LEVEL1 LEVEL2 SUBSYSTEM_ID MDE1 MDE2 NCD1 NCD2 CREO1 CREO2 CRUST1 CRUST2 ORNL1 ORNL2 Amino Acids and Derivatives Alanine, serine, and glycine ss00145 88 77 54 48 61 106 60 92 71 60 Amino Acids and Derivatives Alanine, serine, and glycine ss00572 103 102 61 77 125 209 131 233 92 87 Amino Acids and Derivatives Alanine, serine, and glycine ss00628 327 316 156 205 313 549 317 591 251 233 Amino Acids and Derivatives Alanine, serine, and glycine ss00778 149 138 68 76 121 225 140 260 108 102 Amino Acids and Derivatives Alanine, serine, and glycine ss01070 234 218 96 120 135 239 144 251 147 126 Amino Acids and Derivatives Arginine; urea cycle, polyamines ss00056 393 356 195 224 211 429 256 515 337 284 Amino Acids and Derivatives Arginine; urea cycle, polyamines ss00317 87 65 44 49 88 167 110 220 52 45 Amino Acids and Derivatives Arginine; urea cycle, polyamines ss00406 270 256 133 181 208 353 240 428 250 186 Amino Acids and Derivatives Arginine; urea cycle, polyamines ss00502 667 572 318 338 508 878 526 923 494 394 Amino Acids and Derivatives Arginine; urea cycle, polyamines ss00662 26 28 16 14 23 39 22 45 29 20 Amino Acids and Derivatives Arginine; urea cycle, polyamines ss00759 50 40 25 29 50 77 42 76 47 32 Amino Acids and Derivatives Arginine; urea cycle, polyamines ss00829 324 328 220 271 226 399 201 398 303 266 Amino Acids and Derivatives Aromatic amino acids and derivatives ss00186 196 157 90 106 72 120 60 113 128 121 Amino Acids and Derivatives Aromatic amino acids and derivatives ss00188 296 239 121 139 197 337 205 340 174 147 Amino Acids and Derivatives Aromatic amino acids and derivatives ss00272 0 2 0 1 0 0 0 1 0 1 Amino Acids and Derivatives Aromatic amino acids and derivatives ss00391 127 113 57 60 92 173 100 186 101 90 Amino Acids and Derivatives Aromatic amino acids and derivatives ss00588 74 70 29 36 56 97 52 85 52 48 Amino Acids and Derivatives Aromatic amino acids and derivatives ss00690 32 25 0 3 1 3 2 2 2 2 Amino Acids and Derivatives Aromatic amino acids and derivatives ss00728 356 279 132 163 234 407 255 444 238 173 Amino Acids and Derivatives Aromatic amino acids and derivatives ss00744 12 11 12 14 8 17 4 8 13 14 Amino Acids and Derivatives Aromatic amino acids and derivatives ss00875 303 254 140 155 199 388 239 418 239 195 Amino Acids and Derivatives Aromatic amino acids and derivatives ss00886 173 148 99 106 105 227 111 224 137 122 Amino Acids and Derivatives Branched-chain amino acids ss00048 359 320 276 320 388 694 423 729 416 368 Amino Acids and Derivatives Branched-chain amino acids ss00139 42 38 23 36 36 53 32 57 38 26 Amino Acids and Derivatives Branched-chain amino acids ss00368 128 118 63 78 89 162 79 144 95 88 Amino Acids and Derivatives Branched-chain amino acids ss00415 147 127 104 111 126 214 124 227 146 120 Amino Acids and Derivatives Branched-chain amino acids ss00440 174 180 89 99 140 258 138 240 137 117 Amino Acids and Derivatives Branched-chain amino acids ss00601 676 618 325 414 529 1016 605 1086 525 461 Amino Acids and Derivatives Branched-chain amino acids ss00613 294 270 219 256 279 469 266 451 315 263 Amino Acids and Derivatives Branched-chain amino acids ss00654 134 122 84 101 95 140 90 148 101 82 Amino Acids and Derivatives Glutamine, glutamate, aspartate, asparagine; ammonia assimilation ss00700 721 643 370 450 525 1012 576 1059 603 491 Amino Acids and Derivatives Glutamine, glutamate, aspartate, asparagine; ammonia assimilation ss00976 69 64 32 37 58 92 44 97 52 37 Amino Acids and Derivatives Histidine Metabolism ss00293 101 87 61 77 88 168 103 166 128 105 Amino Acids and Derivatives Histidine Metabolism ss01022 588 523 325 380 528 934 557 913 510 412 Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine ss00075 220 175 152 188 299 586 344 717 231 198 Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine ss00172 330 315 165 186 269 466 320 550 279 234 Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine ss00206 165 152 91 113 115 194 111 200 140 120 Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine ss00224 109 106 51 63 60 122 64 125 62 60 Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine ss00478 625 601 349 414 567 937 549 1049 560 402 Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine ss00656 407 373 135 163 231 421 252 464 275 208 Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine ss00779 179 168 50 59 35 67 38 73 87 79 Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine ss00786 698 642 371 420 566 932 581 1074 595 494 Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine ss00991 8 8 1 2 4 8 3 11 3 2 Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine ss01009 359 377 199 227 343 606 320 613 305 258 Amino Acids and Derivatives Proline and 4-hydroxyproline ss00125 645 591 326 438 516 867 464 854 502 423 Amino Acids and Derivatives Proline and 4-hydroxyproline ss00163 35 27 14 14 26 42 27 39 17 18 Amino Acids and Derivatives Proline and 4-hydroxyproline ss00594 72 66 29 39 54 92 52 96 52 44 Amino Acids and Derivatives Unclassified Subsystem ss00418 5 5 6 8 4 8 5 5 6 7 Carbohydrates Aminosugars ss00475 1 1 0 0 3 8 6 10 0 1 Carbohydrates Aminosugars ss00497 207 153 138 116 208 336 187 405 158 101 Carbohydrates Aminosugars ss00963 71 68 27 38 46 70 43 75 51 41 Carbohydrates Aminosugars ss01090 166 135 118 134 105 192 148 232 160 147 Carbohydrates CO2 fixation ss00112 8 8 5 9 5 8 9 22 8 5 Carbohydrates CO2 fixation ss00423 346 300 186 210 203 340 197 364 220 171 Carbohydrates CO2 fixation ss00504 354 298 159 181 192 365 252 477 234 195 Carbohydrates CO2 fixation ss00812 271 213 115 119 80 128 200 533 181 132 Carbohydrates Central carbohydrate metabolism ss00105 441 341 220 288 283 461 307 554 355 291 Carbohydrates Central carbohydrate metabolism ss00135 748 639 423 537 549 960 544 1075 614 530 Carbohydrates Central carbohydrate metabolism ss00240 154 139 103 132 138 291 156 292 169 134 Carbohydrates Central carbohydrate metabolism ss00409 607 577 360 411 479 989 517 1098 517 464 Carbohydrates Central carbohydrate metabolism ss00457 548 469 324 383 408 717 420 824 459 391 Carbohydrates Central carbohydrate metabolism ss00460 167 152 109 117 150 267 169 323 147 129 Carbohydrates Central carbohydrate metabolism ss00642 230 160 22 43 4 7 5 13 107 93 Carbohydrates Central carbohydrate metabolism ss00685 349 296 125 149 183 318 189 355 185 147 Carbohydrates Central carbohydrate metabolism ss00842 240 181 144 159 174 306 179 333 234 192 Carbohydrates Central carbohydrate metabolism ss00863 584 513 238 294 384 640 384 729 362 273 Carbohydrates Central carbohydrate metabolism ss00932 185 216 79 110 174 332 183 347 142 129 Carbohydrates Central carbohydrate metabolism ss00954 134 144 72 84 76 138 82 147 115 97 Carbohydrates Central carbohydrate metabolism ss00998 1034 997 583 695 773 1391 860 1577 841 689 Carbohydrates Central carbohydrate metabolism ss01031 475 400 284 314 277 510 305 522 349 318 Carbohydrates Di- and oligosaccharides ss00113 109 101 32 52 111 202 115 231 65 43 Carbohydrates Di- and oligosaccharides ss00218 144 107 51 71 98 196 90 183 95 68 Carbohydrates Di- and oligosaccharides ss00386 659 525 388 483 703 1353 622 1264 612 480 Carbohydrates Di- and oligosaccharides ss00470 54 48 43 49 80 134 79 154 67 53 Carbohydrates Di- and oligosaccharides ss00641 1357 903 853 1022 644 1374 1198 2296 926 800 Carbohydrates Di- and oligosaccharides ss00725 139 141 82 88 109 176 89 173 120 100 Carbohydrates Di- and oligosaccharides ss00826 9 9 4 5 8 14 11 23 6 6 Carbohydrates Di- and oligosaccharides ss00885 705 628 406 496 707 1282 735 1511 555 497 Carbohydrates Di- and oligosaccharides ss00904 2 2 1 0 0 0 1 2 1 0 Carbohydrates Di- and oligosaccharides ss00915 216 201 111 134 201 322 178 370 135 122 Carbohydrates Di- and oligosaccharides ss00969 205 175 94 115 168 324 189 342 143 125 Carbohydrates Fermentation ss00003 364 325 232 285 305 564 322 570 389 343 Carbohydrates Fermentation ss00060 305 292 198 239 237 379 221 457 302 229 Carbohydrates Fermentation ss00087 216 162 115 150 130 221 138 289 176 155 Carbohydrates Fermentation ss00153 131 110 87 93 77 132 62 111 107 90 Carbohydrates Fermentation ss00216 14 17 5 5 3 13 6 11 8 7 Carbohydrates Fermentation ss00802 219 187 111 133 134 226 141 271 161 144 Carbohydrates Glycoside hydrolases ss00508 83 78 40 42 35 52 39 100 64 45 Carbohydrates Monosaccharides ss00001 2 6 8 7 5 8 5 10 7 4 Carbohydrates Monosaccharides ss00043 172 143 70 93 150 215 152 281 116 86 Carbohydrates Monosaccharides ss00084 10 8 10 7 8 19 15 34 7 4 Carbohydrates Monosaccharides ss00151 23 36 16 15 18 49 36 57 26 23 Carbohydrates Monosaccharides ss00189 30 23 29 28 52 65 39 53 32 30 Carbohydrates Monosaccharides ss00190 31 29 7 11 26 50 25 43 16 9 Carbohydrates Monosaccharides ss00201 189 161 91 131 215 390 206 410 167 131 Carbohydrates Monosaccharides ss00220 108 105 41 62 150 276 141 304 72 54 Carbohydrates Monosaccharides ss00227 204 208 179 207 194 378 196 383 218 198 Carbohydrates Monosaccharides ss00349 348 265 128 179 261 463 284 459 195 172 Carbohydrates Monosaccharides ss00359 143 129 114 140 178 324 186 344 143 125 Carbohydrates Monosaccharides ss00468 41 42 17 20 29 47 33 56 25 25 Carbohydrates Monosaccharides ss00537 71 72 40 49 103 184 90 174 46 56 Carbohydrates Monosaccharides ss00644 70 60 42 49 38 56 34 66 47 45 Carbohydrates Monosaccharides ss00746 66 53 56 48 78 141 71 142 76 53 Carbohydrates Monosaccharides ss00758 326 286 181 225 337 626 404 763 267 224 Carbohydrates Monosaccharides ss00833 68 51 54 58 45 67 38 76 60 51 Carbohydrates Monosaccharides ss00836 143 151 86 90 155 256 154 305 131 91 Carbohydrates Monosaccharides ss00939 50 49 29 37 69 126 80 117 57 50 Carbohydrates One-carbon Metabolism ss00181 101 58 23 32 31 49 23 38 31 19 Carbohydrates One-carbon Metabolism ss00311 26 25 9 8 6 17 6 22 4 5 Carbohydrates One-carbon Metabolism ss00466 78 81 28 37 58 117 60 125 65 57 Carbohydrates One-carbon Metabolism ss00487 251 223 148 192 186 317 176 337 205 164 Carbohydrates One-carbon Metabolism ss00689 992 863 539 634 861 1542 876 1623 824 666 Carbohydrates Organic acids ss00069 6 7 13 23 9 17 6 8 14 12 Carbohydrates Organic acids ss00086 158 141 128 145 178 304 174 370 188 147 Carbohydrates Organic acids ss00121 31 31 89 128 44 98 48 91 124 128 Carbohydrates Organic acids ss00194 94 81 52 55 38 77 37 64 54 49 Carbohydrates Organic acids ss00273 188 172 101 119 198 347 208 371 170 144 Carbohydrates Organic acids ss00326 296 277 145 196 270 439 251 469 247 210 Carbohydrates Organic acids ss00862 4 2 2 5 3 2 1 3 2 2 Carbohydrates Organic acids ss00891 68 70 45 54 64 124 62 118 73 59 Carbohydrates Organic acids ss00911 3 5 1 1 4 8 3 11 3 3 Carbohydrates Organic acids ss00989 59 50 32 36 31 60 35 70 39 39 Carbohydrates Polysaccharides ss00114 38 27 9 13 19 38 26 58 11 8 Carbohydrates Polysaccharides ss00449 641 548 315 367 326 515 303 635 373 311 Carbohydrates Polysaccharides ss00500 0 3 1 0 2 1 0 0 0 0 Carbohydrates Sugar alcohols ss00055 68 70 53 59 58 132 74 133 65 68 Carbohydrates Sugar alcohols ss00250 180 167 112 137 235 458 230 472 197 143 Carbohydrates Sugar alcohols ss00462 25 33 16 26 38 72 42 68 28 25 Carbohydrates Sugar alcohols ss00490 40 41 22 32 37 68 42 81 31 25 Carbohydrates Sugar alcohols ss00724 10 16 13 7 4 5 8 10 5 2 Carbohydrates Sugar alcohols ss00970 112 95 47 46 98 174 106 186 91 70 Carbohydrates Sugar alcohols ss00988 315 272 174 203 266 522 296 511 238 194 Carbohydrates Unclassified Subsystem ss00496 77 60 14 15 19 32 12 29 20 10 Carbohydrates Unclassified Subsystem ss01087 71 55 37 40 41 78 43 84 52 44 Cell Division and Cell Cycle Cell cycle in Prokaryota ss00421 1097 888 573 664 743 1233 806 1421 728 597 Cell Division and Cell Cycle Cell cycle in Prokaryota ss00435 153 150 114 130 118 182 255 550 144 113 Cell Division and Cell Cycle Cell cycle in Prokaryota ss00494 428 386 217 239 337 619 412 762 344 281 Cell Division and Cell Cycle Cell cycle in Prokaryota ss00569 285 280 135 178 291 541 293 536 251 199 Cell Division and Cell Cycle Cell cycle in Prokaryota ss00929 1 1 0 0 4 8 9 25 1 0 Cell Division and Cell Cycle Cell cycle in Prokaryota ss01044 1 6 4 4 5 7 2 5 1 4 Cell Division and Cell Cycle Control of Macromolecuar Synthesis ss00196 261 211 116 132 107 193 118 209 127 110 Cell Division and Cell Cycle Unclassified Subsystem ss00902 37 33 16 12 26 38 26 47 28 25 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00016 2 3 3 2 2 2 2 3 2 1 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00067 3 5 1 2 2 3 1 2 1 5 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00199 296 280 155 171 246 445 276 502 201 200 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00204 40 38 18 32 30 48 24 61 36 31 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00244 232 202 110 116 205 330 181 328 139 119 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00281 3 0 3 5 3 3 1 3 3 1 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00330 109 90 75 71 63 133 54 126 66 63 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00351 59 56 24 27 24 46 25 69 30 23 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00427 52 43 14 21 18 34 23 46 32 32 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00456 3 4 1 1 1 4 2 3 2 2 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00638 2 2 1 0 0 1 0 2 1 1 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00715 107 92 62 78 82 141 104 193 71 69 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00774 135 129 75 89 100 200 134 238 99 83 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00827 2 0 1 1 1 3 1 1 0 0 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00840 159 158 92 130 109 183 113 204 164 112 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00853 210 187 115 147 151 282 150 295 164 138 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00868 2 2 2 2 1 1 1 2 2 2 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00959 5 2 3 4 3 6 4 5 3 2 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00972 301 254 162 194 227 451 323 565 232 234 Cell Wall and Capsule Capsular and extracellular polysacchrides ss00986 0 0 0 0 0 0 0 1 0 0 Cell Wall and Capsule Cell wall of Mycobacteria ss00525 15 12 19 17 20 35 17 30 11 15 Cell Wall and Capsule Gram-Negative cell wall components ss00259 216 204 95 114 86 143 82 139 135 122 Cell Wall and Capsule Gram-Negative cell wall components ss00279 33 25 13 21 15 27 14 30 27 31 Cell Wall and Capsule Gram-Negative cell wall components ss00346 62 54 27 31 42 51 29 83 43 32 Cell Wall and Capsule Gram-Negative cell wall components ss00362 255 230 128 151 104 186 105 199 210 163 Cell Wall and Capsule Gram-Negative cell wall components ss00553 18 16 18 14 10 18 12 12 15 13 Cell Wall and Capsule Gram-Negative cell wall components ss00719 409 403 199 246 125 269 140 294 289 259 Cell Wall and Capsule Gram-Negative cell wall components ss00906 33 26 24 31 16 38 17 30 27 20 Cell Wall and Capsule Gram-Negative cell wall components ss01048 224 165 121 147 188 346 201 370 180 146 Cell Wall and Capsule Gram-Positive cell wall components ss00177 1 2 2 1 1 2 2 3 2 0 Cell Wall and Capsule Gram-Positive cell wall components ss00828 194 173 97 123 136 260 163 271 135 110 Cell Wall and Capsule Gram-Positive cell wall components ss01025 92 102 59 72 111 187 122 241 87 78 Cell Wall and Capsule Unclassified Subsystem ss00146 0 0 0 0 2 2 2 5 1 1 Cell Wall and Capsule Unclassified Subsystem ss00156 704 600 339 416 499 829 485 908 531 460 Cell Wall and Capsule Unclassified Subsystem ss00830 187 192 112 133 223 365 203 408 190 149 Cell Wall and Capsule Unclassified Subsystem ss01076 168 128 67 88 110 143 89 162 114 93 Clustering-based subsystems An uncharacterized, possibly regulatory, protein relating to translation ss00459 50 48 23 31 51 74 64 116 33 27 Clustering-based subsystems Biosynthesis of galactoglycans and related lipopolysacharides ss00175 2 1 0 1 1 0 0 1 0 0 Clustering-based subsystems Biosynthesis of galactoglycans and related lipopolysacharides ss00660 254 224 185 234 207 394 225 435 236 208 Clustering-based subsystems CRISPRs and associated hypotheticals ss00768 27 20 7 12 7 19 15 18 11 5 Clustering-based subsystems Carbohydrates ss00634 73 65 34 50 40 70 37 69 42 42 Clustering-based subsystems Carbohydrates ss00838 4 4 2 2 3 3 4 6 2 2 Clustering-based subsystems Carbohydrates ss00945 5 5 4 8 8 10 12 14 5 4 Clustering-based subsystems Carotenoid biosynthesis ss00631 74 56 53 57 43 81 49 96 66 52 Clustering-based subsystems Catabolism of an unknown compound ss00618 22 28 21 24 54 107 55 92 33 25 Clustering-based subsystems Cell Division ss00037 272 210 115 152 119 180 126 208 128 113 Clustering-based subsystems Cell Division ss00143 12 13 5 3 5 8 4 7 6 4 Clustering-based subsystems Cell Division ss00276 62 73 34 48 71 99 75 134 51 49 Clustering-based subsystems Chemotaxis, response regulators ss00392 18 22 11 10 10 26 16 25 9 9 Clustering-based subsystems Choline bitartrate degradation, putative ss00580 16 10 15 15 28 36 27 33 18 15 Clustering-based subsystems Clustering-based subsystems ss00053 25 17 12 18 16 39 19 34 29 18 Clustering-based subsystems Clustering-based subsystems ss00599 62 64 33 33 42 80 41 90 43 33 Clustering-based subsystems Clustering-based subsystems ss00933 10 7 7 5 18 21 13 18 5 3 Clustering-based subsystems Clustering-based subsystems ss00949 4 5 3 2 1 4 3 5 3 4 Clustering-based subsystems Cytochrome biogenesis ss00374 347 305 163 242 376 726 397 761 346 269 Clustering-based subsystems Cytochrome biogenesis ss01050 66 57 38 36 79 135 77 131 66 48 Clustering-based subsystems D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-) cluster ss00070 125 120 84 87 141 255 136 236 133 89 Clustering-based subsystems DNA metabolism ss00329 43 29 13 20 33 46 21 52 15 15 Clustering-based subsystems DNA polymerase III epsilon cluster ss00717 77 92 38 49 63 101 85 159 61 50 Clustering-based subsystems Fatty acid metabolic cluster ss00319 275 258 281 322 324 597 305 563 367 321 Clustering-based subsystems Fatty acid metabolic cluster ss00412 326 275 210 262 152 272 146 308 354 281 Clustering-based subsystems Flagella protein? ss00864 41 38 18 30 19 31 17 27 20 20 Clustering-based subsystems Hypothetical Related to Dihydroorate Dehydrogenase ss01059 8 7 6 8 5 4 2 6 3 2 Clustering-based subsystems Hypothetical associated with RecF ss00621 184 188 92 99 154 241 176 302 145 112 Clustering-based subsystems Hypothetical in Lysine biosynthetic cluster ss00766 104 83 54 60 81 121 64 91 70 56 Clustering-based subsystems Hypothetical lipase related to Phosphatidate metabolism ss01035 21 19 18 20 12 24 14 22 23 13 Clustering-based subsystems Hypothetical protein possible functionally linked with Alanyl-tRNA synthetase ss00263 81 80 43 47 66 106 57 118 49 40 Clustering-based subsystems Isoprenoid/cell wall biosynthesis: PREDICTED UNDECAPRENYL DIPHOSPHATE PHOSPHATASE ss00994 166 125 72 84 123 190 116 223 110 89 Clustering-based subsystems Lipoprotein B cluster ss00878 43 35 21 32 18 28 16 37 24 26 Clustering-based subsystems Lysine Biosynthesis ss00191 12 21 11 9 27 32 14 28 12 13 Clustering-based subsystems Lysine, threonine, methionine, and cysteine ss00050 18 14 14 23 7 16 16 25 14 13 Clustering-based subsystems Lysine, threonine, methionine, and cysteine ss00052 86 80 37 52 81 124 81 148 68 62 Clustering-based subsystems Membrane-bound hydrogenase ss01026 1 0 0 0 0 0 0 0 0 0 Clustering-based subsystems Methylamine utilization ss00019 31 24 40 43 43 100 43 78 56 44 Clustering-based subsystems Molybdopterin oxidoreductase ss00763 79 77 61 63 19 46 21 50 66 67 Clustering-based subsystems Monosaccharides ss00107 63 50 28 27 50 81 39 83 41 36 Clustering-based subsystems Nucleotidyl-phosphate metabolic cluster ss00651 1 2 0 1 1 0 0 1 0 0 Clustering-based subsystems Pigment biosynthesis ss01065 11 11 4 4 21 38 17 37 11 12 Clustering-based subsystems Probably GTP or GMP signaling related ss00604 407 374 220 267 338 598 346 640 338 265 Clustering-based subsystems Probably Pyrimidine biosynthesis-related ss00847 18 19 6 8 8 10 6 15 8 9 Clustering-based subsystems Probably Ybbk-related hypothetical membrane proteins ss00858 29 19 20 13 15 20 18 43 22 18 Clustering-based subsystems Probably organic hydroperoxide resistance related hypothetical protein ss00106 26 23 28 27 45 63 50 80 37 27 Clustering-based subsystems Proteasome related clusters ss00179 0 0 0 0 0 0 0 0 0 0 Clustering-based subsystems Protein export? ss00315 447 408 216 240 254 419 292 515 289 233 Clustering-based subsystems Putative GGDEF domain protein related to agglutinin secretion ss00592 24 21 11 12 21 46 51 68 15 16 Clustering-based subsystems Putative Isoquinoline 1-oxidoreductase subunit ss00477 108 110 146 170 105 188 107 174 186 152 Clustering-based subsystems Putative asociate of RNA polymerase sigma-54 factor rpoN ss00726 279 232 255 280 342 601 336 586 402 386 Clustering-based subsystems Putrescine/GABA utilization cluster-temporal,to add to SSs ss00170 24 29 17 24 25 37 10 25 21 17 Clustering-based subsystems Pyruvate kinase associated cluster ss00927 14 23 24 22 5 12 5 14 22 12 Clustering-based subsystems Recombination related cluster ss00894 28 22 16 18 12 18 16 34 22 14 Clustering-based subsystems Related to Menaquinone-cytochrome C reductase ss00731 2 1 4 3 1 2 1 6 3 3 Clustering-based subsystems Related to N-acetylglucosamine utilization subsystem? ss01029 24 20 12 14 41 68 31 61 15 16 Clustering-based subsystems Ribosomal Protein L28P relates to a set of uncharacterized proteins ss01032 48 24 26 25 27 40 29 42 29 24 Clustering-based subsystems Ribosome-related cluster ss00542 4 4 1 3 2 3 2 4 2 1 Clustering-based subsystems Ribosome-related cluster ss00764 85 77 37 46 66 124 75 113 55 43 Clustering-based subsystems Sarcosine oxidase ss00785 36 31 18 21 27 56 28 66 22 20 Clustering-based subsystems Shiga toxin cluster ss01085 0 1 0 0 1 0 0 0 1 0 Clustering-based subsystems Sulfatases and sulfatase modifying factor 1 (and a hypothetical) ss00772 217 179 139 159 158 298 153 344 195 164 Clustering-based subsystems Three hypotheticals linked to lipoprotein biosynthesis ss00849 52 36 26 33 33 50 36 55 29 25 Clustering-based subsystems TldD cluster ss00255 111 81 50 50 53 83 55 86 39 44 Clustering-based subsystems Translation ss00178 16 13 7 9 8 10 8 11 7 9 Clustering-based subsystems Translation ss00546 135 130 52 68 69 131 60 160 87 73 Clustering-based subsystems Tricarboxylate transporter ss01038 254 250 147 166 187 394 168 330 208 225 Clustering-based subsystems Two related proteases ss00680 44 42 15 34 23 34 15 34 33 26 Clustering-based subsystems Type III secretion system, extended ss00822 9 11 6 8 14 31 16 25 11 10 Clustering-based subsystems Unclassified Subsystem ss00011 124 117 60 73 101 163 93 177 81 69 Clustering-based subsystems Unclassified Subsystem ss00015 55 51 24 29 46 82 52 101 56 47 Clustering-based subsystems Unclassified Subsystem ss00027 98 86 76 87 75 141 75 143 82 66 Clustering-based subsystems Unclassified Subsystem ss00054 2 1 1 0 1 1 1 0 1 2 Clustering-based subsystems Unclassified Subsystem ss00061 44 39 14 23 26 46 42 60 27 20 Clustering-based subsystems Unclassified Subsystem ss00065 145 112 55 64 221 363 199 358 107 78 Clustering-based subsystems Unclassified Subsystem ss00104 91 96 45 56 57 84 52 88 65 57 Clustering-based subsystems Unclassified Subsystem ss00120 181 167 84 89 143 271 164 301 135 120 Clustering-based subsystems Unclassified Subsystem ss00132 16 13 8 11 41 75 37 64 17 16 Clustering-based subsystems Unclassified Subsystem ss00171 119 120 62 67 40 63 37 79 74 69 Clustering-based subsystems Unclassified Subsystem ss00176 37 25 10 17 14 35 14 30 17 20 Clustering-based subsystems Unclassified Subsystem ss00193 1 0 1 1 1 1 1 1 0 0 Clustering-based subsystems Unclassified Subsystem ss00232 73 63 36 44 34 60 34 71 50 25 Clustering-based subsystems Unclassified Subsystem ss00243 32 30 31 39 24 59 59 134 33 29 Clustering-based subsystems Unclassified Subsystem ss00248 366 358 194 239 314 608 382 745 326 255 Clustering-based subsystems Unclassified Subsystem ss00265 10 14 5 1 6 7 3 5 0 1 Clustering-based subsystems Unclassified Subsystem ss00266 132 115 51 49 38 104 55 99 76 46 Clustering-based subsystems Unclassified Subsystem ss00270 73 65 43 57 90 164 93 144 55 48 Clustering-based subsystems Unclassified Subsystem ss00296 50 46 52 56 47 89 48 76 65 47 Clustering-based subsystems Unclassified Subsystem ss00302 277 237 173 186 258 459 252 531 229 175 Clustering-based subsystems Unclassified Subsystem ss00309 48 33 34 25 45 90 39 71 47 35 Clustering-based subsystems Unclassified Subsystem ss00320 6 4 0 0 1 2 0 0 3 3 Clustering-based subsystems Unclassified Subsystem ss00323 6 12 2 4 9 9 3 12 8 5 Clustering-based subsystems Unclassified Subsystem ss00338 22 24 13 15 12 25 10 21 18 11 Clustering-based subsystems Unclassified Subsystem ss00350 21 16 17 9 15 23 17 55 8 2 Clustering-based subsystems Unclassified Subsystem ss00352 47 35 32 37 10 24 4 15 35 30 Clustering-based subsystems Unclassified Subsystem ss00379 77 66 31 47 62 112 58 123 57 39 Clustering-based subsystems Unclassified Subsystem ss00382 314 276 163 203 293 547 332 545 251 215 Clustering-based subsystems Unclassified Subsystem ss00399 22 23 13 18 17 30 21 35 18 18 Clustering-based subsystems Unclassified Subsystem ss00437 205 194 113 111 160 251 141 277 134 107 Clustering-based subsystems Unclassified Subsystem ss00479 87 68 49 60 67 127 82 154 64 46 Clustering-based subsystems Unclassified Subsystem ss00498 5 2 2 1 38 52 21 26 6 3 Clustering-based subsystems Unclassified Subsystem ss00517 3 1 0 0 1 0 1 2 1 1 Clustering-based subsystems Unclassified Subsystem ss00550 7 7 12 6 5 4 4 5 10 7 Clustering-based subsystems Unclassified Subsystem ss00609 11 4 6 3 2 3 1 4 2 3 Clustering-based subsystems Unclassified Subsystem ss00619 40 35 20 25 22 39 14 42 29 22 Clustering-based subsystems Unclassified Subsystem ss00630 316 248 118 170 130 203 94 179 191 170 Clustering-based subsystems Unclassified Subsystem ss00632 104 93 61 68 57 93 54 101 73 56 Clustering-based subsystems Unclassified Subsystem ss00645 48 35 38 41 115 160 82 142 58 45 Clustering-based subsystems Unclassified Subsystem ss00649 111 113 67 64 86 141 86 171 78 70 Clustering-based subsystems Unclassified Subsystem ss00665 34 21 13 24 12 20 14 23 17 23 Clustering-based subsystems Unclassified Subsystem ss00694 253 202 126 152 200 358 219 440 192 158 Clustering-based subsystems Unclassified Subsystem ss00708 185 149 86 95 140 251 134 254 138 115 Clustering-based subsystems Unclassified Subsystem ss00727 684 579 329 378 539 882 560 995 556 459 Clustering-based subsystems Unclassified Subsystem ss00738 255 225 155 166 206 349 210 390 195 164 Clustering-based subsystems Unclassified Subsystem ss00747 4 4 0 0 1 2 1 0 0 0 Clustering-based subsystems Unclassified Subsystem ss00820 178 172 82 108 146 254 164 274 147 130 Clustering-based subsystems Unclassified Subsystem ss00843 62 75 36 40 29 58 34 51 46 46 Clustering-based subsystems Unclassified Subsystem ss00908 434 378 179 204 302 562 337 612 305 247 Clustering-based subsystems Unclassified Subsystem ss00910 130 113 56 46 50 97 60 111 72 60 Clustering-based subsystems Unclassified Subsystem ss00917 69 58 35 39 38 64 42 86 37 34 Clustering-based subsystems Unclassified Subsystem ss00919 12 6 2 2 3 5 2 9 2 3 Clustering-based subsystems Unclassified Subsystem ss00920 75 61 33 39 51 85 47 92 53 46 Clustering-based subsystems Unclassified Subsystem ss00930 0 1 0 0 0 1 0 1 0 0 Clustering-based subsystems Unclassified Subsystem ss00942 184 162 84 97 145 267 150 262 134 123 Clustering-based subsystems Unclassified Subsystem ss00987 45 49 23 25 27 42 24 42 29 22 Clustering-based subsystems Unclassified Subsystem ss00993 90 62 74 80 85 119 60 102 77 57 Clustering-based subsystems Unclassified Subsystem ss01002 175 128 184 220 160 280 181 295 274 228 Clustering-based subsystems Unclassified Subsystem ss01014 109 84 72 77 109 178 113 199 93 69 Clustering-based subsystems Unclassified Subsystem ss01030 173 137 67 71 152 213 135 271 113 108 Clustering-based subsystems Unclassified Subsystem ss01069 4 3 4 5 4 10 5 1 2 2 Clustering-based subsystems Unclassified Subsystem ss01093 180 157 106 135 159 257 163 303 159 132 Clustering-based subsystems Urate degradation ss00451 24 26 16 32 25 57 23 52 29 23 Clustering-based subsystems alpha-proteobacterial cluster of hypotheticals ss00901 70 54 36 46 30 38 29 40 46 45 Clustering-based subsystems proteosome related ss00913 61 56 50 62 212 328 181 362 74 50 Clustering-based subsystems recX and regulatory cluster ss00633 10 9 6 9 6 11 6 11 10 7 Clustering-based subsystems tRNA sulfuration ss00238 48 41 28 34 63 111 65 105 39 32 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin ss01013 614 525 413 495 502 889 470 880 615 471 Cofactors, Vitamins, Prosthetic Groups, Pigments Coenzyme A ss00581 450 384 238 231 359 594 378 636 357 311 Cofactors, Vitamins, Prosthetic Groups, Pigments Coenzyme B ss00383 0 0 0 0 0 0 0 0 0 0 Cofactors, Vitamins, Prosthetic Groups, Pigments Coenzyme F420 ss00956 44 30 40 41 112 160 98 193 72 54 Cofactors, Vitamins, Prosthetic Groups, Pigments Coenzyme M ss00229 75 60 29 38 25 52 31 66 51 43 Cofactors, Vitamins, Prosthetic Groups, Pigments Fe-S clusters ss00673 42 36 18 21 21 33 21 42 27 24 Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines ss00088 352 286 158 191 292 483 303 468 292 240 Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines ss00295 29 23 22 34 27 42 18 41 32 23 Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines ss00341 569 475 295 363 532 900 501 942 472 386 Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines ss00348 0 0 0 0 0 0 0 0 0 0 Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines ss00380 293 249 122 149 57 124 51 90 178 177 Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines ss00512 4 2 1 2 1 2 7 16 3 2 Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines ss00674 349 319 160 187 233 405 219 456 224 202 Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines ss00835 119 84 77 82 109 191 128 205 94 73 Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines ss00918 7 8 5 5 2 4 2 2 7 6 Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines ss01062 3 1 4 1 2 4 0 2 2 4 Cofactors, Vitamins, Prosthetic Groups, Pigments Lipoic acid ss00144 284 254 164 175 369 589 377 658 251 253 Cofactors, Vitamins, Prosthetic Groups, Pigments NAD and NADP ss00345 78 78 49 56 60 93 55 91 56 48 Cofactors, Vitamins, Prosthetic Groups, Pigments NAD and NADP ss00925 479 442 267 337 479 774 506 908 433 373 Cofactors, Vitamins, Prosthetic Groups, Pigments Pyridoxine ss00313 0 2 0 1 3 1 1 2 0 1 Cofactors, Vitamins, Prosthetic Groups, Pigments Pyridoxine ss00850 248 218 121 166 212 382 237 409 198 172 Cofactors, Vitamins, Prosthetic Groups, Pigments Quinone cofactors ss00004 120 97 59 62 185 304 158 353 98 92 Cofactors, Vitamins, Prosthetic Groups, Pigments Quinone cofactors ss00526 23 21 26 26 29 44 27 73 39 28 Cofactors, Vitamins, Prosthetic Groups, Pigments Quinone cofactors ss00574 138 125 205 217 118 218 124 230 278 216 Cofactors, Vitamins, Prosthetic Groups, Pigments Quinone cofactors ss00703 10 5 10 10 13 20 18 38 9 11 Cofactors, Vitamins, Prosthetic Groups, Pigments Quinone cofactors ss00771 11 6 9 9 14 23 18 51 11 11 Cofactors, Vitamins, Prosthetic Groups, Pigments Quinone cofactors ss00795 165 148 87 112 110 193 122 233 134 127 Cofactors, Vitamins, Prosthetic Groups, Pigments Riboflavin, FMN, FAD ss00034 181 180 101 138 173 279 203 347 168 143 Cofactors, Vitamins, Prosthetic Groups, Pigments Riboflavin, FMN, FAD ss00136 9 11 6 6 3 10 5 14 2 4 Cofactors, Vitamins, Prosthetic Groups, Pigments Riboflavin, FMN, FAD ss01073 27 29 13 20 13 26 20 26 18 16 Cofactors, Vitamins, Prosthetic Groups, Pigments Tetrapyrroles ss00235 261 233 127 161 161 236 232 450 183 135 Cofactors, Vitamins, Prosthetic Groups, Pigments Tetrapyrroles ss00252 343 300 160 202 293 477 274 481 259 189 Cofactors, Vitamins, Prosthetic Groups, Pigments Tetrapyrroles ss00544 442 369 225 280 461 704 493 858 310 264 Cofactors, Vitamins, Prosthetic Groups, Pigments Tetrapyrroles ss00783 42 46 6 2 16 28 22 32 15 10 Cofactors, Vitamins, Prosthetic Groups, Pigments Tetrapyrroles ss00895 189 140 89 109 271 401 264 484 135 111 Cofactors, Vitamins, Prosthetic Groups, Pigments Tetrapyrroles ss00977 1 0 0 0 4 3 8 25 0 2 Cofactors, Vitamins, Prosthetic Groups, Pigments Tetrapyrroles ss01084 0 4 4 6 3 6 7 27 4 6 Cofactors, Vitamins, Prosthetic Groups, Pigments Unclassified Subsystem ss00540 251 252 181 243 190 377 212 385 254 195 DNA Metabolism DNA recombination ss01056 184 176 91 105 158 248 163 307 141 142 DNA Metabolism DNA repair ss00090 0 0 0 0 0 0 0 0 0 1 DNA Metabolism DNA repair ss00092 788 669 433 568 749 1227 734 1299 600 533 DNA Metabolism DNA repair ss00335 18 9 5 11 8 19 11 14 12 13 DNA Metabolism DNA repair ss00337 94 64 54 49 49 86 56 91 73 55 DNA Metabolism DNA repair ss00433 100 89 58 79 92 159 123 193 87 78 DNA Metabolism DNA repair ss00531 831 742 349 407 521 1045 547 1150 564 485 DNA Metabolism DNA repair ss00623 205 203 97 117 83 146 71 152 145 118 DNA Metabolism DNA repair ss00635 509 491 315 387 625 1178 642 1159 560 471 DNA Metabolism DNA repair ss00679 365 310 124 184 114 227 152 270 216 175 DNA Metabolism DNA repair ss01081 252 230 134 166 297 529 317 552 197 159 DNA Metabolism DNA replication ss00310 117 107 77 96 114 226 119 223 92 109 DNA Metabolism DNA replication ss00381 286 276 119 145 185 345 202 404 199 181 DNA Metabolism DNA replication ss00442 13 12 0 5 24 41 22 48 3 5 DNA Metabolism DNA replication ss00600 1354 1175 654 704 903 1481 859 1662 900 727 DNA Metabolism DNA replication ss00668 4 3 1 1 1 3 4 1 2 1 DNA Metabolism DNA replication ss00760 44 37 16 17 22 44 25 50 23 17 DNA Metabolism DNA uptake, competence ss00818 3 2 1 1 1 1 0 2 1 1 DNA Metabolism Unclassified Subsystem ss00499 316 300 103 120 85 203 137 285 116 81 DNA Metabolism Unclassified Subsystem ss00757 138 115 111 110 107 177 102 206 130 123 DNA Metabolism Unclassified Subsystem ss00872 106 107 33 40 27 67 42 96 38 23 DNA Metabolism Unclassified Subsystem ss00952 44 42 20 29 33 53 22 64 35 27 DNA Metabolism Unclassified Subsystem ss01040 65 58 26 28 31 52 34 52 31 32 Dormancy and Sporulation Unclassified Subsystem ss00283 12 13 13 8 12 20 15 24 13 9 Dormancy and Sporulation Unclassified Subsystem ss00447 2 1 1 1 0 0 1 1 1 3 Dormancy and Sporulation Unclassified Subsystem ss00463 23 17 9 15 29 46 22 59 28 10 Dormancy and Sporulation Unclassified Subsystem ss00705 1 0 0 0 1 1 0 1 1 0 Dormancy and Sporulation Unclassified Subsystem ss00748 8 9 0 5 3 13 5 9 8 12 Fatty Acids, Lipids, and Isoprenoids Fatty acids ss00024 7 9 6 6 7 11 3 7 7 8 Fatty Acids, Lipids, and Isoprenoids Fatty acids ss00059 817 745 546 616 671 1101 626 1124 743 609 Fatty Acids, Lipids, and Isoprenoids Fatty acids ss00394 133 102 87 101 64 116 54 102 96 81 Fatty Acids, Lipids, and Isoprenoids Isoprenoids ss00294 349 313 172 182 327 581 347 637 313 250 Fatty Acids, Lipids, and Isoprenoids Isoprenoids ss00372 7 5 1 2 2 6 3 5 3 2 Fatty Acids, Lipids, and Isoprenoids Isoprenoids ss00515 169 154 74 96 117 250 113 257 113 107 Fatty Acids, Lipids, and Isoprenoids Isoprenoids ss00606 14 28 16 25 19 23 10 27 25 22 Fatty Acids, Lipids, and Isoprenoids Isoprenoids ss00861 0 0 0 0 0 0 1 2 0 0 Fatty Acids, Lipids, and Isoprenoids Isoprenoids ss01052 219 170 165 192 275 448 345 592 212 171 Fatty Acids, Lipids, and Isoprenoids Phospholipids ss00162 524 419 276 342 400 662 369 642 392 327 Fatty Acids, Lipids, and Isoprenoids Phospholipids ss00332 3 2 1 1 3 1 1 5 1 2 Fatty Acids, Lipids, and Isoprenoids Triacylglycerols ss00931 20 17 13 22 17 32 23 38 24 16 Fatty Acids, Lipids, and Isoprenoids Unclassified Subsystem ss00995 435 371 330 387 365 674 408 736 467 412 Membrane Transport ABC transporters ss00253 1 0 0 0 0 1 1 0 0 0 Membrane Transport ABC transporters ss00513 7 10 9 10 5 10 5 14 2 8 Membrane Transport ABC transporters ss00536 583 514 416 520 355 690 378 716 599 521 Membrane Transport ABC transporters ss00615 287 321 168 220 232 476 258 528 320 260 Membrane Transport ABC transporters ss00681 206 179 131 159 167 329 170 355 221 164 Membrane Transport ABC transporters ss00855 49 35 20 27 29 55 24 47 45 19 Membrane Transport ABC transporters ss01091 181 136 51 78 80 143 86 153 120 95 Membrane Transport SecY2-SecA2 specialized system ss01074 19 11 0 4 9 19 12 23 16 9 Membrane Transport Sugar Phosphotransferase Systems, PTS ss00300 1 2 3 3 7 2 3 7 2 2 Membrane Transport Unclassified Subsystem ss00111 68 53 37 31 45 78 53 94 45 28 Membrane Transport Unclassified Subsystem ss00262 52 37 31 37 36 49 37 58 48 36 Membrane Transport Unclassified Subsystem ss00307 583 476 386 467 272 456 342 620 490 369 Membrane Transport Unclassified Subsystem ss00659 138 120 91 116 102 202 107 221 136 104 Membrane Transport Unclassified Subsystem ss00753 4 3 1 0 0 2 2 2 1 1 Membrane Transport Unclassified Subsystem ss00848 21 21 11 9 10 28 11 26 18 12 Membrane Transport Unclassified Subsystem ss00940 46 43 15 23 88 128 95 175 30 36 Membrane Transport Unclassified Subsystem ss01049 48 48 36 39 48 78 64 103 42 30 Membrane Transport Uni- Sym- and Antiporters ss00231 16 20 1 4 32 56 38 65 3 5 Membrane Transport Uni- Sym- and Antiporters ss00290 88 89 20 22 93 156 116 180 32 36 Metabolism of Aromatic Compounds Anaerobic degradation of aromatic compounds ss00005 1 0 1 1 0 2 0 0 1 0 Metabolism of Aromatic Compounds Anaerobic degradation of aromatic compounds ss00155 100 79 34 36 24 47 20 51 69 43 Metabolism of Aromatic Compounds Metabolism of central aromatic intermediates ss00226 55 54 112 121 25 44 19 35 126 107 Metabolism of Aromatic Compounds Metabolism of central aromatic intermediates ss00246 109 90 95 108 136 212 156 288 119 98 Metabolism of Aromatic Compounds Metabolism of central aromatic intermediates ss00611 116 68 112 129 163 273 151 243 153 129 Metabolism of Aromatic Compounds Metabolism of central aromatic intermediates ss00730 104 105 95 108 85 173 81 139 127 106 Metabolism of Aromatic Compounds Metabolism of central aromatic intermediates ss00735 24 26 19 30 16 37 15 33 33 25 Metabolism of Aromatic Compounds Metabolism of central aromatic intermediates ss00996 105 91 82 96 148 236 140 299 120 93 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00089 17 14 21 17 3 12 8 16 11 21 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00103 7 6 3 6 9 14 5 15 7 6 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00133 15 9 20 19 14 26 9 23 16 14 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00149 24 21 24 28 29 44 18 33 21 28 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00161 9 6 11 14 18 28 18 34 15 6 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00167 449 368 315 392 426 720 390 712 503 383 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00222 89 68 96 87 78 144 65 146 101 95 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00316 21 10 10 7 13 25 15 20 10 5 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00524 9 7 17 21 7 13 5 10 18 10 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00658 52 40 75 87 84 145 79 154 87 55 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00675 22 20 16 14 20 38 21 37 33 22 Metabolism of Aromatic Compounds Peripheral pathways for catabolism of aromatic compounds ss00775 450 405 216 239 340 626 369 752 381 303 Metabolism of Aromatic Compounds Unclassified Subsystem ss00434 161 130 130 169 80 168 81 146 207 173 Metabolism of Aromatic Compounds Unclassified Subsystem ss00483 5 5 7 5 9 12 5 13 7 5 Metabolism of Aromatic Compounds Unclassified Subsystem ss00547 2 2 1 1 0 1 0 1 0 2 Metabolism of Aromatic Compounds Unclassified Subsystem ss00860 6 3 4 2 7 15 4 3 3 4 Metabolism of Aromatic Compounds Unclassified Subsystem ss00888 95 86 108 138 103 215 117 234 128 115 Metabolism of Aromatic Compounds Unclassified Subsystem ss00944 102 89 121 149 112 231 122 244 138 122 Metabolism of Aromatic Compounds Unclassified Subsystem ss01078 38 32 33 44 34 60 31 61 44 44 Miscellaneous Unclassified Subsystem ss00159 96 72 42 55 62 120 86 133 84 64 Miscellaneous Unclassified Subsystem ss00314 1 2 0 1 1 1 0 0 1 0 Miscellaneous Unclassified Subsystem ss00529 7 3 1 0 18 20 18 33 3 2 Miscellaneous Unclassified Subsystem ss00556 0 0 0 0 0 0 0 0 0 0 Miscellaneous Unclassified Subsystem ss00782 601 558 317 423 492 787 547 986 450 397 Miscellaneous Unclassified Subsystem ss00893 14 13 9 9 13 20 18 28 17 8 Miscellaneous Unclassified Subsystem ss00909 0 0 0 0 0 0 0 0 0 0 Miscellaneous Unclassified Subsystem ss00974 14 4 10 8 7 27 11 20 11 8 Motility and Chemotaxis Flagellar motility in Prokaryota ss00030 2 1 1 0 0 1 0 2 0 0 Motility and Chemotaxis Flagellar motility in Prokaryota ss00419 383 354 177 227 240 436 267 492 238 195 Motility and Chemotaxis Flagellar motility in Prokaryota ss00589 59 58 28 36 47 79 43 71 31 27 Motility and Chemotaxis Flagellar motility in Prokaryota ss00741 754 690 383 450 516 943 493 915 480 407 Motility and Chemotaxis Social motility and nonflagellar swimming in bacteria ss00082 1 1 1 0 1 1 1 0 0 1 Motility and Chemotaxis Unclassified Subsystem ss00076 802 726 496 530 636 1037 678 1207 622 556 Nitrogen Metabolism Unclassified Subsystem ss00049 110 86 112 115 143 299 155 248 128 127 Nitrogen Metabolism Unclassified Subsystem ss00142 775 697 354 473 424 861 446 831 570 474 Nitrogen Metabolism Unclassified Subsystem ss00152 30 26 5 1 3 6 5 8 7 6 Nitrogen Metabolism Unclassified Subsystem ss00174 78 61 18 13 12 22 16 34 39 34 Nitrogen Metabolism Unclassified Subsystem ss00793 201 211 28 44 52 79 62 121 55 38 Nitrogen Metabolism Unclassified Subsystem ss00935 118 119 94 127 100 165 91 182 101 93 Nitrogen Metabolism Unclassified Subsystem ss00946 63 41 8 17 29 45 29 47 22 16 Nitrogen Metabolism Unclassified Subsystem ss00968 32 32 34 43 17 42 20 46 47 47 Nitrogen Metabolism Unclassified Subsystem ss01045 307 276 168 229 386 680 303 556 277 271 Nitrogen Metabolism Unclassified Subsystem ss01094 32 35 31 42 84 107 63 113 49 48 Nucleosides and Nucleotides Detoxification ss00734 32 31 13 17 34 43 23 47 25 17 Nucleosides and Nucleotides Detoxification ss00958 83 78 48 66 85 135 79 168 62 51 Nucleosides and Nucleotides Purines ss00063 2 2 0 1 1 0 1 1 1 2 Nucleosides and Nucleotides Purines ss00134 1 0 5 2 0 1 1 3 2 1 Nucleosides and Nucleotides Purines ss00808 767 707 356 447 634 1073 664 1216 610 477 Nucleosides and Nucleotides Purines ss00821 865 789 392 423 619 1136 681 1176 621 508 Nucleosides and Nucleotides Pyrimidines ss00219 94 72 66 83 55 110 46 111 91 72 Nucleosides and Nucleotides Pyrimidines ss00896 502 449 243 292 445 814 508 939 449 339 Nucleosides and Nucleotides Unclassified Subsystem ss00099 189 160 94 106 104 179 99 183 144 127 Nucleosides and Nucleotides Unclassified Subsystem ss00471 2 1 0 0 0 0 0 0 0 0 Nucleosides and Nucleotides Unclassified Subsystem ss00664 495 452 221 301 409 750 415 814 387 328 Nucleosides and Nucleotides Unclassified Subsystem ss00713 240 225 207 261 248 500 289 553 344 308 Nucleosides and Nucleotides Unclassified Subsystem ss00714 421 347 179 216 194 388 245 422 283 224 Nucleosides and Nucleotides Unclassified Subsystem ss01005 196 169 154 199 276 444 221 411 227 187 Phages, Prophages, Transposable elements Bacteriophage integration/excision/lysogeny ss01075 17 18 14 11 8 18 8 28 8 5 Phages, Prophages, Transposable elements Bacteriophage structural proteins ss00221 6 3 1 2 2 4 1 3 2 1 Phages, Prophages, Transposable elements Lysogenic conversion ss00884 0 0 0 0 0 0 0 0 0 0 Phages, Prophages, Transposable elements Regulation of Expression ss00469 0 0 0 0 0 0 0 0 0 0 Phages, Prophages, Transposable elements Superinfection Exclusion ss00539 0 0 0 1 0 0 0 0 0 0 Phages, Prophages, Transposable elements Unclassified Subsystem ss00119 5 5 0 1 2 1 1 2 0 0 Phages, Prophages, Transposable elements Unclassified Subsystem ss00275 8 9 8 8 13 16 3 8 9 8 Phages, Prophages, Transposable elements Unclassified Subsystem ss00289 102 85 38 37 52 114 70 109 55 48 Phages, Prophages, Transposable elements Unclassified Subsystem ss00458 136 137 76 85 60 133 72 155 78 67 Phages, Prophages, Transposable elements Unclassified Subsystem ss00790 52 60 32 30 61 104 51 124 57 40 Phages, Prophages, Transposable elements Unclassified Subsystem ss00877 2 2 5 3 0 4 5 9 3 2 Phosphorus Metabolism Unclassified Subsystem ss00249 93 85 102 105 94 166 85 148 101 86 Phosphorus Metabolism Unclassified Subsystem ss00355 11 10 12 13 7 8 5 12 13 14 Phosphorus Metabolism Unclassified Subsystem ss00436 11 9 6 7 5 9 6 12 4 6 Phosphorus Metabolism Unclassified Subsystem ss00846 452 379 204 253 311 530 316 648 334 280 Phosphorus Metabolism Unclassified Subsystem ss00980 1149 975 541 688 893 1531 912 1732 884 745 Phosphorus Metabolism Unclassified Subsystem ss01027 11 8 8 8 5 6 4 10 6 11 Photosynthesis Electron transport and photophosphorylation ss00492 3 11 0 1 7 4 30 64 1 1 Photosynthesis Electron transport and photophosphorylation ss00643 10 10 0 0 1 1 1 7 2 0 Photosynthesis Electron transport and photophosphorylation ss00819 9 11 2 4 11 7 50 159 4 6 Photosynthesis Electron transport and photophosphorylation ss00837 0 0 1 0 0 1 0 1 1 0 Photosynthesis Light-harvesting complexes ss00002 4 2 3 1 5 4 50 105 4 2 Photosynthesis Light-harvesting complexes ss00438 2 3 0 0 1 0 0 0 0 0 Photosynthesis Light-harvesting complexes ss01072 20 20 8 5 5 11 9 16 9 9 Photosynthesis Unclassified Subsystem ss00358 0 0 0 0 2 14 3 6 0 0 Photosynthesis Unclassified Subsystem ss01068 88 65 66 56 91 150 113 177 63 50 Potassium metabolism Unclassified Subsystem ss00749 743 646 414 501 702 1228 746 1347 596 498 Potassium metabolism Unclassified Subsystem ss00916 19 11 1 1 10 19 11 33 1 2 Protein Metabolism Protein biosynthesis ss00017 393 338 217 279 264 465 282 520 414 305 Protein Metabolism Protein biosynthesis ss00018 1 2 2 2 3 4 2 2 2 0 Protein Metabolism Protein biosynthesis ss00033 289 243 122 151 149 288 157 308 192 155 Protein Metabolism Protein biosynthesis ss00058 184 149 94 112 95 178 91 155 128 100 Protein Metabolism Protein biosynthesis ss00126 4 2 0 1 1 2 1 5 2 1 Protein Metabolism Protein biosynthesis ss00187 592 596 291 359 519 903 521 1060 448 395 Protein Metabolism Protein biosynthesis ss00303 0 0 0 0 0 0 0 0 0 0 Protein Metabolism Protein biosynthesis ss00367 1 1 0 0 0 0 0 0 0 0 Protein Metabolism Protein biosynthesis ss00484 18 19 10 12 12 23 18 29 13 9 Protein Metabolism Protein biosynthesis ss00528 35 28 28 27 20 41 19 30 31 28 Protein Metabolism Protein biosynthesis ss00577 106 76 42 50 34 65 43 69 52 40 Protein Metabolism Protein biosynthesis ss00587 849 899 442 511 744 1319 812 1625 665 580 Protein Metabolism Protein biosynthesis ss00762 9 15 6 11 20 25 27 41 10 8 Protein Metabolism Protein biosynthesis ss00765 2 6 2 3 2 6 4 13 2 0 Protein Metabolism Protein biosynthesis ss00784 14 13 5 6 4 9 7 10 9 5 Protein Metabolism Protein biosynthesis ss00825 12 7 6 6 8 12 5 11 6 4 Protein Metabolism Protein biosynthesis ss00854 13 10 9 15 13 28 14 25 17 12 Protein Metabolism Protein biosynthesis ss00859 296 250 119 142 198 333 195 326 161 147 Protein Metabolism Protein biosynthesis ss00874 670 626 281 348 423 761 435 780 417 334 Protein Metabolism Protein biosynthesis ss00883 14 11 15 26 13 15 11 13 25 11 Protein Metabolism Protein biosynthesis ss00887 8 6 3 4 3 5 2 6 5 3 Protein Metabolism Protein biosynthesis ss00950 197 224 97 104 136 231 138 261 121 112 Protein Metabolism Protein degradation ss00093 23 15 21 19 92 137 89 139 32 22 Protein Metabolism Protein degradation ss00369 212 161 99 128 141 262 148 230 144 130 Protein Metabolism Protein degradation ss00548 859 854 430 533 537 1062 684 1229 772 673 Protein Metabolism Protein degradation ss00755 84 59 46 73 81 136 85 180 79 69 Protein Metabolism Protein degradation ss00805 234 202 100 108 94 169 92 168 114 92 Protein Metabolism Protein degradation ss00981 6 3 2 2 3 2 0 2 5 3 Protein Metabolism Protein folding ss00567 2 5 1 4 1 1 1 2 3 3 Protein Metabolism Protein folding ss00718 482 459 252 273 320 570 369 657 344 301 Protein Metabolism Protein folding ss00816 27 24 8 16 9 18 10 17 17 15 Protein Metabolism Protein folding ss00912 53 56 28 34 19 42 29 35 30 30 Protein Metabolism Protein folding ss00971 153 134 83 100 52 127 75 142 113 89 Protein Metabolism Protein processing and modification ss00038 2 0 1 1 1 1 1 0 1 0 Protein Metabolism Protein processing and modification ss00211 83 68 34 41 38 74 49 77 58 39 Protein Metabolism Protein processing and modification ss00740 26 18 14 11 10 17 12 26 15 11 Protein Metabolism Protein processing and modification ss00787 31 37 10 18 29 50 38 59 19 11 Protein Metabolism Protein processing and modification ss01034 91 68 57 52 75 126 80 154 79 63 Protein Metabolism Protein processing and modification ss01092 158 146 81 87 85 151 85 200 125 101 Protein Metabolism Secretion ss00261 43 47 34 47 49 92 35 80 41 32 Protein Metabolism Secretion ss00343 9 9 2 6 3 5 3 7 1 3 Protein Metabolism Secretion ss01039 29 27 24 35 79 128 47 96 35 30 Protein Metabolism Selenoproteins ss00072 14 12 7 9 22 29 18 26 5 10 Protein Metabolism Selenoproteins ss00698 96 96 59 69 84 145 92 168 83 67 Protein Metabolism Selenoproteins ss00845 235 162 108 130 197 288 193 337 186 156 RNA Metabolism RNA processing and modification ss00066 3 3 1 1 3 2 2 4 2 3 RNA Metabolism RNA processing and modification ss00091 119 102 46 54 54 86 54 104 65 58 RNA Metabolism RNA processing and modification ss00213 4 5 2 4 3 4 1 3 1 2 RNA Metabolism RNA processing and modification ss00237 1 2 0 2 0 0 0 0 0 0 RNA Metabolism RNA processing and modification ss00251 761 826 441 526 1572 2408 1413 1987 578 538 RNA Metabolism RNA processing and modification ss00377 13 10 9 15 13 28 14 25 17 12 RNA Metabolism RNA processing and modification ss00389 42 41 18 23 45 75 50 72 32 32 RNA Metabolism RNA processing and modification ss00450 286 288 138 167 251 508 256 487 206 169 RNA Metabolism RNA processing and modification ss00543 283 231 88 107 130 189 145 251 123 117 RNA Metabolism RNA processing and modification ss00571 84 59 30 44 50 77 34 75 50 47 RNA Metabolism RNA processing and modification ss00663 93 91 28 34 61 112 78 138 53 51 RNA Metabolism RNA processing and modification ss00666 0 1 1 1 0 0 1 0 0 1 RNA Metabolism RNA processing and modification ss00798 0 0 0 0 0 0 0 0 0 0 RNA Metabolism RNA processing and modification ss00832 3 3 1 2 2 2 1 3 1 0 RNA Metabolism RNA processing and modification ss00866 1 0 0 0 0 0 1 1 0 0 RNA Metabolism RNA processing and modification ss00879 30 23 14 16 22 32 16 47 12 12 RNA Metabolism RNA processing and modification ss00922 208 174 104 122 215 376 191 349 159 121 RNA Metabolism RNA processing and modification ss00957 287 234 140 159 168 335 207 440 203 197 RNA Metabolism RNA processing and modification ss00982 70 54 29 39 34 66 44 67 52 36 RNA Metabolism RNA processing and modification ss01004 1 3 1 1 0 2 2 3 1 2 RNA Metabolism RNA processing and modification ss01018 105 97 43 48 32 59 33 60 59 47 RNA Metabolism RNA processing and modification ss01064 51 39 20 18 37 50 35 67 25 23 RNA Metabolism Transcription ss00023 4 6 3 5 12 15 10 20 8 4 RNA Metabolism Transcription ss00200 770 755 349 363 507 960 527 1048 530 465 RNA Metabolism Transcription ss00274 1 1 2 1 0 1 0 1 1 0 RNA Metabolism Transcription ss00291 0 0 0 0 1 0 0 0 0 0 RNA Metabolism Transcription ss00388 10 4 7 2 16 36 19 38 7 3 RNA Metabolism Transcription ss00424 5 6 1 2 1 3 1 3 2 1 RNA Metabolism Transcription ss00511 9 6 4 10 10 14 12 32 10 8 RNA Metabolism Transcription ss00538 0 0 0 0 0 0 0 0 0 0 RNA Metabolism Transcription ss00695 0 0 0 1 0 1 0 0 0 0 RNA Metabolism Transcription ss00709 533 534 244 301 445 771 465 831 422 401 RNA Metabolism Transcription ss00737 302 306 221 261 237 482 272 522 360 304 RNA Metabolism Transcription ss00943 1 1 1 1 1 2 1 1 1 0 RNA Metabolism Transcription ss01020 0 0 0 0 0 0 0 0 0 0 RNA Metabolism Unclassified Subsystem ss00978 242 179 195 225 72 136 111 278 230 153 Regulation and Cell signaling Antibacterial peptides ss00461 4 5 3 7 7 17 5 12 2 6 Regulation and Cell signaling Programmed Cell Death and Toxin-antitoxin Systems ss00212 33 42 18 20 16 30 30 70 19 14 Regulation and Cell signaling Programmed Cell Death and Toxin-antitoxin Systems ss00669 6 5 4 3 1 2 0 6 4 3 Regulation and Cell signaling Programmed Cell Death and Toxin-antitoxin Systems ss00869 43 52 39 44 40 72 53 88 50 48 Regulation and Cell signaling Proteolytic pathway ss00230 2 1 3 0 1 1 0 0 0 0 Regulation and Cell signaling Proteolytic pathway ss00242 50 45 23 35 26 49 23 71 40 30 Regulation and Cell signaling Proteolytic pathway ss00701 3 1 1 0 2 8 4 2 4 2 Regulation and Cell signaling Signal transduction in Eukaryotes ss00453 26 34 22 28 25 33 17 19 39 23 Regulation and Cell signaling Unclassified Subsystem ss00239 8 9 3 3 2 5 3 6 5 3 Regulation and Cell signaling Unclassified Subsystem ss00241 90 83 48 52 40 73 42 84 56 44 Regulation and Cell signaling Unclassified Subsystem ss00280 378 298 189 233 516 826 531 924 325 271 Regulation and Cell signaling Unclassified Subsystem ss00425 14 18 24 29 20 33 20 33 28 25 Regulation and Cell signaling Unclassified Subsystem ss00582 100 84 83 90 89 178 78 216 106 77 Regulation and Cell signaling Unclassified Subsystem ss00625 84 71 46 58 70 134 87 157 67 62 Regulation and Cell signaling Unclassified Subsystem ss00702 459 435 256 349 268 471 294 574 409 317 Regulation and Cell signaling Unclassified Subsystem ss00844 139 148 83 95 89 158 102 193 95 81 Regulation and Cell signaling Unclassified Subsystem ss00876 641 543 626 741 528 917 603 1224 795 704 Regulation and Cell signaling Unclassified Subsystem ss00881 44 50 69 79 42 66 62 90 56 62 Regulation and Cell signaling Unclassified Subsystem ss00938 137 127 65 76 92 205 126 234 117 100 Respiration ATP synthases ss00357 74 45 6 5 2 9 2 4 1 3 Respiration ATP synthases ss00446 682 635 243 335 378 651 414 781 411 332 Respiration Electron accepting reactions ss00278 46 51 26 33 13 48 17 28 47 32 Respiration Electron accepting reactions ss00505 63 59 52 66 63 131 45 123 65 52 Respiration Electron accepting reactions ss00834 448 463 271 312 284 584 303 632 382 325 Respiration Electron accepting reactions ss00948 706 521 233 307 227 448 196 454 339 313 Respiration Electron accepting reactions ss01063 114 84 74 78 82 139 73 160 89 75 Respiration Electron donating reactions ss00147 10 5 0 0 1 0 3 0 0 1 Respiration Electron donating reactions ss00247 1152 1036 560 616 764 1398 805 1682 823 669 Respiration Electron donating reactions ss00258 127 137 93 119 124 252 158 298 180 128 Respiration Electron donating reactions ss00318 0 0 0 0 0 0 0 0 0 0 Respiration Electron donating reactions ss00441 185 172 11 16 9 13 7 22 25 15 Respiration Electron donating reactions ss00454 180 138 173 218 177 293 177 312 287 224 Respiration Electron donating reactions ss00485 567 455 69 78 44 68 30 107 142 126 Respiration Electron donating reactions ss00614 1 1 1 1 1 1 0 1 1 0 Respiration Electron donating reactions ss00899 5 4 0 0 0 0 0 0 0 1 Respiration Electron donating reactions ss01017 14 7 8 9 5 10 5 11 6 7 Respiration Electron donating reactions ss01019 12 12 13 12 10 11 9 20 14 10 Respiration Electron donating reactions ss01023 308 221 61 84 35 64 42 89 96 84 Respiration Electron donating reactions ss01041 274 279 256 301 290 526 282 575 389 312 Respiration Sodium Ion-Coupled Energetics ss00983 122 102 54 64 87 148 77 152 78 75 Respiration Unclassified Subsystem ss00130 1 1 0 3 0 2 0 1 0 1 Respiration Unclassified Subsystem ss00208 44 42 31 39 60 102 74 124 57 52 Respiration Unclassified Subsystem ss00268 317 267 149 193 211 362 215 407 228 190 Respiration Unclassified Subsystem ss00308 3 8 1 4 1 4 10 46 2 0 Respiration Unclassified Subsystem ss00401 101 76 53 71 65 136 79 134 87 58 Respiration Unclassified Subsystem ss00557 215 175 60 63 83 130 76 152 71 54 Respiration Unclassified Subsystem ss00568 133 112 64 74 92 163 102 176 120 90 Respiration Unclassified Subsystem ss00590 25 20 16 24 5 9 3 7 25 14 Respiration Unclassified Subsystem ss00617 2 4 2 1 1 3 1 1 3 2 Respiration Unclassified Subsystem ss00804 583 492 343 415 265 497 293 582 496 414 Respiration Unclassified Subsystem ss00999 10 5 0 4 3 8 4 8 2 3 Respiration Unclassified Subsystem ss01055 103 100 18 34 12 25 20 36 39 45 Secondary Metabolism Aromatic amino acids and derivatives ss00366 17 16 14 16 19 24 14 25 16 16 Secondary Metabolism Bacterial cytostatics, differentiation factors and antibiotics ss00128 2 3 3 3 1 3 1 4 4 0 Secondary Metabolism Bacterial cytostatics, differentiation factors and antibiotics ss00223 2 3 2 2 7 25 10 25 3 1 Secondary Metabolism Bacterial cytostatics, differentiation factors and antibiotics ss00653 1 1 0 0 3 8 6 4 1 2 Secondary Metabolism Biologically active compounds in metazoan cell defence and differentiation ss00304 0 0 0 0 0 0 0 0 0 0 Secondary Metabolism Biologically active compounds in metazoan cell defence and differentiation ss00584 115 92 54 81 16 43 18 35 95 86 Secondary Metabolism Biosynthesis of phenylpropanoids ss00031 7 5 5 4 2 6 6 6 7 5 Secondary Metabolism Biosynthesis of phenylpropanoids ss00071 0 0 0 0 0 0 0 0 0 0 Secondary Metabolism Biosynthesis of phenylpropanoids ss00210 5 2 0 3 1 4 2 3 2 0 Secondary Metabolism Biosynthesis of phenylpropanoids ss00285 0 0 0 1 0 0 0 0 0 0 Secondary Metabolism Biosynthesis of phenylpropanoids ss00322 7 5 5 4 2 6 6 6 7 5 Secondary Metabolism Biosynthesis of phenylpropanoids ss00443 38 38 28 34 25 42 30 56 38 20 Secondary Metabolism Biosynthesis of phenylpropanoids ss00516 58 36 33 45 156 263 156 271 59 52 Secondary Metabolism Biosynthesis of phenylpropanoids ss00696 1 1 0 1 0 1 0 1 1 0 Secondary Metabolism Biosynthesis of phenylpropanoids ss00761 0 0 0 0 0 0 1 0 0 0 Secondary Metabolism Biosynthesis of phenylpropanoids ss00813 9 7 13 16 36 60 31 76 16 17 Secondary Metabolism Biosynthesis of phenylpropanoids ss00817 0 0 0 0 0 0 0 0 0 0 Secondary Metabolism Biosynthesis of phenylpropanoids ss00947 15 5 5 4 6 12 16 20 8 5 Secondary Metabolism Lipid-derived mediators ss00354 0 0 0 1 1 1 1 1 1 1 Secondary Metabolism Plant Alkaloids ss00530 21 24 9 17 10 15 20 25 15 14 Secondary Metabolism Plant Hormones ss00166 272 267 174 218 178 350 228 377 261 229 Secondary Metabolism Plant Hormones ss00197 201 172 91 114 131 227 154 268 140 125 Secondary Metabolism Plant Octadecanoids ss00756 1 0 0 1 0 0 1 0 2 0 Stress Response Acid stress ss00973 42 39 21 20 9 19 11 16 28 17 Stress Response Detoxification ss01046 7 7 2 3 6 11 8 14 8 4 Stress Response Osmotic stress ss00101 8 7 3 9 2 15 3 5 8 0 Stress Response Osmotic stress ss00115 78 57 55 82 45 75 44 76 80 72 Stress Response Osmotic stress ss00510 14 13 3 3 5 6 3 4 3 2 Stress Response Osmotic stress ss00699 229 203 153 203 268 473 268 526 214 163 Stress Response Oxidative stress ss00254 73 63 56 73 77 139 61 130 75 74 Stress Response Oxidative stress ss00398 96 92 43 45 23 36 22 58 59 39 Stress Response Oxidative stress ss00602 342 319 227 299 254 502 319 564 308 262 Stress Response Oxidative stress ss00722 223 199 87 128 155 249 137 257 139 126 Stress Response Oxidative stress ss00923 142 112 75 84 119 196 150 246 99 89 Stress Response Oxidative stress ss01043 101 94 78 95 58 110 56 126 72 59 Stress Response Unclassified Subsystem ss00013 325 298 169 212 242 418 211 406 260 222 Stress Response Unclassified Subsystem ss00180 43 35 16 25 38 53 51 56 49 31 Stress Response Unclassified Subsystem ss00234 237 203 113 150 293 473 267 493 156 121 Stress Response Unclassified Subsystem ss00256 879 786 460 560 733 1231 711 1341 630 544 Stress Response Unclassified Subsystem ss00464 18 17 19 11 21 33 26 38 29 15 Stress Response Unclassified Subsystem ss00486 20 19 8 11 19 30 25 43 25 13 Stress Response Unclassified Subsystem ss00671 254 274 290 324 403 719 515 870 427 337 Stress Response Unclassified Subsystem ss00676 161 152 68 88 122 185 124 226 125 93 Stress Response Unclassified Subsystem ss00732 0 0 0 0 0 1 0 0 0 0 Sulfur Metabolism Inorganic sulfur assimilation ss00339 296 281 184 198 271 486 279 552 272 219 Sulfur Metabolism Organic sulfur assimilation ss00269 193 158 209 259 158 237 147 251 252 246 Sulfur Metabolism Organic sulfur assimilation ss00432 157 149 108 157 269 396 254 488 161 130 Sulfur Metabolism Organic sulfur assimilation ss00576 98 87 87 105 101 179 93 189 126 122 Sulfur Metabolism Organic sulfur assimilation ss00607 1 0 0 2 0 2 2 8 3 1 Sulfur Metabolism Organic sulfur assimilation ss00924 6 5 8 14 9 9 7 9 14 8 Sulfur Metabolism Unclassified Subsystem ss00009 112 79 3 2 1 4 0 1 3 3 Sulfur Metabolism Unclassified Subsystem ss00629 159 134 95 101 127 195 118 235 114 108 Sulfur Metabolism Unclassified Subsystem ss00788 272 233 131 178 113 215 124 231 194 173 Sulfur Metabolism Unclassified Subsystem ss01088 77 66 79 79 30 57 32 74 89 89 Unclassified Subsystem Unclassified Subsystem ss00000 15 12 8 13 55 80 47 78 13 14 Unclassified Subsystem Unclassified Subsystem ss00006 5 5 7 7 4 12 4 5 14 11 Unclassified Subsystem Unclassified Subsystem ss00007 1 1 0 0 1 0 0 1 1 0 Unclassified Subsystem Unclassified Subsystem ss00010 130 103 33 37 85 140 93 176 52 46 Unclassified Subsystem Unclassified Subsystem ss00012 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00014 81 79 54 71 68 137 58 130 66 64 Unclassified Subsystem Unclassified Subsystem ss00020 15 15 11 18 23 36 14 30 16 13 Unclassified Subsystem Unclassified Subsystem ss00021 83 73 32 38 45 94 50 97 45 43 Unclassified Subsystem Unclassified Subsystem ss00022 292 241 130 142 203 380 220 432 179 141 Unclassified Subsystem Unclassified Subsystem ss00025 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00028 340 320 200 248 252 408 248 457 258 217 Unclassified Subsystem Unclassified Subsystem ss00029 315 238 158 168 165 244 138 249 177 142 Unclassified Subsystem Unclassified Subsystem ss00032 18 16 10 9 12 20 13 20 10 14 Unclassified Subsystem Unclassified Subsystem ss00036 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00039 33 26 34 36 34 90 37 77 34 24 Unclassified Subsystem Unclassified Subsystem ss00040 8 12 8 16 11 22 13 16 17 12 Unclassified Subsystem Unclassified Subsystem ss00041 0 0 0 0 1 3 0 1 0 0 Unclassified Subsystem Unclassified Subsystem ss00044 22 31 18 40 21 65 27 44 23 30 Unclassified Subsystem Unclassified Subsystem ss00046 14 22 10 13 39 56 29 50 22 16 Unclassified Subsystem Unclassified Subsystem ss00047 3 4 2 3 1 1 1 3 6 3 Unclassified Subsystem Unclassified Subsystem ss00051 0 1 1 0 2 4 2 4 2 1 Unclassified Subsystem Unclassified Subsystem ss00062 0 1 1 2 2 6 1 3 4 3 Unclassified Subsystem Unclassified Subsystem ss00064 145 135 60 74 56 127 66 112 79 65 Unclassified Subsystem Unclassified Subsystem ss00068 64 50 32 49 98 158 98 174 61 41 Unclassified Subsystem Unclassified Subsystem ss00073 911 763 490 629 760 1309 758 1339 776 662 Unclassified Subsystem Unclassified Subsystem ss00074 1 2 1 1 2 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00077 17 12 6 9 15 19 13 20 15 8 Unclassified Subsystem Unclassified Subsystem ss00078 9 9 9 12 5 8 5 11 14 14 Unclassified Subsystem Unclassified Subsystem ss00079 38 27 15 14 25 47 17 41 16 20 Unclassified Subsystem Unclassified Subsystem ss00080 65 38 28 23 37 69 44 91 48 40 Unclassified Subsystem Unclassified Subsystem ss00081 13 5 5 4 5 11 17 23 7 4 Unclassified Subsystem Unclassified Subsystem ss00083 12 12 7 7 5 7 5 8 6 5 Unclassified Subsystem Unclassified Subsystem ss00094 0 1 0 1 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00095 334 268 147 168 161 264 146 290 178 142 Unclassified Subsystem Unclassified Subsystem ss00097 42 44 23 30 27 33 20 47 26 27 Unclassified Subsystem Unclassified Subsystem ss00098 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00100 9 7 3 1 1 2 1 3 1 2 Unclassified Subsystem Unclassified Subsystem ss00102 0 1 1 1 1 3 2 1 1 1 Unclassified Subsystem Unclassified Subsystem ss00108 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00110 11 7 5 9 10 25 21 42 14 5 Unclassified Subsystem Unclassified Subsystem ss00116 5 5 4 3 3 5 1 5 7 6 Unclassified Subsystem Unclassified Subsystem ss00123 30 20 10 20 15 31 14 23 23 18 Unclassified Subsystem Unclassified Subsystem ss00127 42 33 13 18 17 30 21 29 22 16 Unclassified Subsystem Unclassified Subsystem ss00131 13 7 15 11 9 24 11 23 17 16 Unclassified Subsystem Unclassified Subsystem ss00137 43 39 28 31 43 69 50 73 41 36 Unclassified Subsystem Unclassified Subsystem ss00138 12 9 6 5 19 52 34 52 10 8 Unclassified Subsystem Unclassified Subsystem ss00140 22 18 5 9 4 10 7 9 12 16 Unclassified Subsystem Unclassified Subsystem ss00141 31 24 20 21 12 12 10 14 21 21 Unclassified Subsystem Unclassified Subsystem ss00148 96 74 56 60 74 128 71 154 77 66 Unclassified Subsystem Unclassified Subsystem ss00150 120 98 84 103 76 127 82 151 128 98 Unclassified Subsystem Unclassified Subsystem ss00154 45 43 65 74 49 73 42 96 63 59 Unclassified Subsystem Unclassified Subsystem ss00158 112 88 62 72 56 93 43 88 74 68 Unclassified Subsystem Unclassified Subsystem ss00160 3 3 1 2 0 1 1 1 0 0 Unclassified Subsystem Unclassified Subsystem ss00164 13 8 3 4 5 5 3 6 7 8 Unclassified Subsystem Unclassified Subsystem ss00165 30 22 13 24 33 42 29 42 19 12 Unclassified Subsystem Unclassified Subsystem ss00168 47 36 29 38 23 54 33 37 33 23 Unclassified Subsystem Unclassified Subsystem ss00173 633 600 322 396 620 1042 618 1112 544 445 Unclassified Subsystem Unclassified Subsystem ss00182 19 17 14 18 24 38 25 35 20 19 Unclassified Subsystem Unclassified Subsystem ss00184 7 6 4 6 11 18 11 15 9 6 Unclassified Subsystem Unclassified Subsystem ss00192 132 115 74 72 95 164 108 174 97 72 Unclassified Subsystem Unclassified Subsystem ss00195 13 16 33 35 31 50 26 61 35 27 Unclassified Subsystem Unclassified Subsystem ss00198 0 0 0 0 0 0 1 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00202 1017 841 477 579 815 1367 803 1489 715 566 Unclassified Subsystem Unclassified Subsystem ss00203 1 3 1 2 12 28 15 37 3 3 Unclassified Subsystem Unclassified Subsystem ss00205 20 18 19 13 16 30 14 24 12 16 Unclassified Subsystem Unclassified Subsystem ss00214 3 6 4 5 14 23 15 23 5 4 Unclassified Subsystem Unclassified Subsystem ss00215 5 4 0 2 1 4 0 5 2 3 Unclassified Subsystem Unclassified Subsystem ss00217 747 598 312 348 273 476 240 470 372 299 Unclassified Subsystem Unclassified Subsystem ss00225 179 162 97 117 103 159 86 139 117 106 Unclassified Subsystem Unclassified Subsystem ss00228 926 773 390 479 504 846 441 860 539 408 Unclassified Subsystem Unclassified Subsystem ss00233 9 6 0 1 0 2 1 1 1 1 Unclassified Subsystem Unclassified Subsystem ss00236 12 11 9 9 47 60 45 90 21 14 Unclassified Subsystem Unclassified Subsystem ss00245 5 2 2 1 1 1 0 2 2 2 Unclassified Subsystem Unclassified Subsystem ss00257 6 6 7 10 7 13 8 18 13 14 Unclassified Subsystem Unclassified Subsystem ss00260 1 2 1 1 0 1 0 0 1 1 Unclassified Subsystem Unclassified Subsystem ss00264 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00271 3 7 0 1 1 6 1 2 2 0 Unclassified Subsystem Unclassified Subsystem ss00282 54 46 31 35 30 59 33 69 38 37 Unclassified Subsystem Unclassified Subsystem ss00284 29 33 15 16 17 27 14 28 20 16 Unclassified Subsystem Unclassified Subsystem ss00287 0 0 0 0 0 1 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00288 0 1 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00292 10 3 1 2 4 4 2 5 3 4 Unclassified Subsystem Unclassified Subsystem ss00297 11 8 4 3 7 10 6 12 7 5 Unclassified Subsystem Unclassified Subsystem ss00298 0 1 0 1 0 0 0 2 0 0 Unclassified Subsystem Unclassified Subsystem ss00299 14 13 5 6 7 11 4 11 5 10 Unclassified Subsystem Unclassified Subsystem ss00301 1 2 1 0 0 0 0 1 1 1 Unclassified Subsystem Unclassified Subsystem ss00305 8 8 23 27 22 45 30 50 35 20 Unclassified Subsystem Unclassified Subsystem ss00312 23 14 3 5 7 17 7 14 9 9 Unclassified Subsystem Unclassified Subsystem ss00324 80 88 58 109 101 147 93 198 98 93 Unclassified Subsystem Unclassified Subsystem ss00325 68 50 45 57 47 85 47 69 63 47 Unclassified Subsystem Unclassified Subsystem ss00327 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00331 311 244 141 165 232 457 261 442 217 176 Unclassified Subsystem Unclassified Subsystem ss00333 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00334 6 5 2 0 6 7 4 9 3 5 Unclassified Subsystem Unclassified Subsystem ss00336 181 174 111 133 241 457 227 474 197 145 Unclassified Subsystem Unclassified Subsystem ss00340 11 10 5 3 3 6 6 2 4 7 Unclassified Subsystem Unclassified Subsystem ss00344 4 7 5 5 5 7 3 8 8 9 Unclassified Subsystem Unclassified Subsystem ss00347 5 4 2 3 3 2 2 7 2 3 Unclassified Subsystem Unclassified Subsystem ss00353 12 10 5 3 2 7 1 2 6 6 Unclassified Subsystem Unclassified Subsystem ss00364 132 109 46 56 43 80 55 112 60 54 Unclassified Subsystem Unclassified Subsystem ss00365 138 107 79 94 154 258 171 331 95 72 Unclassified Subsystem Unclassified Subsystem ss00370 316 273 212 236 203 367 215 424 259 235 Unclassified Subsystem Unclassified Subsystem ss00371 63 58 28 37 37 60 31 61 36 31 Unclassified Subsystem Unclassified Subsystem ss00373 93 78 52 51 39 59 30 48 60 50 Unclassified Subsystem Unclassified Subsystem ss00375 11 9 3 4 4 12 7 14 8 7 Unclassified Subsystem Unclassified Subsystem ss00376 74 65 44 52 71 131 46 125 73 55 Unclassified Subsystem Unclassified Subsystem ss00378 246 217 129 156 87 131 97 235 170 142 Unclassified Subsystem Unclassified Subsystem ss00384 83 51 22 28 15 24 12 12 23 26 Unclassified Subsystem Unclassified Subsystem ss00387 7 6 2 3 2 5 2 4 2 1 Unclassified Subsystem Unclassified Subsystem ss00390 1 1 1 0 1 1 0 1 1 0 Unclassified Subsystem Unclassified Subsystem ss00393 32 24 15 23 16 20 14 26 13 19 Unclassified Subsystem Unclassified Subsystem ss00395 4 4 2 3 9 7 3 9 3 2 Unclassified Subsystem Unclassified Subsystem ss00396 18 27 18 17 68 98 51 99 25 15 Unclassified Subsystem Unclassified Subsystem ss00397 16 21 15 25 29 41 29 52 32 21 Unclassified Subsystem Unclassified Subsystem ss00400 8 5 3 4 4 5 3 5 3 3 Unclassified Subsystem Unclassified Subsystem ss00402 82 71 32 40 30 57 34 55 45 34 Unclassified Subsystem Unclassified Subsystem ss00403 109 94 48 44 26 56 26 50 56 62 Unclassified Subsystem Unclassified Subsystem ss00404 81 78 48 54 48 87 45 78 64 56 Unclassified Subsystem Unclassified Subsystem ss00405 25 20 13 13 14 26 15 23 15 10 Unclassified Subsystem Unclassified Subsystem ss00408 2 0 1 2 2 3 3 6 1 1 Unclassified Subsystem Unclassified Subsystem ss00410 69 67 48 57 65 117 62 121 71 65 Unclassified Subsystem Unclassified Subsystem ss00411 100 85 89 95 81 142 108 190 98 94 Unclassified Subsystem Unclassified Subsystem ss00414 3 8 5 5 25 41 15 34 8 8 Unclassified Subsystem Unclassified Subsystem ss00416 37 26 13 14 9 11 18 28 11 21 Unclassified Subsystem Unclassified Subsystem ss00417 15 18 10 12 17 20 58 124 12 11 Unclassified Subsystem Unclassified Subsystem ss00420 15 8 10 9 73 102 72 108 12 10 Unclassified Subsystem Unclassified Subsystem ss00428 0 0 0 0 0 0 0 0 0 1 Unclassified Subsystem Unclassified Subsystem ss00429 25 20 13 20 9 18 17 35 28 22 Unclassified Subsystem Unclassified Subsystem ss00430 3 4 1 4 4 13 4 13 5 1 Unclassified Subsystem Unclassified Subsystem ss00431 13 19 4 4 5 10 2 4 10 3 Unclassified Subsystem Unclassified Subsystem ss00439 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00444 358 304 169 175 266 435 276 479 240 197 Unclassified Subsystem Unclassified Subsystem ss00445 1 3 1 2 3 9 10 14 3 4 Unclassified Subsystem Unclassified Subsystem ss00448 131 111 95 104 193 333 173 348 130 104 Unclassified Subsystem Unclassified Subsystem ss00452 7 5 2 6 3 7 9 8 3 7 Unclassified Subsystem Unclassified Subsystem ss00455 275 236 134 139 130 232 123 253 175 144 Unclassified Subsystem Unclassified Subsystem ss00467 13 17 5 13 4 9 2 9 9 8 Unclassified Subsystem Unclassified Subsystem ss00472 21 15 10 16 12 29 16 25 10 8 Unclassified Subsystem Unclassified Subsystem ss00474 300 235 165 188 173 260 181 309 194 182 Unclassified Subsystem Unclassified Subsystem ss00476 119 109 75 96 77 148 91 150 120 105 Unclassified Subsystem Unclassified Subsystem ss00480 12 10 3 4 1 6 4 9 2 3 Unclassified Subsystem Unclassified Subsystem ss00481 2 2 0 1 0 0 0 1 2 1 Unclassified Subsystem Unclassified Subsystem ss00482 2 1 0 0 1 1 0 1 3 2 Unclassified Subsystem Unclassified Subsystem ss00488 1 2 0 0 5 5 5 1 1 0 Unclassified Subsystem Unclassified Subsystem ss00489 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00493 27 19 15 15 13 23 15 27 12 15 Unclassified Subsystem Unclassified Subsystem ss00501 5 3 0 1 2 4 4 4 1 2 Unclassified Subsystem Unclassified Subsystem ss00503 19 16 5 11 12 24 14 20 7 11 Unclassified Subsystem Unclassified Subsystem ss00506 168 161 91 109 83 147 83 138 112 97 Unclassified Subsystem Unclassified Subsystem ss00507 4 3 2 1 0 1 1 2 1 1 Unclassified Subsystem Unclassified Subsystem ss00514 23 19 9 10 6 17 7 18 11 9 Unclassified Subsystem Unclassified Subsystem ss00518 1 1 0 1 1 1 4 2 1 1 Unclassified Subsystem Unclassified Subsystem ss00519 0 0 0 0 0 0 0 1 0 0 Unclassified Subsystem Unclassified Subsystem ss00520 51 42 20 18 33 59 20 57 24 21 Unclassified Subsystem Unclassified Subsystem ss00521 3 4 3 4 3 4 3 3 4 3 Unclassified Subsystem Unclassified Subsystem ss00522 60 45 46 64 72 117 60 86 93 68 Unclassified Subsystem Unclassified Subsystem ss00523 14 13 2 4 6 15 4 10 6 4 Unclassified Subsystem Unclassified Subsystem ss00532 15 9 4 3 7 11 1 4 6 4 Unclassified Subsystem Unclassified Subsystem ss00533 20 13 0 0 4 10 7 12 0 2 Unclassified Subsystem Unclassified Subsystem ss00534 15 10 2 1 1 1 0 4 3 1 Unclassified Subsystem Unclassified Subsystem ss00535 143 116 90 91 88 146 101 164 90 70 Unclassified Subsystem Unclassified Subsystem ss00545 0 0 2 5 0 1 0 0 2 1 Unclassified Subsystem Unclassified Subsystem ss00549 9 4 2 5 6 11 4 13 4 2 Unclassified Subsystem Unclassified Subsystem ss00551 14 12 1 1 0 0 0 2 1 1 Unclassified Subsystem Unclassified Subsystem ss00554 6 6 13 19 16 14 17 37 8 8 Unclassified Subsystem Unclassified Subsystem ss00555 4 8 2 4 2 4 2 2 3 3 Unclassified Subsystem Unclassified Subsystem ss00559 4 2 0 0 1 1 1 3 0 0 Unclassified Subsystem Unclassified Subsystem ss00560 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00561 1 1 0 0 0 0 0 1 0 0 Unclassified Subsystem Unclassified Subsystem ss00562 2 3 7 3 5 5 1 2 1 0 Unclassified Subsystem Unclassified Subsystem ss00563 1 1 1 1 1 1 1 2 1 0 Unclassified Subsystem Unclassified Subsystem ss00564 137 115 80 80 69 121 81 164 101 75 Unclassified Subsystem Unclassified Subsystem ss00565 15 8 6 5 5 22 8 16 6 5 Unclassified Subsystem Unclassified Subsystem ss00566 2 2 1 3 3 4 2 5 1 2 Unclassified Subsystem Unclassified Subsystem ss00570 20 15 13 15 25 30 17 36 19 18 Unclassified Subsystem Unclassified Subsystem ss00573 41 31 6 9 5 14 9 19 12 13 Unclassified Subsystem Unclassified Subsystem ss00575 127 88 63 84 126 229 104 243 96 78 Unclassified Subsystem Unclassified Subsystem ss00578 214 197 111 128 119 209 119 244 144 133 Unclassified Subsystem Unclassified Subsystem ss00579 30 21 16 28 35 61 34 55 26 22 Unclassified Subsystem Unclassified Subsystem ss00583 27 26 11 19 16 22 13 27 19 15 Unclassified Subsystem Unclassified Subsystem ss00586 96 73 45 59 63 104 67 125 60 44 Unclassified Subsystem Unclassified Subsystem ss00591 9 8 11 8 15 23 17 48 14 14 Unclassified Subsystem Unclassified Subsystem ss00593 13 10 3 4 4 10 6 10 3 7 Unclassified Subsystem Unclassified Subsystem ss00595 0 0 0 0 0 0 0 0 0 1 Unclassified Subsystem Unclassified Subsystem ss00597 7 5 5 7 7 10 4 8 5 4 Unclassified Subsystem Unclassified Subsystem ss00603 2 1 0 0 0 0 2 1 1 2 Unclassified Subsystem Unclassified Subsystem ss00605 363 297 245 256 321 558 302 534 331 287 Unclassified Subsystem Unclassified Subsystem ss00608 26 22 21 32 63 126 52 112 27 19 Unclassified Subsystem Unclassified Subsystem ss00610 23 9 7 8 9 9 7 20 10 6 Unclassified Subsystem Unclassified Subsystem ss00616 162 131 95 112 165 275 152 267 124 107 Unclassified Subsystem Unclassified Subsystem ss00622 162 153 124 166 126 222 120 234 155 145 Unclassified Subsystem Unclassified Subsystem ss00624 112 98 51 62 61 103 64 117 80 60 Unclassified Subsystem Unclassified Subsystem ss00626 140 118 70 99 95 154 100 156 116 74 Unclassified Subsystem Unclassified Subsystem ss00627 15 12 7 8 6 12 6 14 12 6 Unclassified Subsystem Unclassified Subsystem ss00636 22 15 77 86 11 30 22 41 51 54 Unclassified Subsystem Unclassified Subsystem ss00637 11 10 6 3 5 9 4 6 3 2 Unclassified Subsystem Unclassified Subsystem ss00639 9 5 1 3 6 7 4 9 6 5 Unclassified Subsystem Unclassified Subsystem ss00647 158 144 50 74 96 176 109 155 96 77 Unclassified Subsystem Unclassified Subsystem ss00648 15 11 7 9 10 14 11 14 7 8 Unclassified Subsystem Unclassified Subsystem ss00650 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00655 483 405 464 518 324 580 386 732 564 441 Unclassified Subsystem Unclassified Subsystem ss00661 10 4 0 0 2 1 1 1 1 0 Unclassified Subsystem Unclassified Subsystem ss00667 7 6 4 5 7 7 6 11 5 5 Unclassified Subsystem Unclassified Subsystem ss00670 491 410 447 493 580 1019 626 1221 521 416 Unclassified Subsystem Unclassified Subsystem ss00672 15 14 2 4 15 24 18 31 7 8 Unclassified Subsystem Unclassified Subsystem ss00677 0 0 0 0 0 0 0 1 0 1 Unclassified Subsystem Unclassified Subsystem ss00678 130 99 74 99 68 117 58 113 94 72 Unclassified Subsystem Unclassified Subsystem ss00682 435 393 296 341 218 366 217 419 328 296 Unclassified Subsystem Unclassified Subsystem ss00684 67 54 35 53 76 123 81 138 66 65 Unclassified Subsystem Unclassified Subsystem ss00686 1 0 0 0 2 2 3 6 1 1 Unclassified Subsystem Unclassified Subsystem ss00687 20 24 20 38 4 15 3 14 31 19 Unclassified Subsystem Unclassified Subsystem ss00688 12 7 10 9 14 16 12 16 9 6 Unclassified Subsystem Unclassified Subsystem ss00691 2 2 1 1 1 3 2 4 1 2 Unclassified Subsystem Unclassified Subsystem ss00692 107 91 44 52 78 111 72 152 65 56 Unclassified Subsystem Unclassified Subsystem ss00704 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00706 37 49 54 52 119 212 126 242 70 64 Unclassified Subsystem Unclassified Subsystem ss00707 58 34 47 39 22 36 27 35 38 58 Unclassified Subsystem Unclassified Subsystem ss00710 7 7 5 4 3 4 1 3 7 5 Unclassified Subsystem Unclassified Subsystem ss00721 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00723 6 5 3 2 22 36 22 29 2 5 Unclassified Subsystem Unclassified Subsystem ss00729 53 54 14 18 22 38 31 62 31 21 Unclassified Subsystem Unclassified Subsystem ss00739 3 1 0 2 0 1 1 3 2 0 Unclassified Subsystem Unclassified Subsystem ss00743 173 160 80 92 90 153 75 162 117 88 Unclassified Subsystem Unclassified Subsystem ss00745 51 46 22 33 27 54 26 52 39 29 Unclassified Subsystem Unclassified Subsystem ss00750 160 126 68 93 68 111 65 137 89 77 Unclassified Subsystem Unclassified Subsystem ss00751 396 363 197 240 246 364 228 404 280 231 Unclassified Subsystem Unclassified Subsystem ss00754 95 96 58 77 107 144 99 163 88 85 Unclassified Subsystem Unclassified Subsystem ss00767 2 3 1 1 4 4 2 1 0 1 Unclassified Subsystem Unclassified Subsystem ss00769 6 7 2 4 3 4 1 4 10 4 Unclassified Subsystem Unclassified Subsystem ss00770 316 286 112 155 107 217 114 215 149 130 Unclassified Subsystem Unclassified Subsystem ss00773 2 3 3 1 3 3 1 3 4 1 Unclassified Subsystem Unclassified Subsystem ss00776 1 1 0 0 1 1 0 1 0 0 Unclassified Subsystem Unclassified Subsystem ss00777 200 163 88 105 101 178 100 168 123 88 Unclassified Subsystem Unclassified Subsystem ss00780 78 70 38 41 35 65 42 71 49 39 Unclassified Subsystem Unclassified Subsystem ss00789 37 44 28 45 41 82 43 79 49 38 Unclassified Subsystem Unclassified Subsystem ss00791 121 105 72 82 55 102 54 107 88 62 Unclassified Subsystem Unclassified Subsystem ss00792 17 10 15 22 5 11 6 13 12 21 Unclassified Subsystem Unclassified Subsystem ss00794 99 91 47 52 81 146 92 187 89 75 Unclassified Subsystem Unclassified Subsystem ss00796 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00797 113 100 53 73 51 92 54 109 76 65 Unclassified Subsystem Unclassified Subsystem ss00801 2 2 1 1 0 0 1 1 0 1 Unclassified Subsystem Unclassified Subsystem ss00803 81 60 31 34 29 59 36 57 39 39 Unclassified Subsystem Unclassified Subsystem ss00806 5 5 3 3 5 6 12 18 4 3 Unclassified Subsystem Unclassified Subsystem ss00807 50 40 27 30 20 40 23 46 29 28 Unclassified Subsystem Unclassified Subsystem ss00809 3 6 2 2 3 5 3 5 4 2 Unclassified Subsystem Unclassified Subsystem ss00810 2 2 3 4 0 2 1 2 5 2 Unclassified Subsystem Unclassified Subsystem ss00811 2 0 3 3 2 2 5 3 1 1 Unclassified Subsystem Unclassified Subsystem ss00814 178 158 94 115 120 227 119 206 143 133 Unclassified Subsystem Unclassified Subsystem ss00815 314 283 189 215 230 395 216 416 288 223 Unclassified Subsystem Unclassified Subsystem ss00823 8 11 14 18 25 47 25 57 19 16 Unclassified Subsystem Unclassified Subsystem ss00824 95 79 46 56 58 120 56 91 57 62 Unclassified Subsystem Unclassified Subsystem ss00831 8 11 4 4 3 7 3 10 7 9 Unclassified Subsystem Unclassified Subsystem ss00839 7 6 4 2 2 4 3 3 5 3 Unclassified Subsystem Unclassified Subsystem ss00841 27 11 29 31 27 79 17 36 32 19 Unclassified Subsystem Unclassified Subsystem ss00851 47 57 59 57 31 71 34 56 71 67 Unclassified Subsystem Unclassified Subsystem ss00852 277 236 100 124 204 397 245 453 199 192 Unclassified Subsystem Unclassified Subsystem ss00856 22 13 20 16 17 24 8 21 16 13 Unclassified Subsystem Unclassified Subsystem ss00857 8 5 3 5 9 27 15 37 11 8 Unclassified Subsystem Unclassified Subsystem ss00865 10 12 6 6 3 7 3 7 6 4 Unclassified Subsystem Unclassified Subsystem ss00867 134 106 60 80 62 115 64 115 70 73 Unclassified Subsystem Unclassified Subsystem ss00870 4 2 1 1 0 1 2 1 1 1 Unclassified Subsystem Unclassified Subsystem ss00871 5 4 5 4 3 5 2 4 2 3 Unclassified Subsystem Unclassified Subsystem ss00880 58 50 33 32 52 73 49 96 41 41 Unclassified Subsystem Unclassified Subsystem ss00889 127 102 56 68 66 95 52 112 68 47 Unclassified Subsystem Unclassified Subsystem ss00892 19 21 12 14 29 62 31 74 21 13 Unclassified Subsystem Unclassified Subsystem ss00903 1 1 1 0 1 0 0 0 0 1 Unclassified Subsystem Unclassified Subsystem ss00905 30 19 31 28 15 35 22 47 29 18 Unclassified Subsystem Unclassified Subsystem ss00907 53 42 19 16 12 23 12 28 31 22 Unclassified Subsystem Unclassified Subsystem ss00921 52 42 17 21 31 50 33 44 39 19 Unclassified Subsystem Unclassified Subsystem ss00926 76 58 35 46 43 62 42 82 44 33 Unclassified Subsystem Unclassified Subsystem ss00928 16 10 6 9 8 11 7 13 9 8 Unclassified Subsystem Unclassified Subsystem ss00934 109 90 104 133 160 271 195 379 115 96 Unclassified Subsystem Unclassified Subsystem ss00936 3 2 1 1 0 0 1 1 1 1 Unclassified Subsystem Unclassified Subsystem ss00941 194 165 91 106 145 246 140 251 146 105 Unclassified Subsystem Unclassified Subsystem ss00953 39 29 29 34 30 69 32 62 42 34 Unclassified Subsystem Unclassified Subsystem ss00955 0 0 0 0 0 0 0 1 0 0 Unclassified Subsystem Unclassified Subsystem ss00960 40 36 22 20 21 41 16 40 35 25 Unclassified Subsystem Unclassified Subsystem ss00961 181 169 94 110 192 344 211 330 143 119 Unclassified Subsystem Unclassified Subsystem ss00962 595 542 304 329 213 453 280 554 433 365 Unclassified Subsystem Unclassified Subsystem ss00964 4 2 0 0 1 0 0 0 2 0 Unclassified Subsystem Unclassified Subsystem ss00965 92 81 64 72 65 126 78 143 85 64 Unclassified Subsystem Unclassified Subsystem ss00966 7 5 2 4 21 36 26 30 6 7 Unclassified Subsystem Unclassified Subsystem ss00967 0 0 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss00984 24 21 9 11 13 18 9 19 7 6 Unclassified Subsystem Unclassified Subsystem ss00985 21 33 18 15 26 45 30 56 24 21 Unclassified Subsystem Unclassified Subsystem ss00992 10 9 6 7 4 10 5 6 3 8 Unclassified Subsystem Unclassified Subsystem ss00997 155 139 192 248 82 130 73 109 231 171 Unclassified Subsystem Unclassified Subsystem ss01000 37 32 14 18 24 38 21 41 26 17 Unclassified Subsystem Unclassified Subsystem ss01001 223 187 96 132 108 223 135 248 121 112 Unclassified Subsystem Unclassified Subsystem ss01003 80 67 37 44 38 57 35 70 48 31 Unclassified Subsystem Unclassified Subsystem ss01007 33 20 12 13 45 70 32 49 19 15 Unclassified Subsystem Unclassified Subsystem ss01008 23 25 12 12 7 9 9 15 18 16 Unclassified Subsystem Unclassified Subsystem ss01010 26 19 16 18 11 16 11 10 18 14 Unclassified Subsystem Unclassified Subsystem ss01012 36 38 15 19 27 37 22 34 20 16 Unclassified Subsystem Unclassified Subsystem ss01016 18 18 6 7 7 7 4 8 10 4 Unclassified Subsystem Unclassified Subsystem ss01021 1 1 0 1 0 1 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss01024 194 166 101 127 131 229 147 252 138 107 Unclassified Subsystem Unclassified Subsystem ss01028 22 17 11 15 59 89 46 83 24 14 Unclassified Subsystem Unclassified Subsystem ss01033 191 171 102 106 131 252 138 268 136 122 Unclassified Subsystem Unclassified Subsystem ss01036 96 90 43 48 65 131 69 123 64 55 Unclassified Subsystem Unclassified Subsystem ss01037 60 59 81 84 86 147 87 140 131 83 Unclassified Subsystem Unclassified Subsystem ss01042 0 1 0 0 0 0 0 0 0 0 Unclassified Subsystem Unclassified Subsystem ss01047 43 43 24 28 28 53 29 57 27 23 Unclassified Subsystem Unclassified Subsystem ss01051 23 24 16 19 10 20 15 19 15 9 Unclassified Subsystem Unclassified Subsystem ss01054 44 20 13 15 7 10 7 22 22 13 Unclassified Subsystem Unclassified Subsystem ss01057 0 0 0 0 0 1 0 1 0 0 Unclassified Subsystem Unclassified Subsystem ss01066 725 680 282 336 309 561 317 610 361 299 Unclassified Subsystem Unclassified Subsystem ss01067 32 26 25 24 17 34 31 45 34 21 Unclassified Subsystem Unclassified Subsystem ss01071 112 91 70 88 107 199 112 191 74 83 Unclassified Subsystem Unclassified Subsystem ss01077 102 84 47 59 61 89 58 107 68 49 Unclassified Subsystem Unclassified Subsystem ss01080 53 49 20 25 8 31 6 21 27 30 Unclassified Subsystem Unclassified Subsystem ss01082 1 1 0 0 0 0 2 0 0 0 Unclassified Subsystem Unclassified Subsystem ss01083 35 42 39 48 19 40 35 57 49 49 Unclassified Subsystem Unclassified Subsystem ss01086 34 28 7 9 7 10 4 16 9 12 Unclassified Subsystem Unclassified Subsystem ss01089 9 3 2 5 2 7 0 5 6 5 Virulence Adhesion ss00057 1 2 2 2 1 3 3 2 1 1 Virulence Adhesion ss00413 0 0 0 0 0 1 0 0 0 0 Virulence Adhesion ss00711 8 8 3 4 4 6 2 4 2 1 Virulence Adhesion ss00712 6 2 0 2 5 5 7 15 1 3 Virulence Adhesion ss00752 256 233 191 216 254 437 238 414 225 184 Virulence Detection ss00328 31 24 20 17 15 31 15 24 19 17 Virulence Invasion and intracellular resistance ss00026 93 70 70 68 48 89 49 110 70 50 Virulence Invasion and intracellular resistance ss00183 1 1 0 0 0 0 1 1 0 0 Virulence Invasion and intracellular resistance ss00321 23 15 9 10 12 28 15 38 6 14 Virulence Invasion and intracellular resistance ss00342 2 7 1 1 1 2 2 4 0 3 Virulence Invasion and intracellular resistance ss00363 0 0 0 0 0 0 0 0 0 0 Virulence Invasion and intracellular resistance ss00979 1 1 0 0 0 0 1 1 0 0 Virulence Iron Scavenging Mechanisms ss00096 0 0 0 0 0 2 2 3 0 0 Virulence Iron Scavenging Mechanisms ss00122 40 40 20 38 82 120 53 119 57 30 Virulence Iron Scavenging Mechanisms ss00286 14 8 10 12 14 31 11 20 13 8 Virulence Iron Scavenging Mechanisms ss00426 162 167 157 164 191 436 330 526 227 168 Virulence Iron Scavenging Mechanisms ss00527 12 10 4 9 11 24 15 38 9 6 Virulence Iron Scavenging Mechanisms ss00620 201 172 69 90 157 272 180 299 104 92 Virulence Iron Scavenging Mechanisms ss00640 4 8 5 2 5 15 12 12 4 5 Virulence Iron Scavenging Mechanisms ss00720 75 54 25 45 53 89 52 105 36 31 Virulence Iron Scavenging Mechanisms ss00781 121 101 71 83 94 149 86 150 78 93 Virulence Iron Scavenging Mechanisms ss00890 0 1 0 0 1 1 1 2 0 0 Virulence Iron Scavenging Mechanisms ss01061 7 10 5 7 7 20 7 11 10 7 Virulence Pathogenicity islands ss00157 2 7 2 2 5 5 6 11 3 2 Virulence Pathogenicity islands ss00169 0 0 0 0 0 0 1 0 0 1 Virulence Pathogenicity islands ss00897 359 332 209 239 258 477 291 564 309 276 Virulence Quorum sensing and biofilm formation ss00109 0 0 0 0 0 0 0 0 0 0 Virulence Quorum sensing and biofilm formation ss00356 18 20 6 10 6 12 7 14 13 13 Virulence Quorum sensing and biofilm formation ss00360 3 1 2 2 5 5 3 6 3 2 Virulence Quorum sensing and biofilm formation ss00596 9 4 2 7 6 4 2 5 7 9 Virulence Regulation of virulence ss00008 1 0 1 1 0 0 2 2 2 0 Virulence Regulation of virulence ss00975 108 96 55 57 65 131 78 134 85 69 Virulence Regulation of virulence ss01053 1 0 1 1 0 2 1 0 2 1 Virulence Resistance to antibiotics and toxic compounds ss00035 0 0 0 0 0 0 0 0 0 0 Virulence Resistance to antibiotics and toxic compounds ss00042 129 103 46 59 25 54 30 67 83 86 Virulence Resistance to antibiotics and toxic compounds ss00045 328 314 138 173 266 488 285 538 243 215 Virulence Resistance to antibiotics and toxic compounds ss00124 1 1 1 0 1 1 0 1 0 0 Virulence Resistance to antibiotics and toxic compounds ss00185 4 2 0 1 2 6 3 6 1 2 Virulence Resistance to antibiotics and toxic compounds ss00207 7 8 4 6 4 10 6 12 4 3 Virulence Resistance to antibiotics and toxic compounds ss00209 4 5 1 4 0 6 3 7 1 3 Virulence Resistance to antibiotics and toxic compounds ss00267 0 0 0 0 0 2 0 0 0 0 Virulence Resistance to antibiotics and toxic compounds ss00277 782 655 552 629 247 442 232 431 691 631 Virulence Resistance to antibiotics and toxic compounds ss00407 7 6 1 1 2 5 2 4 3 2 Virulence Resistance to antibiotics and toxic compounds ss00465 12 7 11 14 38 74 36 51 18 12 Virulence Resistance to antibiotics and toxic compounds ss00473 614 558 733 860 298 581 356 593 836 702 Virulence Resistance to antibiotics and toxic compounds ss00509 20 13 7 10 6 7 4 7 11 11 Virulence Resistance to antibiotics and toxic compounds ss00541 115 81 17 22 40 52 34 76 33 18 Virulence Resistance to antibiotics and toxic compounds ss00552 0 0 0 0 0 0 1 4 0 1 Virulence Resistance to antibiotics and toxic compounds ss00558 0 0 0 0 0 0 0 0 0 0 Virulence Resistance to antibiotics and toxic compounds ss00585 444 396 235 316 298 597 317 642 395 331 Virulence Resistance to antibiotics and toxic compounds ss00733 11 13 14 19 7 12 3 9 17 14 Virulence Resistance to antibiotics and toxic compounds ss00736 11 8 6 8 4 8 7 17 11 11 Virulence Resistance to antibiotics and toxic compounds ss00742 1 2 0 1 1 1 0 2 0 2 Virulence Resistance to antibiotics and toxic compounds ss00799 260 224 116 161 168 291 190 346 197 145 Virulence Resistance to antibiotics and toxic compounds ss00800 5 5 6 7 0 4 2 0 4 6 Virulence Resistance to antibiotics and toxic compounds ss00873 47 47 19 22 5 11 5 12 22 11 Virulence Resistance to antibiotics and toxic compounds ss00882 3 4 2 3 5 11 3 11 6 1 Virulence Resistance to antibiotics and toxic compounds ss00951 46 31 39 41 47 64 48 81 52 32 Virulence Resistance to antibiotics and toxic compounds ss01058 85 73 48 56 76 139 62 135 68 53 Virulence Resistance to antibiotics and toxic compounds ss01060 157 120 138 194 154 268 193 343 213 166 Virulence Toxins and superantigens ss00422 3 4 0 1 0 4 3 4 2 3 Virulence Toxins and superantigens ss00495 0 0 0 0 0 1 1 2 0 1 Virulence Toxins and superantigens ss00646 0 1 0 0 1 0 0 1 0 0 Virulence Toxins and superantigens ss00914 0 0 0 0 0 0 0 0 0 0 Virulence Toxins and superantigens ss01011 0 0 0 0 0 0 0 0 0 0 Virulence Toxins and superantigens ss01015 0 0 0 0 0 0 0 0 0 0 Virulence Type III, Type IV, Type VI, ESAT secretion systems ss00085 212 154 95 109 58 99 54 111 89 77 Virulence Type III, Type IV, Type VI, ESAT secretion systems ss00117 11 8 6 9 14 24 14 24 4 5 Virulence Type III, Type IV, Type VI, ESAT secretion systems ss00306 37 35 15 16 8 26 10 15 15 14 Virulence Type III, Type IV, Type VI, ESAT secretion systems ss00693 22 20 11 16 15 22 15 36 20 16 Virulence Type III, Type IV, Type VI, ESAT secretion systems ss00716 0 0 0 0 0 0 1 0 0 0 Virulence Type III, Type IV, Type VI, ESAT secretion systems ss00900 11 8 7 6 8 5 5 9 5 3 Virulence Type III, Type IV, Type VI, ESAT secretion systems ss00937 563 483 249 295 206 398 249 467 356 300 Virulence Type III, Type IV, Type VI, ESAT secretion systems ss00990 4 3 3 1 2 1 1 3 1 2 Virulence Type III, Type IV, Type VI, ESAT secretion systems ss01079 68 51 32 42 57 89 46 79 50 33 Virulence Unclassified Subsystem ss00118 758 654 514 583 526 872 563 975 667 602 Virulence Unclassified Subsystem ss00129 6 4 4 3 3 4 3 8 5 4 Virulence Unclassified Subsystem ss00657 33 20 14 15 22 32 28 53 16 18 Virulence Unclassified Subsystem ss00683 17 11 16 16 5 9 3 6 12 8 Virulence Unclassified Subsystem ss00697 4 2 0 1 1 1 1 1 0 0 Virulence Unclassified Subsystem ss01006 146 117 75 80 120 203 108 218 97 81