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["Table 2"]
[]
["110 celiac disease samples (Celiac peripheral blood dataset):"]
["Biological Process","Total No. of Genes","Observed No. of Genes","Expected No. of Genes","P-Value","Genes"]
["Immunity and defense",1318,68,31.36,"9.37 x 10-8","ABCC3, ADORA3, ARSB, C3AR1, C4BPA, CARD15, CAT, CCR3, CD14, CFD, CLEC1B, CLEC2B, EMR2, F2RL1, FCRL3, FCRL5, GSTM3, GSTM4, HP, HSPA8, IFIT3, IL11RA, IL18RAP, ITPR3, KIR3DL1, KLRC3, LAIR1, MARCO, NFE2L3, NUP88, OAS2, OSIL, PCNT, PPIE, PRMT2, RAD51C, RNPEP, SLC11A1"]
[]
["Amino acid metabolism",230,19,5.47,"1.34 x 10-4","ADI1, AMDHD1, AMT, ASNSD1, CBS, CPT1B, CRAT, FAS, GATM, GRHPR, HPD, MTRR, PAPSS1, PHGDH, QDPR, SHMT1, SLC7A14, SLC7A8, SLC7A9"]
[]
["Other metabolism",559,27,13.3,"1.67 x 10-2","AHSA2, AMT, ATF7IP2, AYTL1, BST1, CBR3, DEGS1, EPHX2, FDFT1, FOXRED1, FVT1, GCAT, MAP3K2, MRPL19, MTHFS, NEIL2, OAS2, PASK, PASK, PHCA, RDH13, RPS6KA2, SCP2, SCP2, UPB1, UPF2, VAMP4, ZNF333, ZNF654"]
[]
["Cell motility",352,21,8.37,"2.21 x 10-2","ARFIP1, CCR3, CD9, CDH23, CXCL5, ENC1, ITPR3, KIAA1598, LIMS2, MYH9, MYO18B, MYOM1, MYOM2, PF4V1, PTPRA, TEK, TPM2, TUBB3, VASP, VNN2, ZYX"]
[]
["Lipid, fatty acid and steroid metabolism",770,33,18.32,"3.27 x 10-2","A4GALT, ACACB, ACP6, ARSB, ARSB, CAT, CAT, CHPT1, CPT1B, CRAT, CYB5R2, CYP27A1, CYP2W1, CYP4F12, DGKQ, EBPL, FAS, FAS, FDFT1, GCDH, GPX7, HSD17B12, LIPA, LYCAT, PAQR6, PCYT1A, PHCA, PLA2G4C, PLTP, PPARBP, RNPEP, SLC37A2, SPP1, ST6GALNAC1, STARD10, SYNJ2"]
[]
["Signal transduction",3406,108,81.03,"3.59 x 10-2","ADAM2, ADORA3, AKAP10, ALS2, ARNT, ASGR2, BAIAP2, BCR, C3AR1, CCR3, CD207, CD79B, CDC42EP1, CDH2, CDH23, CEACAM21, CEACAM4, CIB1, CLEC1B, CLEC2B, CLEC4C, CNTNAP2, CXCL5, DGKQ, DSG3, DUSP14, ECGF1, EDG2, EMR1, EMR2, F2RL1, FAS, FCER1G, FCRL3, FCRL5, GHRL, GJB6, GNA11, GNAI3, GNB1L, GNB5, GP1BA, GRB2, GYPC, HP, HRASLS3, IFT88, IL11RA, IL17D, IL17E, INPP5E, INPP5E, ITPR3, KIR3DL1, KLRC3, KREMEN1, KSR1, LAIR1, LEPR, LEPREL2, LILRA3, LIMS2, LST1, MARCO, MSLN, NR2F6, NRG1, OLFM1, OR10AG1, OR56B1, OR5B2, P2RX1, PAQR6, PCDHA3, PF4V1, PRMT2, PRMT5, PTPRA, RAB14, RAB2, RAB38, RAB3IP, RAPGEF1, RCSD1, RCV1, RGS17, RHOC, RPS6KA2, RSU1, S100P, SF1, SMAD5, SNX19, SNX26, SPP1, SPSB2, STAT6, TEK, TIAM1, TMEM8, TNFAIP6, TNFRSF10B, TNNC2, TRAF4, TRPC1, TSPAN14, TSPAN3, VNN2, YWHAB"]
[]
[]
["Molecular Function","Total No. of Genes","Observed No. of Genes","Expected No. of Genes","P-Value","Genes"]
["Hydrolase",736,44,17.51,"1.23 x 10-6","ADORA3, C4BPA, CD300C, CD79B, CFD, CFD, CLEC1B, CLEC2B, FCER1G, FCRL3, FCRL5, KIR3DL1, KLRC3, LAIR1, LILRA3, LYZ, OAS2, PLTP, SPP1, TAPBPL"]
[]
["Transferase",884,45,21.03,"6.67 x 10-5","A4GALT, ADNP, AYTL1, BAZ1A, CAT, CAT, CHPT1, CHST13, CPT1B, CRAT, ECGF1, EXOSC6, EZH2, FAS, FAS, FDFT1, GALNT9, GATM, GCAT, GCNT2, GSTM3, GSTM4, GSTT1, IFT88, LIAS, LYCAT, MAP3K2, MGMT, NSUN6, NUDT18, OAS2, PAPSS1, PASK, PASK, PCYT1A, POLR1D, POLR2J, PRMT2, PYGB, RPS6KA2, SHMT1, SPDY1, ST6GALNAC1, TPST1, TRMT12, UAP1L1, WBSCR27"]
[]
["Oxidoreductase",603,33,14.35,"3.72 x 10-4","ADI1, AMT, CAT, CBR3, CD14, CD14, COX11, CYB5R2, CYP26B1, CYP27A1, CYP2W1, CYP4F12, DEGS1, ETFB, FAS, FOXRED1, FVT1, GCDH, GPX7, GRHPR, H6PD, HPD, HSD17B12, INPP5E, INPP5E, MDH2, MSRB2, MTRR, NDUFA10, PAM, PHGDH, PRDX5, QDPR, RDH13, SCP2"]
[]
["Other receptor",231,17,5.5,"9.07 x 10-3","ASGR2, CD14, CD207, CD302, CLEC1B, CLEC2B, CLEC4C, CLEC4F, CNTNAP2, FOLR3, KLRC3, KREMEN1, LEPR, MARCO, PEX7, PTPRN2, SRPRB"]
[]
[]
["90 HapMap CEU samples (HapMap B cell datasets):"]
["Molecular Function","Total No. of Genes","Observed No. of Genes","Expected No. of Genes","P-Value","Genes"]
["Lipid, fatty acid and steroid metabolism",770,44,21.26,"2.24 x 10-4","ABCA1, ABCA6, ACOX3, ACSS2, AMACR, ANXA5, ARSA, ARV1, ASCC1, CAT, CAT, CAV1, CAV2, CHPT1, CRLS1, CYB5R3, DGKQ, EBPL, ECHDC3, ELOVL5, FAAH, FAAH, FDX1, HADHA, HIBCH, HSD17B12, INSIG1, IVD, LPA, LTC4S, MCAT, OXCT2, PAQR4, PGS1, PIP5K1C, PIP5K2A, PLA2G4C, PLCB2, PLD3, PLTP, RDH5, SGPP2, SLC27A5, ST8SIA5, STARD10, TAP2"]
[]
["Intracellular protein traffic",1008,50,27.82,"2.08 x 10-3","ACTA2, ACTR1A, AMPH, ARHGEF3, CAST, CAV1, CAV2, CHML, COMT, CORO2A, CPNE1, DCTN5, EIF3S8, FXC1, GNL2, KTN1, LST1, MEGF11, MFN1, MYO1E, MYOM2, PEX14, PEX5, PEX6, PEX7, POMZP3, PPIL3, RAB15, RAB31, RAB40B, RAMP1, RNF10, SCAMP3, SEC31A, SNAP29, SNX11, SNX16, SPG7, STXBP2, TIMM10, TIMM22, TNPO3, TRAPPC4, TUBB2A, TUBB2B, TUBB6, VAMP1, VPS11, WDR60, ZFYVE21"]
[]
["Protein metabolism and modification",3040,117,83.92,"4.53 x 10-3","ABHD4, ADAM21, AIM1, AMFR, ANG, B3GALNT1, B4GALNT3, B4GALT1, BLK, CAMKK2, CAPN12, CAST, CCDC126, CCT8, CDC7, CDK3, CDKN1A, CDKN1A, COX11, CSNK2A1, CSNK2A1, CSNK2B, CSTB, CTSH, CTSK, CTSS, DUSP18, EDEM1, EIF2B2, EIF3S8, EIF5, EIF5A, EPHB2, ERAL1, EXTL2, FBXO36, FDX1, FUT10, GFM1, GSG2, GUF1, HADHA, HLCS, HSPA1B, HSPA1B, IGF1R, JAK1, LPA, MAK10, MAN1A2, MAP2K2, MAP3K2, MAPK9, MASTL, MRPL14, MRPL21, MRPL27, MRPL28, MRPL30, MRPL32, MRPL36, MRPL43, MYST3, NDUFAF1, NPEPL1, P4HA2, PACSIN2, PAM, PCSK2, PIGF, PPIL3, PRKCB1, PTPN3, QRSL1, RPL12, RPL14, RPL37, RPL8, RPLP2, RPS16, RPS6KB2, RPS9, SCRN2, SDF2, SERPINA1, SERPINB1, SERPINB10, SERPINB9, SMURF2, SPG7, SPI1, SPINT2, SQSTM1, ST8SIA5, STK25, STK32C, STYXL1, SURF1, TARSL2, TBCA, TESK2, TIMP3, TRIM4, TRIM63, TRPM7, TTC3, TXNDC5, UBA52, UBE1L, UBE2G1, UBE2L3, UBE2O, UBE3B, UGCGL1, ULK3, USP36, VAMP4, WARS2, WFDC3, ZRANB1"]
[]
["Peroxisome transport",14,5,0.39,"7.47 x 10-3","PEX14, PEX5, PEX6, PEX7, RNF10"]
[]
["T-cell mediated immunity",194,16,5.36,"2.00 x 10-2","CD69, CTSS, HLA-B, HLA-C, HLA-DOB, HLA-DQA1, HLA-DQA2, HLA-DRB5, HLA-H,HFE, LTBR, LTC4S, SLFN5, SQSTM1, TAPBPL, TNFRSF25"]
[]
[]
["Molecular Function","Total No. of Genes","Observed No. of Genes","Expected No. of Genes","P-Value","Genes"]
["Transferase",884,48,24.4,"3.02 x 10-4","B3GALNT1, B3GALTL, B4GALNT3, B4GALT1, CAT, CAT, CCDC126, CDKN1A, CHML, CHPT1, COMT, CRLS1, ECGF1, ECHDC3, ELOVL5, EXTL2, FTSJ2, FTSJ3, FUT10, GSTT1, HIBCH, LCMT1, LTC4S, MAK10, MAP2K2, MAP3K2, MCAT, METTL4, MGMT, MYST3, NAPRT1, NMNAT3, NSUN4, OXCT2, PGS1, PIGF, POFUT2, POLR2E, POLR2J, QRSL1, RG9MTD3, SDF2, SETD1A, SHMT1, ST8SIA5, STK25, TGM5, UGCGL1, WBSCR27"]
[]
["Major histocompatibility complex antigen",46,9,1.27,"1.18 x 10-3","HLA-B, HLA-C, HLA-DOB, HLA-DQA1, HLA-DQA2, HLA-DRB5, HLA-H,HFE, OCIAD2"]
["Hydrolase",736,39,20.32,"3.33 x 10-3","AMDHD1, ANG, ARSA, ATHL1, ATP13A1, ATP9B, CHI3L2, CHIA, COMT, DCTD, DDX58, DEADC1, DNASE1L3, DPYSL4, FAAH, FAAH, FAHD1, GAA, GNL2, GNPDA1, GPLD1, GUF1, HDAC4, MAN1A2, MANEAL, MCMDC1, MTHFD1L, NT5C3L, NUDT2, PLA2G4C, PLCB2, PLD3, PPA2, PTER, QRSL1, RAD18, RAD51, SMPDL3B, UROS, ZRANB1"]
[]
["Defense/immunity protein",369,22,10.19,"2.32 x 10-2","C1QTNF4, C3, CD69, CD79B, CLEC2B, COLEC10, FNDC6, GSG2, HLA-B, HLA-C, HLA-DOB, HLA-DQA1, HLA-DQA2, HLA-DRB5, HLA-H,HFE, KLRC4, KLRG1, OCIAD2, PLTP, PRR4, TAPBPL"]
[]
["Select regulatory molecule",1190,51,32.85,"4.49 x 10-2","AKAP10, AKAP3, ANG, ANP32A, ARHGEF3, CAST, CAV1, CAV2, CCDC88, CDKN1A, CDKN1A, CHML, CSNK2B, CSTB, DUSP18, EIF2B2, EIF5, ERAL1, FARP2, GBP3, GNA12, GNG2, GTPBP5, GTPBP9, GUF1, KCTD7, KIAA0141, LPA, LRRC44, LST1, PEBP1, PIK3R1, PPP1R3B, PROCR, RAB15, RAB31, RAB40B, RABGAP1L, RALB, SERPINA1, SERPINB1, SERPINB10, SERPINB9, SPI1, SPINT2, TBC1D1, TBC1D4, TIMP3, TIRAP, VPS24, WFDC3"]
[]
["Ligase",468,25,12.92,"4.80 x 10-2","ACSS2, AMFR, ECHDC3, FBXO36, HIBCH, HLCS, MDM4, MTHFD1L, MTHFS, MTHFSD, PAM, PAM, QRSL1, RAD18, SMURF2, TARSL2, TRIM4, TRIM63, TSG101, TTC3, UBE1L, UBE2G1, UBE2L3, UBE2O, UBE3B, WARS2"]

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