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["Table S2 - Full information multiplexed immunoassay profiling."]
["Analysis of protein levels in serum of NR1neo-/- (n=12) and wildtype mice (n=12) using multiplexed immunoassay. The table includes Uniprot ID, gene names, ratios (calculated based on average), p-values (Mann Whitney U) and adjusted p-values (Benjamini-Hochberg corrected)"]
["Analyte Name","Uniprot Accession-Number","Uniprot-ID","Gene name","Ratio","p","p*"]
["Angiotensin-converting enzyme (ACE)","P09470","ACE_MOUSE","Ace Dcp1",{"v":1.10573092246399,"d":"1.11"},{"v":0.293014699142311,"d":"0.2930"},{"v":0.37954765868193,"d":"0.3795"}]
["Adrenocorticotropic hormone (ACTH)","P01193 ","COLI_MOUSE","Pomc Pomc2",{"v":0.584217673389328,"d":"0.58"},{"v":0.0105101636303258,"d":"0.0105"},{"v":0.0358301032852014,"d":"0.0358"}]
["Apolipoprotein A-I","Q00623 ","APOA1_MOUSE","Apoa1",{"v":16.7683784157253,"d":"16.77"},{"v":0.000736643891846476,"d":"0.0007"},{"v":0.00613869909872064,"d":"0.0061"}]
["Complement C3","P01027","CO3_MOUSE","C3",{"v":0.754105839416058,"d":"0.75"},{"v":0.171463107495938,"d":"0.1715"},{"v":0.257194661243908,"d":"0.2572"}]
["Calbindin","P12658","CALB1_MOUSE","Calb1",{"v":4.11988539708121,"d":"4.12"},{"v":0.055668016194332,"d":"0.0557"},{"v":0.109871084594076,"d":"0.1099"}]
["Tumor necrosis factor receptor superfamily member 5","P27512","TNR5_MOUSE","Cd40 Tnfrsf5",{"v":1.10337023884131,"d":"1.10"},{"v":0.44147656461959,"d":"0.4415"},{"v":0.517355349163582,"d":"0.5174"}]
["CD40 ligand","P27548","CD40L_MOUSE","Cd40lg Cd40l",{"v":0.946954813359528,"d":"0.95"},{"v":0.595970593745663,"d":"0.5960"},{"v":0.677239311074617,"d":"0.6772"}]
["Clusterin (Apolipoprotein J)","Q06890","CLUS_MOUSE","Clu Apoj Msgp-2",{"v":0.613394781833048,"d":"0.61"},{"v":0.00282924207652496,"d":"0.0028"},{"v":0.0151566539813837,"d":"0.0152"}]
["Cortisol","NA","NA","NA",{"v":0.913523573200993,"d":"0.91"},{"v":0.193639998129239,"d":"0.1936"},{"v":0.279288458840248,"d":"0.2793"}]
["C-reactive protein","P14847","CRP_MOUSE","Crp Ptx1",{"v":1.14058738565238,"d":"1.14"},{"v":0.285371559271553,"d":"0.2854"},{"v":0.37954765868193,"d":"0.3795"}]
["Cystatin-C","P21460","CYTC_MOUSE","Cst3",{"v":0.880235706322663,"d":"0.88"},{"v":0.053046277610996,"d":"0.0530"},{"v":0.107526238400668,"d":"0.1075"}]
["Epidermal growth factor","P01132","EGF_MOUSE","Egf",{"v":2.12005683984334,"d":"2.12"},{"v":0.028700378907891,"d":"0.0287"},{"v":0.0717509472697275,"d":"0.0718"}]
["Epidermal growth factor","P07522","EGF_RAT","Egf",{"v":2.42311196869808,"d":"2.42"},{"v":0.0235411960621609,"d":"0.0235"},{"v":0.0653922112837802,"d":"0.0654"}]
["Endothelin-1 (ET-1)","P22387","EDN1_MOUSE","Edn1",{"v":0.719640218676123,"d":"0.72"},{"v":0.0473417865527626,"d":"0.0473"},{"v":0.107526238400668,"d":"0.1075"}]
["Eotaxin (C-C motif chemokine 11)","P48298","CCL11_MOUSE","Ccl11 Scya11",{"v":0.501117491851622,"d":"0.50"},{"v":0.00241023465549675,"d":"0.0024"},{"v":0.0142861865220381,"d":"0.0143"}]
["Coagulation factor VII","P70375","FA7_MOUSE","F7 Cf7",{"v":0.855052264808362,"d":"0.86"},{"v":0.0308996465522108,"d":"0.0309"},{"v":0.0747572094005099,"d":"0.0748"}]
["Fibroblast growth factor 2 (FGF-2)","P15655","FGF2_MOUSE","Fgf2 Fgf-2",{"v":1.13271604938272,"d":"1.13"},{"v":0.0596920594766843,"d":"0.0597"},{"v":0.114792422070547,"d":"0.1148"}]
["Fibrinogen, alpha polypeptide (Protein Fga)","Q99K47","Q99K47_MOUSE","Fga",{"v":13.1940792607412,"d":"13.19"},{"v":0.000669849291379076,"d":"0.0007"},{"v":0.00613869909872064,"d":"0.0061"}]
["C-X-C motif chemokine 5 (Cytokine LIX)","P50228","CXCL5_MOUSE","Cxcl5 Scyb5",{"v":0.753888409134523,"d":"0.75"},{"v":0.00230354049021013,"d":"0.0023"},{"v":0.0142861865220381,"d":"0.0143"}]
["Glucagon-like peptide 1","P55095","GLUC_MOUSE","Gcg",{"v":1.00674443370014,"d":"1.01"},{"v":0.322835697023735,"d":"0.3228"},{"v":0.403544621279668,"d":"0.4035"}]
["Glucagon","P55095","GLUC_MOUSE","Gcg",{"v":1.41993041306093,"d":"1.42"},{"v":0.0201514897530719,"d":"0.0202"},{"v":0.0611969021965667,"d":"0.0612"}]
["Somatotropin (Growth hormone)","P06880","SOMA_MOUSE","Gh1 Gh",{"v":1.39279684862127,"d":"1.39"},{"v":0.393034314033156,"d":"0.3930"},{"v":0.467897992896615,"d":"0.4679"}]
["Glutathione S-transferase Mu 1","P10649","GSTM1_MOUSE","Gstm1",{"v":1.57241538868324,"d":"1.57"},{"v":0.00358962738361862,"d":"0.0036"},{"v":0.0158365913983175,"d":"0.0158"}]
["Haptoglobin","Q61646","HPT_MOUSE","Hp",{"v":1.59424741692265,"d":"1.59"},{"v":0.299986391317661,"d":"0.3000"},{"v":0.381338633030925,"d":"0.3813"}]
["Interferon gamma (IFN-gamma)","P01580","IFNG_MOUSE","Ifng",{"v":1.33241328773815,"d":"1.33"},{"v":0.285333944204702,"d":"0.2853"},{"v":0.37954765868193,"d":"0.3795"}]
["Immunoglobulin A (IGA)","NA","NA","IgA",{"v":0.74869459623558,"d":"0.75"},{"v":0.00345403401532234,"d":"0.0035"},{"v":0.0158365913983175,"d":"0.0158"}]
["Insulin-like growth factor I (IGF-I)","P05017 ","IGF1_MOUSE","Igf1 Igf-1",{"v":0.156102923854148,"d":"0.16"},{"v":0.000216325273089703,"d":"0.0002"},{"v":0.00598759122581811,"d":"0.0060"}]
["Interleukin-10 (IL-10)","P18893","IL10_MOUSE","Il10 Il-10",{"v":1.30404164115126,"d":"1.30"},{"v":0.104281615340631,"d":"0.1043"},{"v":0.17775275342153,"d":"0.1778"}]
["Interleukin-11 (IL-11)","P47873","IL11_MOUSE","Il11",{"v":1.52380952380952,"d":"1.52"},{"v":0.0212149260948098,"d":"0.0212"},{"v":0.0611969021965667,"d":"0.0612"}]
["Interleukin-12 subunit alpha (IL-12A)","P43431 ","IL12A_MOUSE","IL12A NKSF1",{"v":1.86046190015212,"d":"1.86"},{"v":0.000375529476090873,"d":"0.0004"},{"v":0.00598759122581811,"d":"0.0060"}]
["Interleukin-18 (IL-18)","P70380","IL18_MOUSE","Il18 Igif",{"v":0.858057059088859,"d":"0.86"},{"v":0.293516856047359,"d":"0.2935"},{"v":0.37954765868193,"d":"0.3795"}]
["Interleukin-1 alpha (IL-1 alpha)","P01582","IL1A_MOUSE","Il1a",{"v":1.33621876844383,"d":"1.34"},{"v":0.0792728187456415,"d":"0.0793"},{"v":0.148636535148078,"d":"0.1486"}]
["Interleukin-1 beta (IL-1 beta)","P10749 ","IL1B_MOUSE","IL1B IL1F2",{"v":0.583724137931035,"d":"0.58"},{"v":0.0102537728955253,"d":"0.0103"},{"v":0.0358301032852014,"d":"0.0358"}]
["Interleukin-2 (IL-2)","P04351","IL2_MOUSE","Il2 Il-2",{"v":1.96509556203434,"d":"1.97"},{"v":0.351320359238555,"d":"0.3513"},{"v":0.431951261358879,"d":"0.4320"}]
["Interleukin-4 (IL-4)","P07750","IL4_MOUSE","Il4 Il-4",{"v":1.00600695542207,"d":"1.01"},{"v":0.927577801173154,"d":"0.9276"},{"v":0.927577801173154,"d":"0.9276"}]
["Interleukin-7 (IL-7)","P10168","IL7_MOUSE","Il7 Il-7",{"v":1.40099508754251,"d":"1.40"},{"v":0.0518632748365679,"d":"0.0519"},{"v":0.107526238400668,"d":"0.1075"}]
["Insulin-1","P01325","INS1_MOUSE","Ins1 Ins-1",{"v":1.25719831769654,"d":"1.26"},{"v":0.0879461096179362,"d":"0.0879"},{"v":0.153394377240586,"d":"0.1534"}]
["C-X-C motif chemokine 10 (IP-10)","P17515","CXL10_MOUSE","Cxcl10 Crg2 Ifi10",{"v":1.22411655300682,"d":"1.22"},{"v":0.132989263190739,"d":"0.1330"},{"v":0.216830320419682,"d":"0.2168"}]
["Leptin (Obesity factor)","P41160","LEP_MOUSE","Lep Ob",{"v":0.485222222222222,"d":"0.49"},{"v":0.00509408159696146,"d":"0.0051"},{"v":0.0206055631139277,"d":"0.0206"}]
["Leukemia inhibitory factor (LIF)","P09056","LIF_MOUSE","Lif",{"v":0.926310955243821,"d":"0.93"},{"v":0.155675467147002,"d":"0.1557"},{"v":0.245503939974942,"d":"0.2455"}]
["Lymphotactin (C motif chemokine 1)","P47993","XCL1_MOUSE","Xcl1 Lptn Ltn",{"v":0.557385028533065,"d":"0.56"},{"v":0.0024762723304866,"d":"0.0025"},{"v":0.0142861865220381,"d":"0.0143"}]
["Macrophage colony-stimulating factor 1 (CSF-1)","P07141","CSF1_MOUSE","Csf1 Csfm",{"v":1.64654495484884,"d":"1.65"},{"v":0.00312744211501578,"d":"0.0031"},{"v":0.0156372105750789,"d":"0.0156"}]
["C-C motif chemokine 2 (MCP-1)","P10148","CCL2_MOUSE","Ccl2 Je Mcp1",{"v":1.07442089699359,"d":"1.07"},{"v":0.750674623217932,"d":"0.7507"},{"v":0.7712410512513,"d":"0.7712"}]
["C-C motif chemokine 7 (MCP-3)","Q03366","CCL7_MOUSE","Ccl7 Fic Mcp3",{"v":0.509970457902511,"d":"0.51"},{"v":0.00522007598886169,"d":"0.0052"},{"v":0.0206055631139277,"d":"0.0206"}]
["C-C motif chemokine 12 (MCP-5)","Q62401","CCL12_MOUSE","Ccl12 Mcp5",{"v":0.522268656716418,"d":"0.52"},{"v":0.000193616947595343,"d":"0.0002"},{"v":0.00598759122581811,"d":"0.0060"}]
["CC chemokine DC/B-CK (Chemokine (C-C motif) ligand 22)","Q546S6","Q546S6_MOUSE","Ccl22 DCBCK",{"v":0.824895118230359,"d":"0.82"},{"v":0.0209693531073923,"d":"0.0210"},{"v":0.0611969021965667,"d":"0.0612"}]
["C-C motif chemokine 3 (MIP-1-alpha)","P10855","CCL3_MOUSE","Ccl3 Mip1a Scya3",{"v":0.912232204561161,"d":"0.91"},{"v":0.0524633141698301,"d":"0.0525"},{"v":0.107526238400668,"d":"0.1075"}]
["C-C motif chemokine 4 (MIP-1-beta)","P14097","CCL4_MOUSE","Ccl4 Mip1b Scya4",{"v":1.02735457063712,"d":"1.03"},{"v":0.805162885346852,"d":"0.8052"},{"v":0.816043464878566,"d":"0.8160"}]
["C-X-C motif chemokine 2 (MIP2) _RAT","P10889 ","CXCL2_MOUSE","Cxcl2 Cinc3 Mip-2",{"v":0.772797074954296,"d":"0.77"},{"v":0.00144427940648824,"d":"0.0014"},{"v":0.0108320955486618,"d":"0.0108"}]
["C-X-C motif chemokine 2 (MIP2) _MOUSE","P10889","CXCL2_MOUSE","Cxcl2 Mip-2 Mip2",{"v":1.49192739671079,"d":"1.49"},{"v":0.052363970807821,"d":"0.0524"},{"v":0.107526238400668,"d":"0.1075"}]
["C-C motif chemokine 19","O70460","CCL19_MOUSE","Ccl19 Elc Scya19",{"v":0.883911368015414,"d":"0.88"},{"v":0.163811243120992,"d":"0.1638"},{"v":0.250731494572947,"d":"0.2507"}]
["Matrix metalloproteinase-9 (MMP-9)","P41245","MMP9_MOUSE","Mmp9 Clg4b",{"v":1.25610967613749,"d":"1.26"},{"v":0.0868725443562282,"d":"0.0869"},{"v":0.153394377240586,"d":"0.1534"}]
["Myeloperoxidase (MPO)","P11247","PERM_MOUSE","Mpo",{"v":1.5265863169089,"d":"1.53"},{"v":0.0246061484156692,"d":"0.0246"},{"v":0.0659093261133997,"d":"0.0659"}]
["Myoglobin","P04247","MYG_MOUSE","Mb",{"v":1.04048165137615,"d":"1.04"},{"v":0.645670620479924,"d":"0.6457"},{"v":0.701815891826004,"d":"0.7018"}]
["Neutrophil gelatinase-associated lipocalin (NGAL)","P11672","NGAL_MOUSE","Lcn2",{"v":3.26642119962565,"d":"3.27"},{"v":0.044304651303825,"d":"0.0443"},{"v":0.10383902649334,"d":"0.1038"}]
["Oncostatin-M (OSM)","P53347","ONCM_MOUSE","Osm",{"v":2.15056761601275,"d":"2.15"},{"v":0.0113517782481341,"d":"0.0114"},{"v":0.0370166682004373,"d":"0.0370"}]
["Osteopontin (2AR)","P10923","OSTP_MOUSE","Spp1 Eta-1 Op",{"v":0.358169001516909,"d":"0.36"},{"v":0.000288444897409765,"d":"0.0003"},{"v":0.00598759122581811,"d":"0.0060"}]
["Plasminogen activator inhibitor 1 (PAI)","P22777","PAI1_MOUSE","Serpine1 Mr1 Pai1",{"v":0.900786713286713,"d":"0.90"},{"v":0.125610320876891,"d":"0.1256"},{"v":0.209350534794818,"d":"0.2094"}]
["Progesterone","NA","NA","NA",{"v":0.695555201529393,"d":"0.70"},{"v":0.0831974817407182,"d":"0.0832"},{"v":0.152190515379363,"d":"0.1522"}]
["Prolactin (PRL)","P06879","PRL_MOUSE","Prl",{"v":0.969942891493838,"d":"0.97"},{"v":0.664181886274903,"d":"0.6642"},{"v":0.711623449580253,"d":"0.7116"}]
["Peptide YY (PYY)","Q9EPS2","PYY_MOUSE","Pyy",{"v":1.36656322730799,"d":"1.37"},{"v":0.200464506445582,"d":"0.2005"},{"v":0.283676188366389,"d":"0.2837"}]
["C-C motif chemokine 5 (T-cell-specific protein RANTES)","P30882","CCL5_MOUSE","Ccl5 Scya5",{"v":0.894972973800665,"d":"0.89"},{"v":0.64004248096874,"d":"0.6400"},{"v":0.701815891826004,"d":"0.7018"}]
["Serum amyloid P-component (SAP)","P12246","SAMP_MOUSE","Apcs Ptx2 Sap",{"v":1.02700646633701,"d":"1.03"},{"v":0.644209460464489,"d":"0.6442"},{"v":0.701815891826004,"d":"0.7018"}]
["Kit ligand (Stem cell factor)","P20826","SCF_MOUSE","Kitlg Kitl Mgf Sl Slf",{"v":0.767128874388255,"d":"0.77"},{"v":0.188081242955984,"d":"0.1881"},{"v":0.276590063170565,"d":"0.2766"}]
["Aspartate aminotransferase, cytoplasmic (cAspAT)","P05201","AATC_MOUSE","Got1",{"v":1.48372465314835,"d":"1.48"},{"v":0.157122521583963,"d":"0.1571"},{"v":0.245503939974942,"d":"0.2455"}]
["Testesteron","NA","NA","NA",{"v":0.915603939865215,"d":"0.92"},{"v":0.532631658697511,"d":"0.5326"},{"v":0.61457499080482,"d":"0.6146"}]
["Metalloproteinase inhibitor 1 (TIMP-1)","P12032 ","TIMP1_MOUSE","Timp1 Timp-1",{"v":2.72900542913249,"d":"2.73"},{"v":0.006660057987769,"d":"0.0067"},{"v":0.0249752174541338,"d":"0.0250"}]
["Metalloproteinase inhibitor 1 (TIMP-1)","P12032","TIMP1_MOUSE","Timp1 Timp",{"v":0.890386466785861,"d":"0.89"},{"v":0.263751553990307,"d":"0.2638"},{"v":0.366321602764315,"d":"0.3663"}]
["Tissue factor (TF)","P20352","TF_MOUSE","F3 Cf-3 Cf3",{"v":1.04127500602555,"d":"1.04"},{"v":0.731516010738269,"d":"0.7315"},{"v":0.765478250431066,"d":"0.7655"}]
["Tumor necrosis factor (TNF-alpha)","P06804","TNFA_MOUSE","Tnf Tnfa Tnfsf2",{"v":1.6639820191047,"d":"1.66"},{"v":0.0283453942759383,"d":"0.0283"},{"v":0.0717509472697275,"d":"0.0718"}]
["Thrombopoietin (C-mpl ligand)","P40226","TPO_MOUSE","Thpo",{"v":0.86248492159228,"d":"0.86"},{"v":0.386410377990797,"d":"0.3864"},{"v":0.467431908859835,"d":"0.4674"}]
["Vascular cell adhesion protein 1 (V-CAM 1)","P29533","VCAM1_MOUSE","Vcam1 Vcam-1",{"v":0.969656336909019,"d":"0.97"},{"v":0.734859120413823,"d":"0.7349"},{"v":0.765478250431066,"d":"0.7655"}]
["Vascular endothelial growth factor A (VEGF-A) _RAT","P16612","VEGFA_RAT","Vegfa Vegf",{"v":8.26082477680441,"d":"8.26"},{"v":0.000632042556774827,"d":"0.0006"},{"v":0.00613869909872064,"d":"0.0061"}]
["Vascular endothelial growth factor A (VEGF-A) _MOUSE","Q00731","VEGFA_MOUSE","Vegfa Vegf",{"v":7.40677719405454,"d":"7.41"},{"v":0.000399172748387874,"d":"0.0004"},{"v":0.00598759122581811,"d":"0.0060"}]
["von Willebrand factor (vWF)","Q8CIZ8","VWF_MOUSE","Vwf",{"v":2.98487330712101,"d":"2.98"},{"v":0.00054832498235866,"d":"0.0005"},{"v":0.00613869909872064,"d":"0.0061"}]