglcur_LPAREN_e_RPAREN_" name="Bilirubin beta-diglucuronide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bildglcur_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_bilglcur_LPAREN_e_RPAREN_" name="Bilirubin monoglucuronide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bilglcur_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_bilirub_LPAREN_e_RPAREN_" name="Bilirubin exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bilirub_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_biocyt_LPAREN_e_RPAREN_" name="Biocytin exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_biocyt_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_btn_LPAREN_e_RPAREN_" name="Biotin exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_btn_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_but_LPAREN_e_RPAREN_" name="Butyrate (n-C4:0) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_but_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_carveol_LPAREN_e_RPAREN_" name="(E)-carveol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_carveol_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_cit_LPAREN_e_RPAREN_" name="Citrate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cit_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_cmp_LPAREN_e_RPAREN_" name="CMP exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_co_LPAREN_e_RPAREN_" name="Carbon monoxide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_co_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_coumarin_LPAREN_e_RPAREN_" name="coumarin exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coumarin_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_creat_LPAREN_e_RPAREN_" name="Creatine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_creat_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_crmp_hs_LPAREN_e_RPAREN_" name="Ceramide 1-phosphate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crmp_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_crvnc_LPAREN_e_RPAREN_" name="nC22:6 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crvnc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_cyan_LPAREN_e_RPAREN_" name="Hydrogen cyanide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cyan_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_dcsptn1_LPAREN_e_RPAREN_" name="docosa-4,7,10,13,16-pentaenoic acid (n-6) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcsptn1_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_debrisoquine_LPAREN_e_RPAREN_" name="debrisoquine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_debrisoquine_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_dgchol_LPAREN_e_RPAREN_" name="Chenodeoxyglycocholate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dgchol_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_dhf_LPAREN_e_RPAREN_" name=" 7,8-Dihydrofolate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_dlnlcg_LPAREN_e_RPAREN_" name="dihomo-gamma-linolenic acid (n-6) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dlnlcg_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_dmantipyrine_LPAREN_e_RPAREN_" name="demethylated antipyrine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dmantipyrine_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_dopasf_LPAREN_e_RPAREN_" name="Dopamine 3-O-sulfate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dopasf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_eaflatoxin_LPAREN_e_RPAREN_" name=" 8,9 epxoy aflatoxin B1 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_eaflatoxin_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ebastine_LPAREN_e_RPAREN_" name="ebastine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ebastine_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ebastineoh_LPAREN_e_RPAREN_" name="hydroxylated ebastine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ebastineoh_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_eicostet_LPAREN_e_RPAREN_" name="eicosatetranoic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_eicostet_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_elaid_LPAREN_e_RPAREN_" name="elaidic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_elaid_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_estradiolglc_LPAREN_e_RPAREN_" name="estradiol glucuronide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estradiolglc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_estroneglc_LPAREN_e_RPAREN_" name="estrone glucuronide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estroneglc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_estrones_LPAREN_e_RPAREN_" name="Estrone 3-sulfate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estrones_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_etoh_LPAREN_e_RPAREN_" name="Ethanol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_etoh_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_fe2_LPAREN_e_RPAREN_" name="Fe2+ exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fe2_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_fe3_LPAREN_e_RPAREN_" name="Fe3+ exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fe3_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_fol_LPAREN_e_RPAREN_" name="Folate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fol_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_fuc_L_LPAREN_e_RPAREN_" name="L-Fucose exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fuc_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_gam_LPAREN_e_RPAREN_" name="D-Glucosamine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gam_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_gchola_LPAREN_e_RPAREN_" name="glycocholate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gchola_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_gdchola_LPAREN_e_RPAREN_" name="glycochenodeoxycholate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gdchola_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_glc_LPAREN_e_RPAREN_" name="D-Glucose exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glc_DASH_DASH_DASH_D_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_glyb_LPAREN_e_RPAREN_" name="Glycine betaine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glyb_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_glyc_S_LPAREN_e_RPAREN_" name="(S)-Glycerate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glyc_DASH_DASH_DASH_S_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_glygn2_LPAREN_e_RPAREN_" name="glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]}) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glygn2_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_glygn4_LPAREN_e_RPAREN_" name="glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]}) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glygn4_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_gthox_LPAREN_e_RPAREN_" name="Oxidized glutathione exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthox_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_gthrd_LPAREN_e_RPAREN_" name="Reduced glutathione exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthrd_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_gtp_LPAREN_e_RPAREN_" name="GTP exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gtp_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_h2o2_LPAREN_e_RPAREN_" name="Hydrogen peroxide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o2_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ha_pre1_LPAREN_e_RPAREN_" name="hyaluronan biosynthesis, precursor 1 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ha_DASH_pre1_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_hcoumarin_LPAREN_e_RPAREN_" name="hydroxy coumarin exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hcoumarin_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_hdcea_LPAREN_e_RPAREN_" name="hexadecenoate (n-C16:1) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hdcea_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_hestratriol_LPAREN_e_RPAREN_" name=" 4,17 dihydroxy estradiol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hestratriol_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_hexc_LPAREN_e_RPAREN_" name="hexacosanoate (n-C26:0) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hexc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_his_L_LPAREN_e_RPAREN_" name="L-Histidine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_his_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_hpdca_LPAREN_e_RPAREN_" name="heptadecanoate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hpdca_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_htaxol_LPAREN_e_RPAREN_" name="hydroxylated taxol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_htaxol_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_idp_LPAREN_e_RPAREN_" name="IDP exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_idp_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ile_L_LPAREN_e_RPAREN_" name="L-Isoleucine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ile_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_imp_LPAREN_e_RPAREN_" name="IMP exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_imp_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_lac_D_LPAREN_e_RPAREN_" name="D-lactate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lac_DASH_DASH_DASH_D_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_leu_L_LPAREN_e_RPAREN_" name="L-Leucine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_leu_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_leuktrC4_LPAREN_e_RPAREN_" name="Leukotriene C4 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_leuktrC4_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_lgnc_LPAREN_e_RPAREN_" name="lignoceric acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lgnc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_limnen_LPAREN_e_RPAREN_" name="Limonene exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_limnen_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_lneldc_LPAREN_e_RPAREN_" name="linoelaidic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lneldc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_lnlc_LPAREN_e_RPAREN_" name="linoleic acid (all cis C18:2) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lnlc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_lnlnca_LPAREN_e_RPAREN_" name="alpha-Linolenic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lnlnca_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_lnlncg_LPAREN_e_RPAREN_" name="gamma-linolenic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lnlncg_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_lpchol_hs_LPAREN_e_RPAREN_" name="lysophosphatidylcholine (homo sapiens) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lpchol_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_malt_LPAREN_e_RPAREN_" name="Maltose exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_malt_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_mercplaccys_LPAREN_e_RPAREN_" name=" 3-mercaptolactate-cysteine disulfide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mercplaccys_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_met_L_LPAREN_e_RPAREN_" name="L-Methionine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_met_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_n2m2nmasn_LPAREN_e_RPAREN_" name="N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_n2m2nmasn_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_nac_LPAREN_e_RPAREN_" name="Nicotinate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nac_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_nh4_LPAREN_e_RPAREN_" name="Ammonia exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nh4_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_no_LPAREN_e_RPAREN_" name="Nitric oxide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_no_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_nrpphrsf_LPAREN_e_RPAREN_" name="Sulfate derivative of norepinephrine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nrpphrsf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_nrvnc_LPAREN_e_RPAREN_" name="nervonic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nrvnc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_o2s_LPAREN_e_RPAREN_" name="Superoxide anion exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2s_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ocdca_LPAREN_e_RPAREN_" name="octadecanoate (n-C18:0) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ocdca_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ocdcea_LPAREN_e_RPAREN_" name="octadecenoate (n-C18:1) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ocdcea_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_octa_LPAREN_e_RPAREN_" name="octanoate (n-C8:0) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_octa_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_omeprazole_LPAREN_e_RPAREN_" name="omeprazole exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_omeprazole_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_orn_LPAREN_e_RPAREN_" name="Ornithine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_orn_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_oxa_LPAREN_e_RPAREN_" name="Oxalate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_oxa_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_paf_hs_LPAREN_e_RPAREN_" name=" 1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_paf_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_pe_hs_LPAREN_e_RPAREN_" name="phosphatidylethanolamine (homo sapiens) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pe_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_perillyl_LPAREN_e_RPAREN_" name="Perillyl alcohol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_perillyl_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_phe_L_LPAREN_e_RPAREN_" name="L-Phenylalanine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_phe_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_pheacgln_LPAREN_e_RPAREN_" name="alpha-N-Phenylacetyl-L-glutamine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pheacgln_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_pi_LPAREN_e_RPAREN_" name="Phosphate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pi_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ppa_LPAREN_e_RPAREN_" name="Propionate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ppa_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_pro_L_LPAREN_e_RPAREN_" name="L-Proline exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pro_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_prostge2_LPAREN_e_RPAREN_" name="Prostaglandin E2 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_prostge2_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_prostgf2_LPAREN_e_RPAREN_" name="Prostaglandin F2alpha exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_prostgf2_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ps_hs_LPAREN_e_RPAREN_" name="phosphatidylserine (homo sapiens) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ps_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ptdca_LPAREN_e_RPAREN_" name="pentadecanoate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ptdca_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_pydam_LPAREN_e_RPAREN_" name="Pyridoxamine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pydam_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_pydxn_LPAREN_e_RPAREN_" name="Pyridoxine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pydxn_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_pyr_LPAREN_e_RPAREN_" name="Pyruvate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pyr_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_retn_LPAREN_e_RPAREN_" name="Retinoate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_retn_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_retnglc_LPAREN_e_RPAREN_" name="retinoyl glucuronide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_retnglc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_rib_D_LPAREN_e_RPAREN_" name="D-Ribose exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_rib_DASH_DASH_DASH_D_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_s2l2fn2m2masn_LPAREN_e_RPAREN_" name="PA6 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_s2l2fn2m2masn_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_sl_L_LPAREN_e_RPAREN_" name="L-sulfolactate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_sl_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_srtn_LPAREN_e_RPAREN_" name="Serotonin exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_srtn_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_strch1_LPAREN_e_RPAREN_" name="starch, structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]}) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_strch1_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_strch2_LPAREN_e_RPAREN_" name="starch, structure 2 (1,6-{2[1,4-Glc], [1,4-Glc]}) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_strch2_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_strdnc_LPAREN_e_RPAREN_" name="stearidonic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_strdnc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tag_hs_LPAREN_e_RPAREN_" name="triacylglycerol (homo sapiens) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tag_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tagat_D_LPAREN_e_RPAREN_" name="D-Tagatose exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tagat_DASH_DASH_DASH_D_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_taxol_LPAREN_e_RPAREN_" name="paclitaxel exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_taxol_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tchola_LPAREN_e_RPAREN_" name="Taurocholic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tchola_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tcynt_LPAREN_e_RPAREN_" name="Thiocyanate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tcynt_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tdchola_LPAREN_e_RPAREN_" name="taurochenodeoxycholate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tdchola_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tethex3_LPAREN_e_RPAREN_" name="tetracosahexaenoic acid, n-3 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tethex3_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tetpent3_LPAREN_e_RPAREN_" name="tetracosapentaenoic acid, n-3 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tetpent3_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tetpent6_LPAREN_e_RPAREN_" name="tetracosapentaenoic acid, n-6 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tetpent6_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tettet6_LPAREN_e_RPAREN_" name="tetracosatetraenoic acid n-6 exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tettet6_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_thf_LPAREN_e_RPAREN_" name=" 5,6,7,8-Tetrahydrofolate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_thm_LPAREN_e_RPAREN_" name="Thiamin exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thm_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_thmmp_LPAREN_e_RPAREN_" name="Thiamin monophosphate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thmmp_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_thmtp_LPAREN_e_RPAREN_" name="Thiamin triphosphate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thmtp_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_thr_L_LPAREN_e_RPAREN_" name="L-Threonine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thr_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_thymd_LPAREN_e_RPAREN_" name="Thymidine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thymd_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tmndnc_LPAREN_e_RPAREN_" name="timnodonic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tmndnc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tolbutamide_LPAREN_e_RPAREN_" name="tolbutamide exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tolbutamide_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_triodthy_LPAREN_e_RPAREN_" name="Triiodothyronine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_triodthy_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_triodthysuf_LPAREN_e_RPAREN_" name="Triiodothyronine sulfate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_triodthysuf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_trp_L_LPAREN_e_RPAREN_" name="L-Tryptophan exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_trp_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tsul_LPAREN_e_RPAREN_" name="Thiosulfate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tsul_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_ttdca_LPAREN_e_RPAREN_" name="tetradecanoate (n-C14:0) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ttdca_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_tymsf_LPAREN_e_RPAREN_" name="Tyramine O-sulfate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tymsf_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_urate_LPAREN_e_RPAREN_" name="Urate exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_urate_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_urea_LPAREN_e_RPAREN_" name="Urea exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_urea_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_utp_LPAREN_e_RPAREN_" name="UTP exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_utp_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_vacc_LPAREN_e_RPAREN_" name="vaccenic acid exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_vacc_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_val_L_LPAREN_e_RPAREN_" name="L-Valine exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_val_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_whhdca_LPAREN_e_RPAREN_" name="omega hydroxy hexadecanoate (n-C16:0) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_whhdca_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_whttdca_LPAREN_e_RPAREN_" name="omega hydroxy tetradecanoate (n-C14:0) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_whttdca_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_xolest2_hs_LPAREN_e_RPAREN_" name="cholesterol ester (from FULLR2) exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xolest2_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_xolest_hs_LPAREN_e_RPAREN_" name="cholesterol ester exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xolest_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_xoltri24_LPAREN_e_RPAREN_" name=" 7-alpha,24(S)-Dihydroxycholesterol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoltri24_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_xoltri25_LPAREN_e_RPAREN_" name=" 7-alpha,25-Dihydroxycholesterol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoltri25_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_EX_xoltri27_LPAREN_e_RPAREN_" name=" 7-alpha,27-Dihydroxycholesterol exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoltri27_e" stoichiometry="1"/>        </listOfReactants>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL140i" name="fatty-acid--CoA ligase (tetradecanoate)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2181.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_ttdca_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_tdcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL150" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22305.2) or (2182.1) or (2180.1) or (2181.2) or (2181.1) or (22305.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_ptdca_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_ptdcacoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL160i" name="C160 fatty acid activation" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2181.2) or (22305.2) or (51703.1) or (22305.1) or (2180.1) or (2181.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_hdca_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_pmtcoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL161" name="fatty-acid--CoA ligase (hexadecenoate)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_hdcea_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_hdcoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL170" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22305.2) or (2182.1) or (2180.1) or (2181.2) or (2181.1) or (22305.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_hpdca_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_hpdcacoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL180i" name="C180 fatty acid activation" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22305.2) or (2181.2) or (51703.1) or (2181.1) or (2180.1) or (22305.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_ocdca_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_stcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL1812" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_vacc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_vacccoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL1813" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_elaid_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_od2coa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL181i" name="C181 fatty acid activation" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1) or (2181.2) or (2181.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_ocdcea_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_odecoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL1821" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_lnlc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_lnlccoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL1822" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_lneldc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_lneldccoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL1831" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_lnlncg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_lnlncgcoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL1832" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_lnlnca_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_lnlncacoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL184" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_strdnc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_strdnccoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL191" name="fatty-acid--CoA ligase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11001.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_prist_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_pristcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL200" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arach_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_arachcoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL203" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_dlnlcg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_dlnlcgcoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL204" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachd_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_arachdcoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL2042" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_eicostet_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_eicostetcoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL204i" name="arachidonic acid activation" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22305.1) or (2181.2) or (2181.1) or (2180.1) or (22305.2) or (2182.1) or (2182.2)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachd_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_arachdcoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL205" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_tmndnc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_tmndnccoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL224" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adrn_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adrncoa_c" stoichiometry="1"/>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL2251" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_dcsptn1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_dcsptn1coa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL2252" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_clpnd_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_clpndcoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL226" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_crvnc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_c226coa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL240" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_lgnc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_lgnccoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL241" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_nrvnc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_nrvnccoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL244_1" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_tettet6_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_tettet6coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL245_1" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_tetpent6_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_tetpent6coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL245_2" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_tetpent3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_tetpent3coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL246_1" name="fatty-acid--CoA ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_tethex3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_tethex3coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL260" name="fatty-acid--CoA ligase (n-C26:0)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2180.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_hexc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_hexccoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL40im" name="fatty-acid--CoA ligase (butanoate), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (116285.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_but_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_m" stoichiometry="1"/>          <speciesReference species="M_btcoa_m" stoichiometry="1"/>          <speciesReference species="M_ppi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FACOAL80i" name="fatty-acid--CoA ligase (octanoate)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2181.1) or (2181.2)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_octa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_occoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FADDP" name="FAD diphosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5167.1)</p>            <p>SUBSYSTEM: Riboflavin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_fmn_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FADH2tru" name="FADH2 transporter, endoplasmic reticulum" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fadh2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fadh2_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FADH2tx" name="FADH2 transporter, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fadh2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fadh2_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FADtru" name="FAD transporter, endoplasmic reticulum" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fad_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FADtx" name="FAD transporter, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fad_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAH2" name="Fatty acid omega-hydroxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1579.1)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_ttdca_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_whttdca_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAH3" name="Fatty acid omega-hydroxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1579.1)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_hdca_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_whhdca_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FALDH" name="formaldehyde dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (128.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fald_c" stoichiometry="1"/>          <speciesReference species="M_gthrd_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Sfglutth_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FALDtm" name="formaldehyde transport via diffusion (mitochondrial)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fald_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fald_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC140" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="6"/>          <speciesReference species="M_fad_m" stoichiometry="6"/>          <speciesReference species="M_h2o_m" stoichiometry="6"/>          <speciesReference species="M_nad_m" stoichiometry="6"/>          <speciesReference species="M_tdcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="7"/>          <speciesReference species="M_fadh2_m" stoichiometry="6"/>          <speciesReference species="M_h_m" stoichiometry="6"/>          <speciesReference species="M_nadh_m" stoichiometry="6"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC150m" name="Beta oxidation of long chain fatty acid (odd chain)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="6"/>          <speciesReference species="M_fad_m" stoichiometry="6"/>          <speciesReference species="M_h2o_m" stoichiometry="6"/>          <speciesReference species="M_nad_m" stoichiometry="6"/>          <speciesReference species="M_ptdcacoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="6"/>          <speciesReference species="M_fadh2_m" stoichiometry="6"/>          <speciesReference species="M_h_m" stoichiometry="6"/>          <speciesReference species="M_nadh_m" stoichiometry="6"/>          <speciesReference species="M_ppcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC160" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="7"/>          <speciesReference species="M_fad_m" stoichiometry="7"/>          <speciesReference species="M_h2o_m" stoichiometry="7"/>          <speciesReference species="M_nad_m" stoichiometry="7"/>          <speciesReference species="M_pmtcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="8"/>          <speciesReference species="M_fadh2_m" stoichiometry="7"/>          <speciesReference species="M_h_m" stoichiometry="7"/>          <speciesReference species="M_nadh_m" stoichiometry="7"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC16080m" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="4"/>          <speciesReference species="M_fad_m" stoichiometry="4"/>          <speciesReference species="M_h2o_m" stoichiometry="4"/>          <speciesReference species="M_nad_m" stoichiometry="4"/>          <speciesReference species="M_pmtcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="4"/>          <speciesReference species="M_fadh2_m" stoichiometry="4"/>          <speciesReference species="M_h_m" stoichiometry="4"/>          <speciesReference species="M_nadh_m" stoichiometry="4"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC16080x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51.1 and 3295.1 and 30.1) or (51.1 and 30.1 and 1962.1) or (30.1 and 51.2 and 1962.1) or (3295.1 and 30.1 and 51.2)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="4"/>          <speciesReference species="M_h2o_x" stoichiometry="4"/>          <speciesReference species="M_nad_x" stoichiometry="4"/>          <speciesReference species="M_o2_x" stoichiometry="4"/>          <speciesReference species="M_pmtcoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="4"/>          <speciesReference species="M_h2o2_x" stoichiometry="4"/>          <speciesReference species="M_h_x" stoichiometry="4"/>          <speciesReference species="M_nadh_x" stoichiometry="4"/>          <speciesReference species="M_occoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC161802m" name="Beta oxidation  fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid activation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="4"/>          <speciesReference species="M_fad_m" stoichiometry="3"/>          <speciesReference species="M_h2o_m" stoichiometry="4"/>          <speciesReference species="M_hdd2coa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="4"/>          <speciesReference species="M_fadh2_m" stoichiometry="3"/>          <speciesReference species="M_h_m" stoichiometry="4"/>          <speciesReference species="M_nadh_m" stoichiometry="4"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC16180m" name="Beta oxidation  fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="4"/>          <speciesReference species="M_fad_m" stoichiometry="3"/>          <speciesReference species="M_h2o_m" stoichiometry="4"/>          <speciesReference species="M_hdcoa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="4"/>          <speciesReference species="M_fadh2_m" stoichiometry="3"/>          <speciesReference species="M_h_m" stoichiometry="4"/>          <speciesReference species="M_nadh_m" stoichiometry="4"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC170m" name="Beta oxidation of long chain fatty acid (odd chain)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="7"/>          <speciesReference species="M_fad_m" stoichiometry="7"/>          <speciesReference species="M_h2o_m" stoichiometry="7"/>          <speciesReference species="M_hpdcacoa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="7"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="7"/>          <speciesReference species="M_fadh2_m" stoichiometry="7"/>          <speciesReference species="M_h_m" stoichiometry="7"/>          <speciesReference species="M_nadh_m" stoichiometry="7"/>          <speciesReference species="M_ppcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC180" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (34.1) or (35.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>          <speciesReference species="M_stcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_pmtcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC180x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51.1 and 3295.1 and 30.1) or (51.1 and 30.1 and 1962.1) or (30.1 and 51.2 and 1962.1) or (3295.1 and 30.1 and 51.2)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>          <speciesReference species="M_stcoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>          <speciesReference species="M_pmtcoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC1811601m" name="Beta oxidation  fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="5"/>          <speciesReference species="M_fad_m" stoichiometry="4"/>          <speciesReference species="M_h2o_m" stoichiometry="5"/>          <speciesReference species="M_nad_m" stoichiometry="5"/>          <speciesReference species="M_od2coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="5"/>          <speciesReference species="M_fadh2_m" stoichiometry="4"/>          <speciesReference species="M_h_m" stoichiometry="5"/>          <speciesReference species="M_nadh_m" stoichiometry="5"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC1811602m" name="Beta oxidation  fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="5"/>          <speciesReference species="M_fad_m" stoichiometry="4"/>          <speciesReference species="M_h2o_m" stoichiometry="5"/>          <speciesReference species="M_nad_m" stoichiometry="5"/>          <speciesReference species="M_vacccoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="5"/>          <speciesReference species="M_fadh2_m" stoichiometry="4"/>          <speciesReference species="M_h_m" stoichiometry="5"/>          <speciesReference species="M_nadh_m" stoichiometry="5"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC1811603m" name="Beta oxidation  fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="5"/>          <speciesReference species="M_fad_m" stoichiometry="4"/>          <speciesReference species="M_h2o_m" stoichiometry="5"/>          <speciesReference species="M_nad_m" stoichiometry="5"/>          <speciesReference species="M_odecoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="5"/>          <speciesReference species="M_fadh2_m" stoichiometry="4"/>          <speciesReference species="M_h_m" stoichiometry="5"/>          <speciesReference species="M_nadh_m" stoichiometry="5"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC182806m" name="Beta oxidation of fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="5"/>          <speciesReference species="M_fad_m" stoichiometry="3"/>          <speciesReference species="M_h2o_m" stoichiometry="5"/>          <speciesReference species="M_lnlccoa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="5"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="5"/>          <speciesReference species="M_fadh2_m" stoichiometry="3"/>          <speciesReference species="M_h_m" stoichiometry="5"/>          <speciesReference species="M_nadh_m" stoichiometry="5"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC18280m" name="Beta oxidation of fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="5"/>          <speciesReference species="M_fad_m" stoichiometry="3"/>          <speciesReference species="M_h2o_m" stoichiometry="5"/>          <speciesReference species="M_lneldccoa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="5"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="5"/>          <speciesReference species="M_fadh2_m" stoichiometry="3"/>          <speciesReference species="M_h_m" stoichiometry="5"/>          <speciesReference species="M_nadh_m" stoichiometry="5"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC183803m" name="Beta oxidation of fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="5"/>          <speciesReference species="M_fad_m" stoichiometry="2"/>          <speciesReference species="M_h2o_m" stoichiometry="5"/>          <speciesReference species="M_lnlncacoa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="5"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="5"/>          <speciesReference species="M_fadh2_m" stoichiometry="2"/>          <speciesReference species="M_h_m" stoichiometry="5"/>          <speciesReference species="M_nadh_m" stoichiometry="5"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC183806m" name="Beta oxidation of fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="5"/>          <speciesReference species="M_h2o_m" stoichiometry="5"/>          <speciesReference species="M_lnlncgcoa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="5"/>          <speciesReference species="M_o2_m" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="5"/>          <speciesReference species="M_h2o2_m" stoichiometry="2"/>          <speciesReference species="M_h_m" stoichiometry="5"/>          <speciesReference species="M_nadh_m" stoichiometry="5"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC183806x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (30.1 and 51.2 and 1962.1) or (51.1 and 3295.1 and 30.1) or (51.1 and 30.1 and 1962.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="5"/>          <speciesReference species="M_h2o_x" stoichiometry="5"/>          <speciesReference species="M_lnlncgcoa_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="5"/>          <speciesReference species="M_o2_x" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="5"/>          <speciesReference species="M_h2o2_x" stoichiometry="2"/>          <speciesReference species="M_h_x" stoichiometry="5"/>          <speciesReference species="M_nadh_x" stoichiometry="5"/>          <speciesReference species="M_occoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC18480m" name="Beta oxidation of fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="5"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="5"/>          <speciesReference species="M_nad_m" stoichiometry="5"/>          <speciesReference species="M_strdnccoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="5"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="5"/>          <speciesReference species="M_nadh_m" stoichiometry="5"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC18480x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1) or (3295.1 and 30.1 and 51.2)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="5"/>          <speciesReference species="M_h2o_x" stoichiometry="5"/>          <speciesReference species="M_nad_x" stoichiometry="5"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>          <speciesReference species="M_strdnccoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="5"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="5"/>          <speciesReference species="M_nadh_x" stoichiometry="5"/>          <speciesReference species="M_occoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC200180m" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachcoa_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_stcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC200180x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 30.1 and 1962.1) or (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachcoa_x" stoichiometry="1"/>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>          <speciesReference species="M_stcoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2031836m" name="Beta oxidation of fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_dlnlcgcoa_m" stoichiometry="1"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_lnlncgcoa_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC204" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (35.1) or (34.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachdcoa_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="9"/>          <speciesReference species="M_fad_m" stoichiometry="5"/>          <speciesReference species="M_h2o_m" stoichiometry="9"/>          <speciesReference species="M_nad_m" stoichiometry="9"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="10"/>          <speciesReference species="M_fadh2_m" stoichiometry="5"/>          <speciesReference species="M_h_m" stoichiometry="9"/>          <speciesReference species="M_nadh_m" stoichiometry="9"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC204184m" name="Beta oxidation  fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_eicostetcoa_m" stoichiometry="1"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_strdnccoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2051843m" name="Beta oxidation of fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>          <speciesReference species="M_tmndnccoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_strdnccoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2051843x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (30.1 and 51.2 and 1962.1) or (51.1 and 3295.1 and 30.1) or (51.1 and 30.1 and 1962.1) or (3295.1 and 30.1 and 51.2)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_tmndnccoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>          <speciesReference species="M_strdnccoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2242046m" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adrncoa_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_arachdcoa_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2242046x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 30.1 and 1962.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 3295.1 and 30.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adrncoa_x" stoichiometry="1"/>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_arachdcoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2251836m" name="Beta oxidation of fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (34.1) or (35.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="2"/>          <speciesReference species="M_dcsptn1coa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="2"/>          <speciesReference species="M_nad_m" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="2"/>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_lnlncgcoa_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2251836x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 30.1 and 1962.1) or (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="2"/>          <speciesReference species="M_dcsptn1coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="2"/>          <speciesReference species="M_nad_x" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="2"/>          <speciesReference species="M_h_x" stoichiometry="2"/>          <speciesReference species="M_lnlncgcoa_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2252053m" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_dcsptn1coa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_h2o2_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_tmndnccoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2252053x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1) or (3295.1 and 30.1 and 51.2)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_dcsptn1coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>          <speciesReference species="M_tmndnccoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC226" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_c226coa_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="10"/>          <speciesReference species="M_fad_m" stoichiometry="4"/>          <speciesReference species="M_h2o_m" stoichiometry="10"/>          <speciesReference species="M_nad_m" stoichiometry="10"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="11"/>          <speciesReference species="M_fadh2_m" stoichiometry="4"/>          <speciesReference species="M_h_m" stoichiometry="10"/>          <speciesReference species="M_nadh_m" stoichiometry="10"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC226205m" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_c226coa_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_tmndnccoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC226205x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_c226coa_x" stoichiometry="1"/>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>          <speciesReference species="M_tmndnccoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC240200x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1) or (3295.1 and 30.1 and 51.2)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="2"/>          <speciesReference species="M_h2o_x" stoichiometry="2"/>          <speciesReference species="M_lgnccoa_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="2"/>          <speciesReference species="M_o2_x" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="2"/>          <speciesReference species="M_arachcoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="2"/>          <speciesReference species="M_h_x" stoichiometry="2"/>          <speciesReference species="M_nadh_x" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC241181x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 30.1 and 1962.1) or (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="3"/>          <speciesReference species="M_h2o_x" stoichiometry="3"/>          <speciesReference species="M_nad_x" stoichiometry="3"/>          <speciesReference species="M_nrvnccoa_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="3"/>          <speciesReference species="M_h2o2_x" stoichiometry="3"/>          <speciesReference species="M_h_x" stoichiometry="3"/>          <speciesReference species="M_nadh_x" stoichiometry="3"/>          <speciesReference species="M_odecoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2442246x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51.1 and 3295.1 and 30.1) or (51.1 and 30.1 and 1962.1) or (30.1 and 51.2 and 1962.1) or (3295.1 and 30.1 and 51.2)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>          <speciesReference species="M_tettet6coa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_adrncoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2452253x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1) or (51.1 and 3295.1 and 30.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>          <speciesReference species="M_tetpent3coa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_clpndcoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC2452256x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>          <speciesReference species="M_tetpent6coa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_dcsptn1coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC246226x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>          <speciesReference species="M_tethex3coa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_c226coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC260240x" name="Beta oxidation of long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 30.1 and 1962.1) or (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation, peroxisome</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_hexccoa_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_lgnccoa_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAOXC80" name="Beta oxidation of med/long chain fatty acid" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (35.1) or (34.1)</p>            <p>SUBSYSTEM: Fatty acid oxidation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="3"/>          <speciesReference species="M_fad_m" stoichiometry="3"/>          <speciesReference species="M_h2o_m" stoichiometry="3"/>          <speciesReference species="M_nad_m" stoichiometry="3"/>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="4"/>          <speciesReference species="M_fadh2_m" stoichiometry="3"/>          <speciesReference species="M_h_m" stoichiometry="3"/>          <speciesReference species="M_nadh_m" stoichiometry="3"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAS100COA" name="fatty acyl-CoA synthase (n-C10:0CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2194.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="3"/>          <speciesReference species="M_malcoa_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="2"/>          <speciesReference species="M_occoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_dcacoa_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAS120COA" name="fatty-acyl-CoA synthase (n-C12:0CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2194.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcacoa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="3"/>          <speciesReference species="M_malcoa_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_ddcacoa_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAS140COA" name="fatty-acyl-CoA synthase (n-C14:0CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2194.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ddcacoa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="3"/>          <speciesReference species="M_malcoa_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="2"/>          <speciesReference species="M_tdcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAS160COA" name="fatty-acyl-CoA synthase (n-C16:0CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2194.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="3"/>          <speciesReference species="M_malcoa_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="2"/>          <speciesReference species="M_tdcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="2"/>          <speciesReference species="M_pmtcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAS180COA" name="fatty-acyl-CoA synthase (n-C18:0CoA)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2194.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="3"/>          <speciesReference species="M_malcoa_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="2"/>          <speciesReference species="M_pmtcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="2"/>          <speciesReference species="M_stcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FAS80COA_L" name="fatty acyl-CoA synthase (n-C8:0CoA), lumped reaction" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2194.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="9"/>          <speciesReference species="M_malcoa_c" stoichiometry="3"/>          <speciesReference species="M_nadph_c" stoichiometry="6"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="3"/>          <speciesReference species="M_coa_c" stoichiometry="3"/>          <speciesReference species="M_h2o_c" stoichiometry="3"/>          <speciesReference species="M_nadp_c" stoichiometry="6"/>          <speciesReference species="M_occoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FATP1t" name="fatty acid electroneutral transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (376497.2) or (10999.1) or (376497.1) or (11000.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hdca_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hdca_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FATP2t" name="fatty acid electroneutral transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (376497.1) or (376497.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_ocdcea_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_ocdcea_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FATP3t" name="fatty acid electroneutral transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (376497.1) or (376497.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_ocdca_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_ocdca_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FATP4t" name="fatty acid electroneutral transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10998.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arach_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arach_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FATP5t" name="fatty acid electroneutral transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10998.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arachd_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_arachd_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FATP6t" name="fatty acid electroneutral transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10998.1) or (11001.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adrn_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adrn_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FATP7t" name="fatty acid electroneutral transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10998.1) or (11001.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crvnc_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crvnc_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FATP8t" name="fatty acid electroneutral transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10998.1) or (11001.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lgnc_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lgnc_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FATP9t" name="fatty acid electroneutral transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10998.1) or (11001.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_nrvnc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_nrvnc_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FBA" name="fructose-bisphosphate aldolase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (226.2) or (226.1) or (226.3) or (230.1) or (229.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fdp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhap_c" stoichiometry="1"/>          <speciesReference species="M_g3p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FBA2" name="D-Fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (226.2) or (226.1) or (226.3) or (229.1) or (230.1)</p>            <p>SUBSYSTEM: Fructose and Mannose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_f1p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhap_c" stoichiometry="1"/>          <speciesReference species="M_glyald_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FBA4" name="D-Fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (226.2) or (229.1) or (226.3) or (230.1) or (226.1)</p>            <p>SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xu1p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhap_c" stoichiometry="1"/>          <speciesReference species="M_gcald_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FBA5" name="D-Tagatose 1-phosphate D-glyceraldehyde-3-phosphate-lyase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (229.1)</p>            <p>SUBSYSTEM: Galactose metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tag1p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhap_c" stoichiometry="1"/>          <speciesReference species="M_glyald_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FBP" name="fructose-bisphosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2203.1) or (8789.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fdp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_f6p_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FBP26" name="Fructose-2,6-bisphosphate 2-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2203.1) or (5210.1) or (5207.1) or (5209.1) or (5208.1) or (8789.1)</p>            <p>SUBSYSTEM: Fructose and Mannose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_f26bp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_f6p_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FCLTm" name="Ferrochelatase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2235.1) or (2235.2)</p>            <p>SUBSYSTEM: Heme Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fe2_m" stoichiometry="1"/>          <speciesReference species="M_ppp9_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_pheme_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FDH" name="formate dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10840.1)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_for_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FE2tm" name="iron (II) transport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fe2_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fe2_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FE3R2e" name="Fe(III) reduction (ascorbate)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (79901.1)</p>            <p>SUBSYSTEM: Heme Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ascb_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_fe3_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhdascb_e" stoichiometry="1"/>          <speciesReference species="M_fe2_e" stoichiometry="2"/>          <speciesReference species="M_h_e" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FKYNH" name="N-Formyl-L-kynurenine amidohydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Lfmkynr_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Lkynr_c" stoichiometry="1"/>          <speciesReference species="M_for_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FMNAT" name="FMN adenylyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (80308.1) or (80308.2)</p>            <p>SUBSYSTEM: Riboflavin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_fmn_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fad_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FOLR2" name="folate reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1719.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fol_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhf_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FOLt2" name="folate transport via anion exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6573.1) or (6573.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fol_e" stoichiometry="1"/>          <speciesReference species="M_oh1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fol_c" stoichiometry="1"/>          <speciesReference species="M_oh1_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FORtr" name="FOR transporter, endoplasmic reticulum" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_for_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_for_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FPGS" name="folylpolyglutamate synthetase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2356.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="4"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="4"/>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5thf_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="4"/>          <speciesReference species="M_h_c" stoichiometry="4"/>          <speciesReference species="M_pi_c" stoichiometry="4"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FPGS2" name="folylpolyglutamate synthetase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2356.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5thf_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6thf_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FPGS3" name="folylpolyglutamate synthetase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2356.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_6thf_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_7thf_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FPGS4" name="folylpolyglutamate synthetase (DHF)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2356.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="4"/>          <speciesReference species="M_dhf_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5dhf_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="4"/>          <speciesReference species="M_h_c" stoichiometry="4"/>          <speciesReference species="M_pi_c" stoichiometry="4"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FPGS5" name="folylpolyglutamate  synthetase (DHF)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2356.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5dhf_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6dhf_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FPGS6" name="folylpolyglutamate synthetase (DHF)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2356.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_6dhf_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_7dhf_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FPGS7" name="folylpolyglutamate synthetase (10fthf)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2356.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="4"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf5glu_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="4"/>          <speciesReference species="M_h_c" stoichiometry="4"/>          <speciesReference species="M_pi_c" stoichiometry="4"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FPGS8" name="folylpolyglutamate synthetase (10fthf)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2356.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf5glu_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf6glu_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FPGS9" name="folylpolyglutamate synthetase (10fthf)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2356.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf6glu_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf7glu_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FRDPtr" name="lipid, flip-flop intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_frdp_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_frdp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FRUt1r" name="D-fructose transport in via uniport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (29988.1) or (6514.1) or (155184.1) or (6518.1) or (66035.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fru_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fru_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FRUt4" name="D-fructose transport  via sodium cotransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (200010.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fru_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fru_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FTCD" name="formimidoyltransferase cyclodeaminase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10841.1) or (10841.2)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5forthf_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_methf_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FTHFCL" name=" 5-formethyltetrahydrofolate cyclo-ligase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10588.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5fthf_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_methf_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FTHFDH" name="formyltetrahydrofolate dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10840.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FTHFL" name="formate-tetrahydrofolate ligase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4522.1) or (286297.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_for_c" stoichiometry="1"/>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FUCASEe" name="alpha-fucosidase, extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2519.1)</p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_e" stoichiometry="1"/>          <speciesReference species="M_s2l2fn2m2masn_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fuc_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_s2l2n2m2masn_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FUM" name="fumarase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2271.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fum_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mal_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FUMAC" name="fumarylacetoacetase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2184.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4fumacac_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acac_c" stoichiometry="1"/>          <speciesReference species="M_fum_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_FUMm" name="fumarase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2271.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fum_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mal_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G3PD1" name="glycerol-3-phosphate dehydrogenase (NAD)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2819.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glyc3p_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhap_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G3PD2m" name="glycerol-3-phosphate dehydrogenase (FAD), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2820.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_glyc3p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhap_c" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G5SADrm" name="L-glutamate 5-semialdehyde dehydratase, reversible, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glu5sa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_1pyr5c_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G5SDym" name="glutamate-5-semialdehyde dehydrogenase (m)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5832.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glu5p_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu5sa_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G6PDA" name="glucosamine-6-phosphate deaminase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (132789.1) or (10007.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gam6p_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_f6p_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G6PDH1er" name="glucose-6-phosphate dehydrogenase, endoplasmic reticulum" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9563.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g6p_r" stoichiometry="1"/>          <speciesReference species="M_nad_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6pgl_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadh_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G6PDH1rer" name="glucose-6-phosphate dehydrogenase, endoplasmic reticulum" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9563.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g6p_r" stoichiometry="1"/>          <speciesReference species="M_nad_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6pgl_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadh_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G6PDH2r" name="glucose 6-phosphate dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2539.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g6p_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6pgl_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G6PDH2rer" name="glucose 6-phosphate dehydrogenase, endoplasmic reticulum" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9563.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g6p_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6pgl_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G6PPer" name="glucose-6-phosphate phosphatase, edoplasmic reticular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (57818.1) or (2538.1) or (92579.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g6p_r" stoichiometry="1"/>          <speciesReference species="M_h2o_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glc_DASH_DASH_DASH_D_r" stoichiometry="1"/>          <speciesReference species="M_pi_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_G6Pter" name="glucose 6-phosphate endoplasmic reticular transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2542.1)</p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g6p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_g6p_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GACMTRc" name="guanidinoacetate N-methyltransferase (c)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2593.1) or (2593.2)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amet_c" stoichiometry="1"/>          <speciesReference species="M_gudac_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ahcys_c" stoichiometry="1"/>          <speciesReference species="M_creat_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GALASE1ly" name="beta-galactosidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1) or (5476.1) and (2720.1)</p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="2"/>          <speciesReference species="M_l2n2m2mn_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gal_l" stoichiometry="2"/>          <speciesReference species="M_n2m2mn_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GALK" name="galactokinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2584.1) or (2585.2) or (2585.1)</p>            <p>SUBSYSTEM: Galactose metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_gal_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_gal1p_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GALT" name="galactose-1-phosphate uridylyltransferase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2592.1) or (2592.3) or (2592.2)</p>            <p>SUBSYSTEM: Galactose metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gal1p_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_utp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_udpgal_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GALU" name="UTP-glucose-1-phosphate uridylyltransferase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7360.1) or (7359.1) or (7360.2)</p>            <p>SUBSYSTEM: Galactose metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g1p_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_utp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_udpg_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GALt1r" name="galactose transport (uniport)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (29988.1) or (6513.1) or (6515.1) or (6514.1) or (81031.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gal_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gal_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GALt4" name="galactose transport via sodium symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (200010.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gal_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gal_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GALtly" name="galactose efflux from lysosome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gal_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gal_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GAMt1r" name="glucosamine transport (uniport)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6513.1) or (6517.1) or (6514.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gam_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gam_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GAPD" name="glyceraldehyde-3-phosphate dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2597.1) or (26330.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g3p_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_13dpg_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GARFT" name="phosphoribosylglycinamide formyltransferase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2618.1) or (2618.2)</p>            <p>SUBSYSTEM: IMP Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf_c" stoichiometry="1"/>          <speciesReference species="M_gar_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fgam_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GASNASE2ly" name="glycosylasparaginase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (175.1)</p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="1"/>          <speciesReference species="M_n2m2nmasn_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Asn_DASH_DASH_DASH_X_DASH_DASH_DASH_Ser_DASH_FSLASH_DASH_Thr_l" stoichiometry="1"/>          <speciesReference species="M_n2m2nm_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GASNASEly" name="glycosylasparaginase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (175.1)</p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="1"/>          <speciesReference species="M_s2l2n2m2masn_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Asn_DASH_DASH_DASH_X_DASH_DASH_DASH_Ser_DASH_FSLASH_DASH_Thr_l" stoichiometry="1"/>          <speciesReference species="M_s2l2n2m2m_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GBA" name="Glucosylceramidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2629.2) or (2629.3) or (2629.4) or (2629.5) or (2629.1)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gluside_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crm_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_glc_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCALDD" name="Glycolaldehyde dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (218.1) or (223.1) or (8854.2) or (224.1) or (222.1) or (8854.1) or (221.1) or (216.1) or (8854.3) or (501.1) or (220.1)</p>            <p>SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gcald_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glyclt_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCC2am" name="glycine-cleavage complex (lipoamide), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (275.1) and (1738.1) and (2731.1) and (2653.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gly_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_lpam_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_alpam_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCC2bim" name="glycine-cleavage system (lipoamide) irreversible, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (275.1) and (1738.1) and (2731.1) and (2653.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_alpam_m" stoichiometry="1"/>          <speciesReference species="M_thf_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhlam_m" stoichiometry="1"/>          <speciesReference species="M_mlthf_m" stoichiometry="1"/>          <speciesReference species="M_nh4_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCC2cm" name="glycine-cleavage complex (lipoamide), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (275.1) and (1738.1) and (2731.1) and (2653.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhlam_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_lpam_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCCam" name="glycine-cleavage complex (lipoylprotein), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (275.1) and (1738.1) and (2731.1) and (2653.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gly_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_lpro_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_alpro_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCCbim" name="glycine-cleavage complex (lipoylprotein) irreversible, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (275.1) and (1738.1) and (2731.1) and (2653.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_alpro_m" stoichiometry="1"/>          <speciesReference species="M_thf_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhlpro_m" stoichiometry="1"/>          <speciesReference species="M_mlthf_m" stoichiometry="1"/>          <speciesReference species="M_nh4_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCCcm" name="glycine-cleavage complex (lipoylprotein), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (275.1) and (1738.1) and (2731.1) and (2653.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhlpro_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_lpro_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCHOLAt" name="glycocholate transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6579.1) or (28234.1) or (10599.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gchola_e" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gchola_c" stoichiometry="1"/>          <speciesReference species="M_hco3_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCHOLAt2" name="glycocholate transport via sodium cotransport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6554.1) or (6555.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gchola_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gchola_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCHOLAt3" name="ABC bile acid transporter" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8714.3) or (8647.1) or (8714.2) or (8714.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_gchola_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_gchola_e" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GCHOLAtx" name="bile acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gchola_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gchola_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GDCHOLAte" name="bile acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gdchola_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gdchola_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GDCHOLAtx" name="bile acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gdchola_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gdchola_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GF6PTA" name="glutamine-fructose-6-phosphate transaminase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2673.1) or (9945.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_f6p_c" stoichiometry="1"/>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gam6p_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_10FTHF5GLUe" name="Gamma-glutamyl hydrolase (10FTHF5GLU), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf5glu_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf_e" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_e" stoichiometry="4"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_10FTHF5GLUl" name="Gamma-glutamyl hydrolase (10FTHF5GLU), lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf5glu_l" stoichiometry="1"/>          <speciesReference species="M_h2o_l" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf_l" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_l" stoichiometry="4"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_10FTHF6GLUe" name="Gamma-glutamyl hydrolase (10FTHF6GLU), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf6glu_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf5glu_e" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_10FTHF6GLUl" name="Gamma-glutamyl hydrolase (10FTHF6GLU), lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf6glu_l" stoichiometry="1"/>          <speciesReference species="M_h2o_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf5glu_l" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_10FTHF7GLUe" name="Gamma-glutamyl hydrolase (10FTHF7GLU), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf7glu_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf6glu_e" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_10FTHF7GLUl" name="Gamma-glutamyl hydrolase (10FTHF7GLU), lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_10fthf7glu_l" stoichiometry="1"/>          <speciesReference species="M_h2o_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf6glu_l" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_5DHFe" name="Gamma-glutamyl hydrolase (5DHF), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5dhf_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhf_e" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_e" stoichiometry="4"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_5DHFl" name="Gamma-glutamyl hydrolase (5DHF), lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5dhf_l" stoichiometry="1"/>          <speciesReference species="M_h2o_l" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhf_l" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_l" stoichiometry="4"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_5THFe" name="Gamma-glutamyl hydrolase (5THF), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5thf_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_e" stoichiometry="4"/>          <speciesReference species="M_thf_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_5THFl" name="Gamma-glutamyl hydrolase (5THF), lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5thf_l" stoichiometry="1"/>          <speciesReference species="M_h2o_l" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_l" stoichiometry="4"/>          <speciesReference species="M_thf_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_6DHFe" name="Gamma-glutamyl hydrolase (6DHF), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_6dhf_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5dhf_e" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_6DHFl" name="Gamma-glutamyl hydrolase (6DHF), lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_6dhf_l" stoichiometry="1"/>          <speciesReference species="M_h2o_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5dhf_l" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_6THFe" name="Gamma-glutamyl hydrolase (6THF), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_6thf_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5thf_e" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_6THFl" name="Gamma-glutamyl hydrolase (6THF), lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_6thf_l" stoichiometry="1"/>          <speciesReference species="M_h2o_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5thf_l" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_7DHFe" name="Gamma-glutamyl hydrolase (7DHF), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7dhf_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6dhf_e" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_7DHFl" name="Gamma-glutamyl hydrolase (7DHF), lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7dhf_l" stoichiometry="1"/>          <speciesReference species="M_h2o_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6dhf_l" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_7THFe" name="Gamma-glutamyl hydrolase (7THF), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7thf_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6thf_e" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGH_7THFl" name="Gamma-glutamyl hydrolase (7THF), lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8836.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7thf_l" stoichiometry="1"/>          <speciesReference species="M_h2o_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6thf_l" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGLUCT" name="gamma-glutamylcyclotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2655.1)</p>            <p>SUBSYSTEM: Glutathione Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gluala_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5oxpro_c" stoichiometry="1"/>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGNG" name="glycogenin self-glucosylation" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8908.1) and (2998.1) or (2998.1) and (2992.1) or (2997.1) and (2992.1) or (8908.1) and (2997.1)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Tyr_DASH_DASH_DASH_ggn_c" stoichiometry="1"/>          <speciesReference species="M_udpg_c" stoichiometry="8"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ggn_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="8"/>          <speciesReference species="M_udp_c" stoichiometry="8"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGT5r" name="Gamma-glutamyltransferase 5" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2687.1)</p>            <p>SUBSYSTEM: Eicosanoid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_leuktrC4_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_r" stoichiometry="1"/>          <speciesReference species="M_leuktrD4_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GGT6" name="Gamma-glutamyltransferase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Eicosanoid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_leuktrE4_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_leuktrF4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GHMT2r" name="glycine hydroxymethyltransferase, reversible" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6470.1) or (6470.2)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gly_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mlthf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GK1" name="guanylate kinase (GMP:ATP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2987.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_gmp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_gdp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLBRAN" name=" 1,4-alpha-glucan branching enzyme (glygn1 -&gt; glygn2)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2632.1)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glygn1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glygn2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLCAASE8ly" name="beta-glucuronidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2990.1)</p>            <p>SUBSYSTEM: Hyaluronan Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="1"/>          <speciesReference species="M_ha_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glcur_l" stoichiometry="1"/>          <speciesReference species="M_ha_DASH_deg1_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLCAASE9ly" name="beta-glucuronidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2990.1)</p>            <p>SUBSYSTEM: Hyaluronan Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="2"/>          <speciesReference species="M_ha_DASH_pre1_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam_l" stoichiometry="1"/>          <speciesReference species="M_glcur_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLCURter" name="glucuronate endoplasmic reticular transport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glcur_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glcur_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLCURtly" name="glucuronate transport into lysososme" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (26503.1)</p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glcur_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glcur_l" stoichiometry="1"/>          <speciesReference species="M_h_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLCt1r" name="glucose transport (uniport)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (66035.1) or (6517.1) or (56606.1) or (154091.1) or (6513.1) or (11182.1) or (29988.1) or (6514.1) or (155184.1) or (56606.2) or (144195.1) or (6515.1) or (81031.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glc_DASH_DASH_DASH_D_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glc_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLCt4" name="glucose transport via sodium symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (200010.1) or (159963.1) or (6526.1) or (125206.1) or (6524.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glc_DASH_DASH_DASH_D_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glc_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLCter" name="glucose transport, endoplasmic reticulum" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glc_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glc_DASH_DASH_DASH_D_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLDBRAN" name="glycogen debranching enzyme" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (178.4) or (178.5) or (178.1) or (178.3) or (178.2) or (178.6)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dxtrn_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glc_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_glygn3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLGNS1" name="glycogen synthase (ggn -&gt; glygn1)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8908.1) and (2997.1) or (2998.1) and (2992.1) or (2997.1) and (2992.1) or (8908.1) and (2998.1)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ggn_c" stoichiometry="1"/>          <speciesReference species="M_udpg_c" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glygn1_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="3"/>          <speciesReference species="M_udp_c" stoichiometry="3"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLNS" name="glutamine synthetase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2752.1) or (51557.1)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLNt4" name="L-glutamine reversible transport via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (81539.1) or (11254.1) or (54407.1) or (55089.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gln_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLNtN1" name="Glutamine transport (Na, H coupled)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (92745.1) or (10991.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gln_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLNtm" name="L-glutamine transport via electroneutral transporter" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gln_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLPASE1" name="glycogen phosphorylase (glygn2 -&gt; dxtrn)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5834.1) or (5837.1) or (5836.1)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glygn2_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dxtrn_c" stoichiometry="1"/>          <speciesReference species="M_g1p_c" stoichiometry="3"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLPASE2" name="glycogen phosphorylase (amyls -&gt; glc-D)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5834.1) or (5836.1) or (5837.1)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glygn3_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="7"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Tyr_DASH_DASH_DASH_ggn_c" stoichiometry="1"/>          <speciesReference species="M_glc_DASH_DASH_DASH_D_c" stoichiometry="7"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLU5Km" name="glutamate 5-kinase (m)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5832.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_glu5p_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLUCYS" name="gamma-glutamylcysteine synthetase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2729.1) and (2730.1)</p>            <p>SUBSYSTEM: Glutathione Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_glucys_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLUDxm" name="glutamate dehydrogenase (NAD) (mitochondrial)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2747.1) or (2746.1)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_nh4_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLUDym" name="glutamate dehydrogenase (NADP), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2747.1) or (2746.1)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>          <speciesReference species="M_nh4_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLUNm" name="glutaminase (mitochondrial)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2744.1) or (27165.2) or (27165.1)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gln_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_nh4_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLUPRT" name="glutamine phosphoribosyldiphosphate amidotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5471.1)</p>            <p>SUBSYSTEM: IMP Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_prpp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_pram_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLUTCOADHm" name="glutaryl-CoA dehydrogenase (mitochondria)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2639.1) or (2639.2)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_glutcoa_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_b2coa_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLUt2m" name="L-glutamate reversible transport via proton symport, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (83733.1) or (8604.1) or (79751.1) or (10165.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLUt6" name="Glutamate transport via Na, H symport and K antiport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6511.1) or (6505.1) or (6507.1) or (6506.1) or (6512.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glu_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_k_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_k_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="3"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLUt7l" name="Glutamate transport, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glu_DASH_DASH_DASH_L_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLUtr" name="intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLXO1" name="glyoxylate oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3939.1) or (55293.1) or (3945.1 and 3939.1) or (197257.1) or (92483.1) or (3945.1) or (160287.1) or (3948.1) or (197257.2) or (3948.2)</p>            <p>SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glx_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_oxa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLXO2p" name="glyoxylate oxidase, peroxisomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54363.1) or (51179.2) or (51179.1)</p>            <p>SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glx_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_oxa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLXtp" name="glyoxylate transport, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glx_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glx_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYAMDTRc" name="glycine amidinotransferase (c)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2628.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arg_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_gly_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gudac_c" stoichiometry="1"/>          <speciesReference species="M_orn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYATm" name="glycine C-acetyltransferase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23464.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_gly_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2aobut_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYBt4_LPAREN_2_RPAREN_r" name="Betaine transport (sodium symport) (2:1)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6539.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glyb_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glyb_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYBtm" name="Glycine betaine transport via diffusion (mitochondria to cytosol)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glyb_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glyb_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYCK2" name="glycerate kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glyc_DASH_DASH_DASH_R_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2pg_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYCLTDy" name="Glycolate dehydrogenase (NADP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9380.1)</p>            <p>SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glx_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glyclt_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYCLTtp" name="glycolate transport into peroxisome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glyclt_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glyclt_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYCTO1p" name="Glycolate oxidase, peroxisome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51179.1) or (54363.1) or (51179.2)</p>            <p>SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glyclt_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glx_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYC_St" name="L-glycerate export" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glyc_DASH_DASH_DASH_S_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glyc_DASH_DASH_DASH_S_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYCt" name="glycerol transport via channel" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glyc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glyc_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYK" name="glycerol kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2710.2) or (2712.1) or (2710.1) or (2713.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glyc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_glyc3p_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYOX" name="hydroxyacylglutathione hydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3029.1) or (84264.2) or (84264.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_lgt_DASH_DASH_DASH_S_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gthrd_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lac_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GLYt4" name="glycine transport via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (81539.1) or (11254.1) or (54407.1) or (55089.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gly_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gly_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GMPR" name="GMP reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2766.1) or (51292.1) or (51292.3) or (51292.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gmp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_imp_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GMPS2" name="GMP synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8833.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_xmp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_gmp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GND" name="phosphogluconate dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5226.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_6pgc_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_ru5p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GNMT" name="glycine N-methyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (27232.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amet_c" stoichiometry="1"/>          <speciesReference species="M_gly_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ahcys_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_sarcs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GPAM_hs" name="glycerol-3-phosphate acyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (57678.1)</p>            <p>SUBSYSTEM: Triacylglycerol Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotalcoa_c" stoichiometry="1"/>          <speciesReference species="M_glyc3p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_alpa_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GPDDA1" name="Glycerophosphodiester phosphodiesterase (Glycerophosphocholine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g3pc_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chol_c" stoichiometry="1"/>          <speciesReference species="M_glyc3p_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GRTTx" name="geranyltranstransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2224.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_grdp_x" stoichiometry="1"/>          <speciesReference species="M_ipdp_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_frdp_x" stoichiometry="1"/>          <speciesReference species="M_ppi_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GSNt" name="guanosine facilated transport in cytosol" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3177.1) or (2030.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gsn_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gsn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GTHO" name="glutathione oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2936.1)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthox_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gthrd_c" stoichiometry="2"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GTHOm" name="glutathione oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2936.1)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthox_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gthrd_m" stoichiometry="2"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GTHP" name="glutathione peridoxase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7001.3) or (5052.3) or (2877.1) or (2876.2) or (5052.2) or (2876.1) or (5052.1) or (7001.1) or (2879.1) or (7001.2)</p>            <p>SUBSYSTEM: Glutathione Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthrd_c" stoichiometry="2"/>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gthox_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GTHPe" name="glutathione peroxidase (e)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2878.1) or (257202.1)</p>            <p>SUBSYSTEM: Glutathione Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthrd_e" stoichiometry="2"/>          <speciesReference species="M_h2o2_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gthox_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GTHPm" name="glutathione peroxidase, mitochondria" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10935.1) or (10935.2) or (2879.1)</p>            <p>SUBSYSTEM: Glutathione Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthrd_m" stoichiometry="2"/>          <speciesReference species="M_h2o2_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gthox_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GTHRDtr" name="glutathione transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthrd_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gthrd_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GTHS" name="glutathione synthetase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2937.1)</p>            <p>SUBSYSTEM: Glutathione Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glucys_c" stoichiometry="1"/>          <speciesReference species="M_gly_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_gthrd_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GTMLTe" name="g-glutamyltransferase (e)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2679.1) or (2678.1) or (2678.3) or (2678.2)</p>            <p>SUBSYSTEM: Glutathione Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_gthrd_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cgly_e" stoichiometry="1"/>          <speciesReference species="M_gluala_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GUACYC" name="guanylate cyclase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2977.1 and 2983.1) or (4882.2) or (2982.1 and 2974.1) or (2986.1) or (4882.1) or (2984.1) or (4881.1) or (2977.1 and 2974.1) or (3000.1) or (2982.1 and 2983.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gtp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_35cgmp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GUAD" name="guanine deaminase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9615.1)</p>            <p>SUBSYSTEM: Purine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gua_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nh4_c" stoichiometry="1"/>          <speciesReference species="M_xan_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GUAPRT" name="guanine phosphoribosyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3251.1)</p>            <p>SUBSYSTEM: Salvage Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gua_c" stoichiometry="1"/>          <speciesReference species="M_prpp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gmp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GULN3D" name="L-gulonate 3-dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Pentose and Glucuronate Interconversions</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_guln_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3dhguln_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GULNDer" name="gulonate dehydrogenase, endoplasmic reticulum" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Pentose and Glucuronate Interconversions</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glcur_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_guln_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GULNter" name="L-gulonate endoplasmic reticular export" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_guln_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_guln_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_GluForTx" name="Glutamate formimidoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10841.1) or (10841.2)</p>            <p>SUBSYSTEM: Histidine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_forglu_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5forthf_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_H2CO3D" name="carboxylic acid dissociation" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (761.1) or (771.1) or (377677.1) or (762.1) or (766.2) or (23632.1) or (766.1) or (771.2) or (759.1) or (768.1) or (760.1)</p>            <p>SUBSYSTEM: Miscellaneous</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2co3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_H2CO3D2" name="carboxylic acid dissociation" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Miscellaneous</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_hco3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2co3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_H2CO3D2m" name="carboxylic acid dissociation, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Miscellaneous</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_hco3_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2co3_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_H2CO3Dm" name="carboxylic acid dissociation" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (763.1) or (11238.1)</p>            <p>SUBSYSTEM: Miscellaneous</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2co3_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_H2O2syn" name="Hydrogen peroxide synthesis (NADPH dependent)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (53905.1) or (50506.1) or (53905.2)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_H2O2t" name="hydrogen peroxide transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o2_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_H2O2tn" name="hydrogen peroxide nuclear transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_H2Otly" name="H2O transport, lysosomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_H2Otn" name="H2O transport, nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HACD1m" name=" 3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) (mitochondria)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3028.1) or (3033.1) or (3030.1) and (3032.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_aacoa_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3hbcoa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HACD9m" name=" 3-hydroxyacyl-CoA dehydrogenase (2-Methylacetoacetyl-CoA), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3028.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3hmbcoa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2maacoa_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HAS1" name="hyaluronan synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3038.2) or (3036.1) or (3038.1) or (3037.1)</p>            <p>SUBSYSTEM: Hyaluronan Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_uacgam_c" stoichiometry="1"/>          <speciesReference species="M_udpglcur_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_ha_DASH_pre1_e" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HAS2" name="hyaluronan synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3038.2) or (3036.1) or (3038.1) or (3037.1)</p>            <p>SUBSYSTEM: Hyaluronan Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ha_DASH_pre1_e" stoichiometry="1"/>          <speciesReference species="M_uacgam_c" stoichiometry="1"/>          <speciesReference species="M_udpglcur_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_ha_e" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HAtly" name="hyaluronan transport, extracellular to lysosome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ha_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ha_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HCO3_NAt" name="bicarbonate transport (Na/HCO3 cotransport)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9497.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hco3_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hco3_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HCOUMARINte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hcoumarin_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hcoumarin_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HDCAter" name="palmitate ER export" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hdca_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hdca_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HDCAtr" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hdca_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hdca_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HDCEAtr" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hdcea_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hdcea_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HDD2COAtx" name="hdd2coa intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hdd2coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hdd2coa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HESTRATRIOLte" name="hydroxylated estrogen derivative transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hestratriol_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hestratriol_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HESTRATRIOLtr" name="hydroxylated estrogen derivative transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hestratriol_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hestratriol_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HEX10" name="hexokinase (D-glucosamine:ATP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2645.1) or (3099.1) or (3098.3) or (2645.2) or (80201.1) or (3098.2) or (2645.3) or (3098.1) or (3098.4) or (3101.1) or (3098.5)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_gam_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_gam6p_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HEX4" name="hexokinase (D-mannose:ATP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3098.2) or (2645.2) or (3101.1) or (2645.3) or (3098.4) or (3098.3) or (3098.5) or (3099.1) or (3098.1) or (80201.1) or (2645.1)</p>            <p>SUBSYSTEM: Fructose and Mannose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_man_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_man6p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HEXCCOAtx" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hexccoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hexccoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HEXCt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hexc_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hexc_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HGNTOR" name="Homogentisate:oxygen 1,2-oxidoreductase (decyclizing)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3081.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hgentis_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4mlacac_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HIBDm" name=" 3-hydroxyisobutyrate dehydrogenase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11112.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3hmp_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2mop_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HISD" name="histidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3034.1)</p>            <p>SUBSYSTEM: Histidine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_his_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nh4_c" stoichiometry="1"/>          <speciesReference species="M_urcan_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HISDC" name="histidine decarboxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1644.1) or (3067.1)</p>            <p>SUBSYSTEM: Histidine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_his_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_hista_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HISTAVESSEC" name="Histamine secretion via secretory vesicle (ATP driven)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6570.1) or (6571.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="2"/>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_hista_c" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="2"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_hista_e" stoichiometry="3"/>          <speciesReference species="M_pi_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HISTAtu" name="Histamine uniport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6581.1) or (6582.2) or (6582.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hista_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hista_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HISt4" name="L-histidine transport in via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11254.1) or (54407.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_his_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_his_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HIStN1" name="Histidine transport (Na, H coupled)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10991.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_his_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_his_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HIStiDF" name="L-histidine transport via diffusion (extracellular to cytosol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55089.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_his_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_his_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HKYNH" name=" 3-Hydroxy-L-kynurenine hydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8942.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_hLkynr_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3hanthrn_c" stoichiometry="1"/>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HMBS" name="hydroxymethylbilane synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3145.1)</p>            <p>SUBSYSTEM: Heme Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_ppbng_c" stoichiometry="4"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hmbil_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="4"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HMGCOARx" name="Hydroxymethylglutaryl CoA reductase (ir)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3156.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_x" stoichiometry="2"/>          <speciesReference species="M_hmgcoa_x" stoichiometry="1"/>          <speciesReference species="M_nadph_x" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_mev_DASH_DASH_DASH_R_x" stoichiometry="1"/>          <speciesReference species="M_nadp_x" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HMGCOASi" name="Hydroxymethylglutaryl CoA synthase (ir)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3157.1) or (3157.2)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_aacoa_c" stoichiometry="1"/>          <speciesReference species="M_accoa_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_hmgcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HMGCOASim" name="Hydroxymethylglutaryl CoA synthase (ir)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3158.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_aacoa_m" stoichiometry="1"/>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_hmgcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HMGCOAtx" name="Hydroxymethylglutaryl-CoA reversible peroxisomal transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hmgcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hmgcoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HMGLm" name="hydroxymethylglutaryl-CoA lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3155.1) or (54511.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hmgcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acac_m" stoichiometry="1"/>          <speciesReference species="M_accoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HMGLx" name="hydroxymethylglutaryl-CoA lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3155.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hmgcoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acac_x" stoichiometry="1"/>          <speciesReference species="M_accoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HOXG" name="Heme oxygenase 1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3162.1) or (3163.1)</p>            <p>SUBSYSTEM: Heme Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="5"/>          <speciesReference species="M_nadph_c" stoichiometry="3"/>          <speciesReference species="M_o2_c" stoichiometry="3"/>          <speciesReference species="M_pheme_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_biliverd_c" stoichiometry="1"/>          <speciesReference species="M_co_c" stoichiometry="1"/>          <speciesReference species="M_fe2_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="3"/>          <speciesReference species="M_nadp_c" stoichiometry="3"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HPACtr" name="hydroxyphenylacetate transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4hphac_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4hphac_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HPDCACRNCPT1" name="carnitine fatty-acyl transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.2) or (1375.3) or (1374.1) or (126129.1) or (1375.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_hpdcacoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_hpdcacrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HPDCACRNCPT2" name="heptadecanoate transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_hpdcacrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_hpdcacoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HPDCACRNt" name="heptadecanoate transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hpdcacrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hpdcacrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HPDCAt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hpdca_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hpdca_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HPYRR2x" name="hydroxypyruvate reductase (NADH)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3948.1) or (197257.1) or (3945.1) or (160287.1) or (3945.1 and 3939.1) or (92483.1) or (3939.1) or (197257.2) or (3948.2)</p>            <p>SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_hpyr_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glyc_DASH_DASH_DASH_S_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HPYRRy" name="Hydroxypyruvate reductase (NADPH)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9380.1)</p>            <p>SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_hpyr_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glyc_DASH_DASH_DASH_R_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HPYRtp" name="hydroxypyruate transport, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hpyr_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hpyr_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD11B1r" name=" 11-beta-hydroxysteroid dehydrogenase type 1" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3290.2) or (3290.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cortsn_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crtsl_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD11B2r" name=" 11-beta-hydroxysteroid dehydrogenase type 2" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3291.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cortsn_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadh_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crtsl_r" stoichiometry="1"/>          <speciesReference species="M_nad_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD17B1" name="testicular 17-beta-hydroxysteroid dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3292.1) or (7923.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estrone_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estradiol_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD17B42x" name="hydroxysteroid (17-beta) dehydrogenase 4" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadph_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>          <speciesReference species="M_thcholoylcoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhocholoylcoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="2"/>          <speciesReference species="M_nadp_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD17B4x" name="hydroxysteroid (17-beta) dehydrogenase 4" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3295.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cholcoads_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadph_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cholcoaone_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nadp_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD17B7r" name="testicular 17-beta-hydroxysteroid dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51478.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estrone_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estradiol_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD17B8r" name=" 17-beta-hydroxysteroid dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3294.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estrone_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadh_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estradiol_r" stoichiometry="1"/>          <speciesReference species="M_nad_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD17B9r" name=" 17-beta-hydroxysteroid dehydrogenase (type 7)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51478.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_andrstrn_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1.5"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_eandrstrn_r" stoichiometry="1"/>          <speciesReference species="M_h2o_r" stoichiometry="2"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD3A1r" name=" 3 alpha-hydroxysteroid dehydrogenase (type 3)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1109.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_andrstandn_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadh_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_andrstrn_r" stoichiometry="1"/>          <speciesReference species="M_nad_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD3A2r" name=" 3 alpha-hydroxysteroid dehydrogenase (type 3)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1109.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_andrstandn_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_andrstrn_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD3B3r" name=" 3 beta-hydroxysteroid dehydrogenase type 1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3284.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_eandrstrn_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_andrstandn_r" stoichiometry="1"/>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD3B7" name="hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (80270.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nad_r" stoichiometry="1"/>          <speciesReference species="M_xol7a_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadh_r" stoichiometry="1"/>          <speciesReference species="M_xol7aone_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HSD3B7P" name="hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (80270.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_xol7a_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_xol7aone_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HTAXOLte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_htaxol_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_htaxol_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HXANtx" name="hypoxanthine diffusion in peroxisome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hxan_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hxan_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HXPRT" name="hypoxanthine phosphoribosyltransferase (Hypoxanthine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3251.1)</p>            <p>SUBSYSTEM: Salvage Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hxan_c" stoichiometry="1"/>          <speciesReference species="M_prpp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_imp_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HYPOE" name="hypothetical enyme" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (57026.1)</p>            <p>SUBSYSTEM: Vitamin B6 Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pyam5p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_pydam_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_HYPTROX" name="Hypotaurine oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Taurine and hypotaurine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_hyptaur_c" stoichiometry="2"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_taur_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_Htm" name="Uncoupling protein" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9016.1) or (7352.2) or (7352.1) or (7351.1) or (9016.2) or (7350.1) or (9481.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ICDHxm" name="Isocitrate dehydrogenase (NAD+)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3421.2 and 3420.3 and 3419.1) or (3420.1 and 3421.1 and 3419.1) or (3420.1 and 3421.1 and 3419.1) or (3420.3 and 3421.1 and 3419.1) or (3421.1 and 3419.1 and 3420.2) or (3421.2 and 3419.1 and 3420.2)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_icit_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ICDHy" name="isocitrate dehydrogenase (NADP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3417.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_icit_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_akg_c" stoichiometry="1"/>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ICDHyrm" name="Isocitrate dehydrogenase (NADP+)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3418.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_icit_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_IDPtn" name="IDP nuclear transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_idp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_idp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ILETAm" name="isoleucine transaminase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (587.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_ile_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3mop_m" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ILEt5m" name="Isoleucine mitochondrial transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ile_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ile_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ILEtec" name="L-isoleucine transport via diffusion (extracellular to cytosol)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8501.1) or (124935.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ile_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ile_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_IMPC" name="IMP cyclohydrolase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (471.1)</p>            <p>SUBSYSTEM: IMP Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_imp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fprica_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_IMPD" name="IMP dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3614.1) or (3615.1) or (3614.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_imp_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_xmp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_INSTt2r" name="inositol transport in via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (114134.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_inost_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_inost_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_INSTt4" name="inositol transport via sodium symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6526.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_inost_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_inost_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_INSt" name="Inosine transport (diffusion)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3177.1) or (2030.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ins_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ins_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_INSt5" name="inosine transport in via sodium (1:2) symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (64078.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ins_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ins_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_IPDDIx" name="isopentenyl-diphosphate D-isomerase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3422.1) or (91734.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ipdp_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dmpp_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ITCOAL1m" name="Itaconate--CoA ligase (GDP-forming), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8802.1 and 8801.1)</p>            <p>SUBSYSTEM: C5-Branched dibasic acid metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_gtp_m" stoichiometry="1"/>          <speciesReference species="M_itacon_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gdp_m" stoichiometry="1"/>          <speciesReference species="M_itaccoa_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ITCOALm" name="Itaconate--CoA ligase (ADP-forming), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8802.1 and 8803.1)</p>            <p>SUBSYSTEM: C5-Branched dibasic acid metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_itacon_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_itaccoa_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ITPtn" name="ITP nuclear transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_itp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_itp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_IZPN" name="imidazolonepropionase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Histidine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4izp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_forglu_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_KAS8" name="b-ketoacyl synthetase (palmitate, n-C16:0)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2194.1)</p>            <p>SUBSYSTEM: Fatty acid elongation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_accoa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="20"/>          <speciesReference species="M_malcoa_c" stoichiometry="7"/>          <speciesReference species="M_nadph_c" stoichiometry="14"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="7"/>          <speciesReference species="M_coa_c" stoichiometry="8"/>          <speciesReference species="M_h2o_c" stoichiometry="6"/>          <speciesReference species="M_hdca_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="14"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_KCC2t" name="K+-Cl- cotransporter (NH4+)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6560.1) or (10723.1) or (9990.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cl_e" stoichiometry="1"/>          <speciesReference species="M_nh4_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cl_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_KCCt" name="K+-Cl- cotransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10723.1) or (57468.1) or (9990.1) or (6560.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cl_e" stoichiometry="1"/>          <speciesReference species="M_k_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cl_c" stoichiometry="1"/>          <speciesReference species="M_k_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_KDNH" name=" 2-keto-3deoxy-D-glycero-D-galactononic acid phosphohydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_kdnp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_kdn_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_KHK" name="ketohexokinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3795.1) or (3795.2)</p>            <p>SUBSYSTEM: Fructose and Mannose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_fru_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_f1p_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_KHK2" name="ketohexokinase (D-xylulose)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3795.1) or (3795.2)</p>            <p>SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_xylu_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_xu1p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_KHK3" name="ketohexokinase (D-tagatose)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3795.1) or (3795.2)</p>            <p>SUBSYSTEM: Galactose metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_tagat_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_tag1p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_KYN3OX" name="kynurenine 3-monooxygenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8564.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Lkynr_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_hLkynr_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LALDD" name="D-lactaldehyde dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9380.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lald_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mthgxl_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LALDO" name="D-Lactaldehyde:NAD+ oxidoreductase (glutathione-formylating)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (128.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthrd_c" stoichiometry="1"/>          <speciesReference species="M_lald_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lgt_DASH_DASH_DASH_S_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LALDO2" name="D-Lactaldehyde:NADP+ 1-oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10327.1) or (8574.1) or (10327.2) or (231.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mthgxl_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lald_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LALDO2x" name="D-Lactaldehyde:NAD+ 1-oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8574.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mthgxl_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lald_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LCADi" name="lactaldehyde dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (218.1) or (223.1) or (8854.2) or (224.1) or (222.1) or (8854.1) or (221.1) or (216.1) or (8854.3) or (501.1) or (220.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_lald_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_lac_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LCADi_D" name="lactaldehyde dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (218.1) or (223.1) or (8854.2) or (224.1) or (222.1) or (8854.1) or (221.1) or (216.1) or (8854.3) or (501.1) or (220.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_lald_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_lac_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LCAT1e" name="Lecithin-cholesterol acyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3931.1)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chsterol_e" stoichiometry="1"/>          <speciesReference species="M_pchol_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lpchol_DASH_hs_e" stoichiometry="1"/>          <speciesReference species="M_xolest2_DASH_hs_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LCYSTAT" name="L-Cysteate:2-oxoglutarate aminotransferase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2805.1)</p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Lcyst_c" stoichiometry="1"/>          <speciesReference species="M_akg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3spyr_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LCYSTCBOXL" name=" 3-Sulfoalanine carboxy-lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51380.1) or (2571.1) or (2572.1) or (2571.2)</p>            <p>SUBSYSTEM: Taurine and hypotaurine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Lcyst_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_taur_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LDH_D" name="D-lactate dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (197257.1) or (197257.2)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lac_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LDH_L" name="L-lactate dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3945.1 and 3939.1) or (160287.1) or (3948.2) or (3939.1) or (3948.1) or (55293.1) or (3945.1) or (92483.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lac_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LDH_Lm" name="L-lactate dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3939.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lac_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_pyr_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LEUKTRA4tr" name="leukotriene intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_leuktrA4_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_leuktrA4_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LEUKTRC4t" name="leukotriene C4 transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10599.1) or (28234.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hco3_c" stoichiometry="1"/>          <speciesReference species="M_leuktrC4_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hco3_e" stoichiometry="1"/>          <speciesReference species="M_leuktrC4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LEUKTRD4tr" name="leukotriene intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_leuktrD4_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_leuktrD4_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LEUTAm" name="leucine transaminase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (587.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_leu_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4mop_m" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LEUt4" name="L-leucine transport in via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (81539.1) or (84889.1) or (6520.1) or (6542.1) or (6541.1) or (11254.1) or (55089.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_leu_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_leu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LEUt5m" name="leucine mitochondrial transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_leu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_leu_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LEUtec" name="L-leucine transport via diffusion (extracellular to cytosol)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8501.1) or (124935.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_leu_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_leu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LGNCCOAtx" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lgnccoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lgnccoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LGTHL" name="lactoylglutathione lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2739.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthrd_c" stoichiometry="1"/>          <speciesReference species="M_mthgxl_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lgt_DASH_DASH_DASH_S_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LIMNENte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_limnen_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_limnen_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNELDCCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_lneldccoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_lneldccrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNELDCCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_lneldccrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_lneldccoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNELDCCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lneldccrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lneldccrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNELDCt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lneldc_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lneldc_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLCCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_lnlccoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_lnlccrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLCCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_lnlccrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_lnlccoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLCCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lnlccrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lnlccrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLCt" name="Linoleic acid (n-C18:2) transport in via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lnlc_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lnlc_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLNCACPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_lnlncacoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_lnlncacrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLNCACPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_lnlncacrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_lnlncacoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLNCACRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lnlncacrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lnlncacrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLNCAt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lnlnca_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lnlnca_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLNCGCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_lnlncgcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_lnlncgcrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLNCGCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_lnlncgcrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_lnlncgcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLNCGCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lnlncgcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lnlncgcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNLNCGt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lnlncg_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lnlncg_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNS14DMr" name="cytochrome P450 lanosterol 14-alpha-demethylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1595.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_r" stoichiometry="2"/>          <speciesReference species="M_lanost_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="3"/>          <speciesReference species="M_o2_r" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_44mctr_r" stoichiometry="1"/>          <speciesReference species="M_for_r" stoichiometry="1"/>          <speciesReference species="M_h2o_r" stoichiometry="4"/>          <speciesReference species="M_nadp_r" stoichiometry="3"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LNSTLSr" name="lanosterol synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4047.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Ssq23epx_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lanost_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LPASE" name="lysophospholipase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5321.1) or (1178.1) or (29124.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_lpchol_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal_c" stoichiometry="1"/>          <speciesReference species="M_g3pc_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LPCOXp" name="L-pipecolate oxidase, peroxisomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51268.1)</p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Lpipecol_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_thp2c_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LPS" name="lipase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4023.1)</p>            <p>SUBSYSTEM: Triacylglycerol Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_tag_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal3_c" stoichiometry="1"/>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LPS2" name="lipase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4023.1)</p>            <p>SUBSYSTEM: Triacylglycerol Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mag_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LPS2e" name="lipase, extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3990.1)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dag_DASH_hs_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_mag_DASH_hs_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LPS3" name="lipase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11343.1) or (11343.2)</p>            <p>SUBSYSTEM: Triacylglycerol Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mag_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal2_c" stoichiometry="1"/>          <speciesReference species="M_glyc_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LPS3e" name="lipase, extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3990.1)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_e" stoichiometry="1"/>          <speciesReference species="M_mag_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal2_e" stoichiometry="1"/>          <speciesReference species="M_glyc_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LPSe" name="lipase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3990.1) or (9388.1) or (5407.1) or (8513.1) or (5408.1) or (5406.1)</p>            <p>SUBSYSTEM: Triacylglycerol Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_e" stoichiometry="1"/>          <speciesReference species="M_tag_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal3_e" stoichiometry="1"/>          <speciesReference species="M_dag_DASH_hs_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LSTO1r" name="Lathosterol oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6309.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chlstol_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ddsmsterol_r" stoichiometry="1"/>          <speciesReference species="M_h2o_r" stoichiometry="2"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LSTO2r" name="Lathosterol oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6309.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_lthstrl_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_7dhchsterol_r" stoichiometry="1"/>          <speciesReference species="M_h2o_r" stoichiometry="2"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LTC4CP" name="Leukotriene C4 carboxypeptidase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Eicosanoid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_leuktrC4_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gly_c" stoichiometry="1"/>          <speciesReference species="M_leuktrF4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LTC4Sr" name="Leukotriene C4 synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4056.1) or (4259.1) or (4056.2) or (4258.1)</p>            <p>SUBSYSTEM: Eicosanoid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gthrd_r" stoichiometry="1"/>          <speciesReference species="M_leuktrA4_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_leuktrC4_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LTD4DP" name="Leukotriene D4 dipeptidase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Eicosanoid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_leuktrD4_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gly_c" stoichiometry="1"/>          <speciesReference species="M_leuktrE4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LYSOXp" name="L-lysine oxidase, peroxisomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_lys_DASH_DASH_DASH_L_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6a2ohxnt_x" stoichiometry="1"/>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_nh4_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LYStiDF" name="L-lysine transport via diffusion (extracellular to cytosol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6541.1) or (6542.1) or (55089.1) or (84889.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lys_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LYStip" name="L-lysine transport, peroxisomal (irreversible)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lys_DASH_DASH_DASH_L_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LYStm" name="Lysine mitochondrial transport via ornithine carrier" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (83884.1) or (10166.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_lys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lys_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_LYStn" name="L-lysine transport, nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lys_DASH_DASH_DASH_L_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_L_LACDcm" name="L-Lactate dehydrogenase, cytosolic/mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (124637.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ficytC_m" stoichiometry="2"/>          <speciesReference species="M_lac_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_focytC_m" stoichiometry="2"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_L_LACt2r" name="L-lactate reversible transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9194.1) or (23539.1) or (6566.1) or (9123.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_lac_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lac_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_L_LACt4r" name="L-lactate reversible transport via sodium symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lac_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lac_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_L_LACtcm" name="L-lactate transport via diffusion (cytosol to mitochondria)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (366.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_lac_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_lac_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_L_LACtm" name="L-lactate transport, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6566.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lac_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_lac_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MACACI" name="maleylacetoacetate isomerase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2954.1) or (2954.3) or (2954.2)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4mlacac_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4fumacac_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MACOXO" name=" 3-Methylimidazole acetaldehyde:NAD+ oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (218.1) or (221.1) or (4129.1) or (222.1) or (220.1)</p>            <p>SUBSYSTEM: Histidine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3mldz_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3mlda_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MALSO3tm" name="Malate:sulfite antiport, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1468.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mal_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_so3_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mal_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_so3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MALT" name="alpha-glucosidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2595.1)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_malt_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glc_DASH_DASH_DASH_D_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MALTSULtm" name="Malate:thiosulfate antiport, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1468.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mal_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_tsul_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mal_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_tsul_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MALTt1r" name="maltose transport (uniport)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6515.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_malt_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_malt_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MANt1r" name="mannose transport (uniport)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6513.1) or (6515.1) or (6514.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_man_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_man_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MANt4" name="D-mannose transport via sodium cotransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (200010.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_man_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_man_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MANtly" name="mannose efflux from lysosome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_man_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_man_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MAOX" name="Methylamine oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8639.1) or (26.1) or (314.2) or (314.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mma_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fald_c" stoichiometry="1"/>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MCCCrm" name="methylcrotonoyl-CoA carboxylase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (56922.1 and 64087.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3mb2coa_m" stoichiometry="1"/>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_hco3_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3mgcoa_m" stoichiometry="1"/>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MCD" name="Malonyl-CoA Decarboxylase cytoplasmic" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23417.1)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_malcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_c" stoichiometry="1"/>          <speciesReference species="M_co2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MCDm" name="Malonyl-CoA Decarboxylase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23417.1)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_malcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MCITS" name=" 2-methylcitrate synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Propanoate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_oaa_c" stoichiometry="1"/>          <speciesReference species="M_ppcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2mcit_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MCLACCYSR" name=" 3-mercaptolactate:cysteine reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_mercplac_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mercplaccys_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MCLOR" name=" 3-Mercaptolactate:NAD+ oxidoreductase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (92483.1) or (3945.1 and 3939.1) or (55293.1) or (3948.2) or (3948.1) or (3945.1) or (160287.1) or (3939.1)</p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mercplac_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mercppyr_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MCPST" name=" 3-mercaptopyruvate sulfurtransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4357.1)</p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cyan_c" stoichiometry="1"/>          <speciesReference species="M_mercppyr_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>          <speciesReference species="M_tcynt_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MDH" name="malate dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (130752.1) or (4190.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mal_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_oaa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MDHm" name="malate dehydrogenase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4191.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mal_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_oaa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MDRPD" name=" 5-Methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5mdru1p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dkmpp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ME1m" name="malic enzyme (NAD), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4200.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mal_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_pyr_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ME2" name="malic enzyme (NADP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4199.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mal_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ME2m" name="malic enzyme (NADP), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4200.1) or (10873.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mal_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>          <speciesReference species="M_pyr_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MECOALm" name="mesaconate--CoA ligase (ADP-forming), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8802.1 and 8803.1)</p>            <p>SUBSYSTEM: C5-Branched dibasic acid metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_mescon_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_mescoa_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MECOAS1m" name="mesaconate--CoA ligase (GDP-forming)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8802.1 and 8801.1)</p>            <p>SUBSYSTEM: C5-Branched dibasic acid metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_gtp_m" stoichiometry="1"/>          <speciesReference species="M_mescon_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gdp_m" stoichiometry="1"/>          <speciesReference species="M_mescoa_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MERCPLACCYSt" name=" 3-mercaptolactate-cysteine disulfide transport, extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mercplaccys_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mercplaccys_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_METAT" name="methionine adenosyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4143.1) or (27430.2 and 4144.1) or (27430.1 and 4144.1)</p>            <p>SUBSYSTEM: Methionine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_met_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amet_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_METS" name="methionine synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4548.1)</p>            <p>SUBSYSTEM: Methionine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5mthf_c" stoichiometry="1"/>          <speciesReference species="M_hcys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_met_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_METt4" name="L-methionine transport in via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (81539.1) or (11254.1) or (54407.1) or (6584.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_met_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_met_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_METtec" name="L-methionine transport via diffusion (extracellular to cytosol)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8501.1) or (124935.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_met_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_met_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MEVK1x" name="mevalonate kinase (atp)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4598.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_x" stoichiometry="1"/>          <speciesReference species="M_mev_DASH_DASH_DASH_R_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5pmev_x" stoichiometry="1"/>          <speciesReference species="M_adp_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MGCHrm" name="methylglutaconyl-CoA hydratase (reversible), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (549.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3mgcoa_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hmgcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MHISOR" name="N-Methylhistamine:oxygen oxidoreductase (deaminating)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (26.1) or (314.1) or (8639.1) or (314.2)</p>            <p>SUBSYSTEM: Histidine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mhista_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3mldz_c" stoichiometry="1"/>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI1345PP" name="inositol-1,3,4,5-trisphosphate 5-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3635.1) or (8867.2) or (3636.1) or (27124.2) or (8867.1) or (27124.1) or (3633.1) or (56623.1) or (3632.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mi1345p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mi134p_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI134PP" name="inositol-1,3,4-trisphosphate 1-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3628.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mi134p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mi34p_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI145PK" name="inositol-1,4,5-trisphosphate 3-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3706.1) or (80271.1) or (3707.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_mi145p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mi1345p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI145PP" name="inositol-1,4,5-trisphosphate 5-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3635.1) or (8867.2) or (3636.1) or (27124.2) or (8867.1) or (27124.1) or (3633.1) or (56623.1) or (3632.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mi145p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mi14p_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI14PP" name="inositol-1,4-bisphosphate 1-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3628.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mi14p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mi4p_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI14Ptn" name="inositol 1,4-bisphosphate nuclear transport (diffusion)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mi14p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mi14p_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI1PP" name="myo-inositol 1-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3612.1) or (3613.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mi1p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_inost_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI1P_Dtn" name="inositol 1-phosphate nuclear transport (diffusion)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mi1p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mi1p_DASH_DASH_DASH_D_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI34PP" name="inositol-3,4-bisphosphate 4-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3631.2) or (3631.1) or (8821.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mi34p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mi3p_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI3PP" name="myo-inositol 3-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3612.1) or (3613.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mi3p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_inost_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MI4PP" name="myo-inositol 4-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3612.1) or (3613.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_mi4p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_inost_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MMCDm" name="Methylmalonyl-CoA decarboxylase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23417.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_mmcoa_DASH_DASH_DASH_S_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_ppcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MMEm" name="methylmalonyl-CoA epimerase/racemase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (84693.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mmcoa_DASH_DASH_DASH_R_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_mmcoa_DASH_DASH_DASH_S_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MMMm" name="methylmalonyl-CoA mutase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4594.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mmcoa_DASH_DASH_DASH_R_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_succoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MMSAD1m" name="methylmalonate-semialdehyde dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4329.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2mop_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_ppcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MMSAD3m" name="methylmalonate-semialdehyde dehydrogenase (malonic semialdehyde), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4329.1)</p>            <p>SUBSYSTEM: Propanoate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_msa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MOGAT" name="monoacylglycerol acyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (116255.1) or (80168.1)</p>            <p>SUBSYSTEM: Triacylglycerol Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotalcoa_c" stoichiometry="1"/>          <speciesReference species="M_mag_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MTAP" name=" 5&apos;-methylthioadenosine phosphorylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4507.1)</p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5mta_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5mdr1p_c" stoichiometry="1"/>          <speciesReference species="M_ade_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MTHFC" name="methenyltetrahydrofolate cyclohydrolase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4522.1) or (285216.1) or (80068.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_methf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MTHFCm" name="methenyltetrahydrifikate cyclohydrolase, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (25902.1) or (10797.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_methf_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_10fthf_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MTHFD" name="methylenetetrahydrofolate dehydrogenase (NADP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4522.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mlthf_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_methf_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MTHFD2" name="methylenetetrahydrofolate dehydrogenase (NAD)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (285216.1) or (80068.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mlthf_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_methf_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MTHFDm" name="methylenetetrahydrofolate dehydrogenase (NADP), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (25902.1) or (10797.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_mlthf_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_methf_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MTHFR3" name=" 5,10-methylenetetrahydrofolatereductase (NADPH)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4524.1)</p>            <p>SUBSYSTEM: Folate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_mlthf_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5mthf_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_MTRI" name=" 5-methylthioribose-1-phosphate isomerase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5mdr1p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5mdru1p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_N2M2NMASNtly" name="n2m2nmasn transport, extracellular to lysosome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_n2m2nmasn_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_n2m2nmasn_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NACHEX27ly" name="beta-N-acetylhexosaminidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3073.1 and 3074.1) or (3073.1) or (3074.1)</p>            <p>SUBSYSTEM: Hyaluronan Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="1"/>          <speciesReference species="M_ha_DASH_deg1_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acgam_l" stoichiometry="1"/>          <speciesReference species="M_ha_DASH_pre1_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NACUP" name="Nicotinic acid uptake" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nac_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nac_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NADN" name="NAD nucleosidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adprib_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_ncam_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NADPHtru" name="NADPH transporter, endoplasmic reticulum" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NADPHtxu" name="NADPH transporter, peroxisome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadph_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NADPtru" name="NADP transporter, endoplasmic reticulum" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NADPtxu" name="NADP transporter, peroxisome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadp_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NADS2" name="NAD synthase (glutamine-hydrolysing)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55191.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dnad_c" stoichiometry="1"/>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NADtn" name="NAD transport, nuclear through pores" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nad_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NAt" name="sodium transport (uniport)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6526.1) or (6523.1) or (6528.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NAt3_1" name="sodium proton antiporter (H:NA is 1:1)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (389015.1) or (6548.1) or (6550.1) or (6549.1) or (6553.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NAtx" name="sodium transport via diffusion (perioxisome)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDP10ex" name="nucleoside-diphosphatase (IDP), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (124583.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_e" stoichiometry="1"/>          <speciesReference species="M_idp_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_imp_e" stoichiometry="1"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDP3ex" name="nucleoside-diphosphatase (GDP), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (124583.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gdp_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gmp_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDP7ex" name="nucleoside-diphosphatase (UDP), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (124583.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_e" stoichiometry="1"/>          <speciesReference species="M_udp_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>          <speciesReference species="M_ump_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDP8" name="nucleoside-diphosphatase (dUDP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1841.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dudp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dump_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDP8ex" name="nucleoside-diphosphatase (UTP), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (124583.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_e" stoichiometry="1"/>          <speciesReference species="M_utp_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>          <speciesReference species="M_udp_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK1" name="nucleoside-diphosphate kinase (ATP:GDP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4832.1) or (10201.1) or (4831.1 and 4830.1) or (29922.2) or (4831.1 and 4830.2) or (29922.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_gdp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_gtp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK10" name="nucleoside-diphosphate kinase (ATP:dIDP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4832.1) or (4831.1 and 4830.1) or (10201.1) or (29922.2) or (29922.1) or (4831.1 and 4830.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_didp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_ditp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK10n" name="nucleoside-diphosphate kinase (ATP:dIDP), nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_didp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_ditp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK1m" name="nucleoside-diphosphate kinase (ATP:GDP), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4833.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_gdp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_gtp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK1n" name="nucleoside-diphosphate kinase (ATP:GDP), nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_gdp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_gtp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK2" name="nucleoside-diphosphate kinase (ATP:UDP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4832.1) or (29922.1) or (4831.1 and 4830.1) or (10201.1) or (4831.1 and 4830.2) or (29922.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_utp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK2n" name="nucleoside-diphosphate kinase (ATP:UDP), nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_udp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_utp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK3" name="nucleoside-diphosphate kinase (ATP:CDP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4832.1) or (29922.2) or (4831.1 and 4830.1) or (29922.1) or (10201.1) or (4831.1 and 4830.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_cdp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_ctp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK3m" name="nucleoside-diphosphate kinase (ATP:CDP), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4833.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_cdp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_ctp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK3n" name="nucleoside-diphosphate kinase (ATP:CDP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_cdp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_ctp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK4" name="nucleoside-diphosphate kinase (ATP:dTDP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4832.1) or (4831.1 and 4830.1) or (10201.1) or (29922.2) or (29922.1) or (4831.1 and 4830.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dtdp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_dttp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK4m" name="nucleoside-diphosphate kinase (ATP:dTDP), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4833.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_dtdp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_dttp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK4n" name="nucleoside-diphosphate kinase (ATP:dTDP), nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_dtdp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_dttp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK5" name="nucleoside-diphosphate kinase (ATP:dGDP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4832.1) or (4831.1 and 4830.2) or (10201.1) or (29922.2) or (29922.1) or (4831.1 and 4830.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dgdp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_dgtp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK5m" name="nucleoside-diphosphate kinase (ATP:dGDP), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4833.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_dgdp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_dgtp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK5n" name="nucleoside-diphosphate kinase (ATP:dGDP), nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_dgdp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_dgtp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK6" name="nucleoside-diphosphate kinase (ATP:dUDP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4832.1) or (4831.1 and 4830.1) or (10201.1) or (29922.2) or (29922.1) or (4831.1 and 4830.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dudp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_dutp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK6m" name="nucleoside-diphosphate kinase (ATP:dUDP), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4833.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_dudp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_dutp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK6n" name="nucleoside-diphosphate kinase (ATP:dUDP), nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_dudp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_dutp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK7" name="nucleoside-diphosphate kinase (ATP:dCDP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4832.1) or (4831.1 and 4830.1) or (10201.1) or (29922.2) or (29922.1) or (4831.1 and 4830.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_dctp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK7m" name="nucleoside-diphosphate kinase (ATP:dCDP), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4833.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_dcdp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_dctp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK7n" name="nucleoside-diphosphate kinase (ATP:dCDP), nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_dcdp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_dctp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK8" name="nucleoside-diphosphate kinase (ATP:dADP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4832.1) or (4831.1 and 4830.1) or (10201.1) or (29922.2) or (29922.1) or (4831.1 and 4830.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_dadp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_datp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK8m" name="nucleoside-diphosphate kinase (ATP:dADP), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4833.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_dadp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_datp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK8n" name="nucleoside-diphosphate kinase (ATP:dADP), nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_dadp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_datp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK9" name="nucleoside-diphosphate kinase (ATP:IDP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4832.1) or (4831.1 and 4830.1) or (10201.1) or (29922.2) or (29922.1) or (4831.1 and 4830.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_idp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_itp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NDPK9n" name="nucleoside-diphosphate kinase (ATP:IDP), nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_idp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_itp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NH4tp" name="ammonia peroxisomal transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nh4_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NICRNS" name="NICRNS" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_nicrns_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nicrnt_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NICRNTtn" name="NICRNT transport, nuclear trhough pore" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nicrnt_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nicrnt_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NKCC2t" name="Na+-K+-Cl- cotransport (NH4+)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6557.1) or (6558.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cl_e" stoichiometry="2"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_nh4_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cl_c" stoichiometry="2"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NKCCt" name="Na+-K+-Cl- cotransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6557.1) or (6558.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cl_e" stoichiometry="2"/>          <speciesReference species="M_k_e" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cl_c" stoichiometry="2"/>          <speciesReference species="M_k_c" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NMNATn" name="nicotinamide-nucleotide adenylyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (64802.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_h_n" stoichiometry="1"/>          <speciesReference species="M_nmn_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nad_n" stoichiometry="1"/>          <speciesReference species="M_ppi_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NMNtn" name="NMN transport, nuclear trhough pore" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nmn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nmn_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NNAT" name="nicotinate-nucleotide adenylyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5167.1) or (5169.1) or (5168.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nicrnt_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dnad_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NNATn" name="nicotinate-nucleotide adenylyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (64802.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_h_n" stoichiometry="1"/>          <speciesReference species="M_nicrnt_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dnad_n" stoichiometry="1"/>          <speciesReference species="M_ppi_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NNDPR" name="nicotinate-nucleotide diphosphorylase (carboxylating)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23475.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_prpp_c" stoichiometry="1"/>          <speciesReference species="M_quln_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_nicrnt_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NNMT" name="Nicotinamide N-methyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4837.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amet_c" stoichiometry="1"/>          <speciesReference species="M_ncam_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_1mncam_c" stoichiometry="1"/>          <speciesReference species="M_ahcys_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NORANMT" name="noradrenaline N-methyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5409.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amet_c" stoichiometry="1"/>          <speciesReference species="M_nrpphr_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adrnl_c" stoichiometry="1"/>          <speciesReference species="M_ahcys_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NOS1" name="Nitric Oxide Synthase (intermediate forming)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4846.1) or (4844.1) or (4842.1) or (4843.2) or (4843.1) or (4845.1)</p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_arg_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_nwharg_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NOS2" name="Nitric Oxide Synthase (NO forming)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4846.1) or (4844.1) or (4842.1) or (4843.2) or (4843.1) or (4845.1)</p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_nwharg_c" stoichiometry="2"/>          <speciesReference species="M_o2_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_citr_DASH_DASH_DASH_L_c" stoichiometry="2"/>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_no_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NOt" name="NO transport (diffusion)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_no_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_no_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NP1" name="nucleotide phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4860.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nac_c" stoichiometry="1"/>          <speciesReference species="M_r1p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nicrns_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NRPPHRSFt" name="norepinephrine sulfate transport (diffusion)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nrpphrsf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nrpphrsf_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NRPPHRSULT" name="Norepinephrine Sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6818.1) or (6818.3) or (6818.2)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nrpphr_c" stoichiometry="1"/>          <speciesReference species="M_paps_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nrpphrsf_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NRPPHRVESSEC" name="Noradrenaline secretion via secretory vesicle (ATP driven)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6570.1) or (6571.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="2"/>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_nrpphr_c" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="2"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nrpphr_e" stoichiometry="3"/>          <speciesReference species="M_pi_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NRPPHRtu" name="Norepinephrine uniport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6581.1) or (6582.2) or (6582.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nrpphr_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nrpphr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NRVNCCOAtx" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nrvnccoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nrvnccoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NT5C" name=" 5&apos;-nucleotidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22978.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nicrnt_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nicrns_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD10" name=" 5&apos;-nucleotidase (XMP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22978.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_xmp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_xtsn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD11" name=" 5&apos;-nucleotidase (IMP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22978.1) or (93034.2) or (93034.1)</p>            <p>SUBSYSTEM: Purine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_imp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ins_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD1m" name=" 5&apos;-nucleotidase (dUMP),mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (56953.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dump_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_duri_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD2" name=" 5&apos;-nucleotidase (UMP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51251.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_uri_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD2e" name=" 5&apos;-nucleotidase (UMP), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4907.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_e" stoichiometry="1"/>          <speciesReference species="M_ump_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_e" stoichiometry="1"/>          <speciesReference species="M_uri_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD3" name=" 5&apos;-nucleotidase (dCMP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (93034.1) or (30833.1) or (93034.2)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dcmp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcyt_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD4" name=" 5&apos;-nucleotidase (CMP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51251.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cytd_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD4e" name=" 5&apos;-nucleotidase (CMP), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4907.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmp_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cytd_e" stoichiometry="1"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD5m" name=" 5&apos;-nucleotidase (dTMP), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (56953.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dtmp_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_m" stoichiometry="1"/>          <speciesReference species="M_thymd_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD6" name=" 5&apos;-nucleotidase (dAMP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22978.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_damp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dad_DASH_DASH_DASH_2_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD7" name=" 5&apos;-nucleotidase (AMP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22978.1) or (93034.2) or (93034.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adn_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD7e" name=" 5&apos;-nucleotidase (AMP), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4907.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amp_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adn_e" stoichiometry="1"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD8" name=" 5&apos;-nucleotidase (dGMP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22978.1) or (30833.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dgmp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dgsn_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD9" name=" 5&apos;-nucleotidase (GMP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22978.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gmp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gsn_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTD9e" name=" 5&apos;-nucleotidase (GMP), extracellular" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4907.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gmp_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gsn_e" stoichiometry="1"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NTP3e" name="nucleoside-triphosphatase (GTP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (124583.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gtp_e" stoichiometry="1"/>          <speciesReference species="M_h2o_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gdp_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_NaKt" name="Na+/K+ exchanging ATPase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (481.1 and 478.1) or (477.1 and 23439.1) or (476.1 and 483.1) or (481.1 and 480.1) or (482.1 and 478.1) or (482.1 and 476.1) or (482.1 and 477.1) or (481.1 and 476.1) or (23439.1 and 476.1) or (23439.1 and 480.1) or (481.1 and 477.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_k_e" stoichiometry="2"/>          <speciesReference species="M_na1_c" stoichiometry="3"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_k_c" stoichiometry="2"/>          <speciesReference species="M_na1_e" stoichiometry="3"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_O2St" name="superoxide anion transport via diffusion (extracellular)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2s_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_o2s_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_O2Stn" name="superoxide anion transport via diffusion (nucleus)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2s_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_o2s_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_O2Stx" name="superoxide anion transport via diffusion (peroxisome)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2s_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_o2s_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_O2ter" name="O2  transport, endoplasmic reticulum" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_o2_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_O2tm" name="O2 transport (diffusion)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_o2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_O2tn" name="O2 nuclear transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_o2_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OCBTm" name="ornithine carbamoyltransferase, irreversible" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5009.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cbp_m" stoichiometry="1"/>          <speciesReference species="M_orn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_citr_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OCCOAtm" name="Octanoyl-CoA transport, diffusion" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_occoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_occoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OCCOAtx" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_occoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_occoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OCTAt" name="Octanoate transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_octa_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_octa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ODECOAtx" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_odecoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_odecoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OIVD1m" name=" 2-oxoisovalerate dehydrogenase (acylating; 4-methyl-2-oxopentaoate), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1629.1) and (594.1 and 593.1) and (1738.1) or (1629.1) and (1738.1) and (594.2 and 593.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4mop_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_ivcoa_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OIVD2m" name=" 2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxobutanoate), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1629.1) and (594.1 and 593.1) and (1738.1) or (1629.1) and (1738.1) and (594.2 and 593.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3mob_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_ibcoa_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OIVD3m" name=" 2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxopentanoate), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1629.1) and (594.1 and 593.1) and (1738.1) or (1629.1) and (1738.1) and (594.2 and 593.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3mop_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2mbcoa_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OMEPRAZOLEte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_omeprazole_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_omeprazole_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OMPDC" name="orotidine-5&apos;-phosphate decarboxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7372.1)</p>            <p>SUBSYSTEM: Pyrimidine Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_orot5p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OPAHir" name=" 5-Oxoproline amidohydrolase (ATP-hydrolysing) (ir)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (26873.1)</p>            <p>SUBSYSTEM: Glutathione Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5oxpro_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ORNDC" name="Ornithine Decarboxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4953.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_orn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_ptrc_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ORNTArm" name="ornithine transaminase reversible (m)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4942.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_orn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu5sa_m" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ORNt3m" name="ornithine mitochondrial transport via proton antiport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (83884.1) or (10166.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_orn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_orn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ORNt4m" name="ornithine mitochondrial transport exchange with citruline" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10166.1) or (83884.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_citr_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_orn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_citr_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_orn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ORNtiDF" name="ornithine transport via diffusion (extracellular to cytosol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6542.1) or (6541.1) or (84889.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_orn_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_orn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_ORPT" name="orotate phosphoribosyltransferase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7372.1)</p>            <p>SUBSYSTEM: Pyrimidine Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_orot5p_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_orot_c" stoichiometry="1"/>          <speciesReference species="M_prpp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OXAHCOtex" name="oxalate transport via bicarbonate countertransport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1836.1) or (10861.1) or (10861.3) or (10861.2) or (1811.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hco3_c" stoichiometry="2"/>          <speciesReference species="M_oxa_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hco3_e" stoichiometry="2"/>          <speciesReference species="M_oxa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_OXAtp" name="oxalate transport out of peroxisome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_oxa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_oxa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4501B1r" name="cytochrome P450 1B1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1545.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estradiol_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_hestratriol_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P45027A11m" name=" 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1593.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>          <speciesReference species="M_xoltriol_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>          <speciesReference species="M_xoltetrol_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P45027A12m" name=" 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1593.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadp_m" stoichiometry="1"/>          <speciesReference species="M_xoltetrol_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>          <speciesReference species="M_thcholst_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P45027A13m" name=" 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1593.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadph_m" stoichiometry="1"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>          <speciesReference species="M_thcholst_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>          <speciesReference species="M_thcholstoic_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P45027A14m" name=" 5-beta-cytochrome P450, family 27, subfamily A, polypeptide 1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1593.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>          <speciesReference species="M_xol7ah2_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>          <speciesReference species="M_xol7ah3_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P45027A15m" name=" 5-beta-cytochrome P450, family 27, subfamily A, polypeptide 1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1593.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>          <speciesReference species="M_xol7ah3_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_m" stoichiometry="2"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>          <speciesReference species="M_xol7ah2al_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P45027A16m" name="Cytochrome P450 27" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1593.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadph_m" stoichiometry="1"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>          <speciesReference species="M_xol7ah2al_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhcholestanate_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P45027A1m" name="Cytochrome P450 27" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1593.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chsterol_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>          <speciesReference species="M_xol27oh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4502A6" name="cytochrome P450 2A6" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1553.1) or (1548.1)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coumarin_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_hcoumarin_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4502C18" name="cytochrome P450 2C18" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1562.1)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_antipyrene_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="0.5"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dmantipyrine_c" stoichiometry="1"/>          <speciesReference species="M_meoh_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4502C19" name="cytochrome P450 2C19" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1557.1)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_omeprazole_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5homeprazole_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4502C8" name="cytochrome P450 2C8" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1558.1) or (1558.2)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_taxol_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_htaxol_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4502C9" name="cytochrome P450 2C9" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1559.1)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_tolbutamide_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4mtolbutamide_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4502C92" name="cytochrome P450 2C9" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1559.1) or (1557.1)</p>            <p>SUBSYSTEM: Limonene and pinene degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_limnen_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_carveol_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4502C93" name="cytochrome P450 2C9" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1559.1) or (1557.1)</p>            <p>SUBSYSTEM: Limonene and pinene degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_limnen_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_perillyl_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4502C94" name="cytochrome P450 2C9" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1559.1) or (1557.1)</p>            <p>SUBSYSTEM: Limonene and pinene degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_appnn_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_apnnox_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4502D6" name="cytochrome P450 2D6" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1565.1)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_debrisoquine_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4hdebrisoquine_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4502E1" name="cytochrome P450 2E1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1571.1)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4nph_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_24nph_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P45039A1r" name="oxysterol 7-alpha-hydroxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51302.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>          <speciesReference species="M_xol24oh_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_xoltri24_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4503A5" name="cytochrome P450 3A5" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1577.1)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_aflatoxin_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_eaflatoxin_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P45046A1r" name="cytochrome P450, family 46, subfamily A, polypeptide 1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10858.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chsterol_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_xol24oh_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4504F123r" name="cytochrome p450 4F12/4F2" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (66002.1)</p>            <p>SUBSYSTEM: CYP Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ebastine_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ebastineoh_r" stoichiometry="1"/>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4507A1r" name="cytochrome P450, family 7, subfamily A, polypeptide 1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1581.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chsterol_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_xol7a_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4507B11r" name="oxysterol 7alpha-hydroxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9420.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>          <speciesReference species="M_xol25oh_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_xoltri25_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4507B12r" name="oxysterol 7alpha-hydroxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9420.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>          <speciesReference species="M_xol27oh_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_xoltri27_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4508B11r" name="sterol 12-alpha-hydroxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1582.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>          <speciesReference species="M_xol7aone_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_xoldiolone_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P4508B13r" name="sterol 12-alpha-hydroxylase (nadh)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1582.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadh_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>          <speciesReference species="M_xol7aone_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nad_r" stoichiometry="1"/>          <speciesReference species="M_xoldiolone_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P5CDm" name=" 1-pyrroline-5-carboxylate dehydrogenase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8659.1) or (8659.2)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_1pyr5c_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="2"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P5CRx" name="pyrroline-5-carboxylate reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (29920.1) or (65263.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_1pyr5c_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_pro_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_P5CRxm" name="pyrroline-5-carboxylate reductase (m)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5831.1) or (5831.2)</p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_1pyr5c_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nad_m" stoichiometry="1"/>          <speciesReference species="M_pro_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PACCOAL" name="phenylacetate-CoA ligase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Phenylalanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_pac_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_phaccoa_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PAFHe" name="Platelet-activating factor acetylhydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7941.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_e" stoichiometry="1"/>          <speciesReference species="M_paf_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ac_e" stoichiometry="1"/>          <speciesReference species="M_ak2lgchol_DASH_hs_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PAIL4P_HStn" name="phosphatidylinositol 4-phosphate nuclear transport (diffusion)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pail4p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pail4p_DASH_hs_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PAIL_HStn" name="phosphatidylinositol nuclear transport (diffusion)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pail_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pail_DASH_hs_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PAN4PP" name="phosphatase (pan4p)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: CoA Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pan4p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_ptth_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PA_HSter" name="phosphatidate scramblase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pa_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pa_DASH_hs_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PA_HStn" name="phosphatidate transport, nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pa_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pa_DASH_hs_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PCHOLPm_hs" name="choline phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5337.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_pchol_DASH_hs_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chol_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_pa_DASH_hs_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PCHOLPr_hs" name="choline phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5337.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_pchol_DASH_hs_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chol_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_pa_DASH_hs_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PCLAD" name="picolinic acid decarboxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (130013.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmusa_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_am6sa_c" stoichiometry="1"/>          <speciesReference species="M_co2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PCREATtmdiffir" name="Phosphocreatine transport to/from mitochondria via diffusion" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pcreat_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pcreat_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PCRNtm" name="transport into the mitochondria from cytosol (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PCm" name="pyruvate carboxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5091.1) or (5091.2)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_hco3_m" stoichiometry="1"/>          <speciesReference species="M_pyr_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_oaa_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PCt" name="phosphatidylcholine transporter" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5244.1) or (5244.3) or (5244.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pchol_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pchol_DASH_hs_e" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PDE1" name=" 3&apos;,5&apos;-cyclic-nucleotide phosphodiesterase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5139.1) or (5142.1) or (5151.2) or (5153.1) or (5150.2) or (5143.1) or (5150.1) or (5137.1) or (5144.1) or (5136.2) or (5140.2) or (8622.1) or (10846.1) or (5151.4) or (5140.1) or (5141.1) or (5138.1) or (5136.1) or (5151.3) or (50940.1) or (27115.1) or (5151.5) or (5151.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_camp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PDE4" name=" 3&apos;,5&apos;-cyclic-nucleotide phosphodiesterase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5139.1) or (5146.1) or (5152.19) or (8654.1) or (5152.4) or (5136.1) or (5152.13) or (50940.1) or (8654.3) or (10846.1) or (5152.12) or (5145.1 and 5158.1 and 5149.1) or (5140.1) or (5152.14) or (5152.17) or (5137.1) or (5136.2) or (5138.1) or (5152.3) or (5153.1) or (8654.2) or (5152.6) or (5152.18) or (5152.10) or (5152.16) or (5152.15) or (5152.5) or (5152.2) or (5140.2) or (5152.11) or (5152.7) or (5145.1 and 5146.1 and 5147.1 and 5158.1 and 5148.1) or (5152.20)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_35cgmp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gmp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PDHm" name="pyruvate dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1738.1 and 8050.1) and (5161.1 and 5162.1) and (1737.1) or (1738.1 and 8050.1) and (5160.1 and 5162.1) and (1737.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>          <speciesReference species="M_pyr_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_accoa_m" stoichiometry="1"/>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PDX5PO" name="pyridoxine 5&apos;-phosphate oxidase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55163.1)</p>            <p>SUBSYSTEM: Vitamin B6 Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_pdx5p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_pydx5p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PDXPP" name="Pyridoxine 5-phosphate phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (57026.1)</p>            <p>SUBSYSTEM: Vitamin B6 Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pdx5p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_pydxn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PEAMNO" name="Phenethylamine oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (314.1) or (4128.1) or (26.1) or (4129.1) or (314.2)</p>            <p>SUBSYSTEM: Phenylalanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_peamn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>          <speciesReference species="M_pacald_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PEFLIP" name="phosphatidylethanolamine flippase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10396.1) or (57194.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pe_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pe_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PEFLIPm" name="phosphatidylethanolamine flippase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10396.1) or (57194.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pe_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pe_DASH_hs_m" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PEPCK" name="Phosphoenolpyruvate carboxykinase (GTP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5105.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gtp_c" stoichiometry="1"/>          <speciesReference species="M_oaa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_gdp_c" stoichiometry="1"/>          <speciesReference species="M_pep_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PEPCKm" name="Phosphoenolpyruvate carboxykinase (GTP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5106.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gtp_m" stoichiometry="1"/>          <speciesReference species="M_oaa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_gdp_m" stoichiometry="1"/>          <speciesReference species="M_pep_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PERILLYLte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_perillyl_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_perillyl_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PETHCT" name="phosphoethanolamine cytidyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5833.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ctp_c" stoichiometry="1"/>          <speciesReference species="M_ethamp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdpea_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PETOHMm_hs" name="phosphatidylethanolamine N-methyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10400.2) or (10400.1) or (10400.3)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amet_m" stoichiometry="3"/>          <speciesReference species="M_pe_DASH_hs_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ahcys_m" stoichiometry="3"/>          <speciesReference species="M_h_m" stoichiometry="3"/>          <speciesReference species="M_pchol_DASH_hs_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PETOHMr_hs" name="phosphatidylethanolamine N-methyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10400.2) or (10400.1) or (10400.3)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amet_r" stoichiometry="3"/>          <speciesReference species="M_pe_DASH_hs_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ahcys_r" stoichiometry="3"/>          <speciesReference species="M_h_r" stoichiometry="3"/>          <speciesReference species="M_pchol_DASH_hs_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PE_HSter" name="phosphatidylethanolamine scramblase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pe_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pe_DASH_hs_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PE_HStm" name="phosphatidylethanolamine scramblase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pe_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pe_DASH_hs_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PFK" name="phosphofructokinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5214.1) or (5211.2) or (5214.1 and 5211.1) or (5214.1 and 5213.1) or (5213.1) or (5214.1 and 5211.2) or (5211.1) or (5211.1 and 5213.1) or (5213.1 and 5211.2)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_f6p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_fdp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PFK26" name=" 6-phosphofructo-2-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5210.1) or (5207.1) or (5209.1) or (5208.1)</p>            <p>SUBSYSTEM: Fructose and Mannose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_f6p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_f26bp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PGCD" name="phosphoglycerate dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (26227.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3pg_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3php_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PGI" name="glucose-6-phosphate isomerase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2821.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g6p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_f6p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PGK" name="phosphoglycerate kinase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5230.1) or (348477.1) or (5232.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3pg_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_13dpg_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PGL" name=" 6-phosphogluconolactonase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (25796.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_6pgl_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_6pgc_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PGM" name="phosphoglycerate mutase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (669.1) or (5223.1) or (5224.2) or (5224.1) or (669.2)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2pg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3pg_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PGMT" name="phosphoglucomutase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5236.1) or (55276.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g1p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_g6p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PHACCOAGLNAC" name="Phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Phenylalanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_phaccoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_pheacgln_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PHCDm" name="L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8659.1) or (8659.2)</p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_1p3h5c_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="2"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_e4hglu_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PHCHGSm" name="L-1-Pyrroline-3-hydroxy-5-carboxylate spontaneous conversion to L-4-Hydroxyglutamate semialdehyde, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_1p3h5c_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4hglusa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PHEACGLNt" name="PHEACGLN extracellular transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pheacgln_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pheacgln_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PHEMEtm" name="Heme transport to cytosol" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pheme_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pheme_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PHETHPTOX2" name="L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5053.1)</p>            <p>SUBSYSTEM: Tyr, Phe, Trp Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_phe_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_thbpt_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_thbpt4acam_c" stoichiometry="1"/>          <speciesReference species="M_tyr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PHEt4" name="L-phenylalanine transport in via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54407.1) or (84889.1) or (11254.1) or (6542.1) or (81539.1) or (6541.1) or (55089.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_phe_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_phe_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PHEtec" name="L-phenylalanine transport via diffusion (extracellular to cytosol)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (117247.1) or (124935.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_phe_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_phe_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PHYCBOXL" name="L-Phenylalanine carboxy-lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1644.1)</p>            <p>SUBSYSTEM: Phenylalanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_phe_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_peamn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI345P3P" name="phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5728.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pail345p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pail45p_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI345P3Pn" name="phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase, nuclear" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5728.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_n" stoichiometry="1"/>          <speciesReference species="M_pail345p_DASH_hs_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pail45p_DASH_hs_n" stoichiometry="1"/>          <speciesReference species="M_pi_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI345P5P" name="phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3633.1) or (27124.1) or (3635.1) or (3636.1) or (8871.1) or (56623.1) or (8867.2) or (27124.2) or (8867.1) or (3632.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pail345p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pail34p_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI34P5K" name="phosphatidylinositol 3,4-bisphosphate 5-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8394.1) or (23396.1) or (8395.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pail34p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail345p_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI35P3P" name="phosphatidylinositol-3,5-bisphosphate 3-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8897.1) or (8897.3) or (8897.2)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pail35p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pail5p_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI3P4K" name="phosphatidylinositol 3-phosphate 4-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55361.1) or (5297.1) or (8394.1) or (23396.1) or (8395.1) or (5298.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pail3p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail34p_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI3P5K" name="phosphatidylinositol 3-phosphate 5-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8394.1) or (23396.1) or (8395.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pail3p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail35p_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI3PP" name="phosphatidylinositol-3-phosphate 3-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8897.2) or (8897.3) or (8897.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pail3p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pail_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI45P3K" name="phosphatidylinositol 4,5-bisphosphate 3-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5290.1 and 8503.1) or (5293.1 and 5295.3) or (5290.1 and 5295.1) or (5295.2 and 5291.1) or (5293.1 and 5295.1) or (10870.1 and 5294.1) or (5293.1 and 5296.1) or (5291.1 and 5295.1) or (8503.1 and 5291.1) or (5296.1 and 5291.1) or (5291.1 and 5295.3) or (5290.1 and 5295.3) or (5295.2 and 5290.1) or (23533.1 and 5294.1) or (5293.1 and 8503.1) or (5295.2 and 5293.1) or (5296.1 and 5290.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pail45p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail345p_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI45P3Kn" name="phosphatidylinositol 4,5-bisphosphate 3-kinase, nuclear" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_pail45p_DASH_hs_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_h_n" stoichiometry="1"/>          <speciesReference species="M_pail345p_DASH_hs_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI45P5P" name="phosphatidylinositol-4,5-bisphosphate 5-phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8867.1) or (56623.1) or (4952.1) or (8871.1) or (8867.2) or (4952.2) or (3633.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pail45p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pail4p_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI45PLC" name="phosphatidylinositol 4,5-bisphosphate phospholipase C" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9651.1) or (5332.2) or (5333.1) or (113026.1) or (89869.1) or (84812.1) or (5334.1) or (5331.1) or (5332.1) or (23007.1) or (23236.2) or (257068.1) or (5335.1) or (5335.2) or (23236.1) or (51196.1) or (5330.1) or (5336.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pail45p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mi145p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI4P3K" name="phosphatidylinositol 4-phosphate 3-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5290.1 and 5295.1) or (5286.1) or (5291.1 and 5295.3) or (5293.1 and 5295.3) or (5295.2 and 5293.1) or (5296.1 and 5291.1) or (5295.2 and 5291.1) or (5296.1 and 5290.1) or (23533.1 and 5294.1) or (5293.1 and 5296.1) or (5288.1) or (5295.2 and 5290.1) or (5293.1 and 5295.1) or (5290.1 and 8503.1) or (5291.1 and 5295.1) or (5287.1) or (5293.1 and 8503.1) or (8503.1 and 5291.1) or (5290.1 and 5295.3) or (10870.1 and 5294.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pail4p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail34p_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI4P5K" name="phosphatidylinositol 4-phosphate 5-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (200576.2) or (8396.1) or (200576.3) or (79837.1) or (8394.1) or (23396.1) or (8395.1) or (8396.2) or (5305.1) or (200576.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pail4p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail45p_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI4PLC" name="phosphatidylinositol 4-phosphate phospholipase C" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23236.2) or (5336.1) or (5334.1) or (89869.1) or (5330.1) or (84812.1) or (5335.2) or (23007.1) or (51196.1) or (113026.1) or (5332.2) or (9651.1) or (5331.1) or (5335.1) or (5332.1) or (257068.1) or (23236.1) or (5333.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pail4p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mi14p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI4PLCn" name="phosphatidylinositol 4-phosphate phospholipase C, nucleus" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23236.2) or (23236.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_n" stoichiometry="1"/>          <speciesReference species="M_pail4p_DASH_hs_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dag_DASH_hs_n" stoichiometry="1"/>          <speciesReference species="M_h_n" stoichiometry="1"/>          <speciesReference species="M_mi14p_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI5P3K" name="phosphatidylinositol-5-phosphate 3-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5295.2 and 5291.1) or (23533.1 and 5294.1) or (5295.2 and 5290.1) or (5293.1 and 5295.3) or (5287.1) or (5286.1) or (5293.1 and 5296.1) or (5295.2 and 5293.1) or (5296.1 and 5291.1) or (5290.1 and 5295.1) or (5288.1) or (5290.1 and 8503.1) or (5291.1 and 5295.3) or (10870.1 and 5294.1) or (8503.1 and 5291.1) or (5293.1 and 5295.1) or (5296.1 and 5290.1) or (5289.1) or (5293.1 and 8503.1) or (5291.1 and 5295.1) or (5290.1 and 5295.3)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pail5p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail35p_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PI5P4K" name="phosphatidylinositol-5-phosphate 4-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5297.1) or (55361.1) or (5298.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pail5p_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail45p_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PIK3" name="phosphatidylinositol 3-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5295.2 and 5290.1) or (5293.1 and 5295.1) or (5286.1) or (5295.2 and 5291.1) or (5293.1 and 5295.3) or (5295.2 and 5293.1) or (5291.1 and 5295.3) or (5291.1 and 5295.1) or (5290.1 and 5295.1) or (23533.1 and 5294.1) or (5293.1 and 5296.1) or (5288.1) or (5290.1 and 5295.3) or (8503.1 and 5291.1) or (5296.1 and 5290.1) or (5290.1 and 8503.1) or (5287.1) or (5293.1 and 8503.1) or (5296.1 and 5291.1) or (5289.1) or (10870.1 and 5294.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pail_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail3p_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PIK4" name="phosphatidylinositol 4-kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5298.1) or (55361.1) or (5297.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pail_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pail4p_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PIPLC" name="phosphatidylinositol phospholipase C" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23236.2) or (5336.1) or (5334.1) or (89869.1) or (5330.1) or (84812.1) or (5335.2) or (23007.1) or (51196.1) or (113026.1) or (5332.2) or (9651.1) or (5331.1) or (5335.1) or (5332.1) or (257068.1) or (23236.1) or (5333.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pail_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mi1p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PIPLCn" name="phosphatidylinositol phospholipase C, nucleus" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23236.2) or (23236.1)</p>            <p>SUBSYSTEM: Inositol Phosphate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_n" stoichiometry="1"/>          <speciesReference species="M_pail_DASH_hs_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dag_DASH_hs_n" stoichiometry="1"/>          <speciesReference species="M_h_n" stoichiometry="1"/>          <speciesReference species="M_mi1p_DASH_DASH_DASH_D_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PIt2m" name="phosphate transporter, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5250.4) or (5250.1) or (5250.3) or (5250.2)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PIt7ir" name="phosphate transport in/out via three Na+ symporter (irreversible)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10050.1) or (10786.1) or (10246.1) or (6568.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="3"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="3"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PIt8" name="phosphate transport in/out via Na+ symporter" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6574.1) or (6575.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1.5"/>          <speciesReference species="M_pi_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1.5"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PIter" name="phosphate transport, endoplasmic reticulum" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2544.1)</p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pi_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PItn" name="phosphate transport, nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Nuclear</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pi_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PItx" name="Phosphate transporter, peroxisome" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PLA2_2" name="phospholipase A2" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8398.1) or (5320.1) or (8398.2)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pchol_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal2_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lpchol_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PLA2_2e" name="phospholipase A2" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5322.1) or (5319.1) or (81579.1) or (64600.1) or (26279.1) or (5320.1) or (8399.1) or (30814.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_e" stoichiometry="1"/>          <speciesReference species="M_pchol_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal2_e" stoichiometry="1"/>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_lpchol_DASH_hs_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PMEVKx" name="phosphomevalonate kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10654.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5pmev_x" stoichiometry="1"/>          <speciesReference species="M_atp_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5dpmev_x" stoichiometry="1"/>          <speciesReference species="M_adp_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PNP" name="purine-nucleoside phosphorylase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4860.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_rnam_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_ncam_c" stoichiometry="1"/>          <speciesReference species="M_r1p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PNTEH" name="Hydrolase Class ( RXN R02973)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8876.1) and (8875.2) and (55350.3) or (8876.1) and (8875.2) and (55350.2) or (8876.1) and (8875.1) and (55350.1) or (8876.1) and (55350.2) and (8875.1) or (8875.2) and (8876.1) and (55350.1) or (8876.1) and (55350.3) and (8875.1)</p>            <p>SUBSYSTEM: CoA Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_ptth_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cysam_c" stoichiometry="1"/>          <speciesReference species="M_pnto_DASH_DASH_DASH_R_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PNTK" name="pantothenate kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (79646.1) or (80025.2) or (53354.1) or (53354.3) or (80025.1) or (53354.2) or (80025.3) or (80025.4) or (55229.1)</p>            <p>SUBSYSTEM: CoA Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pnto_DASH_DASH_DASH_R_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4ppan_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPA" name="inorganic diphosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5464.1)</p>            <p>SUBSYSTEM: Oxidative Phosphorylation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPAP" name="phosphatidic acid phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8612.1) or (8611.1) or (8613.1) or (8611.2)</p>            <p>SUBSYSTEM: Triacylglycerol Synthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pa_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPAer" name="inorganic diphosphatase, endoplasmic reticulum" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2538.1) or (92579.1) or (57818.1)</p>            <p>SUBSYSTEM: Miscellaneous</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_ppi_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_pi_r" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPAm" name="inorganic diphosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (27068.4) or (27068.1) or (27068.3) or (27068.2)</p>            <p>SUBSYSTEM: Oxidative Phosphorylation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_ppi_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPAn" name="inorganic diphosphatase, nuclear" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Miscellaneous</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_n" stoichiometry="1"/>          <speciesReference species="M_ppi_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_n" stoichiometry="1"/>          <speciesReference species="M_pi_n" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPAt" name="Propionate transport, diffusion" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ppa_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ppa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPBNGS" name="porphobilinogen synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (210.1) or (210.2)</p>            <p>SUBSYSTEM: Heme Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5aop_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="2"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_ppbng_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPCDC" name="phosphopantothenoylcysteine decarboxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (60490.1)</p>            <p>SUBSYSTEM: CoA Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4ppcys_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_pan4p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPCOACm" name="Propionyl-CoA carboxylase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5096.1 and 5095.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_hco3_m" stoichiometry="1"/>          <speciesReference species="M_ppcoa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_mmcoa_DASH_DASH_DASH_S_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPD2CSPp" name="PPD2CSPp" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_6a2ohxnt_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_1pipdn2c_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPDOx" name="Propane-1,2-diol:NAD+ 1-oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8574.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lald_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_12ppd_DASH_DASH_DASH_R_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPDOy" name="Propane-1,2-diol:NADP+ 1-oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8574.1) or (231.1) or (10327.2) or (10327.1)</p>            <p>SUBSYSTEM: Pyruvate Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_lald_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_12ppd_DASH_DASH_DASH_R_c" stoichiometry="1"/>          <speciesReference species="M_nadp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPItx" name="Diphosphate transporter, peroxisome" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ppi_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPM" name="phosphopentomutase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5236.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_r1p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_r5p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPNCL3" name="phosphopantothenate-cysteine ligase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (79717.1)</p>            <p>SUBSYSTEM: CoA Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_4ppan_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4ppcys_c" stoichiometry="1"/>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPPG9tm" name="protoporphyrinogen IX mitochondrial transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Heme Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pppg9_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pppg9_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PPPGOm" name="protoporphyrinogen oxidase, mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5498.1)</p>            <p>SUBSYSTEM: Heme Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2_m" stoichiometry="3"/>          <speciesReference species="M_pppg9_m" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_m" stoichiometry="6"/>          <speciesReference species="M_ppp9_m" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PRAGSr" name="phosphoribosylglycinamide synthase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2618.1) or (2618.2)</p>            <p>SUBSYSTEM: IMP Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_gly_c" stoichiometry="1"/>          <speciesReference species="M_pram_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_gar_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PRAIS" name="phosphoribosylaminoimidazole synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2618.1) or (2618.2)</p>            <p>SUBSYSTEM: IMP Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_fpram_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_air_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PRASCS" name="phosphoribosylaminoimidazolesuccinocarboxamide synthase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10606.1)</p>            <p>SUBSYSTEM: IMP Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5aizc_c" stoichiometry="1"/>          <speciesReference species="M_asp_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_atp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_25aics_c" stoichiometry="1"/>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PRFGS" name="phosphoribosylformylglycinamidine synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5198.1)</p>            <p>SUBSYSTEM: IMP Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_fgam_c" stoichiometry="1"/>          <speciesReference species="M_gln_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_fpram_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PRGNLONESULT" name="steroid sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6822.1) or (6820.2)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_paps_c" stoichiometry="1"/>          <speciesReference species="M_prgnlone_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>          <speciesReference species="M_prgnlones_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PRISTCOAtx" name="pristcoa peroxisomal transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pristcoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pristcoa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PRISTtx" name="prist peroxisomal transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_prist_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_prist_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PRO1x" name="proline oxidase (L-proline, NAD)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (58510.1)</p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_pro_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_1pyr5c_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PROD2" name="Proline dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (58510.1)</p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_c" stoichiometry="1"/>          <speciesReference species="M_pro_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_1pyr5c_c" stoichiometry="1"/>          <speciesReference species="M_fadh2_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PROD2m" name="Proline dehydrogenase (m)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5625.1)</p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_pro_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_1pyr5c_m" stoichiometry="1"/>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PROSTGE2t2" name="prostaglandin uniport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6582.2) or (6582.1) or (6580.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_prostge2_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_prostge2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PROSTGF2t" name="prostaglandin uniport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6582.2) or (6582.1) or (6580.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_prostgf2_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_prostgf2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PROt4" name="Na+/Proline-L symporter" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55089.1) or (81539.1) or (54407.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_pro_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_pro_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PROtm" name="L-proline transport, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pro_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pro_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PRPPS" name="phosphoribosylpyrophosphate synthetase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (221823.2) or (5631.1) or (221823.1) or (5634.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_r5p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_prpp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PSDm_hs" name="Phosphatidylserine decarboxylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23761.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_ps_DASH_hs_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_m" stoichiometry="1"/>          <speciesReference species="M_pe_DASH_hs_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PSERT" name="phosphoserine transaminase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (29968.1) or (29968.2)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_3php_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_akg_c" stoichiometry="1"/>          <speciesReference species="M_pser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PSFLIP" name="phosphatidylserine flippase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10396.1) or (57194.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_ps_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_ps_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PSFLIPm" name="phosphatidylserine flippase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10396.1) or (57194.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_ps_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_ps_DASH_hs_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PSP_L" name="phosphoserine phosphatase (L-serine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8781.1) or (5723.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PSSA1_hs" name="Phosphatidylserine synthase homo sapiens" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9791.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pchol_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chol_c" stoichiometry="1"/>          <speciesReference species="M_ps_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PSSA2_hs" name="Phosphatidylserine synthase homo sapiens" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (81490.1)</p>            <p>SUBSYSTEM: Glycerophospholipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pe_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_etha_c" stoichiometry="1"/>          <speciesReference species="M_ps_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PTDCACRNCPT1" name="carnitine fatty-acyl transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.4) or (1375.3) or (1374.1) or (126129.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_ptdcacoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_ptdcacrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PTDCACRNCPT2" name="pentadecanoate transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_ptdcacrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_ptdcacoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PTDCACRNt" name="pentadecanoate transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ptdcacrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ptdcacrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PTDCAt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ptdca_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ptdca_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PTE3x" name="peroxisomal acyl-CoA thioesterase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10965.1)</p>            <p>SUBSYSTEM: Fatty Acid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_pristcoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_prist_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PUNP1" name="purine-nucleoside phosphorylase (Adenosine)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4860.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adn_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ade_c" stoichiometry="1"/>          <speciesReference species="M_r1p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PUNP2" name="purine-nucleoside phosphorylase (Deoxyadenosine)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4860.1)</p>            <p>SUBSYSTEM: Purine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dad_DASH_DASH_DASH_2_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2dr1p_c" stoichiometry="1"/>          <speciesReference species="M_ade_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PUNP3" name="purine-nucleoside phosphorylase (Guanosine)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4860.1)</p>            <p>SUBSYSTEM: Purine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gsn_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gua_c" stoichiometry="1"/>          <speciesReference species="M_r1p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PUNP4" name="purine-nucleoside phosphorylase (Deoxyguanosine)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4860.1)</p>            <p>SUBSYSTEM: Purine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dgsn_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2dr1p_c" stoichiometry="1"/>          <speciesReference species="M_gua_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PUNP5" name="purine-nucleoside phosphorylase (Inosine)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4860.1)</p>            <p>SUBSYSTEM: Purine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ins_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hxan_c" stoichiometry="1"/>          <speciesReference species="M_r1p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PUNP6" name="purine-nucleoside phosphorylase (Deoxyinosine)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4860.1)</p>            <p>SUBSYSTEM: Purine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_din_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2dr1p_c" stoichiometry="1"/>          <speciesReference species="M_hxan_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PUNP7" name="purine-nucleoside phosphorylase (Xanthosine)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4860.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_xtsn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_r1p_c" stoichiometry="1"/>          <speciesReference species="M_xan_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PVD3" name="Previtamin D3 formation" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Vitamin D</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_7dhchsterol_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pd3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYAM5POr" name="pyridoxamine 5&apos;-phosphate oxidase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55163.1)</p>            <p>SUBSYSTEM: Vitamin B6 Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_pyam5p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>          <speciesReference species="M_pydx5p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYDAMK" name="pyridoxamine kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8566.1)</p>            <p>SUBSYSTEM: Vitamin B6 Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pydam_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pyam5p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYDAMtr" name="pyridoxamine transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pydam_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pydam_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYDXDH" name="pyridoxal dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (316.1)</p>            <p>SUBSYSTEM: Vitamin B6 Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_pydx_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4pyrdx_c" stoichiometry="1"/>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYDXK" name="pyridoxal kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8566.1)</p>            <p>SUBSYSTEM: Vitamin B6 Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pydx_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pydx5p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYDXNK" name="pyridoxine kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8566.1)</p>            <p>SUBSYSTEM: Vitamin B6 Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pydxn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pdx5p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYDXNtr" name="pyridoxine transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pydxn_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pydxn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYDXPP" name="Pyridoxal 5-phosphate phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (57026.1)</p>            <p>SUBSYSTEM: Vitamin B6 Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_pydx5p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_pydx_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYK" name="pyruvate kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5315.2) or (5313.2) or (5315.3) or (5313.1) or (113452.1) or (5315.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pep_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYRt2m" name="pyruvate mitochondrial transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6566.1)</p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_pyr_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYRt2p" name="pyruvate peroxisomal transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6566.1) or (9194.1)</p>            <p>SUBSYSTEM: D-alanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_pyr_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_PYRt2r" name="pyruvate reversible transport via proton symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9123.1) or (9194.1) or (6566.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_pyr_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pyr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_QUILSYN" name="Quinolinate Synthase (Eukaryotic)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cmusa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_quln_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RAI3" name=" 13-cis-retinoic acid isomerase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2944.1) or (2944.2)</p>            <p>SUBSYSTEM: Vitamin A Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_retn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RBFK" name="riboflavin kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55312.1)</p>            <p>SUBSYSTEM: Riboflavin Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_ribflv_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_fmn_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RBK" name="ribokinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (64080.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_rib_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_r5p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RDH1" name="retinol dehydrogenase (all-trans)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5959.1) or (8608.1)</p>            <p>SUBSYSTEM: Vitamin A Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_retinol_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_retinal_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RDH1a" name="retinol dehydrogenase (all-trans,NADPH)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (157506.1) or (112724.1) or (145226.1) or (51109.1) or (195814.1) or (57665.1) or (50700.1)</p>            <p>SUBSYSTEM: Vitamin A Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_retinol_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_retinal_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RDH2" name="retinol dehydrogenase (9-cis,NADH)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5959.1)</p>            <p>SUBSYSTEM: Vitamin A Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_retinol_DASH_DASH_DASH_9_DASH_DASH_DASH_cis_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_retinal_DASH_DASH_DASH_cis_DASH_DASH_DASH_9_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RDH2a" name="retinol dehydrogenase (9-cis,NADPH)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (195814.1) or (112724.1) or (145226.1) or (51109.1) or (57665.1) or (50700.1)</p>            <p>SUBSYSTEM: Vitamin A Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_retinol_DASH_DASH_DASH_9_DASH_DASH_DASH_cis_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_retinal_DASH_DASH_DASH_cis_DASH_DASH_DASH_9_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RDH3" name="retinol dehydrogenase (11-cis,NADH)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5959.1)</p>            <p>SUBSYSTEM: Vitamin A Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_retinol_DASH_DASH_DASH_cis_DASH_DASH_DASH_11_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_retinal_DASH_DASH_DASH_11_DASH_DASH_DASH_cis_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RDH3a" name="retinol dehydrogenase (11-cis,NADPH)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (112724.1) or (145226.1) or (51109.1) or (57665.1) or (195814.1)</p>            <p>SUBSYSTEM: Vitamin A Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_retinol_DASH_DASH_DASH_cis_DASH_DASH_DASH_11_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_retinal_DASH_DASH_DASH_11_DASH_DASH_DASH_cis_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RETNGLCt" name="retinoyl glucuronide efflux" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_retnglc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_retnglc_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RETNGLCt2" name="retinoyl glucuronide efflux (13-cis)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retnglc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retnglc_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RETNGLCt2r" name="retinoyl glucuronide efflux (13-cis) from ER" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retnglc_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retnglc_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RETNGLCtr" name="retinoyl glucuronide efflux from ER" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_retnglc_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_retnglc_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RETNt" name="retinoic acid transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_retn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_retn_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RETNtr" name="retinoic acid transport in ER" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_retn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_retn_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RETNtr2" name="retinoic acid transport in ER (13-cis)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retn_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RIBt2" name="ribose transport in via proton symporter" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_rib_DASH_DASH_DASH_D_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_rib_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RNDR1" name="ribonucleoside-diphosphate reductase (ADP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6240.1 and 6241.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_trdrd_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dadp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_trdox_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RNDR2" name="ribonucleoside-diphosphate reductase (GDP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6240.1 and 6241.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gdp_c" stoichiometry="1"/>          <speciesReference species="M_trdrd_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dgdp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_trdox_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RNDR4" name="ribonucleoside-diphosphate reductase (UDP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6240.1 and 6241.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_trdrd_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dudp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_trdox_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RNMK" name="ribosylnicotinamide kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54981.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_rnam_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nmn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RPE" name="ribulose 5-phosphate 3-epimerase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6120.1) or (6120.2)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ru5p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xu5p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RPI" name="ribose-5-phosphate isomerase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (22934.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_r5p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ru5p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RTOTAL2CRNCPT1" name="carnitine fatty-acyl transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.4) or (1375.3) or (1374.1) or (126129.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal2coa_c" stoichiometry="1"/>          <speciesReference species="M_crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal2crn_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RTOTAL2CRNCPT2" name="R group transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal2crn_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal2coa_m" stoichiometry="1"/>          <speciesReference species="M_crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RTOTAL2CRNt" name="R group transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal2crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal2crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RTOTAL3CRNCPT1" name="carnitine fatty-acyl transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.4) or (1375.1) or (1374.1) or (126129.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal3coa_c" stoichiometry="1"/>          <speciesReference species="M_crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal3crn_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RTOTAL3CRNCPT2" name="R group transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal3crn_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal3coa_m" stoichiometry="1"/>          <speciesReference species="M_crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RTOTAL3CRNt" name="R group transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal3crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal3crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RTOTALCRNCPT1" name="carnitine fatty-acyl transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.4) or (1375.3) or (1374.1) or (126129.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotalcoa_c" stoichiometry="1"/>          <speciesReference species="M_crn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotalcrn_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RTOTALCRNCPT2" name="R group transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotalcrn_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotalcoa_m" stoichiometry="1"/>          <speciesReference species="M_crn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_RTOTALCRNt" name="R group transport into the mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotalcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotalcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_Rtotaltl" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Rtotal_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Rtotal_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_S2L2N2M2MASNtly" name="s2l2n2m2masn transport, extracellular to lysosome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_s2l2n2m2masn_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_s2l2n2m2masn_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SACCD3m" name="saccharopine dehydrogenase (NADP, L-lysine forming), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10157.1)</p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_lys_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>          <speciesReference species="M_saccrp_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SACCD4m" name="saccharopine dehydrogenase (NAD, L-glutamate forming), mitochondrial" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10157.1)</p>            <p>SUBSYSTEM: Lysine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>          <speciesReference species="M_saccrp_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_L2aadp6sa_m" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SADT" name="sulfate adenylyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9060.1) or (9061.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_so4_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_aps_c" stoichiometry="1"/>          <speciesReference species="M_ppi_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SAMHISTA" name="S-Adenosyl-L-methionine:histamine N-tele-methyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3176.1)</p>            <p>SUBSYSTEM: Histidine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_amet_c" stoichiometry="1"/>          <speciesReference species="M_hista_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ahcys_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_mhista_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SARCStm" name="Sarcosine transport (mitochondrial)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_sarcs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_sarcs_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SARDHm" name="Sarcosine dehydrogenase (m)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1757.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_sarcs_m" stoichiometry="1"/>          <speciesReference species="M_thf_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>          <speciesReference species="M_gly_m" stoichiometry="1"/>          <speciesReference species="M_mlthf_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SBPP1er" name="sphingoid base-phosphate phosphatase (sphinganine 1-phosphatase), endoplasmic reticulum" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (81537.1)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_sph1p_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_r" stoichiometry="1"/>          <speciesReference species="M_sphgn_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SBPP3er" name="sphingoid base-phosphate phosphatase (sphinganine 1-phosphatase), endoplasmic reticulum" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (81537.1)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_sphs1p_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_r" stoichiometry="1"/>          <speciesReference species="M_sphings_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SBTD_D2" name="D-sorbitol dehydrogenase (D-fructose producing)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6652.1)</p>            <p>SUBSYSTEM: Fructose and Mannose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_sbt_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fru_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SBTR" name="D-sorbitol reductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8574.1) or (10327.1) or (231.1) or (10327.2)</p>            <p>SUBSYSTEM: Fructose and Mannose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_glc_DASH_DASH_DASH_D_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_sbt_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SCP2x" name="peroxisomal thiolase 2" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6342.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_dhocholoylcoa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dgcholcoa_x" stoichiometry="1"/>          <speciesReference species="M_ppcoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SCP3x" name="peroxisomal thiolase 2" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6342.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_dhcholestancoa_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcholcoa_x" stoichiometry="1"/>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_ppcoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SCPx" name="peroxisomal thiolase 2" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6342.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cholcoaone_x" stoichiometry="1"/>          <speciesReference species="M_coa_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cholcoa_x" stoichiometry="1"/>          <speciesReference species="M_ppcoa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SERALANaEx" name="L-alanine/L-serine Na-dependent exchange (Ser-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SERCYSNaEx" name="L-serine/L-cysteine Na-dependent exchange (Ser-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cys_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SERHL" name="L-Serine hydro-lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10993.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2amac_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SERPT" name="serine C-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10558.1 and 9517.1)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pmtcoa_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3dsphgn_c" stoichiometry="1"/>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_coa_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SERTHRNaEx" name="L-serine/L-threonine Na-dependent exchange (Ser-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SERt4" name="L-serine via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (81539.1) or (11254.1) or (54407.1) or (55089.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SERtp" name="L-serine transport, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ser_DASH_DASH_DASH_L_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SFGTH" name="S-Formylglutathione hydralase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2098.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_Sfglutth_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_for_c" stoichiometry="1"/>          <speciesReference species="M_gthrd_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SGPL12r" name="Sphingosine-1-phosphate lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8879.1)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_sphs1p_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ethamp_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_hdca_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SIAASEly" name="sialidase, lysosomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1)</p>            <p>SUBSYSTEM: N-Glycan Degradation</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="2"/>          <speciesReference species="M_s2l2n2m2mn_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acnam_l" stoichiometry="2"/>          <speciesReference species="M_l2n2m2mn_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SLCBK1" name="sphingolipid long chain base kinase (sphinganine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (56848.1)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_sphgn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_sph1p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SLDt" name="L-sulfolactate transport (cytosol to extracellular)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_sl_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_sl_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SLDx" name="L-sulfolactate dehydrogenase (NAD+)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4190.1) or (130752.1)</p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_sl_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3spyr_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SMPD3l" name="sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (55512.1) or (55512.2)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_l" stoichiometry="1"/>          <speciesReference species="M_sphmyln_DASH_hs_l" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cholp_l" stoichiometry="1"/>          <speciesReference species="M_crm_DASH_hs_l" stoichiometry="1"/>          <speciesReference species="M_h_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SMS" name="Sphingomyelin synthase (homo sapiens)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (259230.1)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crm_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_pchol_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dag_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_sphmyln_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SO4HCOtex" name="sulfate transport via bicarbonate countertransport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (115111.1) or (115019.2) or (1836.1) or (115111.2) or (116369.2) or (284129.1) or (10861.2) or (116369.1) or (10861.1) or (10861.3) or (115019.1) or (1811.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hco3_c" stoichiometry="2"/>          <speciesReference species="M_so4_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hco3_e" stoichiometry="2"/>          <speciesReference species="M_so4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SO4OXAtex2" name="sulfate transport via oxalate countertransport (2:1)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (65010.1) or (65010.3) or (65010.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_oxa_c" stoichiometry="1"/>          <speciesReference species="M_so4_e" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_oxa_e" stoichiometry="1"/>          <speciesReference species="M_so4_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SO4t4_3" name="sulfate transport via sodium symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6561.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="3"/>          <speciesReference species="M_so4_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="3"/>          <speciesReference species="M_so4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SOAT11" name="sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6646.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_R1coa_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_chsterol_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_xolest_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SOAT12" name="sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6646.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_R2coa_DASH_hs_c" stoichiometry="1"/>          <speciesReference species="M_chsterol_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_xolest_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPH1Ptr" name="sph1p intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_sph1p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_sph1p_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPHGNtr" name="sphinganine intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_sphgn_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_sphgn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPHINGStl" name="sphingosine intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_sphings_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_sphings_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPHINGStr" name="sphingosine intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_sphings_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_sphings_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPHK21c" name="sphingosine kinase 2" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (56848.1)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_sphings_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_sphs1p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPHMYLNtl" name="sphingomyelin intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_sphmyln_DASH_hs_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_sphmyln_DASH_hs_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPHS1Ptr" name="sphingosine-1-phosphate transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_sphs1p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_sphs1p_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPMDOX" name="Spermidine:(acceptor) oxidoreductase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: beta-Alanine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_spmd_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_13dampp_c" stoichiometry="1"/>          <speciesReference species="M_4abutn_c" stoichiometry="1"/>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPMS" name="spermidine synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6723.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ametam_c" stoichiometry="1"/>          <speciesReference species="M_ptrc_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5mta_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_spmd_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPODM" name="superoxide dismutase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6647.1)</p>            <p>SUBSYSTEM: ROS Detoxification</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_o2s_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPODMm" name="superoxide dismutase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6648.1)</p>            <p>SUBSYSTEM: ROS Detoxification</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_o2s_m" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_m" stoichiometry="1"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPODMn" name="superoxide dismutase, nuclear" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6647.1)</p>            <p>SUBSYSTEM: ROS Detoxification</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_n" stoichiometry="2"/>          <speciesReference species="M_o2s_n" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_n" stoichiometry="1"/>          <speciesReference species="M_o2_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPODMx" name="superoxide dismutase, peroxisome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6647.1)</p>            <p>SUBSYSTEM: ROS Detoxification</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_x" stoichiometry="2"/>          <speciesReference species="M_o2s_x" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPRMS" name="spermine synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6611.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ametam_c" stoichiometry="1"/>          <speciesReference species="M_spmd_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5mta_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_sprm_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SPTix" name="serine-pyruvate aminotransferase (irreversible), peroxisomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (189.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pyr_x" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_L_x" stoichiometry="1"/>          <speciesReference species="M_hpyr_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SQLEr" name="Squalene epoxidase, endoplasmic reticular (NADP)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6713.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>          <speciesReference species="M_o2_r" stoichiometry="1"/>          <speciesReference species="M_sql_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Ssq23epx_r" stoichiometry="1"/>          <speciesReference species="M_h2o_r" stoichiometry="1"/>          <speciesReference species="M_nadp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SQLSr" name="Squalene synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2222.1)</p>            <p>SUBSYSTEM: Cholesterol Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_frdp_r" stoichiometry="2"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_nadph_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_r" stoichiometry="1"/>          <speciesReference species="M_ppi_r" stoichiometry="2"/>          <speciesReference species="M_sql_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SRTNtu" name="Serotonin uniport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6580.1) or (6582.2) or (6582.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_srtn_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_srtn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SSALxm" name="succinate-semialdehyde dehydrogenase (NAD) reversible (mitochondrial)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7915.1) or (7915.2)</p>            <p>SUBSYSTEM: Glutamate metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>          <speciesReference species="M_sucsal_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="2"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_succ_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_STRDNCCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_strdnccoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_strdnccrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_STRDNCCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_strdnccrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_strdnccoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_STRDNCCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_strdnccrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_strdnccrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_STRDNCt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_strdnc_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_strdnc_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_STS1" name="Steryl-sulfatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (412.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dheas_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhea_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_so4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_STS2" name="Steryl-sulfatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (412.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estrones_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estrone_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_so4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_STS3" name="Steryl-sulfatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (412.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_chsterols_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_chsterol_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_so4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_STS4" name="Steryl-sulfatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (412.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_prgnlones_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_prgnlone_c" stoichiometry="1"/>          <speciesReference species="M_so4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SUCD1m" name="succinate dehydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6389.1 and 6392.1 and 6391.1 and 6390.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_fad_m" stoichiometry="1"/>          <speciesReference species="M_succ_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_fadh2_m" stoichiometry="1"/>          <speciesReference species="M_fum_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SUCOAS1m" name="Succinate--CoA ligase (GDP-forming)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8802.1 and 8801.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_gtp_m" stoichiometry="1"/>          <speciesReference species="M_succ_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gdp_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>          <speciesReference species="M_succoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SUCOASm" name="Succinate--CoA ligase (ADP-forming)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8802.1 and 8803.1)</p>            <p>SUBSYSTEM: Citric Acid Cycle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_succ_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_pi_m" stoichiometry="1"/>          <speciesReference species="M_succoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_SULFOX" name="sulfite oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6821.1)</p>            <p>SUBSYSTEM: Cysteine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ficytC_m" stoichiometry="2"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_so3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_focytC_m" stoichiometry="2"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_so4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TAGAT_Dt" name="D-tagatose uptake via diffusion" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tagat_DASH_DASH_DASH_D_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tagat_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TALA" name="transaldolase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6888.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_g3p_c" stoichiometry="1"/>          <speciesReference species="M_s7p_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_e4p_c" stoichiometry="1"/>          <speciesReference species="M_f6p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TAURtcx" name="taurine transport (sodium symport) (cytosol to peroxisome)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6533.1)</p>            <p>SUBSYSTEM: Taurine and hypotaurine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_taur_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_x" stoichiometry="1"/>          <speciesReference species="M_taur_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TAXOLte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_taxol_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_taxol_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TCHOLAt" name="taurocholate transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (28231.1) or (6579.1) or (28234.1) or (10599.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hco3_c" stoichiometry="1"/>          <speciesReference species="M_tchola_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hco3_e" stoichiometry="1"/>          <speciesReference species="M_tchola_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TCHOLAt2" name="taurocholate transport via sodium cotransport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6554.1) or (6555.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="2"/>          <speciesReference species="M_tchola_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="2"/>          <speciesReference species="M_tchola_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TCHOLAt3" name="ABC bile acid transporter" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8714.3) or (8647.1) or (8714.2) or (8714.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_tchola_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_tchola_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TCHOLAtx" name="bile acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tchola_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tchola_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TCYNTt" name="Thiocyanate transport via diffusion (cytosol to extracellular)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tcynt_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tcynt_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TCYNTtm" name="Thiocyanate transport via diffusion (mitochondrial)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tcynt_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tcynt_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TDCHOLAte" name="bile acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tdchola_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tdchola_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TDCHOLAtx" name="bile acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tdchola_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tdchola_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TETHEX3COAtx" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tethex3coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tethex3coa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TETHEX3t" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tethex3_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tethex3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TETPENT3COAtx" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tetpent3coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tetpent3coa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TETPENT3t" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tetpent3_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tetpent3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TETPENT6COAtx" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tetpent6coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tetpent6coa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TETPENT6t" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tetpent6_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tetpent6_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TETTET6COAtx" name="fatty acid intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tettet6coa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tettet6coa_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TETTET6t" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tettet6_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tettet6_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THBPT4ACAMDASE" name="Tetrahydrobiopterin-4a-carbinolamine dehydratase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5092.1) or (5092.2)</p>            <p>SUBSYSTEM: Tetrahydrobiopterin</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thbpt4acam_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhbpt_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THCHOLSTOICtm" name="lipid, flip-flop intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thcholstoic_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_thcholstoic_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THD1m" name="NAD(P) transhydrogenase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23530.2) or (23530.1)</p>            <p>SUBSYSTEM: NAD Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nad_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THFt2" name="tetrahydrofolate transport via anion exchange" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6573.1) or (6573.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_oh1_c" stoichiometry="1"/>          <speciesReference species="M_thf_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_oh1_e" stoichiometry="1"/>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THFtl" name=" 5,6,7,8-Tetrahydrofolate transport, diffusion, lysosomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Lysosomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_thf_l" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THFtm" name=" 5,6,7,8-Tetrahydrofolate transport, diffusion, mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_thf_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THMDt4" name="thymidine transport in via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9154.1) or (9154.2) or (64078.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_thymd_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_thymd_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THMMPt4" name="Thiamine monophosphate transport in via anion antiport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6573.1) or (6573.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_oh1_c" stoichiometry="1"/>          <speciesReference species="M_thmmp_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_oh1_e" stoichiometry="1"/>          <speciesReference species="M_thmmp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THMP" name="thiamin phosphatase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Thiamine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_thmmp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_thm_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THMTPt" name="Thiamine triphosphate transport in via anion antiport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6573.1) or (6573.2)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_oh1_e" stoichiometry="3"/>          <speciesReference species="M_thmtp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_oh1_c" stoichiometry="3"/>          <speciesReference species="M_thmtp_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THMt3" name="Thiamine transport in via proton  antiport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (80704.1) or (10560.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_thm_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_e" stoichiometry="1"/>          <speciesReference species="M_thm_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THP2Ctp" name=" 2,3,4,5-Tetrahydropyridine-2-carboxylate transport, peroxisomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thp2c_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_thp2c_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THRALANaEx" name="L-alanine/L-threonine Na-dependent exchange (Thr-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ala_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THRCYSNaEx" name="L-cysteine/L-threonine Na-dependent exchange (Thr-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cys_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cys_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THRD_L" name="L-threonine deaminase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10993.1)</p>            <p>SUBSYSTEM: Glycine, Serine, and Threonine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2obut_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THRSERNaEx" name="L-serine/L-threonine Na-dependent exchange (Thr-L in)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6509.1) or (6510.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_c" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_ser_DASH_DASH_DASH_L_e" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THRt4" name="L-threonine  via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11254.1) or (81539.1) or (54407.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_thr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THYMDt1" name="thymd transport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3177.1) or (2030.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thymd_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_thymd_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THYOXt" name="T4 transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (53919.1) or (6579.1) or (28231.1) or (10599.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hco3_c" stoichiometry="1"/>          <speciesReference species="M_thyox_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hco3_e" stoichiometry="1"/>          <speciesReference species="M_thyox_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_THYOXt2" name="T4 transport via facilitated diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6567.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_thyox_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_thyox_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TKT1" name="transketolase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7086.1) or (84076.1) or (8277.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_r5p_c" stoichiometry="1"/>          <speciesReference species="M_xu5p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_g3p_c" stoichiometry="1"/>          <speciesReference species="M_s7p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TKT2" name="transketolase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7086.1) or (84076.1) or (8277.1)</p>            <p>SUBSYSTEM: Pentose Phosphate Pathway</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_e4p_c" stoichiometry="1"/>          <speciesReference species="M_xu5p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_f6p_c" stoichiometry="1"/>          <speciesReference species="M_g3p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TMDK1" name="thymidine kinase (ATP:thymidine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7084.1) or (7083.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_thymd_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_dtmp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TMDK1m" name="thymidine kinase (ATP:thymidine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7084.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_thymd_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_dtmp_m" stoichiometry="1"/>          <speciesReference species="M_h_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TMDPK" name="thiamine diphosphokinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (27010.1)</p>            <p>SUBSYSTEM: Thiamine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_thm_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_thmpp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TMDPP" name="thymidine phosphorylase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1890.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pi_c" stoichiometry="1"/>          <speciesReference species="M_thymd_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_2dr1p_c" stoichiometry="1"/>          <speciesReference species="M_thym_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TMDPPK" name="thiamine-diphosphate kinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Thiamine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_thmpp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_thmtp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TMDS" name="thymidylate synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7298.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dump_c" stoichiometry="1"/>          <speciesReference species="M_mlthf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dhf_c" stoichiometry="1"/>          <speciesReference species="M_dtmp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TMNDNCCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_tmndnccoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_tmndnccrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TMNDNCCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_tmndnccrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_tmndnccoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TMNDNCCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tmndnccrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tmndnccrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TMNDNCt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tmndnc_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tmndnc_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TOLBUTAMIDEte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tolbutamide_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tolbutamide_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TPI" name="triose-phosphate isomerase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7167.1) or (286016.1)</p>            <p>SUBSYSTEM: Glycolysis/Gluconeogenesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dhap_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_g3p_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TRDR" name="thioredoxin reductase (NADPH)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7296.3) or (7296.1) or (7296.4) or (7296.2)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_trdox_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_trdrd_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TRIODTHYSUFt" name="Triiodothyronine sulfate transport (diffusion)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_triodthysuf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_triodthysuf_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TRIODTHYSULT" name="Triiodothyronine Sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6817.4) or (6817.1) or (6817.3) or (6817.2) or (6817.5)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_paps_c" stoichiometry="1"/>          <speciesReference species="M_triodthy_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>          <speciesReference species="M_triodthysuf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TRIODTHYt" name="T3 transport via bicarbonate countertransport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (28234.1) or (28231.1) or (10599.1) or (6579.1) or (53919.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hco3_c" stoichiometry="1"/>          <speciesReference species="M_triodthy_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_hco3_e" stoichiometry="1"/>          <speciesReference species="M_triodthy_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TRIODTHYt2" name="T3 transport via facilitated diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6567.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_triodthy_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_triodthy_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TRIOK" name="triokinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Fructose and Mannose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_glyald_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_g3p_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TRPHYDRO2" name="L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7166.1) or (121278.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_thbpt_c" stoichiometry="1"/>          <speciesReference species="M_trp_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5htrp_c" stoichiometry="1"/>          <speciesReference species="M_thbpt4acam_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TRPO2" name="L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6999.1)</p>            <p>SUBSYSTEM: Tryptophan metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_trp_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_Lfmkynr_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TRPt" name="L-tryptophan transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (117247.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_trp_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_trp_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TSULt4_3" name="thiosulfate transport via sodium symport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6561.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="3"/>          <speciesReference species="M_tsul_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="3"/>          <speciesReference species="M_tsul_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TTDCAt" name="Tetradecanoate (n-C14:0) transport in via uniport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ttdca_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ttdca_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TTDCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1374.1) or (1375.2) or (126129.1) or (1375.4)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_tdcoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_ttdcrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TTDCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_ttdcrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_tdcoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TTDCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ttdcrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ttdcrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TYMSFt" name="Tyramine O-sulfate transport (diffusion)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tymsf_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tymsf_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TYMSULT" name="Tyramine Sulfotransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6818.3) or (6818.1) or (6817.4) or (6817.1) or (6817.3) or (6818.2) or (6817.2) or (6817.5)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_paps_c" stoichiometry="1"/>          <speciesReference species="M_tym_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_pap_c" stoichiometry="1"/>          <speciesReference species="M_tymsf_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TYRCBOX" name="L-Tyrosine carboxy-lyase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1644.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_tyr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_tym_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TYROXDAc" name="Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing) (cytosol)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (4128.1) or (4129.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_o2_c" stoichiometry="1"/>          <speciesReference species="M_tym_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4hoxpacd_c" stoichiometry="1"/>          <speciesReference species="M_h2o2_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TYRTA" name="tyrosine transaminase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2805.1)</p>            <p>SUBSYSTEM: Tyrosine metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_c" stoichiometry="1"/>          <speciesReference species="M_tyr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_34hpp_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TYRt" name="L-tyrosine transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (117247.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_tyr_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_tyr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_TYRt4" name="L-tyrosine transport in via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11254.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_tyr_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_tyr_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UAG2EMAi" name="UDP-N-acetyl-D-glucosamine 2-epimerase (Hydrolysis)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (10020.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_uacgam_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_acmana_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UAGDP" name="UDP-N-acetylglucosamine diphosphorylase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6675.1) or (91373.1)</p>            <p>SUBSYSTEM: Aminosugar Metabolism </p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_acgam1p_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_utp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ppi_c" stoichiometry="1"/>          <speciesReference species="M_uacgam_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UDPDOLPT_L" name="UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase (liver)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (29880.1)</p>            <p>SUBSYSTEM: N-Glycan Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dolp_DASH_L_c" stoichiometry="0.1"/>          <speciesReference species="M_udpg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dolglcp_DASH_L_c" stoichiometry="0.1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UDPDOLPT_U" name="UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase (uterus)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (29880.1)</p>            <p>SUBSYSTEM: N-Glycan Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dolp_DASH_U_c" stoichiometry="0.1"/>          <speciesReference species="M_udpg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dolglcp_DASH_U_c" stoichiometry="0.1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UDPG4E" name="UDPglucose 4-epimerase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2582.1) or (2582.2)</p>            <p>SUBSYSTEM: Galactose metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_udpg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_udpgal_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UDPGD" name="UDPglucose 6-dehydrogenase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7358.1)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_nad_c" stoichiometry="2"/>          <speciesReference species="M_udpg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="3"/>          <speciesReference species="M_nadh_c" stoichiometry="2"/>          <speciesReference species="M_udpglcur_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UDPGLCAter" name="UDPGlcA endoplasmic reticulum transport via UMP antiport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (23169.1)</p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_udpglcur_r" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_udpglcur_c" stoichiometry="1"/>          <speciesReference species="M_ump_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UDPGLCter" name="UDP-Glc endoplasmic reticulum transport via CMP antiport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_udpg_c" stoichiometry="1"/>          <speciesReference species="M_ump_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_udpg_r" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UDPGP" name="UDPglucose pyrophosphohydrolase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (5167.1) or (5169.1) or (5168.1)</p>            <p>SUBSYSTEM: Starch and Sucrose Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_udpg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_g1p_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UGCG" name="Ceramide glucosyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7357.1)</p>            <p>SUBSYSTEM: Sphingolipid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crm_DASH_hs_r" stoichiometry="1"/>          <speciesReference species="M_udpg_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gluside_DASH_hs_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="1"/>          <speciesReference species="M_udp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UGLT" name="UDPglucose--hexose-1-phosphate uridylyltransferase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (2592.1) or (2592.3) or (2592.2)</p>            <p>SUBSYSTEM: Galactose metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gal1p_c" stoichiometry="1"/>          <speciesReference species="M_udpg_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_g1p_c" stoichiometry="1"/>          <speciesReference species="M_udpgal_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UGT1A10r" name="UDP-glucuronosyltransferase 1-10 precursor, microsomal" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54576.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bilirub_r" stoichiometry="1"/>          <speciesReference species="M_h_r" stoichiometry="2"/>          <speciesReference species="M_udpglcur_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bilglcur_r" stoichiometry="1"/>          <speciesReference species="M_udp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UGT1A1r" name="UDP-glucuronosyltransferase 1-10 precursor, microsomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54575.1) or (54576.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estrone_r" stoichiometry="1"/>          <speciesReference species="M_udpglcur_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estroneglc_r" stoichiometry="1"/>          <speciesReference species="M_udp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UGT1A2r" name="UDP-glucuronosyltransferase 1-10 precursor, microsomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54575.1) or (54576.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_bilirub_r" stoichiometry="1"/>          <speciesReference species="M_udpglcur_r" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_bildglcur_r" stoichiometry="1"/>          <speciesReference species="M_udp_r" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UGT1A5r" name="UDP-glucuronosyltransferase 1-10 precursor, microsomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54575.1) or (54576.1)</p>            <p>SUBSYSTEM: Vitamin A Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_retn_r" stoichiometry="1"/>          <speciesReference species="M_udpglcur_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_retnglc_r" stoichiometry="1"/>          <speciesReference species="M_udp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UGT1A5r2" name="UDP-glucuronosyltransferase 1-10 precursor, microsomal (13-cis)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54576.1) or (54575.1)</p>            <p>SUBSYSTEM: Vitamin A Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retn_r" stoichiometry="1"/>          <speciesReference species="M_udpglcur_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_13_DASH_DASH_DASH_cis_DASH_DASH_DASH_retnglc_r" stoichiometry="1"/>          <speciesReference species="M_udp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UGT1A6r" name="UDP-glucuronosyltransferase 1-10 precursor, microsomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54575.1) or (54576.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_estradiol_r" stoichiometry="1"/>          <speciesReference species="M_udpglcur_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_estradiolglc_r" stoichiometry="1"/>          <speciesReference species="M_udp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UGT1A9r" name="UDP-glucuronosyltransferase 1-10 precursor, microsomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (54490.1)</p>            <p>SUBSYSTEM: Steroid Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_5adtststerone_r" stoichiometry="1"/>          <speciesReference species="M_udpglcur_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_5adtststeroneglc_r" stoichiometry="1"/>          <speciesReference species="M_udp_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK" name="UMP kinase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK2" name="UMP kinase (CTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ctp_c" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK2n" name="UMP kinase (CTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ctp_n" stoichiometry="1"/>          <speciesReference species="M_ump_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_cdp_n" stoichiometry="1"/>          <speciesReference species="M_udp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK3" name="UMP kinase (UTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ump_c" stoichiometry="1"/>          <speciesReference species="M_utp_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_udp_c" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK3n" name="UMP kinase (UTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_ump_n" stoichiometry="1"/>          <speciesReference species="M_utp_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_udp_n" stoichiometry="2"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK4" name="UMP kinase (GTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gtp_c" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gdp_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK4n" name="UMP kinase (GTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_gtp_n" stoichiometry="1"/>          <speciesReference species="M_ump_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_gdp_n" stoichiometry="1"/>          <speciesReference species="M_udp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK5" name="UMP kinase (dATP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_datp_c" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dadp_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK5n" name="UMP kinase (dATP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_datp_n" stoichiometry="1"/>          <speciesReference species="M_ump_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dadp_n" stoichiometry="1"/>          <speciesReference species="M_udp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK6" name="UMP kinase (dCTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dctp_c" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK6n" name="UMP kinase (dCTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dctp_n" stoichiometry="1"/>          <speciesReference species="M_ump_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dcdp_n" stoichiometry="1"/>          <speciesReference species="M_udp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK7" name="UMP kinase (dGTP)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dgtp_c" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dgdp_c" stoichiometry="1"/>          <speciesReference species="M_udp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPK7n" name="UMP kinase (dGTP),nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_dgtp_n" stoichiometry="1"/>          <speciesReference species="M_ump_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_dgdp_n" stoichiometry="1"/>          <speciesReference species="M_udp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UMPKn" name="UMP kinase, nuclear" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51727.1)</p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_n" stoichiometry="1"/>          <speciesReference species="M_ump_n" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_n" stoichiometry="1"/>          <speciesReference species="M_udp_n" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UNK3" name=" 2-keto-4-methylthiobutyrate transamination" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Arginine and Proline Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_2kmb_c" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_akg_c" stoichiometry="1"/>          <speciesReference species="M_met_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UPP3S" name="uroporphyrinogen-III synthase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7390.1)</p>            <p>SUBSYSTEM: Heme Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_hmbil_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_uppg3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UPPDC1" name="uroporphyrinogen decarboxylase (uroporphyrinogen III)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7389.1)</p>            <p>SUBSYSTEM: Heme Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="4"/>          <speciesReference species="M_uppg3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_co2_c" stoichiometry="4"/>          <speciesReference species="M_cpppg3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UPPN" name="b-ureidopropionase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51733.1)</p>            <p>SUBSYSTEM: Pyrimidine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_cala_c" stoichiometry="1"/>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="2"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_ala_DASH_DASH_DASH_B_c" stoichiometry="1"/>          <speciesReference species="M_co2_c" stoichiometry="1"/>          <speciesReference species="M_nh4_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_URATEt" name="urate export from cytosol" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_urate_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_urate_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_URATEtx" name="urate export from peroxisome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_urate_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_urate_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_URCN" name="urocanase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (131669.1)</p>            <p>SUBSYSTEM: Histidine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_c" stoichiometry="1"/>          <speciesReference species="M_urcan_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_4izp_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UREAt" name="Urea transport via facilitate diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (6523.1) or (6563.1) or (6528.1) or (8170.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_urea_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_urea_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_UREAtm" name="Urea transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (366.1)</p>            <p>SUBSYSTEM: Urea cycle/amino group metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_urea_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_urea_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_URIDK2m" name="uridylate kinase (dUMP), mitochondrial" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Nucleotides</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_m" stoichiometry="1"/>          <speciesReference species="M_dump_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_m" stoichiometry="1"/>          <speciesReference species="M_dudp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_URIK1" name="uridine kinase (ATP:Uridine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7371.1) or (83549.1)</p>            <p>SUBSYSTEM: Pyrimidine Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_uri_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_ump_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_URIt" name="uridine facilated transport in cytosol" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (3177.1) or (2030.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_uri_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_uri_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_URIt4" name="uridine transport in via sodium symport" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9154.2) or (9154.1) or (64078.1) or (9153.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_na1_e" stoichiometry="1"/>          <speciesReference species="M_uri_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_na1_c" stoichiometry="1"/>          <speciesReference species="M_uri_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VACCCPT1" name="carnitine O-palmitoyltransferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_crn_c" stoichiometry="1"/>          <speciesReference species="M_vacccoa_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_coa_c" stoichiometry="1"/>          <speciesReference species="M_vacccrn_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VACCCPT2" name="carnitine transferase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1376.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_coa_m" stoichiometry="1"/>          <speciesReference species="M_vacccrn_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_crn_m" stoichiometry="1"/>          <speciesReference species="M_vacccoa_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VACCCRNt" name="transport into the mitochondria (carnitine)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (788.1)</p>            <p>SUBSYSTEM: Carnitine shuttle</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_vacccrn_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_vacccrn_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VACCt" name="fatty acid transport via diffusion" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_vacc_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_vacc_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VALTAm" name="valine transaminase, mitochondiral" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (587.1)</p>            <p>SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_akg_m" stoichiometry="1"/>          <speciesReference species="M_val_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_3mob_m" stoichiometry="1"/>          <speciesReference species="M_glu_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VALt5m" name="Valine reversible mitochondrial transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_val_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_val_DASH_DASH_DASH_L_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VALtec" name="L-valine transport via diffusion (extracellular to cytosol)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (8501.1) or (124935.1)</p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_val_DASH_DASH_DASH_L_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_val_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VD3" name="Vitamin D3 formation" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Vitamin D</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_pd3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_vitd3_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VITD3Hm" name="Vitamin D-25-hydroxylase (D3)" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (1593.1)</p>            <p>SUBSYSTEM: Vitamin D</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_m" stoichiometry="1"/>          <speciesReference species="M_nadph_m" stoichiometry="1"/>          <speciesReference species="M_o2_m" stoichiometry="1"/>          <speciesReference species="M_vitd3_m" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_25hvitd3_m" stoichiometry="1"/>          <speciesReference species="M_h2o_m" stoichiometry="1"/>          <speciesReference species="M_nadp_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VITD3tm3" name="Vitamin D3 transport in mitochondria" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_vitd3_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_vitd3_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VLCS2p" name="Very-long-chain-fatty-acid-CoA ligase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11001.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_x" stoichiometry="1"/>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_dhcholestanate_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_x" stoichiometry="1"/>          <speciesReference species="M_dhcholestancoa_x" stoichiometry="1"/>          <speciesReference species="M_ppi_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_VLCSp" name="Very-long-chain-fatty-acid-CoA ligase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (11001.1)</p>            <p>SUBSYSTEM: Bile Acid Biosynthesis</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_x" stoichiometry="1"/>          <speciesReference species="M_coa_x" stoichiometry="1"/>          <speciesReference species="M_thcholstoic_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_amp_x" stoichiometry="1"/>          <speciesReference species="M_cholcoar_x" stoichiometry="1"/>          <speciesReference species="M_ppi_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_WHHDCAte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_whhdca_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_whhdca_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_WHTTDCAte" name="xenobiotic transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_whttdca_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_whttdca_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XANDp" name="xanthine dehydrogenase, peroxisomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7498.1)</p>            <p>SUBSYSTEM: Purine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_nad_x" stoichiometry="1"/>          <speciesReference species="M_xan_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_x" stoichiometry="1"/>          <speciesReference species="M_nadh_x" stoichiometry="1"/>          <speciesReference species="M_urate_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XANtx" name="xanthine diffusion in peroxisome" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Peroxisomal</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xan_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xan_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XAO2x" name="xanthine oxidase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7498.1)</p>            <p>SUBSYSTEM: Purine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_hxan_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_xan_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XAOx" name="xanthine  oxidase,peroxisomal" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (7498.1)</p>            <p>SUBSYSTEM: Purine Catabolism</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h2o_x" stoichiometry="1"/>          <speciesReference species="M_o2_x" stoichiometry="1"/>          <speciesReference species="M_xan_x" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h2o2_x" stoichiometry="1"/>          <speciesReference species="M_urate_x" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOL27OHtm" name=" 27 hydroxy cholesterol transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xol27oh_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xol27oh_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOL7AH2tm" name="lipid, flip-flop intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xol7ah2_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xol7ah2_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOL7AONEtr" name="lipid, flip-flop intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xol7aone_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xol7aone_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOLDIOLONEt" name="lipid, flip-flop intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoldiolone_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xoldiolone_r" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOLESTte" name="cholesterol ester transporter" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xolest_DASH_hs_e" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xolest_DASH_hs_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOLTRI24tc" name=" 24 trihydroxy cholesterol transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoltri24_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xoltri24_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOLTRI24te" name=" 24 trihydroxy cholesterol transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoltri24_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xoltri24_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOLTRI25tc" name=" 25 trihydroxy cholesterol transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoltri25_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xoltri25_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOLTRI25te" name=" 25 trihydroxy cholesterol transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoltri25_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xoltri25_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOLTRI27tc" name=" 27 trihydroxy cholesterol transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Endoplasmic Reticular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoltri27_r" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xoltri27_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOLTRI27te" name=" 27 trihydroxy cholesterol transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Extracellular</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoltri27_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xoltri27_e" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XOLTRIOLtm" name="lipid, flip-flop intracellular transport" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Transport, Mitochondrial</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_xoltriol_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_xoltriol_m" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XYLK" name="xylulokinase" reversible="false">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (9942.1)</p>            <p>SUBSYSTEM: Pentose and Glucuronate Interconversions</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_atp_c" stoichiometry="1"/>          <speciesReference species="M_xylu_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_adp_c" stoichiometry="1"/>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_xu5p_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XYLTD_Dr" name="xylitol dehydrogenase (D-xyulose-forming)" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: </p>            <p>SUBSYSTEM: Pentose and Glucuronate Interconversions</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_nad_c" stoichiometry="1"/>          <speciesReference species="M_xylt_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadh_c" stoichiometry="1"/>          <speciesReference species="M_xylu_DASH_DASH_DASH_D_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>      <reaction id="R_XYLUR" name="xylulose reductase" reversible="true">        <notes>          <body xmlns="http://www.w3.org/1999/xhtml">            <p>GENE_ASSOCIATION: (51181.1)</p>            <p>SUBSYSTEM: Pentose and Glucuronate Interconversions</p>          </body>        </notes>        <listOfReactants>          <speciesReference species="M_h_c" stoichiometry="1"/>          <speciesReference species="M_nadph_c" stoichiometry="1"/>          <speciesReference species="M_xylu_DASH_DASH_DASH_L_c" stoichiometry="1"/>        </listOfReactants>        <listOfProducts>          <speciesReference species="M_nadp_c" stoichiometry="1"/>          <speciesReference species="M_xylt_c" stoichiometry="1"/>        </listOfProducts>        <kineticLaw>          <math xmlns="http://www.w3.org/1998/Math/MathML">            <ci> FLUX_VALUE </ci>          </math>          <listOfParameters>            <parameter id="LOWER_BOUND" value="-1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="UPPER_BOUND" value="1000" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="FLUX_VALUE" value="0" units="mmol_per_gDW_per_hr" constant="false"/>            <parameter id="OBJECTIVE_COEFFICIENT" value="0" units="mmol_per_gDW_per_hr" constant="false"/>          </listOfParameters>        </kineticLaw>      </reaction>    </listOfReactions>  </model></sbml>