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["© 2000-2014 Ingenuity Systems, Inc. All rights reserved."]
["Ingenuity Canonical Pathways"," -log(p-value)","Ratio","Molecules"]
["Antigen Presentation Pathway","5.94E00","3.33E-01","HLA-DMA,HLA-A,HLA-B,HLA-DQA1,CIITA,HLA-DRB1,HLA-G,HLA-DQB2,HLA-C,HLA-F,HLA-DQA2,TAP2,HLA-E,HLA-DRB5"]
["Virus Entry via Endocytic Pathways","5.87E00","2.28E-01","FYN,AP2M1,PIK3CA,PIK3C2A,ITSN1,HLA-A,HLA-B,ITGA6,ITGA5,KRAS,AP1B1,PIK3R3,RRAS2,HLA-C,FLNA,FLNC,MRAS,ITGA1,PRKD3,ITGB5,DNM2,ITGA4,PRKCB"]
["IL-4 Signaling","5E00","2.41E-01","HLA-DMA,PTPN6,PIK3CA,JAK1,PIK3C2A,NFATC3,TYK2,HLA-DQA1,HLA-DRB1,KRAS,HLA-DQB1,JAK2,PIK3R3,SHC1,NFAT5,RRAS2,RPS6KB2,MRAS,HLA-DRB5"]
["STAT3 Pathway","4.43E00","2.25E-01","PTPN6,TGFBR3,FLT1,SOCS2,TYK2,FLT4,FGFR2,KRAS,JAK2,DDR1,MAP3K12,PIAS3,RRAS2,MAP2K2,CISH,MRAS,EGFR,PDGFRB"]
["CNTF Signaling","4.33E00","2.59E-01","PIK3CA,JAK1,PIK3C2A,TYK2,KRAS,JAK2,PIK3R3,LIFR,RRAS2,MAP2K2,MRAS,RPS6KB2,RPS6KA4,STAT1"]
["Molecular Mechanisms of Cancer","4.28E00","1.34E-01","JAK1,ADCY4,NCSTN,KRAS,MAP2K2,CCND3,MRAS,ARHGEF11,GNA13,GSK3B,HIPK2,PRKD3,TP53,CASP3,ARHGEF15,TYK2,PTCH1,ARHGEF17,RHOJ,APC,PIK3R3,ADCY9,GAB1,ARHGEF6,PLCB3,NOTCH1,ARHGEF10,FYN,PIK3CA,RALA,LRP6,JAK2,BRAF,SHC1,RHOT1,MAP3K7,CTNNB1,BMP1,PRKDC,PIK3C2A,GNA12,NAIP,BMP5,RRAS2,FZD4,NF1,BMP6,ADCY7,LRP1,PRKCB,CTNND1"]
["Graft-versus-Host Disease Signaling","4.23E00","2.65E-01","HLA-DMA,HLA-A,HLA-B,HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-G,HLA-C,IL1RN,IL1B,HLA-F,HLA-E,HLA-DRB5"]
["VEGF Family Ligand-Receptor Interactions","4.18E00","2.05E-01","PIK3CA,PIK3C2A,PLA2G10,FLT1,FLT4,PLA2G4C,KRAS,NOS3,PIK3R3,VEGFA,SHC1,RRAS2,MAP2K2,MRAS,FIGF,PLA2G4F,PRKD3,PRKCB"]
["Protein Ubiquitination Pathway","4.13E00","1.52E-01","HLA-A,DNAJB4,HSPA1A/HSPA1B,PSMB10,HSPB2,CUL1,HSPB8,FBXW7,SKP1,ANAPC1,HSPA1L,DNAJB13,USP48,USO1,PAN2,HSPA4,USP10,NEDD4L,HSPB6,DNAJC9,UBE2Q1,USP43,USP36,DNAJC19,HLA-B,USP19,PSMA1,UBE3A,USP32,HLA-C,CUL2,PSMA5,UBR1,HSPA13,DNAJC18,ANAPC5,PSMD1,DNAJB6,UBC,TAP2,DNAJB5"]
["Caveolar-mediated Endocytosis Signaling","3.96E00","2.05E-01","FYN,ITSN1,HLA-A,HLA-B,ITGA6,ITGA5,DYRK3,ITGAE,FLNA,HLA-C,FLNC,ITGAV,ITGA1,ITGB5,DNM2,EGFR,ITGA4"]
["SAPK/JNK Signaling","3.94E00","1.94E-01","TP53,PIK3CA,MAP2K7,DUSP8,PIK3C2A,NFATC3,GNA12,KRAS,MAP3K4,PIK3R3,MAP3K12,MINK1,SHC1,RRAS2,GAB1,MAP3K7,ZAK,MRAS,GNA13,MAP4K4"]
["Phospholipase C Signaling","3.87E00","1.43E-01","FYN,FCGR2C,RALA,NFATC3,ADCY4,PLA2G10,HDAC10,KRAS,SHC1,NFAT5,MAP2K2,AHNAK,RHOT1,MRAS,ARHGEF11,PLA2G4F,MARCKS,GNA13,PRKD3,ITGA4,ARHGEF15,PLA2G4C,ITGA5,RHOJ,ARHGEF17,ITPR1,HDAC5,CD3G,ADCY9,RRAS2,ARHGEF6,PPP1R12B,PLCB3,PPP1R12A,ADCY7,ARHGEF10,PRKCB"]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency","3.85E00","1.91E-01","TP53,PIK3CA,JAK1,PIK3C2A,TYK2,KRAS,JAK2,BMP5,APC,LIFR,PIK3R3,SHC1,RRAS2,FZD4,MAP2K2,GAB1,MRAS,GATA6,GSK3B,BMP6,CTNNB1,BMP1"]
["JAK/Stat Signaling","3.83E00","2.25E-01","PIK3CA,PTPN6,JAK1,PIK3C2A,SOCS2,TYK2,KRAS,JAK2,PIK3R3,SHC1,PIAS3,RRAS2,MAP2K2,CISH,MRAS,STAT1"]
["OX40 Signaling Pathway","3.82E00","2.15E-01","HLA-DMA,HLA-A,HLA-B,HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-G,CD3G,HLA-DQB2,HLA-C,HLA-F,HLA-DQA2,HLA-E,HLA-DRB5"]
["Allograft Rejection Signaling","3.8E00","2.13E-01","HLA-DMA,HLA-A,HLA-B,HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-G,HLA-DQB2,HLA-C,HLA-F,HLA-DQA2,HLA-E,HLA-DRB5"]
["Cdc42 Signaling","3.57E00","1.56E-01","HLA-DMA,RALA,HLA-A,HLA-B,HLA-DQA1,ITGA5,HLA-DRB1,MYLK,HLA-DQB1,APC,HLA-G,CD3G,WASL,HLA-DQB2,HLA-C,ARHGEF6,PPP1R12B,PPP1R12A,GSK3B,HLA-DQA2,HLA-F,HLA-DRB5,HLA-E,ITGA4"]
["IL-3 Signaling","3.52E00","2.13E-01","PIK3R3,SHC1,CSF2RB,PIK3CA,PTPN6,RRAS2,JAK1,MAP2K2,IL3RA,PIK3C2A,MRAS,KRAS,JAK2,STAT1,PRKD3,PRKCB"]
["NRF2-mediated Oxidative Stress Response","3.21E00","1.51E-01","PIK3CA,DNAJB4,HSPB8,GCLC,KRAS,DNAJB13,GSTT2/GSTT2B,MAP2K2,MAP3K7,KEAP1,ABCC1,MRAS,JUND,GSK3B,PRKD3,MAP2K7,PIK3C2A,DNAJC9,DNAJC19,BACH1,PIK3R3,RRAS2,MGST2,DNAJC18,DNAJB6,AOX1,EIF2AK3,DNAJB5,PRKCB"]
["PI3K/AKT Signaling","3.18E00","1.47E-01","TP53,PIK3CA,JAK1,TYK2,ITGA5,KRAS,JAK2,NOS3,PIK3R3,SHC1,PPP2R1A,RRAS2,MAP2K2,GAB1,RPS6KB2,MRAS,MAP3K8,PPP2R5C,GSK3B,CTNNB1,PPP2R1B,ITGA4"]
["Thrombopoietin Signaling","3.17E00","2.03E-01","PIK3R3,SHC1,PIK3CA,RRAS2,MAP2K2,PIK3C2A,MRAS,IRS2,KRAS,JAK2,STAT1,PRKD3,PRKCB"]
["Autoimmune Thyroid Disease Signaling","3.16E00","1.96E-01","HLA-G,HLA-DMA,HLA-A,HLA-C,HLA-B,HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-F,HLA-DRB5,HLA-E"]
["Type I Diabetes Mellitus Signaling","3.15E00","1.69E-01","HLA-DMA,MAP2K7,JAK1,CASP3,HLA-A,SOCS2,HLA-B,HLA-DQA1,HLA-DRB1,JAK2,HLA-DQB1,HLA-G,CD3G,HLA-C,MAP3K7,IL1B,STAT1,HLA-F,HLA-DRB5,HLA-E"]
["Role of Tissue Factor in Cancer","3.1E00","1.59E-01","TP53,FYN,PIK3CA,PIK3C2A,CASP3,GNA12,ITGA6,KRAS,JAK2,PIK3R3,VEGFA,F10,RRAS2,MRAS,ITGAV,IL1B,RPS6KA4,GNA13,ITGB5,EGFR"]
["Actin Nucleation by ARP-WASP Complex","3.09E00","1.94E-01","NCK2,RRAS2,WASL,PPP1R12C,RHOT1,GNA12,PPP1R12B,MRAS,PPP1R12A,ITGA5,KRAS,RHOJ,ITGA4"]
["Notch Signaling","3.04E00","2.38E-01","MAML2,NOTCH4,DLL1,NOTCH2,NOTCH3,JAG2,NUMB,NCSTN,DLL4,NOTCH1"]
["Reelin Signaling in Neurons","2.97E00","1.88E-01","FYN,PIK3CA,MAP2K7,PIK3C2A,ARHGEF15,ITGA6,ITGA5,VLDLR,PIK3R3,APBB1,ARHGEF6,ITGA1,ARHGEF11,GSK3B,ARHGEF10,ITGA4"]
["CTLA4 Signaling in Cytotoxic T Lymphocytes","2.94E00","1.79E-01","FYN,PTPN6,PIK3CA,AP2M1,PIK3C2A,HLA-A,HLA-B,AP1B1,JAK2,CD8A,CD8B,PIK3R3,CD3G,PPP2R1A,HLA-C,PPP2R5C,PPP2R1B"]
["Endothelin-1 Signaling","2.94E00","1.44E-01","PIK3CA,PLA2G10,ADCY4,KRAS,NOS3,BRAF,SHC1,MRAS,PLA2G4F,ECE1,GNA13,PRKD3,PNPLA8,PIK3C2A,CASP3,EDNRB,GNA12,PLA2G4C,ITPR1,PIK3R3,ADCY9,RRAS2,GAB1,SHC2,PLCB3,ADCY7,PRKCB"]
["Role of JAK2 in Hormone-like Cytokine Signaling","2.92E00","2.57E-01","SHC1,PTPN6,JAK1,TYK2,SOCS2,IRS2,JAK2,STAT1,SH2B1"]
["Mouse Embryonic Stem Cell Pluripotency","2.92E00","1.82E-01","TP53,PIK3CA,JAK1,PIK3C2A,TYK2,KRAS,JAK2,APC,LIFR,PIK3R3,FZD4,RRAS2,MAP2K2,MAP3K7,MRAS,GSK3B,DVL2,CTNNB1"]
["Aldosterone Signaling in Epithelial Cells","2.91E00","1.5E-01","PIK3CA,PIK3C2A,DNAJC9,HSPA1A/HSPA1B,DNAJB4,HSPB2,DNAJC19,HSPB8,KRAS,ITPR1,HSPA1L,DNAJB13,PIK3R3,HSPA4,MAP2K2,DNAJC18,HSPA13,PLCB3,DNAJB6,SCNN1B,PIP4K2A,PRKD3,DNAJB5,HSPB6,PRKCB"]
["Prolactin Signaling","2.89E00","1.79E-01","PIK3R3,SHC1,FYN,PIK3CA,RRAS2,MAP2K2,SP1,PIK3C2A,SOCS2,MRAS,KRAS,JAK2,STAT1,PRKD3,PRKCB"]
["PAK Signaling","2.88E00","1.55E-01","PIK3CA,PIK3C2A,CASP3,PAK1IP1,ITGA5,MYLK,KRAS,PIK3R3,NCK2,SHC1,RRAS2,WASL,MAP2K2,ARHGEF6,MRAS,ITGA4,PDGFRB"]
["Integrin Signaling","2.88E00","1.46E-01","FYN,PIK3CA,RALA,MYLK,KRAS,ITGAE,NCK2,BRAF,SHC1,WASL,MAP2K2,RHOT1,MRAS,ITGAV,GSK3B,ITGB5,ACTN1,ITGA4,PIK3C2A,ASAP1,ITGA6,ITGA5,RHOJ,PIK3R3,ARHGAP5,RRAS2,PPP1R12B,PPP1R12A,ITGA1,CAPN9"]
["Thrombin Signaling","2.82E00","1.4E-01","PIK3CA,ADCY4,MYLK,KRAS,GATA2,SHC1,MAP2K2,RHOT1,MRAS,GATA6,ARHGEF11,GNA13,PRKD3,EGFR,PIK3C2A,ARHGEF15,GNA12,RHOJ,ITPR1,PIK3R3,ADCY9,RRAS2,ARHGEF6,PPP1R12B,PLCB3,PPP1R12A,ARHGEF10,ADCY7,PRKCB"]
["Oncostatin M Signaling","2.72E00","2.57E-01","SHC1,JAK1,RRAS2,MAP2K2,TYK2,MRAS,KRAS,JAK2,STAT1"]
["Breast Cancer Regulation by Stathmin1","2.71E00","1.37E-01","PIK3CA,ADCY4,KRAS,SHC1,MAP2K2,MRAS,PPP2R5C,ARHGEF11,GNA13,PPP1CA,PRKD3,TP53,PIK3C2A,ARHGEF15,ARHGEF17,ITPR1,CDK1,PIK3R3,ADCY9,PPP2R1A,TUBA1A,RRAS2,ARHGEF6,PLCB3,PPP1R12A,ARHGEF10,PPP2R1B,ADCY7,PRKCB"]
["Sertoli Cell-Sertoli Cell Junction Signaling","2.71E00","1.39E-01","SPTBN1,TGFBR3,KRAS,MAP3K4,NOS3,MAP2K2,MAP3K7,KEAP1,MRAS,SPTB,GSK3B,CTNNB1,ACTN1,ITGA4,MAP2K7,TJP2,TJP1,ITGA5,MAP3K12,TJP3,PRKG1,RRAS2,TUBA1A,JAM3,ZAK,MAP3K8,SPTAN1"]
["GM-CSF Signaling","2.66E00","1.94E-01","PIK3R3,SHC1,CSF2RB,PIK3CA,RRAS2,MAP2K2,PIK3C2A,CISH,MRAS,KRAS,JAK2,STAT1,PRKCB"]
["PDGF Signaling","2.65E00","1.74E-01","PIK3CA,JAK1,PIK3C2A,TYK2,KRAS,JAK2,PIK3R3,SHC1,RRAS2,MAP2K2,MRAS,SPHK1,STAT1,PRKCB,PDGFRB"]
["Biotin-carboxyl Carrier Protein Assembly","2.61E00","2E-01","ACACB,ACACA,BTD"]
["UVC-Induced MAPK Signaling","2.59E00","2.27E-01","BRAF,TP53,RRAS2,MAP2K2,MRAS,KRAS,SMPD1,PRKD3,EGFR,PRKCB"]
["PTEN Signaling","2.56E00","1.44E-01","PIK3CA,CASP3,TGFBR3,FLT1,FLT4,FGFR2,PREX2,ITGA5,KRAS,DDR1,PIK3R3,SHC1,RRAS2,MAP2K2,MRAS,RPS6KB2,GSK3B,EGFR,ITGA4,PDGFRB"]
["UVA-Induced MAPK Signaling","2.52E00","1.7E-01","TP53,PIK3CA,PIK3C2A,CASP3,SMPD1,TNKS2,KRAS,PIK3R3,RRAS2,TIPARP,MRAS,RPS6KB2,PLCB3,RPS6KA4,STAT1,EGFR"]
["Colorectal Cancer Metastasis Signaling","2.5E00","1.28E-01","PIK3CA,JAK1,MSH3,ADCY4,LRP6,KRAS,JAK2,VEGFA,BRAF,MAP2K2,RHOT1,MRAS,FIGF,GSK3B,CTNNB1,STAT1,PTGER4,EGFR,MMP19,TP53,PIK3C2A,CASP3,MMP28,TYK2,RHOJ,APC,PIK3R3,ADCY9,RRAS2,FZD4,MSH6,ADCY7,LRP1"]
["Germ Cell-Sertoli Cell Junction Signaling","2.46E00","1.44E-01","PIK3CA,MAP2K7,PIK3C2A,TJP1,ITGA6,LAMC3,RHOJ,KRAS,MAP3K4,GSN,PIK3R3,MAP3K12,WASL,RRAS2,TUBA1A,MAP2K2,RHOT1,MAP3K7,KEAP1,MRAS,MAP3K8,CTNNB1,ACTN1,CTNND1"]
["NF-κB Activation by Viruses","2.44E00","1.71E-01","PIK3CA,PIK3C2A,ITGA6,ITGA5,KRAS,PIK3R3,RRAS2,ITGAV,MRAS,ITGA1,PRKD3,ITGB5,PRKCB,ITGA4"]
["PKCθ Signaling in T Lymphocytes","2.43E00","1.39E-01","HLA-DMA,FYN,PIK3CA,PIK3C2A,NFATC3,HLA-DQA1,HLA-DRB1,KRAS,MAP3K4,HLA-DQB1,PIK3R3,CD3G,MAP3K12,NFAT5,RRAS2,MAP3K7,MRAS,MAP3K8,HLA-DRB5"]
["ILK Signaling","2.42E00","1.36E-01","PIK3CA,FN1,VEGFA,NCK2,TGFB1I1,RHOT1,FLNA,FIGF,PPP2R5C,IRS2,GSK3B,CTNNB1,ITGB5,ACTN1,DSP,PIK3C2A,CASP3,LIMS2,RHOJ,PIK3R3,PPP2R1A,FLNC,ARHGEF6,MYH9,PPP1R12A,RPS6KA4,PPP2R1B"]
["VEGF Signaling","2.42E00","1.51E-01","PIK3R3,VEGFA,SHC1,PIK3CA,PTPN6,RRAS2,MAP2K2,PIK3C2A,FLT1,FLT4,MRAS,FIGF,KRAS,NOS3,ACTN1,PRKCB"]
["B Cell Receptor Signaling","2.39E00","1.4E-01","FCGR2C,PTPN6,PIK3CA,MAP2K7,PIK3C2A,NFATC3,KRAS,MAP3K4,PIK3R3,SHC1,MAP3K12,EBF1,NFAT5,RRAS2,MAP2K2,GAB1,MAP3K7,PAG1,RPS6KB2,MRAS,PIK3AP1,MAP3K8,GSK3B,PRKCB"]
["Protein Kinase A Signaling","2.38E00","1.2E-01","AKAP12,HIST1H1C,DUSP8,PTPN13,NFATC3,DUSP6,ADCY4,LIPE,MYLK,NOS3,ANAPC1,DUSP2,AKAP11,BRAF,NFAT5,MAP2K2,FLNA,DUSP7,GSK3B,GNA13,CTNNB1,DUSP12,PPP1CA,PRKD3,MTMR3,PDE2A,PTPRG,PTPRE,PTPN6,PTCH1,ITPR1,PDE4D,PTPRM,ADCY9,PTPRU,FLNC,PTPRB,PTPRS,ANAPC5,PPP1R12A,PLCB3,AKAP9,ADCY7,PTPN21,CDC27,DUSP16,PRKCB"]
["NGF Signaling","2.37E00","1.49E-01","TP53,PIK3CA,PIK3C2A,TRIO,SMPD1,KRAS,MAP3K4,PIK3R3,SHC1,MAP3K12,RRAS2,MAP2K2,GAB1,MAP3K7,RPS6KB2,MRAS,MAP3K8,RPS6KA4"]
["Paxillin Signaling","2.32E00","1.48E-01","PIK3CA,PIK3C2A,ITGA6,ITGA5,KRAS,ITGAE,PIK3R3,NCK2,RRAS2,ARFIP2,ARHGEF6,MRAS,ITGAV,ITGA1,ACTN1,ITGB5,ITGA4"]
["Role of JAK1 and JAK3 in γc Cytokine Signaling","2.32E00","1.82E-01","PIK3R3,SHC1,PIK3CA,JAK1,RRAS2,FES,PIK3C2A,MRAS,IRS2,KRAS,JAK2,STAT1"]
["Role of NFAT in Regulation of the Immune Response","2.31E00","1.28E-01","HLA-DMA,FYN,FCGR2C,PIK3CA,PIK3C2A,NFATC3,GNA12,HLA-DQA1,CSNK1A1,HLA-DRB1,KRAS,ITPR1,HLA-DQB1,FCGR1A,CABIN1,PIK3R3,CD3G,RRAS2,NFAT5,MAP2K2,MRAS,PLCB3,GSK3B,GNA13,HLA-DRB5"]
["ERK/MAPK Signaling","2.29E00","1.3E-01","FYN,PIK3CA,DUSP6,HSPB2,PLA2G10,KRAS,DUSP2,BRAF,SHC1,MAP2K2,MRAS,PLA2G4F,PPP2R5C,STAT1,PPP1CA,ITGA4,PPARG,PIK3C2A,PLA2G4C,ITGA5,PIK3R3,PPP2R1A,RRAS2,PPP1R12A,RPS6KA4,PPP2R1B,PRKCB"]
["Macropinocytosis Signaling","2.29E00","1.69E-01","PIK3R3,MET,MRC1,PIK3CA,RRAS2,ABI1,PIK3C2A,MRAS,ITGA5,KRAS,PRKD3,ITGB5,PRKCB"]
["Renin-Angiotensin Signaling","2.29E00","1.44E-01","PTPN6,PIK3CA,PIK3C2A,ADCY4,KRAS,ITPR1,JAK2,PIK3R3,SHC1,ADCY9,RRAS2,MAP2K2,SHC2,MRAS,STAT1,ADCY7,PRKD3,PRKCB"]
["Melanocyte Development and Pigmentation Signaling","2.27E00","1.61E-01","PIK3CA,PTPN6,PIK3C2A,ADCY4,KRAS,PIK3R3,SHC1,ADCY9,RRAS2,MAP2K2,MRAS,RPS6KB2,KIT,RPS6KA4,ADCY7"]
["Gap Junction Signaling","2.26E00","1.31E-01","PIK3CA,PIK3C2A,ADCY4,CSNK1A1,KRAS,ITPR1,PIK3R3,ADCY9,TUBA1A,ADRB1,RRAS2,PRKG1,MAP2K2,SP1,NPR1,MRAS,SGSM3,PLCB3,CTNNB1,ADCY7,PRKD3,EGFR,PRKCB"]
["3-phosphoinositide Biosynthesis","2.24E00","1.28E-01","PTPN6,PIK3CA,PPP1R12C,DUSP8,PIK3C2A,PTPN13,DOT1L,MDP1,PPTC7,PPIP5K1,NUDT2,PPM1K,PTPRM,DUSP2,PIK3R3,TNS3,PPP1R16B,PPP1R12A,PPM1F,PALD1,PIP4K2A,DUSP16"]
["Acute Myeloid Leukemia Signaling","2.23E00","1.67E-01","PIK3R3,BRAF,CSF3R,CSF2RB,MAP2K7,PIK3CA,RRAS2,MAP2K2,PIK3C2A,RPS6KB2,MRAS,KIT,KRAS,PML"]
["Thyroid Cancer Signaling","2.2E00","2.05E-01","PPARG,BRAF,TP53,SHC1,RRAS2,MAP2K2,MRAS,KRAS,CTNNB1"]
["FAK Signaling","2.17E00","1.43E-01","FYN,PIK3CA,PIK3C2A,ASAP1,ITGA5,KRAS,PIK3R3,RRAS2,MAP2K2,ARHGEF6,MRAS,CAPN9,TNS1,EGFR,ITGA4"]
["Axonal Guidance Signaling","2.17E00","1.09E-01","SLIT3,ADAMTS8,ITSN1,EPHB2,NFATC3,KRAS,NCK2,VEGFA,MAP2K2,MRAS,FIGF,ARHGEF11,SRGAP2,GNA13,GSK3B,CHMP1A,PRKD3,ITGA4,PAPPA,FES,ARHGEF15,PTCH1,ITGA5,HERC2,PIK3R3,ARHGEF6,PLCB3,FYN,ERAP2,PIK3CA,ADAMTS7,RGS3,SEMA6A,SHC1,WASL,NFAT5,PLXNB1,SEMA4A,SEMA3F,BMP1,SEMA3G,PLXNA1,PIK3C2A,GNA12,SLIT2,BMP5,TUBA1A,FZD4,RRAS2,SEMA3C,BMP6,PRKCB"]
["Role of CHK Proteins in Cell Cycle Checkpoint Control","2.17E00","1.86E-01","TP53,PPP2R1A,RAD17,ATMIN,SLC19A1,PPP2R5C,RFC1,TLK2,PPP2R1B,CDK1,RAD50"]
["Insulin Receptor Signaling","2.16E00","1.38E-01","FYN,PIK3CA,JAK1,PIK3C2A,LIPE,KRAS,JAK2,GRB10,PIK3R3,SHC1,RRAS2,MAP2K2,GAB1,RPS6KB2,MRAS,PPP1R12A,IRS2,GSK3B,SCNN1B,PPP1CA"]
["Superpathway of Inositol Phosphate Compounds","2.14E00","1.16E-01","PTPN6,PIK3CA,DUSP8,PPP1R12C,PIK3C2A,PTPN13,SEC16A,DOT1L,PPTC7,MDP1,PPIP5K1,NUDT2,PPM1K,PTPRM,DUSP2,PIK3R3,TNS3,ITPKB,PPP1R16B,PLCB3,PPP1R12A,PPM1F,IP6K2,PALD1,PIP4K2A,DUSP16"]
["Nitric Oxide Signaling in the Cardiovascular System","2.13E00","1.36E-01","PDE2A,PIK3CA,PIK3C2A,FLT1,FLT4,ARG2,ITPR1,NOS3,VEGFA,PIK3R3,PRKG1,ADRB1,MAP2K2,FIGF,PRKD3,PRKCB"]
["IL-9 Signaling","2.13E00","2E-01","PIK3R3,PIK3CA,JAK1,PIK3C2A,CISH,SOCS2,IRS2,STAT1"]
["CDK5 Signaling","2.13E00","1.56E-01","LAMA5,ADCY4,ITGA6,KRAS,ADCY9,PPP2R1A,RRAS2,MAP2K2,LAMB1,MRAS,PPP1R12A,PPP2R5C,PPP1CA,ADCY7,PPP2R1B"]
["Hereditary Breast Cancer Signaling","2.12E00","1.4E-01","TP53,POLR2J2/POLR2J3,PIK3CA,PIK3C2A,HDAC10,RFC1,KRAS,SMARCA4,CDK1,RAD50,HDAC5,PIK3R3,RRAS2,POLR2A,MRAS,MSH6,SLC19A1,UBC"]
["ErbB2-ErbB3 Signaling","2.11E00","1.77E-01","PIK3R3,SHC1,PIK3CA,RRAS2,SP1,MAP2K2,PIK3C2A,TYK2,MRAS,KRAS,GSK3B"]
["Telomerase Signaling","2.09E00","1.58E-01","TP53,PIK3CA,PIK3C2A,HDAC10,KRAS,HDAC5,PIK3R3,SHC1,PPP2R1A,RRAS2,SP1,MAP2K2,MRAS,PPP2R5C,PPP2R1B,EGFR"]
["PPARα/RXRα Activation","2.08E00","1.28E-01","MAP2K7,TGFBR3,ADCY4,NR2C2,KRAS,JAK2,MED12,TGS1,ABCA1,ADCY9,SHC1,RRAS2,MAP2K2,MAP3K7,MRAS,PLCB3,IL1B,NCOR1,NCOR2,GOT2,ADCY7,MAP4K4,ITGB5,PRKCB"]
["Melanoma Signaling","2.06E00","1.8E-01","PIK3R3,BRAF,TP53,PIK3CA,RRAS2,MAP2K2,PIK3C2A,MRAS,KRAS"]
["Calcium-induced T Lymphocyte Apoptosis","1.99E00","1.64E-01","CD3G,HLA-DMA,HLA-DQA1,NR4A1,HLA-DRB1,HLA-DQB1,ITPR1,PRKD3,HLA-DRB5,CABIN1,PRKCB"]
["ErbB4 Signaling","1.99E00","1.64E-01","PIK3R3,SHC1,PIK3CA,RRAS2,MAP2K2,PIK3C2A,MRAS,NCSTN,KRAS,PRKD3,PRKCB"]
["D-myo-inositol-5-phosphate Metabolism","1.98E00","1.29E-01","PTPN6,PPP1R12C,DUSP8,PTPN13,DOT1L,MDP1,PPTC7,PPIP5K1,NUDT2,PPM1K,PTPRM,DUSP2,TNS3,PPP1R16B,PPP1R12A,PLCB3,PPM1F,PALD1,PIP4K2A,DUSP16"]
["3-phosphoinositide Degradation","1.98E00","1.29E-01","PTPN6,PPP1R12C,DUSP8,PTPN13,DOT1L,MDP1,PPTC7,PPIP5K1,NUDT2,PPM1K,PTPRM,DUSP2,INPP4A,TNS3,PPP1R16B,PPP1R12A,PPM1F,PALD1,MTMR3,DUSP16"]
["HGF Signaling","1.96E00","1.45E-01","PIK3CA,MAP2K7,PIK3C2A,KRAS,MAP3K4,MET,PIK3R3,MAP3K12,RRAS2,GAB1,MAP2K2,MAP3K7,MRAS,MAP3K8,PRKD3,PRKCB"]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis","1.96E00","1.31E-01","PTPN6,PPP1R12C,DUSP8,PTPN13,DOT1L,MDP1,PPTC7,PPIP5K1,NUDT2,PPM1K,PTPRM,DUSP2,TNS3,PPP1R16B,PPP1R12A,PPM1F,PALD1,DUSP16"]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis","1.96E00","1.31E-01","PTPN6,PPP1R12C,DUSP8,PTPN13,DOT1L,MDP1,PPTC7,PPIP5K1,NUDT2,PPM1K,PTPRM,DUSP2,TNS3,PPP1R16B,PPP1R12A,PPM1F,PALD1,DUSP16"]
["Nur77 Signaling in T Lymphocytes","1.96E00","1.67E-01","CD3G,HLA-DMA,CASP3,SIN3B,HLA-DQA1,NR4A1,HLA-DRB1,HLA-DQB1,HLA-DRB5,CABIN1"]
["Huntington's Disease Signaling","1.95E00","1.19E-01","PIK3CA,HSPA1A/HSPA1B,HDAC10,HSPA1L,HSPA4,SHC1,ARFIP2,POLR2A,SP1,TCERG1,NCOR1,PRKD3,DNM2,EGFR,TP53,POLR2J2/POLR2J3,SDHA,MAP2K7,PIK3C2A,CASP3,GLS,ITPR1,HDAC5,PIK3R3,PLCB3,CAPN9,NCOR2,UBC,PRKCB"]
["Erythropoietin Signaling","1.93E00","1.52E-01","PIK3R3,SHC1,PIK3CA,PTPN6,RRAS2,MAP2K2,PIK3C2A,MRAS,KRAS,JAK2,PRKD3,PRKCB"]
["Synaptic Long Term Depression","1.91E00","1.32E-01","PNPLA8,GNA12,PLA2G10,PLA2G4C,KRAS,ITPR1,NOS3,PPP2R1A,RRAS2,PRKG1,MAP2K2,NPR1,MRAS,PLCB3,PPP2R5C,PLA2G4F,GNA13,PRKD3,PPP2R1B,PRKCB"]
["Epithelial Adherens Junction Signaling","1.9E00","1.38E-01","DLL1,NOTCH3,LMO7,TGFBR3,KRAS,PTPRM,APC,MET,NOTCH2,NOTCH4,WASL,TUBA1A,RRAS2,KEAP1,MRAS,MYH9,CTNNB1,NOTCH1,ACTN1,EGFR,CTNND1"]
["Endometrial Cancer Signaling","1.9E00","1.67E-01","PIK3R3,TP53,PIK3CA,RRAS2,MAP2K2,PIK3C2A,MRAS,KRAS,GSK3B,CTNNB1"]
["Cholecystokinin/Gastrin-mediated Signaling","1.88E00","1.51E-01","GNA12,RHOJ,KRAS,ITPR1,SHC1,RRAS2,MAP2K2,RHOT1,IL1RN,MRAS,IL1B,PLCB3,GNA13,PRKD3,EGFR,PRKCB"]
["Renal Cell Carcinoma Signaling","1.83E00","1.54E-01","VEGFA,MET,PIK3R3,PIK3CA,RRAS2,MAP2K2,GAB1,PIK3C2A,CUL2,MRAS,KRAS,UBC"]
["IL-15 Signaling","1.83E00","1.53E-01","PIK3R3,SHC1,PIK3CA,JAK1,RRAS2,MAP2K2,PIK3C2A,TYK2,MRAS,KRAS,JAK2"]
["Eicosanoid Signaling","1.83E00","1.31E-01","PNPLA8,ALOX15,LTB4R2,PLA2G10,PLA2G4C,FPR2,PLA2G4F,ALOX5,GGT1,PTGER4,DPEP2"]
["CCR3 Signaling in Eosinophils","1.76E00","1.29E-01","PIK3CA,PIK3C2A,PLA2G10,PLA2G4C,MYLK,KRAS,ITPR1,PIK3R3,RRAS2,MAP2K2,MRAS,PPP1R12B,PLCB3,PPP1R12A,PLA2G4F,PRKD3,PRKCB"]
["T Cell Receptor Signaling","1.75E00","1.39E-01","FYN,PIK3CA,PIK3C2A,NFATC3,KRAS,CD8A,CD8B,PIK3R3,SHB,CD3G,NFAT5,RRAS2,MAP2K2,PAG1,MRAS"]
["Signaling by Rho Family GTPases","1.73E00","1.13E-01","PIK3CA,PPP1R12C,MYLK,ARFIP2,WASL,MAP2K2,RHOT1,MRAS,CDC42EP1,ARHGEF11,GNA13,CDH13,ITGA4,SEPT5,MAP2K7,PIK3C2A,ARHGEF15,GNA12,ITGA5,ARHGEF17,RHOJ,SEPT1,PIK3R3,MAP3K12,CDH5,ARHGEF6,PPP1R12B,PPP1R12A,ARHGEF10,PIP4K2A"]
["Regulation of Cellular Mechanics by Calpain Protease","1.73E00","1.41E-01","RRAS2,MRAS,ITGA5,KRAS,CAPN9,CAST,CDK1,ACTN1,ITGA4,EGFR"]
["IGF-1 Signaling","1.71E00","1.4E-01","PIK3CA,JAK1,PIK3C2A,SOCS2,KRAS,JAK2,IGFBP2,GRB10,PIK3R3,SHC1,RRAS2,MAP2K2,RPS6KB2,MRAS,IRS2"]
["Neuroprotective Role of THOP1 in Alzheimer's Disease","1.71E00","1.45E-01","HLA-G,MME,HLA-A,HLA-C,HLA-B,ECE1,HLA-F,HLA-E"]
["IL-17 Signaling","1.69E00","1.6E-01","PIK3R3,PIK3CA,MUC5B,JAK1,RRAS2,MAP2K2,PIK3C2A,MAP3K7,MRAS,KRAS,JAK2,GSK3B"]
["eNOS Signaling","1.69E00","1.22E-01","PIK3CA,PIK3C2A,CASP3,HSPA1A/HSPA1B,ADCY4,FLT1,FLT4,ITPR1,NOS3,HSPA1L,VEGFA,PIK3R3,HSPA4,ADCY9,PRKG1,FIGF,ADCY7,DNM2"]
["Regulation of the Epithelial-Mesenchymal Transition Pathway","1.68E00","1.24E-01","PIK3CA,MAP2K7,JAK1,JAG2,PIK3C2A,TYK2,FGFR2,NCSTN,KRAS,JAK2,APC,MET,PIK3R3,BRAF,RRAS2,FZD4,MAP2K2,GAB1,MRAS,DVL2,GSK3B,NOTCH1,EGFR,PDGFRB"]
["Glioma Invasiveness Signaling","1.63E00","1.54E-01","PIK3R3,PIK3CA,RRAS2,PIK3C2A,RHOT1,ITGAV,MRAS,RHOJ,KRAS,ITGB5"]
["Systemic Lupus Erythematosus Signaling","1.63E00","1.12E-01","FCGR2C,PIK3CA,NFATC3,HLA-A,PRPF39,KRAS,FCGR1A,HLA-G,LSM14A,NFAT5,PRPF4B,MRAS,PRPF40A,PRPF40B,HLA-F,PTPN6,PIK3C2A,HLA-B,PIK3R3,CD3G,RRAS2,HLA-C,IL1RN,SNRNP200,SF3B4,IL1B,HLA-E"]
["Communication between Innate and Adaptive Immune Cells","1.63E00","1.27E-01","HLA-A,HLA-B,HLA-DRB1,CD8A,CD8B,HLA-G,HLA-C,IL1RN,IL1B,HLA-F,CCL15,HLA-E,HLA-DRB5"]
["RhoGDI Signaling","1.61E00","1.15E-01","PPP1R12C,GNA12,ARHGEF15,ITGA5,RHOJ,ARHGEF17,ARHGAP5,WASL,CDH5,ARHGAP9,RHOT1,ARHGEF6,MRAS,PPP1R12B,PPP1R12A,ARHGAP12,ARHGEF11,WASF2,GNA13,PIP4K2A,ARHGEF10,CDH13,ITGA4"]
["Actin Cytoskeleton Signaling","1.6E00","1.13E-01","PIK3CA,FN1,TRIO,MYLK,KRAS,SHC1,WASL,MAP2K2,FLNA,MRAS,GNA13,ARHGAP24,ACTN1,ITGA4,PIK3C2A,GNA12,ITGA5,GSN,APC,PIK3R3,RRAS2,ARHGEF6,PPP1R12B,MYH9,PPP1R12A,WASF2,PIP4K2A"]
["Glioblastoma Multiforme Signaling","1.6E00","1.2E-01","TP53,PIK3CA,PIK3C2A,RHOJ,KRAS,ITPR1,APC,PIK3R3,SHC1,FZD4,RRAS2,MAP2K2,NF1,RHOT1,MRAS,PLCB3,GSK3B,CTNNB1,EGFR,PDGFRB"]
["Role of MAPK Signaling in the Pathogenesis of Influenza","1.59E00","1.57E-01","PNPLA8,MAP2K7,RRAS2,CASP3,MAP2K2,PLA2G10,PLA2G4C,MRAS,PLA2G4F,KRAS,RABGEF1"]
["GNRH Signaling","1.59E00","1.23E-01","MAP2K7,ADCY4,KRAS,MAP3K4,ITPR1,ADCY9,MAP3K12,RRAS2,MAP2K2,MAP3K7,MRAS,PLCB3,MAP3K8,ADCY7,PRKD3,DNM2,EGFR,PRKCB"]
["IL-8 Signaling","1.57E00","1.09E-01","PIK3CA,PIK3C2A,FLT1,GNA12,FLT4,RHOJ,KRAS,BRAF,PIK3R3,VEGFA,RRAS2,MAP2K2,CCND3,RHOT1,MRAS,ITGAV,FIGF,GNA13,PRKD3,MAP4K4,ITGB5,TEK,EGFR,PRKCB"]
["Leukotriene Biosynthesis","1.56E00","1.6E-01","MGST2,ALOX5,GGT1,DPEP2"]
["γ-glutamyl Cycle","1.56E00","1.48E-01","GGCT,GCLC,GGT1,ANPEP"]
["Agrin Interactions at Neuromuscular Junction","1.55E00","1.59E-01","RRAS2,ARHGEF6,LAMA2,LAMB1,MRAS,ITGA6,ITGA5,ITGA1,KRAS,ITGA4,EGFR"]
["RhoA Signaling","1.53E00","1.36E-01","PLXNA1,SEPT5,GNA12,RAPGEF6,MYLK,SEPT1,ARHGAP5,RAPGEF2,ARHGAP9,PPP1R12B,ARHGAP12,PPP1R12A,CDC42EP1,ARHGEF11,GNA13,SEMA3F,PIP4K2A"]
["HER-2 Signaling in Breast Cancer","1.53E00","1.46E-01","PIK3R3,TP53,PIK3CA,RRAS2,PIK3C2A,MRAS,KRAS,GSK3B,PRKD3,ITGB5,EGFR,PRKCB"]
["Role of NFAT in Cardiac Hypertrophy","1.51E00","1.16E-01","MAP2K7,PIK3CA,PIK3C2A,ADCY4,CSNK1A1,HDAC10,KRAS,ITPR1,CABIN1,HDAC5,PIK3R3,SHC1,ADCY9,RRAS2,MAP2K2,MAP3K7,MRAS,PLCB3,GSK3B,SLC8A1,ADCY7,PRKD3,PRKCB"]
["ErbB Signaling","1.51E00","1.44E-01","PIK3CA,PIK3C2A,KRAS,NCK2,PIK3R3,SHC1,RRAS2,MAP2K2,MRAS,GSK3B,PRKD3,PRKCB,EGFR"]
["Growth Hormone Signaling","1.51E00","1.43E-01","PIK3R3,PIK3CA,PTPN6,PIK3C2A,SOCS2,RPS6KB2,RPS6KA4,JAK2,STAT1,PRKD3,PRKCB"]
["GDNF Family Ligand-Receptor Interactions","1.51E00","1.45E-01","PIK3R3,SHC1,PIK3CA,RRAS2,MAP2K2,GAB1,PIK3C2A,MRAS,IRS2,KRAS,ITPR1"]
["Antiproliferative Role of Somatostatin Receptor 2","1.49E00","1.47E-01","PIK3R3,BRAF,PIK3CA,PTPN6,RRAS2,MAP2K2,PIK3C2A,NPR1,MRAS,KRAS"]
["Ovarian Cancer Signaling","1.47E00","1.2E-01","TP53,PIK3CA,PIK3C2A,KRAS,APC,BRAF,VEGFA,PIK3R3,FZD4,RRAS2,MAP2K2,RPS6KB2,MRAS,MSH6,FIGF,GSK3B,CTNNB1,EGFR"]
["NF-κB Signaling","1.45E00","1.24E-01","PIK3CA,MAP2K7,PIK3C2A,TGFBR3,FLT1,FLT4,FGFR2,KRAS,DDR1,BRAF,PIK3R3,RRAS2,MAP3K7,IL1RN,MRAS,IL1B,MAP3K8,GSK3B,MAP4K4,EGFR,PDGFRB,PRKCB"]
["Factors Promoting Cardiogenesis in Vertebrates","1.44E00","1.35E-01","TGFBR3,LRP6,BMP5,APC,FZD4,MAP3K7,GSK3B,BMP6,CTNNB1,PRKD3,LRP1,PRKCB,BMP1"]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages","1.44E00","1.08E-01","PTPN6,PIK3CA,MAP2K7,JAK1,PIK3C2A,TYK2,RHOJ,ARG2,MAP3K4,JAK2,PIK3R3,MAP3K12,PPP2R1A,MAP3K7,RHOT1,PPP1R12A,PPP2R5C,MAP3K8,STAT1,PPP1CA,PRKD3,PPP2R1B,PRKCB"]
["IL-2 Signaling","1.43E00","1.48E-01","PIK3R3,SHC1,PIK3CA,JAK1,RRAS2,MAP2K2,PIK3C2A,MRAS,KRAS"]
["CXCR4 Signaling","1.43E00","1.16E-01","PIK3CA,PIK3C2A,ADCY4,GNA12,RHOJ,KRAS,ITPR1,PIK3R3,ADCY9,RRAS2,MAP2K2,RHOT1,MRAS,PLCB3,ARHGEF11,GNA13,ELMO2,ADCY7,PRKD3,PRKCB"]
["MSP-RON Signaling Pathway","1.42E00","1.57E-01","PIK3R3,CSF2RB,PIK3CA,IL3RA,PIK3C2A,MST1,JAK2,MST1R"]
["Glucocorticoid Receptor Signaling","1.4E00","1.05E-01","PIK3CA,JAK1,HSPA1A/HSPA1B,NFATC3,KRAS,JAK2,FCGR1A,HSPA1L,SMARCA4,HSPA4,SHC1,POLR2A,NFAT5,MAP2K2,MAP3K7,MRAS,NCOR1,CDKN1C,STAT1,POLR2J2/POLR2J3,MAP2K7,TAF6,PIK3C2A,MED14,PIK3R3,CD3G,RRAS2,VIPR1,IL1RN,IL1B,NCOR2"]
["Mitotic Roles of Polo-Like Kinase","1.4E00","1.47E-01","SMC3,PPP2R1A,ANAPC5,PPP2R5C,PPP2R1B,ANAPC1,CDK1,STAG2,CDC27,SMC1A"]
["Pancreatic Adenocarcinoma Signaling","1.4E00","1.18E-01","PIK3R3,VEGFA,TP53,PIK3CA,RALA,JAK1,MAP2K2,PIK3C2A,TYK2,FIGF,KRAS,JAK2,STAT1,NOTCH1,EGFR"]
["Ephrin Receptor Signaling","1.38E00","1.06E-01","FYN,RGS3,ITSN1,EPHB2,PTPN13,GNA12,ARHGEF15,ITGA5,KRAS,JAK2,VEGFA,NCK2,SHC1,WASL,RRAS2,MAP2K2,ABI1,MRAS,FIGF,GNA13,MAP4K4,ITGA4"]
["IL-6 Signaling","1.37E00","1.29E-01","PIK3CA,MAP2K7,PIK3C2A,HSPB2,KRAS,JAK2,PIK3R3,VEGFA,SHC1,RRAS2,MAP2K2,MAP3K7,IL1RN,MRAS,IL1B,MAP4K4"]
["ERK5 Signaling","1.36E00","1.49E-01","RRAS2,GAB1,GNA12,MRAS,RPS6KB2,KRAS,RPS6KA4,MAP3K8,GNA13,EGFR"]
["Mismatch Repair in Eukaryotes","1.36E00","1.67E-01","MSH3,MSH6,SLC19A1,RFC1"]
["Sphingosine-1-phosphate Signaling","1.34E00","1.24E-01","PIK3R3,ADCY9,PIK3CA,CASP3,PIK3C2A,RHOT1,GNA12,ADCY4,SPHK1,PLCB3,RHOJ,SMPD1,GNA13,ADCY7,PDGFRB"]
["PPAR Signaling","1.34E00","1.26E-01","PPARG,SHC1,RRAS2,MAP2K2,MAP3K7,IL1RN,MRAS,IL1B,NCOR1,KRAS,NCOR2,MAP4K4,PDGFRB"]
["IL-17A Signaling in Airway Cells","1.32E00","1.32E-01","PIK3R3,PIK3CA,MUC5B,JAK1,MAP2K2,PIK3C2A,MAP3K7,TYK2,JAK2,GSK3B"]
["Docosahexaenoic Acid (DHA) Signaling","1.32E00","1.4E-01","PIK3R3,ALOX15,PIK3CA,CASP3,PIK3C2A,IL1B,GSK3B"]
["p70S6K Signaling","1.32E00","1.23E-01","PIK3CA,JAK1,PIK3C2A,KRAS,PIK3R3,SHC1,PPP2R1A,RRAS2,MAP2K2,MRAS,PLCB3,PPP2R5C,PRKD3,PPP2R1B,EGFR,PRKCB"]
["Fc Epsilon RI Signaling","1.31E00","1.28E-01","FYN,PIK3CA,MAP2K7,PIK3C2A,PLA2G10,PLA2G4C,KRAS,PIK3R3,RRAS2,GAB1,MAP2K2,MRAS,PLA2G4F,PRKD3,PRKCB"]
["HIF1α Signaling","1.31E00","1.28E-01","PIK3R3,VEGFA,TP53,PIK3CA,RRAS2,PIK3C2A,MMP28,CUL2,MRAS,FIGF,KRAS,NOS3,LDHA,MMP19"]
["EGF Signaling","1.3E00","1.41E-01","PIK3R3,SHC1,PIK3CA,MAP2K7,JAK1,PIK3C2A,ITPR1,STAT1,EGFR"]
["Role of JAK1, JAK2 and TYK2 in Interferon Signaling","1.29E00","1.79E-01","PTPN6,JAK1,TYK2,JAK2,STAT1"]
["Angiopoietin Signaling","1.28E00","1.33E-01","PIK3R3,ANGPTL1,PIK3CA,RRAS2,PIK3C2A,MRAS,KRAS,NOS3,TEK,TIE1"]
["Non-Small Cell Lung Cancer Signaling","1.28E00","1.2E-01","PIK3R3,TP53,PIK3CA,RRAS2,MAP2K2,PIK3C2A,MRAS,KRAS,ITPR1,EGFR"]
["Inhibition of Angiogenesis by TSP1","1.27E00","1.5E-01","VEGFA,HSPG2,TP53,FYN,CASP3,NOS3"]
["FcγRIIB Signaling in B Lymphocytes","1.22E00","1.17E-01","PIK3R3,SHC1,PIK3CA,RRAS2,PIK3C2A,MRAS,KRAS"]
["Myc Mediated Apoptosis Signaling","1.22E00","1.43E-01","PIK3R3,TP53,SHC1,PIK3CA,RRAS2,CASP3,PIK3C2A,MRAS,KRAS"]
["Glioma Signaling","1.21E00","1.16E-01","TP53,PIK3CA,PIK3C2A,KRAS,PIK3R3,SHC1,RRAS2,MAP2K2,MRAS,PRKD3,PRKCB,PDGFRB,EGFR"]
["Neurotrophin/TRK Signaling","1.21E00","1.33E-01","PIK3R3,SHC1,PIK3CA,MAP2K7,RRAS2,MAP2K2,GAB1,PIK3C2A,MRAS,KRAS"]
["TR/RXR Activation","1.21E00","1.1E-01","PIK3R3,KLF9,F10,PIK3CA,AKR1C1/AKR1C2,UCP2,ADRB1,PIK3C2A,NCOR1,ACACA,NCOR2,NRGN"]
["Dendritic Cell Maturation","1.21E00","1.04E-01","HLA-DMA,FCGR2C,PIK3CA,PIK3C2A,LEPR,HLA-A,HLA-B,HLA-DQA1,HLA-DRB1,JAK2,HLA-DQB1,FCGR1A,DDR1,PIK3R3,COL5A3,HLA-C,IL1RN,PLCB3,IL1B,STAT1,HLA-DRB5"]
["CMP-N-acetylneuraminate Biosynthesis I (Eukaryotes)","1.2E00","1.11E-01","GNE,CMAS"]
["GDP-glucose Biosynthesis","1.2E00","1.25E-01","PGM5,PGM2"]
["CD28 Signaling in T Helper Cells","1.2E00","1.13E-01","HLA-DMA,FYN,PIK3CA,PTPN6,PIK3C2A,NFATC3,HLA-DQA1,HLA-DRB1,HLA-DQB1,ITPR1,PIK3R3,CD3G,NFAT5,MAP2K2,HLA-DRB5"]
["Sperm Motility","1.2E00","1.09E-01","PNPLA8,PDE2A,PLA2G10,PLA2G4C,CACNA1H,ITPR1,PDE4D,PRKG1,NPR1,MRAS,PLCB3,PLA2G4F,MST1R,PRKD3,PRKCB"]
["Neuregulin Signaling","1.17E00","1.18E-01","PIK3R3,SHC1,RRAS2,MAP2K2,MRAS,RPS6KB2,ITGA5,KRAS,PRKD3,ITGA4,EGFR,PRKCB"]
["Cyclins and Cell Cycle Regulation","1.17E00","1.18E-01","TP53,PPP2R1A,CCND3,CUL1,HDAC10,PPP2R5C,GSK3B,SKP1,PPP2R1B,CDK1,HDAC5"]
["CD27 Signaling in Lymphocytes","1.15E00","1.38E-01","MAP3K12,MAP2K7,CASP3,MAP2K2,MAP3K7,MAP3K8,MAP3K4,CD27"]
["Leukocyte Extravasation Signaling","1.13E00","1.12E-01","PIK3CA,PIK3C2A,MMP28,ITGA6,ITGA5,MAP3K4,SELPLG,PIK3R3,ARHGAP5,WASL,MAP2K2,CDH5,ARHGAP9,JAM3,ARHGAP12,ITGA1,CTNNB1,PRKD3,ACTN1,ITGA4,CTNND1,MMP19,PRKCB"]
["GADD45 Signaling","1.12E00","1.82E-01","TP53,CCND3,MAP3K4,CDK1"]
["Apoptosis Signaling","1.11E00","1.21E-01","TP53,MAP2K7,RRAS2,CASP3,MAP2K2,MRAS,KRAS,CAPN9,SPTAN1,NAIP,MAP4K4,CDK1"]
["fMLP Signaling in Neutrophils","1.11E00","1.08E-01","PIK3R3,PIK3CA,RRAS2,NFAT5,MAP2K2,PIK3C2A,NFATC3,MRAS,FPR2,PLCB3,KRAS,ITPR1,PRKD3,PRKCB"]
["Corticotropin Releasing Hormone Signaling","1.11E00","1.04E-01","ADCY4,PTCH1,ITPR1,NOS3,BRAF,VEGFA,ADCY9,MAP2K2,NPR1,NR4A1,JUND,ADCY7,PRKD3,PRKCB"]
["Basal Cell Carcinoma Signaling","1.1E00","1.33E-01","TP53,FZD4,PTCH1,DVL2,GSK3B,BMP6,CTNNB1,BMP5,APC,BMP1"]
["IL-15 Production","1.1E00","1.61E-01","JAK1,TYK2,JAK2,MST1R,STAT1"]
["p53 Signaling","1.1E00","1.15E-01","TP53,PRKDC,PIK3CA,PIK3C2A,JMY,PIK3R3,CCNK,GNL3,GSK3B,CTNNB1,PIDD,PML,HIPK2"]
["Crosstalk between Dendritic Cells and Natural Killer Cells","1.09E00","1.14E-01","HLA-G,CSF2RB,IL3RA,MICB,HLA-A,HLA-C,HLA-B,HLA-DRB1,HLA-F,MICA,HLA-DRB5,HLA-E"]
["Xenobiotic Metabolism Signaling","1.08E00","1.06E-01","PIK3CA,GCLC,KRAS,MAP3K4,GSTT2/GSTT2B,MAP2K2,MAP3K7,KEAP1,MRAS,PPP2R5C,PRKD3,ALDH7A1,MAP2K7,PIK3C2A,HDAC5,ESD,PIK3R3,MAP3K12,PPP2R1A,RRAS2,MGST2,IL1B,ALDH3B1,MAP3K8,NDST2,NCOR2,PPP2R1B,EIF2AK3,PRKCB"]
["Ceramide Signaling","1.08E00","1.21E-01","PIK3R3,PIK3CA,PPP2R1A,RRAS2,PIK3C2A,MRAS,SPHK1,PPP2R5C,KRAS,SMPD1,PPP2R1B"]
["FLT3 Signaling in Hematopoietic Progenitor Cells","1.07E00","1.33E-01","PIK3R3,SHC1,PIK3CA,RRAS2,MAP2K2,PIK3C2A,MRAS,KRAS,RPS6KA4,STAT1"]
["Wnt/β-catenin Signaling","1.06E00","1.17E-01","TP53,FRZB,TGFBR3,LRP6,CSNK1A1,KREMEN1,APC,PPP2R1A,FZD4,CDH5,MAP3K7,RUVBL2,PPP2R5C,SOX18,DVL2,GSK3B,UBC,CTNNB1,PPP2R1B,LRP1"]
["Glutamate Removal from Folates","1.06E00","3.33E-01","GGH"]
["Asparagine Biosynthesis I","1.06E00","1.25E-01","ASNS"]
["Lanosterol Biosynthesis","1.06E00","3.33E-01","LSS"]
["Sulfite Oxidation IV","1.06E00","2.5E-01","SUOX"]
["Natural Killer Cell Signaling","1.05E00","1.2E-01","FYN,PIK3CA,PTPN6,PIK3C2A,SH3BP2,KRAS,LILRB1,PIK3R3,SHC1,RRAS2,MAP2K2,MRAS,PRKD3,PRKCB"]
["Glucose and Glucose-1-phosphate Degradation","1.05E00","9.52E-02","PGM5,PGM2"]
["DNA Methylation and Transcriptional Repression Signaling","1.05E00","1.74E-01","CHD3,CHD4,DNMT1,ARID4B"]
["B Cell Development","1.05E00","1.56E-01","HLA-DMA,HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-DRB5"]
["Pyridoxal 5'-phosphate Salvage Pathway","1.04E00","1.23E-01","BRAF,DMPK,MAP2K2,PRPF4B,GRK6,CSNK1A1,MAP3K8,CDK1,DYRK1A"]
["Cell Cycle: G1/S Checkpoint Regulation","1.04E00","1.3E-01","TP53,CCND3,PAK1IP1,CUL1,HDAC10,GNL3,GSK3B,SKP1,HDAC5"]
["Dermatan Sulfate Degradation (Metazoa)","1.02E00","1.43E-01","IDS,HYAL1,HEXA"]
["LPS-stimulated MAPK Signaling","1.01E00","1.22E-01","PIK3R3,PIK3CA,RRAS2,MAP2K2,PIK3C2A,MAP3K7,MRAS,KRAS,PRKD3,PRKCB"]
["Leptin Signaling in Obesity","1.01E00","1.2E-01","PIK3R3,ADCY9,PIK3CA,MAP2K2,PIK3C2A,LEPR,ADCY4,PLCB3,JAK2,ADCY7"]
["Ephrin B Signaling","1.01E00","1.23E-01","NCK2,RGS3,ABI1,ITSN1,EPHB2,GNA12,MRAS,ITSN2,GNA13,CTNNB1"]
["Salvage Pathways of Pyrimidine Ribonucleotides","1E00","1.09E-01","BRAF,DMPK,MAP2K2,PRPF4B,UPP1,GRK6,CSNK1A1,MAP3K8,UCK2,CDK1,APOBEC3A,DYRK1A"]
["HMGB1 Signaling","9.76E-01","1.1E-01","PIK3R3,PIK3CA,MAP2K7,RRAS2,SP1,AGER,MAP2K2,PIK3C2A,RHOT1,MRAS,RHOJ,KRAS"]
["Cardiac β-adrenergic Signaling","9.71E-01","1.04E-01","AKAP12,PDE2A,ADCY4,PDE4D,AKAP11,ADCY9,PPP2R1A,ADRB1,MRAS,PPP1R12A,PPP2R5C,SLC8A1,PPP1CA,AKAP9,ADCY7,PPP2R1B"]
["iCOS-iCOSL Signaling in T Helper Cells","9.65E-01","1.07E-01","PIK3R3,CD3G,SHC1,HLA-DMA,PIK3CA,NFAT5,PIK3C2A,NFATC3,HLA-DQA1,HLA-DRB1,ITPR1,HLA-DQB1,HLA-DRB5"]
["Ethanol Degradation II","9.46E-01","1.25E-01","ADH1C,ADH1B,ADHFE1,ALDH7A1,DHRS4"]
["DNA Double-Strand Break Repair by Non-Homologous End Joining","9.39E-01","1.5E-01","PRKDC,LIG4,RAD50"]
["Superpathway of Citrulline Metabolism","9.39E-01","7.89E-02","GLS,ARG2,NOS3"]
["α-Adrenergic Signaling","9.35E-01","1.04E-01","ADCY9,RRAS2,MAP2K2,ADCY4,MRAS,KRAS,ITPR1,SLC8A1,PRKD3,ADCY7,PRKCB"]
["Polyamine Regulation in Colon Cancer","9.3E-01","1.33E-01","PPARG,KRAS,CTNNB1,APC"]
["Inositol Pyrophosphates Biosynthesis","9.29E-01","1.25E-01","PPIP5K1,IP6K2"]
["Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells","9E-01","1.35E-01","CD3G,CASP3,HLA-A,HLA-C,HLA-B"]
["Estrogen Receptor Signaling","8.89E-01","1.11E-01","POLR2J2/POLR2J3,PRKDC,TAF6,RBFOX2,KRAS,MED12,SMARCA4,MED14,SHC1,POLR2A,RRAS2,MAP2K2,MRAS,NCOR1,NCOR2"]
["IL-10 Signaling","8.8E-01","1.15E-01","FCGR2C,JAK1,SP1,IL1RN,MAP3K7,TYK2,IL1B,ARG2,MAP4K4"]
["Glutathione-mediated Detoxification","8.76E-01","1.03E-01","GSTT2/GSTT2B,MGST2,GGH,ANPEP"]
["Telomere Extension by Telomerase","8.69E-01","1.67E-01","HNRNPA1,TNKS2,RAD50"]
["G Beta Gamma Signaling","8.59E-01","9.48E-02","SHC1,RRAS2,GNA12,ARHGEF6,MRAS,KRAS,GNA13,PRKD3,DNM2,EGFR,PRKCB"]
["Noradrenaline and Adrenaline Degradation","8.57E-01","1.02E-01","ADH1C,ADH1B,ADHFE1,ALDH7A1,DHRS4"]
["CREB Signaling in Neurons","8.38E-01","9.64E-02","POLR2J2/POLR2J3,PIK3CA,PIK3C2A,ADCY4,GNA12,KRAS,ITPR1,PIK3R3,ADCY9,SHC1,POLR2A,RRAS2,MAP2K2,MRAS,PLCB3,GNA13,ADCY7,PRKD3,PRKCB"]
["Citrulline Biosynthesis","8.29E-01","7.69E-02","GLS,ARG2"]
["Ketolysis","8.29E-01","1.18E-01","ACAT2,OXCT1"]
["Prostate Cancer Signaling","8.16E-01","1E-01","PIK3R3,TP53,PIK3CA,RRAS2,MAP2K2,PIK3C2A,MRAS,KRAS,GSK3B,CTNNB1"]
["RAN Signaling","8.07E-01","1.3E-01","KPNB1,CSE1L,RANBP2"]
["Granzyme B Signaling","8.07E-01","1.67E-01","PRKDC,CASP3,NUMA1"]
["Extrinsic Prothrombin Activation Pathway","8.07E-01","1.36E-01","F10,F13A1,THBD"]
["PEDF Signaling","7.98E-01","1.14E-01","PPARG,PIK3R3,TP53,PIK3CA,RRAS2,PIK3C2A,MRAS,KRAS,WASF2"]
["Semaphorin Signaling in Neurons","7.94E-01","1.3E-01","MET,FYN,PLXNA1,FES,RHOT1,PLXNB1,RHOJ"]
["UVB-Induced MAPK Signaling","7.94E-01","1.23E-01","PIK3R3,TP53,PIK3CA,PIK3C2A,PRKD3,EGFR,PRKCB"]
["AMPK Signaling","7.9E-01","8.47E-02","PIK3CA,ACACB,PIK3C2A,LIPE,NOS3,SMARCA4,PPM1D,PIK3R3,PPP2R1A,ADRB1,MRAS,PPP2R5C,IRS2,ACACA,PPP2R1B"]
["Cell Cycle: G2/M DNA Damage Checkpoint Regulation","7.83E-01","1.25E-01","TOP2B,TP53,PRKDC,CUL1,SKP1,CDK1"]
["Estrogen-Dependent Breast Cancer Signaling","7.81E-01","1.11E-01","PIK3R3,PIK3CA,RRAS2,SP1,PIK3C2A,MRAS,KRAS,EGFR"]
["Choline Degradation I","7.8E-01","1.43E-01","ALDH7A1"]
["S-methyl-5-thio-α-D-ribose 1-phosphate Degradation","7.8E-01","6.67E-02","MRI1"]
["Flavin Biosynthesis IV (Mammalian)","7.8E-01","1.25E-01","FLAD1"]
["L-cysteine Degradation III","7.8E-01","1.11E-01","MPST"]
["Formaldehyde Oxidation II (Glutathione-dependent)","7.8E-01","1E-01","ESD"]
["Glutamine Degradation I","7.8E-01","2E-01","GLS"]
["Role of JAK family kinases in IL-6-type Cytokine Signaling","7.79E-01","1.43E-01","JAK1,TYK2,JAK2,STAT1"]
["Interferon Signaling","7.76E-01","1.39E-01","JAK1,TYK2,JAK2,STAT1,MED14"]
["Relaxin Signaling","7.71E-01","9.43E-02","PIK3R3,VEGFA,BRAF,ADCY9,PIK3CA,PDE2A,PIK3C2A,NPR1,GNA12,ADCY4,MRAS,GNA13,PDE4D,NOS3,ADCY7"]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis","7.66E-01","9.43E-02","PIK3CA,MAP2K7,PIK3C2A,FRZB,NFATC3,LRP6,CSNK1A1,ITGA5,GSN,BMP5,NAIP,APC,PIK3R3,NFAT5,FZD4,MAP3K7,IL1RN,IL1B,GSK3B,BMP6,CTNNB1,LRP1,BMP1"]
["Chronic Myeloid Leukemia Signaling","7.66E-01","1.06E-01","PIK3R3,TP53,PIK3CA,RRAS2,MAP2K2,MECOM,PIK3C2A,MRAS,HDAC10,KRAS,HDAC5"]
["Tec Kinase Signaling","7.45E-01","9.34E-02","FYN,PIK3CA,JAK1,PIK3C2A,GNA12,TYK2,ITGA5,RHOJ,JAK2,PIK3R3,RHOT1,MRAS,GNA13,STAT1,PRKD3,ITGA4,PRKCB"]
["Glycogen Degradation II","7.45E-01","1.33E-01","PGM5,PGM2"]
["Rac Signaling","7.45E-01","9.45E-02","PIK3R3,PIK3CA,MAP2K7,ARFIP2,RRAS2,MAP2K2,PIK3C2A,MRAS,ITGA5,KRAS,PIP4K2A,ITGA4"]
["BMP signaling pathway","7.23E-01","1.08E-01","SOSTDC1,RRAS2,MAP2K2,MAP3K7,MRAS,KRAS,BMP6,BMP5,BMP1"]
["Endoplasmic Reticulum Stress Pathway","6.97E-01","1.58E-01","CASP3,ERN1,EIF2AK3"]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation","6.84E-01","9.8E-02","FN1,EDNRB,LEPR,FLT1,FLT4,FGFR2,VEGFA,MET,IL1B,FIGF,MYH9,ECE1,STAT1,EGFR,PDGFRB"]
["Bladder Cancer Signaling","6.79E-01","1.06E-01","VEGFA,TP53,RRAS2,MMP28,MAP2K2,MRAS,FIGF,KRAS,EGFR,MMP19"]
["RANK Signaling in Osteoclasts","6.79E-01","1.04E-01","PIK3R3,MAP3K12,PIK3CA,MAP2K7,MAP2K2,PIK3C2A,MAP3K7,MAP3K8,MAP3K4,GSN"]
["Remodeling of Epithelial Adherens Junctions","6.77E-01","1.18E-01","MET,RALA,TUBA1A,CTNNB1,ACTN1,APC,DNM2,CTNND1"]
["Gα12/13 Signaling","6.72E-01","1.03E-01","PIK3R3,MAP2K7,PIK3CA,RRAS2,CDH5,MAP2K2,PIK3C2A,GNA12,MRAS,KRAS,GNA13,CTNNB1,CDH13"]
["G-Protein Coupled Receptor Signaling","6.72E-01","9.56E-02","FYN,PDE2A,PIK3CA,PIK3C2A,NPY1R,DUSP6,ADCY4,FPR2,KRAS,PDE4D,CHRM3,PIK3R3,BRAF,ADCY9,SHC1,RRAS2,GPER1,ADRB1,VIPR1,MAP2K2,MRAS,PLCB3,MAP3K8,ADCY7,PTGER4,PRKCB"]
["Intrinsic Prothrombin Activation Pathway","6.56E-01","1.11E-01","F10,COL5A3,F13A1,THBD"]
["P2Y Purigenic Receptor Signaling Pathway","6.55E-01","9.29E-02","PIK3R3,ADCY9,PIK3CA,RRAS2,MAP2K2,PIK3C2A,ADCY4,MRAS,PLCB3,KRAS,ADCY7,PRKD3,PRKCB"]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis","6.51E-01","8.95E-02","PIK3CA,FN1,FRZB,NFATC3,LRP6,CSNK1A1,KRAS,JAK2,FCGR1A,VEGFA,NFAT5,MAP2K2,MAP3K7,MRAS,FIGF,GSK3B,CTNNB1,PRKD3,MAP2K7,PIK3C2A,APC,PIK3R3,FZD4,RRAS2,IL1RN,PLCB3,IL1B,LRP1,PRKCB"]
["DNA damage-induced 14-3-3σ Signaling","6.49E-01","1.36E-01","TP53,RAD17,CDK1"]
["Gαs Signaling","6.49E-01","9.92E-02","BRAF,ADCY9,GPER1,RAPGEF2,ADRB1,MAP2K2,VIPR1,ADCY4,MRAS,ADCY7,CHRM3,PTGER4"]
["tRNA Charging","6.39E-01","6.17E-02","YARS,LARS2,DARS2,SARS,VARS"]
["Inhibition of Matrix Metalloproteases","6.39E-01","1.28E-01","HSPG2,MMP28,RECK,LRP1,MMP19"]
["Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes","6.34E-01","1.02E-01","FYN,CD3G,MAP2K7,NFAT5,RRAS2,MAP2K2,NFATC3,MRAS,KRAS"]
["Chemokine Signaling","6.31E-01","1.08E-01","RRAS2,MAP2K2,MRAS,PPP1R12B,PPP1R12A,PLCB3,KRAS,PRKCB"]
["Glutathione Biosynthesis","6.23E-01","9.09E-02","GCLC"]
["Oxidized GTP and dGTP Detoxification","6.23E-01","9.09E-02","RUVBL2"]
["Glutamate Degradation II","6.23E-01","1E-01","GOT2"]
["Aspartate Biosynthesis","6.23E-01","1.43E-01","GOT2"]
["Sonic Hedgehog Signaling","6.2E-01","1.18E-01","PTCH1,GSK3B,CDK1,DYRK1A"]
["IL-12 Signaling and Production in Macrophages","6.12E-01","9.09E-02","PIK3R3,PPARG,JMJD6,ALOX15,PIK3CA,MAP2K2,PIK3C2A,IL12RB1,MST1,MAP3K8,MST1R,STAT1,PRKD3,PRKCB"]
["Glycogen Degradation III","6.09E-01","1.18E-01","PGM5,PGM2"]
["ATM Signaling","6.06E-01","1.08E-01","TP53,SMC3,TP53BP1,TLK2,CDK1,RAD50,SMC1A"]
["Human Embryonic Stem Cell Pluripotency","5.97E-01","8.86E-02","PIK3CA,PIK3C2A,FGFR2,BMP5,APC,PIK3R3,FZD4,MRAS,SPHK1,GSK3B,BMP6,CTNNB1,BMP1,PDGFRB"]
["Role of p14/p19ARF in Tumor Suppression","5.86E-01","1.14E-01","PIK3R3,TP53,PIK3CA,PIK3C2A"]
["Role of BRCA1 in DNA Damage Response","5.82E-01","9.86E-02","TP53,MSH6,SLC19A1,RFC1,STAT1,RAD50,SMARCA4"]
["Role of PKR in Interferon Induction and Antiviral Response","5.8E-01","1.04E-01","TP53,CASP3,MAP3K7,STAT1,FCGR1A"]
["Cardiac Hypertrophy Signaling","5.78E-01","9.05E-02","PIK3CA,MAP2K7,PIK3C2A,ADCY4,GNA12,RHOJ,KRAS,MAP3K4,PIK3R3,ADCY9,MAP3K12,RRAS2,ADRB1,MAP2K2,MAP3K7,RHOT1,MRAS,PLCB3,MAP3K8,GNA13,GSK3B,ADCY7"]
["PI3K Signaling in B Lymphocytes","5.73E-01","9.42E-02","FYN,PIK3CA,RRAS2,NFAT5,MAP2K2,NFATC3,MRAS,PLCB3,IRS2,PIK3AP1,KRAS,ITPR1,PRKCB"]
["Cellular Effects of Sildenafil (Viagra)","5.57E-01","8.72E-02","ADCY9,PDE2A,PRKG1,ADCY4,PPP1R12B,PLCB3,PPP1R12A,MYH9,MYLK,ITPR1,PDE4D,NOS3,ADCY7"]
["Chondroitin Sulfate Degradation (Metazoa)","5.54E-01","9.52E-02","HYAL1,HEXA"]
["Type II Diabetes Mellitus Signaling","5.48E-01","7.27E-02","PPARG,PIK3R3,PIK3CA,MAP2K7,PIK3C2A,MAP3K7,PKM,SOCS2,IRS2,SMPD1,PRKD3,PRKCB"]
["Dopamine-DARPP32 Feedback in cAMP Signaling","5.45E-01","8.89E-02","KCNJ8,ADCY4,CSNK1A1,ITPR1,ADCY9,PPP2R1A,PRKG1,PPP1R12A,PLCB3,PPP2R5C,PPP1CA,ADCY7,PRKD3,PPP2R1B,CAMKK2,PRKCB"]
["14-3-3-mediated Signaling","5.18E-01","1E-01","PIK3R3,PIK3CA,RRAS2,TUBA1A,MAP2K2,PIK3C2A,MRAS,PLCB3,KRAS,GSK3B,PRKD3,PRKCB"]
["Heme Degradation","5.17E-01","9.09E-02","HMOX2"]
["Serine Biosynthesis","5.17E-01","7.69E-02","PSPH"]
["Heme Biosynthesis from Uroporphyrinogen-III I","5.17E-01","9.09E-02","PPOX"]
["Geranylgeranyldiphosphate Biosynthesis","5.17E-01","1.25E-01","FDPS"]
["Arginine Degradation I (Arginase Pathway)","5.17E-01","7.69E-02","ARG2"]
["Trans, trans-farnesyl Diphosphate Biosynthesis","5.17E-01","1.11E-01","FDPS"]
["L-cysteine Degradation I","5.17E-01","9.09E-02","GOT2"]
["Assembly of RNA Polymerase III Complex","5.05E-01","1.25E-01","GTF3C1,BDP1"]
["Urate Biosynthesis/Inosine 5'-phosphate Degradation","5.05E-01","9.09E-02","IMPDH1,AOX1"]
["Bile Acid Biosynthesis, Neutral Pathway","5.05E-01","3.45E-02","AMACR,AKR1C1/AKR1C2"]
["mTOR Signaling","4.92E-01","8.82E-02","PIK3CA,PIK3C2A,RHOJ,KRAS,VEGFA,PIK3R3,PPP2R1A,RRAS2,RHOT1,EIF4A1,MRAS,RPS6KB2,FIGF,RPS6KA4,PPP2R5C,PRKD3,PPP2R1B,PRKCB"]
["Dopamine Receptor Signaling","4.9E-01","8.42E-02","ADCY9,PPP2R1A,ADCY4,PPP1R12A,PPP2R5C,PPP1CA,PPP2R1B,ADCY7"]
["DNA Double-Strand Break Repair by Homologous Recombination","4.62E-01","1.11E-01","ATRX,RAD50"]
["Isoleucine Degradation I","4.62E-01","6.9E-02","BCAT1,ACAT2"]
["IL-22 Signaling","4.61E-01","1.2E-01","JAK1,TYK2,STAT1"]
["Atherosclerosis Signaling","4.61E-01","8.82E-02","PNPLA8,ALOX15,COL5A3,IL1RN,PLA2G10,PLA2G4C,IL1B,PLA2G4F,ALOX5,TPSAB1/TPSB2,ITGA4,SELPLG"]
["Regulation of eIF4 and p70S6K Signaling","4.47E-01","8.28E-02","PIK3R3,SHC1,PPP2R1A,PIK3CA,RRAS2,MAP2K2,PIK3C2A,EIF4A1,MRAS,ITGA5,PPP2R5C,KRAS,PPP2R1B,ITGA4"]
["T Helper Cell Differentiation","4.43E-01","1E-01","HLA-DMA,IL12RB1,HLA-DQA1,HLA-DRB1,HLA-DQB1,STAT1,HLA-DRB5"]
["Pyruvate Fermentation to Lactate","4.38E-01","1.11E-01","LDHA"]
["Lysine Degradation II","4.38E-01","5.26E-02","ALDH7A1"]
["Lysine Degradation V","4.38E-01","3.57E-02","ALDH7A1"]
["Citrulline-Nitric Oxide Cycle","4.38E-01","6.25E-02","NOS3"]
["Aryl Hydrocarbon Receptor Signaling","4.35E-01","7.93E-02","TP53,GSTT2/GSTT2B,TRIP11,NCOA7,CCND3,SP1,MGST2,HSPB2,IL1B,ALDH3B1,NCOR2,SMARCA4,ALDH7A1"]
["Primary Immunodeficiency Signaling","4.34E-01","8.77E-02","RFXANK,IGLL1/IGLL5,CIITA,CD8A,TAP2"]
["Gαq Signaling","4.24E-01","8.33E-02","PIK3CA,PIK3C2A,NFATC3,RHOJ,ITPR1,CHRM3,PIK3R3,MAP2K2,RHOT1,MRAS,PLCB3,GSK3B,PRKD3,PRKCB"]
["Acute Phase Response Signaling","4.15E-01","8.89E-02","PIK3CA,MAP2K7,FN1,SOCS2,KRAS,JAK2,HMOX2,PIK3R3,SHC1,RRAS2,MAP2K2,MAP3K7,IL1RN,C4BPA,MRAS,IL1B"]
["Hepatic Cholestasis","4.11E-01","7.26E-02","ADCY9,TJP2,SLCO3A1,MAP3K7,IL1RN,PPRC1,ABCC1,ADCY4,IL1B,MAP3K4,ADCY7,PRKD3,PRKCB"]
["Superpathway of Geranylgeranyldiphosphate Biosynthesis I (via Mevalonate)","3.88E-01","5.88E-02","FDPS,ACAT2"]
["Parkinson's Signaling","3.88E-01","1.05E-01","SEPT5,CASP3"]
["Regulation of Actin-based Motility by Rho","3.79E-01","8.79E-02","WASL,RHOT1,PPP1R12B,PPP1R12A,RHOJ,MYLK,GSN,PIP4K2A"]
["Superpathway of Cholesterol Biosynthesis","3.78E-01","3.57E-02","FDPS,ACAT2,LSS"]
["Clathrin-mediated Endocytosis Signaling","3.78E-01","8.67E-02","MYO6,AP2M1,PIK3CA,PIK3C2A,EPHB2,GAK,NUMB,ITGA5,AP1B1,PIK3R3,VEGFA,MET,WASL,FIGF,UBC,ITGB5,DNM2"]
["Superpathway of Serine and Glycine Biosynthesis I","3.77E-01","5.56E-02","PSPH"]
["Urea Cycle","3.77E-01","5E-02","ARG2"]
["Chondroitin and Dermatan Biosynthesis","3.77E-01","7.69E-02","CHPF2"]
["Arginine Degradation VI (Arginase 2 Pathway)","3.77E-01","6.25E-02","ARG2"]
["Selenocysteine Biosynthesis II (Archaea and Eukaryotes)","3.77E-01","5.88E-02","SARS"]
["Purine Ribonucleosides Degradation to Ribose-1-phosphate","3.77E-01","5.56E-02","PGM2"]
["Pregnenolone Biosynthesis","3.77E-01","7.69E-02","MICAL3"]
["Aspartate Degradation II","3.77E-01","7.69E-02","GOT2"]
["RAR Activation","3.75E-01","8.42E-02","PIK3CA,IL3RA,ADCY4,ADH1C,JAK2,SMARCA4,VEGFA,PIK3R3,ADCY9,CSF2RB,NCOR1,NCOR2,PML,ADCY7,PRKD3,PRKCB"]
["p38 MAPK Signaling","3.73E-01","9.32E-02","TP53,IL1RN,MAP3K7,HSPB2,PLA2G10,PLA2G4C,RPS6KB2,IL1B,PLA2G4F,RPS6KA4,STAT1"]
["TREM1 Signaling","3.63E-01","8.05E-02","NLRP3,NLRP1,CIITA,ITGA5,IL1B,JAK2,NAIP"]
["Amyloid Processing","3.58E-01","8.33E-02","CSNK1A1,NCSTN,BACE1,CAPN9,GSK3B"]
["Glutathione Redox Reactions I","3.56E-01","8.33E-02","CLIC2,MGST2"]
["Netrin Signaling","3.56E-01","7.41E-02","NCK2,NFAT5,PRKG1,NFATC3"]
["CD40 Signaling","3.45E-01","8.57E-02","PIK3R3,PIK3CA,MAP2K7,MAP2K2,PIK3C2A,MAP3K7"]
["FGF Signaling","3.39E-01","8.6E-02","MET,PIK3R3,PIK3CA,PTPN6,GAB1,PIK3C2A,FGFR2,ITPR1"]
["Amyotrophic Lateral Sclerosis Signaling","3.31E-01","7.32E-02","VEGFA,PIK3R3,TP53,PIK3CA,CASP3,PIK3C2A,FIGF,CAPN9,NAIP"]
["Phosphatidylcholine Biosynthesis I","3.28E-01","5.88E-02","CHKA"]
["Tryptophan Degradation to 2-amino-3-carboxymuconate Semialdehyde","3.28E-01","5.88E-02","IDO1"]
["Purine Nucleotides Degradation II (Aerobic)","3.28E-01","5.71E-02","IMPDH1,AOX1"]
["Serotonin Degradation","3.25E-01","7.25E-02","ADH1C,ADH1B,ADHFE1,ALDH7A1,DHRS4"]
["MIF Regulation of Innate Immunity","3.19E-01","7.69E-02","TP53,PLA2G10,PLA2G4C,PLA2G4F"]
["TGF-β Signaling","3.14E-01","8.51E-02","ZFYVE9,RRAS2,MAP2K2,MAP3K7,MRAS,KRAS,TFE3,PMEPA1"]
["Androgen Signaling","3.14E-01","7.19E-02","POLR2J2/POLR2J3,SHC1,HSPA4,TGFB1I1,POLR2A,GNA12,MRAS,GNA13,PRKD3,PRKCB"]
["Cardiomyocyte Differentiation via BMP Receptors","3.02E-01","9.52E-02","MAP3K7,BMP5"]
["1D-myo-inositol Hexakisphosphate Biosynthesis II (Mammalian)","3.02E-01","7.14E-02","ITPKB,SEC16A"]
["D-myo-inositol (1,3,4)-trisphosphate Biosynthesis","3.02E-01","8E-02","ITPKB,SEC16A"]
["Tryptophan Degradation III (Eukaryotic)","3.02E-01","4.35E-02","ACAT2,IDO1"]
["G Protein Signaling Mediated by Tubby","2.92E-01","7.32E-02","MRAS,PLCB3,JAK2"]
["Superpathway of Methionine Degradation","2.92E-01","4.62E-02","AHCYL2,GOT2,SUOX"]
["Phosphatidylethanolamine Biosynthesis II","2.87E-01","5.56E-02","CHKA"]
["Salvage Pathways of Pyrimidine Deoxyribonucleotides","2.87E-01","5E-02","APOBEC3A"]
["Sphingomyelin Metabolism","2.87E-01","6.25E-02","SMPD1"]
["iNOS Signaling","2.85E-01","7.69E-02","JAK1,TYK2,JAK2,STAT1"]
["Phospholipases","2.81E-01","7.69E-02","PNPLA8,PLA2G10,PLA2G4C,PLCB3,PLA2G4F"]
["Role of Lipids/Lipid Rafts in the Pathogenesis of Influenza","2.78E-01","8E-02","FDPS,RSAD2"]
["Melatonin Signaling","2.77E-01","7.69E-02","BRAF,MAP2K7,MAP2K2,PLCB3,PRKD3,PRKCB"]
["IL-1 Signaling","2.7E-01","7.48E-02","ADCY9,MAP2K7,MAP3K7,ADCY4,GNA12,MRAS,GNA13,ADCY7"]
["MIF-mediated Glucocorticoid Regulation","2.57E-01","7.14E-02","PLA2G10,PLA2G4C,PLA2G4F"]
["Assembly of RNA Polymerase I Complex","2.54E-01","7.69E-02","POLR1D"]
["Leucine Degradation I","2.54E-01","3.85E-02","BCAT1"]
["Heme Biosynthesis II","2.54E-01","4.35E-02","PPOX"]
["Histidine Degradation VI","2.54E-01","5E-02","MICAL3"]
["Folate Transformations I","2.54E-01","3.12E-02","MTHFR"]
["GABA Receptor Signaling","2.42E-01","7.27E-02","AP2M1,GABARAP,AP1B1,UBC"]
["Ketogenesis","2.25E-01","5E-02","ACAT2"]
["NAD Phosphorylation and Dephosphorylation","2.25E-01","5.88E-02","NADK"]
["Methylglyoxal Degradation III","2.25E-01","5.88E-02","AKR1C1/AKR1C2"]
["Dolichyl-diphosphooligosaccharide Biosynthesis","2.25E-01","2.56E-02","ALG13"]
["Glutaryl-CoA Degradation","2E-01","4.35E-02","ACAT2"]
["Purine Nucleotides De Novo Biosynthesis II","2E-01","2.44E-02","IMPDH1"]