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["SUCCESS "]
["INFORMATION ABOUT YOUR RUN:"]
["Number of Genes:",6400]
["Number of Ensembles that Matched:",1282]
["Number of Samples:",57]
["Gene Expression File:","LungExpression.gex"]
["Signature File:","LungClasses.sig"]
["Customer Ensemble File:"]
["Identifier Type:","Gene Symbol"]
["Cat Size Range:","2-150 genes"]
["Siganture file interpretation: ","Categorical values (Classification)"]
["Execution Time:","2007-01-25T17:26:44"]
["RESULTS:"]
["Ensemble.Rank","Ensemble.Name","Ensemble Size","Median Ensemble p-value","FDR","FDR by GSEA","Gene.Importance Scores"]
[1,"electron transporter activity BioCarta",116,0,0,0,"(AKR1B10, 1.178)","(GPX2, 1.147)","(ALDH3A1, 1.073)","(AKR1C2, 1.06)","(CYP1B1, 1.039)","(AKR1C1, 1.025)","(AKR1C3, 0.907)","(ADH7, 0.729)","(AKR1B1, 0.664)","(MAOB, 0.636)","(DHRS3, 0.602)","(PGD, 0.544)","(TXN, 0.432)","(CYP4F11, 0.431)","(ERP70, 0.363)","(MB, 0.351)","(MTHFD2, 0.301)","(HPGD, 0.29)","(CYP39A1, 0.269)","(PHYH, 0.268)","(NQO2, 0.216)","(ME2, 0.209)","(ALDH2, 0.204)","(HSD17B8, 0.2)","(UQCR, 0.148)","(TXNL2, 0.142)","(PAM, 0.103)","(NCF1, 0.062)","(ALOX15B, 0.023)","(AKR1A1, 0.008)","(TSTA3, 0)","(SARDH, 0)","(MTRR, 0)","(GPX5, 0)","(CYP24A1, 0)","(COX5A, 0)","(RODH-4, 0)","(ALDH9A1, 0)","(CDO1, 0)","(PDHX, 0)","(GPX4, 0)","(PDIP, 0)","(AKR1D1, 0)","(P4HB, 0)","(ALDH5A1, 0)","(CYP26A1, 0)","(ALDH1A2, 0)","(ADH5, 0)","(DDO, 0)","(GPX3, 0)","(ME1, 0)","(QDPR, 0)","(PHGDH, 0)","(ALDH1A1, 0)","(IDH3B, 0)","(WWOX, 0)","(TXNDC5, 0)","(NNT, 0)","(DEGS, 0)","(PLOD, 0)","(SRD5A2, 0)","(COX11, 0)","(NCF2, 0)","(DAO, 0)","(RODH, 0)","(CYP11A1, 0)","(LOXL2, 0)","(QSCN6, 0)","(KMO, 0)","(NCF4, 0)","(CYP19A1, 0)","(DHCR7, 0)","(HMOX2, 0)","(FTHFD, 0)","(ME3, 0)","(ALOX12B, 0)","(COX15, 0)","(NOX4, 0)","(GRHPR, 0)","(ETFB, 0)","(UGDH, 0)","(EPX, 0)","(CYC1, 0)","(ADH6, 0)","(AOC3, 0)","(CYCS, 0)","(LOXL1, 0)","(GLDC, 0)","(AOC2, 0)","(SDHD, 0)","(INDO, 0)","(DHRS4, 0)","(BLVRA, 0)","(ADH1A, 0)","(SRD5A1, 0)","(SPR, 0)","(AKR7A2, 0)","(CYP1A2, 0)","(P4HA2, 0)","(PDIR, 0)","(ALDH4A1, 0)","(GRP58, 0)","(HNRPM, 0)","(HAAO, 0)","(GSR, 0)","(AKR1C4, 0)","(SDHA, 0)","(ADH1B, 0)","(PRDX2, 0)","(TXN2, 0)","(ASPH, 0)","(ADH1C, 0)","(H6PD, 0)","(DHRS2, 0)","(PPOX, 0)","(TXNDC3, 0)"]
[1,"carbohydrate metabolism (GO:0005975)",37,0,0,0,"(ALDH3A1, 1.626)","(TALDO1, 1.507)","(AKR1B1, 1.042)","(GALNT7, 0.88)","(GMDS, 0.803)","(TFF1, 0.712)","(SLC35A1, 0.499)","(CARKL, 0.498)","(SLC2A4, 0.437)","(ALDH2, 0.388)","(FUT3, 0.329)","(IDH1, 0.274)","(POMT1, 0.263)","(FUT4, 0.224)","(PIGQ, 0.126)","(PHKA2, 0.125)","(SLC2A2, 0.075)","(GUSB, 0.025)","(GALGT, 0.019)","(AKR7A2, 0)","(FUT2, 0)","(CNOT7, 0)","(FUT9, 0)","(B3GAT1, 0)","(SLC5A2, 0)","(IDH3B, -0.007)","(SLC2A5, -0.01)","(INSR, -0.014)","(ADRB3, -0.053)","(DHRS4, -0.053)","(DHRS2, -0.056)","(NAGPA, -0.057)","(FUT1, -0.062)","(MGAT1, -0.086)","(SPAM1, -0.096)","(FUT5, -0.133)","(SLC2A8, -0.193)"]
[1,"electron transport BioCarta",78,0,0,0.2354,"(CYP1B1, 1.293)","(CYP2A7, 0.882)","(MAOB, 0.816)","(CYP2A13, 0.653)","(CYP2A6, 0.649)","(TSAP6, 0.635)","(CYP1A1, 0.611)","(CYP4F11, 0.581)","(CYP4F3, 0.512)","(CYP2J2, 0.506)","(EIF2AK3, 0.464)","(CYP39A1, 0.423)","(CYP2F1, 0.366)","(SCO2, 0.327)","(CYP3A5, 0.301)","(HCCS, 0.285)","(FLJ20359, 0.278)","(CYP27A1, 0.26)","(CYP51A1, 0.243)","(SURF1, 0.239)","(CYP2E1, 0.223)","(CYP2B6, 0.213)","(CYP46A1, 0.209)","(CYBRD1, 0.209)","(CYP2D6, 0.186)","(PGRMC2, 0.165)","(FADS3, 0.145)","(FLJ23153, 0.14)","(CYP4F12, 0.136)","(FADS1, 0.121)","(CYB561, 0.11)","(CYP4A11, 0.096)","(CYP4B1, 0.089)","(DHODH, 0.013)","(CYP11A1, 0)","(CYP7A1, 0)","(PTGIS, 0)","(CYP2C18, 0)","(CYP19A1, 0)","(FADS2, 0)","(CYP27B1, 0)","(CYP7B1, 0)","(CYP24A1, 0)","(UQCRB, 0)","(SMOX, 0)","(FRDA, 0)","(UGDH, 0)","(CYB5, 0)","(PGRMC1, 0)","(MAOA, 0)","(CYP20A1, 0)","(CYP21A2, 0)","(CYP17A1, 0)","(CYB5-M, 0)","(CYP11B2, 0)","(CYP26A1, 0)","(PAOX, 0)","(UQCRH, 0)","(CYP3A4, 0)","(TBXAS1, 0)","(NUP62, 0)","(SUOX, 0)","(CYP1A2, 0)","(ERN1, 0)","(OXA1L, 0)","(SPUF, 0)","(CYP4F8, 0)","(NCB5OR, 0)","(CYP3A43, 0)","(FDXR, 0)","(CYP2C8, 0)","(ALAS2, 0)","(KIAA0090, 0)","(UQCRC1, 0)","(PPOX, 0)","(CYP3A7, 0)","(CYP2C9, 0)","(CYP4F2, 0)"]
[1,"MAP00480 Glutathione metabolism GenMAPP",19,0,0,0.30591,"(GPX2, 2.066)","(GCLM, 1.278)","(GSTM3, 0.999)","(GCLC, 0.791)","(GPX1, 0.753)","(GSTP1, 0.513)","(G6PD, 0.461)","(IDH1, 0.432)","(GSR, 0.161)","(GSTT2, 0.048)","(GSTM5, 0.042)","(GSTT1, 0.031)","(IDH2, 0.011)","(GPX4, -0.013)","(GSTM4, -0.014)","(GSTM1, -0.029)","(GPX3, -0.047)","(GGT1, -0.073)","(GSS, -0.076)"]
[1,"Pentose Phosphate Pathway BLACK",7,0,0,0.45894,"(TALDO1, 2.376)","(TKT, 2.224)","(PGD, 1.432)","(G6PD, 0.609)","(RPIA, 0.486)","(RPE, 0.242)","(PGLS, 0.118)"]
[6,"xenobiotic metabolism (GO:0006805)",12,0.002,0.016,0,"(AKR1C1, 2.165)","(NQO1, 2.018)","(UGT1A6, 1.549)","(CYP3A5, 0.613)","(UGT2B4, 0.443)","(NR1I2, 0.242)","(S100A12, 0.095)","(UGT2B15, 0.064)","(CYP3A4, -0.008)","(CYP3A7, -0.032)","(UGT2B28, -0.115)","(CYP3A43, -0.137)"]
[6,"MAP00512 O Glycans biosynthesis GenMAPP",8,0.002,0.016,0,"(GALNT6, 2.322)","(GALNT7, 1.593)","(SIAT4A, 1.351)","(GALNT1, 1.039)","(GCNT1, 0.074)","(GALNT3, 0.052)","(GALNT2, -0.199)","(GALNT8, -0.255)"]
[8,"pentosePathway BLACK",4,0.004,0.045,0.64724,"(PGD, 2.182)","(G6PD, 1.085)","(RPIA, 0.867)","(PGLS, 0.258)"]
[9,"protein amino acid O-linked glycosylation (GO:0006493)",11,0.006,0.069,0,"(GALNT6, 2.073)","(GALNT7, 1.459)","(GALNT1, 0.953)","(POMT1, 0.443)","(GYPC, 0.375)","(LDLR, 0.204)","(OGT, 0.172)","(GCNT2, 0.142)","(GCNT1, -0.013)","(OIP106, -0.158)","(GALNT2, -0.229)"]
[10,"MAP00030 Pentose phosphate pathway GenMAPP",16,0.007,0.094,0.24319,"(TALDO1, 1.981)","(ALDOA, 1.378)","(PGD, 1.247)","(GPI, 0.58)","(G6PD, 0.505)","(ALDOC, 0.274)","(PFKM, 0.191)","(FBP2, 0.123)","(PRPS2, 0.086)","(FBP1, 0.017)","(PFKL, 0.015)","(H6PD, -0.071)","(ALDOB, -0.106)","(PRPS1, -0.118)","(PFKP, -0.134)","(PGM1, -0.195)"]
[10,"MAP00361 gamma Hexachlorocyclohexane degradation GenMAPP",28,0.007,0.094,0.68132,"(CYP2A7, 1.307)","(CYP1A1, 1.058)","(CYP2A6, 1.016)","(CYP2J2, 0.809)","(CYP2F1, 0.594)","(CYP3A5, 0.507)","(CYP2E1, 0.448)","(CYP51A1, 0.389)","(CYP2D6, 0.345)","(CYP4B1, 0.256)","(CYP2B6, 0.223)","(ALPPL2, 0.206)","(ACP5, 0.132)","(CYP4F8, 0.027)","(ALPP, 0.027)","(CYP3A7, 0.001)","(CYP3A4, 0)","(ACP1, -0.025)","(ALPI, -0.03)","(ACPP, -0.055)","(CYP19A1, -0.08)","(CYP2C9, -0.095)","(ACP2, -0.102)","(CYP2C8, -0.102)","(PON1, -0.106)","(ALPL, -0.155)","(CYP1A2, -0.167)","(CYP2C18, -0.194)"]
[12,"MAP00350 Tyrosine metabolism GenMAPP",29,0.008,0.097,0.41429,"(ALDH3A1, 1.801)","(ADH7, 1.283)","(MAOB, 1.194)","(ALDH1A3, 0.546)","(DBH, 0.302)","(HGD, 0.294)","(TH, 0.226)","(PNMT, 0.213)","(DDC, 0.208)","(GOT2, 0.141)","(FAH, 0.135)","(ALDH3B1, 0.125)","(ARVCF, 0.103)","(ADH1C, 0.087)","(ADH5, 0.086)","(MAOA, 0.083)","(ADH1B, 0.055)","(COMT, 0.04)","(AOC3, 0.007)","(GOT1, 0)","(ADH6, 0)","(ADH1A, -0.005)","(ALDH3B2, -0.014)","(ABP1, -0.02)","(AOC2, -0.031)","(TYR, -0.057)","(HPD, -0.084)","(AOX1, -0.088)","(TAT, -0.157)"]
[13,"g1pPathway BLACK",3,0.01,0.105,0.89952,"(GALK1, 1.538)","(GALE, 0.977)","(GALT, 0.804)"]
[13,"T cell differentiation (GO:0030217)",2,0.01,0.105,0.92726,"(JAG2, 2.185)","(WWP1, 1.366)"]
[13,"fatty acid metabolism BioCarta",25,0.01,0.105,1,"(DHRS3, 1.245)","(PECI, 1.041)","(CYP2J2, 0.844)","(OKL38, 0.731)","(FAAH, 0.619)","(SC4MOL, 0.43)","(LPL, 0.367)","(ALOX15B, 0.344)","(GNPAT, 0.26)","(FABP1, 0.208)","(CYP4A11, 0.124)","(ALOX12, 0.123)","(CROT, 0.115)","(FABP7, 0.083)","(ACADSB, 0.033)","(ACOX3, 0.032)","(PPARA, 0.014)","(FABP2, 0.01)","(PCCA, -0.033)","(FASN, -0.047)","(ASAH1, -0.072)","(ABCD2, -0.085)","(LIPE, -0.095)","(PECR, -0.13)","(CD36, -0.171)"]
[16,"cysteine metabolism (GO:0006534)",2,0.011,0.105,0.85331,"(GCLM, 2.661)","(GCLC, 1.74)"]
[17,"retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)",10,0.013,0.11,0.47768,"(COPB2, 1.391)","(COPG, 1.152)","(COPE, 0.656)","(RER1, 0.426)","(COPB, 0.333)","(COPA, 0.302)","(COPZ1, 0.299)","(GBF1, 0.013)","(KIF1C, -0.058)","(ARCN1, -0.072)"]
[18,"aldehyde metabolism (GO:0006081)",7,0.014,0.11,0.70014,"(AKR1B10, 2.622)","(ALDH3A1, 2.378)","(ALDH7A1, 0.19)","(AKR1A1, 0.153)","(AKR7A2, 0.042)","(ALDH1A1, -0.076)","(ALDH9A1, -0.083)"]
[19,"digestion (GO:0007586)",35,0.016,0.114,0.29583,"(AKR1B10, 1.737)","(AKR1C2, 1.634)","(TFF3, 1.037)","(CAPN9, 0.844)","(CYP39A1, 0.55)","(AMY2B, 0.404)","(PYY, 0.212)","(NMU, 0.158)","(PPY, 0.15)","(MLNR, 0.142)","(ACSL1, 0.118)","(ELA3A, 0.091)","(SCTR, 0.075)","(HTR3A, 0.068)","(GALR1, 0.055)","(SSTR1, 0.034)","(PPARGC1A, 0.02)","(GALR2, 0.019)","(ATP8B1, 0)","(CCKBR, 0)","(MEP1B, 0)","(SSTR2, 0)","(PGC, 0)","(FABP2, 0)","(MEP1A, 0)","(CTRL, 0)","(CSN1S1, -0.008)","(PPYR1, -0.016)","(PRSS3, -0.022)","(TFF2, -0.034)","(SLC15A1, -0.076)","(VIPR1, -0.103)","(CTSE, -0.117)","(CCKAR, -0.118)","(AKR1D1, -0.16)"]
[19,"MAP00051 Fructose and mannose metabolism GenMAPP",23,0.016,0.114,0.96355,"(AKR1B1, 1.339)","(ALDOA, 1.317)","(PMM1, 0.957)","(GMPPA, 0.438)","(PMM2, 0.36)","(GMPPB, 0.238)","(ALDOC, 0.235)","(MPI, 0.229)","(PFKM, 0.158)","(SORD, 0.123)","(HK3, 0.116)","(FBP2, 0.064)","(HK1, 0.032)","(KHK, 0.02)","(FBP1, -0.012)","(PFKFB1, -0.014)","(TPI1, -0.029)","(GCK, -0.033)","(ALDOB, -0.036)","(PFKL, -0.045)","(FPGT, -0.048)","(PFKP, -0.064)","(HK2, -0.078)"]
[21,"MAP00380 Tryptophan metabolism GenMAPP",45,0.017,0.125,0.96271,"(CYP2A7, 1.079)","(MAOB, 1.036)","(CYP2A6, 0.854)","(CYP1A1, 0.847)","(CYP2J2, 0.655)","(CYP2F1, 0.473)","(CYP3A5, 0.44)","(ALDH2, 0.37)","(CYP2E1, 0.363)","(CYP51A1, 0.335)","(CYP2D6, 0.3)","(HADHA, 0.211)","(DDC, 0.209)","(CYP2B6, 0.201)","(ASMT, 0.174)","(AANAT, 0.117)","(CYP4B1, 0.072)","(MAOA, 0.043)","(ACAT1, 0.041)","(AOC3, 0.033)","(CYP4F8, 0.025)","(HAAO, 0.007)","(ALDH3A2, 0)","(GCDH, 0)","(CYP1A2, 0)","(WARS, 0)","(TDO2, 0)","(KYNU, 0)","(ECHS1, 0)","(ALDH1A1, 0)","(OGDH, 0)","(CYP2C8, 0)","(CYP3A7, 0)","(INDO, -0.005)","(AOC2, -0.015)","(ABP1, -0.031)","(CAT, -0.034)","(CYP3A4, -0.035)","(CYP2C18, -0.045)","(ALDH1B1, -0.065)","(WARS2, -0.087)","(AOX1, -0.1)","(CYP19A1, -0.103)","(CYP2C9, -0.117)","(EHHADH, -0.141)"]
[21,"steroid metabolism (GO:0008202)",9,0.017,0.125,1,"(AKR1B10, 2.548)","(SULT2B1, 1.115)","(CYP3A5, 0.744)","(NR1I2, 0.455)","(SULT1E1, 0.259)","(UGT2B15, -0.083)","(FDX1, -0.088)","(UGT2B17, -0.102)","(SULT2A1, -0.18)"]
[23,"freePathway Neutrophils release superoxide to induce lysis in invading bacteria; in neighboring endothelial cells, superoxide dismutase scavenges radicals but produces pro-apoptotic peroxides.",10,0.018,0.125,1,"(SOD1, 1.207)","(NFKB1, 1.127)","(GPX1, 1.054)","(XDH, 0.725)","(NOX1, 0.488)","(GSR, 0.381)","(IL8, -0.016)","(GSS, -0.044)","(TNF, -0.053)","(RELA, -0.253)"]
[24,"MAP00071 Fatty acid metabolism GenMAPP",45,0.021,0.128,0.55904,"(ADH7, 1.186)","(CYP2A7, 1.095)","(CYP1A1, 0.838)","(CYP2A6, 0.818)","(CYP2J2, 0.697)","(CYP2F1, 0.475)","(CYP3A5, 0.386)","(CYP2E1, 0.365)","(ALDH2, 0.356)","(CYP51A1, 0.313)","(CYP2D6, 0.269)","(HADHA, 0.198)","(CYP4B1, 0.193)","(CYP2B6, 0.177)","(CYP4F8, 0.133)","(ADH1C, 0.122)","(CPT2, 0.113)","(ADH5, 0.107)","(CDK3, 0.083)","(ADH1B, 0.059)","(ACADM, 0.044)","(CYP4A11, 0.01)","(ACADS, 0)","(ACADL, 0)","(ADH1A, 0)","(GCDH, 0)","(ACAT1, 0)","(CYP1A2, 0)","(ACAA2, 0)","(ECHS1, 0)","(ALDH1A1, 0)","(CYP3A4, -0.01)","(ALDH3A2, -0.014)","(CYP3A7, -0.019)","(CYP19A1, -0.019)","(ADH6, -0.034)","(HADHB, -0.055)","(CYP2C9, -0.075)","(ACAA1, -0.094)","(EHHADH, -0.096)","(CYP2C8, -0.102)","(CYP2C18, -0.113)","(ALDH1B1, -0.115)","(ACOX1, -0.117)","(CPT1A, -0.166)"]
[25,"lechtinPathway BioCarta",11,0.022,0.128,1,"(C3, 1.889)","(C6, 1.337)","(C2, 0.689)","(C4A, 0.485)","(MASP2, 0.206)","(C5, 0.142)","(C8A, 0.12)","(MBL2, -0.044)","(C7, -0.046)","(MASP1, -0.049)","(C9, -0.154)"]
[26,"classicPathway The classic complement pathway is initiated by antibodies and promotes phagocytosis and lysis of foreign cells as well as activating the inflammatory response.",12,0.023,0.133,1,"(C3, 1.887)","(C6, 1.317)","(C2, 0.606)","(C4A, 0.536)","(C5, 0.151)","(C8A, 0.113)","(C1R, 0.089)","(C1S, 0.086)","(C1QB, 0.061)","(C7, -0.028)","(C1QA, -0.054)","(C9, -0.152)"]
[27,"response to pathogenic bacteria (GO:0009618)",12,0.024,0.14,0.47619,"(C6, 1.273)","(NFKBIA, 1.226)","(NFKB1, 0.992)","(LBP, 0.348)","(IFNGR1, 0.275)","(C5, 0.178)","(IFNGR2, 0.123)","(C8A, 0.085)","(MARCO, 0.005)","(C8B, 0.001)","(C7, -0.045)","(CCL2, -0.072)"]
[28,"fatty acid metabolism (GO:0006631)",20,0.026,0.148,0.87104,"(DHRS3, 1.34)","(PECI, 1.192)","(FAAH, 0.627)","(SC4MOL, 0.537)","(ALOX15B, 0.43)","(LPL, 0.423)","(GNPAT, 0.313)","(FABP1, 0.188)","(CYP4A11, 0.185)","(CROT, 0.153)","(ACADSB, 0.093)","(ACOX3, 0.076)","(PPARA, 0.066)","(PCCA, 0.041)","(FABP7, 0.01)","(FABP2, -0.056)","(LIPE, -0.092)","(ABCD2, -0.094)","(ASAH1, -0.111)","(CD36, -0.195)"]
[29,"response to wounding (GO:0009611)",12,0.027,0.154,0.78353,"(CTGF, 1.285)","(ACHE, 0.75)","(F2RL3, 0.577)","(VWF, 0.409)","(HOXB13, 0.317)","(MDK, 0.304)","(FGF7, 0.249)","(ADM, 0.196)","(F2RL2, 0.159)","(F2, 0.062)","(F2R, -0.066)","(GAP43, -0.087)"]
[30,"mrpPathway BioCarta",6,0.028,0.158,0.89516,"(ABCC1, 2.359)","(GSTP1, 0.848)","(ABCB1, 0.59)","(ABCC3, 0.333)","(ABCB4, 0.003)","(ABCB11, -0.164)"]
[30,"embryonic limb morphogenesis (GO:0030326)",4,0.028,0.158,0.95456,"(JAG2, 1.925)","(SHFM1, 1.042)","(LMX1B, 0.347)","(MBNL1, -0.013)"]
[32,"Complement Activation Classical Processes involved in the classical complement cascade, which promotes microbial lysis, disposal of immune complexes, and regulation of other immune processes.",15,0.029,0.162,0.20435,"(C3, 1.753)","(C6, 1.207)","(C2, 0.608)","(C4A, 0.443)","(MGC2198, 0.175)","(C8A, 0.154)","(C1QB, 0.137)","(DAF, 0.123)","(C5, 0.109)","(C1S, 0.062)","(C7, -0.014)","(C1QA, -0.027)","(C8B, -0.054)","(C9, -0.075)","(MASP1, -0.087)"]
[33,"MAP00590 Prostaglandin and leukotriene metabolism GenMAPP",19,0.03,0.168,0,"(CBR3, 1.606)","(CBR1, 1.331)","(CYP4F3, 0.978)","(PLA2G4A, 0.626)","(PLA2G1B, 0.248)","(PLA2G5, 0.203)","(ALOX15, 0.175)","(ALOX12, 0.131)","(LTA4H, 0.021)","(PGDS, 0.005)","(ALOX5, 0.001)","(GGT1, -0.007)","(PLA2G2A, -0.018)","(TBXAS1, -0.039)","(CYP4F2, -0.042)","(PTGS2, -0.054)","(PTGIS, -0.081)","(PTGDS, -0.135)","(PTGS1, -0.136)"]
[33,"electron transport (GO:0006118)",11,0.03,0.168,0.99844,"(TXNL1, 1.166)","(POR, 1.081)","(HCCS, 0.957)","(SCO2, 0.811)","(SURF1, 0.675)","(UQCRH, 0.052)","(UQCRB, -0.085)","(OXA1L, -0.105)","(COVA1, -0.116)","(FDXR, -0.117)","(UQCRC1, -0.125)"]
[35,"alternativePathway The alternative complement pathway is an antibody-independent mechanism of immune activation that results in cell lysis via the membrane attack complex.",9,0.031,0.171,0,"(C3, 1.997)","(C6, 1.437)","(DF, 0.6)","(C5, 0.181)","(C8A, 0.152)","(BF, 0.118)","(C7, -0.037)","(PFC, -0.155)","(C9, -0.201)"]
[35,"MAP00360 Phenylalanine metabolism GenMAPP",16,0.031,0.171,0.50421,"(ALDH3A1, 2.153)","(MAOB, 1.393)","(ALDH1A3, 0.7)","(DDC, 0.259)","(ALDH3B1, 0.195)","(GOT2, 0.194)","(AOC3, 0.16)","(LPO, 0.081)","(MAOA, 0.079)","(MPO, 0.058)","(AOC2, -0.007)","(TAT, -0.046)","(ALDH3B2, -0.06)","(ABP1, -0.131)","(HPD, -0.161)","(GOT1, -0.184)"]
[35,"proton transport (GO:0015992)",12,0.031,0.171,0.79994,"(UCP2, 1.784)","(NOX1, 0.475)","(ATP6V0B, 0.407)","(UCP1, 0.342)","(ATP6AP1, 0.326)","(ATP6V0C, 0.265)","(ATP6V1F, 0.224)","(ATP6V1E1, 0.187)","(UCP3, 0.158)","(TCIRG1, 0.114)","(ATP6V0E, 0.023)","(ATP6V1C1, -0.038)"]
[35,"circadianPathway A heterodimer composed of Bmal1 and Clock acts as a transcription factor for proteins that regulate circadian rhythms, such as Per and Cry.",6,0.031,0.171,0.92909,"(PER1, 1.299)","(ARNTL, 0.834)","(CLOCK, 0.525)","(CSNK1E, 0.421)","(CRY2, 0.175)","(CRY1, 0.023)"]
[35,"tRNA transcription (GO:0009304)",2,0.031,0.171,0.93712,"(GTF3C1, 1.631)","(BRF1, 0.714)"]
[40,"energy derivation by oxidation of organic compounds (GO:0015980)",3,0.032,0.171,0.98605,"(ACADVL, 1.297)","(BCS1L, 1.084)","(CRAT, 0.422)"]
[41,"nitric oxide mediated signal transduction (GO:0007263)",5,0.033,0.171,0.88983,"(GUCY1A3, 1.199)","(DDAH2, 0.624)","(DDAH1, 0.467)","(GUCY1B3, 0.283)","(FPR1, 0.127)"]
[42,"intra-Golgi vesicle-mediated transport (GO:0006891)",12,0.035,0.18,0.55273,"(COPB2, 1.346)","(COPG, 1.121)","(COPE, 0.641)","(COPZ1, 0.343)","(NAPA, 0.339)","(COPB, 0.248)","(COG2, 0.184)","(COPA, 0.134)","(STX16, 0.055)","(ARCN1, 0.032)","(GOSR1, -0.037)","(NAPG, -0.052)"]
[43,"G2 phase of mitotic cell cycle (GO:0000085)",2,0.036,0.188,0.76876,"(KPNA2, 1.63)","(CHES1, 0.786)"]
[44,"lipid metabolism (GO:0006629)",62,0.037,0.194,0.46551,"(AKR1C2, 1.423)","(AKR1C3, 1.267)","(CHKA, 0.544)","(ALDH1A3, 0.437)","(PHYH, 0.405)","(AGPS, 0.384)","(MGLL, 0.311)","(CPNE3, 0.269)","(ZNF202, 0.244)","(SREBF1, 0.237)","(ALOX15B, 0.224)","(CPNE7, 0.209)","(PPARD, 0.183)","(ANXA1, 0.169)","(ACAT2, 0.146)","(LRP1, 0.145)","(UCP3, 0.139)","(LRP5, 0.136)","(FABP5, 0.135)","(ALDH3B1, 0.119)","(LDLR, 0.114)","(APOC1, 0.098)","(PAFAH1B1, 0.097)","(PMVK, 0.078)","(PPARG, 0.073)","(APOD, 0.06)","(PPARA, 0.039)","(PDE3A, 0.037)","(SREBF2, 0.033)","(APOBEC1, 0.028)","(CORIN, 0.028)","(BTNL3, 0.023)","(STARD3, 0.009)","(ABCB4, 0.007)","(ALOX12B, 0.003)","(CPNE1, 0)","(APOF, 0)","(ACOX1, 0)","(APOL2, 0)","(ATP8B1, 0)","(NR2F2, 0)","(CPNE6, 0)","(ACAD8, 0)","(AOAH, 0)","(ALDH3A2, 0)","(HNF4A, 0)","(ALDH3B2, 0)","(CDS1, 0)","(MGST3, 0)","(CYP3A4, 0)","(SC5DL, 0)","(PLTP, 0)","(HADH2, 0)","(TTPA, 0)","(APOL1, 0)","(PEMT, 0)","(MTP, 0)","(OCRL, -0.015)","(APOC4, -0.023)","(LIPT1, -0.037)","(LRP2, -0.064)","(RBP3, -0.078)"]
[45,"ANDROGEN UP GENES na",60,0.039,0.206,0.49726,"(AZGP1, 0.897)","(INPP4B, 0.784)","(HPGD, 0.471)","(KLK3, 0.441)","(PHYH, 0.428)","(ALDH1A3, 0.427)","(GUCY1A3, 0.418)","(VAPA, 0.417)","(SRP19, 0.397)","(SCD, 0.385)","(SMS, 0.328)","(ITGAV, 0.289)","(SAT, 0.257)","(KLK2, 0.252)","(HMGCS1, 0.209)","(AKAP12, 0.207)","(GSR, 0.169)","(ABCC4, 0.161)","(DNAJB9, 0.111)","(ANKH, 0.107)","(ELL2, 0.106)","(PPAP2A, 0.099)","(SORD, 0.093)","(MERTK, 0.062)","(TMPRSS2, 0.059)","(MAF, 0.046)","(LIFR, 0.042)","(FKBP5, 0.015)","(IDI1, 0.009)","(SEPP1, 0.009)","(SGK, 0.007)","(KRT19, 0)","(SNAP25, 0)","(UGDH, 0)","(B4GALT1, 0)","(ID2, 0)","(RBM10, 0)","(DHCR24, 0)","(LIM, 0)","(ORM2, 0)","(APPBP2, 0)","(DCTN3, 0)","(SEC24D, 0)","(NDRG1, 0)","(LMAN1, 0)","(H1F0, 0)","(CAMKK2, 0)","(KLF4, 0)","(TMEPAI, 0)","(DBI, 0)","(PTPN21, 0)","(ADRM1, -0.01)","(HERC3, -0.02)","(IQGAP2, -0.024)","(CPD, -0.031)","(UAP1, -0.032)","(SLC26A2, -0.036)","(B2M, -0.041)","(ACTN1, -0.05)","(TPD52, -0.11)"]
[45,"regulation of cell proliferation (GO:0042127)",7,0.039,0.206,0.83821,"(JAG2, 1.549)","(RBM9, 0.866)","(BMP10, 0.37)","(CHRNA10, 0.263)","(BRCA1, 0.114)","(SCAND1, 0.081)","(TCFL5, 0.016)"]
[47,"sensory perception of smell (GO:0007608)",4,0.04,0.214,0,"(SLIT2, 2.67)","(OMP, 0.78)","(OR1D2, 0.005)","(OR52A1, -0.028)"]
[48,"alcohol metabolism (GO:0006066)",4,0.042,0.221,0.93719,"(ALDH1A3, 1.426)","(ALDH2, 1.108)","(ALDH3B1, 0.278)","(ALDH3B2, 0.042)"]
[49,"cytokinesis (GO:0000910)",2,0.044,0.229,0.92868,"(DIAPH2, 2.49)","(AURKC, 0.58)"]
[50,"DNA replication-dependent nucleosome assembly (GO:0006335)",2,0.045,0.238,0.86949,"(CHAF1B, 2.122)","(CHAF1A, 0.687)"]
[51,"etsPathway The Ets transcription factors are activated by Ras and promote macrophage differentiation.",16,0.047,0.247,0.68068,"(NCOR2, 1.352)","(SIN3B, 0.658)","(HDAC5, 0.61)","(JUN, 0.445)","(RBL1, 0.302)","(E2F1, 0.282)","(CSF1, 0.255)","(RBL2, 0.234)","(ETV3, 0.168)","(FOS, 0.164)","(ETS2, 0.095)","(HDAC2, 0.059)","(E2F4, 0.022)","(HRAS, -0.06)","(ETS1, -0.133)","(CSF1R, -0.188)"]
[51,"FRASOR ER DOWN Frasor et al 2004",68,0.047,0.247,1,"(SLIT2, 1.088)","(ANXA3, 0.702)","(GNE, 0.667)","(MB, 0.467)","(INHBB, 0.415)","(CTSL, 0.402)","(KRTHB1, 0.391)","(IRF6, 0.291)","(MATN2, 0.288)","(ARHE, 0.278)","(BCAS1, 0.231)","(PIB5PA, 0.23)","(LHFPL2, 0.2)","(LITAF, 0.198)","(EPOR, 0.186)","(NFRKB, 0.173)","(IER3, 0.168)","(MMD, 0.152)","(RAP1GA1, 0.131)","(CLU, 0.102)","(ERBB2, 0.095)","(D2S448, 0.085)","(STXBP1, 0.08)","(ASPH, 0.065)","(PVALB, 0.061)","(NELL2, 0.038)","(LAMB2, 0.032)","(CBX6, 0.027)","(MXD4, 0.016)","(CTSH, 0.01)","(BIK, 0.01)","(HIST2H2BE, 0.006)","(KIAA0922, 0.002)","(STC1, 0)","(TGFB2, 0)","(L1CAM, 0)","(IFI30, 0)","(ARNT2, 0)","(LAMB1, 0)","(CD24, 0)","(EFNA1, 0)","(MYO1B, 0)","(HIST2H2AA, 0)","(KYNU, 0)","(TM4SF1, 0)","(SELENBP1, 0)","(TGFB3, 0)","(ABCC5, 0)","(GNS, 0)","(BMP4, 0)","(ENC1, 0)","(DBN1, 0)","(ECH1, 0)","(RAI3, 0)","(FMO5, 0)","(FOLH1, 0)","(DUSP1, 0)","(KRT7, 0)","(NDRG1, 0)","(ALDH4A1, 0)","(DUSP4, 0)","(PPP1R3C, 0)","(PRPS1, 0)","(IL1R1, 0)","(ABCG1, 0)","(COPEB, -0.065)","(BLNK, -0.104)","(ASB9, -0.112)"]
[53,"response to external stimulus (GO:0009605)",4,0.049,0.258,0.96229,"(INHBB, 1.368)","(INHA, 0.941)","(RPS6KA5, 0.525)","(INHBA, -0.105)"]
[53,"egfr smrtePathway EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers.",11,0.049,0.258,1,"(NCOR2, 1.48)","(ZNF145, 1.399)","(RXRA, 0.65)","(EGF, 0.349)","(MAPK14, 0.197)","(THRB, 0.091)","(EGFR, 0.055)","(RARA, 0.032)","(MAP2K1, -0.072)","(THRA, -0.106)","(MAP3K1, -0.158)"]
[55,"compPathway Both the classic and alternative immune complement pathways promote inflammation, foreign cell lysis, and phagocytosis.",17,0.05,0.263,0.19336,"(C3, 1.668)","(C6, 1.159)","(C2, 0.536)","(DF, 0.53)","(C4A, 0.458)","(MASP2, 0.165)","(C8A, 0.141)","(C1QB, 0.1)","(C5, 0.079)","(BF, 0.066)","(C1R, 0.033)","(C7, 0.003)","(C1S, 0)","(C1QA, -0.037)","(MASP1, -0.045)","(MBL2, -0.084)","(C9, -0.135)"]
[55,"lairPathway BioCarta",16,0.05,0.263,0.25921,"(C3, 1.741)","(C6, 1.208)","(IL1A, 0.569)","(SELP, 0.256)","(ITGB2, 0.211)","(ITGAL, 0.17)","(ITGA4, 0.156)","(IL6, 0.128)","(C5, 0.126)","(ITGB1, 0.028)","(C7, -0.044)","(TNF, -0.058)","(SELPLG, -0.058)","(IL8, -0.078)","(ICAM1, -0.098)","(VCAM1, -0.17)"]
[57,"glial cell migration (GO:0008347)",2,0.053,0.277,0.81373,"(SLIT2, 3.035)","(AZU1, 0.358)"]
[58,"flumazenilPathway Flumazenil is a benzodiazepine receptor antagonist that may induce protective preconditioning in ischemic cardiomyocytes.",9,0.054,0.278,0.99027,"(SOD1, 1.312)","(GPX1, 1.195)","(GABRA1, 0.309)","(PRKCE, 0.308)","(GABRA3, 0.246)","(GABRA4, 0.023)","(GABRA6, -0.018)","(GABRA2, -0.021)","(GABRA5, -0.168)"]
[59,"actinYPathway The Arp 2/3 complex localizes to the Y-junction of polymerizing actin fibers that enable lamellipod extension and consequent cell motility.",18,0.055,0.282,0.41193,"(PIR, 2.028)","(ARPC1B, 0.684)","(ARPC3, 0.48)","(ARPC4, 0.421)","(RAC1, 0.273)","(ACTA1, 0.24)","(ARPC1A, 0.222)","(PSMA7, 0.216)","(WASF1, 0.108)","(NCK1, 0.097)","(ACTR3, 0.09)","(NTRK1, 0.038)","(WASL, -0.032)","(WASF2, -0.041)","(ARPC2, -0.057)","(WASF3, -0.058)","(NCKAP1, -0.072)","(ACTR2, -0.176)"]
[59,"MAP00340 Histidine metabolism GenMAPP",20,0.055,0.282,0.54707,"(ALDH3A1, 2.002)","(MAOB, 1.302)","(ALDH1A3, 0.702)","(ALDH2, 0.503)","(DDC, 0.259)","(AOC3, 0.193)","(ALDH3B1, 0.121)","(MAOA, 0.096)","(HNMT, 0.066)","(ASPA, 0.019)","(AOC2, -0.016)","(ALDH1B1, -0.034)","(HDC, -0.041)","(ABP1, -0.064)","(ALDH1A1, -0.087)","(ALDH3A2, -0.088)","(ALDH3B2, -0.102)","(HARS, -0.105)","(HAL, -0.144)","(HARSL, -0.163)"]
[61,"male genitalia morphogenesis (GO:0030539)",2,0.057,0.287,0.91424,"(LHCGR, 1.031)","(HSD17B3, 1.014)"]
[62,"circulation (GO:0008015)",32,0.059,0.296,0.71307,"(SERPING1, 1.161)","(GCLC, 0.799)","(GUCY1A3, 0.588)","(APOC2, 0.425)","(MEOX2, 0.361)","(LPL, 0.34)","(ADORA2A, 0.289)","(LPA, 0.249)","(TBC1D8, 0.238)","(ELN, 0.231)","(HTR2B, 0.196)","(EPB41, 0.164)","(CXCL12, 0.157)","(APOA1, 0.098)","(ADM, 0.093)","(GUCY1B3, 0.085)","(NFE2, 0.046)","(COL3A1, 0.034)","(ENG, 0.03)","(HOXB2, 0.028)","(HTR7, 0.019)","(AVPR1A, 0.011)","(CLNS1A, 0.009)","(ACVRL1, 0.001)","(COL4A3, 0)","(PPYR1, 0)","(FER1L3, -0.007)","(CXCL10, -0.05)","(DSCR1, -0.098)","(MTHFR, -0.109)","(C3AR1, -0.138)","(APOA4, -0.143)"]
[62,"superoxide metabolism (GO:0006801)",6,0.059,0.296,0.92978,"(CCS, 1.165)","(NOS2A, 0.854)","(NCF1, 0.703)","(NCF2, 0.29)","(CYBA, 0.147)","(SOD2, -0.059)"]
[64,"MAP00010 Glycolysis Gluconeogenesis GenMAPP",51,0.06,0.301,0.38564,"(ALDH3A1, 1.528)","(ADH7, 1.072)","(ALDOA, 1.008)","(ALDH1A3, 0.417)","(GPI, 0.394)","(ALDH2, 0.349)","(ENO1, 0.267)","(PDHB, 0.198)","(PKLR, 0.166)","(PGAM1, 0.159)","(ALDOC, 0.15)","(ALDH3B1, 0.139)","(ADH5, 0.098)","(PGAM2, 0.098)","(ACYP1, 0.093)","(FBP2, 0.085)","(ADH1C, 0.082)","(PFKM, 0.067)","(TPI1, 0.014)","(GAPD, 0.008)","(FBP1, 0.007)","(HK3, 0.001)","(PGK1, 0)","(PDHA1, 0)","(ENO2, 0)","(HK2, 0)","(DLD, 0)","(LDHA, 0)","(PDHA2, 0)","(PFKP, 0)","(ADH6, 0)","(ALDH3B2, 0)","(ADH1A, 0)","(ALDOB, 0)","(ENO3, 0)","(GCK, 0)","(PKM2, 0)","(ADH1B, 0)","(BPGM, -0.006)","(ALDH3A2, -0.014)","(HK1, -0.014)","(ACYP2, -0.019)","(ALDH1A1, -0.028)","(LDHB, -0.034)","(ALDH1B1, -0.049)","(DLAT, -0.076)","(PFKL, -0.085)","(G6PC, -0.095)","(LDHC, -0.103)","(BID, -0.11)","(PGM1, -0.204)"]
[64,"cell motility Any process involved in the controlled movement of a cell.",112,0.06,0.301,0.81124,"(CHST4, 0.579)","(TXN, 0.534)","(CTGF, 0.487)","(KAL1, 0.466)","(TSPAN-1, 0.443)","(LTB4R, 0.338)","(TPBG, 0.332)","(SPINT2, 0.311)","(ARPC1B, 0.307)","(PALM, 0.304)","(CRK, 0.272)","(SERPINB5, 0.246)","(UBE3A, 0.236)","(ADRA2A, 0.234)","(TM4SF8, 0.229)","(ARPC4, 0.227)","(THBS4, 0.226)","(SERPINI2, 0.218)","(CSPG4, 0.209)","(ARPC3, 0.202)","(ARFIP2, 0.202)","(THBS3, 0.2)","(MKLN1, 0.194)","(VNN1, 0.168)","(CAPZA1, 0.149)","(FLNA, 0.138)","(NEO1, 0.127)","(ANXA1, 0.118)","(PAFAH1B1, 0.113)","(PYY, 0.107)","(TM4SF9, 0.053)","(CCL3, 0.05)","(ITGAL, 0.034)","(CCL4, 0.024)","(FPR1, 0.021)","(VASP, 0.015)","(MAPK14, 0.015)","(VNN2, 0.007)","(SPOCK, 0.007)","(IL13, 0)","(JAK2, 0)","(CORO1A, 0)","(KPTN, 0)","(NTF3, 0)","(MST1R, 0)","(PTGS2, 0)","(FPRL1, 0)","(ARPC5, 0)","(IFNG, 0)","(HRAS, 0)","(GNA13, 0)","(PAFAH1B2, 0)","(LSP1, 0)","(WASL, 0)","(PAK4, 0)","(IL8RB, 0)","(F2R, 0)","(RAC1, 0)","(FPRL2, 0)","(LIMK1, 0)","(TNFRSF12A, 0)","(CXCR3, 0)","(CXCL10, 0)","(MAP2K1, 0)","(ACTR3, 0)","(MARCKS, 0)","(IL8, 0)","(CRKL, 0)","(PECAM1, 0)","(AAMP, 0)","(MSN, 0)","(CD97, 0)","(HMMR, 0)","(HGF, 0)","(FN1, 0)","(DNALI1, 0)","(OR1D2, 0)","(ACTR2, 0)","(SEMA3E, 0)","(FLJ10211, 0)","(ACTN4, 0)","(NTN1, 0)","(AKAP3, 0)","(WASF1, 0)","(MMP12, 0)","(IGF1, 0)","(AMFR, 0)","(BLR1, 0)","(MAPK8, 0)","(C3AR1, 0)","(AKAP4, 0)","(KATNB1, 0)","(NPY, 0)","(NOS3, 0)","(CAPZA2, 0)","(HGFAC, 0)","(TM4SF6, 0)","(STAT3, 0)","(SELL, 0)","(ENPP2, 0)","(F11R, 0)","(YARS, 0)","(TSPAN-2, 0)","(CCL5, 0)","(ARPC2, 0)","(THBS1, 0)","(XLKD1, 0)","(CSPG3, 0)","(MIR, 0)","(HUMAUANTIG, 0)","(DNAH9, 0)","(ACTB, 0)"]
[66,"L-phenylalanine catabolism (GO:0006559)",2,0.061,0.305,0.69787,"(HGD, 1.198)","(GSTZ1, 0.882)"]
[67,"positive regulation of follicle-stimulating hormone secretion (GO:0046881)",3,0.062,0.308,0.72902,"(INHBB, 1.547)","(INHA, 1.053)","(INHBA, -0.128)"]
[67,"HTERT DOWN Smith et al 2003",66,0.062,0.308,1,"(AKR1C3, 1.272)","(CBR1, 0.873)","(SERPING1, 0.836)","(RAB11A, 0.59)","(ACLY, 0.521)","(PIK3R3, 0.482)","(TRADD, 0.433)","(ATP5O, 0.311)","(PTPNS1, 0.223)","(DNA2L, 0.215)","(POU5F1, 0.199)","(UNC119, 0.191)","(SRD5A1, 0.187)","(PAM, 0.175)","(TAGLN, 0.142)","(PCNA, 0.133)","(TST, 0.129)","(SAA1, 0.121)","(ANXA4, 0.117)","(HEAB, 0.103)","(KIAA0140, 0.101)","(CALML3, 0.086)","(SORD, 0.085)","(PML, 0.082)","(UGP2, 0.065)","(FAH, 0.056)","(RAB40B, 0.043)","(TCF4, 0.017)","(ALDH7A1, 0.016)","(NID2, 0.005)","(PPP1R7, 0.004)","(NME4, 0)","(IDI1, 0)","(GM2A, 0)","(PCOLN3, 0)","(KYNU, 0)","(A2M, 0)","(ASAH1, 0)","(IL1RN, 0)","(DUSP6, 0)","(GSTO1, 0)","(DHCR24, 0)","(FOSB, 0)","(GSN, 0)","(AKT1, 0)","(TNFSF9, 0)","(VSNL1, 0)","(AHCY, 0)","(RRAGA, 0)","(CD47, 0)","(XRCC5, 0)","(TUBB4, 0)","(APEG1, 0)","(PGF, 0)","(ANKRD15, -0.005)","(PON2, -0.007)","(ABR, -0.007)","(STAT4, -0.008)","(GAMT, -0.008)","(CCNG1, -0.009)","(VAV2, -0.022)","(ALDH3A2, -0.049)","(RIG, -0.092)","(EHHADH, -0.118)","(TNFSF10, -0.135)","(ARHGDIB, -0.203)"]
[69,"'de novo' GDP-L-fucose biosynthesis (GO:0042351)",2,0.066,0.324,0.84823,"(GMDS, 2.425)","(TSTA3, 0.229)"]
[70,"proteasomePathway BioCarta",21,0.067,0.328,0.55777,"(RPN1, 0.672)","(PSMD14, 0.611)","(PSMB5, 0.454)","(UBE3A, 0.377)","(PSMB6, 0.351)","(RPN2, 0.323)","(PSMB3, 0.267)","(PSMB1, 0.223)","(PSMB4, 0.22)","(PSMB2, 0.202)","(PSMA5, 0.155)","(PSMA7, 0.154)","(PSMA6, 0.072)","(PSMA3, 0.049)","(PSMA2, 0.044)","(UBE2A, -0.03)","(UBE1, -0.062)","(PSMB7, -0.069)","(PSMA4, -0.1)","(PSMC3, -0.126)","(PSMA1, -0.136)"]
[71,"breast cancer estrogen signalling GEArray",101,0.068,0.335,0.54516,"(C3, 0.959)","(TFF3, 0.774)","(AZGP1, 0.725)","(ITGA6, 0.686)","(TFF1, 0.532)","(SCGB2A1, 0.429)","(BAG1, 0.42)","(CLDN7, 0.388)","(MT3, 0.351)","(GNAS, 0.254)","(MKI67, 0.218)","(THBS2, 0.212)","(IL6R, 0.203)","(RAC2, 0.2)","(ATF2, 0.196)","(BPAG1, 0.194)","(SERPINB5, 0.19)","(TIE, 0.189)","(JUN, 0.188)","(CCNE1, 0.145)","(SERPINE1, 0.137)","(CTSD, 0.137)","(KRT18, 0.116)","(STC2, 0.078)","(THBS4, 0.074)","(CDKN1B, 0.03)","(PGR, 0.009)","(PAPPA, 0.007)","(CCNA1, 0.006)","(SPRR1B, 0)","(NME1, 0)","(F3, 0)","(TOP2A, 0)","(CTNNB1, 0)","(MAP2K7, 0)","(PTGS2, 0)","(FHL5, 0)","(MLP, 0)","(PLAU, 0)","(TP53, 0)","(ID2, 0)","(CCNE2, 0)","(IGFBP2, 0)","(GATA3, 0)","(CD44, 0)","(GSN, 0)","(ITGB4, 0)","(ERBB2, 0)","(CCND1, 0)","(PPIA, 0)","(SLC7A5, 0)","(SCGB1D2, 0)","(CCNA2, 0)","(TGFA, 0)","(GABRP, 0)","(NFYB, 0)","(IL6, 0)","(TNFSF6, 0)","(KLK5, 0)","(FOSL1, 0)","(DLC1, 0)","(KRT19, 0)","(CTSB, 0)","(IL6ST, 0)","(RPL27, 0)","(FGF1, 0)","(FLRT1, 0)","(CYP19A1, 0)","(NGFR, 0)","(PPP1R15A, 0)","(CLU, 0)","(IL2RA, 0)","(SCGB2A2, 0)","(BCL2, 0)","(HSPB1, 0)","(HMGB1, 0)","(MUC1, 0)","(TNFAIP2, 0)","(CDKN2A, 0)","(TNFRSF6, 0)","(ESR1, 0)","(EGFR, 0)","(ESR2, 0)","(RPL13A, 0)","(S100A2, 0)","(KLF5, 0)","(SERPINA3, 0)","(NGFB, 0)","(KRTHB6, 0)","(AR, 0)","(GAPD, 0)","(THBS1, 0)","(CDH1, 0)","(BAD, 0)","(BCL2L2, 0)","(COL6A1, 0)","(CDKN1A, 0)","(ACTB, 0)","(PTEN, 0)","(VEGF, -0.006)","(KIT, -0.033)"]
[72,"MAP03070 Type III secretion system GenMAPP",18,0.069,0.335,0.52667,"(ATP6V0A4, 0.912)","(ATP6V1D, 0.713)","(ATP6V1B1, 0.668)","(ATP6V0B, 0.414)","(ATP5E, 0.365)","(ATP6V1F, 0.309)","(ATP6AP1, 0.235)","(ATP6V1E1, 0.166)","(ATP6V0C, 0.156)","(ATP6V1G1, 0.09)","(ATP6V1A, 0.086)","(ATP6V1G2, 0.08)","(ATP6V0D1, -0.054)","(ATP6V0E, -0.094)","(ATP6V0A1, -0.095)","(ATP6V1B2, -0.105)","(MPP5, -0.116)","(ATP6V1C1, -0.183)"]
[73,"MAP00193 ATP synthesis GenMAPP",18,0.07,0.338,0.52667,"(ATP6V0A4, 0.895)","(ATP6V1D, 0.696)","(ATP6V1B1, 0.662)","(ATP6V0B, 0.354)","(ATP5E, 0.315)","(ATP6V1F, 0.301)","(ATP6AP1, 0.226)","(ATP6V1E1, 0.179)","(ATP6V0C, 0.155)","(ATP6V1A, 0.116)","(ATP6V1G2, 0.106)","(ATP6V1G1, 0.032)","(ATP6V0D1, 0.014)","(ATP6V1B2, -0.034)","(ATP6V0E, -0.036)","(MPP5, -0.111)","(ATP6V1C1, -0.145)","(ATP6V0A1, -0.162)"]
[73,"nitric oxide biosynthesis (GO:0006809)",6,0.07,0.338,0.87712,"(NQO1, 2.692)","(DDAH2, 0.565)","(GCHFR, 0.115)","(ARG2, 0.068)","(GCH1, -0.059)","(AKT1, -0.177)"]
[73,"rRNA transcription (GO:0009303)",3,0.07,0.338,0.90179,"(GTF3C1, 1.402)","(BRF1, 0.684)","(GTF3A, 0.026)"]
[73,"fructose metabolism (GO:0006000)",5,0.07,0.338,0.97175,"(ALDOA, 2.207)","(ALDOC, 0.54)","(FBP2, 0.382)","(FBP1, 0.038)","(ALDOB, -0.033)"]
[77,"MAP00251 Glutamate metabolism GenMAPP",20,0.073,0.35,0.3512,"(GCLM, 1.398)","(GCLC, 0.924)","(GFPT1, 0.812)","(GAD1, 0.566)","(GPT, 0.217)","(GSR, 0.217)","(GOT2, 0.187)","(ABAT, 0.186)","(CAD, 0.151)","(GLUL, 0.028)","(EPRS, 0.012)","(QARS, -0.009)","(GMPS, -0.025)","(GLUD1, -0.057)","(GOT1, -0.083)","(ALDH5A1, -0.087)","(PPAT, -0.088)","(GSS, -0.091)","(GAD2, -0.135)","(CPS1, -0.163)"]
[77,"RAR UP Manually Curated",35,0.073,0.35,0.5224,"(C3, 1.347)","(DHRS3, 1.082)","(LAMP2, 0.602)","(MSLN, 0.533)","(FDFT1, 0.369)","(ANXA6, 0.28)","(CASP3, 0.271)","(SSR1, 0.19)","(RB1, 0.183)","(LBP, 0.177)","(DGAT1, 0.118)","(SNX10, 0.101)","(SLC12A2, 0.094)","(MXD4, 0.074)","(NET1, 0.015)","(CP, 0.011)","(CASP1, 0)","(VEGFC, 0)","(ENPP2, -0.003)","(ABCA1, -0.007)","(SIAT4C, -0.007)","(CTSB, -0.015)","(MARCKS, -0.021)","(HSD11B1, -0.023)","(COL4A5, -0.03)","(NR2F1, -0.033)","(DIO2, -0.033)","(AGT, -0.039)","(RNASE1, -0.053)","(IVD, -0.098)","(GSTA4, -0.108)","(NRIP1, -0.129)","(HS3ST1, -0.131)","(OGN, -0.141)","(DCN, -0.141)"]
[79,"LEU UP Peng at al 2002",121,0.075,0.356,1,"(TFF3, 0.747)","(HIST1H2BE, 0.697)","(MT2A, 0.576)","(CKB, 0.477)","(PYCR1, 0.402)","(MTHFD2, 0.366)","(C6orf80, 0.341)","(PCK2, 0.31)","(HDAC5, 0.275)","(XPOT, 0.274)","(PDE6D, 0.263)","(ALDH2, 0.253)","(SPAG9, 0.227)","(SURF1, 0.224)","(UNC119, 0.213)","(UBE2N, 0.204)","(C22orf1, 0.184)","(CEBPB, 0.181)","(CD22, 0.179)","(SLC6A11, 0.151)","(ERCC2, 0.132)","(TNFRSF7, 0.131)","(PPP2R5C, 0.126)","(DDX46, 0.124)","(IRF2, 0.119)","(SLC3A2, 0.118)","(NFE2L1, 0.111)","(POU2F3, 0.088)","(GCHFR, 0.059)","(SWAP70, 0.038)","(APBB3, 0.015)","(MTX1, 0.012)","(GPLD1, 0.01)","(AIM1, 0.008)","(BMP7, 0.007)","(VPS39, 0.007)","(ATF4, 0)","(CLCN6, 0)","(ATF5, 0)","(ISG20, 0)","(APS, 0)","(SSR2, 0)","(DAAM1, 0)","(CIRBP, 0)","(MARS, 0)","(MEF2B, 0)","(TNNT1, 0)","(MAP1LC3B, 0)","(CUTL1, 0)","(KHSRP, 0)","(PRKCBP1, 0)","(MGEA6, 0)","(MIDORI, 0)","(CARS, 0)","(BMP1, 0)","(LOC51035, 0)","(PLXNB2, 0)","(APOBEC3G, 0)","(GBF1, 0)","(NCOR1, 0)","(ITGB3BP, 0)","(BCL7A, 0)","(SUI1, 0)","(INS, 0)","(GCDH, 0)","(SIAT1, 0)","(KIAA0889, 0)","(G10, 0)","(RAB3GAP, 0)","(WARS, 0)","(CAMK1, 0)","(PHGDH, 0)","(hnRNPA3, 0)","(A2LP, 0)","(FCER2, 0)","(ANKRD15, 0)","(LRMP, 0)","(ASNS, 0)","(BNIP3L, 0)","(MUC3A, 0)","(RW1, 0)","(HMGA1, 0)","(KIAA0922, 0)","(DECR1, 0)","(AARS, 0)","(LCK, 0)","(IDH2, 0)","(BTG2, 0)","(RERE, 0)","(ASS, 0)","(CLIC4, 0)","(S100A11, 0)","(PSPH, 0)","(HAX1, 0)","(MGC2650, 0)","(CD6, 0)","(RASGRP3, 0)","(PDCD4, 0)","(SHOC2, 0)","(PSAP, 0)","(BACH1, 0)","(SLC43A1, 0)","(PCBP3, 0)","(SARS, 0)","(SIAT4C, 0)","(MAG, 0)","(MGST2, 0)","(IGHM, 0)","(PRELP, 0)","(SLC1A5, 0)","(PSCD1, 0)","(SLC1A4, 0)","(KIF2C, 0)","(PRKCABP, 0)","(TXNIP, 0)","(BMI1, 0)"]
[80,"th1th2Pathway BioCarta",19,0.076,0.361,0.70688,"(IL4R, 1.18)","(IL12RB1, 0.587)","(IL18, 0.406)","(IL12RB2, 0.337)","(HLA-DRB1, 0.327)","(IL12A, 0.294)","(CD28, 0.255)","(IFNGR1, 0.211)","(CD86, 0.189)","(TNFRSF5, 0.142)","(IL18R1, 0.127)","(TNFSF5, 0.121)","(IL12B, 0.12)","(IL2RA, 0.081)","(HLA-DRA, 0.007)","(IFNG, -0.044)","(IL4, -0.063)","(IL2, -0.084)","(IFNGR2, -0.089)"]
[80,"cell adhesion (GO:0007155)",114,0.076,0.361,0.71998,"(CLDN10, 1.08)","(SEMA5A, 0.888)","(AZGP1, 0.707)","(GNE, 0.554)","(NINJ1, 0.493)","(LU, 0.447)","(KAL1, 0.436)","(CDH16, 0.426)","(ACHE, 0.258)","(RAB13, 0.255)","(PCDHB11, 0.229)","(PTK2B, 0.225)","(EFNB1, 0.222)","(TSC1, 0.218)","(CIB1, 0.217)","(SELP, 0.213)","(CTNND2, 0.192)","(SCAM-1, 0.183)","(HAS1, 0.152)","(STAB1, 0.146)","(CD164, 0.134)","(CNTN6, 0.125)","(DSC3, 0.115)","(CCL4, 0.108)","(VWF, 0.095)","(CCR1, 0.075)","(CELSR1, 0.057)","(LY6D, 0.045)","(BYSL, 0.038)","(CD9, 0.015)","(MLLT4, 0)","(MCAM, 0)","(CDH3, 0)","(FPRL1, 0)","(PCDHB3, 0)","(TNC, 0)","(ERBB2IP, 0)","(ARF6, 0)","(MFGE8, 0)","(CCL11, 0)","(DGCR6, 0)","(SSPN, 0)","(MADCAM1, 0)","(EDG1, 0)","(PCDHA6, 0)","(CASK, 0)","(LRRN5, 0)","(CLDN1, 0)","(ATP2A2, 0)","(CDH2, 0)","(RS1, 0)","(CD36, 0)","(CD97, 0)","(LOXL2, 0)","(DDR1, 0)","(ALCAM, 0)","(CDH15, 0)","(CXCR3, 0)","(PCDHA2, 0)","(CCL2, 0)","(CD226, 0)","(OPCML, 0)","(CDH4, 0)","(ARVCF, 0)","(RHOB, 0)","(PTPRF, 0)","(APBA1, 0)","(CDH6, 0)","(NLGN3, 0)","(APC, 0)","(SELL, 0)","(MUCDHL, 0)","(PPFIBP1, 0)","(DSC2, 0)","(DSCAM, 0)","(PTPRU, 0)","(CCR8, 0)","(NPHS1, 0)","(TYRO3, 0)","(CHST10, 0)","(CCR3, 0)","(LGALS4, 0)","(SELPLG, 0)","(ROBO1, 0)","(CDH17, 0)","(TROAP, 0)","(ARHGAP5, 0)","(SEMA4D, 0)","(FAT, 0)","(ITGB3BP, 0)","(PCDHA5, 0)","(GPR56, 0)","(PCDHB12, 0)","(CDH8, 0)","(EMILIN1, 0)","(DDR2, 0)","(ZYX, 0)","(CD96, 0)","(CXCL12, 0)","(CX3CR1, 0)","(SPOCK, 0)","(PCDHA10, 0)","(PCDHA3, 0)","(POSTN, 0)","(CCL5, 0)","(FEZ1, 0)","(EMR1, 0)","(MMRN1, 0)","(VTN, 0)","(PCDHB6, 0)","(CD72, 0)","(CDH13, 0)","(SPG7, 0)","(BAI1, 0)"]
[82,"copper ion homeostasis (GO:0006878)",4,0.078,0.369,0.9249,"(MT2A, 2.046)","(APP, 0.354)","(ATOX1, 0.353)","(CP, 0.123)"]
[82,"negative regulation of cell growth (GO:0030308)",8,0.078,0.369,0.97425,"(OKL38, 1.233)","(MT3, 1.231)","(PPP2R1B, 0.326)","(APBB2, 0.147)","(DLC1, 0.051)","(APBB1, 0.011)","(DCBLD2, -0.02)","(TP53, -0.027)"]
[84,"innate immune response (GO:0045087)",2,0.08,0.382,0.74084,"(DEFB1, 1.937)","(SFTPD, 0.265)"]
[85,"ethanol oxidation (GO:0006069)",4,0.081,0.387,0.78844,"(ADH7, 2.621)","(ADH5, 0.255)","(ADH1B, 0.149)","(ADH6, -0.091)"]
[86,"MAP00260 Glycine serine and threonine metabolism GenMAPP",24,0.082,0.391,0.97318,"(MAOB, 1.288)","(ALAS1, 0.891)","(AMT, 0.861)","(SHMT1, 0.393)","(TARS, 0.293)","(MAOA, 0.157)","(DAO, 0.129)","(AGXT, 0.112)","(AOC3, 0.084)","(GAMT, 0.044)","(CBS, 0.015)","(SDS, 0.014)","(BHMT, -0.006)","(KIAA0335, -0.015)","(DLD, -0.024)","(GARS, -0.031)","(ABP1, -0.033)","(HBG2, -0.035)","(SARS, -0.043)","(LOC56901, -0.084)","(AOC2, -0.107)","(GLDC, -0.148)","(PISD, -0.17)","(SHMT2, -0.182)"]
[86,"protein repair (GO:0030091)",2,0.082,0.391,1,"(SEPX1, 0.022)","(MSRB2, 0)"]
[88,"calcium-independent cell-cell adhesion (GO:0016338)",15,0.083,0.394,0.58619,"(CLDN10, 2.028)","(CLDN7, 0.847)","(CLDN9, 0.408)","(CLDN8, 0.232)","(CLDN1, 0.154)","(CLDN17, 0.076)","(CLDN4, 0.005)","(CLDN18, -0.006)","(CLDN11, -0.021)","(CLDN3, -0.022)","(CLDN16, -0.025)","(CLDN5, -0.036)","(CLDN15, -0.058)","(CLDN6, -0.109)","(CLDN14, -0.134)"]
[88,"regulation of DNA recombination (GO:0000018)",3,0.083,0.394,0.91885,"(KPNA2, 1.482)","(KPNA1, 0.44)","(IL7R, 0.337)"]
[88,"eponfkbPathway The cytokine erythropoietin (Epo) prevents stress-induced neuronal apoptosis by stimulating anti-apoptotic pathways through JAK2 kinase and NF-kB.",11,0.083,0.394,1,"(NFKBIA, 1.31)","(NFKB1, 1.073)","(HIF1A, 0.697)","(EPOR, 0.443)","(EPO, 0.045)","(GRIN1, 0.004)","(SOD2, -0.019)","(ARNT, -0.042)","(CDKN1A, -0.087)","(JAK2, -0.107)","(RELA, -0.215)"]
[91,"lamellipodium biogenesis (GO:0030032)",2,0.084,0.394,0.89721,"(RAC1, 0.916)","(ARFIP2, 0.827)"]
[91,"immune cell chemotaxis (GO:0030595)",4,0.084,0.394,0.9655,"(CX3CL1, 2.677)","(SPP1, 0.248)","(PF4, 0.107)","(IL10, 0.075)"]
[93,"fxrPathway The nuclear receptor transcription factors FXR and LXR are activated by cholesterol metabolites and regulate cholesterol homeostasis.",6,0.085,0.401,0.77778,"(FABP6, 2.363)","(RXRA, 0.872)","(LDLR, 0.321)","(NR1H3, -0.093)","(NR0B2, -0.11)","(NR1H4, -0.266)"]
[93,"transcription initiation from RNA polymerase III promoter (GO:0006384)",3,0.085,0.401,0.93236,"(SNAPC5, 1.299)","(BRF1, 0.711)","(GTF3C4, 0.388)"]
[95,"ketonebodiesPathway BLACK",4,0.087,0.407,0.88112,"(BDH, 1.136)","(HMGCS2, 1.125)","(HMGCL, 0.125)","(ACAT1, -0.076)"]
[96,"cotranslational protein targeting to membrane (GO:0006613)",5,0.088,0.411,0.93029,"(SRP19, 1.263)","(SSR1, 0.368)","(SSR2, 0.35)","(SRP14, 0.223)","(TRAM1, -0.005)"]
[97,"intracellular sequestering of iron ion (GO:0006880)",2,0.09,0.418,0.87706,"(FTH1, 3.096)","(SRI, 0.077)"]
[97,"MYC MUT BLACK",5,0.09,0.418,1,"(TIPARP, 1.864)","(NNMT, 0.837)","(HEAB, 0.256)","(GSS, -0.043)","(RAN, -0.22)"]
[99,"epidermis development (GO:0008544)",55,0.091,0.422,0.56813,"(KRT14, 0.756)","(CTGF, 0.684)","(COL7A1, 0.576)","(KRT15, 0.547)","(PTCH2, 0.434)","(TGM5, 0.315)","(KRT10, 0.227)","(LAMA3, 0.218)","(LAMC2, 0.213)","(COL17A1, 0.213)","(SPRR1A, 0.212)","(STS, 0.2)","(FABP5, 0.191)","(PPARD, 0.188)","(BTD, 0.163)","(KRT13, 0.145)","(HOXB13, 0.138)","(LAMB3, 0.136)","(EVPL, 0.134)","(CRABP2, 0.125)","(POU2F3, 0.124)","(FGF7, 0.108)","(ATP2C1, 0.101)","(WAS, 0.085)","(ALOX12B, 0.04)","(GJB5, 0.023)","(SPRR1B, 0.023)","(DCT, 0.021)","(KRT5, 0.021)","(DSP, 0.02)","(EMP1, 0)","(KRTHB3, 0)","(PTHLH, 0)","(FOXN1, 0)","(KRTHB5, 0)","(KRTHA4, 0)","(KRT2A, 0)","(S100A7, 0)","(EDAR, 0)","(KRT17, 0)","(UGCG, 0)","(BNC1, 0)","(KRT1, 0)","(KRTHA1, -0.004)","(KRTHA2, -0.023)","(KLK5, -0.025)","(FLOT2, -0.035)","(ALDH3A2, -0.036)","(COL1A1, -0.04)","(ATP2A2, -0.061)","(CALML5, -0.102)","(KRT9, -0.117)","(SCEL, -0.146)","(KLK7, -0.172)","(KRT16, -0.196)"]
[99,"response to metal ion (GO:0010038)",3,0.091,0.422,0.84903,"(MT1X, 2.565)","(MTL5, 0.108)","(NDRG1, -0.105)"]
[99,"fructose 6-phosphate metabolism (GO:0006002)",4,0.091,0.422,0.89975,"(GFPT1, 1.724)","(MPI, 0.802)","(GFPT2, -0.009)","(PFKL, -0.06)"]
[99,"protein localization (GO:0008104)",5,0.091,0.422,0.94961,"(AKAP10, 0.731)","(C6orf82, 0.604)","(AKAP7, 0.521)","(CD81, 0.458)","(BIN3, -0.004)"]
[99,"CR HORMONAL FUNCTIONS PNAS 2008",12,0.091,0.422,1,"(NKX3-1, 1.428)","(BAG1, 0.976)","(GIP, 0.649)","(ADRBK1, 0.411)","(STAR, 0.235)","(PGR, 0.104)","(THRB, 0.037)","(ESR1, -0.013)","(HSD17B2, -0.031)","(FSHR, -0.059)","(SSTR2, -0.078)","(THRA, -0.125)"]
[104,"MAP00195 Photosynthesis GenMAPP",19,0.092,0.426,0.54323,"(ATP6V0A4, 0.894)","(ATP6V1D, 0.731)","(ATP6V1B1, 0.691)","(ATP5E, 0.353)","(ATP6V0B, 0.351)","(ATP6V1F, 0.267)","(ATP6V0C, 0.193)","(ATP6AP1, 0.17)","(ATP6V1A, 0.151)","(ATP6V1G2, 0.12)","(ATP6V1E1, 0.093)","(ATP6V0D1, 0.061)","(ATP6V1G1, 0.058)","(ATP6V0E, -0.058)","(ATP6V0A1, -0.064)","(MPP5, -0.08)","(ATP6V1B2, -0.091)","(ATP6V1C1, -0.103)","(FDXR, -0.105)"]
[104,"synaptic transmission, cholinergic (GO:0007271)",7,0.092,0.426,0.91717,"(NQO1, 2.632)","(CHRNA10, 0.28)","(CHRNE, 0.225)","(APOE, 0.069)","(CHRNB4, 0.007)","(CHRNB3, -0.016)","(CHRNB1, -0.077)"]
[106,"positive regulation of axonogenesis (GO:0050772)",2,0.095,0.437,0.83704,"(SLIT2, 3.029)","(ROBO1, -0.095)"]
[107,"MAP00330 Arginine and proline metabolism GenMAPP",39,0.096,0.444,0.89634,"(MAOB, 1.142)","(CKB, 0.732)","(PYCR1, 0.661)","(SMS, 0.475)","(CKMT2, 0.422)","(ALDH2, 0.398)","(NOS2A, 0.334)","(SAT, 0.317)","(P4HB, 0.207)","(GOT2, 0.175)","(P4HA1, 0.147)","(DAO, 0.141)","(AMD1, 0.085)","(ARG2, 0.065)","(ASS, 0.052)","(AGMAT, 0.052)","(GAMT, 0.044)","(RARS, 0.037)","(MAOA, 0.03)","(AOC3, 0.019)","(CKM, 0)","(ABP1, 0)","(AOC2, -0.003)","(ASL, -0.008)","(VTI1B, -0.008)","(EPRS, -0.016)","(ODC1, -0.033)","(GLUD1, -0.034)","(ALDH1B1, -0.048)","(OAT, -0.059)","(ARG1, -0.075)","(OTC, -0.076)","(ALDH3A2, -0.078)","(ALDH1A1, -0.079)","(NOS1, -0.083)","(CKMT1, -0.085)","(NOS3, -0.1)","(CPS1, -0.129)","(GOT1, -0.155)"]
[107,"neurotransmittersPathway BLACK",6,0.096,0.444,0.99684,"(GAD1, 0.947)","(DBH, 0.845)","(TH, 0.583)","(PNMT, 0.53)","(HDC, 0.101)","(TPH1, -0.207)"]
[109,"MAP00760 Nicotinate and nicotinamide metabolism BLACK",4,0.097,0.444,1,"(NP, 1.57)","(NNMT, 0.833)","(QPRT, 0.079)","(AOX1, -0.182)",{"$nulls":112},"(SLC1A3, 0)","(NTSR1, 0)","(GRIK2, 0)","(EDG7, 0)","(DRD4, 0)","(LAMB2, 0)","(PCDHB6, 0)","(PDE7B, 0)","(OPRK1, 0)","(GPR8, 0)","(KCNMB4, 0)","(GRM3, 0)","(CACNA1B, 0)","(SCN10A, 0)","(SYN1, 0)"]
[110,"leukotriene metabolism (GO:0006691)",2,0.098,0.451,0.67504,"(CYP4F3, 2.341)","(CYP4F2, 0.049)"]
[110,"protein amino acid ADP-ribosylation (GO:0006471)",7,0.098,0.451,0.82047,"(SIRT3, 1.754)","(SIRT6, 1.313)","(ART1, 0.072)","(SIRT5, -0.022)","(SIRT4, -0.033)","(SIRT1, -0.039)","(ART3, -0.053)"]
[110,"hindbrain development (GO:0030902)",2,0.098,0.451,0.88674,"(PBX1, 0.982)","(PBX3, 0.643)"]
[113,"negative regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043124)",3,0.099,0.451,0.95008,"(ZA20D1, 0.977)","(TNFAIP3, 0.712)","(RHOH, 0.353)"]
[114,"MAP00603 Globoside metabolism GenMAPP",10,0.1,0.453,0.77202,"(SIAT4A, 1.332)","(NAGA, 0.755)","(FUT3, 0.64)","(FUT6, 0.222)","(HEXA, 0.168)","(FUT2, 0.058)","(FUT1, -0.022)","(GLA, -0.048)","(HEXB, -0.167)","(FUT5, -0.185)"]
[114,"I-kappaB phosphorylation (GO:0007252)",2,0.1,0.453,0.92272,"(PRDX4, 2.229)","(CHUK, 0.124)"]
[116,"insulin receptor signaling pathway (GO:0008286)",9,0.102,0.455,0.71024,"(AP3S1, 1.235)","(PIK3R3, 1.082)","(GAB1, 0.303)","(SORBS1, 0.227)","(PDPK1, 0.155)","(IGF2, 0.012)","(IGF1R, -0.021)","(PIK3R2, -0.076)","(GRB10, -0.124)"]
[116,"regulation of phosphorylation (GO:0042325)",2,0.102,0.455,0.8617,"(BARD1, 2.022)","(PIK3R2, 0.111)"]
[118,"nucleotide metabolism (GO:0009117)",2,0.103,0.455,1,"(REXO2, 0.014)","(FHIT, 0)"]
[119,"prostaglandin metabolism (GO:0006693)",3,0.104,0.455,0.68312,"(AKR1C3, 3.091)","(CYP4F8, 0.164)","(PTGES, -0.258)"]
[119,"AR MOUSE PLUS TESTO FROM NETAFFX na",61,0.104,0.455,0.75406,"(AGR2, 0.912)","(CYP2A13, 0.78)","(CYP2A6, 0.745)","(ERP70, 0.608)","(FKBP11, 0.497)","(CYP3A5, 0.388)","(SC4MOL, 0.295)","(UGT2B4, 0.292)","(FDFT1, 0.279)","(GPC1, 0.184)","(MAN1A1, 0.182)","(GFRA1, 0.166)","(ISYNA1, 0.154)","(CYP2B6, 0.146)","(CYB561, 0.112)","(ARAF1, 0.103)","(KCNK1, 0.098)","(NCF2, 0.094)","(KLRB1, 0.07)","(TCF7, 0.019)","(CLU, 0.017)","(CYP3A7, 0.014)","(RAMP3, 0.005)","(GJB3, 0)","(ADRA2C, 0)","(PTPRO, 0)","(BTG3, 0)","(GPX5, 0)","(FLJ21934, 0)","(RRM1, 0)","(FDPS, 0)","(GLDC, 0)","(ACE, 0)","(AGPAT3, 0)","(EAF2, 0)","(ENPP1, 0)","(ADAM7, 0)","(GSTM1, 0)","(MYOM2, 0)","(CYP3A4, 0)","(GLUL, 0)","(PEMT, 0)","(FKBP5, 0)","(NUCB2, 0)","(EBP, 0)","(KIAA0251, 0)","(AR, 0)","(KCNK7, 0)","(STMN1, 0)","(UGT2B17, 0)","(CA2, 0)","(UGT2B28, 0)","(CYP2C9, 0)","(ADCY8, 0)","(INDO, -0.014)","(CA4, -0.017)","(UGT2B15, -0.019)","(ISG20, -0.022)","(CYP3A43, -0.049)","(TPMT, -0.145)","(ALPL, -0.192)"]
[119,"regulation of transcriptional preinitiation complex formation (GO:0045898)",2,0.104,0.455,0.88674,"(PBX1, 1.007)","(PBX3, 0.664)"]
[122,"chloride transport (GO:0006821)",3,0.109,0.464,0.99001,"(FXYD1, 2.319)","(FXYD3, 0.06)","(GLRA3, -0.011)"]
[123,"methionine metabolism (GO:0006555)",2,0.111,0.469,0.87583,"(SMS, 1.693)","(MSRA, 0.152)"]
[124,"defense response to bacteria (GO:0042742)",7,0.112,0.469,0.7678,"(CAMP, 1.244)","(NOS2A, 0.856)","(STAB1, 0.728)","(TLR3, 0.17)","(LALBA, -0.026)","(PFC, -0.136)","(TLR6, -0.156)"]
[124,"embryo implantation (GO:0007566)",5,0.112,0.469,0.86874,"(SCGB1A1, 2.615)","(PPARD, 0.315)","(TRO, 0.205)","(RPL29, -0.214)","(PRLR, -0.258)"]
[124,"positive regulation of interferon-gamma biosynthesis (GO:0045078)",3,0.112,0.469,0.97829,"(TNFRSF7, 0.899)","(EBI3, 0.432)","(IL12B, 0.357)"]
[127,"defense response (GO:0006952)",36,0.113,0.469,0.86167,"(TFF3, 1.136)","(TFF1, 0.847)","(INHBB, 0.586)","(P2RY11, 0.331)","(IL17RB, 0.278)","(CEBPE, 0.26)","(WAS, 0.187)","(IRAK1, 0.173)","(CYSLTR1, 0.164)","(MST1R, 0.16)","(MLF2, 0.158)","(TNIP1, 0.134)","(PTPRCAP, 0.13)","(PSG3, 0.107)","(CSF3R, 0.083)","(SIVA, 0.067)","(TIAL1, 0.051)","(RNASE6, 0.011)","(HRMT1L2, 0)","(FOXN1, 0)","(KCNN4, 0)","(NCF4, -0.002)","(CAMLG, -0.005)","(GATA3, -0.008)","(HP, -0.008)","(MPO, -0.013)","(SOCS6, -0.015)","(CD79A, -0.017)","(CD69, -0.021)","(LY6E, -0.021)","(SP140, -0.04)","(TFF2, -0.043)","(APOH, -0.066)","(CD83, -0.072)","(INHBA, -0.083)","(CD48, -0.118)"]
[128,"citrate metabolism (GO:0006101)",2,0.115,0.469,0.91966,"(ACLY, 2.195)","(ACO2, -0.17)"]
[128,"MAP00670 One carbon pool by folate GenMAPP",12,0.115,0.469,1,"(AMT, 1.277)","(MTHFD2, 0.957)","(SHMT1, 0.593)","(GART, 0.561)","(DHFR, 0.203)","(MTR, 0.083)","(ATIC, -0.034)","(FTHFD, -0.042)","(LOC56901, -0.079)","(TYMS, -0.16)","(MTHFD1, -0.194)","(SHMT2, -0.205)"]
[130,"membrane protein ectodomain proteolysis (GO:0006509)",6,0.116,0.469,0.8929,"(BACE2, 1.027)","(BACE1, 0.694)","(NCSTN, 0.479)","(ARTS-1, 0.385)","(PSEN1, 0.129)","(PSEN2, -0.206)"]
[131,"MAP00190 Oxidative phosphorylation GenMAPP",45,0.117,0.469,0.55761,"(ATP6V0A4, 0.676)","(COX6A1, 0.599)","(ATP12A, 0.538)","(ATP6V1B1, 0.447)","(ATP6V1D, 0.435)","(ATP7A, 0.292)","(ATP6V0B, 0.252)","(ATP7B, 0.243)","(SDHB, 0.198)","(ATP4A, 0.197)","(ATP6V1F, 0.188)","(ATP5E, 0.176)","(COX7A1, 0.171)","(COX5B, 0.165)","(COX7B, 0.157)","(COX7A2, 0.156)","(ATP6V1A, 0.131)","(NDUFS1, 0.116)","(COX4I1, 0.107)","(ATP6V0C, 0.101)","(ATP6V1E1, 0.083)","(COX6A2, 0.073)","(ATP6AP1, 0.072)","(COX5A, 0.044)","(SDHA, 0.036)","(COX7C, 0.014)","(ATP6V1B2, 0)","(ATP6V1G2, 0)","(ATP4B, 0)","(COX6C, 0)","(NFKBIL2, 0)","(MPP5, 0)","(COX6B, 0)","(ATP6V0D1, -0.011)","(UQCRB, -0.014)","(ATP6V0E, -0.014)","(ATP6V1C1, -0.03)","(NDUFV2, -0.034)","(ATP6V1G1, -0.048)","(NDUFA5, -0.052)","(ATP6V0A1, -0.054)","(ZNF183, -0.065)","(UQCRFS1, -0.094)","(UQCRC1, -0.107)","(UQCRC2, -0.125)"]
[132,"MAP00561 Glycerolipid metabolism GenMAPP",47,0.118,0.469,0.54716,"(ADH7, 1.163)","(AKR1B1, 1.112)","(AGPS, 0.443)","(ACHE, 0.411)","(PLA2G4A, 0.402)","(ALDH2, 0.39)","(GPD1, 0.276)","(LPL, 0.251)","(DGKE, 0.176)","(ALPPL2, 0.163)","(DGKQ, 0.142)","(CPT2, 0.136)","(PLA2G1B, 0.132)","(GPD2, 0.127)","(PNLIPRP1, 0.085)","(PAFAH1B1, 0.075)","(ADH5, 0.07)","(ADH1C, 0.064)","(LIPC, 0.044)","(TPI1, 0.041)","(EKI1, 0.04)","(DGAT1, 0.038)","(SERPINB1, 0.028)","(PLA2G5, 0.02)","(GK, 0.013)","(ALDH3A2, 0)","(ALDH1B1, 0)","(ADH6, 0)","(PNLIP, 0)","(DGKG, 0)","(GLB1, 0)","(ADH1B, 0)","(ALDH1A1, 0)","(PLA2G2A, -0.005)","(CEL, -0.006)","(PISD, -0.008)","(CHAT, -0.009)","(ALPP, -0.012)","(PCYT1A, -0.014)","(PNLIPRP2, -0.019)","(ALPL, -0.026)","(ALPI, -0.031)","(GLA, -0.036)","(ADH1A, -0.084)","(DGKA, -0.09)","(PAFAH2, -0.104)","(CPT1A, -0.108)"]
[133,"pepiPathway BioCarta",6,0.119,0.469,0.88536,"(SLPI, 2.244)","(ELA2A, 0.218)","(ELA2, 0.055)","(GRN, 0.006)","(ELA3B, -0.017)","(IL8, -0.063)"]
[133,"glycolysis (GO:0006096)",4,0.119,0.469,0.90791,"(ALDOA, 2.433)","(HK1, 0.06)","(PGK1, -0.076)","(ALDOB, -0.116)"]
[135,"response to drug (GO:0042493)",11,0.121,0.469,0.9543,"(ABCC1, 2.019)","(CTPS, 0.53)","(ABCB1, 0.451)","(ABCA3, 0.334)","(SEMA3C, 0.176)","(MVP, 0.102)","(ABCB4, 0.011)","(SCN11A, -0.016)","(ABCG2, -0.034)","(ABCC6, -0.118)","(RAB6C, -0.144)"]
[136,"positive regulation of phagocytosis (GO:0050766)",4,0.122,0.469,0.73843,"(GATA2, 1.247)","(AHSG, 0.443)","(AZU1, 0.266)","(SFTPD, 0.14)"]
[137,"axon guidance (GO:0007411)",17,0.123,0.474,0,"(SLIT1, 1.467)","(KAL1, 0.961)","(EVL, 0.631)","(NRXN3, 0.193)","(FEZ1, 0.093)","(NRXN1, 0.091)","(UNC5C, 0.064)","(NRP2, 0.054)","(FEZ2, 0.021)","(GNAO1, 0.018)","(UBA52, 0.009)","(SPON2, 0.004)","(SEMA3B, -0.057)","(SIAH1, -0.08)","(OPHN1, -0.089)","(SEMA4F, -0.128)","(NRP1, -0.134)"]
[137,"nucleoside transport (GO:0015858)",3,0.123,0.474,0.82463,"(SLC29A1, 2.051)","(SLC29A2, 0.108)","(SLC28A1, -0.091)"]
[139,"Rho protein signal transduction (GO:0007266)",17,0.126,0.477,0.38993,"(ARHGEF3, 0.865)","(ARHGAP4, 0.836)","(CFL1, 0.732)","(ADRA2A, 0.528)","(TSC1, 0.388)","(ARHGEF1, 0.13)","(ROCK1, 0.124)","(ARHGAP5, 0.092)","(RHOA, 0.058)","(RHOG, 0.036)","(ARHGDIG, 0.036)","(ARHGAP1, -0.018)","(ARHGDIA, -0.023)","(RHOD, -0.024)","(ARHGDIB, -0.067)","(LIMK1, -0.138)","(ARHGEF11, -0.151)"]
[139,"regulation of exit from mitosis (GO:0007096)",2,0.126,0.477,0.72632,"(CYB561D2, 0.94)","(CDC23, 0.432)"]
[139,"Matrix Metalloproteinases BioCarta",26,0.126,0.477,0.7619,"(TIMP1, 1.257)","(MMP10, 0.894)","(MMP25, 0.412)","(MMP16, 0.4)","(TIMP3, 0.25)","(MMP7, 0.238)","(TIMP4, 0.217)","(MMP15, 0.164)","(MMP14, 0.143)","(MMP11, 0.121)","(TIMP2, 0.114)","(MMP27, 0.069)","(MMP2, 0.061)","(MMP28, 0.054)","(TNF, 0.01)","(BSG, 0.008)","(MMP8, 0.004)","(MMP17, 0)","(MMP12, -0.009)","(MMP20, -0.01)","(MMP26, -0.025)","(MMP19, -0.082)","(MMP3, -0.087)","(MMP13, -0.112)","(MMP9, -0.115)","(MMP24, -0.179)"]
[139,"rabPathway BioCarta",11,0.126,0.477,1,"(RAB11A, 1.347)","(RAB6A, 0.395)","(RAB3A, 0.339)","(RAB9A, 0.322)","(ACTA1, 0.197)","(RAB2, 0.165)","(RAB4A, 0.097)","(RAB5A, 0.022)","(RAB27A, -0.032)","(RAB1A, -0.055)","(RAB7, -0.071)"]
[143,"male meiosis (GO:0007140)",2,0.128,0.484,1,"(HSPA2, 0.009)","(PIM2, 0.001)"]
[144,"reckPathway BioCarta",9,0.129,0.484,0.8179,"(TIMP1, 1.736)","(TIMP3, 0.369)","(TIMP4, 0.266)","(MMP2, 0.2)","(MMP14, 0.188)","(TIMP2, 0.103)","(RECK, 0.029)","(HRAS, -0.021)","(MMP9, -0.151)"]
[145,"cobalamin transport (GO:0015889)",2,0.131,0.491,0.74209,"(TCN1, 2.945)","(TCN2, -0.169)"]
[145,"SA FAS SIGNALLING SigmaAldrich",9,0.131,0.491,0.81513,"(CFL1, 0.998)","(PDE6D, 0.731)","(CASP3, 0.544)","(TNFSF6, 0.101)","(BCL2, 0.091)","(TNFRSF6, 0.085)","(P11, 0.084)","(CASP8, 0.044)","(CFLAR, -0.098)"]
[145,"opsonization (GO:0008228)",2,0.131,0.491,0.96798,"(FCN2, 1.885)","(FCN1, -0.042)"]
[145,"KRAS TOP100 KNOCKDOWN Cordero et al 2005",84,0.131,0.491,1,"(INPP4B, 0.7)","(COL7A1, 0.459)","(TUFT1, 0.436)","(LAMP2, 0.409)","(EVL, 0.39)","(MATN2, 0.31)","(DFNA5, 0.303)","(ITGAV, 0.295)","(KIAA0992, 0.281)","(COL5A1, 0.277)","(COL4A1, 0.269)","(CGI-116, 0.252)","(ULK1, 0.249)","(ST5, 0.22)","(JUN, 0.209)","(PDXK, 0.204)","(PLEKHC1, 0.2)","(DKFZp434P162, 0.195)","(HSPG2, 0.189)","(TNS, 0.184)","(HGD, 0.171)","(SERPINE1, 0.139)","(CDH4, 0.12)","(SNAI1, 0.115)","(TAGLN, 0.107)","(LBH, 0.094)","(PGLS, 0.087)","(TIMP3, 0.062)","(COL1A1, 0.056)","(ACVR1B, 0.05)","(SERPINE2, 0.044)","(NCF2, 0.04)","(CHST3, 0.038)","(MUC3B, 0.03)","(MYL9, 0.024)","(ARK5, 0.017)","(ADCY7, 0)","(TGFB2, 0)","(C8orf4, 0)","(SOX4, 0)","(SPARC, 0)","(DICER1, 0)","(MAP3K8, 0)","(GPR56, 0)","(COL4A2, 0)","(IGFBP7, 0)","(C1S, 0)","(MGEA5, 0)","(EPHB2, 0)","(HSPB1, 0)","(GABARAPL1, 0)","(CALD1, 0)","(WASPIP, 0)","(TGFBI, 0)","(DKK3, 0)","(NALP1, 0)","(BMP1, 0)","(WISP2, 0)","(TPM1, 0)","(MSC, 0)","(CLDN4, 0)","(DNAJB2, 0)","(BHLHB2, 0)","(JUNB, 0)","(ATP2B4, 0)","(IGFBP3, 0)","(SLC22A5, 0)","(P4HA2, 0)","(GLIPR1, 0)","(RSU1, 0)","(NPTX1, 0)","(ECE1, 0)","(JAK1, 0)","(GADD45B, 0)","(FLRT2, 0)","(SLC16A4, 0)","(NCK2, 0)","(IGSF4, 0)","(SPOCK, 0)","(SGK, -0.009)","(ADAM19, -0.013)","(CMKOR1, -0.02)","(CCL2, -0.048)","(TMEPAI, -0.111)"]
[145,"regulation of GTPase activity (GO:0043087)",2,0.131,0.491,1,"(RAB3GAP1, 0.012)","(RAB3GAP2, 0)"]
[150,"positive regulation of JNK cascade (GO:0046330)",2,0.133,0.496,1,"(TNFRSF7, 1.185)","(HIPK2, 0.455)",{"$nulls":114},"(PTGFR, 0)","(RGS19, 0)","(GPR1, 0)","(NTSR1, 0)","(AGTRL1, 0)","(OR1D2, 0)","(GCG, 0)","(GPR23, 0)","(CCBP2, 0)","(DEFB4, 0)","(RGR, 0)","(GPR8, 0)","(TSHB, 0)","(GPR6, 0)","(CCL25, 0)","(AKT1, 0)"]
[151,"gene silencing (GO:0016458)",2,0.134,0.502,0.79406,"(SCMH1, 1.702)","(PCOLN3, 0.01)"]
[152,"salmonellaPathway BioCarta",12,0.135,0.508,1,"(ARPC1B, 0.934)","(ARPC3, 0.644)","(ARPC4, 0.58)","(RAC1, 0.444)","(ARPC1A, 0.306)","(ACTA1, 0.251)","(ACTR3, 0.22)","(WASF1, 0.113)","(WASL, 0.097)","(ARPC2, -0.11)","(CDC42, -0.113)","(ACTR2, -0.209)"]
[153,"membrane fusion (GO:0006944)",12,0.138,0.527,0,"(VAPA, 0.89)","(VAMP3, 0.524)","(OTOF, 0.454)","(BRDG1, 0.342)","(NAPA, 0.335)","(VPS4B, 0.275)","(STX11, 0.108)","(RABIF, 0.065)","(GCA, -0.106)","(NAPG, -0.11)","(GOSR2, -0.125)","(VTI1B, -0.194)"]
[153,"eye development (sensu Mammalia) (GO:0001747)",4,0.138,0.527,1,"(CYP1B1, 3.032)","(EYA2, 0.112)","(POU4F3, -0.176)","(POU4F2, -0.191)"]
[153,"pyrimidine ribonucleotide biosynthesis (GO:0009220)",2,0.138,0.527,1,"(CMPK, 0.009)","(AK5, 0)"]
[156,"eye development (GO:0001654)",2,0.139,0.527,0.99731,"(BMPR1B, 1.086)","(PAX6, 0.578)"]
[157,"GLUCO Manually Curated",31,0.141,0.533,0.60427,"(ALDOA, 1.233)","(GPI, 0.546)","(PCK2, 0.544)","(ME2, 0.415)","(ENO1, 0.288)","(GPD1, 0.268)","(CD4, 0.221)","(ALDOC, 0.207)","(GPT, 0.199)","(PGAM2, 0.169)","(GPD2, 0.112)","(ENO3, 0.096)","(MDH1, 0.087)","(FBP2, 0.072)","(PFKM, 0.071)","(TPI1, 0.028)","(GAPDS, 0)","(PCK1, -0.007)","(LDHB, -0.007)","(FBP1, -0.021)","(LDHC, -0.033)","(ENO2, -0.036)","(PC, -0.051)","(LDHA, -0.053)","(ME1, -0.056)","(BID, -0.071)","(PGK1, -0.072)","(MDH2, -0.078)","(GK, -0.087)","(ME3, -0.111)","(ALDOB, -0.139)"]
[157,"signal complex formation (GO:0007172)",5,0.141,0.533,0.85084,"(PTK2B, 0.983)","(CD3E, 0.531)","(MAPK8IP2, 0.42)","(SRC, 0.081)","(PXN, -0.166)"]
[157,"notchPathway BLACK",5,0.141,0.533,0.9,"(NOTCH1, 1.421)","(ADAM17, 0.671)","(PSEN1, 0.117)","(RBPSUH, -0.033)","(FURIN, -0.129)"]
[157,"response to hypoxia (GO:0001666)",6,0.141,0.533,0.93119,"(MT3, 1.357)","(HIF1A, 0.932)","(EGLN2, 0.041)","(EP300, 0.014)","(CREBBP, -0.018)","(ARNT2, -0.214)"]
[161,"drug resistance and metabolism BioCarta",96,0.143,0.543,0.67576,"(NQO1, 1.152)","(ABCC1, 0.962)","(CYP1A1, 0.624)","(SOD1, 0.507)","(NFKB1, 0.415)","(CYP3A5, 0.308)","(GSTP1, 0.296)","(RXRA, 0.277)","(MET, 0.267)","(CYP2E1, 0.266)","(HIF1A, 0.257)","(CYP2D6, 0.247)","(ABCC2, 0.156)","(BLMH, 0.155)","(CYP2B6, 0.151)","(ABCB1, 0.149)","(CDKN1B, 0.131)","(RB1, 0.129)","(ERBB2, 0.105)","(FOS, 0.086)","(MSH2, 0.066)","(CCNE1, 0.053)","(ABCC3, 0.049)","(ABCC5, 0.008)","(PPARD, 0.008)","(EPHX1, 0)","(NAT2, 0)","(TPMT, 0)","(TOP2B, 0)","(TOP2A, 0)","(AHR, 0)","(TYMS, 0)","(BRCA1, 0)","(RXRG, 0)","(MYC, 0)","(ERBB4, 0)","(CDK2, 0)","(DHFR, 0)","(ERCC3, 0)","(BCL2L1, 0)","(TNFRSF11A, 0)","(ERBB3, 0)","(EPHX2, 0)","(CRABP1, 0)","(GSTM1, 0)","(CCND1, 0)","(GSK3A, 0)","(CDKN2D, 0)","(PPIA, 0)","(RARB, 0)","(MGMT, 0)","(CYP2C8, 0)","(RXRB, 0)","(RARG, 0)","(SRD5A2, 0)","(CYP2C9, 0)","(PPARA, 0)","(IGF1R, 0)","(IGF2R, 0)","(RARA, 0)","(XPA, 0)","(PPARG, 0)","(NFKBIB, 0)","(BCL2, 0)","(XPC, 0)","(MLH1, 0)","(ABCC6, 0)","(CDKN2A, 0)","(RELB, 0)","(ESR1, 0)","(EGFR, 0)","(COMT, 0)","(ESR2, 0)","(RPL13A, 0)","(FGF2, 0)","(BRCA2, 0)","(MSH3, 0)","(CYP3A4, 0)","(ABCG2, 0)","(BAX, 0)","(MVP, 0)","(CYP1A2, 0)","(APC, 0)","(NFKB2, 0)","(NFKBIE, 0)","(AP1S1, 0)","(AR, 0)","(ARNT, 0)","(GAPD, 0)","(CDK4, 0)","(CDKN1A, 0)","(ELK1, 0)","(ACTB, 0)","(TP53, -0.016)","(TOP1, -0.022)","(ATM, -0.129)"]
[161,"mRNA splice site selection (GO:0006376)",7,0.143,0.543,0.9851,"(SFRS8, 1.002)","(SFRS6, 0.719)","(SFRS5, 0.667)","(SFRS9, 0.247)","(SFRS1, -0.074)","(CUGBP1, -0.112)","(FUSIP1, -0.253)"]
[163,"p53hypoxiaPathway BioCarta",20,0.144,0.549,0.39726,"(NQO1, 1.9)","(HIF1A, 0.466)","(HSPA1A, 0.433)","(CPB2, 0.404)","(ABCB1, 0.363)","(FHL2, 0.321)","(IGFBP3, 0.165)","(BAX, 0.114)","(CSNK1A1, 0.021)","(HIC1, 0.018)","(TP53, 0.012)","(NFKBIB, -0.013)","(HSPCA, -0.024)","(MAPK8, -0.029)","(ATM, -0.037)","(GADD45A, -0.055)","(MDM2, -0.08)","(CDKN1A, -0.12)","(AKT1, -0.133)","(CSNK1D, -0.135)"]
[163,"gonad development (GO:0008406)",2,0.144,0.549,0.92617,"(MKKS, 1.3)","(HMGCR, 0.384)"]
[165,"Notch signaling pathway (GO:0007219)",5,0.146,0.555,0.96338,"(NOTCH1, 1.291)","(NOTCH4, 1.004)","(POFUT1, -0.109)","(NOTCH2, -0.113)","(DLL3, -0.15)"]
[165,"positive regulation of anti-apoptosis (GO:0045768)",2,0.146,0.555,0.98548,"(CD28, 0.838)","(OPA1, 0.445)"]
[165,"EMT UP Jechlinger et al 2003",55,0.146,0.555,1,"(CYP1B1, 1.476)","(SLPI, 1.039)","(MTHFD2, 0.523)","(GALK1, 0.494)","(HIF1A, 0.326)","(SLC3A2, 0.263)","(RRAS, 0.202)","(GAS1, 0.184)","(SNAI1, 0.181)","(SDC2, 0.156)","(FMO1, 0.151)","(DAB2, 0.138)","(PPIC, 0.135)","(PHGDH, 0.109)","(VLDLR, 0.107)","(MMP2, 0.104)","(PROCR, 0.089)","(IFITM3, 0.086)","(PRSS11, 0.049)","(PCOLCE, 0.047)","(S100A8, 0.043)","(VIM, 0.025)","(IFIT1, 0.018)","(BCL3, 0.013)","(CTSZ, 0.009)","(G1P2, 0.005)","(CD68, 0.002)","(ADSS, 0)","(DCN, 0)","(PDGFRA, 0)","(DDR2, 0)","(SPARC, 0)","(ADA, 0)","(CXCL5, 0)","(IRF7, 0)","(COL6A2, 0)","(SRM, 0)","(PLA2G7, 0)","(RNASET2, 0)","(CDH2, 0)","(UPP1, 0)","(INHBA, 0)","(COL6A1, 0)","(ASNS, 0)","(CMKOR1, -0.004)","(STAT1, -0.007)","(TNC, -0.019)","(PDGFRB, -0.023)","(PTGS1, -0.025)","(MMP12, -0.026)","(CDH15, -0.038)","(PMP22, -0.042)","(B2M, -0.044)","(IL11, -0.049)","(MMP13, -0.166)"]
[168,"GTP biosynthesis (GO:0006183)",2,0.147,0.561,0.89038,"(GUK1, 2.165)","(IMPDH1, -0.209)"]
[169,"glycoprotein biosynthesis (GO:0009101)",2,0.148,0.564,0.89732,"(MAN2A1, 0.742)","(TNIP1, 0.701)"]
[170,"mammary gland development (GO:0030879)",3,0.149,0.567,0.75472,"(NOTCH4, 1.336)","(ERBB2, 0.51)","(TDGF1, 0.015)"]
[170,"neurotransmitter uptake (GO:0001504)",3,0.149,0.567,0.9309,"(SLC6A8, 1.228)","(SLC6A4, 0.194)","(SLC1A3, 0.176)"]
[172,"sulfur metabolism (GO:0006790)",7,0.15,0.573,0.93281,"(CHST4, 1.693)","(CHST3, 0.54)","(CHST7, 0.299)","(CHST8, 0.152)","(CHST5, 0.058)","(CHST6, -0.096)","(CHST2, -0.244)"]
[172,"glycine catabolism (GO:0006546)",3,0.15,0.573,1,"(AMT, 2.081)","(GCSH, 0.129)","(GLDC, -0.215)"]
[174,"germ cell migration (GO:0008354)",3,0.152,0.583,0.93872,"(PPAP2B, 0.966)","(PPAP2A, 0.562)","(HMGCR, 0.24)"]
[174,"reelinPathway BioCarta",7,0.152,0.583,0.94138,"(LRP8, 1.394)","(DAB1, 0.716)","(FYN, 0.309)","(VLDLR, 0.228)","(RELN, 0.11)","(CDK5, -0.095)","(CDK5R1, -0.276)"]
[174,"ST Tumor Necrosis Factor Pathway Signalling Transduction KE",29,0.152,0.583,1,"(NFKBIA, 0.876)","(NFKB1, 0.712)","(TRADD, 0.649)","(JUN, 0.333)","(BIRC3, 0.286)","(CASP3, 0.281)","(TNFAIP3, 0.258)","(TNFRSF1A, 0.185)","(NFKBIL1, 0.185)","(BIRC2, 0.161)","(TRAF2, 0.135)","(NFKB2, 0.132)","(NR2C2, 0.119)","(CASP8, 0.069)","(MAP3K7, 0.018)","(BAG4, 0.011)","(RIPK1, 0)","(MAP3K3, -0.005)","(RALBP1, -0.006)","(NFKBIB, -0.007)","(TNF, -0.013)","(IKBKG, -0.015)","(MAP2K4, -0.036)","(CFLAR, -0.052)","(HRB, -0.059)","(NFKBIE, -0.108)","(NFKBIL2, -0.11)","(TNFRSF1B, -0.121)","(FADD, -0.146)"]
[174,"CR TRANSPORT OF VESICLES PNAS 2015",24,0.152,0.583,1,"(RAB11A, 1.004)","(RAB5B, 0.555)","(RAB13, 0.46)","(RAB6A, 0.285)","(RAB3B, 0.266)","(PIK3C3, 0.21)","(RAB3A, 0.196)","(RAB2, 0.162)","(RAB5C, 0.108)","(RAB4A, 0.076)","(AP2M1, 0.07)","(RAB27A, 0.037)","(RAB27B, 0.032)","(ACTR1A, -0.009)","(AP3D1, -0.01)","(RAB7, -0.029)","(GOLGA4, -0.034)","(RAB33A, -0.035)","(RAB7L1, -0.036)","(RAB1A, -0.038)","(RAB26, -0.077)","(RAB5A, -0.081)","(RAB31, -0.115)","(RAB2L, -0.159)"]
[174,"arenrf2Pathway Nrf1 and nrf2 are transcription factors that bind to antioxidant response elements (AREs), promoters of genes involved in oxidative damage control.",14,0.152,0.583,1,"(MAFG, 0.845)","(CREB1, 0.473)","(JUN, 0.461)","(KEAP1, 0.424)","(NFE2L2, 0.327)","(MAPK14, 0.3)","(MAFK, 0.229)","(FOS, 0.186)","(MAFF, 0.021)","(MAPK1, 0.005)","(MAPK8, -0.005)","(FXYD2, -0.062)","(PRKCA, -0.138)","(PRKCB1, -0.147)"]
[174,"MAP00530 Aminosugars metabolism GenMAPP",14,0.152,0.583,1,"(GNE, 1.263)","(RENBP, 0.956)","(GFPT1, 0.951)","(PGM3, 0.129)","(NAGLU, 0.069)","(HEXA, 0.052)","(HK3, -0.023)","(HK1, -0.053)","(GCK, -0.082)","(HK2, -0.145)","(DIA1, -0.16)","(CMAS, -0.189)","(PGM1, -0.201)","(HEXB, -0.218)"]
[180,"vesicle docking during exocytosis (GO:0006904)",6,0.154,0.595,0.87642,"(STX18, 1.243)","(VAMP3, 0.827)","(VDP, 0.188)","(CPLX2, 0.042)","(VAMP8, -0.085)","(VTI1B, -0.112)"]
[181,"ANDROGEN GENES FROM NETAFFX na",62,0.155,0.595,0.48122,"(AKR1B10, 1.512)","(SULT2B1, 0.569)","(SCGB2A1, 0.557)","(RNF14, 0.392)","(ABHD2, 0.388)","(ARSE, 0.355)","(C20orf14, 0.349)","(HSD17B8, 0.293)","(UGT2B4, 0.246)","(HSD17B3, 0.224)","(CRSP2, 0.191)","(RDH11, 0.178)","(RDH5, 0.175)","(SRD5A1, 0.138)","(AKR1C4, 0.134)","(PPAP2A, 0.127)","(RODH-4, 0.124)","(VDRIP, 0.102)","(NSD1, 0.088)","(SRD5A2, 0.08)","(RWDD1, 0.073)","(STS, 0.03)","(FLJ21934, 0.028)","(NR3C2, 0.023)","(TGFB1I1, 0.013)","(FKBP5, 0.008)","(RODH, 0)","(LCN7, 0)","(ARSD, 0)","(CRISP1, 0)","(HSD11B2, 0)","(APRIN, 0)","(UGT2B15, 0)","(AKR1D1, 0)","(TMPRSS2, 0)","(SHBG, 0)","(HSD11B1, 0)","(SULT2A1, 0)","(NR3C1, 0)","(HSD3B2, 0)","(FXR2, 0)","(FGF8, 0)","(PART1, 0)","(RAN, 0)","(AR, 0)","(C18orf1, 0)","(TMEPAI, 0)","(HSD17B2, 0)","(UGT2B17, 0)","(CRSP6, 0)","(TNRC11, 0)","(NR1I3, -0.014)","(GPX5, -0.015)","(NCOA4, -0.021)","(UGT2B28, -0.031)","(PPARBP, -0.041)","(C6orf105, -0.042)","(HSD3B1, -0.056)","(CYP11B1, -0.085)","(CYP11B2, -0.086)","(CYP19A1, -0.101)","(KIAA1093, -0.161)"]
[181,"cytokine and chemokine mediated signaling pathway (GO:0019221)",4,0.155,0.595,0.74425,"(CX3CL1, 2.718)","(PF4, 0.045)","(IRAK3, -0.159)","(SOCS5, -0.193)"]
[183,"antibacterial humoral response (sensu Vertebrata) (GO:0019733)",2,0.156,0.595,0.92318,"(NFKB1, 1.992)","(LY96, -0.115)"]
[184,"anion transport (GO:0006820)",6,0.158,0.595,1,"(SLC17A5, 0.982)","(VDAC1, 0.978)","(SLC26A3, 0.25)","(SLC4A1, 0.107)","(VDAC2, -0.064)","(SLC4A2, -0.077)"]
[185,"heme biosynthesis (GO:0006783)",8,0.159,0.595,0.86062,"(ALAS1, 1.438)","(ALAD, 0.626)","(NFE2L1, 0.476)","(COX10, 0.128)","(CPOX, -0.056)","(FECH, -0.094)","(ALAS2, -0.161)","(PPOX, -0.163)"]
[186,"myoblast fusion (GO:0007520)",3,0.16,0.595,0.90832,"(CACNA1H, 1.173)","(KCNH1, 0.406)","(ADAM12, -0.062)"]
[186,"nucleocytoplasmic transport (GO:0006913)",4,0.16,0.595,0.93197,"(NPM1, 1.187)","(ADAM10, 0.352)","(NUP205, 0.116)","(NUP98, 0.013)"]
[188,"pparPathway BLACK",4,0.161,0.595,0.95,"(RXRA, 1.095)","(PPARD, 0.271)","(PPARG, 0.258)","(PPARA, 0.185)"]
[189,"rnaPathway BioCarta",10,0.162,0.596,0.90897,"(NFKBIA, 1.364)","(NFKB1, 1.094)","(EIF2S2, 0.46)","(TP53, 0.032)","(CHUK, -0.031)","(MAP3K14, -0.106)","(EIF2S1, -0.135)","(PRKR, -0.182)","(DNAJC3, -0.205)","(RELA, -0.225)"]
[189,"interferon-gamma biosynthesis (GO:0042095)",2,0.162,0.596,0.91361,"(IL18, 1.04)","(IL12B, 0.491)"]
[191,"protein ubiquitination (GO:0016567)",7,0.164,0.598,0.88961,"(SAE1, 1.435)","(WWP1, 1.018)","(VHL, 0.089)","(MYLIP, 0.042)","(CBL, -0.07)","(UBA52, -0.107)","(MDM2, -0.146)"]
[191,"rhodopsin mediated signaling (GO:0016056)",3,0.164,0.598,0.95368,"(GRK1, 0.961)","(SAG, 0.816)","(RHO, -0.019)"]
[193,"positive regulation of apoptosis (GO:0043065)",4,0.166,0.608,0.94791,"(BARD1, 1.799)","(IGFBP3, 0.606)","(STK3, -0.087)","(STK4, -0.206)"]
[194,"estrogen biosynthesis (GO:0006703)",2,0.168,0.611,1,"(BMPR1B, 1.218)","(HSD17B2, 0.168)"]
[195,"embryonic development (GO:0009790)",8,0.169,0.611,0.399,"(NOTCH4, 0.938)","(PBX1, 0.552)","(PBX3, 0.431)","(BMP10, 0.418)","(KIF1B, 0.01)","(TDGF1, -0.003)","(ECE2, -0.023)","(MDFI, -0.112)"]
[196,"ion transport (GO:0006811)",4,0.171,0.611,0.90591,"(LASP1, 1.156)","(AKAP7, 0.583)","(GALR1, -0.014)","(PLP2, -0.049)"]
[196,"response to cold (GO:0009409)",3,0.171,0.611,1,"(GMPR, 0.899)","(CIRBP, 0.667)","(CSDA, 0.037)"]
[198,"regulation of cell growth (GO:0001558)",3,0.172,0.611,0.78513,"(TU3A, 2.368)","(CDC2L2, -0.226)","(CDC2L1, -0.304)"]
[199,"positive regulation of activated T cell proliferation (GO:0042104)",2,0.174,0.611,0.91361,"(IL18, 1.018)","(IL12B, 0.577)"]
[199,"tall1Pathway BioCarta",13,0.174,0.611,1,"(NFKB1, 0.992)","(TNFSF13, 0.852)","(TRAF5, 0.791)","(MAPK14, 0.296)","(TRAF2, 0.275)","(TRAF3, 0.139)","(CHUK, 0.04)","(TRAF6, -0.001)","(MAPK8, -0.066)","(TNFRSF17, -0.116)","(MAP3K14, -0.13)","(TNFRSF13B, -0.139)","(RELA, -0.152)"]
[201,"G1 phase of mitotic cell cycle (GO:0000080)",7,0.176,0.611,0.92308,"(TAF1, 0.797)","(E2F1, 0.358)","(CDC23, 0.339)","(CDKN1C, 0.115)","(CDK6, 0.1)","(ANAPC2, 0.093)","(DNAJA2, 0.032)"]
[202,"neuron recognition (GO:0008038)",4,0.178,0.612,0.772,"(SLIT2, 2.696)","(PCDH12, -0.111)","(OPCML, -0.17)","(HNT, -0.333)"]
[202,"relaPathway BioCarta",16,0.178,0.612,1,"(NFKBIA, 1.179)","(NFKB1, 0.911)","(TRADD, 0.88)","(TNFRSF1A, 0.313)","(HDAC3, 0.097)","(EP300, 0.025)","(RIPK1, -0.007)","(CHUK, -0.023)","(CREBBP, -0.029)","(TRAF6, -0.043)","(TNF, -0.06)","(FADD, -0.071)","(TNFRSF1B, -0.11)","(IKBKG, -0.113)","(RELA, -0.169)","(IKBKB, -0.183)"]
[204,"endocytosis (GO:0006897)",16,0.179,0.612,0.6149,"(LRP8, 1.014)","(ATP6V1H, 0.638)","(SNX4, 0.582)","(LDLR, 0.218)","(SNX2, 0.188)","(AMPH, 0.098)","(RAB5A, 0.088)","(RAB22A, 0.06)","(EPN1, 0.043)","(PSCD2, 0.023)","(ANKFY1, -0.012)","(HOOK2, -0.032)","(SNX3, -0.05)","(SNX1, -0.07)","(TSC2, -0.083)","(RAB7, -0.106)"]
[205,"GLYCOL Manually Curated",21,0.18,0.617,1,"(ALDOA, 1.443)","(GPI, 0.624)","(ENO1, 0.441)","(CD4, 0.291)","(ALDOC, 0.287)","(PGAM2, 0.258)","(FBP2, 0.129)","(ENO3, 0.088)","(PFKM, 0.05)","(TPI1, 0.05)","(HK1, -0.003)","(FBP1, -0.018)","(ENO2, -0.032)","(GAPDS, -0.037)","(PFKFB1, -0.051)","(PGK1, -0.053)","(PKM2, -0.073)","(BID, -0.127)","(ALDOB, -0.136)","(PFKFB2, -0.15)","(PGM1, -0.223)"]
[205,"mta3Pathway BioCarta",14,0.18,0.617,1,"(ALDOA, 1.605)","(TUBA3, 0.632)","(CTSD, 0.371)","(TUBA6, 0.132)","(TUBA1, 0.111)","(GREB1, 0.066)","(HSPB1, 0.061)","(TUBA8, 0.058)","(ESR1, 0.051)","(GAPD, 0.033)","(TUBA2, -0.029)","(HSPB2, -0.053)","(MTA1, -0.104)","(PDZK1, -0.17)"]
[207,"entry of virus into host cell (GO:0046718)",5,0.181,0.617,0.88785,"(WWP1, 1.134)","(ACE2, 0.405)","(CD81, 0.325)","(WWP2, 0.076)","(ITCH, -0.06)"]
[208,"deathPathway Death receptors such as Fas and DR3, 4, and 5 transduce pro-apoptotic signaling by oligomerizing to activate the caspase cascade.",32,0.182,0.622,0.89278,"(NFKBIA, 0.883)","(TRADD, 0.646)","(NFKB1, 0.636)","(TNFSF12, 0.528)","(DFFB, 0.378)","(BIRC3, 0.359)","(CASP3, 0.265)","(TRAF2, 0.202)","(BIRC2, 0.196)","(BCL2, 0.103)","(RIPK1, 0.073)","(BIRC4, 0.064)","(LMNA, 0.063)","(CASP7, 0.04)","(DFFA, 0.033)","(CASP8, 0.022)","(GAS2, 0.014)","(CASP6, 0.007)","(TNFRSF10B, 0.007)","(CFLAR, 0)","(CASP10, -0.003)","(CHUK, -0.011)","(CYCS, -0.031)","(APAF1, -0.032)","(FADD, -0.037)","(BID, -0.066)","(MAP3K14, -0.119)","(CASP9, -0.119)","(SPTAN1, -0.13)","(TNFRSF25, -0.158)","(RELA, -0.18)","(TNFSF10, -0.197)"]
[209,"oligosaccharide biosynthesis (GO:0009312)",2,0.183,0.624,0.72822,"(FUT8, 0.958)","(COG2, 0.533)",{"$nulls":114},"(CSF2, 0)","(PDGFA, 0)","(ISGF3G, 0)","(GP1BA, 0)","(LEPR, 0)","(P2RY1, 0)","(CD3D, 0)","(GP1BB, 0)","(PRL, 0)","(CLECSF6, 0)","(MPL, 0)","(CD59, 0)","(CCKBR, 0)","(IGSF6, 0)","(FADD, 0)","(BSG, 0)","(CD4, 0)","(LY96, 0)","(CD69, 0)","(CSNK1A1, 0)","(TNFRSF25, 0)","(IRAK3, 0)","(LIFR, -0.003)"]
[209,"M phase of mitotic cell cycle (GO:0000087)",2,0.183,0.624,0.97628,"(MPHOSPH6, 1.775)","(MPHOSPH9, -0.156)"]
[211,"tsp1Pathway BioCarta",7,0.186,0.624,0.98592,"(CASP3, 0.654)","(JUN, 0.499)","(FYN, 0.4)","(MAPK14, 0.396)","(FOS, 0.373)","(THBS1, 0.01)","(CD36, -0.269)"]
[212,"hemostasis (GO:0007599)",5,0.188,0.624,0.98851,"(GPI, 1.244)","(HPS4, 0.321)","(NFE2, 0.194)","(AVPR2, 0.185)","(FLI1, -0.056)"]
[212,"carm1Pathway The methyltransferase CARM1 interacts with transcription factors such as CBP/p300 and methylates histones H3 and H4.",13,0.188,0.624,1,"(RXRA, 0.712)","(CREB1, 0.479)","(CARM1, 0.427)","(PRKACB, 0.254)","(PRKAR2A, 0.249)","(NCOA3, 0.188)","(PRKAR2B, 0.163)","(RARA, 0.114)","(PRKAR1B, 0.111)","(EP300, 0.018)","(CREBBP, -0.077)","(PRKAR1A, -0.133)","(PRKACG, -0.172)"]
[214,"response to toxin (GO:0009636)",7,0.19,0.624,0,"(NQO1, 2.633)","(MPST, 0.226)","(BPHL, -0.08)","(CES1, -0.135)","(DPYS, -0.158)","(RELA, -0.206)","(ARNT2, -0.222)"]
[215,"pkcPathway BioCarta",7,0.191,0.624,0.8992,"(NFKBIA, 1.551)","(NFKB1, 1.262)","(PLCB1, -0.043)","(GNAQ, -0.084)","(PRKCB1, -0.115)","(PRKCA, -0.165)","(RELA, -0.301)"]
[216,"vobesityPathway BioCarta",7,0.192,0.625,1,"(RXRA, 0.873)","(LPL, 0.726)","(RETN, 0.223)","(PPARG, 0.126)","(NR3C1, -0.038)","(TNF, -0.058)","(HSD11B1, -0.112)"]
[216,"KRAS TOP100 CONTROL Cordero et al 2005",66,0.192,0.625,1,"(ALDH3A1, 1.435)","(CEACAM6, 0.767)","(LRP8, 0.52)","(INHBB, 0.461)","(CTSL, 0.431)","(BENE, 0.392)","(DKK1, 0.328)","(F2RL1, 0.28)","(GPD1, 0.242)","(RRM2, 0.231)","(H2AFY, 0.179)","(CALU, 0.171)","(TLOC1, 0.144)","(RNF6, 0.135)","(CRISP1, 0.094)","(EBNA1BP2, 0.062)","(ETV5, 0.06)","(WNT2, 0.053)","(FLJ20130, 0.052)","(IGF2AS, 0.051)","(APP, 0.044)","(PPP1R3A, 0.034)","(TPSD1, 0.031)","(PARD6A, 0.024)","(HAT, 0.015)","(BYSL, 0.015)","(SKB1, 0.014)","(MRPS12, 0.008)","(H3F3B, 0)","(LBR, 0)","(FLJ20241, 0)","(PARD6B, 0)","(CXCL5, 0)","(PTMA, 0)","(UTY, 0)","(TCFL4, 0)","(POLR3K, 0)","(ATP6V1B2, 0)","(CXorf1, 0)","(EIF5, 0)","(EPHB3, 0)","(MGC4606, 0)","(ARL7, 0)","(SEMA6B, 0)","(PHLDA1, 0)","(BEX1, 0)","(PDZK2, 0)","(PDE4C, 0)","(DUSP4, 0)","(RAB40C, 0)","(EPB42, 0)","(SLC9A3R2, 0)","(IRS2, 0)","(RGS2, 0)","(ODC1, 0)","(HMGA2, -0.005)","(SSX2, -0.005)","(CHIT1, -0.014)","(TEP1, -0.025)","(SSRP1, -0.032)","(UPP1, -0.04)","(TNFRSF10D, -0.041)","(KRAS2, -0.06)","(FOSL1, -0.07)","(ENTPD6, -0.081)","(SPRED2, -0.098)"]
[218,"MAP00562 Inositol phosphate metabolism GenMAPP",19,0.193,0.628,0.74938,"(INPP4B, 1.259)","(PLCG2, 0.739)","(PLCG1, 0.561)","(PIK3C2A, 0.308)","(PIK3CB, 0.254)","(PIP5K2B, 0.173)","(INPPL1, 0.132)","(PIK3C2G, 0.127)","(ITPKA, 0.007)","(IMPA1, -0.031)","(PLCD1, -0.048)","(PLCB2, -0.065)","(INPP4A, -0.069)","(INPP1, -0.098)","(PIK3C2B, -0.098)","(ITPKB, -0.118)","(PIK4CA, -0.127)","(PIK3CA, -0.179)","(PIK3CG, -0.191)"]
[219,"glutamate catabolism (GO:0006538)",2,0.194,0.628,1,"(GLUD1, 0.007)","(GLUD2, 0.001)"]
[220,"striated muscle contraction (GO:0006941)",6,0.195,0.631,0.94601,"(ALDOA, 2.147)","(PGAM2, 0.38)","(CASQ2, 0.023)","(DTNA, -0.102)","(KBTBD10, -0.268)","(SMPX, -0.282)"]
[221,"positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123)",51,0.196,0.631,0.49079,"(ECT2, 0.954)","(TRADD, 0.528)","(VAPA, 0.49)","(TRAF5, 0.424)","(BCL10, 0.414)","(ZDHHC13, 0.38)","(PLK2, 0.337)","(LGALS1, 0.233)","(ECM1, 0.195)","(PPP5C, 0.193)","(LITAF, 0.187)","(C11orf15, 0.143)","(BIRC2, 0.132)","(SECTM1, 0.123)","(FKBP1A, 0.113)","(HTR2B, 0.11)","(FLNA, 0.096)","(TRIM38, 0.084)","(PDCD11, 0.084)","(RHOA, 0.084)","(TNFRSF1A, 0.082)","(TNFRSF10B, 0.059)","(ATP2C1, 0.028)","(MAP3K3, 0.021)","(EEF1D, 0.018)","(HMOX1, 0.008)","(CFLAR, 0)","(RIPK1, 0)","(TRAF6, 0)","(CASP1, 0)","(F2R, 0)","(RFP2, 0)","(TFG, 0)","(LGALS9, 0)","(APOL3, 0)","(RHOC, 0)","(CASP8, -0.004)","(GJA1, -0.004)","(RELA, -0.008)","(IKBKE, -0.014)","(CARD4, -0.015)","(REL, -0.015)","(RIPK2, -0.031)","(EDG2, -0.042)","(PPM1A, -0.057)","(BST2, -0.085)","(MALT1, -0.108)","(LTBR, -0.119)","(MYD88, -0.126)","(FADD, -0.135)","(TNFSF10, -0.152)"]
[221,"polyamine metabolism (GO:0006595)",2,0.196,0.631,0.66844,"(SMS, 1.735)","(OAZ2, -0.367)"]
[223,"eif2Pathway Eukaryotic initiation factor 2 (EIF2) initiates translation by transferring Met-tRNA to the 40S ribosome in a GTP-dependent process.",10,0.197,0.631,0.58421,"(EIF2AK3, 1.174)","(HRI, 0.414)","(EIF2S2, 0.41)","(EIF2B5, 0.387)","(GSK3B, 0.197)","(EIF5, 0.131)","(PPP1CA, -0.047)","(PRKR, -0.089)","(EIF2S1, -0.09)","(EIF2S3, -0.23)"]
[223,"regulation of vascular permeability (GO:0043114)",2,0.197,0.631,0.75329,"(NPR1, 1.34)","(NPPB, 0.101)"]
[225,"P53 UP Kannan et al 2001",40,0.198,0.631,1,"(NINJ1, 0.803)","(ADFP, 0.584)","(NDN, 0.469)","(PMAIP1, 0.443)","(SURF1, 0.431)","(PLK3, 0.294)","(BCL6, 0.213)","(LCAT, 0.183)","(ABCA3, 0.178)","(FHL2, 0.164)","(PCNA, 0.154)","(APLP1, 0.15)","(TNFRSF6, 0.119)","(BAX, 0.114)","(BBC3, 0.109)","(SCRIB, 0.1)","(IGFBP6, 0.039)","(BAK1, 0.034)","(FEZ1, 0.022)","(DDB2, 0.015)","(ENG, 0.014)","(MAN2B1, 0.012)","(SCGB2A2, 0.011)","(CTDSP2, 0.003)","(CES2, 0)","(KIAA0247, -0.01)","(ZNF7, -0.014)","(ATF3, -0.022)","(EXT2, -0.029)","(GADD45A, -0.046)","(CSPG2, -0.049)","(CDKN1A, -0.052)","(HAN11, -0.06)","(MDM2, -0.081)","(NHLH2, -0.096)","(POMZP3, -0.097)","(BTG2, -0.166)","(SMTN, -0.171)","(TMSNB, -0.174)","(DGKA, -0.202)"]
[226,"mitochondrial electron transport, NADH to ubiquinone (GO:0006120)",15,0.199,0.631,0.50101,"(NDUFB3, 0.792)","(NDUFB4, 0.626)","(NDUFS2, 0.316)","(NDUFS3, 0.284)","(NDUFC1, 0.271)","(NDUFS1, 0.213)","(NDUFB5, 0.157)","(NDUFS5, 0.066)","(NDUFB6, 0.056)","(NDUFS8, 0.054)","(NDUFB8, 0.048)","(NDUFB2, -0.018)","(NDUFV2, -0.042)","(NDUFS6, -0.097)","(NDUFS4, -0.178)"]
[226,"nuclear organization and biogenesis (GO:0006997)",2,0.199,0.631,1,"(NUMA1, 0.005)","(ATXN7, 0.001)"]
[228,"proline biosynthesis (GO:0006561)",2,0.2,0.631,1,"(PYCR1, 0.01)","(ALDH18A1, 0)"]
[228,"B cell proliferation (GO:0042100)",2,0.2,0.631,1,"(TNFRSF7, 0.006)","(CD40LG, 0.001)"]
[230,"chromatin remodeling (GO:0006338)",12,0.201,0.632,0.68689,"(SMARCD3, 0.74)","(HDAC5, 0.699)","(TNP1, 0.294)","(GCN5L2, 0.272)","(SMARCC1, 0.216)","(SMARCA5, 0.164)","(TAF6L, 0.096)","(SMARCA1, 0.054)","(HBXAP, -0.031)","(SMARCD2, -0.053)","(SMARCC2, -0.131)","(SUV39H2, -0.191)"]
[230,"mitotic spindle checkpoint (GO:0007094)",3,0.201,0.632,0.92012,"(BUB3, 1.412)","(BUB1, 0.371)","(TTK, -0.177)"]
[230,"focal adhesion formation (GO:0048041)",2,0.201,0.632,0.94559,"(SORBS1, 0.706)","(TESK2, 0.434)"]
[230,"aktPathway Second messenger PIP3 promotes cell survival by activating the anti-apoptotic kinase AKT.",19,0.201,0.632,1,"(NFKBIA, 1.035)","(NFKB1, 0.843)","(FOXO1A, 0.547)","(PPP2CA, 0.369)","(BAD, 0.124)","(GHR, 0.117)","(PDPK1, 0.116)","(FOXO3A, 0.114)","(GH1, 0.1)","(TNFSF6, 0.086)","(MLLT7, -0.014)","(YWHAH, -0.023)","(CHUK, -0.072)","(HSPCA, -0.072)","(PIK3R1, -0.086)","(RELA, -0.121)","(AKT1, -0.125)","(PIK3CA, -0.138)","(CASP9, -0.165)"]
[234,"hemopoiesis (GO:0030097)",4,0.202,0.635,1,"(NOTCH4, 1.229)","(IL10, 0.162)","(MLF1, 0.142)","(NOTCH2, -0.123)"]
[234,"ruffle organization and biogenesis (GO:0031529)",3,0.202,0.635,1,"(RAC1, 0.728)","(ARFIP2, 0.683)","(ARF6, -0.067)"]
[236,"negative regulation of transcription (GO:0016481)",15,0.203,0.635,0.78671,"(PER1, 0.824)","(WWP1, 0.757)","(RBM9, 0.687)","(TIMELESS, 0.19)","(GRLF1, 0.187)","(ZNF24, 0.173)","(RFX3, 0.071)","(PHB, 0.015)","(YAF2, -0.008)","(ZFHX1B, -0.033)","(SUMO1, -0.06)","(DEDD, -0.092)","(SIRT2, -0.102)","(KHDRBS1, -0.14)","(ZF, -0.2)"]
[236,"phagocytosis (GO:0006909)",4,0.203,0.635,0.97177,"(ADORA2A, 0.867)","(CD14, 0.607)","(CORO1C, -0.008)","(ADORA1, -0.156)"]
[238,"translational initiation (GO:0006413)",4,0.204,0.635,0.67271,"(EIF2AK3, 1.701)","(PAIP1, 0.38)","(EIF1AX, -0.074)","(EIF2B3, -0.217)"]
[238,"bbcellPathway Fas ligand expression by T cells induces apoptosis in Fas-expressing, inactive B cells.",8,0.204,0.635,0.86301,"(HLA-DRB1, 0.474)","(CD4, 0.473)","(CD28, 0.404)","(TNFRSF6, 0.19)","(TNFSF6, 0.18)","(TNFRSF5, 0.18)","(TNFSF5, 0.131)","(HLA-DRA, 0.02)"]
[240,"glycolysisPathway BioCarta",10,0.205,0.639,0,"(GPI, 0.901)","(ENO1, 0.533)","(PKLR, 0.412)","(PGAM1, 0.385)","(GAPD, 0.105)","(TPI1, 0.085)","(HK1, 0.061)","(PFKL, -0.067)","(ALDOB, -0.147)","(PGK1, -0.148)"]
[241,"protein complex assembly (GO:0006461)",74,0.206,0.639,0.72154,"(SLC7A11, 1.115)","(IL1RAP, 0.75)","(CHAF1B, 0.53)","(VAPA, 0.42)","(PTCH2, 0.372)","(PTK2B, 0.272)","(BCS1L, 0.245)","(MLL, 0.24)","(VAMP4, 0.224)","(VAMP3, 0.222)","(CAPZA1, 0.218)","(SLC7A7, 0.204)","(IKBKAP, 0.186)","(PPP2R1B, 0.16)","(CD74, 0.157)","(CHAF1A, 0.122)","(RIMS1, 0.116)","(TRAF2, 0.107)","(DAG1, 0.107)","(FANCA, 0.102)","(WAS, 0.1)","(PARD3, 0.07)","(MNAT1, 0.045)","(TCAP, 0.044)","(REPS2, 0.028)","(LAMC1, 0.026)","(PPARGC1A, 0.021)","(KPNA3, 0.004)","(EPRS, 0)","(WASPIP, 0)","(HFE, 0)","(TRAF1, 0)","(SLC7A9, 0)","(PPIH, 0)","(SLC9A3R2, 0)","(TUBGCP2, 0)","(CREBBP, 0)","(CLDN14, 0)","(SYK, 0)","(MDM2, 0)","(CD3D, 0)","(DARS, 0)","(PICALM, 0)","(SF3B3, 0)","(TAPBP, 0)","(MATN1, 0)","(LPXN, 0)","(VAPB, 0)","(APBA1, 0)","(MPP2, 0)","(CAPZA2, 0)","(APC, 0)","(IL2RG, 0)","(SLC7A8, 0)","(STK16, 0)","(VAMP8, 0)","(SH3BGR, 0)","(WASL, 0)","(DLG4, 0)","(WASF3, 0)","(KIFAP3, 0)","(TCEB2, 0)","(CD2AP, 0)","(SLC9A3R1, 0)","(FANCC, 0)","(RHAG, 0)","(PPP2R1A, 0)","(NFS1, 0)","(LIN7A, 0)","(IL2RB, 0)","(MDM4, 0)","(VIL1, -0.015)","(OCLN, -0.021)","(OXA1L, -0.087)"]
[241,"rarPathway BLACK",3,0.206,0.639,0.86552,"(RXRA, 1.214)","(RARA, 0.217)","(CDK7, -0.093)"]
[243,"negative regulation of caspase activity (GO:0001719)",4,0.207,0.639,1,"(BIRC7, 0.929)","(TNFRSF7, 0.712)","(TNFSF14, -0.025)","(AVEN, -0.078)"]
[244,"ST PAC1 RECEPTOR PATHWAY Signalling Transduction KE",8,0.208,0.64,0.81996,"(CAMP, 1.178)","(GAS, 0.792)","(DAG1, 0.25)","(ITPKA, -0.037)","(GNAQ, -0.076)","(ASAH1, -0.112)","(PACAP, -0.147)","(ITPKB, -0.164)"]
[245,"nerve ensheathment (GO:0008366)",3,0.211,0.647,0.93241,"(POU3F1, 0.982)","(PPARD, 0.426)","(MBP, -0.087)"]
[246,"Electron Transport Chain BioCarta",86,0.212,0.652,0.469,"(UCP2, 0.942)","(COX6A1, 0.479)","(ATP5I, 0.412)","(NDUFB3, 0.337)","(ATP5J2, 0.317)","(ATP5O, 0.256)","(NDUFB4, 0.255)","(SURF1, 0.233)","(ATP5D, 0.229)","(ATP5G2, 0.227)","(NDUFA2, 0.224)","(NDUFB1, 0.209)","(NDUFB7, 0.186)","(SDHB, 0.18)","(NDUFS2, 0.162)","(UQCR, 0.156)","(COX7A2, 0.139)","(COX7B, 0.137)","(COX5B, 0.132)","(COX7A1, 0.117)","(NDUFS7, 0.117)","(NDUFC1, 0.117)","(ATP5E, 0.113)","(POPDC2, 0.111)","(ATP5G3, 0.084)","(NDUFA8, 0.082)","(ATP5C1, 0.075)","(COX6A2, 0.067)","(NDUFS1, 0.058)","(NDUFAB1, 0.057)","(ATPIF1, 0.044)","(COX4I1, 0.037)","(NDUFS3, 0.035)","(UCP1, 0.034)","(QP-C, 0.03)","(NDUFA3, 0.029)","(ATP5J, 0.029)","(COX6B, 0.028)","(NDUFB5, 0.021)","(NDUFS5, 0.014)","(UCP3, 0.007)","(NDUFA4, 0.007)","(NDUFC2, 0)","(NDUFA10, 0)","(UQCRFS1, 0)","(UQCRC2, 0)","(NDUFB6, 0)","(COX15, 0)","(ATP5S, 0)","(COX5A, 0)","(NDUFA6, 0)","(ATP5B, 0)","(CYCS, 0)","(NDUFS8, 0)","(AFG3L2, 0)","(SDHD, 0)","(NDUFA5, 0)","(ATP5F1, 0)","(NDUFB2, 0)","(COX7A2L, 0)","(ATP5A1, 0)","(NDUFA7, 0)","(ZNF183, 0)","(SLC25A5, 0)","(UQCRH, 0)","(COX6C, 0)","(SLC25A6, 0)","(NDUFS4, 0)","(NDUFA9, 0)","(ATP5L, 0)","(NDUFS6, 0)","(COX7C, 0)","(NDUFV1, 0)","(TBDN100, 0)","(ATP5H, 0)","(ATP5G1, 0)","(SDHA, 0)","(NDUFV2, 0)","(SDHC, 0)","(HSPC051, 0)","(UQCRC1, 0)","(COX11, 0)","(SLC25A4, 0)","(UQCRB, -0.01)","(NDUFB8, -0.021)","(SLC25A14, -0.038)"]
[246,"cyanate catabolism (GO:0009440)",2,0.212,0.652,0.92808,"(TST, 0.696)","(MPST, 0.54)"]
[246,"INSULIN 2F DOWN Rome et al 2003",33,0.212,0.652,1,"(BCL10, 0.451)","(B1, 0.445)","(PCDH17, 0.44)","(C10orf10, 0.391)","(CLTB, 0.289)","(CNTN2, 0.281)","(MLL, 0.273)","(TOX, 0.25)","(TGM3, 0.224)","(BRD4, 0.184)","(CYP4A11, 0.159)","(MSH5, 0.157)","(ELA3A, 0.148)","(CDC16, 0.099)","(ALMS1, 0.088)","(TCL6, 0.07)","(KIAA1117, 0.067)","(MAD, 0.066)","(SERPINA1, 0.064)","(KIAA0746, 0.053)","(NIN, 0.048)","(PRKR, 0)","(CRYBA4, -0.003)","(MMP23B, -0.008)","(TGFB2, -0.02)","(FNBP3, -0.041)","(FBXL6, -0.055)","(PRKX, -0.065)","(SH2D3C, -0.071)","(FLJ10815, -0.089)","(TRAD, -0.105)","(C6orf4, -0.135)","(CPA1, -0.177)"]
[249,"excretion (GO:0007588)",33,0.213,0.656,0.62213,"(KCNJ1, 0.591)","(CLCNKB, 0.532)","(ATP6V1B1, 0.505)","(AQP1, 0.371)","(ADORA2B, 0.36)","(AQP6, 0.356)","(UNC13B, 0.336)","(NPHS2, 0.225)","(SCNN1G, 0.191)","(AQP3, 0.142)","(SCTR, 0.141)","(ADM, 0.094)","(NR3C2, 0.093)","(AVPR2, 0.065)","(AQP2, 0.06)","(SLC26A3, 0.059)","(CLCN5, 0.054)","(GUCA2B, 0.027)","(SCNN1B, 0.017)","(GRHPR, 0.017)","(TACR2, 0.007)","(CLDN16, 0)","(CLCNKA, -0.01)","(KCNK5, -0.015)","(AQP5, -0.015)","(SCNN1A, -0.023)","(AQP4, -0.025)","(NFAT5, -0.029)","(NPHS1, -0.03)","(AQP9, -0.032)","(AQP7, -0.107)","(NPHP1, -0.112)","(TTC10, -0.14)"]
[249,"galactose metabolism (GO:0006012)",4,0.213,0.656,0.83362,"(GALK1, 1.492)","(GALT, 0.745)","(SLC35A2, -0.246)","(CHST1, -0.248)"]
[249,"cell adhesion receptor activity OBSOLETE. Combining with cell adhesion molecules to initiate a change in cell activity.",34,0.213,0.656,0.8922,"(ITGA6, 1.104)","(FLRT3, 0.782)","(ITGAV, 0.429)","(ITGB5, 0.398)","(SELP, 0.231)","(ITGB2, 0.19)","(ITGA7, 0.159)","(ITGAL, 0.124)","(DAG1, 0.121)","(ITGBL1, 0.11)","(ITGAX, 0.107)","(ITGA2B, 0.083)","(ITGA2, 0.08)","(ITGA10, 0.076)","(ITGB8, 0.06)","(ITGA4, 0.055)","(CDA08, 0.041)","(ITGAM, 0.031)","(TNC, 0.021)","(FLJ10539, 0.016)","(ITGB1, 0.014)","(ITGA8, 0.012)","(MDS028, 0.011)","(ITGB4, 0)","(ITGA9, 0)","(TNFAIP6, -0.007)","(ITGAE, -0.022)","(ITGA3, -0.041)","(ITGB3, -0.06)","(CRTAC1, -0.066)","(ITGA5, -0.076)","(ITGB6, -0.102)","(MADCAM1, -0.117)","(ITGB7, -0.14)"]
[249,"protein import into nucleus, translocation (GO:0000060)",4,0.213,0.656,0.93747,"(GLI3, 1.503)","(TNPO1, 0.3)","(KPNB1, -0.008)","(ARNT, -0.282)"]
[253,"hbxPathway BioCarta",8,0.214,0.658,0.94968,"(PTK2B, 0.853)","(CREB1, 0.613)","(HBXIP, 0.481)","(SRC, 0.007)","(GRB2, 0.003)","(HRAS, -0.011)","(SOS1, -0.046)","(SHC1, -0.077)"]
[254,"bile acid biosynthesis (GO:0006699)",3,0.215,0.663,0.88952,"(CYP39A1, 1.61)","(CYP7B1, 0.013)","(CYP7A1, -0.324)"]
[255,"ldlPathway BioCarta",6,0.217,0.667,0.80718,"(LPL, 0.747)","(CSF1, 0.478)","(LDLR, 0.328)","(IL6, 0.27)","(ACAT1, -0.084)","(CCL2, -0.2)"]
[256,"centrosome cycle (GO:0007098)",2,0.22,0.672,0.84355,"(NPM1, 1.627)","(CETN3, -0.254)"]
[256,"cAMP biosynthesis (GO:0006171)",2,0.22,0.672,0.94253,"(ADORA2A, 1.222)","(ADM, 0.123)"]
[256,"NFKB REDUCED Hinata et al 2003",21,0.22,0.672,1,"(CEACAM6, 1.207)","(UPK1B, 1.099)","(SULT2B1, 0.941)","(C4BPA, 0.216)","(DAPK1, 0.119)","(ZNF185, 0.113)","(HYAL1, 0.039)","(RAI3, 0.035)","(THBS1, 0.034)","(DSG3, 0.007)","(INA, 0)","(RUNX1, -0.003)","(RGS2, -0.038)","(PPL, -0.038)","(PTHLH, -0.048)","(DUSP4, -0.09)","(SCEL, -0.09)","(KIAA0350, -0.106)","(RIMS2, -0.126)","(KLK6, -0.128)","(KLK7, -0.148)"]
[259,"defense response to Gram-positive bacteria (GO:0050830)",2,0.221,0.672,0.9038,"(PGLYRP1, 1.537)","(PGLYRP4, -0.155)"]
[260,"regulation of cell volume (GO:0006884)",2,0.222,0.672,0.89974,"(SLC12A4, 1.437)","(TRPV4, -0.228)"]
[260,"circadian rhythm (GO:0007623)",9,0.222,0.672,0.9551,"(ARNTL, 0.591)","(AANAT, 0.496)","(PER2, 0.424)","(CLOCK, 0.415)","(TIMELESS, 0.234)","(NPY2R, 0.23)","(HTR7, -0.021)","(EGR3, -0.116)","(MTNR1A, -0.152)"]
[260,"soddPathway BioCarta",10,0.222,0.672,1,"(TRADD, 1.051)","(BIRC3, 0.541)","(TNFRSF1A, 0.388)","(TRAF2, 0.364)","(CASP8, -0.012)","(RIPK1, -0.019)","(BAG4, -0.053)","(TNFRSF1B, -0.086)","(TNF, -0.158)","(FADD, -0.181)"]
[263,"actin cytoskeleton organization and biogenesis (GO:0030036)",29,0.223,0.672,0.70471,"(AVIL, 0.661)","(CFL1, 0.606)","(CRK, 0.47)","(ADRA2A, 0.441)","(FLNB, 0.305)","(PACSIN2, 0.267)","(KLHL5, 0.219)","(ARFIP2, 0.166)","(FLNA, 0.154)","(ARPC5, 0.135)","(TESK2, 0.125)","(MTSS1, 0.121)","(FGD2, 0.091)","(ROCK1, 0.09)","(PSCD2, 0.08)","(PDPK1, 0.069)","(FGD6, 0.038)","(RHOA, 0.037)","(DOCK2, 0)","(MRAS, -0.01)","(ELMO1, -0.013)","(PLEK2, -0.024)","(PRKG1, -0.044)","(FGD1, -0.045)","(WASF2, -0.075)","(LIMK1, -0.077)","(ARHGDIB, -0.101)","(FSCN1, -0.104)","(KLHL4, -0.135)"]
[263,"phospholipid metabolism (GO:0006644)",13,0.223,0.672,0.72729,"(PLA2G6, 1.156)","(PLCG2, 0.871)","(PLA2G5, 0.193)","(PLD1, 0.15)","(GPX4, 0.13)","(PLA2G2D, 0.046)","(CLC, 0.039)","(PLA2G3, 0.008)","(PLA2G2E, -0.006)","(PLCD1, -0.03)","(PLCB2, -0.049)","(PLAA, -0.154)","(LGALS13, -0.189)"]
[263,"negative regulation of B cell differentiation (GO:0045578)",2,0.223,0.672,0.94068,"(INHA, 1.212)","(INHBA, -0.069)"]
[266,"MAP00710 Carbon fixation GenMAPP",16,0.225,0.673,1,"(ALDOA, 1.56)","(PKLR, 0.334)","(ALDOC, 0.322)","(GPT, 0.229)","(FBP2, 0.206)","(GOT2, 0.184)","(MDH1, 0.102)","(TPI1, 0.069)","(FBP1, 0.039)","(PGK1, -0.057)","(GOT1, -0.08)","(PKM2, -0.112)","(ALDOB, -0.122)","(ME3, -0.131)","(ME1, -0.183)","(MDH2, -0.186)"]
[267,"cholesterol catabolism (GO:0006707)",2,0.226,0.673,0.80394,"(CYP46A1, 1.252)","(CEL, -0.015)"]
[267,"NFKB INDUCED Hinata et al 2003",109,0.226,0.673,1,"(ABCC1, 0.959)","(WNT5A, 0.589)","(KRT14, 0.541)","(SOD1, 0.459)","(RARRES1, 0.419)","(NFKB1, 0.407)","(AP2B1, 0.343)","(TIAM1, 0.246)","(NPR1, 0.24)","(ARHE, 0.227)","(IL1A, 0.226)","(SERPINB2, 0.224)","(SERPINE1, 0.199)","(RAC2, 0.192)","(LITAF, 0.185)","(GABBR1, 0.185)","(WFDC2, 0.181)","(PLAT, 0.167)","(CCL20, 0.151)","(SAA1, 0.124)","(IER3, 0.117)","(KRT10, 0.096)","(MMP1, 0.095)","(SELE, 0.092)","(RABEP1, 0.074)","(ERCC1, 0.049)","(SPRR1B, 0.045)","(RAC1, 0.032)","(PMSCL1, 0.024)","(CDH3, 0.016)","(TNIP1, 0.002)","(MAP1B, 0)","(RELA, 0)","(CTSE, 0)","(CCL2, 0)","(CXCL5, 0)","(CFLAR, 0)","(TNF, 0)","(PLAU, 0)","(IL1B, 0)","(SOD2, 0)","(FGF5, 0)","(MSC, 0)","(STAT5A, 0)","(IRF1, 0)","(ARHGDIB, 0)","(GCH1, 0)","(GADD45A, 0)","(CXCL10, 0)","(IFNAR2, 0)","(GTF2H4, 0)","(IL7R, 0)","(CDH2, 0)","(BTN3A3, 0)","(CXCL11, 0)","(GPR37, 0)","(SLC7A2, 0)","(IL8, 0)","(MAPK9, 0)","(PTX3, 0)","(ICAM1, 0)","(CCNB1, 0)","(TAP1, 0)","(IL6, 0)","(CXCL6, 0)","(ESM1, 0)","(ADAMTS3, 0)","(FN1, 0)","(MMP9, 0)","(EDN1, 0)","(CYP27B1, 0)","(ITGB6, 0)","(MYBL1, 0)","(SPTBN1, 0)","(EFNA1, 0)","(ETS1, 0)","(TNC, 0)","(BCL2A1, 0)","(XPC, 0)","(OLR1, 0)","(TNFAIP2, 0)","(IL1RN, 0)","(PNRC1, 0)","(GBP1, 0)","(RELB, 0)","(SEC24A, 0)","(MMP14, 0)","(NK4, 0)","(CXCL3, 0)","(BMP2, 0)","(IL15, 0)","(CSF2, 0)","(FGF2, 0)","(TNFAIP6, 0)","(CD83, 0)","(KIAA0608, 0)","(HGFAC, 0)","(ARF6, 0)","(NFKB2, 0)","(UTX, 0)","(KRT7, 0)","(RPA2, 0)","(MAP2K3, 0)","(CCL5, 0)","(CD9, 0)","(TAF15, 0)","(CDKN1A, 0)","(KRT6B, -0.004)","(CXCL2, -0.007)"]
[267,"ST G alpha 5 Pathway Signalling Transduction KE",14,0.226,0.673,1,"(CAMP, 0.911)","(GAS, 0.611)","(CREB3, 0.486)","(CREB1, 0.463)","(SNX13, 0.135)","(BRAF, 0.128)","(BF, 0.066)","(RAF1, 0.043)","(SRC, 0)","(MAPK1, -0.019)","(ASAH1, -0.083)","(TERF2IP, -0.095)","(CREB5, -0.103)","(BFAR, -0.158)"]
[270,"MAP00650 Butanoate metabolism GenMAPP",20,0.227,0.673,0.91218,"(BDH, 0.569)","(HMGCS2, 0.561)","(ALDH2, 0.542)","(GAD1, 0.513)","(PDHB, 0.425)","(HADHA, 0.292)","(HMGCS1, 0.291)","(ABAT, 0.28)","(PDHA2, 0.104)","(ECHS1, 0.06)","(HMGCL, 0)","(PDHA1, -0.015)","(ACAT1, -0.015)","(ALDH3A2, -0.042)","(ALDH1A1, -0.052)","(GAD2, -0.096)","(ACADS, -0.122)","(ALDH1B1, -0.13)","(ALDH5A1, -0.142)","(EHHADH, -0.184)"]
[271,"cell aging (GO:0007569)",3,0.232,0.675,0.73526,"(NPM1, 1.387)","(TP53, 0.025)","(LIMS1, 0.014)"]
[271,"glutamate decarboxylation to succinate (GO:0006540)",2,0.232,0.675,0.87897,"(GAD1, 1.372)","(GAD2, -0.193)"]
[271,"regulation of cell adhesion (GO:0030155)",3,0.232,0.675,0.92572,"(IL18, 0.959)","(PPP2R1B, 0.564)","(IL8, 0.024)"]
[274,"nfkbPathway BioCarta",23,0.233,0.675,0.9511,"(NFKBIA, 1.006)","(NFKB1, 0.794)","(TRADD, 0.714)","(IL1A, 0.511)","(TNFAIP3, 0.289)","(IRAK1, 0.283)","(TNFRSF1A, 0.262)","(TLR4, 0.204)","(IL1R1, 0.08)","(MAP3K7IP1, 0.071)","(TRAF6, 0.043)","(IKBKG, -0.007)","(MAP3K7, -0.007)","(RIPK1, -0.04)","(CHUK, -0.043)","(MAP3K1, -0.044)","(TNF, -0.05)","(TNFRSF1B, -0.101)","(MYD88, -0.125)","(FADD, -0.132)","(IKBKB, -0.133)","(RELA, -0.171)","(MAP3K14, -0.2)"]
[275,"sensory perception of sound (GO:0007605)",29,0.234,0.675,0.73168,"(JAG2, 0.979)","(ATP6V1B1, 0.528)","(TIMM9, 0.47)","(DFNA5, 0.401)","(DIAPH1, 0.34)","(TIMM13, 0.3)","(OTOF, 0.298)","(EYA1, 0.236)","(ZNF354A, 0.224)","(KCNQ1, 0.214)","(ALDH7A1, 0.119)","(EML2, 0.107)","(POU3F4, 0.082)","(KCNQ4, 0.042)","(COCH, 0.013)","(TBL1X, 0.01)","(SLC26A4, 0.003)","(KCNE1, -0.025)","(COL4A3, -0.028)","(LARGE, -0.033)","(PAX3, -0.061)","(OTOR, -0.078)","(MYO15A, -0.09)","(TECTA, -0.092)","(MYO7A, -0.096)","(TIMM8B, -0.099)","(POU4F3, -0.113)","(MYO6, -0.162)","(WDR1, -0.184)"]
[275,"neuron differentiation (GO:0030182)",4,0.234,0.675,0.85426,"(RTN1, 0.442)","(IL6, 0.36)","(LMX1B, 0.289)","(BTG4, 0.254)"]
[275,"hemoglobin biosynthesis (GO:0042541)",2,0.234,0.675,0.94068,"(INHA, 1.187)","(INHBA, -0.065)"]
[278,"cd40Pathway The CD40 receptor is a TNF-type receptor that regulates immunoglobulin expression in B cells and moderates T cell activation via T-cell expression of its ligand.",15,0.235,0.675,0.72103,"(NFKBIA, 1.141)","(NFKB1, 0.888)","(TNFAIP3, 0.342)","(IKBKAP, 0.255)","(TRAF3, 0.225)","(TNFRSF5, 0.121)","(TNFSF5, 0.118)","(TRAF6, 0.061)","(CHUK, 0.021)","(DUSP1, -0.008)","(MAP3K14, -0.054)","(MAP3K1, -0.093)","(IKBKG, -0.112)","(RELA, -0.16)","(IKBKB, -0.182)"]
[279,"cell motility (GO:0006928)",95,0.236,0.675,0.79092,"(TXN, 0.55)","(CTGF, 0.545)","(KAL1, 0.502)","(LTB4R, 0.369)","(PALM, 0.361)","(ARPC1B, 0.292)","(SPINT2, 0.289)","(ADRA2A, 0.278)","(CRK, 0.26)","(SERPINB5, 0.229)","(THBS3, 0.219)","(MKLN1, 0.209)","(PYY, 0.209)","(ARPC3, 0.209)","(CAPZA1, 0.208)","(ANXA1, 0.206)","(SERPINI2, 0.191)","(CCL4, 0.167)","(SEMA3E, 0.138)","(SPOCK, 0.125)","(VASP, 0.124)","(CCR6, 0.11)","(ALOX12, 0.106)","(VNN2, 0.103)","(VNN1, 0.092)","(ARFIP2, 0.088)","(MAPK14, 0.073)","(PAFAH1B1, 0.057)","(NTF3, 0.044)","(CCL3, 0.031)","(MST1R, 0.028)","(CD9, 0.025)","(IGF1, 0.021)","(NEO1, 0.021)","(KATNB1, 0.013)","(FLNA, 0.007)","(PAK4, 0)","(FPRL1, 0)","(ARPC2, 0)","(MYLIP, 0)","(ARPC5, 0)","(ARF6, 0)","(CRKL, 0)","(MARCKS, 0)","(NOS3, 0)","(ITGAL, 0)","(CD97, 0)","(PXN, 0)","(BLR1, 0)","(C3AR1, 0)","(THBS1, 0)","(MAP2K1, 0)","(GNA13, 0)","(JAK2, 0)","(CXCR3, 0)","(HGFAC, 0)","(ACTR3, 0)","(PTGS2, 0)","(ENPP2, 0)","(ELMO1, 0)","(MAPK8, 0)","(AAMP, 0)","(LIMK1, 0)","(F11R, 0)","(CAPZA2, 0)","(SELL, 0)","(PECAM1, 0)","(LSP1, 0)","(HRAS, 0)","(STAT3, 0)","(AMFR, 0)","(DNALI1, 0)","(WASL, 0)","(FPR1, 0)","(CSPG3, 0)","(F2R, 0)","(HMMR, 0)","(FPRL2, 0)","(IL8, 0)","(NPY, 0)","(DNAH9, 0)","(YARS, 0)","(IFNG, 0)","(CORO1A, 0)","(TNFRSF12A, 0)","(AKAP3, 0)","(NTN1, 0)","(IL8RB, 0)","(CCL5, 0)","(IL13, 0)","(ACTN4, 0)","(WASF1, 0)","(OR1D2, 0)","(MMP12, -0.016)","(CXCL10, -0.028)"]
[280,"cholesterol biosynthesis (GO:0006695)",3,0.237,0.675,0.73396,"(NSDHL, 1.554)","(DHCR7, -0.086)","(FDPS, -0.168)"]
[281,"intracellular protein transport (GO:0006886)",28,0.238,0.675,0.30342,"(KLHL2, 0.634)","(NPM1, 0.459)","(AP3B1, 0.446)","(KDELR2, 0.43)","(TAP2, 0.383)","(PACSIN2, 0.337)","(CD74, 0.268)","(BRDG1, 0.219)","(AP1G1, 0.17)","(GGA1, 0.147)","(AP1S1, 0.116)","(TLK1, 0.089)","(SEC23IP, 0.047)","(SGNE1, 0.031)","(COG2, 0.023)","(PPGB, 0.008)","(APBA1, 0.007)","(NPC1, 0.005)","(RPGR, -0.005)","(ARCN1, -0.007)","(VPS45A, -0.023)","(KDELR1, -0.034)","(A2M, -0.072)","(C12orf8, -0.074)","(TRPC4AP, -0.081)","(LGTN, -0.102)","(APPBP2, -0.119)","(AP3D1, -0.131)"]
[281,"MAP00052 Galactose metabolism GenMAPP",23,0.238,0.675,0.9246,"(AKR1B1, 1.412)","(GALK1, 0.706)","(GALT, 0.424)","(GALE, 0.381)","(UGP2, 0.195)","(MGAM, 0.193)","(PFKM, 0.121)","(B4GALT2, 0.044)","(HK1, 0.023)","(HK3, 0.001)","(B4GALT1, 0)","(PFKP, -0.004)","(GALK2, -0.006)","(GLB1, -0.046)","(HK2, -0.081)","(G6PC, -0.086)","(LCT, -0.087)","(GLA, -0.096)","(GAA, -0.111)","(LALBA, -0.129)","(PFKL, -0.129)","(GCK, -0.131)","(PGM1, -0.197)"]
[283,"SIG CD40PATHWAYMAP SignallingAlliance",34,0.239,0.675,0.25316,"(NFKBIA, 0.829)","(NFKB1, 0.692)","(TRAF5, 0.477)","(MAPK13, 0.4)","(MAPK11, 0.396)","(NFKBIL1, 0.242)","(GORASP1, 0.22)","(TRAF3, 0.171)","(MAPK14, 0.146)","(NFKB2, 0.132)","(TRAF2, 0.111)","(MAPK8IP1, 0.104)","(TNFRSF5, 0.092)","(MAPK3, 0.067)","(MAPK8IP2, 0.054)","(DUSP1, 0)","(MAPKAPK5, -0.008)","(NFKBIL2, -0.009)","(NFKBIB, -0.011)","(MAPK8, -0.012)","(TRAF6, -0.014)","(SYT1, -0.014)","(IKBKG, -0.015)","(MAP2K7, -0.018)","(MAPK1, -0.02)","(MAPK9, -0.049)","(MAPK12, -0.052)","(MAPK8IP3, -0.064)","(MAP2K4, -0.079)","(PIK3R1, -0.089)","(MAPK10, -0.093)","(PIK3CD, -0.124)","(NFKBIE, -0.125)","(PIK3CA, -0.181)"]
[284,"activation of NF-kappaB transcription factor (GO:0051092)",2,0.241,0.675,0.88197,"(NPM1, 1.652)","(PRDX3, -0.286)"]
[285,"AR ORTHOS MAPPED TO U133 VIA NETAFFX na",45,0.242,0.675,0.51818,"(AGR2, 1.004)","(ERP70, 0.644)","(FKBP11, 0.556)","(SC4MOL, 0.328)","(FDFT1, 0.293)","(ISYNA1, 0.281)","(GFRA1, 0.24)","(MAN1A1, 0.224)","(CYB561, 0.181)","(KCNK1, 0.164)","(ARAF1, 0.1)","(GPC1, 0.095)","(NCF2, 0.091)","(RAMP3, 0.088)","(GLUL, 0.076)","(KLRB1, 0.054)","(NUCB2, 0.041)","(GJB3, 0.031)","(STMN1, 0.025)","(RRM1, 0.021)","(ADCY8, 0.012)","(ADAM7, 0)","(GSTM1, 0)","(FKBP5, 0)","(EBP, 0)","(KCNK7, 0)","(ACE, 0)","(AGPAT3, 0)","(TCF7, 0)","(INDO, -0.004)","(ISG20, -0.019)","(PEMT, -0.02)","(GPX5, -0.021)","(CA4, -0.022)","(ENPP1, -0.024)","(ADRA2C, -0.029)","(FDPS, -0.034)","(ALPL, -0.068)","(MYOM2, -0.072)","(GLDC, -0.08)","(TPMT, -0.091)","(PTPRO, -0.095)","(BTG3, -0.096)","(KIAA0251, -0.125)","(CA2, -0.15)"]
[285,"rarrxrPathway BioCarta",15,0.242,0.675,0.97385,"(NCOR2, 1.383)","(RXRA, 0.615)","(NCOA3, 0.187)","(GTF2E1, 0.172)","(ERCC3, 0.151)","(GTF2B, 0.119)","(HDAC3, 0.081)","(RARA, 0.075)","(POLR2A, 0.018)","(TBP, 0.007)","(NCOA2, -0.031)","(GTF2F1, -0.078)","(NCOA1, -0.09)","(PCAF, -0.137)","(GTF2A1, -0.167)"]
[287,"adenylate cyclase activation (GO:0007190)",17,0.243,0.675,0.55263,"(CAP1, 0.748)","(GHRHR, 0.503)","(ADORA2A, 0.472)","(ADORA2B, 0.459)","(P2RY11, 0.444)","(GLP1R, 0.24)","(ADRB2, 0.178)","(AVPR2, 0.015)","(CRHR1, -0.014)","(EDNRA, -0.038)","(ADCYAP1, -0.052)","(ADORA3, -0.071)","(CALCR, -0.103)","(CALCA, -0.11)","(CAP2, -0.114)","(GIPR, -0.143)","(ADRB1, -0.196)"]
[287,"vitamin metabolism (GO:0006766)",2,0.243,0.675,0.77616,"(RXRA, 1.372)","(FDX1, -0.238)"]
[287,"positive regulation of T cell proliferation (GO:0042102)",6,0.243,0.675,0.86438,"(CD3E, 0.537)","(CD28, 0.408)","(NCK1, 0.228)","(SPP1, 0.212)","(IL21, 0.07)","(NCK2, 0.03)"]
[287,"dephosphorylation (GO:0016311)",2,0.243,0.675,0.90281,"(THTPA, 1.107)","(PNKP, 0.052)"]
[287,"BRCA UP Welcsh et al 2002",40,0.243,0.675,1,"(TFPI2, 0.633)","(P2RX1, 0.61)","(IDH1, 0.375)","(VAMP3, 0.338)","(CCNG2, 0.277)","(ADD1, 0.268)","(LAMA3, 0.247)","(RRM2, 0.245)","(CLTB, 0.225)","(IL16, 0.22)","(KCNK1, 0.217)","(MGAT2, 0.205)","(CITED2, 0.201)","(GALNT3, 0.134)","(EXTL2, 0.125)","(H1F0, 0.112)","(PPP1R1A, 0.092)","(PBP, 0.091)","(SEPP1, 0.088)","(SERPINB1, 0.066)","(JAK1, 0.038)","(APP, 0.021)","(ZNF148, 0.02)","(STC1, 0)","(ENPP2, 0)","(SEC23A, -0.008)","(TSNAX, -0.017)","(MAP2K1, -0.021)","(STAT1, -0.028)","(KIF2, -0.029)","(FSTL1, -0.041)","(RDX, -0.046)","(CALD1, -0.048)","(WRB, -0.066)","(NFYC, -0.092)","(HTATIP, -0.095)","(ID4, -0.1)","(TITF1, -0.104)","(LIMS1, -0.106)","(LIPA, -0.111)"]
[292,"stemPathway BioCarta",15,0.244,0.676,0.5112,"(IL9, 0.748)","(CSF3, 0.673)","(CD4, 0.361)","(CSF1, 0.329)","(CSF2, 0.133)","(IL6, 0.114)","(IL5, 0.078)","(IL7, 0.051)","(IL8, -0.012)","(IL3, -0.028)","(EPO, -0.03)","(IL4, -0.069)","(CD8A, -0.077)","(IL2, -0.121)","(IL11, -0.179)"]
[292,"tyrosine catabolism (GO:0006572)",3,0.244,0.676,0.93037,"(HGD, 1.015)","(FAH, 0.39)","(HPD, -0.193)"]
[294,"cell death Activation or halting of cellular processes so that vital functions markedly cease, culminating in cell death.",13,0.245,0.681,1,"(CLUL1, 0.996)","(EMP3, 0.403)","(FOSL2, 0.324)","(CLU, 0.266)","(IL17, 0.247)","(APP, 0.192)","(EIF4G2, 0.052)","(EMP1, 0.05)","(EMP2, 0.045)","(OPTN, 0.04)","(EVI1, 0.033)","(RRAGA, -0.006)","(PTGER3, -0.037)"]
[295,"MAP kinase activity GenMAPP",8,0.246,0.681,0.88288,"(MAPK13, 0.853)","(MAPK11, 0.597)","(MAPK14, 0.377)","(MAPK7, 0.351)","(MAPK3, 0.03)","(MAPK1, -0.048)","(MAPK12, -0.097)","(MAPK4, -0.108)"]
[295,"mRNA cleavage (GO:0006379)",3,0.246,0.681,0.99523,"(CPSF1, 0.914)","(CSTF1, 0.392)","(CSTF2, 0.179)"]
[297,"tidPathway BioCarta",19,0.247,0.681,0.5839,"(NFKBIA, 1.09)","(NFKB1, 0.891)","(HSPA1A, 0.528)","(RB1, 0.327)","(TIP-1, 0.275)","(TNFRSF1A, 0.231)","(IFNGR1, 0.167)","(IFNGR2, 0.011)","(DNAJA3, 0.008)","(TP53, -0.008)","(TNF, -0.017)","(USH1C, -0.023)","(IFNG, -0.04)","(LIN7A, -0.054)","(TNFRSF1B, -0.075)","(WT1, -0.142)","(JAK2, -0.175)","(IKBKB, -0.178)","(RELA, -0.2)"]
[298,"cdmacPathway Cadmium 2+ promotes cell proliferation in cultured macrophages by entering the cell via calcium channels and activating the MAP kinase pathway.",16,0.248,0.681,0.71862,"(NFKBIA, 1.147)","(NFKB1, 0.967)","(JUN, 0.458)","(RAF1, 0.188)","(MYC, 0.148)","(FOS, 0.142)","(MAPK3, 0.129)","(CUZD1, 0.063)","(MAPK1, 0.053)","(HRAS, -0.021)","(TNF, -0.042)","(PRKCB1, -0.054)","(PLCB1, -0.056)","(MAP2K1, -0.082)","(PRKCA, -0.154)","(RELA, -0.187)"]
[299,"diuresis (GO:0030146)",3,0.249,0.681,0.85654,"(NPR1, 1.205)","(NPPB, 0.127)","(KNG1, -0.04)"]
[299,"homeostasis (GO:0042592)",2,0.249,0.681,0.97262,"(HIF1A, 1.418)","(EP300, -0.006)"]
[301,"ST B Cell Antigen Receptor Signalling Transduction KE",39,0.25,0.681,0.32877,"(NFKBIA, 0.824)","(VAV1, 0.697)","(NFKB1, 0.619)","(PLCG2, 0.515)","(AKT2, 0.497)","(CSK, 0.343)","(BTK, 0.187)","(NFKBIL1, 0.162)","(RAF1, 0.132)","(DAG1, 0.114)","(SOS2, 0.11)","(PI3, 0.089)","(MAP2K2, 0.082)","(NFKB2, 0.079)","(LYN, 0.029)","(SOS1, 0.024)","(NFKBIB, 0.021)","(BAD, 0.009)","(MAPK1, 0)","(PIK3R1, 0)","(EPHB2, 0)","(NFAT5, -0.003)","(ITPKA, -0.008)","(PPP1R13B, -0.014)","(SHC1, -0.019)","(AKT3, -0.051)","(PIK3CA, -0.053)","(ITPKB, -0.069)","(GRB2, -0.074)","(MAP2K1, -0.076)","(CD19, -0.091)","(NFKBIL2, -0.092)","(SYK, -0.1)","(AKT1, -0.114)","(BCR, -0.126)","(BLNK, -0.135)","(SERPINA4, -0.154)","(PIK3CD, -0.193)","(NFKBIE, -0.209)"]
[302,"actin filament organization (GO:0007015)",6,0.251,0.684,0.7605,"(EVL, 1.033)","(SPTA1, 0.49)","(PLA2G1B, 0.312)","(RND1, -0.025)","(DBN1, -0.077)","(RHOF, -0.089)"]
[302,"negative regulation of interferon-gamma biosynthesis (GO:0045077)",3,0.251,0.684,0.93785,"(INHA, 1.191)","(IL10, 0.282)","(INHBA, -0.064)"]
[302,"B cell differentiation (GO:0030183)",6,0.251,0.684,1,"(HDAC5, 1.036)","(HDAC9, 0.374)","(IL6, 0.223)","(HDAC4, 0.184)","(HDAC7A, -0.138)","(IL4, -0.158)"]
[305,"dendrite morphogenesis (GO:0016358)",2,0.253,0.689,0.97926,"(LST1, 0.729)","(TRAPPC4, 0.377)"]
[305,"glycogen metabolism (GO:0005977)",4,0.253,0.689,1,"(EPM2A, 0.983)","(GSK3B, 0.356)","(PYGM, 0.071)","(G6PC, -0.008)"]
[307,"double-strand break repair (GO:0006302)",8,0.254,0.693,0.82388,"(CIB1, 0.806)","(RAD21, 0.737)","(FEN1, 0.151)","(RAD50, 0.094)","(HTATIP, 0.067)","(PRKDC, 0.024)","(RAD52, -0.046)","(XRCC4, -0.143)"]
[307,"lipid transport (GO:0006869)",7,0.254,0.693,0.83382,"(CHKA, 1.35)","(SLCO2A1, 0.928)","(PSAP, 0.225)","(APOE, -0.048)","(ABCG1, -0.114)","(APOF, -0.233)","(APOA4, -0.276)"]
[307,"KET Manually Curated",7,0.254,0.693,0.86993,"(HMGCS2, 0.943)","(BDH, 0.881)","(HMGCL, 0.089)","(BCKDHB, 0.06)","(ACAT1, -0.054)","(BCKDHA, -0.063)","(LYPLA2, -0.082)"]
[307,"regulation of nitric-oxide synthase activity (GO:0050999)",2,0.254,0.693,1,"(NOS1AP, 0.006)","(EGFR, 0.001)"]
[311,"histone methylation (GO:0016571)",3,0.255,0.695,0.93135,"(CARM1, 0.838)","(NSD1, 0.65)","(EHMT1, -0.326)"]
[311,"negative regulation of phosphorylation (GO:0042326)",2,0.255,0.695,0.94068,"(INHA, 1.259)","(INHBA, -0.075)"]
[311,"il4Pathway BioCarta",11,0.255,0.695,1,"(IL4R, 1.502)","(RPS6KB1, 0.944)","(JAK1, 0.099)","(IRS1, 0.071)","(GRB2, -0.024)","(STAT6, -0.063)","(SHC1, -0.073)","(JAK3, -0.086)","(IL4, -0.095)","(AKT1, -0.108)","(IL2RG, -0.21)"]
[314,"neuropeptide signaling pathway (GO:0007218)",6,0.257,0.698,1,"(ECEL1, 0.98)","(AGRP, 0.535)","(NPFF, 0.415)","(GALR1, 0.013)","(HCRTR2, -0.102)","(HCRTR1, -0.127)"]
[314,"pyruvate metabolism (GO:0006090)",2,0.257,0.698,1,"(ME2, 1.352)","(ME3, -0.199)"]
[316,"fbw7Pathway Cyclin E interacts with cell cycle checkpoint kinase cdk2 to allow transcription of genes required for S phase, including transcription of additional cyclin E.",9,0.258,0.699,0.90349,"(SKP1A, 0.701)","(RB1, 0.494)","(CCNE1, 0.405)","(CUL1, 0.301)","(E2F1, 0.282)","(CDC34, -0.079)","(CDK2, -0.087)","(FBXW7, -0.171)","(TFDP1, -0.197)"]
[316,"ANTI CD44 UP Hogerkorp et al 2003",24,0.258,0.699,1,"(MITF, 0.612)","(AQP1, 0.455)","(IL1A, 0.45)","(MLLT3, 0.446)","(PDE6A, 0.321)","(CDKL5, 0.258)","(SOX5, 0.251)","(MAPK14, 0.179)","(ADRB2, 0.13)","(STX1A, 0.127)","(SH3BP2, 0.123)","(NBL1, 0.111)","(PYGL, 0.106)","(C18B11, 0.103)","(RGS3, 0.084)","(PLG, 0.073)","(GCNT2, 0.022)","(ECGF1, 0)","(AFAP, -0.048)","(ALB, -0.078)","(SERPINC1, -0.08)","(PIGA, -0.102)","(IF, -0.121)","(ATP1A2, -0.13)"]
[318,"negative regulation of striated muscle development (GO:0045843)",5,0.259,0.701,0.84933,"(HDAC5, 1.08)","(HDAC9, 0.361)","(HDAC4, 0.19)","(SIRT2, -0.038)","(HDAC7A, -0.106)"]
[319,"RNA catabolism (GO:0006401)",11,0.261,0.707,0.58835,"(ANG, 1.021)","(PPP1R8, 0.452)","(RNASE2, 0.398)","(HNRPD, 0.243)","(ELAVL1, 0.143)","(RNASEH2A, 0.059)","(ISG20, -0.008)","(RNASET2, -0.032)","(RNASEH1, -0.066)","(PABPC4, -0.085)","(RNASE6, -0.089)"]
[319,"GO ROS FO",28,0.261,0.707,0.91387,"(SOD1, 0.871)","(CCS, 0.607)","(FOXM1, 0.397)","(LTC4S, 0.382)","(NCF1, 0.312)","(SCARA3, 0.222)","(RPS6KA5, 0.202)","(PRDX2, 0.132)","(L3MBTL, 0.096)","(SEPP1, 0.095)","(MSRA, 0.087)","(NCF2, 0.062)","(DUSP1, 0.031)","(ATOX1, 0.03)","(MTL5, 0.028)","(CYBA, 0.014)","(GPX3, 0)","(NUDT1, 0)","(STK25, -0.005)","(MPO, -0.015)","(SGK2, -0.025)","(AOX1, -0.043)","(OSR1, -0.051)","(GSS, -0.063)","(CDT6, -0.094)","(SOD2, -0.107)","(PDLIM1, -0.119)","(CCL5, -0.153)"]
[321,"ST Gaq Pathway Signalling Transduction KE",28,0.264,0.712,0.71688,"(NFKBIA, 0.95)","(NFKB1, 0.76)","(AKT2, 0.544)","(ADRBK1, 0.294)","(PIK3CB, 0.276)","(NFKBIL1, 0.243)","(NFKB2, 0.155)","(DAG1, 0.134)","(PHKA2, 0.128)","(PLD1, 0.107)","(VN1R1, 0.059)","(BF, 0.034)","(ITPR3, 0.027)","(NFKBIB, 0.022)","(ITPR1, 0.021)","(ITPKA, 0)","(AKT3, -0.019)","(PITX2, -0.021)","(PDK1, -0.032)","(ITPR2, -0.033)","(PLD3, -0.037)","(IKBKG, -0.057)","(PLD2, -0.062)","(GNAQ, -0.103)","(NFKBIE, -0.104)","(ITPKB, -0.107)","(NFKBIL2, -0.123)","(AKT1, -0.128)"]
[321,"glycolipid metabolism (GO:0006664)",2,0.264,0.712,1,"(ST6GALNAC4, 0.003)","(ST3GAL6, 0.001)"]
[323,"isocitrate metabolism (GO:0006102)",2,0.265,0.712,0.77832,"(IDH1, 1.47)","(IDH3B, -0.36)"]
[324,"cell differentiation (GO:0030154)",12,0.266,0.716,0.58599,"(JAG2, 1.354)","(INHA, 0.601)","(SKIL, 0.446)","(TFIP11, 0.113)","(NDRG2, 0.036)","(TP53, 0.01)","(SMURF1, -0.037)","(INHBA, -0.093)","(TDGF1, -0.095)","(MAL, -0.148)","(IFRD2, -0.195)","(WNT1, -0.199)"]
[325,"ionPathway BioCarta",5,0.267,0.718,0.84472,"(PLCG1, 0.976)","(PTK2B, 0.96)","(PRKCB1, -0.135)","(P2RY2, -0.173)","(PRKCA, -0.246)"]
[325,"metabotropic glutamate receptor, phospholipase C activating pathway (GO:0007206)",2,0.267,0.718,0.9554,"(GRM5, 1.288)","(HOMER1, -0.095)"]
[327,"negative regulation of protein kinase activity (GO:0006469)",5,0.268,0.718,0.67581,"(SFN, 0.958)","(RB1, 0.662)","(PAK2, 0.167)","(YWHAH, 0.045)","(TRIB3, -0.049)"]
[328,"ahspPathway Alpha-hemoglobin stabilizing protein (AHSP) prevents precitipation of hemoglobin alpha-subunits.",11,0.27,0.718,1,"(ALAS1, 1.304)","(UROS, 0.694)","(ALAD, 0.501)","(GATA1, 0.199)","(HMBS, 0.097)","(ERAF, 0.03)","(UROD, -0.039)","(FECH, -0.082)","(ALAS2, -0.092)","(HBB, -0.104)","(HBA2, -0.121)"]
[329,"MAP00120 Bile acid biosynthesis GenMAPP",22,0.271,0.719,0.57041,"(ADH7, 1.509)","(CYP27A1, 0.502)","(ALDH2, 0.502)","(SRD5A1, 0.266)","(ADH5, 0.121)","(ADH1B, 0.112)","(ADH1C, 0.101)","(SRD5A2, 0.07)","(BAAT, 0.036)","(HADHB, 0.029)","(ADH6, 0.012)","(CEL, 0.009)","(ALDH3A2, -0.02)","(ACAA2, -0.046)","(ACAA1, -0.055)","(SOAT1, -0.063)","(ALDH1A1, -0.065)","(ADH1A, -0.084)","(ALDH1B1, -0.088)","(CYP7A1, -0.103)","(LIPA, -0.108)","(AKR1D1, -0.126)"]
[329,"nktPathway BioCarta",29,0.271,0.719,0.83847,"(IL4R, 0.972)","(IL12RB1, 0.52)","(CCL4, 0.287)","(IL12RB2, 0.267)","(IL12A, 0.248)","(CCR1, 0.216)","(CXCR4, 0.213)","(CD4, 0.191)","(CD28, 0.144)","(IL18R1, 0.139)","(IL12B, 0.133)","(IFNGR1, 0.117)","(CCL3, 0.097)","(IL5, 0.06)","(CSF2, 0.039)","(TNFSF5, 0.025)","(IFNGR2, 0.024)","(CCR2, -0.005)","(TGFB3, -0.008)","(CXCR3, -0.033)","(CCR7, -0.056)","(TGFB1, -0.064)","(TGFB2, -0.07)","(IL2, -0.078)","(CCR3, -0.116)","(CCR4, -0.118)","(IFNG, -0.125)","(IL4, -0.133)","(CCR5, -0.156)"]
[331,"negative regulation of macrophage differentiation (GO:0045650)",2,0.273,0.721,0.94068,"(INHA, 1.265)","(INHBA, -0.046)"]
[332,"AR MOUSE na",45,0.274,0.721,0.51818,"(AGR2, 1.001)","(ERP70, 0.626)","(FKBP11, 0.58)","(SC4MOL, 0.356)","(FDFT1, 0.355)","(ISYNA1, 0.277)","(CYB561, 0.237)","(GFRA1, 0.236)","(MAN1A1, 0.222)","(GPC1, 0.192)","(KCNK1, 0.167)","(NCF2, 0.122)","(GJB3, 0.085)","(ARAF1, 0.079)","(AGPAT3, 0.068)","(STMN1, 0.057)","(KLRB1, 0.046)","(TCF7, 0.035)","(GSTM1, 0.029)","(GLUL, 0.019)","(ADCY8, 0.015)","(ISG20, 0.007)","(KCNK7, 0.006)","(FKBP5, 0.006)","(RAMP3, 0)","(ADAM7, 0)","(NUCB2, 0)","(RRM1, 0)","(FDPS, 0)","(ACE, 0)","(CA4, -0.009)","(TPMT, -0.023)","(INDO, -0.032)","(ALPL, -0.045)","(GLDC, -0.047)","(KIAA0251, -0.05)","(ADRA2C, -0.055)","(PEMT, -0.068)","(ENPP1, -0.072)","(EBP, -0.095)","(BTG3, -0.096)","(GPX5, -0.1)","(PTPRO, -0.138)","(MYOM2, -0.156)","(CA2, -0.204)"]
[332,"chromatin silencing (GO:0006342)",5,0.274,0.721,0.84392,"(HDAC5, 1.131)","(TNP1, 0.601)","(SIRT5, -0.011)","(SIRT1, -0.068)","(SIRT4, -0.074)"]
[332,"mitotic anaphase (GO:0000090)",3,0.274,0.721,0.92567,"(NUMA1, 0.846)","(ANAPC5, 0.26)","(ANAPC10, 0.088)"]
[332,"spermatid development (GO:0007286)",4,0.274,0.721,0.99534,"(SPAG6, 0.511)","(NME5, 0.403)","(CSNK2A2, 0.323)","(BTG1, 0.157)"]
[336,"negative regulation of cell proliferation (GO:0008285)",109,0.275,0.723,0.56901,"(FABP6, 0.936)","(FTH1, 0.931)","(COL18A1, 0.419)","(RARRES1, 0.404)","(NDN, 0.311)","(NPM1, 0.267)","(IL1A, 0.23)","(CDKN2C, 0.219)","(ING1, 0.187)","(TM4SF4, 0.157)","(EMP3, 0.155)","(CD164, 0.153)","(CDKN1B, 0.149)","(NME2, 0.143)","(CHEK1, 0.133)","(CDKN3, 0.127)","(MXI1, 0.125)","(ALOX15B, 0.123)","(TNFRSF9, 0.121)","(GNRH1, 0.113)","(TNFRSF8, 0.106)","(GAS1, 0.1)","(BTG1, 0.09)","(MNT, 0.03)","(CUL1, 0.028)","(SSTR3, 0.025)","(CNOT8, 0.01)","(DLG5, 0.008)","(PLG, 0)","(BCL2, 0)","(NOTCH2, 0)","(CDKN1C, 0)","(OPRM1, 0)","(POU1F1, 0)","(ATP8A2, 0)","(CUL5, 0)","(ABI1, 0)","(KLF4, 0)","(NF2, 0)","(ING4, 0)","(ADRA1A, 0)","(APEG1, 0)","(FABP7, 0)","(NF1, 0)","(ADAMTS8, 0)","(MDM2, 0)","(AIF1, 0)","(CTBP2, 0)","(FRK, 0)","(CDK10, 0)","(IGFBP7, 0)","(CUL4A, 0)","(BTG2, 0)","(OSM, 0)","(PTHLH, 0)","(COL4A3, 0)","(PPM1D, 0)","(CDKN2B, 0)","(NME1, 0)","(CCL23, 0)","(CDKN2D, 0)","(IL6, 0)","(MXD4, 0)","(SESN1, 0)","(CDC7, 0)","(VHL, 0)","(RARRES3, 0)","(CTBP1, 0)","(FABP3, 0)","(CGREF1, 0)","(ETS1, 0)","(RBBP4, 0)","(PPAP2A, 0)","(CD33, 0)","(S100A11, 0)","(ADAMTS1, 0)","(PMP22, 0)","(TP53I11, 0)","(SIRPB2, 0)","(CUL2, 0)","(IGFBP6, 0)","(BTG3, 0)","(CDKN2A, 0)","(IL8, 0)","(MLLT7, 0)","(LDOC1, 0)","(SSTR5, 0)","(WARS, 0)","(IFITM1, 0)","(IL1B, 0)","(BTG4, 0)","(GML, 0)","(SSTR2, 0)","(TOB2, 0)","(UMOD, 0)","(GPNMB, 0)","(CDC6, 0)","(GAS8, 0)","(DRIM, 0)","(PRKRIR, 0)","(SSTR1, 0)","(CGRRF1, 0)","(MDM4, 0)","(TOB1, 0)","(PCAF, 0)","(CDKN1A, 0)","(BAI1, 0)","(SSTR4, -0.01)","(NCK2, -0.169)"]
[337,"vifPathway BLACK",3,0.277,0.726,0.93764,"(CD4, 0.893)","(CXCR4, 0.584)","(HCK, -0.267)"]
[337,"cdc42racPathway PI3 kinase stimulates cell migration by activating cdc42, which activates ARP2/3, which in turn promotes formation of new actin fibers.",14,0.277,0.726,1,"(ARPC1B, 0.832)","(ARPC3, 0.578)","(ARPC4, 0.482)","(RAC1, 0.391)","(ARPC1A, 0.323)","(ACTR3, 0.235)","(WASL, 0.081)","(PAK1, 0.033)","(PIK3R1, 0.009)","(PDGFRA, -0.073)","(ARPC2, -0.127)","(CDC42, -0.127)","(PIK3CA, -0.139)","(ACTR2, -0.171)"]
[337,"GPCRs Class C Metabotropic glutamate pheromone GO",14,0.277,0.726,1,"(GPRC5B, 0.813)","(GRM5, 0.557)","(GABBR1, 0.382)","(GPRC5D, 0.31)","(GRM4, 0.236)","(GRM2, 0.216)","(GRM8, 0.06)","(GPR51, 0.048)","(RAI3, -0.015)","(CASR, -0.025)","(GRM7, -0.081)","(GPRC5C, -0.089)","(GRM3, -0.133)","(GRM1, -0.161)"]
[340,"natriuresis (GO:0030147)",3,0.278,0.726,0.85654,"(NPR1, 1.206)","(NPPB, 0.104)","(KNG1, -0.052)"]
[341,"ER-associated protein catabolism (GO:0030433)",5,0.279,0.726,0.83304,"(EDEM1, 1.19)","(VCP, 0.13)","(KIAA0368, 0.127)","(UBA52, -0.036)","(AMFR, -0.063)"]
[341,"protein deubiquitination (GO:0016579)",2,0.279,0.726,0.86105,"(UCHL1, 1.454)","(USP33, -0.244)"]
[341,"insulin signalling BioCarta",102,0.279,0.726,0.96825,"(UCP2, 0.873)","(PIK3R3, 0.382)","(PCK2, 0.359)","(SLC2A4, 0.324)","(RPS6KB1, 0.323)","(G6PD, 0.314)","(CAP1, 0.297)","(AKT2, 0.269)","(CRK, 0.262)","(SREBF1, 0.224)","(DF, 0.221)","(JUN, 0.209)","(DUSP14, 0.202)","(NOS2A, 0.196)","(PRKCG, 0.195)","(ERCC1, 0.182)","(RRAS, 0.164)","(PKLR, 0.14)","(SERPINE1, 0.128)","(BRD4, 0.109)","(PIK3CB, 0.106)","(GSK3B, 0.085)","(UCP1, 0.075)","(CEBPB, 0.066)","(SORBS1, 0.054)","(NPY, 0.03)","(FOS, 0.023)","(PRKCZ, 0.016)","(LNPEP, 0)","(CSN2, 0)","(DOK1, 0)","(LEP, 0)","(PIK3R1, 0)","(EIF4EBP1, 0)","(HK2, 0)","(IRS1, 0)","(SERPINB6, 0)","(ARAF1, 0)","(PDPK1, 0)","(IGFBP1, 0)","(MKNK1, 0)","(GRB2, 0)","(HRAS, 0)","(TIEG, 0)","(PIK3CA, 0)","(PTPRF, 0)","(MAP2K2, 0)","(BCL2L1, 0)","(ACACB, 0)","(PRKCB1, 0)","(AEBP1, 0)","(GAB1, 0)","(AKT1, 0)","(FRAP1, 0)","(SOS2, 0)","(INS, 0)","(AKT3, 0)","(INSR, 0)","(GSK3A, 0)","(MAP2K1, 0)","(PPIA, 0)","(RAF1, 0)","(GCK, 0)","(CBL, 0)","(RETN, 0)","(SLC2A1, 0)","(G6PC, 0)","(GCG, 0)","(PRKCI, 0)","(PPARG, 0)","(ACOX1, 0)","(ADRB3, 0)","(SHC3, 0)","(VEGF, 0)","(RPS6KA1, 0)","(PIK3R2, 0)","(EIF2B1, 0)","(PTPN11, 0)","(RRAS2, 0)","(SOS1, 0)","(RPL13A, 0)","(EIF4E, 0)","(PTPN1, 0)","(NCK1, 0)","(CEBPA, 0)","(SHC1, 0)","(PRL, 0)","(KRAS2, 0)","(PKM2, 0)","(TG, 0)","(BRAF, 0)","(IRS4, 0)","(GAPD, 0)","(PPP1CA, 0)","(IRS2, 0)","(ORM1, 0)","(MAPK1, 0)","(NCK2, 0)","(ACTB, 0)","(LDLR, 0)","(ACACA, -0.015)","(FBP1, -0.016)"]
[341,"ER to Golgi vesicle-mediated transport (GO:0006888)",7,0.279,0.726,1,"(STX18, 1.182)","(BET1, 0.586)","(SEC22L1, 0.113)","(LMAN2L, 0.024)","(LMAN1, -0.018)","(GOSR2, -0.192)","(TXNDC, -0.206)"]
[345,"il1rPathway BioCarta",32,0.281,0.727,0.913,"(IL1RAP, 1.055)","(NFKBIA, 0.863)","(NFKB1, 0.67)","(IL1A, 0.366)","(SITPEC, 0.343)","(JUN, 0.291)","(IRAK1, 0.236)","(IL6, 0.171)","(MAPK14, 0.158)","(IL1RN, 0.131)","(IL1R1, 0.038)","(TGFB3, 0.007)","(MAP2K3, 0.003)","(TGFB2, 0)","(IL1B, -0.009)","(MAP3K7IP1, -0.011)","(MAP3K14, -0.016)","(IFNB1, -0.02)","(MAPK8, -0.02)","(IFNA1, -0.02)","(MAP3K7, -0.021)","(TOLLIP, -0.052)","(TNF, -0.052)","(TRAF6, -0.063)","(IKBKB, -0.063)","(CHUK, -0.067)","(MAP2K6, -0.083)","(IRAK3, -0.085)","(MYD88, -0.11)","(MAP3K1, -0.122)","(RELA, -0.149)","(TGFB1, -0.161)"]
[345,"regulation of actin polymerization and/or depolymerization (GO:0008064)",2,0.281,0.727,0.92051,"(CXCL12, 0.573)","(TMSB4Y, 0.341)"]
[347,"vipPathway BioCarta",26,0.284,0.737,1,"(NFKBIA, 0.943)","(NFKB1, 0.78)","(PLCG1, 0.491)","(NFATC1, 0.315)","(PRKACB, 0.195)","(PPP3CC, 0.191)","(PRKAR2A, 0.171)","(VIPR2, 0.152)","(PRKAR2B, 0.119)","(MYC, 0.049)","(PRKAR1B, 0.045)","(CALM2, 0.024)","(CALM1, 0)","(PPP3CA, -0.001)","(CHUK, -0.004)","(GNAQ, -0.057)","(EGR2, -0.077)","(MAP3K1, -0.092)","(PRKACG, -0.098)","(SYT1, -0.107)","(VIP, -0.108)","(CALM3, -0.134)","(EGR3, -0.138)","(PPP3CB, -0.155)","(PRKAR1A, -0.213)","(RELA, -0.225)"]
[348,"appPathway BLACK",3,0.285,0.741,0.7551,"(ADAM10, 0.434)","(APP, 0.359)","(PSEN1, 0.134)"]
[348,"substrate-bound cell migration (GO:0006929)",2,0.285,0.741,0.969,"(HAS1, 0.979)","(VEGFC, -0.074)"]
[348,"energy reserve metabolism (GO:0006112)",6,0.285,0.741,0.98211,"(GFPT1, 1.438)","(LEP, 0.185)","(ADRB3, 0.088)","(GFPT2, -0.004)","(S100B, -0.083)","(LEPR, -0.179)"]
[348,"second-messenger-mediated signaling (GO:0019932)",2,0.285,0.741,1,"(PPP2R1B, 0.457)","(DGKD, 0.296)"]
[352,"heparan sulfate proteoglycan biosynthesis (GO:0015012)",3,0.287,0.743,0.97982,"(NDST1, 1.234)","(EXT1, 0.082)","(GLCE, 0.032)"]
[353,"mspPathway BioCarta",6,0.289,0.745,0.87936,"(MST1, 1.054)","(CSF1, 0.461)","(IL1B, 0.077)","(MST1R, 0.02)","(TNF, -0.149)","(CCL2, -0.15)"]
[353,"carm-erPathway Methyltransferase CARM1 methylates CBP and co-activates estrogen receptors via Grip1.",27,0.289,0.745,0.88204,"(NCOR2, 1.14)","(SHARP, 0.723)","(HDAC5, 0.508)","(CARM1, 0.284)","(GRIP1, 0.182)","(GTF2E1, 0.165)","(HDAC1, 0.12)","(ERCC3, 0.101)","(BRCA1, 0.093)","(HDAC4, 0.07)","(HDAC2, 0.061)","(HDAC3, 0.047)","(EP300, 0.033)","(POLR2A, 0.024)","(PELP1, 0.02)","(ESR1, 0.009)","(TBP, -0.004)","(CCND1, -0.026)","(HDAC6, -0.027)","(CREBBP, -0.039)","(REA, -0.053)","(NR0B1, -0.084)","(GTF2F1, -0.105)","(NRIP1, -0.125)","(MEF2C, -0.127)","(PPARBP, -0.128)","(GTF2A1, -0.149)"]
[353,"arginine catabolism (GO:0006527)",4,0.289,0.745,0.93526,"(DDAH2, 0.791)","(DDAH1, 0.594)","(ASL, 0.053)","(ARG1, -0.028)"]
[356,"cell-matrix adhesion (GO:0007160)",19,0.29,0.745,0.62957,"(SGCE, 0.711)","(MKLN1, 0.542)","(THBS3, 0.501)","(PKD2, 0.245)","(COL17A1, 0.221)","(ITGA7, 0.174)","(PPFIA1, 0.151)","(PPFIA2, 0.12)","(ITGA10, 0.085)","(ITGA2, 0.079)","(ILK, 0.02)","(ECM2, -0.014)","(FXC1, -0.024)","(ANGPTL3, -0.039)","(CD47, -0.051)","(ITGA3, -0.075)","(ITGB1BP1, -0.118)","(FBLN5, -0.121)","(ADAM15, -0.176)"]
[356,"ROS Manually Curated",6,0.29,0.745,0.98654,"(GPX1, 1.478)","(GPX4, 0.232)","(PRDX6, 0.209)","(SOD2, -0.086)","(KIAA0963, -0.158)","(PRDX3, -0.253)"]
[358,"intrinsicPathway BioCarta",23,0.292,0.75,0.31098,"(SERPING1, 1.274)","(PROS1, 0.854)","(COL4A1, 0.469)","(F5, 0.32)","(F12, 0.259)","(KLKB1, 0.236)","(COL4A6, 0.158)","(FGA, 0.103)","(F2, 0.013)","(F11, 0)","(COL4A4, -0.006)","(FGG, -0.006)","(F9, -0.017)","(COL4A3, -0.027)","(F2R, -0.061)","(FGB, -0.065)","(COL4A2, -0.071)","(COL4A5, -0.078)","(F8, -0.088)","(SERPINC1, -0.096)","(F10, -0.11)","(KNG, -0.121)","(PROC, -0.135)"]
[358," (GO:0000067)",8,0.292,0.75,1,"(SUV39H1, 1.313)","(TOPBP1, 0.529)","(DNMT3B, 0.172)","(SMC2L1, 0.13)","(TEP1, -0.028)","(CENPE, -0.125)","(POLS, -0.149)","(CENPF, -0.219)"]
[360,"negative regulation of apoptosis (GO:0043066)",8,0.293,0.751,0.80877,"(BARD1, 1.288)","(CD74, 0.437)","(MIF, 0.243)","(TDGF1, 0.029)","(VEGF, 0.022)","(YWHAH, -0.01)","(ANGPTL4, -0.12)","(PROC, -0.177)"]
[360,"cytoplasmic sequestering of NF-kappaB (GO:0007253)",2,0.293,0.751,0.99978,"(FAF1, 0.576)","(BCL3, 0.348)"]
[362,"VOXPHOS BioCarta",85,0.294,0.751,0.51014,"(COX6A1, 0.494)","(ATP5I, 0.382)","(NDUFB3, 0.337)","(NDUFB4, 0.315)","(SURF1, 0.294)","(ATP5O, 0.291)","(ATP5J2, 0.264)","(NDUFA2, 0.24)","(NDUFB7, 0.218)","(NDUFB1, 0.213)","(NDUFA3, 0.213)","(BCS1L, 0.212)","(ATP5G2, 0.201)","(NDUFAB1, 0.185)","(GRIM19, 0.163)","(ATP5E, 0.157)","(ATP5C1, 0.137)","(ATP5D, 0.124)","(NDUFS2, 0.123)","(NDUFS3, 0.108)","(COX5B, 0.108)","(UQCR, 0.103)","(NDUFA8, 0.098)","(NDUFC1, 0.096)","(QP-C, 0.092)","(NDUFS1, 0.092)","(NDUFS7, 0.078)","(SDHC, 0.066)","(COX6A2, 0.056)","(COX7A2, 0.056)","(SDHB, 0.034)","(COX4I1, 0.03)","(COX7A1, 0.019)","(UQCRH, 0.009)","(NDUFC2, 0)","(NDUFA10, 0)","(NDUFB8, 0)","(UQCRFS1, 0)","(ATP5J, 0)","(MBD3, 0)","(NDUFB6, 0)","(UQCRC2, 0)","(COX15, 0)","(COX5A, 0)","(NDUFA6, 0)","(NGFRAP1, 0)","(NFKBIL2, 0)","(CYB5, 0)","(CKAP1, 0)","(LOC56901, 0)","(CYC1, 0)","(CYCS, 0)","(NDUFS8, 0)","(ATP5G3, 0)","(SDHD, 0)","(NDUFA5, 0)","(ATP5F1, 0)","(NDUFB2, 0)","(BCL2L1, 0)","(COX7A2L, 0)","(NDUFA7, 0)","(NDUFB5, 0)","(ZNF183, 0)","(COX6C, 0)","(PET112L, 0)","(NDUFS4, 0)","(NDUFA9, 0)","(ATP5L, 0)","(NDUFS6, 0)","(COX7C, 0)","(CNOT7, 0)","(ATP5H, 0)","(NDUFS5, 0)","(ATP5G1, 0)","(SURF2, 0)","(NDUFA4, 0)","(COX7B, 0)","(COX10, 0)","(COX6B, 0)","(HSPC051, 0)","(UQCRC1, 0)","(COX11, 0)","(SDHA, -0.015)","(UQCRB, -0.016)","(ATP5B, -0.046)"]
[362,"mRNA polyadenylylation (GO:0006378)",5,0.294,0.751,0.97183,"(CPSF1, 0.682)","(CSTF1, 0.288)","(GRSF1, 0.249)","(PABPC1, 0.169)","(CSTF2, 0.036)"]
[364,"ccr5Pathway CCR5 is a G-protein coupled receptor expressed in macrophages that recognizes chemokine ligands and is targeted by the HIV envelope protein GP120.",18,0.295,0.753,0.8688,"(PTK2B, 0.655)","(PLCG1, 0.603)","(JUN, 0.436)","(MAPK14, 0.295)","(CXCR4, 0.274)","(CCL4, 0.266)","(CXCL12, 0.22)","(FOS, 0.082)","(CALM1, 0.004)","(MAPK8, -0.01)","(CALM2, -0.028)","(GNAQ, -0.05)","(CALM3, -0.092)","(SYT1, -0.102)","(PRKCB1, -0.117)","(CCL2, -0.12)","(PRKCA, -0.134)","(CCR5, -0.183)"]
[365,"il18Pathway BioCarta",6,0.296,0.753,1,"(IL18, 0.785)","(IL12A, 0.57)","(IL12B, 0.236)","(CASP1, 0.065)","(IL2, -0.047)","(IFNG, -0.055)"]
[366,"vesicle targeting (GO:0006903)",2,0.298,0.757,0.98944,"(AP1M2, 0.752)","(STX5A, 0.243)"]
[367,"INS Manually Curated",25,0.3,0.762,0.75524,"(PIK3R3, 0.784)","(AKT2, 0.596)","(CRK, 0.53)","(CD4, 0.246)","(PIK3CB, 0.244)","(INPPL1, 0.237)","(PRKAR2B, 0.156)","(IGF1, 0.129)","(FLOT1, 0.118)","(SORBS1, 0.085)","(PDPK1, 0.073)","(IRS1, 0.052)","(NCK2, 0.026)","(SOS1, 0.019)","(NCK1, -0.002)","(INSR, -0.007)","(PRKCZ, -0.013)","(FLOT2, -0.034)","(PTPN6, -0.035)","(PIGF, -0.035)","(CBL, -0.055)","(AKT1, -0.067)","(PTEN, -0.154)","(IRS4, -0.157)","(PTPN1, -0.168)"]
[368,"MAP00220 Urea cycle and metabolism of amino groups GenMAPP",19,0.301,0.762,0.8882,"(CKB, 1.012)","(PYCR1, 0.896)","(SMS, 0.669)","(CKMT2, 0.509)","(ASS, 0.173)","(GAMT, 0.042)","(ASL, 0.036)","(ARG1, 0.017)","(ARG2, -0.011)","(PYCS, -0.019)","(CKMT1, -0.02)","(ODC1, -0.036)","(CKM, -0.047)","(ACY1, -0.064)","(GLUD1, -0.065)","(OAT, -0.078)","(VTI1B, -0.099)","(OTC, -0.128)","(CPS1, -0.225)"]
[369,"detection of bacteria (GO:0016045)",3,0.303,0.765,0.93305,"(PGLYRP1, 1.352)","(PGLYRP4, -0.12)","(CD1D, -0.212)"]
[369,"41bbPathway TNF-type receptor 4-1BB is bound by TRAF1 to activate the MAP kinase pathway in activated T cells.",18,0.303,0.765,1,"(NFKBIA, 1.101)","(NFKB1, 0.878)","(JUN, 0.433)","(ATF2, 0.383)","(TRAF2, 0.229)","(TNFRSF9, 0.227)","(MAPK14, 0.221)","(TNFSF9, 0.068)","(MAPK8, 0.038)","(MAP3K5, 0.002)","(MAP4K5, 0.002)","(CHUK, -0.046)","(IFNG, -0.068)","(IL2, -0.071)","(IKBKB, -0.08)","(IL4, -0.085)","(MAP3K1, -0.117)","(RELA, -0.233)"]
[371,"metabolism (GO:0008152)",15,0.304,0.768,0.55213,"(UGT2A1, 1.029)","(BDH, 0.715)","(GSTA1, 0.523)","(UGT2B4, 0.52)","(INSIG1, 0.469)","(AQP9, 0.006)","(PCSK1, -0.076)","(ABP1, -0.102)","(CPE, -0.12)","(PRNP, -0.129)","(UGT2B28, -0.144)","(FGF16, -0.147)","(CYP26A1, -0.154)","(MT, -0.158)","(CES1, -0.206)",{"$nulls":101},"(OPRM1, 0)","(C5R1, 0)","(NPY6R, 0)","(HTR1A, 0)","(DRD1, 0)","(TBXA2R, 0)","(HTR1B, 0)","(OR1F1, 0)","(GPR4, 0)","(P2RY1, 0)","(PTGFR, 0)","(ADRB1, 0)","(DRD2, 0)","(GPR44, 0)","(CCKBR, 0)","(PTGDR, 0)","(TRHR, 0)","(HCRTR1, 0)","(FBXW2, 0)","(HTR5A, 0)","(RGR, 0)","(GPR2, 0)","(PTAFR, 0)"]
[371,"torPathway BLACK",3,0.304,0.768,0.71613,"(IDH1, 1.338)","(IDH2, 0.039)","(ACO1, -0.418)"]
[371,"homophilic cell adhesion (GO:0007156)",8,0.304,0.768,0.94857,"(EVA1, 0.919)","(ITGA7, 0.243)","(PKD1, 0.237)","(CDH5, 0.212)","(TRO, 0.103)","(ITGB1, 0.039)","(MPZ, -0.124)","(ROBO1, -0.142)"]
[374,"DNA replication (GO:0006260)",30,0.305,0.771,0.85443,"(ACHE, 0.51)","(PTMS, 0.44)","(EGF, 0.305)","(RBMS1, 0.247)","(MCM7, 0.225)","(IGF1, 0.202)","(RPA3, 0.199)","(POLE3, 0.164)","(POLD2, 0.159)","(IGHMBP2, 0.158)","(RNASEH2A, 0.116)","(POLE, 0.115)","(HMGB2, 0.098)","(TREX1, 0.091)","(POLE2, 0.087)","(ORC3L, 0.081)","(NAP1L1, 0.063)","(DUT, 0.054)","(NUP98, 0.034)","(POLD4, 0.03)","(NT5M, 0.008)","(ECGF1, 0)","(MCM5, -0.007)","(SPHAR, -0.013)","(UBE1, -0.062)","(POLD1, -0.109)","(MCM3AP, -0.116)","(MCM2, -0.123)","(SET, -0.133)","(REV1L, -0.146)"]
[374,"skp2e2fPathway BioCarta",10,0.305,0.771,0.86625,"(SKP1A, 0.65)","(RB1, 0.396)","(CCNE1, 0.389)","(CUL1, 0.326)","(E2F1, 0.274)","(CCNA1, 0.103)","(CDK2, -0.019)","(TFDP1, -0.027)","(SKP2, -0.102)","(CDC34, -0.125)"]
[374,"UDP-glucose metabolism (GO:0006011)",2,0.305,0.771,0.88403,"(UGP2, 0.689)","(UGDH, 0.366)"]
[377,"protein amino acid methylation (GO:0006479)",3,0.306,0.771,0.95146,"(PCMT1, 0.621)","(HRMT1L1, 0.467)","(HRMT1L2, -0.104)"]
[378,"barbed-end actin filament capping (GO:0051016)",3,0.308,0.771,0.84817,"(EVL, 1.217)","(CAPG, 0.145)","(GSN, -0.195)"]
[378,"glycosphingolipid metabolism (GO:0006687)",2,0.308,0.771,0.98556,"(PSAP, 0.463)","(GALGT, 0.432)"]
[380,"mitosis (GO:0007067)",17,0.309,0.771,0.54883,"(BUB3, 0.62)","(DCTN2, 0.342)","(TARDBP, 0.29)","(MAD2L1, 0.278)","(CETN1, 0.159)","(CDC25B, 0.132)","(PPP5C, 0.109)","(PLK1, 0.089)","(KIF2C, 0.064)","(BUB1B, 0.06)","(AKAP8, 0.058)","(KIF22, 0.033)","(SSSCA1, 0.006)","(TPX2, -0.017)","(KATNA1, -0.024)","(NOLC1, -0.104)","(STK6, -0.148)"]
[381,"pattern specification (GO:0007389)",4,0.31,0.773,0.9616,"(HOXB1, 0.78)","(ZIC1, 0.264)","(MID1, 0.21)","(MFNG, -0.159)"]
[382,"SA CASPASE CASCADE SigmaAldrich",19,0.311,0.775,0.82077,"(DFFB, 0.469)","(BIRC3, 0.445)","(SREBF1, 0.405)","(CASP3, 0.369)","(SREBF2, 0.218)","(BIRC2, 0.169)","(TNFSF6, 0.144)","(BIRC4, 0.123)","(CASP10, 0.1)","(CASP8, 0.077)","(ADPRT, 0.05)","(TNFRSF6, 0.046)","(SCAP, 0.003)","(CASP7, 0.002)","(GZMB, -0.008)","(DFFA, -0.045)","(APAF1, -0.049)","(CASP9, -0.107)","(PRF1, -0.113)"]
[383,"mRNA stabilization (GO:0048255)",2,0.312,0.775,0.83047,"(PAIP1, 0.699)","(PABPC1, 0.098)"]
[383,"actin polymerization and/or depolymerization (GO:0008154)",4,0.312,0.775,0.95555,"(EVL, 1.146)","(WAS, 0.302)","(WASL, 0.136)","(WASPIP, -0.389)"]
[383,"raccycdPathway BioCarta",22,0.312,0.775,1,"(NFKBIA, 0.98)","(NFKB1, 0.82)","(RB1, 0.334)","(CCNE1, 0.298)","(RAC1, 0.283)","(CDKN1B, 0.243)","(E2F1, 0.186)","(MAPK3, 0.116)","(RAF1, 0.106)","(CCND1, 0.079)","(PIK3R1, 0.007)","(CDK2, -0.007)","(MAPK1, -0.009)","(PAK1, -0.011)","(HRAS, -0.025)","(CDKN1A, -0.037)","(CDK6, -0.048)","(PIK3CA, -0.064)","(TFDP1, -0.072)","(AKT1, -0.088)","(RELA, -0.1)","(CDK4, -0.111)"]
[386,"establishment and/or maintenance of cell polarity (GO:0007163)",10,0.313,0.775,0.74213,"(CAP1, 0.997)","(CRB1, 0.708)","(CCL4, 0.439)","(PARD3, 0.078)","(CD3G, -0.024)","(PARD6B, -0.052)","(CDC42, -0.101)","(SPN, -0.107)","(CAP2, -0.158)","(WNT1, -0.167)"]
[386,"synaptogenesis (GO:0007416)",7,0.313,0.775,0.7806,"(ACHE, 0.883)","(PCDHB11, 0.655)","(PCDHB3, 0.183)","(PCDHB6, -0.023)","(NRCAM, -0.098)","(POU4F1, -0.17)","(NLGN1, -0.207)"]
[386,"synaptonemal complex formation (GO:0007130)",2,0.313,0.775,0.96548,"(STAG3, 1.456)","(SC65, -0.473)"]
[386,"phototransduction (GO:0007602)",5,0.313,0.775,0.96605,"(UNC119, 0.614)","(PDC, 0.558)","(OPN1SW, -0.001)","(TRPC3, -0.042)","(NR2E3, -0.092)"]
[386,"sulfate transport (GO:0008272)",3,0.313,0.775,1,"(SLC13A4, 1.024)","(SLC26A4, 0.109)","(SLC26A2, 0.011)"]
[391,"locomotory behavior (GO:0007626)",3,0.314,0.775,0.93883,"(NPY2R, 0.585)","(NOVA1, 0.308)","(PGDS, 0.082)"]
[392,"fatty acid oxidation (GO:0019395)",3,0.315,0.775,0.83031,"(ADIPOR1, 0.505)","(ADIPOR2, 0.435)","(ALOX12, 0.102)"]
[393,"chromosome segregation (GO:0007059)",3,0.316,0.775,0.57572,"(RIOK3, 1.111)","(PSEN1, 0.179)","(PSEN2, -0.349)"]
[393,"DNA methylation (GO:0006306)",5,0.316,0.775,0.93385,"(DNMT1, 0.546)","(DNMT3A, 0.243)","(DNMT3B, 0.155)","(ATRX, 0.146)","(FOS, 0.132)"]
[395,"response to heat (GO:0009408)",2,0.317,0.776,0.73003,"(DNAJB4, 1.055)","(AKT1, -0.208)"]
[395,"response to UV (GO:0009411)",4,0.317,0.776,0.73653,"(SERPINB13, 1.689)","(REV1L, -0.125)","(POLD1, -0.247)","(GTF2H2, -0.294)"]
[395,"protein amino acid farnesylation (GO:0018347)",2,0.317,0.776,0.9672,"(FNTB, 0.889)","(FNTA, -0.028)"]
[398,"MAP00620 Pyruvate metabolism GenMAPP",31,0.318,0.776,0.89986,"(AKR1B1, 1.248)","(ALDH2, 0.442)","(ME2, 0.419)","(HAGH, 0.391)","(PDHB, 0.324)","(PKLR, 0.302)","(MDH1, 0.155)","(GLO1, 0.137)","(ACYP1, 0.126)","(ADH5, 0.055)","(ACAT1, 0.038)","(DLD, 0.017)","(PDHA1, 0.016)","(PKM2, 0.01)","(PDHA2, 0)","(GRHPR, -0.001)","(LDHB, -0.027)","(ACACA, -0.03)","(ACYP2, -0.043)","(DLAT, -0.045)","(PCK1, -0.06)","(PC, -0.065)","(LDHC, -0.079)","(ACACB, -0.083)","(ALDH1A1, -0.087)","(ME3, -0.096)","(ALDH3A2, -0.11)","(MDH2, -0.113)","(ALDH1B1, -0.121)","(LDHA, -0.163)","(ME1, -0.187)"]
[399,"peptidyl-tyrosine sulfation (GO:0006478)",2,0.319,0.776,0.75518,"(TPST2, 1.536)","(TPST1, -0.447)"]
[399,"chondroitin sulfate biosynthesis (GO:0030206)",4,0.319,0.776,0.82725,"(CHST3, 0.551)","(CHST7, 0.487)","(CHST11, 0.253)","(ChGn, 0.045)"]
[399,"ANTI CD44 DOWN Hogerkorp et al 2003",12,0.319,0.776,1,"(LAMP2, 1.119)","(PALM, 0.843)","(MLLT10, 0.571)","(SERPINA1, 0.116)","(HLCS, 0.008)","(PLS1, -0.035)","(EPHB3, -0.042)","(APC, -0.112)","(PRDM2, -0.119)","(GUCY2F, -0.127)","(SSTR4, -0.159)","(SLC14A1, -0.23)"]
[402,"cytochrome c oxidase complex assembly (GO:0008535)",2,0.32,0.776,0.91983,"(SURF1, 1.35)","(COX11, -0.294)"]
[403,"cytoplasmic sequestering of transcription factor (GO:0042994)",4,0.321,0.776,0.98397,"(NFKBIL1, 0.612)","(MXI1, 0.547)","(MDFI, -0.043)","(NFKBIE, -0.138)"]
[404,"detection of pest, pathogen or parasite (GO:0009596)",3,0.322,0.776,0.93803,"(HLA-DMA, 0.577)","(HLA-G, 0.493)","(HLA-DMB, 0.124)"]
[405,"cell fate determination (GO:0001709)",4,0.323,0.776,0.83421,"(NOTCH4, 1.204)","(MCL1, 0.385)","(NOTCH2, -0.134)","(DLL3, -0.248)"]
[406,"rac1Pathway BioCarta",22,0.324,0.779,0.26734,"(VAV1, 0.876)","(CFL1, 0.684)","(RPS6KB1, 0.67)","(MYLK, 0.294)","(ARFIP2, 0.255)","(RAC1, 0.233)","(PLD1, 0.09)","(NCF2, 0.073)","(WASF1, 0.056)","(RALBP1, 0.007)","(PDGFRA, 0)","(PIK3R1, -0.006)","(MAP3K1, -0.032)","(PAK1, -0.034)","(TRIO, -0.06)","(PPP1R12B, -0.072)","(MYL2, -0.073)","(CDK5, -0.087)","(PIK3CA, -0.096)","(CHN1, -0.143)","(LIMK1, -0.174)","(CDK5R1, -0.204)"]
[406,"histone phosphorylation (GO:0016572)",2,0.324,0.779,0.87991,"(RPS6KA5, 0.903)","(MAP3K12, 0.055)"]
[406,"parkinPathway BioCarta",8,0.324,0.779,1,"(SNCAIP, 0.94)","(SNCA, 0.308)","(GPR37, 0.294)","(UBE2L6, 0.219)","(UBE2G1, 0.2)","(PARK2, -0.073)","(UBE2L3, -0.099)","(UBE2G2, -0.154)"]
[409,"endosome transport (GO:0016197)",2,0.326,0.779,0.7318,"(TOM1, 0.605)","(ZFYVE16, 0.238)"]
[410,"acrosome reaction (GO:0007340)",3,0.327,0.783,0.81897,"(ACR, 1.264)","(AKAP3, 0.145)","(PKDREJ, -0.128)"]
[411,"Wnt Signaling BioCarta",54,0.328,0.783,0.97575,"(WNT5A, 0.879)","(WNT5B, 0.623)","(WNT4, 0.324)","(JUN, 0.301)","(PRKCG, 0.294)","(PPP2R5C, 0.281)","(WNT7B, 0.21)","(RAC1, 0.209)","(WNT16, 0.204)","(PRKCE, 0.183)","(GSK3B, 0.164)","(FZD8, 0.16)","(WNT2, 0.156)","(FZD3, 0.109)","(LDLR, 0.094)","(CSNK1E, 0.093)","(PRKCI, 0.093)","(PAFAH1B1, 0.09)","(MYC, 0.076)","(CCND1, 0.076)","(WNT3, 0.075)","(FZD5, 0.072)","(AXIN1, 0.062)","(TCF7, 0.046)","(FRAT1, 0.029)","(PRKCQ, 0.013)","(PRKCZ, 0.009)","(CTNNB1, 0)","(FZD9, 0)","(WNT2B, 0)","(PRKCH, 0)","(FZD6, 0)","(APC, 0)","(DIPA, 0)","(MAPK9, 0)","(FBXW2, 0)","(PRKCD, 0)","(PPP2R5E, 0)","(DVL1, 0)","(FZD2, 0)","(WNT6, -0.006)","(WNT11, -0.009)","(FZD10, -0.015)","(PRKCM, -0.019)","(DVL2, -0.02)","(DVL3, -0.039)","(WNT7A, -0.041)","(CCND2, -0.046)","(CCND3, -0.047)","(WNT10B, -0.052)","(SFRP4, -0.08)","(PRKCA, -0.119)","(MAPK10, -0.175)","(PLAU, -0.184)"]
[412,"plcPathway BioCarta",8,0.329,0.784,0.7621,"(VAV1, 1.272)","(PLCG1, 0.88)","(PIK3R1, -0.069)","(PIK3CA, -0.087)","(PLCB1, -0.133)","(AKT1, -0.149)","(PRKCB1, -0.153)","(PRKCA, -0.222)"]
[412,"UV protection (GO:0009650)",2,0.329,0.784,0.79361,"(FEN1, 0.371)","(MC1R, 0.358)"]
[412,"cellular respiration (GO:0045333)",2,0.329,0.784,0.86899,"(PPARGC1A, 0.347)","(CYCS, 0.332)"]
[412,"huntingtonPathway BLACK",4,0.329,0.784,0.88348,"(CREB1, 0.862)","(HDAC1, 0.253)","(HD, 0.113)","(CREBBP, -0.114)"]
[416,"response to DNA damage stimulus (GO:0006974)",5,0.33,0.786,0.99769,"(CIB1, 1.083)","(SESN1, 0.205)","(IRF7, -0.027)","(CHEK2, -0.04)","(DDIT3, -0.074)"]
[417,"thiamin metabolism (GO:0006772)",2,0.331,0.79,0.97832,"(THTPA, 1.142)","(TKTL1, -0.328)"]
[417,"MAP00860 Porphyrin and chlorophyll metabolism GenMAPP",18,0.331,0.79,0.98768,"(HCCS, 0.754)","(UROS, 0.546)","(UGT2B4, 0.486)","(BLVRB, 0.412)","(ALAD, 0.386)","(BLVRA, 0.094)","(HMBS, 0.055)","(GUSB, 0.048)","(CP, 0.033)","(ADH6, -0.024)","(HMOX1, -0.028)","(PYCS, -0.043)","(UROD, -0.046)","(UGT2B15, -0.066)","(HMOX2, -0.069)","(FDXR, -0.079)","(FECH, -0.083)","(EPRS, -0.142)"]
[417,"p27Pathway BioCarta",13,0.331,0.79,1,"(SKP1A, 0.585)","(RB1, 0.412)","(CDKN1B, 0.324)","(CCNE1, 0.3)","(E2F1, 0.275)","(CUL1, 0.257)","(UBE2M, 0.088)","(NEDD8, 0.047)","(SKP2, -0.035)","(RBX1, -0.045)","(CKS1B, -0.056)","(CDK2, -0.067)","(TFDP1, -0.111)"]
[420,"nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0006139)",27,0.332,0.79,0.85236,"(SLC29A1, 0.908)","(NP, 0.701)","(DPYSL3, 0.481)","(DPYSL2, 0.379)","(CTPS, 0.275)","(OAS1, 0.226)","(TK1, 0.225)","(CDA, 0.142)","(ERH, 0.113)","(OAS3, 0.092)","(SLC28A2, 0.061)","(CRMP1, 0.057)","(PAPSS1, 0.017)","(NUDT2, 0.016)","(ATIC, 0.011)","(SLC29A2, -0.003)","(BPNT1, -0.009)","(OAS2, -0.011)","(FPGS, -0.02)","(DPYS, -0.02)","(SLC28A1, -0.038)","(SLC23A2, -0.073)","(TPMT, -0.095)","(PAPSS2, -0.099)","(TK2, -0.129)","(TYMS, -0.14)","(MTAP, -0.167)"]
[420,"telomere maintenance (GO:0000723)",2,0.332,0.79,0.93541,"(TERT, 0.813)","(TEP1, 0.026)"]
[422,"positive regulation of nitric oxide biosynthesis (GO:0045429)",2,0.333,0.79,0.96102,"(HSPCB, 0.676)","(EGFR, 0.163)"]
[423,"cartilage condensation (GO:0001502)",7,0.334,0.79,0.82612,"(SNAI1, 0.518)","(SOX9, 0.429)","(COL11A1, 0.342)","(MATN1, 0.083)","(BMP1, 0.005)","(CART1, -0.05)","(MGP, -0.098)"]
[424,"nucleoside metabolism (GO:0009116)",2,0.335,0.793,0.98201,"(NME5, 0.449)","(NME4, 0.207)"]
[424,"postreplication repair (GO:0006301)",2,0.335,0.793,0.98966,"(MSH2, 0.684)","(UBE2A, 0.234)"]
[426,"copper ion transport (GO:0006825)",6,0.337,0.795,0.64775,"(ATP7A, 0.665)","(ATP7B, 0.395)","(ATOX1, 0.252)","(SLC31A1, 0.23)","(COX17, -0.12)","(SLC31A2, -0.281)"]
[427,"positive regulation of transcription, DNA-dependent (GO:0045893)",16,0.338,0.796,0,"(SMARCD3, 0.738)","(NOTCH4, 0.653)","(GATA4, 0.315)","(ILF3, 0.315)","(SMARCC1, 0.215)","(NSD1, 0.184)","(TBX5, 0.164)","(ESRRG, 0.03)","(TP73L, -0.04)","(ILF2, -0.068)","(MAP2K3, -0.091)","(CTCF, -0.103)","(SMARCC2, -0.115)","(CREB5, -0.122)","(ARHGEF11, -0.156)","(DYRK1B, -0.198)"]
[427,"cyclin catabolism (GO:0008054)",3,0.338,0.796,0.9504,"(CYB561D2, 0.849)","(ANAPC2, 0.3)","(UBE2C, -0.074)"]
[429,"erythPathway Erythropoietin selectively stimulates erythrocyte differentiation from CFU-GEMM cells in bone marrow.",15,0.339,0.797,0.48266,"(IL9, 0.789)","(IL1A, 0.619)","(CSF3, 0.618)","(CCL3, 0.216)","(IGF1, 0.148)","(IL6, 0.131)","(CSF2, 0.119)","(TGFB3, 0.048)","(EPO, 0.042)","(KITLG, -0.031)","(IL3, -0.064)","(TGFB1, -0.067)","(TGFB2, -0.111)","(FLT3, -0.138)","(IL11, -0.189)"]
[429,"regulation of heart contraction (GO:0008016)",20,0.339,0.797,0.53571,"(CYP2J2, 0.99)","(CACNA1H, 0.454)","(HSPB7, 0.355)","(KCNQ1, 0.282)","(KCNG2, 0.271)","(TNNT2, 0.245)","(CACNA1C, 0.239)","(CHRM2, 0.11)","(KCNH2, 0.099)","(TPM1, 0.038)","(KCNE2, -0.014)","(KCNE1L, -0.018)","(DES, -0.036)","(SCN5A, -0.042)","(KCNE1, -0.062)","(TNNI3, -0.073)","(KCNJ12, -0.078)","(SRI, -0.091)","(ADORA3, -0.126)","(RYR2, -0.173)"]
[431,"plcePathway BioCarta",12,0.34,0.799,1,"(GNAS, 0.651)","(PRKACB, 0.268)","(ADCY1, 0.241)","(ADRB2, 0.223)","(PRKAR2A, 0.21)","(PRKAR2B, 0.187)","(PRKAR1B, 0.141)","(PTGER1, 0.126)","(RAP2B, -0.06)","(PRKACG, -0.1)","(PLCE1, -0.137)","(PRKAR1A, -0.146)"]
[431,"intracellular virion transport (GO:0046795)",2,0.34,0.799,1,"(CD209, 0.002)","(CLEC4M, 0.001)"]
[433,"regulation of smoothened signaling pathway (GO:0008589)",2,0.343,0.805,1,"(ZIC1, 0.002)","(GLI1, 0.001)"]
[434,"HTERT UP Smith et al 2003",114,0.344,0.805,1,"(PYCR1, 0.428)","(GFPT1, 0.412)","(TGIF, 0.411)","(NFKB1, 0.399)","(MTHFD2, 0.388)","(SLC33A1, 0.366)","(SRP19, 0.359)","(HYOU1, 0.342)","(PPP1R11, 0.337)","(ICT1, 0.308)","(LMO4, 0.258)","(PIGH, 0.24)","(TSG101, 0.209)","(ZNF274, 0.206)","(TCTEL1, 0.2)","(PLEKHC1, 0.189)","(DCTN2, 0.182)","(KIAA0063, 0.16)","(TCEA1, 0.146)","(NEK3, 0.109)","(MICA, 0.094)","(LHFPL2, 0.089)","(IFRD1, 0.085)","(CDKN3, 0.08)","(CCNA1, 0.059)","(NFX1, 0.028)","(ch-TOG, 0.015)","(KIAA0073, 0.004)","(ATF3, 0)","(SFRS11, 0)","(ZNF165, 0)","(HERPUD1, 0)","(CCNH, 0)","(ILF2, 0)","(PSMD11, 0)","(ZFP36, 0)","(AHR, 0)","(MARS, 0)","(CDC6, 0)","(DAF, 0)","(MGEA6, 0)","(TOP1, 0)","(PSMD4, 0)","(DR1, 0)","(DYRK4, 0)","(NFIL3, 0)","(CREBBP, 0)","(RBM10, 0)","(CEBPG, 0)","(ETV6, 0)","(MCFD2, 0)","(TOMM34, 0)","(GOT1, 0)","(GSS, 0)","(CBX5, 0)","(GK, 0)","(MAPK9, 0)","(R3HDM, 0)","(GATA6, 0)","(A2LP, 0)","(DYRK1A, 0)","(DAP, 0)","(C11ORF4, 0)","(XBP1, 0)","(ASNS, 0)","(RAE1, 0)","(ELF4, 0)","(EIF2S1, 0)","(PSMD7, 0)","(CTH, 0)","(ALKBH, 0)","(AARS, 0)","(PCCB, 0)","(IL13RA2, 0)","(DGUOK, 0)","(CBLB, 0)","(EPHA2, 0)","(TNC, 0)","(XPC, 0)","(WASF1, 0)","(RPP30, 0)","(MLH1, 0)","(IL10RB, 0)","(COVA1, 0)","(EPS8, 0)","(CDKN2A, 0)","(KIAA0092, 0)","(SNRPA1, 0)","(NPC1, 0)","(BCL7B, 0)","(SH3BGR, 0)","(EGFR, 0)","(CLPP, 0)","(SCYE1, 0)","(ADAM8, 0)","(BMP2, 0)","(H1FX, 0)","(FGF2, 0)","(SLC1A5, 0)","(KLF5, 0)","(DUSP1, 0)","(DDX10, 0)","(GTF2E2, 0)","(HNRPD, 0)","(EWSR1, 0)","(CXCL2, 0)","(STK3, 0)","(NUP88, 0)","(HSF2, 0)","(PPP2R2A, 0)","(TRPC1, 0)","(MRPL49, 0)","(RDBP, 0)","(HUMAUANTIG, 0)"]
[435,"positive regulation of cell adhesion (GO:0045785)",4,0.346,0.809,0.8272,"(SAA1, 0.518)","(AZU1, 0.366)","(ALOX12, 0.127)","(TGM2, -0.008)"]
[436,"cxcr4Pathway CXCR4 is a G-protein coupled receptor that responds to the ligand SDF-1 by activating Ras and PI3 kinase to promote lymphocyte chemotaxis.",23,0.347,0.81,0.8228,"(NFKB1, 0.805)","(CRK, 0.581)","(PLCG1, 0.558)","(PTK2B, 0.509)","(CXCR4, 0.246)","(CXCL12, 0.19)","(RAF1, 0.128)","(GNB1, 0.076)","(PIK3C2G, 0.075)","(MAPK3, 0.002)","(HRAS, -0.02)","(GNAQ, -0.022)","(GNAI1, -0.026)","(MAPK1, -0.038)","(PTK2, -0.04)","(PIK3R1, -0.046)","(PRKCB1, -0.06)","(PXN, -0.063)","(MAP2K1, -0.069)","(RELA, -0.108)","(PIK3CA, -0.134)","(PRKCA, -0.152)","(GNGT1, -0.212)"]
[436,"DNA damage checkpoint (GO:0000077)",3,0.347,0.81,0.99308,"(CHES1, 0.755)","(CHEK1, 0.369)","(CHEK2, 0.059)"]
[438,"regulation of insulin secretion (GO:0050796)",3,0.35,0.817,0.91544,"(PPARD, 0.449)","(STX1A, 0.265)","(SNAP25, 0.235)"]
[438,"exocytosis (GO:0006887)",9,0.35,0.817,0.99265,"(VAPA, 1.045)","(ARFGEF2, 0.354)","(CCL3, 0.278)","(STX1A, 0.165)","(CCL8, -0.014)","(SCRN1, -0.09)","(CCL5, -0.113)","(LIN7A, -0.139)","(YWHAQ, -0.177)"]
[440,"stressPathway BioCarta",25,0.352,0.82,1,"(NFKBIA, 0.944)","(NFKB1, 0.762)","(TRADD, 0.711)","(JUN, 0.365)","(MAPK14, 0.213)","(TNFRSF1A, 0.206)","(TRAF2, 0.161)","(ATF1, -0.014)","(MAP4K2, -0.021)","(RIPK1, -0.022)","(TNF, -0.034)","(MAP2K3, -0.047)","(IKBKB, -0.068)","(MAP3K14, -0.079)","(CHUK, -0.079)","(LTA, -0.084)","(MAP3K1, -0.086)","(MAPK8, -0.086)","(CRADD, -0.089)","(MAP2K4, -0.102)","(TANK, -0.105)","(MAP2K6, -0.126)","(IKBKG, -0.128)","(RELA, -0.156)","(CASP2, -0.209)"]
[441,"activation of MAPK activity (GO:0000187)",16,0.353,0.821,0.57518,"(ADRA2A, 0.59)","(ADORA2B, 0.535)","(PIK3CB, 0.32)","(ADRB2, 0.272)","(CD81, 0.24)","(EGF, 0.237)","(FPR1, 0.183)","(C5, 0.134)","(CHRNA7, 0.076)","(SHC1, 0.006)","(TDGF1, -0.005)","(FGF2, -0.032)","(EDG5, -0.044)","(ADRA2C, -0.055)","(TRIB3, -0.056)","(C5R1, -0.166)"]
[442,"N-glycan processing (GO:0006491)",2,0.354,0.822,0.68193,"(FUT8, 0.939)","(MAN1A2, -0.148)"]
[442,"rhoPathway BioCarta",30,0.354,0.822,0.91338,"(ARHGAP4, 0.629)","(CFL1, 0.592)","(ARPC1B, 0.533)","(ARPC3, 0.382)","(DIAPH1, 0.368)","(ARPC4, 0.351)","(MYLK, 0.265)","(ARPC1A, 0.198)","(ACTR3, 0.112)","(ARHGAP5, 0.078)","(VCL, 0.074)","(PFN1, 0.069)","(ARHGEF5, 0.059)","(ROCK1, 0.058)","(ARHGEF1, 0.058)","(ARHGAP6, 0.051)","(OPHN1, 0.002)","(ARHGAP1, 0)","(MYL2, -0.009)","(PIP5K1A, -0.016)","(TLN1, -0.05)","(SRC, -0.07)","(PPP1R12B, -0.071)","(LIMK1, -0.095)","(PIP5K1B, -0.118)","(GSN, -0.122)","(ACTR2, -0.125)","(ARPC2, -0.128)","(BAIAP2, -0.144)","(ARHGEF11, -0.188)"]
[442,"SIG PIP3 signaling in B lymphocytes SignallingAlliance",35,0.354,0.822,0.95293,"(VAV1, 0.653)","(PLCG2, 0.568)","(RPS6KB1, 0.534)","(AKT2, 0.507)","(PHF11, 0.339)","(SAG, 0.261)","(BTK, 0.236)","(FLOT1, 0.192)","(FOXO3A, 0.16)","(RPS6KA2, 0.154)","(GAB1, 0.15)","(ITPR1, 0.102)","(P101-PI3K, 0.034)","(RPS6KA1, 0.02)","(ITPR3, 0.015)","(RPS6KA3, 0.002)","(CD19, 0)","(PPP1R13B, 0)","(PITX2, 0)","(CDKN2A, -0.01)","(ITPR2, -0.016)","(DAPP1, -0.017)","(FLOT2, -0.029)","(BCR, -0.033)","(PDK1, -0.043)","(PSCD3, -0.055)","(LYN, -0.072)","(PIK3CA, -0.09)","(NR0B2, -0.09)","(PTPRC, -0.101)","(TEC, -0.102)","(AKT3, -0.104)","(AKT1, -0.115)","(SYK, -0.124)","(PTEN, -0.169)"]
[445,"negative regulation of receptor mediated endocytosis (GO:0048261)",2,0.355,0.822,0.99824,"(RAC1, 0.928)","(ARF6, -0.109)"]
[446,"protein sumoylation (GO:0016925)",2,0.356,0.823,0.99469,"(SENP7, 0.45)","(SUMO1, 0.157)"]
[446,"tcraPathway BioCarta",12,0.356,0.823,1,"(CD3E, 0.429)","(HLA-DRB1, 0.391)","(CD4, 0.37)","(ZAP70, 0.322)","(FYN, 0.233)","(TRA@, 0.232)","(HLA-DRA, 0.02)","(PTPRC, -0.012)","(CD3D, -0.023)","(CD3G, -0.047)","(LCK, -0.151)","(CD3Z, -0.223)"]
[448,"ppargPathway BioCarta",8,0.357,0.827,0.94461,"(RXRA, 0.86)","(LPL, 0.666)","(PPARG, 0.08)","(EP300, 0.001)","(NCOA1, -0.029)","(NCOA2, -0.07)","(CREBBP, -0.087)","(PPARBP, -0.172)"]
[449,"protein processing (GO:0016485)",4,0.358,0.828,0.68583,"(NCSTN, 0.61)","(RNPEP, 0.496)","(PSEN1, 0.212)","(PSEN2, -0.271)"]
[449,"cell death (GO:0008219)",9,0.358,0.828,0.93864,"(EMP3, 0.505)","(FAF1, 0.426)","(FOSL2, 0.407)","(IL17, 0.339)","(EMP2, 0.095)","(EIF4G2, 0.058)","(PTGER3, -0.016)","(EMP1, -0.032)","(TNF, -0.106)"]
[451,"dbpbPathway BLACK",4,0.359,0.828,0.86228,"(PROCR, 0.494)","(PDGFB, 0.3)","(F2, 0.047)","(NSEP1, -0.003)"]
[451,"androgen metabolism (GO:0008209)",2,0.359,0.828,0.90899,"(AKR1C4, 0.472)","(SRD5A2, 0.36)"]
[453,"asbcellPathway B cells require interaction with helper T cells to produce antigen-specific immunoglobulins as a key element of the human immune response.",12,0.36,0.828,1,"(HLA-DRB1, 0.403)","(CD4, 0.364)","(CD28, 0.317)","(TNFSF6, 0.161)","(TNFRSF5, 0.15)","(TNFRSF6, 0.104)","(TNFSF5, 0.102)","(IL10, 0.07)","(HLA-DRA, 0.015)","(CD80, -0.03)","(IL2, -0.086)","(IL4, -0.16)"]
[454,"response to oxidative stress (GO:0006979)",18,0.361,0.83,0.81143,"(SOD1, 1.1)","(FOXM1, 0.588)","(PRDX2, 0.267)","(PRDX6, 0.198)","(ATOX1, 0.129)","(MPO, 0.121)","(SEPP1, 0.086)","(PNKP, 0.073)","(MSRA, 0.064)","(MTL5, 0.008)","(NUDT1, -0.005)","(SOD2, -0.027)","(SGK2, -0.038)","(STK25, -0.04)","(DUSP1, -0.041)","(GSS, -0.043)","(CCL5, -0.058)","(PDLIM1, -0.077)"]
[454,"DNA-dependent DNA replication (GO:0006261)",9,0.361,0.83,0.90271,"(RFC1, 0.51)","(REV3L, 0.34)","(CDK2AP1, 0.219)","(RPA2, 0.186)","(POLG2, 0.124)","(POLB, 0.065)","(RPA1, 0.063)","(TFAM, 0.051)","(POLG, -0.026)"]
[454,"protein secretion (GO:0009306)",9,0.361,0.83,0.94577,"(BACE2, 0.864)","(CANX, 0.57)","(ARFGAP3, 0.186)","(PPY, 0.183)","(PIGR, 0.056)","(LTBP2, -0.129)","(APBA2BP, -0.131)","(ARF4L, -0.167)","(SCG2, -0.192)"]
[454,"nucleosome disassembly (GO:0006337)",3,0.361,0.83,0.97897,"(TNP1, 0.753)","(SMARCE1, 0.093)","(SET, -0.024)"]
[458,"positive regulation of translation (GO:0045946)",2,0.362,0.832,0.83047,"(PAIP1, 0.67)","(PABPC1, 0.204)"]
[459,"brain development (GO:0007420)",20,0.363,0.832,0.7365,"(SLIT1, 1.399)","(UBE3A, 0.411)","(PHGDH, 0.254)","(NCOA6, 0.215)","(ZIC1, 0.128)","(POU6F1, 0.088)","(ALK, 0.025)","(TBR1, 0.016)","(LHX6, 0.016)","(SIX3, 0.014)","(FOXG1B, -0.011)","(CART1, -0.017)","(GPR56, -0.019)","(NKX2-2, -0.041)","(UNC5C, -0.053)","(ECE2, -0.053)","(NNAT, -0.066)","(DLX2, -0.069)","(EGR2, -0.098)","(HESX1, -0.182)"]
[459,"anterograde axon cargo transport (GO:0008089)",4,0.363,0.832,0.78446,"(KIF4A, 0.724)","(KIF3B, 0.276)","(KIF1B, 0.072)","(KIF1A, -0.139)"]
[459,"dreamPathway The transcription factor DREAM blocks expression of the prodynorphin gene, which encodes the ligand of an opioid receptor that blocks pain signaling.",13,0.363,0.832,1,"(JUN, 0.47)","(CREB1, 0.447)","(PRKACB, 0.303)","(PRKAR2B, 0.23)","(PRKAR2A, 0.228)","(FOS, 0.165)","(MAPK3, 0.1)","(POLR2A, 0.085)","(PRKAR1B, 0.081)","(OPRK1, 0.066)","(PRKAR1A, -0.092)","(PRKACG, -0.126)","(CREM, -0.137)"]
[462,"sensory perception (GO:0007600)",11,0.364,0.832,0.60287,"(NTSR2, 0.808)","(ADORA2A, 0.557)","(OPRL1, 0.266)","(PNOC, 0.09)","(BDKRB2, 0.087)","(OPRK1, 0.06)","(OPRD1, 0.045)","(TRPV2, 0.029)","(CCKBR, -0.036)","(OPRM1, -0.151)","(SCN10A, -0.152)"]
[462,"regulation of translation (GO:0006445)",14,0.364,0.832,0.72614,"(MAPK13, 0.632)","(RBMS2, 0.546)","(EPM2A, 0.532)","(RBMS1, 0.349)","(PPP2R1B, 0.282)","(MKNK2, 0.079)","(FRAP1, 0.064)","(PRKRIR, 0.04)","(TNIK, 0.016)","(MKNK1, -0.076)","(METAP2, -0.084)","(EIF4EBP2, -0.108)","(EIF4EBP1, -0.175)","(SKIV2L, -0.18)"]
[462,"bcl2family and reg network GEArray",23,0.364,0.832,1,"(BAG1, 0.732)","(AKT2, 0.638)","(SFN, 0.464)","(BCL6, 0.286)","(BAK1, 0.153)","(MCL1, 0.137)","(IGF1, 0.093)","(BCL2L2, 0.041)","(BAD, 0.04)","(BAX, 0.033)","(BCL2, 0.014)","(IL3, 0)","(GAPD, -0.004)","(BCL2A1, -0.004)","(BIK, -0.017)","(CASP8, -0.026)","(ACTB, -0.036)","(APAF1, -0.074)","(APBA2BP, -0.075)","(NCBP2, -0.111)","(AKT1, -0.118)","(BID, -0.126)","(BCL2L1, -0.142)"]
[465,"tnfr2Pathway BioCarta",18,0.365,0.832,0.7083,"(NFKBIA, 1.123)","(NFKB1, 0.899)","(TNFAIP3, 0.351)","(IKBKAP, 0.232)","(TRAF2, 0.225)","(TRAF3, 0.137)","(TRAF1, 0.042)","(DUSP1, -0.008)","(CHUK, -0.02)","(TNFRSF1B, -0.033)","(TANK, -0.047)","(RIPK1, -0.05)","(IKBKG, -0.051)","(LTA, -0.056)","(MAP3K14, -0.107)","(MAP3K1, -0.134)","(IKBKB, -0.146)","(RELA, -0.218)"]
[465,"protein amino acid N-linked glycosylation (GO:0006487)",15,0.365,0.832,0.92208,"(PMM2, 0.412)","(TM4SF4, 0.386)","(GYPC, 0.352)","(MGAT2, 0.342)","(DOLPP1, 0.212)","(MAN1C1, 0.163)","(ALG6, 0.155)","(LIPC, 0.131)","(KEL, 0.043)","(ALK, -0.017)","(CD37, -0.061)","(GAL3ST1, -0.104)","(GCS1, -0.127)","(TM4SF5, -0.131)","(LIPA, -0.174)"]
[465,"regulation of smooth muscle contraction (GO:0006940)",5,0.365,0.832,0.98517,"(MRCL3, 0.539)","(NMU, 0.364)","(CNN1, 0.357)","(PRKG1, -0.084)","(KCNB2, -0.139)"]
[468,"nucleosome spacing (GO:0016584)",2,0.366,0.832,0.90556,"(SMARCA5, 0.689)","(HBXAP, -0.241)"]
[469,"pparaPathway BioCarta",54,0.367,0.834,0.84394,"(NCOR2, 0.887)","(NFKBIA, 0.708)","(RXRA, 0.354)","(LPL, 0.334)","(HSPA1A, 0.329)","(NOS2A, 0.308)","(JUN, 0.257)","(RB1, 0.218)","(FABP1, 0.169)","(PRKACB, 0.142)","(CITED2, 0.136)","(APOA2, 0.129)","(APOA1, 0.116)","(PRKAR2A, 0.115)","(PRKAR2B, 0.054)","(MAPK3, 0.041)","(PRKAR1B, 0.035)","(CPT1B, 0.028)","(DUT, 0.025)","(DUSP1, 0.023)","(STAT5A, 0.016)","(PPARA, 0.009)","(PDGFA, 0.008)","(NR2F1, 0)","(RELA, 0)","(PRKACG, 0)","(ACOX1, 0)","(MYC, 0)","(EP300, 0)","(FAT, 0)","(PTGS2, 0)","(STAT5B, 0)","(INS, 0)","(PPARBP, 0)","(ME1, 0)","(MAPK1, 0)","(PIK3R1, -0.003)","(MRPL11, -0.007)","(PRKCB1, -0.008)","(NR1H3, -0.023)","(NR0B2, -0.025)","(PRKAR1A, -0.025)","(PRKCA, -0.032)","(NCOA1, -0.047)","(NCOR1, -0.056)","(HSD17B4, -0.059)","(TNF, -0.06)","(CREBBP, -0.077)","(PIK3CA, -0.08)","(EHHADH, -0.097)","(SP1, -0.12)","(HSPCA, -0.145)","(NRIP1, -0.176)","(CD36, -0.192)"]
[469,"folic acid transport (GO:0015884)",4,0.367,0.834,0.98609,"(FOLR1, 0.907)","(SLC19A1, 0.341)","(FOLR2, -0.005)","(FOLR3, -0.216)"]
[471,"chromatin assembly or disassembly (GO:0006333)",3,0.368,0.834,1,"(HIRIP3, 1.616)","(MTA2, -0.343)","(SUV39H2, -0.377)"]
[472,"enhancement of virulence (GO:0046800)",2,0.369,0.834,1,"(CD209, 0.002)","(CLEC4M, 0.001)"]
[473,"XINACT MERGED na",20,0.37,0.834,0.38111,"(PIR, 1.956)","(TMSB4X, 0.418)","(RPS4X, 0.244)","(USP9X, 0.223)","(STS, 0.207)","(ARSD, 0.015)","(EIF1AX, -0.01)","(TBL1X, -0.021)","(OFD1, -0.053)","(GRPR, -0.056)","(DDX3X, -0.067)","(PCTK1, -0.069)","(UTX, -0.105)","(UBE1, -0.108)","(ATP6AP2, -0.117)","(CA5B, -0.121)","(INE1, -0.125)","(ZFX, -0.126)","(PRKX, -0.135)","(EIF2S3, -0.23)"]
[473,"organ morphogenesis (GO:0009887)",55,0.37,0.834,0.59341,"(SCGB1A1, 1.326)","(TLE1, 0.594)","(COL18A1, 0.536)","(HCCS, 0.416)","(KLF1, 0.245)","(GNPAT, 0.203)","(ONECUT2, 0.197)","(COL9A1, 0.163)","(PKD2, 0.163)","(GYPC, 0.145)","(ELN, 0.125)","(NKX6-1, 0.122)","(FABP1, 0.117)","(SIX6, 0.107)","(ITGAX, 0.103)","(PITX3, 0.066)","(COL3A1, 0.06)","(PAX6, 0.037)","(BRAF, 0.035)","(ETV7, 0.029)","(FOXN1, 0.025)","(TLE2, 0.024)","(PITX2, 0.022)","(CDX2, 0.02)","(CDX1, 0.018)","(ABLIM1, 0.016)","(POU3F4, 0.008)","(TLE3, 0)","(TGFB3, 0)","(SFTPB, 0)","(HD, 0)","(FGD1, 0)","(IPF1, 0)","(COL5A3, 0)","(ITGA2, 0)","(EPHB4, 0)","(FLI1, 0)","(AES, 0)","(SPRY2, 0)","(CRX, 0)","(EPIM, -0.007)","(ENG, -0.018)","(IL7, -0.023)","(HRAS, -0.033)","(POU1F1, -0.041)","(FGF16, -0.045)","(GLI2, -0.059)","(DCN, -0.077)","(DGCR2, -0.085)","(DGCR6, -0.09)","(SYK, -0.096)","(CCL2, -0.097)","(LHX3, -0.107)","(KITLG, -0.116)","(PAX4, -0.174)"]
[473,"mitochondrial transport (GO:0006839)",2,0.37,0.834,0.99158,"(STARD3, 0.538)","(MTX2, 0.07)"]
[476,"arapPathway ADP-ribosylation factors (ARFs), members of the Ras superfamily, regulate eukaryotic vesicular trafficking and activate phospholipase D's.",21,0.371,0.834,0,"(DDEF2, 0.5)","(KDELR2, 0.457)","(CLTB, 0.327)","(GPLD1, 0.265)","(ARFGEF2, 0.241)","(CENTD1, 0.217)","(COPA, 0.167)","(ARFGAP3, 0.136)","(CLTA, 0.086)","(DDEF1, 0.084)","(BIG1, 0.068)","(PSCD2, 0.066)","(KDELR1, 0.006)","(KDELR3, 0)","(GBF1, -0.007)","(PSCD3, -0.074)","(CENTD2, -0.091)","(ARF1, -0.097)","(PSCD4, -0.114)","(ARFGAP1, -0.13)","(PSCD1, -0.162)"]
[476,"ST Interleukin 13 Pathway Signalling Transduction KE",7,0.371,0.834,0.96099,"(IL4R, 1.725)","(JAK1, 0.096)","(IL13, -0.001)","(TYK2, -0.01)","(IL13RA2, -0.035)","(IL13RA1, -0.245)","(JAK2, -0.291)"]
[476,"hifPathway BioCarta",15,0.371,0.834,1,"(HIF1A, 0.575)","(CREB1, 0.463)","(JUN, 0.433)","(P4HB, 0.398)","(COPS5, 0.232)","(ASPH, 0.16)","(VHL, 0.022)","(EP300, 0.011)","(EPO, -0.011)","(LDHA, -0.065)","(VEGF, -0.085)","(ARNT, -0.09)","(HSPCA, -0.095)","(NOS3, -0.15)","(EDN1, -0.155)"]
[479,"ST T Cell Signal Transduction Signalling Transduction KE",43,0.373,0.834,0.47741,"(NFKBIA, 0.781)","(VAV1, 0.654)","(NFKB1, 0.652)","(PLCG1, 0.409)","(CSK, 0.365)","(CD28, 0.186)","(NFKBIL1, 0.18)","(DAG1, 0.174)","(ZAP70, 0.152)","(NFKB2, 0.133)","(LCP2, 0.13)","(GRAP2, 0.117)","(SOS2, 0.093)","(NCK1, 0.07)","(RAF1, 0.042)","(PAK7, 0.021)","(DTYMK, 0.02)","(PAK6, 0.006)","(LAT, 0)","(SOS1, 0)","(PAK3, 0)","(NFKBIB, 0)","(CBL, 0)","(ITPKA, 0)","(MAPK1, 0)","(PAK2, 0)","(RASGRP3, -0.003)","(NFAT5, -0.005)","(FBXW7, -0.006)","(PAK4, -0.015)","(GRB2, -0.019)","(CTLA4, -0.032)","(RASGRP2, -0.036)","(RASGRP1, -0.047)","(NFKBIL2, -0.07)","(CD3D, -0.071)","(NFKBIE, -0.092)","(PTPRC, -0.094)","(PAK1, -0.096)","(EPHB2, -0.108)","(ITK, -0.122)","(ITPKB, -0.133)","(LCK, -0.151)"]
[479,"activation of MAPKKK activity (GO:0000185)",4,0.373,0.834,0.95189,"(GADD45G, 0.483)","(GADD45B, 0.387)","(MAP3K7IP1, 0.095)","(MAP4K1, 0.06)"]
[479,"protein tetramerization (GO:0051262)",3,0.373,0.834,0.98005,"(TRPV5, 0.614)","(AASS, 0.127)","(TP53, 0.075)"]
[479,"negative regulation of protein biosynthesis (GO:0017148)",2,0.373,0.834,1,"(NDUFA13, 0.002)","(PRKAA1, 0.002)"]
[483,"N-acetylglucosamine metabolism (GO:0006044)",8,0.374,0.834,0.96303,"(CHST4, 1.552)","(CHST7, 0.312)","(EXTL2, 0.036)","(CHST5, 0.033)","(NAGK, -0.028)","(CHST6, -0.104)","(LARGE, -0.214)","(CHST2, -0.222)"]
[484,"MAP00410 beta Alanine metabolism GenMAPP",17,0.375,0.834,0.8996,"(SMS, 0.684)","(GAD1, 0.619)","(ALDH2, 0.592)","(HADHA, 0.351)","(ABAT, 0.22)","(AOC3, 0.153)","(ECHS1, 0.104)","(ACADM, 0.045)","(ALDH1B1, -0.056)","(ALDH1A1, -0.058)","(AOC2, -0.06)","(DPYD, -0.068)","(DPYS, -0.08)","(ALDH3A2, -0.086)","(ABP1, -0.134)","(GAD2, -0.166)","(EHHADH, -0.187)"]
[484,"cell growth (GO:0016049)",8,0.375,0.834,0.91734,"(P8, 0.219)","(TNN, 0.219)","(FGF20, 0.191)","(DGKD, 0.173)","(ERBB2IP, 0.167)","(ESR1, 0.131)","(FRAP1, 0.038)","(NOTCH2, 0.002)"]
[484,"cytokinePathway Intercellular signaling in the immune system occurs via secretion of cytokines, which promote antigen-dependent B and T cell response.",21,0.375,0.834,0.99057,"(IL9, 0.68)","(IL1A, 0.482)","(IL18, 0.363)","(IL12A, 0.313)","(IL16, 0.277)","(IL17, 0.247)","(IL12B, 0.129)","(IL6, 0.128)","(IL5, 0.063)","(IL10, 0.033)","(IL13, -0.005)","(IL3, -0.008)","(IL2, -0.019)","(LTA, -0.035)","(IFNB1, -0.047)","(IL4, -0.058)","(TNF, -0.062)","(IL8, -0.072)","(IL15, -0.079)","(IFNG, -0.087)","(IFNA1, -0.088)"]
[487,"T-helper 2 type immune response (GO:0042092)",3,0.376,0.834,1,"(IL18, 0.924)","(IL10, 0.126)","(IL4, -0.269)"]
[488,"G-protein signaling, coupled to cAMP nucleotide second messenger (GO:0007188)",20,0.377,0.834,0.56515,"(MC4R, 0.591)","(ADORA2A, 0.476)","(GRK5, 0.394)","(ADRA1B, 0.315)","(FPR1, 0.191)","(ADRB2, 0.187)","(CHRM2, 0.113)","(GALR2, 0.1)","(GLP2R, 0.094)","(GCGR, 0.094)","(ADRB3, 0.075)","(AVPR2, 0.001)","(CRHR2, -0.022)","(PTGER4, -0.046)","(CCR3, -0.063)","(CALCA, -0.063)","(CRHR1, -0.08)","(GHRH, -0.081)","(WASF2, -0.082)","(ADRA1D, -0.088)"]
[488,"cskPathway Csk inhibits T-cell activation by phosphorylating Lck; Csk is regulated by cAMP-dependent kinases and is opposed by the T-cell activator CD45.",23,0.377,0.834,0.94925,"(GNAS, 0.5)","(CSK, 0.427)","(HLA-DRB1, 0.308)","(CD4, 0.28)","(CD3E, 0.244)","(ZAP70, 0.218)","(PRKACB, 0.202)","(ADCY1, 0.164)","(TRA@, 0.162)","(PRKAR2A, 0.139)","(PRKAR2B, 0.121)","(GNB1, 0.052)","(PRKAR1B, 0.007)","(HLA-DRA, -0.009)","(PTPRC, -0.03)","(PRKACG, -0.037)","(LCK, -0.039)","(CD3G, -0.048)","(CD3D, -0.068)","(CREBBP, -0.108)","(PRKAR1A, -0.162)","(GNGT1, -0.17)","(CD3Z, -0.172)"]
[490,"cardioblast differentiation (GO:0010002)",2,0.378,0.834,0.94762,"(BMP10, 0.885)","(ECE2, -0.079)"]
[490,"regulation of striated muscle contraction (GO:0006942)",6,0.378,0.834,0.9881,"(TNNT3, 0.895)","(ATP2A1, 0.361)","(MYBPC3, 0.157)","(MYL2, 0.051)","(MYBPH, -0.048)","(SRI, -0.154)"]
[490,"regulation of peptidyl-tyrosine phosphorylation (GO:0050730)",2,0.378,0.834,1,"(ITGB2, 0.577)","(EGFR, 0.143)"]
[493,"establishment and/or maintenance of epithelial cell polarity (GO:0045197)",3,0.379,0.836,0.9151,"(PRKCI, 0.502)","(ERBB2IP, 0.469)","(MARK2, -0.06)"]
[493,"GLUCOSE UP Peng at al 2002",40,0.379,0.836,1,"(PYCR1, 0.674)","(PCK2, 0.548)","(SC4MOL, 0.388)","(GART, 0.342)","(TCF20, 0.33)","(FKBP2, 0.308)","(KIAA0685, 0.257)","(UNC119, 0.251)","(EMS1, 0.176)","(MGST2, 0.171)","(CARS, 0.163)","(PLOD, 0.139)","(ACTA1, 0.126)","(URKL1, 0.113)","(HNRPDL, 0.091)","(CEBPB, 0.079)","(MS4A2, 0.066)","(24432, 0.047)","(TOMM40, 0.018)","(MS4A1, 0.01)","(GM2A, 0)","(ADA, -0.007)","(WARS, -0.007)","(POU2F2, -0.008)","(IDH2, -0.014)","(ASNS, -0.027)","(CROC4, -0.034)","(IGHM, -0.036)","(DRAP1, -0.04)","(FLJ22531, -0.053)","(AARS, -0.056)","(BCAT2, -0.067)","(MFNG, -0.096)","(MYB, -0.105)","(ATF5, -0.112)","(CORO1A, -0.113)","(OCLN, -0.114)","(MAP2K3, -0.114)","(CLCN6, -0.12)","(LTBR, -0.121)"]
[495,"ADULT LIVER vs FETAL LIVER GNF2 Manually Curated",78,0.38,0.837,0.94795,"(AZGP1, 0.853)","(CYP2A6, 0.722)","(ABHD2, 0.334)","(CYP27A1, 0.332)","(CYP2E1, 0.302)","(FLJ13798, 0.296)","(ITIH4, 0.269)","(WARP, 0.231)","(GPD1, 0.224)","(HAMP, 0.207)","(NNMT, 0.201)","(LGALS1, 0.171)","(RODH-4, 0.171)","(CYP2B6, 0.167)","(C8G, 0.158)","(CD14, 0.156)","(MYH7B, 0.154)","(CD81, 0.148)","(GSTZ1, 0.123)","(CD151, 0.113)","(PPP1R1A, 0.108)","(ADH1C, 0.104)","(PKLR, 0.099)","(ABCC3, 0.079)","(CYP4A11, 0.071)","(IGF1, 0.037)","(C1R, 0.009)","(SLC25A10, 0.008)","(NDUFA7, 0.008)","(RODH, 0)","(IGFALS, 0)","(HLA-DQB1, 0)","(C6orf108, 0)","(UPB1, 0)","(APCS, 0)","(RARRES2, 0)","(PTGDS, 0)","(DKFZP586B1621, 0)","(ACY1, 0)","(IFITM1, 0)","(SLC22A1, 0)","(G1P2, 0)","(PCK1, 0)","(HSD11B1, 0)","(DCPS, 0)","(CES2, 0)","(COMT, 0)","(CLPP, 0)","(DKFZp451J0118, 0)","(HPD, 0)","(CES1, 0)","(RAB26, 0)","(STAP2, 0)","(NKG7, 0)","(GSTM1, 0)","(HGFAC, 0)","(CYP1A2, 0)","(FLJ10847, 0)","(MGC10334, 0)","(ECHS1, 0)","(DEXI, 0)","(AQP9, 0)","(UQCRC1, 0)","(MUCDHL, 0)","(TXNRD2, 0)","(SDS, -0.005)","(GPR30, -0.007)","(ASL, -0.01)","(NRTN, -0.016)","(SIGIRR, -0.018)","(ENDOG, -0.023)","(APOC4, -0.03)","(CYP2C9, -0.033)","(SLC27A5, -0.041)","(KIAA1847, -0.051)","(HLA-DQA1, -0.078)","(CYP2C8, -0.105)","(SHMT2, -0.107)"]
[495,"cardiacegfPathway Cardiac hypertrophy, a response to high blood pressure, is stimulated by GPCR ligands such as angiotensin II that activate the EGF pathway.",17,0.38,0.837,1,"(NFKB1, 0.944)","(PLCG1, 0.609)","(JUN, 0.42)","(EGF, 0.29)","(FOS, 0.128)","(MYC, 0.09)","(AGT, 0.029)","(EDNRA, 0.024)","(EGFR, 0.01)","(AGTR2, -0.029)","(ADAM12, -0.035)","(HRAS, -0.049)","(PRKCB1, -0.088)","(EDNRB, -0.128)","(PRKCA, -0.138)","(EDN1, -0.161)","(RELA, -0.2)"]
[497,"frizzled signaling pathway (GO:0007222)",6,0.382,0.84,0.92108,"(FZD4, 0.959)","(FZD3, 0.297)","(FZD9, 0.176)","(FZD7, 0.036)","(FZD6, -0.001)","(FZD10, -0.235)"]
[497,"agpcrPathway G-protein coupled receptors (GPCRs) transduce extracellular signals across the plasma membrane; attenuation occurs by signal molecule degradation or receptor-mediated endocytosis.",12,0.382,0.84,1,"(ARRB1, 0.926)","(GNAS, 0.669)","(PRKAR2A, 0.282)","(PRKACB, 0.227)","(PRKAR2B, 0.19)","(PRKAR1B, 0.14)","(GNB1, 0.052)","(PRKACG, -0.107)","(PRKCB1, -0.116)","(PRKAR1A, -0.169)","(PRKCA, -0.186)","(GNGT1, -0.215)"]
[499,"muscle myosin BioCarta",15,0.383,0.84,0.7098,"(MYL5, 0.385)","(MYL4, 0.354)","(MYH8, 0.327)","(MYL9, 0.274)","(MRCL3, 0.231)","(MYL6, 0.161)","(MYL1, 0.115)","(MYL3, 0.05)","(MYH4, 0.049)","(HUMMLC2B, 0.037)","(MYH6, -0.041)","(MYH11, -0.057)","(MYO1A, -0.067)","(MYH7, -0.071)","(MYH1, -0.171)"]
[499,"Golgi organization and biogenesis (GO:0007030)",4,0.383,0.84,0.84224,"(GOLGB1, 0.604)","(COG2, 0.281)","(SEC23IP, 0.132)","(SYNE1, -0.189)"]
[499,"negative regulation of angiogenesis (GO:0016525)",7,0.383,0.84,0.95232,"(NPR1, 0.904)","(STAB1, 0.765)","(COL4A3, 0.095)","(NPPB, 0.048)","(PF4, -0.107)","(SERPINF1, -0.138)","(TNNI3, -0.212)"]
[499,"macrophage differentiation (GO:0030225)",2,0.383,0.84,0.96677,"(CSF1, 0.88)","(CDC42, -0.112)"]
[499,"GPI anchor biosynthesis (GO:0006506)",4,0.383,0.84,0.99931,"(PIGH, 1.115)","(PIGF, 0.071)","(PIGO, -0.073)","(PIGC, -0.09)"]
[499,"MAP00601 Blood group glycolipid biosynthesis lact series GenMAPP",6,0.383,0.84,1,"(FUT3, 0.829)","(FUT6, 0.287)","(ABO, 0.084)","(FUT1, 0.022)","(FUT2, -0.008)","(FUT5, -0.155)"]
[505,"DNA recombination (GO:0006310)",15,0.385,0.84,0.55659,"(RAD51C, 1.081)","(XRCC3, 1.019)","(TREX1, 0.162)","(ATRX, 0.142)","(IGHMBP2, 0.105)","(RPA1, 0.027)","(TP53, 0.022)","(TSN, -0.017)","(RUVBL2, -0.04)","(XRCC4, -0.075)","(XRCC5, -0.094)","(BLM, -0.101)","(RAD54L, -0.106)","(RAG1, -0.112)","(HMGB1, -0.181)"]
[505,"mRNA editing (GO:0006381)",3,0.385,0.84,0.93626,"(APOBEC1, 0.575)","(ADARB2, 0.297)","(HNRPAB, 0.016)"]
[507,"water transport (GO:0006833)",7,0.386,0.842,0.80887,"(AQP1, 0.807)","(AQP8, 0.273)","(AQP5, 0.147)","(AVP, 0.12)","(AQP2, 0.04)","(AQP9, -0.031)","(AQP7, -0.149)"]
[507,"cell ion homeostasis (GO:0006873)",4,0.386,0.842,0.81524,"(SLC12A4, 1.226)","(SLC4A1, 0.13)","(SLC12A6, -0.08)","(P2RY2, -0.21)"]
[509,"P53 DOWN Kannan et al 2001",18,0.388,0.845,1,"(COL18A1, 0.869)","(APBA2, 0.575)","(BIRC3, 0.481)","(FOSL2, 0.304)","(CCNE1, 0.22)","(BRCA1, 0.131)","(EIF4A1, 0.093)","(ARL5, 0.06)","(MAC30, 0.041)","(PURA, -0.009)","(CPM, -0.019)","(ARL4A, -0.024)","(PPAT, -0.052)","(PMP22, -0.06)","(C4orf9, -0.08)","(INA, -0.094)","(CDC6, -0.151)","(CXADR, -0.154)"]
[510,"Notch receptor processing (GO:0007220)",4,0.389,0.845,0.82808,"(NCSTN, 0.665)","(ADAM10, 0.374)","(PSEN1, 0.171)","(PSEN2, -0.241)",{"$nulls":112},"(MYF6, 0)","(HOXC5, 0)","(TFAP2B, 0)","(CTNNB1, 0)","(STAT2, 0)","(TFDP1, 0)","(ZFPM2, 0)","(MYOD1, 0)","(CRSP6, 0)","(TRIM28, 0)","(CHD2, 0)","(FOS, 0)","(TCF15, 0)","(CITED1, 0)","(TFAP4, 0)","(MNAT1, 0)","(ERF, 0)","(TEF, 0)","(NR5A1, 0)","(FOSL1, 0)","(CRSP3, 0)","(TBX3, 0)","(GSCL, 0)"]
[511,"virus-host interaction (GO:0019048)",2,0.39,0.845,1,"(CD209, 0.002)","(CLEC4M, 0.001)"]
[512,"nthiPathway BioCarta",22,0.391,0.845,0.95451,"(NFKBIA, 1.045)","(NFKB1, 0.775)","(MAPK11, 0.419)","(TGFBR2, 0.374)","(MAPK14, 0.232)","(NR3C1, 0.063)","(TGFBR1, 0.049)","(IL1B, 0.043)","(EP300, 0.037)","(TLR2, 0.014)","(MAP3K7, 0.005)","(DUSP1, 0)","(TNF, -0.004)","(CREBBP, -0.029)","(MAP2K6, -0.039)","(CHUK, -0.058)","(MAP2K3, -0.062)","(IL8, -0.065)","(MAP3K14, -0.082)","(MYD88, -0.084)","(IKBKB, -0.166)","(RELA, -0.176)"]
[513,"Inflammatory Response Pathway BioCarta",27,0.393,0.845,0.70676,"(IL4R, 1.056)","(THBS3, 0.374)","(LAMC2, 0.276)","(MUC1, 0.212)","(ZAP70, 0.202)","(CD28, 0.198)","(CD86, 0.142)","(FN1, 0.111)","(LAMC1, 0.079)","(IL2RA, 0.062)","(LAMB2, 0.061)","(TNFSF5, 0.038)","(COL1A2, 0.035)","(VTN, 0.027)","(LAMB1, 0)","(COL1A1, -0.005)","(COL3A1, -0.008)","(LAMA5, -0.008)","(IL5, -0.011)","(IL2RB, -0.015)","(IL5RA, -0.038)","(CD80, -0.076)","(IL2, -0.098)","(IL2RG, -0.116)","(IL4, -0.117)","(LCK, -0.119)","(IFNG, -0.132)"]
[514,"activation of NF-kappaB-inducing kinase (GO:0007250)",4,0.395,0.846,0.92783,"(IRAK1, 0.687)","(TLR4, 0.273)","(CARD10, 0.027)","(TLR1, -0.152)"]
[514,"ps1Pathway BioCarta",13,0.395,0.846,1,"(NOTCH1, 0.988)","(TCF1, 0.41)","(ADAM17, 0.343)","(GSK3B, 0.18)","(PSEN1, 0.168)","(AXIN1, 0.118)","(BTRC, 0.105)","(DVL1, -0.007)","(RBPSUH, -0.041)","(FZD1, -0.098)","(CTNNB1, -0.106)","(WNT1, -0.156)","(APC, -0.157)"]
[516,"phosphatidic acid biosynthesis (GO:0006654)",2,0.396,0.846,0.9278,"(AGPAT1, 0.545)","(AGPAT2, 0.255)"]
[517,"retrograde protein transport, ER to cytosol (GO:0030970)",2,0.397,0.846,1,"(DERL1, 0.001)","(VCP, 0.001)"]
[518,"ptdinsPathway BioCarta",20,0.398,0.846,0.99809,"(RPS6KB1, 0.684)","(PLCG1, 0.513)","(BTK, 0.355)","(RAC1, 0.293)","(PRKCE, 0.192)","(GSK3B, 0.175)","(PDPK1, 0.13)","(PFKM, 0.106)","(RAB5A, 0.082)","(GSK3A, 0.075)","(VAV2, 0.048)","(BAD, 0.042)","(AP2M1, 0.035)","(PFKL, -0.028)","(PFKP, -0.031)","(AKT1, -0.062)","(LYN, -0.066)","(PRKCZ, -0.077)","(EEA1, -0.079)","(ARF1, -0.112)"]
[519,"L-cystine transport (GO:0015811)",2,0.399,0.849,0.74255,"(CTNS, 0.912)","(SLC3A1, -0.133)"]
[519,"unfolded protein response (GO:0030968)",2,0.399,0.849,1,"(DERL1, 0.001)","(VCP, 0.001)"]
[521,"protein modification (GO:0006464)",33,0.4,0.851,0.50204,"(SLC35A1, 0.687)","(BACE2, 0.505)","(PIGH, 0.401)","(RPN2, 0.299)","(PAM, 0.283)","(PLAT, 0.252)","(GGCX, 0.212)","(PHEX, 0.176)","(CHRM3, 0.15)","(MMP15, 0.144)","(PLOD3, 0.097)","(PHKA2, 0.096)","(LCMT1, 0.028)","(RABGGTA, 0.021)","(ADPRH, 0.007)","(LOX, 0)","(LOXL1, -0.008)","(LOXL2, -0.015)","(LIPT1, -0.016)","(MSRA, -0.017)","(PADI4, -0.022)","(MAN2B1, -0.028)","(B4GALT7, -0.036)","(METAP2, -0.043)","(ICMT, -0.062)","(QPCT, -0.074)","(MCRS1, -0.084)","(NAGPA, -0.086)","(PRKDC, -0.102)","(PLOD2, -0.118)","(GPAA1, -0.168)","(SEPHS1, -0.18)","(UBL4, -0.209)"]
[521,"no2il12Pathway BioCarta",17,0.4,0.851,0.70758,"(IL12RB1, 0.647)","(NOS2A, 0.531)","(IL12RB2, 0.403)","(CD4, 0.34)","(IL12A, 0.308)","(CD3E, 0.3)","(IL12B, 0.16)","(CXCR3, 0)","(TYK2, -0.013)","(IFNG, -0.046)","(CD3G, -0.051)","(CD2, -0.07)","(STAT4, -0.109)","(CD3Z, -0.113)","(CD3D, -0.141)","(CCR5, -0.149)","(JAK2, -0.196)"]
[523,"dnafragmentPathway DNA fragmentation during apoptosis is effected by DFF, a caspase-activated DNAse, and by endonuclease G.",10,0.401,0.851,0.84616,"(DFFB, 0.693)","(CASP3, 0.491)","(HMGB2, 0.285)","(TOP2B, 0.078)","(GZMB, 0.076)","(CASP7, 0.009)","(TOP2A, -0.05)","(DFFA, -0.078)","(ENDOG, -0.097)","(HMGB1, -0.162)"]
[523,"s1pPathway BioCarta",8,0.401,0.851,0.97368,"(SREBF1, 0.537)","(HMGCS1, 0.374)","(SREBF2, 0.257)","(LDLR, 0.225)","(EPLIN, 0.145)","(SCAP, 0.032)","(MBTPS2, -0.003)","(MBTPS1, -0.219)"]
[525,"protein polyubiquitination (GO:0000209)",3,0.403,0.852,0.71873,"(UBE2V1, 0.334)","(UBE2V2, 0.201)","(UBE3C, 0.085)"]
[525,"caspase activity BioCarta",7,0.403,0.852,0.74413,"(CASP3, 0.652)","(CASP10, 0.201)","(CASP6, 0.164)","(CASP4, 0.11)","(CASP1, 0.017)","(CASP5, -0.02)","(CASP7, -0.032)"]
[525,"regulation of cell differentiation (GO:0045595)",2,0.403,0.852,0.95054,"(PPP2R1B, 0.495)","(TCFL5, -0.013)"]
[525,"cftrPathway The cAMP-regulated chloride channel CFTR (deficient in cystic fibrosis) is regulated by the surface-localized beta-adrenergic receptor.",12,0.403,0.852,1,"(GNAS, 0.741)","(ADRB2, 0.286)","(PRKACB, 0.279)","(PRKAR2A, 0.233)","(PRKAR2B, 0.202)","(ADCY1, 0.17)","(PRKAR1B, 0.152)","(SLC9A3R1, 0.042)","(PRKACG, -0.084)","(VIL2, -0.112)","(CFTR, -0.128)","(PRKAR1A, -0.204)"]
[529,"ST IL 13 PATHWAY Signalling Transduction KE",7,0.404,0.853,0.96099,"(IL4R, 1.774)","(JAK1, 0.068)","(IL13, 0.057)","(TYK2, -0.02)","(IL13RA2, -0.086)","(JAK2, -0.261)","(IL13RA1, -0.295)"]
[529,"regulation of DNA repair (GO:0006282)",3,0.404,0.853,0.98096,"(UBE2V2, 0.333)","(UBE2V1, 0.279)","(POLH, -0.036)"]
[529,"nkcellsPathway BioCarta",19,0.404,0.853,0.99,"(VAV1, 0.906)","(PTK2B, 0.535)","(HLA-A, 0.381)","(RAC1, 0.328)","(IL18, 0.319)","(KLRC1, 0.202)","(MAPK3, 0.123)","(KLRD1, 0.092)","(PAK1, 0.014)","(PIK3R1, -0.002)","(ITGB1, -0.017)","(PTPN6, -0.074)","(LAT, -0.11)","(MAP2K1, -0.112)","(PIK3CA, -0.114)","(B2M, -0.126)","(KLRC3, -0.144)","(KLRC4, -0.145)","(SYK, -0.224)"]
[532,"protein targeting to vacuole (GO:0006623)",2,0.407,0.855,1,"(ATG4A, 0.003)","(ATG4B, -0.001)"]
[533,"tcrPathway BioCarta",44,0.408,0.855,0.98901,"(NFKBIA, 0.781)","(VAV1, 0.641)","(NFKB1, 0.618)","(PLCG1, 0.405)","(JUN, 0.276)","(NFATC1, 0.269)","(RAC1, 0.227)","(ZAP70, 0.203)","(CD3E, 0.187)","(FYN, 0.161)","(PPP3CC, 0.157)","(TRA@, 0.142)","(NFATC3, 0.118)","(PTPN7, 0.106)","(RAF1, 0.079)","(FOS, 0.048)","(GRB2, 0.022)","(SOS1, 0.01)","(CALM1, 0.009)","(MAPK3, 0.007)","(PIK3R1, 0)","(CALM2, 0)","(CD3D, 0)","(PPP3CA, 0)","(MAP3K1, 0)","(MAP2K4, -0.014)","(CALM3, -0.025)","(SHC1, -0.03)","(PRKCA, -0.035)","(MAPK8, -0.039)","(MAP2K1, -0.048)","(PRKCB1, -0.05)","(SYT1, -0.061)","(NFATC4, -0.065)","(HRAS, -0.066)","(RELA, -0.07)","(ELK1, -0.088)","(PIK3CA, -0.09)","(LAT, -0.1)","(RASA1, -0.106)","(CD3Z, -0.111)","(CD3G, -0.122)","(PPP3CB, -0.138)","(LCK, -0.171)"]
[534,"glucose metabolism (GO:0006006)",12,0.411,0.855,0.86503,"(PDHB, 0.564)","(APOA2, 0.363)","(PDK4, 0.268)","(AKR1A1, 0.235)","(PFKM, 0.175)","(BRS3, 0.102)","(PDK1, 0.04)","(PDK2, -0.006)","(INS, -0.012)","(IRS2, -0.028)","(G6PC, -0.062)","(PDK3, -0.118)"]
[534,"urea cycle (GO:0000050)",2,0.411,0.855,0.9168,"(ASS, 0.463)","(SLC25A15, 0.168)"]
[534,"secretory pathway (GO:0045045)",3,0.411,0.855,0.99029,"(TXNDC4, 0.48)","(TFIP11, 0.38)","(CKLF, -0.082)"]
[537,"SIG InsulinReceptorPathwayInCardiacMyocytes SignallingAlliance",50,0.413,0.858,0.97207,"(CAP1, 0.484)","(RPS6KB1, 0.48)","(SLC2A4, 0.468)","(AKT2, 0.455)","(SFN, 0.338)","(FOXO1A, 0.316)","(BRD4, 0.195)","(RPS6KA2, 0.18)","(PARD3, 0.17)","(INPPL1, 0.148)","(PARD6A, 0.143)","(SORBS1, 0.128)","(SOS2, 0.097)","(IRS2, 0.094)","(IRS1, 0.069)","(F2RL2, 0.063)","(FLOT1, 0.057)","(GSK3A, 0.057)","(MAPK3, 0.052)","(GSK3B, 0.052)","(YWHAE, 0.006)","(RAF1, 0.003)","(YWHAZ, 0)","(PSCD3, 0)","(PPYR1, 0)","(YWHAH, 0)","(PDK1, 0)","(SOS1, 0)","(PTPN1, 0)","(SHC1, 0)","(CBL, 0)","(YWHAB, 0)","(MAPK1, 0)","(SERPINB6, -0.005)","(LNPEP, -0.007)","(CDC42, -0.014)","(GRB2, -0.015)","(RPS6KA1, -0.015)","(PIK3R1, -0.016)","(FLOT2, -0.023)","(RPS6KA3, -0.027)","(YWHAQ, -0.034)","(PIK3CA, -0.041)","(AKT3, -0.058)","(CDKN2A, -0.09)","(PTEN, -0.107)","(AKT1, -0.108)","(IGFBP1, -0.119)","(IRS4, -0.158)","(PIK3CD, -0.209)"]
[538,"immune response (GO:0006955)",112,0.414,0.862,0.73162,"(CX3CL1, 0.969)","(FTH1, 0.947)","(IL4R, 0.576)","(HRH2, 0.224)","(CNIH, 0.211)","(ANXA11, 0.21)","(IL6R, 0.204)","(FCER1G, 0.204)","(CTSC, 0.188)","(CD164, 0.178)","(TNFRSF14, 0.161)","(CTSG, 0.154)","(IL18, 0.143)","(DEFB4, 0.135)","(IKBKAP, 0.129)","(IL16, 0.11)","(SEMA3C, 0.1)","(LCP2, 0.088)","(CTSW, 0.077)","(SECTM1, 0.074)","(CCRL1, 0.069)","(HAMP, 0.041)","(IL18R1, 0.023)","(CNR2, 0)","(PTGER4, 0)","(LAT, 0)","(G1P3, 0)","(DPP4, 0)","(FCAR, 0)","(TNFRSF9, 0)","(MADCAM1, 0)","(TCF8, 0)","(EDG6, 0)","(CD59, 0)","(CMKLR1, 0)","(RGS1, 0)","(MS4A1, 0)","(IKBKG, 0)","(C1QBP, 0)","(CST7, 0)","(FCGR2A, 0)","(ATP6V0A2, 0)","(TNFRSF11A, 0)","(TCF12, 0)","(TAPBP, 0)","(OPRD1, 0)","(KIR2DS2, 0)","(FCGR1A, 0)","(FYB, 0)","(IL7R, 0)","(CD6, 0)","(CD79B, 0)","(CRH, 0)","(STAT5A, 0)","(GEM, 0)","(IK, 0)","(CTLA4, 0)","(AQP9, 0)","(TCF7, 0)","(IL2RG, 0)","(ETS1, 0)","(SP2, 0)","(CRHR1, 0)","(CTSS, 0)","(CD86, 0)","(EBI2, 0)","(CEACAM8, 0)","(XBP1, 0)","(CCR8, 0)","(GPR65, 0)","(AFP, 0)","(ZAP70, 0)","(F3, 0)","(SEMA4D, 0)","(IL15, 0)","(KIR2DL1, 0)","(MBP, 0)","(MBL2, 0)","(GBP2, 0)","(PFC, 0)","(CHUK, 0)","(TNFRSF4, 0)","(CD80, 0)","(C8B, 0)","(ARHGDIB, 0)","(IL1R2, 0)","(IFITM3, 0)","(CD96, 0)","(BPI, 0)","(TRIM22, 0)","(C1R, 0)","(IL2RB, 0)","(SEMA7A, 0)","(GPR44, 0)","(FCGR2B, 0)","(C8A, 0)","(KIR2DL3, 0)","(DGKD, 0)","(MAP4K2, 0)","(RFX1, 0)","(VTN, 0)","(CCL27, 0)","(IL2RA, 0)","(RAG1, 0)","(OPRK1, 0)","(CCBP2, 0)","(AIM2, 0)","(GZMA, 0)","(FCER1A, 0)","(VIPR1, -0.015)","(IL6ST, -0.021)","(GTPBP1, -0.045)"]
[539,"regulation of muscle contraction (GO:0006937)",10,0.415,0.862,0.74083,"(MYL5, 0.534)","(PPP1R12A, 0.528)","(MYL9, 0.356)","(TNNT2, 0.3)","(TNNC2, 0.022)","(TPM1, -0.017)","(PPP1R12B, -0.086)","(TNNT1, -0.095)","(TNNI3, -0.169)","(TNNI2, -0.242)"]
[539,"platelet activation (GO:0030168)",4,0.415,0.862,0.8379,"(EVL, 1.081)","(GP1BA, 0.069)","(F2, 0.023)","(PF4, -0.064)"]
[539,"transcription-coupled nucleotide-excision repair (GO:0006283)",4,0.415,0.862,0.96492,"(ERCC2, 0.644)","(ERCC3, 0.333)","(XAB2, -0.098)","(ERCC5, -0.126)"]
[539,"regulation of transcription from RNA polymerase III promoter (GO:0006359)",6,0.415,0.862,0.98926,"(ZNF76, 1.416)","(BRCA1, 0.137)","(POLR3C, -0.012)","(POLR3G, -0.08)","(ZNF345, -0.181)","(ZNF143, -0.239)"]
[539,"FETAL LIVER HS ENRICHED TF JP Manually Curated",81,0.415,0.862,1,"(TGIF, 0.476)","(NFKB1, 0.45)","(RNF14, 0.342)","(GATA2, 0.325)","(PHC2, 0.319)","(FOXO1A, 0.318)","(HLF, 0.275)","(PHTF1, 0.251)","(IFI35, 0.251)","(MLL, 0.17)","(GTF2IRD1, 0.15)","(HP1-BP74, 0.149)","(NR2C2, 0.13)","(RNF7, 0.113)","(BRD4, 0.113)","(SRF, 0.11)","(DSIPI, 0.108)","(FOS, 0.099)","(H2AFZ, 0.095)","(TCERG1, 0.077)","(SPIB, 0.055)","(HDAC1, 0.02)","(SPI1, 0.014)","(HKR3, 0)","(RBX1, 0)","(ZNF238, 0)","(NCOA3, 0)","(HHEX, 0)","(ILF2, 0)","(SMARCD1, 0)","(TFE3, 0)","(GFI1, 0)","(UBTF, 0)","(MYC, 0)","(SMC1L1, 0)","(HMGB1, 0)","(ELF1, 0)","(SPOP, 0)","(ETV5, 0)","(SOX13, 0)","(MEF2A, 0)","(BAZ1B, 0)","(H2AFY2, 0)","(SIRT2, 0)","(STAT5A, 0)","(ID4, 0)","(HIST1H4A, 0)","(FOSB, 0)","(RUNX1, 0)","(ELK3, 0)","(HMGN2, 0)","(ZNF282, 0)","(PROX1, 0)","(EVI1, 0)","(PMF1, 0)","(ELK4, 0)","(RNF4, 0)","(MED6, 0)","(RFXANK, 0)","(NRF1, 0)","(MEF2C, 0)","(TCFL1, 0)","(ZFP64, 0)","(SP100, 0)","(MDFI, 0)","(HTATIP, 0)","(DNMT3B, 0)","(NSD1, 0)","(HCNGP, 0)","(DNMT3A, 0)","(DDIT3, 0)","(PQBP1, 0)","(ZNF435, 0)","(NR1H3, 0)","(EGR1, -0.008)","(DBP, -0.014)","(NMI, -0.021)","(ETS1, -0.023)","(SOX15, -0.023)","(MYST3, -0.026)","(EGR3, -0.03)"]
[539,"cell-cell recognition (GO:0009988)",2,0.415,0.862,1,"(CD209, 0.002)","(CLEC4M, 0.001)"]
[545,"organelle organization and biogenesis (GO:0006996)",4,0.416,0.864,0.91674,"(KIF4A, 0.726)","(KIF5C, 0.279)","(KIF25, 0.07)","(KIF3A, -0.237)"]
[545,"G-protein signaling, adenylate cyclase inhibiting pathway (GO:0007193)",7,0.416,0.864,0.9923,"(NPY2R, 0.314)","(RGS1, 0.294)","(OPRL1, 0.29)","(NPY1R, 0.211)","(CORT, 0.184)","(OPRK1, 0.179)","(GPR24, -0.269)"]
[545,"Il12Pathway BioCarta",22,0.416,0.864,0.99307,"(IL12RB1, 0.597)","(JUN, 0.418)","(IL18, 0.341)","(IL12RB2, 0.322)","(IL12A, 0.302)","(TRA@, 0.253)","(CD3E, 0.248)","(MAPK14, 0.216)","(IL12B, 0.166)","(IL18R1, 0.101)","(ETV5, 0.014)","(CXCR3, -0.004)","(MAPK8, -0.005)","(CD3G, -0.014)","(TYK2, -0.055)","(STAT4, -0.072)","(CD3D, -0.074)","(IFNG, -0.08)","(JAK2, -0.112)","(CD3Z, -0.119)","(CCR5, -0.121)","(MAP2K6, -0.15)"]
[548,"mitotic sister chromatid segregation (GO:0000070)",3,0.419,0.866,0.97288,"(ZW10, 0.396)","(KIF25, 0.109)","(ESPL1, 0.091)"]
[548,"SA BONE MORPHOGENETIC SigmaAldrich",5,0.419,0.866,1,"(BMPR1B, 0.806)","(BMPR1A, 0.18)","(BMPR2, 0.05)","(MADH6, -0.089)","(BMP1, -0.096)"]
[550,"cell cycle checkpoint (GO:0000075)",8,0.42,0.866,0.63869,"(CCNG2, 0.749)","(RB1, 0.474)","(ATR, 0.342)","(CCNE2, 0.078)","(TP53, -0.03)","(FANCG, -0.036)","(CDKN2A, -0.149)","(SMC1L1, -0.199)"]
[550,"amyloid precursor protein catabolism (GO:0042987)",3,0.42,0.866,0.87789,"(NCSTN, 0.824)","(PSEN1, 0.249)","(PSEN2, -0.294)"]
[550,"growth (GO:0040007)",2,0.42,0.866,1,"(GHR, 0.002)","(ST6GAL1, 0.001)"]
[553,"angiogenesis (GO:0001525)",5,0.421,0.866,0.91926,"(IL18, 0.719)","(ARTS-1, 0.306)","(VEGF, 0.065)","(ROBO4, 0.022)","(IL8, -0.091)"]
[553,"tetrahydrobiopterin biosynthesis (GO:0006729)",2,0.421,0.866,0.99059,"(PTS, 1.072)","(SPR, -0.466)"]
[555,"parkinsonsPathway BLACK",2,0.423,0.866,0.87131,"(SNCA, 0.734)","(PARK2, -0.192)"]
[555,"negative regulation of growth (GO:0045926)",3,0.423,0.866,0.94777,"(ALOX15B, 0.913)","(BBC3, 0.293)","(ING4, -0.232)"]
[557,"glycosaminoglycan biosynthesis (GO:0006024)",5,0.424,0.868,0.97612,"(HAS1, 0.693)","(UGDH, 0.22)","(GCNT2, 0.172)","(EXT1, -0.042)","(EXT2, -0.074)"]
[557,"atmPathway The tumor-suppressing protein kinase ATM responds to radiation-induced DNA damage by blocking cell-cycle progression and activating DNA repair.",20,0.424,0.868,1,"(NFKBIA, 1.063)","(NFKB1, 0.874)","(JUN, 0.406)","(BRCA1, 0.172)","(CHEK1, 0.16)","(RAD50, 0.137)","(TP73, 0.111)","(NBS1, 0.019)","(RBBP8, 0.002)","(MAPK8, -0.023)","(CHEK2, -0.024)","(ABL1, -0.042)","(GADD45A, -0.051)","(ATM, -0.054)","(CDKN1A, -0.061)","(TP53, -0.08)","(MRE11A, -0.089)","(MDM2, -0.111)","(RAD51, -0.129)","(RELA, -0.206)"]
[559,"TGF Beta Signaling Pathway BioCarta",36,0.425,0.868,0.96803,"(TGIF, 0.677)","(NFKB1, 0.631)","(JUN, 0.318)","(SKIL, 0.288)","(FOXH1, 0.251)","(TGFBR2, 0.245)","(SPP1, 0.18)","(EGF, 0.166)","(SERPINE1, 0.166)","(TFE3, 0.138)","(FOS, 0.116)","(FKBP1A, 0.108)","(TGFBR1, 0.073)","(ENG, 0.071)","(MAPK3, 0.058)","(MADH6, 0)","(CTNNB1, 0)","(LIF, -0.006)","(RUNX3, -0.007)","(IFNG, -0.014)","(ZFHX1B, -0.018)","(SKI, -0.022)","(BMP4, -0.024)","(TNF, -0.029)","(CREBBP, -0.031)","(INHBA, -0.032)","(LEF1, -0.045)","(STAT1, -0.047)","(TGFBR3, -0.05)","(THBS1, -0.066)","(RUNX2, -0.066)","(TGFB1, -0.068)","(FST, -0.074)","(ITGB6, -0.088)","(MAPK9, -0.089)","(STAT3, -0.149)"]
[560,"acute-phase response (GO:0006953)",7,0.426,0.868,0.80892,"(LBP, 0.548)","(AHSG, 0.372)","(CEBPB, 0.349)","(ORM2, 0.124)","(ORM1, 0.04)","(APCS, -0.075)","(STAT3, -0.134)"]
[561,"epidermal growth factor receptor signaling pathway (GO:0007173)",13,0.427,0.869,0.29832,"(EPS15, 0.425)","(RPS6KA5, 0.359)","(GRB7, 0.33)","(EGF, 0.299)","(GAB1, 0.252)","(ERBB2IP, 0.144)","(REPS2, 0.121)","(EGFR, 0.058)","(EPS8, 0.048)","(CBL, 0.019)","(EREG, 0.014)","(GRB2, -0.004)","(SHC3, -0.262)"]
[561,"chondroitin sulfate proteoglycan biosynthesis, polysaccharide chain biosynthesis (GO:0050653)",2,0.427,0.869,0.94504,"(GALNACT-2, 0.581)","(ChGn, 0.06)"]
[561,"fatty acid beta-oxidation (GO:0006635)",9,0.427,0.869,0.9973,"(ACADVL, 0.74)","(PPARD, 0.239)","(CPT1B, 0.235)","(HADHB, 0.203)","(ECHS1, 0.115)","(ACADM, -0.009)","(ECH1, -0.053)","(ACADS, -0.138)","(CPT1A, -0.167)"]
[561,"virion attachment to host cell surface receptor (GO:0019062)",2,0.427,0.869,1,"(CD209, 0.002)","(CLEC4M, 0.001)"]
[565,"visual perception (GO:0007601)",99,0.428,0.872,0.80999,"(CYP1B1, 1.217)","(DHRS3, 0.763)","(COL18A1, 0.381)","(ARR3, 0.253)","(PDE6D, 0.224)","(PDE6A, 0.222)","(PDE6G, 0.209)","(CRYM, 0.204)","(RGS16, 0.203)","(CNGA3, 0.196)","(RDH5, 0.176)","(UNC119, 0.172)","(CRYBB2, 0.16)","(TACSTD2, 0.15)","(PDE6B, 0.137)","(FSCN2, 0.122)","(SIX6, 0.107)","(POU6F2, 0.1)","(CNGA1, 0.057)","(CRYAA, 0.051)","(OPA1, 0.037)","(GPR143, 0.023)","(EML2, 0.013)","(VAX2, 0.012)","(SORD, 0.008)","(EYA3, 0)","(EML1, 0)","(RABGGTB, 0)","(TULP1, 0)","(RPGR, 0)","(SIX3, 0)","(PDE6H, 0)","(RS1, 0)","(CLNS1A, 0)","(ABCA4, 0)","(NR2E3, 0)","(GNAT1, 0)","(NDP, 0)","(OCLM, 0)","(ROM1, 0)","(GJA8, 0)","(CRYBA1, 0)","(CRYGD, 0)","(NRL, 0)","(TBL1X, 0)","(WFS1, 0)","(VMD2, 0)","(FOXC1, 0)","(GUCA1A, 0)","(RP2, 0)","(CRYBA4, 0)","(FBN1, 0)","(MYOC, 0)","(MYO7A, 0)","(CDS1, 0)","(CRYZ, 0)","(PAX2, 0)","(TGFBI, 0)","(POU4F3, 0)","(RRH, 0)","(CRYAB, 0)","(LUM, 0)","(OPN1SW, 0)","(CHM, 0)","(COL11A1, 0)","(VSX1, 0)","(EYA4, 0)","(CRYGA, 0)","(OAT, 0)","(TYR, 0)","(GJA3, 0)","(AOC2, 0)","(CACNA1F, 0)","(GRM8, 0)","(RABGGTA, 0)","(RPE65, 0)","(ABLIM1, 0)","(RCV1, 0)","(OPN1MW, 0)","(PDE6C, 0)","(RDS, 0)","(GUCY2F, 0)","(CRYBB1, 0)","(PRR4, 0)","(CRYBB3, 0)","(KRT12, 0)","(RAX, 0)","(TULP2, 0)","(CNGB3, 0)","(KIFC3, 0)","(PAX6, 0)","(EFEMP1, 0)","(GUCY2D, 0)","(CRX, 0)","(RGR, 0)","(AIPL1, 0)","(RLBP1, 0)","(RBP3, 0)","(CHML, -0.008)"]
[565,"amiPathway Endogenous anti-thrombosis pathways are overwhelmed in plaque-narrowed blood vessels, resulting in potentially lethal myocardial infarction.",23,0.428,0.872,0.94925,"(GNAS, 0.505)","(CSK, 0.442)","(HLA-DRB1, 0.284)","(CD3E, 0.255)","(CD4, 0.236)","(PRKAR2B, 0.213)","(TRA@, 0.198)","(ZAP70, 0.181)","(PRKACB, 0.169)","(PRKAR2A, 0.158)","(PRKAR1B, 0.138)","(ADCY1, 0.111)","(HLA-DRA, 0.001)","(GNB1, -0.034)","(PTPRC, -0.049)","(CREBBP, -0.052)","(LCK, -0.061)","(CD3G, -0.066)","(PRKAR1A, -0.092)","(PRKACG, -0.119)","(CD3D, -0.119)","(GNGT1, -0.182)","(CD3Z, -0.204)"]
[567,"MAP00460 Cyanoamino acid metabolism GenMAPP",4,0.431,0.876,0.84298,"(SHMT1, 1.08)","(LOC56901, -0.047)","(GGT1, -0.093)","(SHMT2, -0.204)"]
[567,"ace2Pathway Angiotensin-converting enzyme 2 (ACE2) digests the blood-pressure regulator angiotensin II (AGT) ultimately to the vasodilator AGT1-7.",12,0.431,0.876,1,"(COL4A1, 0.685)","(REN, 0.307)","(AGTR1, 0.268)","(ACE2, 0.263)","(COL4A6, 0.138)","(COL4A3, 0.093)","(AGTR2, 0.021)","(COL4A5, 0.004)","(AGT, -0.018)","(COL4A2, -0.094)","(CMA1, -0.114)","(COL4A4, -0.116)"]
[569,"phosphatidylcholine biosynthesis (GO:0006656)",2,0.432,0.878,0.98539,"(PCYT1B, 0.714)","(PEMT, -0.2)"]
[569,"I-kappaB kinase/NF-kappaB cascade (GO:0007249)",3,0.432,0.878,0.98968,"(TIAF1, 0.885)","(STAT1, 0.117)","(IKBKG, -0.205)"]
[571,"morphogenesis (GO:0009653)",93,0.433,0.881,0.72451,"(WNT5A, 0.683)","(GLI3, 0.411)","(PAX8, 0.358)","(EVA1, 0.309)","(DSCR1L2, 0.26)","(GPC4, 0.227)","(HOXA4, 0.219)","(EFNB2, 0.218)","(TH, 0.209)","(HOXC13, 0.187)","(POU5F1, 0.185)","(SCML1, 0.184)","(NFE2L1, 0.174)","(CLTCL1, 0.169)","(FGF3, 0.168)","(FSCN2, 0.161)","(EYA1, 0.137)","(ERCC1, 0.131)","(SALL1, 0.113)","(LBX1, 0.104)","(SIX2, 0.087)","(GSCL, 0.08)","(IER3, 0.065)","(GPC3, 0.024)","(PKD1, 0.016)","(BICD1, 0.009)","(CST6, 0.007)","(SCML2, 0.007)","(MCAM, 0)","(KRT18, 0)","(FOXE1, 0)","(DKK3, 0)","(NEDD8, 0)","(TBX6, 0)","(EDN3, 0)","(NR5A2, 0)","(TBX1, 0)","(MRPL40, 0)","(HOXD3, 0)","(FGF8, 0)","(SOX10, 0)","(PTCH, 0)","(HOXB5, 0)","(TPD52, 0)","(TWIST1, 0)","(TBX10, 0)","(CPM, 0)","(DVL1, 0)","(LIG1, 0)","(KRTHA5, 0)","(CYR61, 0)","(SIAH1, 0)","(HLXB9, 0)","(LZTR1, 0)","(PITX1, 0)","(FGF18, 0)","(HOXC10, 0)","(MMP11, 0)","(FOXC1, 0)","(SOX13, 0)","(DEAF1, 0)","(MID1, 0)","(WNT2B, 0)","(CASR, 0)","(WNT11, 0)","(ROD1, 0)","(FBN2, 0)","(WBSCR14, 0)","(TBX19, 0)","(F2R, 0)","(TBX5, 0)","(ZNF141, 0)","(HOXA11, 0)","(FAT, 0)","(EYA4, 0)","(MAS1, 0)","(PES1, 0)","(EZH1, 0)","(GCM1, 0)","(EN1, 0)","(HIRA, 0)","(WNT7A, 0)","(RFP2, 0)","(PAX7, 0)","(CORIN, 0)","(FGF1, 0)","(TBX3, 0)","(WNT1, 0)","(TSHB, 0)","(CHUK, -0.001)","(MYOC, -0.016)","(GATA3, -0.025)","(EYA3, -0.067)"]
[571,"response to pest, pathogen or parasite (GO:0009613)",8,0.433,0.881,0.9417,"(SLC13A4, 0.687)","(GSR, 0.439)","(DEFB4, 0.236)","(CAPG, 0.131)","(SLC11A1, 0.094)","(IL1F9, 0.04)","(PABPC4, -0.077)","(CHIT1, -0.166)"]
[571,"imprinting (GO:0006349)",2,0.433,0.881,0.96641,"(DNMT3A, 0.435)","(IGF2, 0.043)"]
[574,"negative regulation of progression through cell cycle (GO:0045786)",3,0.437,0.886,0.95805,"(ALOX15B, 0.867)","(GMNN, -0.1)","(RHOB, -0.144)"]
[574,"MAP00680 Methane metabolism GenMAPP",7,0.437,0.886,0.97954,"(SHMT1, 0.803)","(ADH5, 0.321)","(LPO, 0.135)","(MPO, 0.106)","(CAT, -0.09)","(LOC56901, -0.118)","(SHMT2, -0.193)"]
[574,"ubiquitin cycle (GO:0006512)",3,0.437,0.886,1,"(TSG101, 1.14)","(SMURF1, -0.208)","(UBQLN3, -0.263)"]
[577,"ectoderm development (GO:0007398)",7,0.438,0.887,0.85915,"(KRT6A, 0.834)","(VAX2, 0.336)","(TFAP2A, 0.053)","(KRT6B, 0.041)","(FOXE1, -0.004)","(SMURF1, -0.037)","(EPIM, -0.073)"]
[577,"Fatty Acid Synthesis BioCarta",15,0.438,0.887,0.89826,"(ACLY, 1.04)","(SCD, 0.767)","(HADHSC, 0.146)","(PRKAB1, 0.118)","(SLC25A1, 0.1)","(PRKAG2, 0.084)","(PRKAA2, -0.037)","(FASN, -0.039)","(ACACA, -0.078)","(ACAA2, -0.095)","(PRKAA1, -0.111)","(PRKAB2, -0.13)","(PC, -0.146)","(PRKAG1, -0.184)","(ACACB, -0.229)"]
[577,"single strand break repair (GO:0000012)",3,0.438,0.887,0.9099,"(TNP1, 0.688)","(APTX, 0.305)","(LIG4, -0.383)"]
[580,"MAP00430 Taurine and hypotaurine metabolism GenMAPP",4,0.439,0.889,0.73026,"(GAD1, 1.081)","(BAAT, -0.041)","(GGT1, -0.069)","(GAD2, -0.152)"]
[581,"mitotic chromosome condensation (GO:0007076)",4,0.44,0.889,0.98617,"(SMC4L1, 0.759)","(SMC2L1, 0.192)","(PCOLN3, -0.001)","(BRRN1, -0.137)"]
[582,"regulation of cell redox homeostasis (GO:0030503)",2,0.441,0.889,0.9677,"(TXNDC4, 0.47)","(EGLN2, -0.053)"]
[583,"Proteasome Degradation BioCarta",32,0.446,0.899,0.50068,"(H2AFX, 0.741)","(UBE2D2, 0.408)","(MKI67, 0.317)","(UBE1L, 0.262)","(PSMC1, 0.237)","(PSMD1, 0.233)","(PSMB6, 0.218)","(PSMD3, 0.143)","(PSMD4, 0.141)","(H2AFZ, 0.129)","(PSMA7, 0.122)","(PSMA6, 0.103)","(PSMB9, 0.047)","(UBE2D3, 0.004)","(PSME2, 0)","(UBE1, 0)","(PSMC6, -0.018)","(PSMB7, -0.021)","(PSMC5, -0.026)","(UBA52, -0.031)","(PSMD2, -0.037)","(IFNG, -0.053)","(UBC, -0.065)","(PSMD8, -0.075)","(PSMC4, -0.113)","(UBE2D1, -0.115)","(PSMA4, -0.125)","(PSMC2, -0.127)","(PSMC3, -0.136)","(PSMD5, -0.147)","(PSMA1, -0.151)","(RPS27A, -0.18)"]
[583,"DNA metabolism (GO:0006259)",9,0.446,0.899,0.98741,"(KPNA2, 0.949)","(NT5E, 0.848)","(DTYMK, 0.009)","(ENDOG, -0.032)","(ADRA1D, -0.07)","(IGFBP4, -0.071)","(TFDP2, -0.144)","(RAN, -0.223)","(DNASE2, -0.252)"]
[585,"positive regulation of enzyme activity (GO:0043085)",4,0.447,0.899,0.90368,"(NCSTN, 0.73)","(PSEN1, 0.22)","(BTG1, 0.146)","(PSEN2, -0.214)"]
[586,"ST Interleukin 4 Pathway Signalling Transduction KE",26,0.449,0.903,0.23324,"(IL4R, 1.056)","(RPS6KB1, 0.666)","(AKT2, 0.588)","(INPP5D, 0.175)","(IARS, 0.167)","(SOS2, 0.104)","(JAK1, 0.091)","(PI3, 0.085)","(SOS1, 0.022)","(AKT3, 0.016)","(STAT6, 0.005)","(JAK3, 0.005)","(SHC1, -0.007)","(CISH, -0.007)","(PPP1R13B, -0.025)","(SRC, -0.032)","(GRB2, -0.033)","(SERPINA4, -0.051)","(TYK2, -0.059)","(JAK2, -0.064)","(NR0B2, -0.072)","(PIK3CA, -0.076)","(AKT1, -0.115)","(IL2RG, -0.119)","(IL4, -0.134)","(IL13RA1, -0.164)"]
[586,"protein targeting to mitochondrion (GO:0006626)",7,0.449,0.903,0.98021,"(TIMM17B, 0.472)","(TOMM22, 0.31)","(BZRP, 0.282)","(TOMM34, 0.104)","(TIMM44, -0.056)","(TIMM23, -0.1)","(TIMM17A, -0.177)"]
[588,"MAP00533 Keratan sulfate biosynthesis GenMAPP",7,0.45,0.904,0.58937,"(B4GALT5, 0.884)","(FUT8, 0.52)","(B4GALT2, 0.099)","(B4GALT3, 0.084)","(B4GALT1, 0.062)","(PPOX, -0.238)","(SIAT1, -0.326)"]
[588,"sex differentiation (GO:0007548)",7,0.45,0.904,0.99581,"(IDE, 1.07)","(AMH, 0.183)","(WNT7A, 0.045)","(AMHR2, 0.013)","(TSPY1, -0.027)","(CYP17A1, -0.042)","(FSHPRH1, -0.162)"]
[590,"SIG Regulation of the actin cytoskeleton by Rho GTPases SignallingAlliance",33,0.451,0.904,0.9623,"(CFL1, 0.57)","(PFN2, 0.358)","(MYLK, 0.305)","(GDI2, 0.296)","(FSCN2, 0.248)","(MYH2, 0.244)","(FLNA, 0.184)","(ANGPTL2, 0.184)","(ROCK2, 0.183)","(ACTR3, 0.114)","(VASP, 0.103)","(RPS4X, 0.085)","(ROCK1, 0.074)","(PAK2, 0.072)","(WASF1, 0.068)","(PAK7, 0.043)","(GDI1, 0.011)","(PAK6, 0)","(PFN1, 0)","(FLNC, 0)","(RHO, -0.023)","(CDC42, -0.023)","(PAK1, -0.035)","(ACTG2, -0.039)","(FSCN1, -0.047)","(AKT1, -0.052)","(FSCN3, -0.069)","(PAK3, -0.095)","(PAK4, -0.097)","(ACTR2, -0.113)","(ACTG1, -0.113)","(WASL, -0.126)","(LIMK1, -0.127)"]
[591,"fluid secretion (GO:0007589)",7,0.452,0.905,0.68849,"(NPR1, 0.92)","(AGTR1, 0.371)","(SLC22A4, 0.137)","(NPPB, -0.037)","(GUCA1B, -0.117)","(VIP, -0.153)","(SLC34A1, -0.239)"]
[591,"cremPathway The transcription factor CREM activates a post-meiotic transcriptional cascade culminating in spermatogenesis.",7,0.452,0.905,0.76364,"(GNAS, 0.893)","(ADCY1, 0.272)","(XPO1, 0.084)","(FSHB, 0.013)","(FHL5, -0.03)","(CREM, -0.03)","(FSHR, -0.071)"]
[591,"il10Pathway BioCarta",13,0.452,0.905,1,"(IL1A, 0.578)","(BLVRB, 0.46)","(IL6, 0.223)","(BLVRA, 0.152)","(IL10RA, 0.126)","(IL10, 0.064)","(JAK1, 0.049)","(STAT5A, 0.043)","(STAT1, 0.039)","(HMOX1, -0.023)","(IL10RB, -0.113)","(TNF, -0.113)","(STAT3, -0.209)"]
[594,"ubiquitin-dependent protein catabolism (GO:0006511)",24,0.453,0.905,0.48547,"(PSMD14, 0.662)","(UBE3A, 0.412)","(CYB561D2, 0.32)","(SMURF2, 0.311)","(CDC23, 0.143)","(FBXO7, 0.142)","(ARIH1, 0.11)","(FZR1, 0.107)","(BTRC, 0.083)","(CDC20, 0.08)","(ANAPC2, 0.073)","(FBXL4, 0.051)","(SIAH2, 0.04)","(ANAPC10, -0.007)","(UBE4A, -0.015)","(UBE2E1, -0.037)","(PARK2, -0.038)","(ANAPC5, -0.043)","(NEDD8, -0.057)","(UBE2C, -0.072)","(UBE2A, -0.077)","(UBE2L3, -0.091)","(USP33, -0.107)","(UBE2D1, -0.127)"]
[594,"fertilization (sensu Metazoa) (GO:0007338)",12,0.453,0.905,0.81891,"(XKRY, 0.561)","(SPA17, 0.468)","(CLGN, 0.302)","(SPAG1, 0.175)","(GNPDA1, 0.162)","(CLU, 0.146)","(MST1R, 0.063)","(OR10J1, 0.024)","(ADAM20, -0.04)","(ADAM21, -0.093)","(BPY2, -0.127)","(DNALI1, -0.147)"]
[596,"Fatty Acid Degradation BioCarta",19,0.454,0.908,0.90625,"(ACADVL, 0.525)","(LPL, 0.468)","(HADHA, 0.293)","(CPT2, 0.175)","(CRAT, 0.155)","(HADHSC, 0.142)","(GPD2, 0.133)","(CPT1B, 0.115)","(TPI1, 0.1)","(HADHB, 0.093)","(SLC25A20, 0.001)","(GK, 0.001)","(ACADSB, -0.011)","(ACADM, -0.019)","(ACAA2, -0.03)","(GK2, -0.052)","(ACADL, -0.085)","(ACADS, -0.13)","(CPT1A, -0.195)"]
[597,"positive regulation of cell growth (GO:0030307)",2,0.456,0.909,0.8754,"(SPHK1, 0.327)","(ALOX12, 0.166)"]
[598,"receptor mediated endocytosis (GO:0006898)",23,0.458,0.911,0.97077,"(SORL1, 0.594)","(STAB1, 0.473)","(FOLR1, 0.335)","(RAMP2, 0.288)","(CLTCL1, 0.273)","(AP1S1, 0.2)","(ADRB2, 0.186)","(RAMP3, 0.09)","(IGF2R, 0.052)","(PIK4CB, 0.044)","(M6PR, 0.034)","(SFTPD, 0.031)","(PICALM, 0.015)","(LRP1B, -0.012)","(ASGR1, -0.016)","(MSR1, -0.044)","(HFE, -0.05)","(LRP3, -0.055)","(AP1S2, -0.068)","(MRC1, -0.082)","(SCARF1, -0.1)","(LRP2, -0.146)","(DNM1, -0.158)"]
[598,"macrophage chemotaxis (GO:0048246)",3,0.458,0.911,1,"(SAA1, 0.626)","(SFTPD, 0.209)","(CKLF, -0.121)"]
[598,"fibrinolysisPathway Thrombin cleavage of fibrinogen results in rapid formation of fibrin threads that form a mesh to capture platelets and other blood cells into a clot.",12,0.458,0.911,1,"(SERPINB2, 0.544)","(PLAT, 0.5)","(SERPINE1, 0.351)","(CPB2, 0.194)","(FGA, 0.186)","(F2, 0.051)","(PLG, 0.009)","(F2R, -0.017)","(FGG, -0.07)","(FGB, -0.093)","(PLAU, -0.151)","(F13A1, -0.169)"]
[601,"microtubule-based process (GO:0007017)",2,0.46,0.914,0.86742,"(PAFAH1B1, 0.425)","(KIFAP3, 0.142)"]
[601,"substrate-bound cell migration, cell extension (GO:0006930)",3,0.46,0.914,0.99796,"(THBS4, 0.958)","(OPHN1, -0.08)","(CD2AP, -0.318)"]
[603,"bcrPathway B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen.",34,0.461,0.915,0.93038,"(VAV1, 0.719)","(PLCG1, 0.46)","(MAPK14, 0.326)","(NFATC1, 0.291)","(JUN, 0.288)","(RAC1, 0.236)","(BTK, 0.213)","(PPP3CC, 0.175)","(NFATC3, 0.166)","(FOS, 0.16)","(MAPK3, 0.109)","(CD79B, 0.085)","(PPP3CA, 0.044)","(SOS1, 0.008)","(MAPK8, 0.001)","(GRB2, 0.001)","(CALM1, 0)","(RAF1, 0)","(HRAS, 0)","(LYN, -0.003)","(MAP3K1, -0.008)","(SHC1, -0.016)","(PRKCB1, -0.019)","(BLNK, -0.024)","(SYT1, -0.032)","(ELK1, -0.057)","(MAP2K1, -0.062)","(NFATC4, -0.063)","(CALM2, -0.065)","(CD79A, -0.067)","(CALM3, -0.105)","(PRKCA, -0.119)","(SYK, -0.125)","(PPP3CB, -0.17)"]
[604,"microtubule cytoskeleton organization and biogenesis (GO:0000226)",4,0.462,0.918,0.95611,"(RNF19, 0.546)","(TUBG2, 0.151)","(MID1, 0.056)","(MAPT, 0.035)"]
[604,"cell growth and or maintenance The processes pertinent to the integrated function of a cell.",64,0.462,0.918,0.98477,"(TFF1, 0.672)","(CTGF, 0.6)","(GATA2, 0.352)","(IL6R, 0.286)","(COL5A2, 0.261)","(FOS, 0.21)","(SKIL, 0.186)","(EXTL1, 0.182)","(IER3, 0.18)","(CCL4, 0.166)","(PPAP2B, 0.155)","(GPC3, 0.134)","(SEMA3C, 0.12)","(MXD4, 0.116)","(PPAP2A, 0.106)","(LGALS7, 0.096)","(KIAA0052, 0.081)","(ERBB2, 0.047)","(SMO, 0.045)","(DUSP12, 0.038)","(PCOLCE, 0.015)","(ADPRT, 0.008)","(FLJ10305, 0)","(QSCN6, 0)","(RHCG, 0)","(DNAJA3, 0)","(HMG20B, 0)","(LECT1, 0)","(TACC3, 0)","(EIF3S6, 0)","(GEM, 0)","(PLAU, 0)","(FGF5, 0)","(MTM1, 0)","(CLN5, 0)","(ANGPT2, 0)","(DRG2, 0)","(PRSS11, 0)","(NF1, 0)","(DTNA, 0)","(IRF5, 0)","(GAS2, 0)","(SUI1, 0)","(INSR, 0)","(PRDM1, 0)","(DDX1, 0)","(RANBP9, 0)","(GAS2L1, 0)","(INHBA, 0)","(EXTL3, 0)","(STMN1, 0)","(SKI, 0)","(DDX26, 0)","(EDF1, 0)","(EXT2, -0.001)","(OS-9, -0.015)","(LIMD1, -0.015)","(EVI1, -0.016)","(EXT1, -0.034)","(TRPM1, -0.038)","(GNA12, -0.05)","(JAK3, -0.059)","(CDR1, -0.079)","(HPN, -0.083)"]
[606,"physiological process (GO:0007582)",5,0.464,0.921,0.62654,"(MC4R, 1.001)","(OR7A5, 0.272)","(PRR4, 0.069)","(PTGS2, -0.133)","(PTGS1, -0.242)"]
[606,"metabotropic glutamate receptor signaling pathway (GO:0007216)",3,0.464,0.921,0.86979,"(HOMER2, 0.727)","(HOMER3, 0.138)","(GRM6, -0.144)"]
[606,"DNA fragmentation during apoptosis (GO:0006309)",5,0.464,0.921,0.9291,"(DFFB, 0.983)","(CIDEA, 0.152)","(CYCS, 0.14)","(DFFA, -0.057)","(PDCD8, -0.253)"]
[609,"dermatan sulfate proteoglycan biosynthesis, polysaccharide chain biosynthesis (GO:0050652)",2,0.466,0.921,0.94504,"(GALNACT-2, 0.514)","(ChGn, 0.051)"]
[609,"telomerase-dependent telomere maintenance (GO:0007004)",7,0.466,0.921,1,"(TINF2, 0.622)","(RFC1, 0.609)","(RAD50, 0.146)","(TERF2IP, -0.103)","(TERF2, -0.177)","(DKC1, -0.183)","(MRE11A, -0.198)"]
[611,"SA G1 AND S PHASES SigmaAldrich",15,0.467,0.921,0.47671,"(CFL1, 0.816)","(ARF3, 0.654)","(CDKN1B, 0.328)","(E2F1, 0.31)","(E2F2, 0.055)","(NXT1, 0.039)","(CCND1, -0.003)","(CDK2, -0.017)","(TP53, -0.024)","(PRB1, -0.063)","(ARF1, -0.07)","(CDKN2A, -0.091)","(CDKN1A, -0.092)","(MDM2, -0.104)","(CDK4, -0.181)"]
[611,"posttranslational protein folding (GO:0051084)",2,0.467,0.921,0.84277,"(SEP15, 0.592)","(UGCGL2, -0.218)"]
[611,"base-excision repair, DNA ligation (GO:0006288)",2,0.467,0.921,0.86763,"(HMGB2, 0.668)","(HMGB1, -0.187)"]
[611,"monoamine transport (GO:0015844)",3,0.467,0.921,0.97427,"(SLC18A2, 0.713)","(PRKCABP, 0.142)","(SLC18A1, -0.295)"]
[611,"autophagic vacuole formation (GO:0000045)",2,0.467,0.921,1,"(ATG4A, 0.003)","(ATG4B, -0.001)"]
[616,"regulation of cytokine biosynthesis (GO:0042035)",2,0.469,0.921,0.96472,"(IL12B, 0.61)","(S100B, -0.04)"]
[617,"tcapoptosisPathway BioCarta",10,0.47,0.921,0.90047,"(CD4, 0.462)","(CD3E, 0.407)","(CD28, 0.367)","(TRA@, 0.305)","(TNFRSF6, 0.148)","(TNFSF6, 0.105)","(CD3D, -0.082)","(CCR5, -0.095)","(CD3G, -0.136)","(CD3Z, -0.202)"]
[618,"Glycogen Metabolism BioCarta",35,0.471,0.921,0.64154,"(GYG, 0.337)","(PPP2R5C, 0.321)","(GYG2, 0.258)","(PPP2CA, 0.224)","(PHKB, 0.205)","(PPP2R1B, 0.174)","(AGL, 0.17)","(PR48, 0.17)","(GSK3B, 0.127)","(GSK3A, 0.102)","(PPP2R2A, 0.094)","(PPP2R5E, 0.086)","(PHKA2, 0.086)","(GYS2, 0.076)","(PYGL, 0.064)","(PPP2R5B, 0.06)","(UGP2, 0.059)","(PPP2R4, 0.053)","(PYGM, 0.051)","(PPP2R5D, 0.037)","(PPP2R1A, 0.022)","(PHKG1, 0.01)","(PYGB, 0.001)","(GBE1, -0.007)","(CALM1, -0.007)","(PPP2R5A, -0.031)","(CALM2, -0.046)","(PHKA1, -0.071)","(GYS1, -0.078)","(PHKG2, -0.082)","(PPP2CB, -0.104)","(CALM3, -0.127)","(PPP2R2B, -0.132)","(PPP2R3A, -0.162)","(PGM1, -0.166)"]
[618,"Eicosanoid Synthesis BioCarta",15,0.471,0.921,0.76566,"(PLA2G6, 1.057)","(LTC4S, 0.473)","(ALOX15B, 0.463)","(ALOX15, 0.115)","(ALOX12, 0.088)","(ALOX5, 0.052)","(LTA4H, 0.035)","(PTGIS, -0.033)","(ALOX5AP, -0.081)","(PTGDS, -0.087)","(PLA2G2A, -0.099)","(PTGS2, -0.118)","(DPEP1, -0.129)","(TBXAS1, -0.149)","(PTGS1, -0.161)"]
[620,"p53 signalling BioCarta",97,0.472,0.921,0.71801,"(NFKB1, 0.44)","(WIG1, 0.356)","(PMAIP1, 0.34)","(TRAF5, 0.337)","(SFN, 0.289)","(BRAP, 0.256)","(PRKCG, 0.25)","(HIF1A, 0.239)","(RB1, 0.234)","(FAF1, 0.233)","(TP53AP1, 0.218)","(MAP4, 0.204)","(DP1, 0.2)","(ABCB1, 0.185)","(SERPINB5, 0.175)","(TTRAP, 0.175)","(CTSD, 0.114)","(CHEK1, 0.098)","(CSNK2B, 0.066)","(BAP1, 0.065)","(ATR, 0.065)","(BAX, 0.025)","(P53AIP1, 0.021)","(EI24, 0.02)","(CCNH, 0.009)","(CSNK2A2, 0.008)","(THBS1, 0.008)","(TNFRSF10B, 0.008)","(BZRP, 0)","(WRN, 0)","(WT1, 0)","(RELA, 0)","(NDRG4, 0)","(APEX1, 0)","(SIRT1, 0)","(TP53BP2, 0)","(MAP2K7, 0)","(BRCA1, 0)","(MYC, 0)","(TNF, 0)","(EP300, 0)","(ACTA1, 0)","(TP53, 0)","(DAXX, 0)","(CREBBP, 0)","(STAT5A, 0)","(PRKCB1, 0)","(HIPK2, 0)","(GADD45A, 0)","(PMP22, 0)","(PPIA, 0)","(CDC2, 0)","(TRAF1, 0)","(TNFSF6, 0)","(REPRIMO, 0)","(APAF1, 0)","(GTSE1, 0)","(NDRG2, 0)","(TRAF4, 0)","(NDRG3, 0)","(PRKDC, 0)","(BCL2, 0)","(NUMB, 0)","(PRKCA, 0)","(CDK7, 0)","(TP73, 0)","(HSPA4, 0)","(TEAD1, 0)","(MDM2, 0)","(BAI1, 0)","(CSNK2A1, 0)","(CDKN2A, 0)","(TP73L, 0)","(CHEK2, 0)","(PML, 0)","(ESR1, 0)","(SP1, 0)","(RPL13A, 0)","(THRA, 0)","(LRDD, 0)","(BBC3, 0)","(PRKCQ, 0)","(MAP2K4, 0)","(NDRG1, 0)","(TNFAIP1, 0)","(RASA1, 0)","(E2F1, 0)","(FADD, 0)","(GAPD, 0)","(TBP, 0)","(CSNK1A1, 0)","(CDKN1A, 0)","(PCAF, 0)","(ACTB, 0)","(MAPK8IP2, -0.04)","(ATM, -0.059)","(CASP9, -0.081)"]
[620,"fusion of sperm to egg plasma membrane (GO:0007342)",3,0.472,0.921,1,"(CD9, 0.534)","(ADAM2, 0.182)","(CRISP1, -0.05)"]
[622,"GNF FEMALE GENES na",84,0.473,0.921,1,"(SERPING1, 0.832)","(PROS1, 0.437)","(MITF, 0.346)","(TCTE1L, 0.342)","(RPL15, 0.276)","(NNMT, 0.224)","(CCL21, 0.204)","(ADAM22, 0.2)","(ISLR, 0.192)","(LRP1, 0.188)","(RBMS1, 0.18)","(GAB2, 0.176)","(RPS3A, 0.157)","(RPS4X, 0.136)","(GAS1, 0.127)","(CEBPB, 0.117)","(CLIC4, 0.104)","(HTR2B, 0.102)","(RPL35A, 0.094)","(GYPC, 0.09)","(HNRPDL, 0.074)","(IGFBP5, 0.039)","(CLECSF2, 0.024)","(IGFBP3, 0.021)","(RPL31, 0.009)","(RPL34, 0.008)","(HRB2, 0)","(WSB1, 0)","(RPS27A, 0)","(PTGIS, 0)","(RPL36AL, 0)","(TMOD1, 0)","(RPS24, 0)","(SRY, 0)","(RPL21, 0)","(IGFBP1, 0)","(SFRP4, 0)","(NS3TP2, 0)","(FTL, 0)","(RPL9, 0)","(RPS6, 0)","(PRG1, 0)","(RPL7, 0)","(SLC24A3, 0)","(NAP1L1, 0)","(DHRS8, 0)","(CYR61, 0)","(RPL5, 0)","(RPL39, 0)","(HNRPA1, 0)","(MFGE8, 0)","(AEBP1, 0)","(TPM4, 0)","(IGFBP4, 0)","(RPL6, 0)","(CDH11, 0)","(SH3BP5, 0)","(RPL26, 0)","(TGM2, 0)","(RPL17, 0)","(ITPR1, 0)","(OGT, 0)","(RPS17, 0)","(TXNIP, 0)","(COL6A3, 0)","(GBP2, 0)","(RPL36A, 0)","(GATA6, 0)","(ADAMTS1, 0)","(RPL10, 0)","(CACNG2, 0)","(XIST, 0)","(EEF1B2, 0)","(LAPTM5, 0)","(COL6A1, 0)","(RPL24, 0)","(IFI16, 0)","(THBS1, -0.007)","(CREB3L2, -0.008)","(STOM, -0.012)","(EFEMP1, -0.015)","(EIF3S6, -0.028)","(RPS3, -0.043)","(TGFBR3, -0.065)"]
[622,"MAP00240 Pyrimidine metabolism GenMAPP",44,0.473,0.921,1,"(NP, 0.641)","(RRM2, 0.273)","(CTPS, 0.254)","(POLR2G, 0.232)","(NME2, 0.219)","(TK1, 0.197)","(POLD2, 0.173)","(CAD, 0.165)","(POLA, 0.155)","(DHODH, 0.15)","(DOK4, 0.133)","(DCK, 0.128)","(POLE, 0.121)","(AK3, 0.089)","(POLR1B, 0.075)","(POLR2H, 0.065)","(POLR2I, 0.045)","(POLR2A, 0.037)","(UMPS, 0.033)","(IGFBP7, 0.026)","(CDA, 0.008)","(POLR2L, 0.003)","(POLB, 0)","(POLR2K, 0)","(POLG, 0)","(POLR2J, -0.008)","(NME1, -0.008)","(DCTD, -0.012)","(DPYD, -0.013)","(TYMS, -0.015)","(UBTF, -0.015)","(DUT, -0.017)","(POLR2F, -0.017)","(POLD1, -0.018)","(RRM1, -0.023)","(ECGF1, -0.028)","(POLR2C, -0.029)","(POLR2E, -0.032)","(POLR2D, -0.074)","(POLRMT, -0.08)","(UMPK, -0.102)","(DPYS, -0.13)","(POLR2J2, -0.154)","(POLR2B, -0.209)"]
[624,"endoderm development (GO:0007492)",2,0.474,0.921,0.82303,"(LAMC1, 0.337)","(HOXC11, -0.109)"]
[625,"gata3Pathway BioCarta",15,0.475,0.922,0.92386,"(NFATC1, 0.468)","(MAPK14, 0.281)","(PRKACB, 0.265)","(PRKAR2B, 0.217)","(PRKAR2A, 0.209)","(MAF, 0.174)","(PRKAR1B, 0.114)","(IL5, 0.04)","(PRKACG, -0.035)","(GATA3, -0.042)","(IL13, -0.056)","(JUNB, -0.077)","(IL4, -0.107)","(MAP2K3, -0.12)","(PRKAR1A, -0.143)"]
[626,"succinyl-CoA metabolism (GO:0006104)",2,0.477,0.927,0.92896,"(SUCLA2, 0.693)","(OXCT1, -0.193)"]
[627,"ceramidePathway Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type.",22,0.478,0.927,0.9743,"(NFKB1, 0.803)","(TRADD, 0.781)","(TNFRSF1A, 0.242)","(TRAF2, 0.229)","(CYCS, 0.129)","(BAX, 0.095)","(SMPD1, 0.085)","(RAF1, 0.065)","(BCL2, 0.064)","(BAD, 0.062)","(CASP8, 0.059)","(MAPK1, 0.047)","(MAPK3, 0.043)","(RIPK1, 0.006)","(FADD, 0.005)","(NSMAF, 0)","(MAP2K4, -0.022)","(MAP2K1, -0.032)","(MAPK8, -0.054)","(MAP3K1, -0.112)","(RELA, -0.151)","(PDCD8, -0.211)"]
[628,"SIG IL4RECEPTOR IN B LYPHOCYTES SignallingAlliance",27,0.479,0.927,0,"(IL4R, 1.041)","(AKT2, 0.576)","(SOCS1, 0.271)","(SOS2, 0.154)","(GSK3B, 0.131)","(MAPK3, 0.099)","(BAD, 0.085)","(GSK3A, 0.074)","(RAF1, 0.04)","(JAK1, 0.031)","(IRS1, 0.016)","(BCL2, 0.012)","(JAK3, 0.002)","(PIK3R1, 0)","(PDK1, -0.008)","(GRB2, -0.012)","(SOS1, -0.012)","(IRS2, -0.021)","(AKT3, -0.032)","(PPP1R13B, -0.033)","(AKT1, -0.051)","(SHC1, -0.057)","(MAP4K1, -0.06)","(STAT6, -0.067)","(MAPK1, -0.076)","(PIK3CA, -0.092)","(PIK3CD, -0.186)"]
[628,"transport (GO:0006810)",64,0.479,0.927,0.50835,"(AKR1C2, 1.458)","(ABCC1, 1.119)","(AQP6, 0.271)","(STX8, 0.26)","(ENSA, 0.217)","(ABCB1, 0.211)","(SLC7A7, 0.184)","(ABCA3, 0.155)","(ABCC2, 0.152)","(ABCB7, 0.149)","(SLC25A3, 0.031)","(SLC25A12, 0.031)","(SLC25A13, 0.021)","(ABCB8, 0.02)","(AQP4, 0.018)","(ABCC3, 0.008)","(ABCD2, 0)","(ABCA1, 0)","(SLC25A17, 0)","(SLC25A11, 0)","(ALB, 0)","(SLC7A9, 0)","(GJB1, 0)","(ATP1B2, 0)","(ZNF238, 0)","(CLNS1A, 0)","(ABCB11, 0)","(SLC11A1, 0)","(SLC7A4, 0)","(SCARB1, 0)","(AKAP9, 0)","(ATP1A3, 0)","(SLC7A2, 0)","(GJA8, 0)","(PEA15, 0)","(SLC7A8, 0)","(SLC7A5, 0)","(NPTX1, 0)","(ABCD4, 0)","(ABCC5, 0)","(ABCB4, 0)","(GJA4, 0)","(AR, 0)","(CORO1A, 0)","(AQP8, 0)","(SLC16A2, 0)","(XK, 0)","(ABCG2, 0)","(SLC25A5, 0)","(TTPA, 0)","(ATP1B3, 0)","(ATP1B1, 0)","(ASNA1, 0)","(SLC30A3, 0)","(ABCF2, -0.015)","(GJA1, -0.015)","(ABCA4, -0.016)","(TM9SF2, -0.029)","(SLC25A14, -0.036)","(SLN, -0.041)","(SLC25A4, -0.072)","(PTGDS, -0.089)","(SRI, -0.093)","(ABCC6, -0.11)"]
[630,"apoptosis (GO:0006915)",64,0.481,0.928,0.72632,"(NFKBIA, 0.658)","(TXNL1, 0.582)","(PTK2B, 0.292)","(PDCD1, 0.288)","(LGALS1, 0.273)","(IL1A, 0.266)","(ADORA2A, 0.259)","(CTNNAL1, 0.258)","(CD14, 0.141)","(IER3, 0.141)","(IL17, 0.086)","(CSE1L, 0.085)","(SGPL1, 0.078)","(BBC3, 0.062)","(SCARB1, 0.061)","(RAF1, 0.059)","(E2F1, 0.047)","(PPARD, 0.031)","(ESPL1, 0.021)","(YARS, 0.008)","(MAPT, 0.005)","(TNFSF9, 0.004)","(TP73L, 0)","(ADRA1A, 0)","(RIPK1, 0)","(PAX3, 0)","(IAPP, 0)","(PDE1B, 0)","(LY86, 0)","(SIAH1, 0)","(PDCD2, 0)","(TRIB3, 0)","(DDX41, 0)","(GADD45B, 0)","(PDCD11, 0)","(F2R, 0)","(GADD45A, 0)","(IL1B, 0)","(EP300, 0)","(GAS2, 0)","(TNF, 0)","(CYCS, 0)","(GML, 0)","(NCKAP1, 0)","(DAXX, 0)","(F2, 0)","(TESK2, 0)","(GZMB, 0)","(IL24, 0)","(MDM4, 0)","(AHR, 0)","(IL2RA, 0)","(GZMA, 0)","(FXR1, -0.008)","(HD, -0.009)","(TNFSF7, -0.009)","(MRPS30, -0.01)","(ING4, -0.02)","(MAGEH1, -0.044)","(AGTR2, -0.045)","(TP53, -0.045)","(PTPN6, -0.049)","(GPR65, -0.054)","(DOCK1, -0.099)"]
[631,"humoral immune response (GO:0006959)",25,0.482,0.928,0.57431,"(GPI, 0.609)","(PDCD1, 0.458)","(BRDG1, 0.301)","(CCR6, 0.231)","(CD28, 0.194)","(CD24, 0.175)","(EBI3, 0.142)","(IL6, 0.124)","(LTF, 0.117)","(TREM1, 0.099)","(HLXB9, 0.067)","(TREM2, 0.066)","(POU2AF1, 0.063)","(LY86, 0.016)","(MS4A2, 0.014)","(BCL2, 0.01)","(POU2F2, 0.003)","(IL7, -0.003)","(PSMB10, -0.036)","(RFXANK, -0.085)","(PAX5, -0.088)","(CD83, -0.094)","(BST1, -0.11)","(CCL2, -0.132)","(BST2, -0.14)"]
[632,"ST Ga13 Pathway Signalling Transduction KE",37,0.483,0.931,0.56582,"(NFKBIA, 0.826)","(NFKB1, 0.666)","(AKT2, 0.504)","(NFKBIL1, 0.226)","(PIK3CB, 0.217)","(SRF, 0.213)","(LPA, 0.182)","(PHKA2, 0.175)","(PI3, 0.133)","(ROCK2, 0.112)","(PLD1, 0.08)","(ROCK1, 0.052)","(NFKB2, 0.007)","(NFKBIB, 0)","(MAP2K4, 0)","(BCL2, 0)","(PTK2, -0.002)","(TBXA2R, -0.003)","(PLD2, -0.004)","(AKT3, -0.006)","(DLG4, -0.006)","(CDC42, -0.016)","(BF, -0.016)","(MAP3K5, -0.021)","(IKBKG, -0.023)","(SERPINA4, -0.024)","(PLD3, -0.024)","(GNA13, -0.029)","(ARHGEF11, -0.033)","(MAP3K1, -0.039)","(PDK1, -0.04)","(MAPK8, -0.052)","(RDX, -0.097)","(AKT1, -0.1)","(NFKBIL2, -0.133)","(NFKBIE, -0.158)","(PRKCM, -0.164)"]
[633,"negative regulation of adenylate cyclase activity (GO:0007194)",14,0.485,0.932,0.81374,"(ADRA2A, 0.63)","(GABBR1, 0.439)","(GRM4, 0.258)","(GRM2, 0.233)","(GNAI3, 0.127)","(GRM8, 0.112)","(GPR51, 0.099)","(LTB4R2, 0.079)","(CCR2, -0.035)","(GALR1, -0.043)","(GNAI2, -0.1)","(GRM7, -0.115)","(EDNRB, -0.134)","(GRM3, -0.146)"]
[633,"gsPathway BioCarta",6,0.485,0.932,0.84787,"(GNAS, 1.009)","(ADCY1, 0.241)","(GNB1, 0.042)","(PRKACA, -0.064)","(PRKAR1A, -0.121)","(GNGT1, -0.327)"]
[633,"spliceosome assembly (GO:0000245)",2,0.485,0.932,0.89767,"(CRNKL1, 0.294)","(SIP1, 0.2)"]
[636,"induction of apoptosis (GO:0006917)",64,0.486,0.933,0.9516,"(TRADD, 0.489)","(TNFSF12, 0.391)","(BCL10, 0.334)","(INHA, 0.313)","(UNC13B, 0.258)","(TNFRSF7, 0.235)","(PPP2CA, 0.204)","(DPF1, 0.2)","(CASP3, 0.194)","(ALOX15B, 0.192)","(ERCC2, 0.186)","(PPP2R1B, 0.179)","(TNFSF8, 0.17)","(TNFRSF9, 0.142)","(TRAF3, 0.116)","(PRKCE, 0.1)","(SMNDC1, 0.094)","(EI24, 0.094)","(BAK1, 0.069)","(FOXO3A, 0.056)","(CASP10, 0.036)","(DIABLO, 0.016)","(TRIP, 0.014)","(ERCC3, 0.012)","(NUDT2, 0.004)","(BNIP3L, 0.002)","(DAPK2, 0)","(TNFSF14, 0)","(HRK, 0)","(BCL2L11, 0)","(S100B, 0)","(MAPK1, 0)","(TP73L, 0)","(LTA, 0)","(TIAL1, 0)","(HD, 0)","(CD2, 0)","(IKBKG, 0)","(DEDD, 0)","(APOE, 0)","(BIK, 0)","(STK17A, 0)","(CASP6, 0)","(CASP4, 0)","(MX1, 0)","(PLAGL1, 0)","(STK17B, 0)","(BCLAF1, 0)","(DCC, 0)","(TLR2, 0)","(PPP2R1A, 0)","(PDCD5, 0)","(LALBA, 0)","(NOTCH2, 0)","(COL4A3, -0.007)","(ZNF443, -0.007)","(NME3, -0.008)","(ERN1, -0.017)","(DAPK3, -0.029)","(MAP3K10, -0.032)","(IFNA2, -0.086)","(TNFSF10, -0.111)","(TIA1, -0.164)","(INHBA, -0.177)"]
[637,"regulation of DNA replication (GO:0006275)",2,0.487,0.934,0.80519,"(PPP2R1B, 0.618)","(CDK2, -0.021)"]
[637,"amine metabolism (GO:0009308)",3,0.487,0.934,0.93198,"(AOC3, 0.554)","(SULT1C1, 0.326)","(SULT1A1, -0.189)"]
[637,"regulation of viral genome replication (GO:0045069)",2,0.487,0.934,1,"(CCL3, 0.675)","(PPIA, -0.141)"]
[637,"EMT DOWN Jechlinger et al 2003",40,0.487,0.934,1,"(CTGF, 0.757)","(TIAM1, 0.325)","(KLF2, 0.303)","(IRF6, 0.302)","(SERPINB5, 0.278)","(ITGB5, 0.269)","(BCL6, 0.232)","(PADI2, 0.194)","(FLNA, 0.192)","(GRB7, 0.141)","(NNT, 0.115)","(FBP2, 0.105)","(TACSTD1, 0.083)","(TIMP3, 0.072)","(ARHGEF1, 0.069)","(CTSH, 0.053)","(ITPR1, 0.043)","(TGFB3, 0.039)","(STAT5A, 0.021)","(RARA, 0.008)","(DUSP1, 0)","(SGK, 0)","(TGM2, -0.007)","(THBS1, -0.014)","(EGR2, -0.015)","(ATF3, -0.015)","(VAMP8, -0.028)","(AMD1, -0.045)","(KITLG, -0.047)","(ATP1A1, -0.05)","(ACTN4, -0.062)","(JUP, -0.073)","(F3, -0.08)","(MYH9, -0.082)","(PKP1, -0.083)","(HMMR, -0.085)","(FOSB, -0.116)","(EGR1, -0.12)","(NUMB, -0.153)","(CDH1, -0.194)"]
[641,"SIG BCR Signaling Pathway SignallingAlliance",45,0.488,0.934,0.70604,"(VAV1, 0.64)","(PLCG2, 0.504)","(AKT2, 0.475)","(CSK, 0.322)","(NFATC1, 0.267)","(BTK, 0.262)","(CD22, 0.23)","(INPP5D, 0.166)","(CD81, 0.16)","(DAG1, 0.152)","(PPP3CC, 0.147)","(SOS2, 0.145)","(FLOT1, 0.124)","(MAPK3, 0.119)","(ITPR1, 0.106)","(BAD, 0.106)","(GSK3B, 0.063)","(GSK3A, 0.047)","(LYN, 0.034)","(SOS1, 0.03)","(PPP3CA, 0.016)","(RAF1, 0.002)","(BCL2, 0)","(ITPR3, 0)","(PIK3R1, -0.005)","(GRB2, -0.006)","(PDK1, -0.007)","(MAP4K1, -0.009)","(AKT1, -0.012)","(AKT3, -0.014)","(FLOT2, -0.015)","(PIK3CA, -0.015)","(ITPR2, -0.024)","(BLNK, -0.038)","(CR2, -0.041)","(NR0B2, -0.057)","(CD19, -0.074)","(SHC1, -0.086)","(PPP3CB, -0.088)","(SYK, -0.092)","(MAPK1, -0.099)","(PTPRC, -0.1)","(PPP1R13B, -0.11)","(BCR, -0.132)","(PIK3CD, -0.213)"]
[641,"aging (GO:0007568)",3,0.488,0.934,1,"(MORF4, 0.393)","(WRN, 0.145)","(LOXL2, 0.073)"]
[643,"Ras protein signal transduction (GO:0007265)",18,0.489,0.934,0.84524,"(ADRA2A, 0.537)","(G3BP, 0.462)","(RRAS, 0.36)","(IGF1, 0.23)","(GRAP2, 0.217)","(PARK7, 0.192)","(GRAP, 0.163)","(RASSF1, 0.15)","(PLD1, 0.078)","(MRAS, 0.041)","(SOS1, 0.011)","(FGF2, -0.02)","(CRKL, -0.035)","(GRB2, -0.06)","(NF1, -0.068)","(LAT, -0.133)","(LCK, -0.14)","(RREB1, -0.218)"]
[643,"protein stabilization (GO:0050821)",5,0.489,0.934,0.92093,"(HPS4, 0.251)","(PPARGC1A, 0.237)","(APBB2, 0.229)","(MDM4, 0.062)","(APBB1, -0.024)"]
[645,"cell cycle checkpointII GO",10,0.49,0.934,0.42529,"(CCNG2, 0.631)","(RB1, 0.463)","(ATR, 0.275)","(CCNE2, 0.058)","(NBS1, 0.005)","(TP53, -0.042)","(RBBP8, -0.053)","(FANCG, -0.069)","(CDC34, -0.078)","(CDKN2A, -0.138)"]
[645,"tumor supressor BioCarta",23,0.49,0.934,1,"(CFL1, 0.716)","(TGFBR2, 0.357)","(CDKN1B, 0.308)","(RB1, 0.282)","(MSH2, 0.222)","(GAPD, 0.14)","(LCMT2, 0.109)","(CDKN1C, 0.094)","(BRCA1, 0.089)","(NF2, 0.077)","(TGFBR1, 0.047)","(VHL, -0.004)","(CREBBP, -0.021)","(EP300, -0.022)","(ACTB, -0.025)","(TP53, -0.036)","(WT1, -0.067)","(IRF1, -0.093)","(APC, -0.094)","(BRCA2, -0.101)","(CDKN2D, -0.108)","(TSC2, -0.13)","(PTEN, -0.183)"]
[647,"MAP00020 Citrate cycle TCA cycle GenMAPP",18,0.491,0.934,0.53714,"(ACLY, 1.005)","(IDH1, 0.505)","(IDH3A, 0.346)","(SDHB, 0.223)","(DLD, 0.126)","(MDH1, 0.081)","(SDHA, 0.019)","(OGDH, -0.014)","(ACO2, -0.028)","(IDH2, -0.049)","(IDH3G, -0.051)","(PCK1, -0.081)","(CS, -0.121)","(PC, -0.133)","(MDH2, -0.159)","(DLST, -0.176)","(FH, -0.177)","(ACO1, -0.235)"]
[647,"rasPathway BioCarta",22,0.491,0.934,0.54623,"(H2AFX, 0.881)","(NFKB1, 0.839)","(RAC1, 0.354)","(RHOA, 0.093)","(RAF1, 0.068)","(MAPK3, 0.068)","(RALBP1, 0.057)","(PIK3R1, 0.049)","(MLLT7, 0.036)","(BAD, 0.024)","(MAP2K1, -0.004)","(RALA, -0.007)","(HRAS, -0.012)","(ELK1, -0.026)","(PIK3CA, -0.06)","(CHUK, -0.064)","(CDC42, -0.068)","(AKT1, -0.105)","(CASP9, -0.105)","(BCL2L1, -0.115)","(RALGDS, -0.127)","(RELA, -0.168)"]
[649,"CR IMMUNE FUNCTION PNAS 2009",54,0.492,0.934,1,"(LAG3, 0.578)","(IL12RB1, 0.384)","(CD63, 0.378)","(HLA-C, 0.286)","(HCA127, 0.254)","(BTK, 0.234)","(CD22, 0.218)","(IL16, 0.198)","(CD4, 0.198)","(IL17, 0.175)","(CD24, 0.173)","(CD14, 0.171)","(CD9, 0.169)","(MICA, 0.154)","(CD34, 0.147)","(CD72, 0.141)","(MAGED2, 0.131)","(GAGE4, 0.117)","(IFNGR1, 0.075)","(IFNB1, 0.073)","(NKTR, 0.07)","(BAGE, 0.063)","(IL18R1, 0.032)","(CD2, 0.028)","(TFE3, 0.015)","(IL13, 0)","(CD33, 0)","(IL4, 0)","(CD68, 0)","(FCGR2B, 0)","(CD37, 0)","(CD8A, 0)","(IL10, 0)","(CD19, 0)","(CD53, 0)","(CD58, 0)","(IFNAR2, 0)","(CD47, 0)","(IL2RB, 0)","(IFNAR1, 0)","(CD97, -0.008)","(CD59, -0.009)","(CD7, -0.017)","(CD1D, -0.021)","(CD69, -0.022)","(SLAMF1, -0.025)","(IFNG, -0.026)","(CTAG2, -0.052)","(IL15, -0.054)","(IL1B, -0.07)","(IFNA1, -0.117)","(CD48, -0.138)","(CD36, -0.161)","(IL6ST, -0.161)"]
[650,"endosome to lysosome transport (GO:0008333)",3,0.493,0.936,0.89486,"(ADRB2, 0.606)","(M6PR, -0.025)","(RHOB, -0.174)"]
[651,"determination of left/right symmetry (GO:0007368)",3,0.494,0.939,0.68617,"(KIF3B, 0.39)","(PITX2, 0.15)","(ZIC3, 0.01)"]
[651,"actin filament polymerization (GO:0030041)",4,0.494,0.939,0.98243,"(RAC1, 0.729)","(WASF1, 0.323)","(WASF3, -0.199)","(GSN, -0.239)"]
[653,"ST Ga12 Pathway Signalling Transduction KE",23,0.495,0.939,0.94118,"(VAV1, 0.819)","(JUN, 0.387)","(F2RL3, 0.385)","(BTK, 0.373)","(F2RL1, 0.329)","(MAPK7, 0.16)","(F2RL2, 0.086)","(RAF1, 0.08)","(PLD1, 0.072)","(SRC, 0.042)","(F2, 0.006)","(PLD3, -0.01)","(PLD2, -0.014)","(BF, -0.017)","(DLG4, -0.026)","(MAPK1, -0.053)","(RASAL1, -0.057)","(MAPK8, -0.068)","(TEC, -0.091)","(EPHB2, -0.104)","(MAP2K5, -0.123)","(PTK2, -0.138)","(MYEF2, -0.139)"]
[653,"ngfPathway BioCarta",19,0.495,0.939,0.9745,"(KLK2, 0.548)","(PLCG1, 0.518)","(JUN, 0.422)","(RAF1, 0.114)","(NGFR, 0.108)","(FOS, 0.097)","(MAPK3, 0.047)","(DPM2, 0.022)","(SOS1, 0.011)","(NGFB, -0.01)","(MAPK8, -0.039)","(GRB2, -0.044)","(PIK3R1, -0.056)","(SHC1, -0.059)","(PIK3CA, -0.086)","(MAP2K1, -0.097)","(HRAS, -0.1)","(CSNK2A1, -0.118)","(ELK1, -0.131)"]
[653,"MAP00230 Purine metabolism GenMAPP",82,0.495,0.939,1,"(NP, 0.474)","(GUCY1A3, 0.405)","(NPR1, 0.319)","(XDH, 0.302)","(GART, 0.281)","(PDE6G, 0.251)","(RRM2, 0.224)","(POLR2G, 0.218)","(ADCY9, 0.218)","(PDE6B, 0.192)","(POLD2, 0.186)","(PKLR, 0.158)","(NME2, 0.142)","(PDE1A, 0.11)","(PDE4A, 0.101)","(GMPR, 0.1)","(DCK, 0.081)","(DOK4, 0.069)","(POLR2I, 0.067)","(GUCY1B3, 0.051)","(ATP5J, 0.041)","(POLR2H, 0.023)","(RRM1, 0.017)","(POLR2L, 0.016)","(GUCY2D, 0.014)","(AMPD3, 0.014)","(IGFBP7, 0.011)","(POLA, 0.007)","(ADSS, 0)","(POLE, 0)","(POLR2E, 0)","(GMPS, 0)","(ADCY7, 0)","(POLR2J2, 0)","(ECGF1, 0)","(NPR2, 0)","(NME1, 0)","(ADCY6, 0)","(ADA, 0)","(POLB, 0)","(POLR1B, 0)","(IMPDH1, 0)","(DGUOK, 0)","(APRT, 0)","(POLD1, 0)","(AMPD2, 0)","(GUCY2F, 0)","(HPRT1, 0)","(PDE4B, 0)","(POLR2D, 0)","(ADK, 0)","(PRPS2, 0)","(POLR2F, 0)","(PPAT, 0)","(GUCY1A2, 0)","(POLR2K, 0)","(POLG, 0)","(ADSL, 0)","(PDE6C, 0)","(ATIC, 0)","(GUCY2C, 0)","(PDE5A, 0)","(ADCY1, 0)","(POLR2B, 0)","(PDE4C, 0)","(POLR2J, 0)","(PKM2, 0)","(PDE4D, 0)","(PRPS1, 0)","(POLR2A, 0)","(PAICS, 0)","(POLRMT, 0)","(ADCY3, 0)","(AK1, 0)","(ADCY2, 0)","(AK2, 0)","(FHIT, 0)","(IMPDH2, 0)","(ADCY8, 0)","(AMPD1, -0.009)","(PFAS, -0.015)","(POLR2C, -0.016)"]
[656,"blood pressure regulation (GO:0008217)",21,0.496,0.939,0.65786,"(RENBP, 0.876)","(SLC12A4, 0.554)","(REN, 0.296)","(UTS2, 0.194)","(GNB3, 0.15)","(CORIN, 0.135)","(GCGR, 0.081)","(AGTR2, 0.067)","(FGA, 0.046)","(BRS3, 0.03)","(FGB, 0.012)","(AGT, -0.011)","(NPR2, -0.025)","(NPPA, -0.038)","(FGG, -0.078)","(CHGA, -0.082)","(PTGS2, -0.11)","(CYP11B2, -0.115)","(EDN1, -0.162)","(ACE, -0.17)","(PTGS1, -0.176)"]
[656,"fmlppathway The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase.",36,0.496,0.939,1,"(NFKBIA, 0.864)","(NFKB1, 0.711)","(NFATC1, 0.292)","(NCF1, 0.263)","(CAMK1G, 0.215)","(RAC1, 0.213)","(MAPK14, 0.209)","(NFATC3, 0.165)","(PPP3CC, 0.15)","(PIK3C2G, 0.122)","(GNB1, 0.116)","(NCF2, 0.113)","(FPR1, 0.063)","(MAPK3, 0.058)","(MAP2K2, 0.046)","(RAF1, 0.023)","(HRAS, 0.017)","(PAK1, 0.016)","(PPP3CA, 0.002)","(CALM1, 0)","(NFATC4, 0)","(MAP2K3, -0.01)","(MAPK1, -0.011)","(PLCB1, -0.02)","(CALM2, -0.028)","(SYT1, -0.029)","(MAP2K1, -0.044)","(GNA15, -0.059)","(MAP3K1, -0.073)","(PPP3CB, -0.101)","(CAMK1, -0.109)","(RELA, -0.12)","(CALM3, -0.125)","(ELK1, -0.126)","(MAP2K6, -0.145)","(GNGT1, -0.15)"]
[658,"protein targeting (GO:0006605)",11,0.497,0.939,0.6004,"(GABARAPL2, 0.327)","(AP1M2, 0.285)","(GABARAP, 0.234)","(CDC37, 0.218)","(HPS4, 0.207)","(KIF13B, 0.113)","(HOMER3, 0.031)","(GABARAPL1, -0.019)","(LTBP2, -0.103)","(OIP106, -0.171)","(NLGN1, -0.259)"]
[658,"longevityPathway BioCarta",14,0.497,0.939,1,"(SOD1, 1.163)","(FOXO3A, 0.186)","(IGF1, 0.179)","(GHR, 0.147)","(GH1, 0.138)","(SOD2, -0.028)","(CAT, -0.029)","(PIK3R1, -0.059)","(HRAS, -0.067)","(PIK3CA, -0.069)","(IGF1R, -0.078)","(SOD3, -0.08)","(SHC1, -0.089)","(AKT1, -0.162)"]
[660,"positive regulation of transcription from RNA polymerase II promoter (GO:0045944)",4,0.498,0.939,0.92999,"(FOXD3, 0.302)","(NCOA6, 0.288)","(ATF4, 0.104)","(RUNX1, -0.113)"]
[661,"ranPathway BioCarta",5,0.501,0.942,0.60727,"(RANBP2, 0.569)","(CHC1, 0.447)","(RANBP1, 0.177)","(RANGAP1, -0.312)","(RAN, -0.312)"]
[661,"malatexPathway BioCarta",8,0.501,0.942,0.74967,"(ACLY, 1.347)","(SLC25A1, 0.161)","(MDH1, 0.137)","(SLC25A11, -0.002)","(PDHA1, -0.055)","(PC, -0.08)","(CS, -0.172)","(ME1, -0.261)"]
[661,"mitochondriaPathway BioCarta",21,0.501,0.942,0.84509,"(DFFB, 0.524)","(BIRC3, 0.457)","(CASP3, 0.36)","(BIRC2, 0.183)","(BAK1, 0.174)","(BIK, 0.17)","(BAX, 0.124)","(BIRC4, 0.082)","(DIABLO, 0.063)","(CASP6, 0.041)","(BCL2, 0.028)","(CYCS, 0.023)","(CASP7, 0.008)","(BCL2L1, -0.047)","(CASP9, -0.054)","(BID, -0.057)","(ENDOG, -0.065)","(CASP8, -0.079)","(DFFA, -0.096)","(APAF1, -0.108)","(PDCD8, -0.131)"]
[661,"metal ion homeostasis (GO:0006875)",2,0.501,0.942,0.96937,"(MTL5, 0.305)","(CLDN16, 0.134)"]
[665,"actin filament-based movement (GO:0030048)",5,0.502,0.942,0.83748,"(EVL, 0.967)","(APBB2, 0.209)","(APBB1, -0.021)","(MYO1E, -0.075)","(MYO9B, -0.291)"]
[666,"response to stress (GO:0006950)",43,0.503,0.942,0.71022,"(HYOU1, 0.486)","(MAPK13, 0.407)","(NPM1, 0.404)","(GSTA3, 0.38)","(PTK2B, 0.321)","(MAPK11, 0.305)","(MAP4K4, 0.184)","(GADD45G, 0.174)","(RPS6KA5, 0.163)","(MAPK14, 0.123)","(MAP4K3, 0.07)","(PRKRIR, 0.067)","(GADD45B, 0.053)","(C5, 0.053)","(MAP4K2, 0.036)","(SMAD7, 0.023)","(EPO, 0.009)","(SGK, 0.005)","(VEGF, 0)","(MAPK1, 0)","(CGREF1, 0)","(MAP3K4, 0)","(AHR, 0)","(CGRRF1, -0.004)","(MAP4K5, -0.005)","(AIF1, -0.007)","(GSTT1, -0.013)","(AHSA1, -0.018)","(MAP3K5, -0.021)","(TP53I11, -0.027)","(DUSP10, -0.032)","(MAPKAPK5, -0.049)","(SNN, -0.05)","(ATF4, -0.05)","(MAPK8, -0.061)","(ZNF443, -0.074)","(MAP2K7, -0.076)","(GSTA4, -0.085)","(TNIK, -0.085)","(MAP4K1, -0.092)","(MAPK9, -0.107)","(STIP1, -0.112)","(PINK1, -0.139)"]
[667,"receptor guanylyl cyclase signaling pathway (GO:0007168)",4,0.504,0.942,0.92171,"(GUCY2D, 0.494)","(GUCY2C, 0.179)","(GUCA1B, 0.038)","(GUCY2F, -0.122)"]
[667,"phototransduction, visible light (GO:0007603)",3,0.504,0.942,1,"(PDE6B, 0.605)","(RHO, 0.065)","(ABCA4, -0.159)"]
[669,"monocarboxylic acid transport (GO:0015718)",5,0.505,0.942,0.84903,"(SLC16A3, 1.135)","(SLC16A5, 0.105)","(SLC16A6, -0.109)","(SLC16A4, -0.145)","(SLC16A2, -0.184)"]
[669,"vitcbPathway BioCarta",10,0.505,0.942,0.87261,"(COL4A1, 0.774)","(P4HB, 0.394)","(COL4A6, 0.215)","(COL4A5, 0.041)","(COL4A3, 0.014)","(COL4A2, -0.073)","(SLC2A1, -0.075)","(COL4A4, -0.091)","(SLC23A2, -0.105)","(SLC2A3, -0.117)"]
[671,"learning (GO:0007612)",2,0.506,0.942,0.96261,"(FYN, 0.564)","(DLG4, -0.287)"]
[672,"MAP00500 Starch and sucrose metabolism GenMAPP",21,0.507,0.942,0.81682,"(GPI, 0.641)","(UGT2B4, 0.449)","(MGAM, 0.287)","(AGL, 0.247)","(UGP2, 0.151)","(GYS2, 0.119)","(PYGB, 0.1)","(PYGL, 0.096)","(HK3, 0.085)","(GUSB, 0.049)","(HK1, 0.04)","(GBE1, -0.016)","(G6PC, -0.018)","(GCK, -0.035)","(PYGM, -0.053)","(HK2, -0.073)","(ADH6, -0.078)","(UGT2B15, -0.13)","(PGM1, -0.154)","(GYS1, -0.159)","(GAA, -0.182)"]
[673,"shhPathway BioCarta",15,0.509,0.942,0.8937,"(GLI3, 0.921)","(PRKACB, 0.237)","(PRKAR2A, 0.174)","(PRKAR2B, 0.166)","(SMO, 0.13)","(PRKAR1B, 0.115)","(GSK3B, 0.1)","(SHH, 0.055)","(GLI, 0.032)","(DYRK1A, -0.028)","(PTCH, -0.069)","(GLI2, -0.077)","(DYRK1B, -0.114)","(PRKACG, -0.118)","(PRKAR1A, -0.131)"]
[673,"tricarboxylic acid cycle (GO:0006099)",5,0.509,0.942,0.93336,"(PDHB, 0.925)","(SDHB, 0.295)","(SDHA, 0.106)","(SDHD, -0.213)","(ME1, -0.335)"]
[673,"MAP00150 Androgen and estrogen metabolism GenMAPP",17,0.509,0.942,1,"(ARSE, 0.59)","(UGT2B4, 0.47)","(HSD17B3, 0.42)","(SRD5A1, 0.265)","(STS, 0.221)","(SRD5A2, 0.133)","(HSD11B2, 0.017)","(ARSD, -0.025)","(ADH6, -0.026)","(HSD17B2, -0.043)","(HSD11B1, -0.051)","(HSD3B2, -0.054)","(UGT2B15, -0.087)","(CYP11B2, -0.089)","(CYP11B1, -0.097)","(AKR1D1, -0.123)","(HSD3B1, -0.13)"]
[676,"regulation of chromatin assembly or disassembly (GO:0001672)",2,0.51,0.944,0.89033,"(TLK1, 0.409)","(TLK2, -0.026)"]
[677,"crebPathway CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling.",26,0.511,0.947,0.80485,"(GNAS, 0.51)","(CREB1, 0.378)","(MAPK14, 0.289)","(RAC1, 0.273)","(RPS6KA5, 0.256)","(PRKACB, 0.191)","(PRKAR2A, 0.156)","(MAPK3, 0.142)","(CAMK2A, 0.109)","(PRKAR2B, 0.109)","(ADCY1, 0.105)","(PRKAR1B, 0.101)","(PIK3R1, 0.035)","(SOS1, 0.032)","(RPS6KA1, 0)","(MAPK1, -0.008)","(GRB2, -0.01)","(CAMK2B, -0.036)","(HRAS, -0.038)","(CAMK2G, -0.041)","(PRKACG, -0.047)","(PRKCB1, -0.089)","(PRKCA, -0.1)","(PIK3CA, -0.136)","(PRKAR1A, -0.138)","(AKT1, -0.156)"]
[678,"nucleotide-excision repair (GO:0006289)",9,0.514,0.95,0.90901,"(ERCC1, 0.459)","(POLL, 0.368)","(DDB1, 0.34)","(RAD23A, 0.1)","(XPC, 0.047)","(TP53, 0.033)","(DDB2, 0.007)","(ERCC4, -0.114)","(RAD23B, -0.242)"]
[678,"regulation of JNK cascade (GO:0046328)",3,0.514,0.95,0.91924,"(MAPK8IP2, 0.577)","(MAPK8IP1, 0.308)","(MAPK8IP3, -0.282)"]
[680,"MAP00632 Benzoate degradation GenMAPP",7,0.515,0.951,1,"(HADHA, 0.513)","(ACYP1, 0.368)","(ECHS1, 0.18)","(GCDH, 0.141)","(ACYP2, 0.02)","(ACAT1, -0.037)","(EHHADH, -0.204)"]
[681,"positive regulation of interleukin-13 biosynthesis (GO:0045368)",2,0.516,0.952,0.99348,"(TLR4, 0.526)","(IRF4, -0.187)"]
[682,"blood coagulation (GO:0007596)",35,0.517,0.953,0.64286,"(PROS1, 0.648)","(F2RL3, 0.329)","(ADORA2A, 0.319)","(PLAT, 0.289)","(SERPINE1, 0.231)","(C4BPB, 0.202)","(F12, 0.184)","(F5, 0.178)","(GGCX, 0.167)","(ITGA2, 0.132)","(GP9, 0.122)","(WAS, 0.116)","(F2RL2, 0.094)","(F13B, 0.069)","(THBD, 0.061)","(LMAN1, 0.035)","(THBS1, 0.033)","(GNA12, 0.023)","(F7, 0.021)","(F9, 0.015)","(F2R, 0.014)","(ITGB3, 0)","(F8, -0.008)","(PLG, -0.013)","(F10, -0.024)","(CD59, -0.026)","(TBXAS1, -0.03)","(MMRN1, -0.047)","(GNAQ, -0.062)","(HNF4A, -0.076)","(F13A1, -0.098)","(CD36, -0.106)","(PABPC4, -0.112)","(TFPI, -0.122)","(ENTPD1, -0.134)"]
[683,"transcription (GO:0006350)",14,0.518,0.956,0.77174,"(DRG1, 0.495)","(CREB3, 0.418)","(PWP1, 0.173)","(PPP5C, 0.149)","(POLR2H, 0.146)","(GRLF1, 0.144)","(NFKBIB, 0.07)","(CREBL1, 0.069)","(FUBP3, 0.067)","(PTMA, -0.019)","(XAB2, -0.041)","(CEBPA, -0.104)","(NRIP1, -0.185)","(ZF, -0.218)"]
[684,"tercPathway BioCarta",6,0.52,0.957,0.81847,"(RB1, 0.625)","(NFYA, 0.219)","(SP3, 0.06)","(NFYB, -0.034)","(NFYC, -0.037)","(SP1, -0.264)"]
[684,"creatine biosynthesis (GO:0006601)",2,0.52,0.957,0.98457,"(GAMT, 0.319)","(GATM, -0.016)"]
[686,"cell adhesion molecule activity OBSOLETE. Mediates the adhesion of the cell to other cells or to the extracellular matrix.",109,0.521,0.96,0.98027,"(NINJ1, 0.566)","(LU, 0.462)","(SERF2, 0.355)","(CPNE3, 0.285)","(EVA1, 0.278)","(ARHE, 0.278)","(CIB1, 0.246)","(CD164, 0.218)","(PCDHB11, 0.213)","(CHL1, 0.209)","(CSPG4, 0.204)","(THBS4, 0.204)","(TM4SF8, 0.2)","(SELP, 0.194)","(CNTN2, 0.19)","(CD22, 0.172)","(CD151, 0.165)","(VWF, 0.155)","(SELE, 0.153)","(BYSL, 0.124)","(DSC3, 0.11)","(THBS2, 0.108)","(CDH3, 0.072)","(DSCAM, 0.066)","(CCL3, 0.059)","(DSG1, 0)","(MPZ, 0)","(CD36, 0)","(FGA, 0)","(CD33, 0)","(CPNE1, 0)","(GPA33, 0)","(CDH13, 0)","(BAIAP2, 0)","(DCTN6, 0)","(CTNNB1, 0)","(CD99, 0)","(FGB, 0)","(DSC1, 0)","(PPFIA2, 0)","(IL1B, 0)","(PLAU, 0)","(MAEA, 0)","(SPN, 0)","(DSC2, 0)","(MCAM, 0)","(PCDH12, 0)","(CORO1C, 0)","(NEO1, 0)","(MFGE8, 0)","(PCDHB12, 0)","(NRCAM, 0)","(PPFIA1, 0)","(VCAM1, 0)","(CDH2, 0)","(GP5, 0)","(PCDHB6, 0)","(OCLN, 0)","(NINJ2, 0)","(VTN, 0)","(TYRO3, 0)","(OPCML, 0)","(CEACAM1, 0)","(DGCR6, 0)","(ZYX, 0)","(ENTPD1, 0)","(PECAM1, 0)","(PCDHA3, 0)","(DSG3, 0)","(ICAM1, 0)","(ALCAM, 0)","(ICAM2, 0)","(L1CAM, 0)","(FLOT2, 0)","(ICAM3, 0)","(FN1, 0)","(CD226, 0)","(PCDH11X, 0)","(CDSN, 0)","(NCAM1, 0)","(LY9, 0)","(ICAM5, 0)","(CD6, 0)","(PCDH1, 0)","(FAT, 0)","(CD2, 0)","(CDH15, 0)","(PSORS1C1, 0)","(EMILIN1, 0)","(ICAM4, 0)","(PCDHB3, 0)","(IGSF1, 0)","(DPT, 0)","(PKP3, 0)","(NK4, 0)","(CD58, 0)","(PNN, 0)","(PKP1, 0)","(TM4SF6, 0)","(FGG, 0)","(SELL, 0)","(SPG7, 0)","(F11R, 0)","(FEZ2, 0)","(PAP, 0)","(CNTN1, 0)","(THBS1, 0)","(CDH1, 0)","(GP9, 0)"]
[687,"mitotic metaphase plate congression (GO:0007080)",2,0.522,0.963,0.88067,"(CDC23, 0.48)","(CENPE, -0.202)"]
[688,"transmembrane receptor protein tyrosine kinase activation (dimerization) (GO:0007171)",2,0.524,0.966,0.61127,"(ADRB2, 0.799)","(PRLR, -0.307)"]
[689,"cell surface receptor linked signal transduction (GO:0007166)",96,0.525,0.966,0.59072,"(BAG1, 0.436)","(PLCG2, 0.308)","(IL12RB1, 0.293)","(INHA, 0.289)","(IL6R, 0.284)","(BIRC3, 0.269)","(TTRAP, 0.212)","(BIRC2, 0.185)","(MAPK14, 0.182)","(TNFRSF14, 0.182)","(IL12RB2, 0.169)","(ANXA1, 0.167)","(DOK1, 0.155)","(FLNA, 0.135)","(SAG, 0.129)","(MIF, 0.12)","(KLRC1, 0.106)","(CD28, 0.105)","(CD14, 0.098)","(AGER, 0.086)","(RAMP2, 0.085)","(STC2, 0.083)","(GOLGA5, 0.054)","(MERTK, 0.054)","(TACSTD2, 0.045)","(PIP5K2B, 0.031)","(BRD8, 0.03)","(LIFR, 0.029)","(SIRPB1, 0.006)","(STC1, 0)","(PDGFA, 0)","(MPL, 0)","(CD79A, 0)","(LY6E, 0)","(GLRA1, 0)","(TNFRSF13B, 0)","(GLRB, 0)","(ECGF1, 0)","(CD59, 0)","(RAMP3, 0)","(MARCO, 0)","(IFNAR2, 0)","(CD3D, 0)","(IFNB1, 0)","(ASGR2, 0)","(CD2, 0)","(ISGF3G, 0)","(NPR2, 0)","(TNFRSF10B, 0)","(LEPR, 0)","(INHBA, 0)","(PRKCA, 0)","(IL6ST, 0)","(LILRB5, 0)","(CTF1, 0)","(MKNK2, 0)","(CXCL10, 0)","(IL6, 0)","(IL7R, 0)","(LILRB3, 0)","(INS, 0)","(GEM, 0)","(CD160, 0)","(HRMT1L2, 0)","(HRAS, 0)","(IL1R1, 0)","(LILRA1, 0)","(PDGFRA, 0)","(AGT, 0)","(IFNAR1, 0)","(KLRD1, 0)","(IFNGR2, 0)","(LILRB2, 0)","(IL13RA1, 0)","(KLRF1, 0)","(MYD88, 0)","(CSF2, 0)","(TNFRSF25, 0)","(BSG, 0)","(IFITM1, 0)","(IFNG, 0)","(KHDRBS1, 0)","(FADD, 0)","(DOK2, 0)","(LIF, 0)","(CD3G, 0)","(CD19, 0)","(CBL, 0)","(GLRA2, 0)","(CD69, 0)","(IFNA2, 0)","(IL2RA, 0)","(GP1BA, 0)","(PRL, 0)","(LY96, -0.007)","(PTPRC, -0.009)"]
[689,"inflammatory response (GO:0006954)",102,0.525,0.966,0.73002,"(IL1RAP, 0.696)","(NFKB1, 0.404)","(LTB4R, 0.369)","(IL9, 0.327)","(HDAC5, 0.325)","(NOS2A, 0.274)","(MGLL, 0.263)","(ANXA1, 0.218)","(ADORA2A, 0.213)","(CCL21, 0.209)","(GPR68, 0.204)","(CXCL14, 0.203)","(IL8RA, 0.202)","(BCL6, 0.172)","(NFE2L1, 0.17)","(HDAC9, 0.152)","(CCL20, 0.151)","(XCR1, 0.138)","(SELE, 0.138)","(CCL22, 0.123)","(MEFV, 0.111)","(NFATC3, 0.104)","(PROCR, 0.104)","(CCR1, 0.102)","(CCL4, 0.09)","(CEBPB, 0.09)","(CXCL12, 0.088)","(NFX1, 0.07)","(ABCF1, 0.066)","(FOS, 0.061)","(IL5, 0.06)","(AOC3, 0.045)","(HDAC4, 0.045)","(IL1RN, 0.036)","(ALOX15, 0.03)","(CXCL6, 0)","(FPRL1, 0)","(CCL11, 0)","(CRP, 0)","(CYBB, 0)","(IRF7, 0)","(CIAS1, 0)","(TACR1, 0)","(NFATC4, 0)","(ALOX5, 0)","(CD97, 0)","(AOX1, 0)","(CXCL11, 0)","(ORM1, 0)","(C3AR1, 0)","(TNFAIP6, 0)","(CCL3, 0)","(AIF1, 0)","(C5, 0)","(VPS45A, 0)","(KNG1, 0)","(RIPK2, 0)","(NR3C1, 0)","(CCL23, 0)","(CXCL10, 0)","(ALOX5AP, 0)","(SCYE1, 0)","(PRG2, 0)","(PLA2G7, 0)","(CCL24, 0)","(CXCL9, 0)","(PLA2G2D, 0)","(AOAH, 0)","(PTAFR, 0)","(F11R, 0)","(AGER, 0)","(CXCL5, 0)","(IL1R1, 0)","(CCL13, 0)","(CXCL2, 0)","(CCR3, 0)","(FPR1, 0)","(HDAC7A, 0)","(S100A12, 0)","(CCR2, 0)","(HRH1, 0)","(ADORA1, 0)","(S100A8, 0)","(TNF, 0)","(S100A9, 0)","(BDKRB2, 0)","(CCR7, 0)","(PLA2G2E, 0)","(TPST1, 0)","(IL8RB, 0)","(CCL5, 0)","(NMI, 0)","(IL13, 0)","(PTX3, 0)","(CCR4, 0)","(CCL1, 0)","(APOL3, 0)","(IFNA2, 0)","(BDKRB1, 0)","(IL10RB, 0)","(LY75, -0.042)","(ADORA3, -0.075)"]
[689,"induction of positive chemotaxis (GO:0050930)",2,0.525,0.966,0.99052,"(SPP1, 0.387)","(IL8, 0.077)"]
[689,"ST Fas Signaling Pathway Signalling Transduction KE",64,0.525,0.966,1,"(NFKBIA, 0.667)","(NFKB1, 0.512)","(MET, 0.346)","(IL1A, 0.282)","(PFN2, 0.248)","(FAF1, 0.227)","(CASP3, 0.226)","(BTK, 0.183)","(TRAF2, 0.167)","(NFKBIL1, 0.131)","(MAPK8IP1, 0.096)","(DIABLO, 0.064)","(CAD, 0.058)","(NFKBIB, 0.04)","(NFKB2, 0.037)","(CASP8, 0.034)","(MAPK8IP2, 0.022)","(HRB, 0.021)","(BIRC4, 0.02)","(FAIM2, 0.013)","(RIPK1, 0.007)","(TUFM, 0)","(VIL2, 0)","(ADPRT, 0)","(NR0B2, 0)","(PFN1, 0)","(MAP2K7, 0)","(EPHB2, 0)","(HSPB1, 0)","(MAP3K1, 0)","(NFKBIL2, 0)","(BAK1, 0)","(ROCK1, 0)","(MAP3K5, 0)","(MAPK10, 0)","(TNFRSF6, 0)","(DAXX, 0)","(MAPK8, 0)","(EGFR, 0)","(BFAR, 0)","(TPX2, 0)","(MCP, 0)","(NFAT5, 0)","(CASP10, 0)","(CDK2AP1, 0)","(MAP2K4, 0)","(IL8, 0)","(DEDD, 0)","(CSNK1A1, 0)","(CASP8AP2, 0)","(RALBP1, 0)","(DFFA, 0)","(FADD, -0.007)","(MAPK1, -0.008)","(BAX, -0.008)","(SMPD1, -0.013)","(TP53, -0.013)","(TNFRSF6B, -0.013)","(PTPN13, -0.017)","(FREQ, -0.021)","(CD7, -0.021)","(NFKBIE, -0.032)","(MAPK9, -0.043)","(MAPK8IP3, -0.196)"]
[689,"ST Phosphoinositide 3 Kinase Pathway Signalling Transduction KE",34,0.525,0.966,1,"(AKT2, 0.588)","(RPS6KB1, 0.57)","(SFN, 0.424)","(FOXO1A, 0.402)","(BTK, 0.288)","(INPP5D, 0.176)","(IARS, 0.169)","(RPS6KA2, 0.163)","(DAF, 0.116)","(SOS2, 0.104)","(GSK3B, 0.078)","(BAD, 0.061)","(GSK3A, 0.037)","(RPS6KA1, 0.025)","(SHC1, 0.014)","(YWHAZ, 0)","(SOS1, 0)","(IGFBP1, 0)","(YWHAH, -0.002)","(RPS6KA3, -0.003)","(DAPP1, -0.005)","(GRB2, -0.005)","(AKT1, -0.008)","(PPP1R13B, -0.01)","(YWHAE, -0.015)","(TEC, -0.04)","(PDK1, -0.077)","(PTEN, -0.077)","(AKT3, -0.08)","(YWHAB, -0.096)","(YWHAQ, -0.101)","(PSCD3, -0.121)","(CDKN2A, -0.136)","(PIK3CA, -0.165)"]
[694,"hivnefPathway BioCarta",58,0.526,0.966,0.86334,"(NFKBIA, 0.689)","(NFKB1, 0.578)","(TRADD, 0.486)","(DFFB, 0.31)","(BIRC3, 0.219)","(NUMA1, 0.206)","(CASP3, 0.197)","(RB1, 0.193)","(TNFRSF1A, 0.148)","(TRAF2, 0.12)","(BIRC2, 0.109)","(TNFSF6, 0.093)","(TNFRSF6, 0.052)","(TRAF1, 0.035)","(RIPK1, 0.025)","(CASP8, 0.015)","(BIRC4, 0.001)","(PSEN1, 0)","(PSEN2, 0)","(CASP6, 0)","(CASP7, 0)","(CFLAR, 0)","(MAP2K7, 0)","(PRKDC, 0)","(MAP3K1, 0)","(BCL2, 0)","(PTK2, 0)","(SPTAN1, 0)","(LMNB1, 0)","(CYCS, 0)","(MDM2, 0)","(DAXX, 0)","(MAPK8, 0)","(TNFRSF1B, 0)","(LMNA, 0)","(ACTG1, 0)","(FADD, 0)","(CDC2L1, 0)","(PAK2, 0)","(TNF, -0.003)","(PRKCD, -0.007)","(LMNB2, -0.011)","(ADPRT, -0.016)","(ARHGDIB, -0.017)","(BAG4, -0.021)","(CHUK, -0.03)","(APAF1, -0.035)","(CASP9, -0.041)","(CRADD, -0.073)","(MAP3K5, -0.074)","(CDC2L2, -0.077)","(MAP3K14, -0.109)","(DFFA, -0.111)","(CASP2, -0.113)","(RELA, -0.119)","(BID, -0.127)","(GSN, -0.146)","(RASA1, -0.204)"]
[694,"neurotransmitter secretion (GO:0007269)",6,0.526,0.966,0.97594,"(KCNMA1, 0.797)","(RAB3A, 0.546)","(BAIAP3, -0.105)","(SYN3, -0.203)","(SYT1, -0.22)","(HRH3, -0.257)"]
[696,"anti-apoptosis (GO:0006916)",60,0.527,0.966,0.79014,"(NFKB1, 0.515)","(BAG1, 0.488)","(FOXO1A, 0.347)","(IL1A, 0.29)","(BIRC3, 0.259)","(SERPINB2, 0.235)","(TIAF1, 0.195)","(CBX4, 0.158)","(IER3, 0.147)","(RNF7, 0.139)","(SON, 0.129)","(NTF3, 0.121)","(SPP1, 0.117)","(NME5, 0.105)","(PSEN1, 0.102)","(BRAF, 0.1)","(GDNF, 0.067)","(SNCA, 0.065)","(API5, 0.054)","(HDAC1, 0.048)","(ALOX12, 0.042)","(PRKCZ, 0.034)","(NOL3, 0.024)","(TNFSF18, 0.021)","(BECN1, 0.021)","(BNIP2, 0.008)","(RELA, 0)","(CFLAR, 0)","(BCL2, 0)","(NOTCH2, 0)","(BCL2L1, 0)","(SPHK1, 0)","(BIRC1, 0)","(BIRC5, 0)","(BNIP3, 0)","(PEA15, 0)","(IGF1R, 0)","(BCL2A1, 0)","(BCL2L2, 0)","(SEMA4D, 0)","(MTL5, 0)","(HDAC3, 0)","(MYBL2, 0)","(SOCS2, 0)","(TGFB1, 0)","(NRG2, 0)","(BAG4, 0)","(TNFRSF6B, 0)","(PAX7, 0)","(BCL2L10, 0)","(AKT1, 0)","(TXNDC, -0.006)","(CCL2, -0.007)","(SOCS3, -0.008)","(MPO, -0.015)","(BNIP1, -0.016)","(MCL1, -0.017)","(BIRC4, -0.041)","(TNFRSF10D, -0.079)","(TNF, -0.115)"]
[696,"protein import into nucleus (GO:0006606)",4,0.527,0.966,0.8675,"(PTTG1IP, 0.563)","(RANBP2, 0.482)","(MCM3AP, -0.223)","(TPR, -0.27)"]
[696,"hsp27Pathway BioCarta",14,0.527,0.966,1,"(IL1A, 0.624)","(CASP3, 0.416)","(ACTA1, 0.229)","(MAPKAPK3, 0.182)","(TNFRSF6, 0.175)","(CYCS, 0.094)","(BCL2, 0.049)","(HSPB1, 0.04)","(CASP9, -0.043)","(DAXX, -0.051)","(TNF, -0.061)","(MAPKAPK2, -0.088)","(APAF1, -0.11)","(HSPB2, -0.112)"]
[699,"SA B CELL RECEPTOR COMPLEXES SigmaAldrich",24,0.528,0.966,0.51597,"(VAV1, 0.858)","(ATF2, 0.39)","(JUN, 0.377)","(RAC1, 0.218)","(FOS, 0.153)","(PAPPA, 0.126)","(SOS1, 0.047)","(MAPK3, 0.029)","(GRB2, 0.025)","(LYN, 0.013)","(VAV2, 0.005)","(MAPK1, -0.004)","(MAP3K1, -0.014)","(HRAS, -0.035)","(BCR, -0.047)","(RPS6KA1, -0.053)","(SHC1, -0.055)","(VAV3, -0.075)","(MAP2K1, -0.087)","(BLNK, -0.101)","(MAPK8IP3, -0.111)","(ELK1, -0.118)","(SYK, -0.124)","(RPS6KA3, -0.143)"]
[700,"regulation of G-protein coupled receptor protein signaling pathway (GO:0008277)",20,0.529,0.966,0.71133,"(GIT2, 0.48)","(GRK1, 0.444)","(GRK5, 0.393)","(RGS16, 0.385)","(GIT1, 0.189)","(RGS3, 0.113)","(RGS9, 0.084)","(RGS4, 0.052)","(RGS5, 0.039)","(RGS20, 0.034)","(RGS2, -0.015)","(GNG4, -0.018)","(RGS11, -0.03)","(GRK6, -0.053)","(ECE2, -0.073)","(RGS12, -0.074)","(RGS14, -0.074)","(RAMP1, -0.105)","(GNG7, -0.123)","(GRK4, -0.187)"]
[701,"response to organic substance (GO:0010033)",4,0.53,0.968,0.80727,"(PPP2R1B, 0.438)","(DGKD, 0.201)","(ABCG1, -0.094)","(AQP9, -0.125)"]
[701,"cation transport (GO:0006812)",6,0.53,0.968,0.84188,"(PKD2L1, 0.611)","(PKD2, 0.346)","(HCN4, 0.045)","(CHRNB1, -0.091)","(TRPC6, -0.127)","(HCN2, -0.131)"]
[703,"MAP00100 Sterol biosynthesis GenMAPP",10,0.531,0.969,0.40437,"(NQO2, 0.804)","(FDFT1, 0.741)","(HMGCR, 0.189)","(IDI1, 0.046)","(SQLE, -0.075)","(FDPS, -0.082)","(LSS, -0.1)","(MVK, -0.114)","(SC5DL, -0.164)","(MVD, -0.265)"]
[704,"thelperPathway BioCarta",13,0.533,0.972,1,"(CD4, 0.326)","(CD3E, 0.32)","(CD28, 0.287)","(ITGB2, 0.266)","(TRA@, 0.249)","(ITGAL, 0.156)","(CD2, -0.01)","(CD3G, -0.025)","(THY1, -0.042)","(CD3D, -0.069)","(ICAM1, -0.079)","(PTPRC, -0.083)","(CD3Z, -0.174)"]
[705,"tnf and fas network BioCarta",22,0.534,0.973,0.90317,"(TRAF5, 0.592)","(TNFAIP3, 0.344)","(BIRC2, 0.278)","(TNFRSF1A, 0.256)","(TRAF2, 0.235)","(TRAF3, 0.155)","(GAPD, 0.113)","(TRAF1, 0.112)","(BIRC4, 0.11)","(TNFSF6, 0.088)","(TRIP, 0.076)","(BIRC1, 0.068)","(TNFRSF6, 0.031)","(TRAF6, 0.007)","(SMN1, -0.004)","(BIRC5, -0.006)","(DAXX, -0.012)","(ACTB, -0.034)","(TNF, -0.074)","(TNFRSF1B, -0.078)","(TNFSF10, -0.112)","(TANK, -0.112)"]
[706,"HOX LIST JP Manually Curated",56,0.536,0.975,0.48485,"(SCMH1, 0.475)","(RING1, 0.4)","(PHC1, 0.399)","(PHC2, 0.338)","(SCML1, 0.285)","(HOXA4, 0.272)","(HOXB1, 0.238)","(HOXD4, 0.227)","(PBX1, 0.215)","(CBX4, 0.207)","(HOXC13, 0.206)","(HOXB13, 0.202)","(DLX4, 0.18)","(HOXA10, 0.149)","(SCML2, 0.142)","(HLX1, 0.139)","(CBX8, 0.083)","(RNF110, 0.008)","(HOXA1, 0.006)","(PRRX1, 0.006)","(HOXA6, 0)","(HOXD10, 0)","(HHEX, 0)","(HOXB5, 0)","(HOXD11, 0)","(HOXA5, 0)","(HOXD13, 0)","(GBX2, 0)","(HOXC10, 0)","(HOXA11, 0)","(HOXD1, 0)","(HOXD12, 0)","(HOXB3, 0)","(HOXB2, 0)","(HOXB7, 0)","(HOXC4, 0)","(JJAZ1, 0)","(EED, 0)","(ASXL1, 0)","(HOXA9, 0)","(HOXB6, 0)","(HOXD3, -0.007)","(HOXA7, -0.007)","(HOXD9, -0.008)","(HOXC8, -0.01)","(EZH1, -0.011)","(MEIS1, -0.019)","(HOXC11, -0.036)","(HOXA2, -0.039)","(EZH2, -0.039)","(HOXB9, -0.056)","(HOOK1, -0.074)","(LHX2, -0.098)","(BMI1, -0.127)","(YY1, -0.158)","(HOXA3, -0.192)"]
[706,"posterior compartment specification (GO:0007388)",2,0.536,0.975,0.95644,"(PBX3, 0.638)","(PBX2, -0.372)"]
[706,"estrogen receptor signaling pathway (GO:0030520)",4,0.536,0.975,0.99377,"(RBM9, 1.275)","(DDX54, -0.154)","(ESR2, -0.3)","(ARID1A, -0.428)"]
[709,"DNA ligation (GO:0006266)",2,0.538,0.978,1,"(XRCC6, 0.001)","(MGMT, 0)"]
[710,"G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) (GO:0007200)",17,0.54,0.978,0.65682,"(LTB4R, 0.787)","(F2RL3, 0.439)","(P2RY11, 0.398)","(P2RY4, 0.313)","(AGTR1, 0.209)","(HTR2B, 0.134)","(MC3R, -0.025)","(HRH1, -0.03)","(TACR1, -0.039)","(P2RY2, -0.064)","(IL8RB, -0.069)","(OXTR, -0.095)","(EDNRB, -0.108)","(CCKAR, -0.114)","(P2RY1, -0.135)","(NMBR, -0.159)","(P2RY6, -0.229)"]
[711,"il17Pathway BioCarta",16,0.541,0.978,0.89557,"(CSF3, 0.642)","(CD4, 0.368)","(CD3E, 0.301)","(IL17, 0.234)","(CD34, 0.23)","(TRA@, 0.198)","(IL6, 0.154)","(CD2, 0.011)","(CD8A, -0.043)","(CD58, -0.067)","(KITLG, -0.08)","(IL8, -0.09)","(IL3, -0.093)","(CD3D, -0.1)","(CD3G, -0.113)","(CD3Z, -0.124)"]
[711,"anterior compartment specification (GO:0007387)",2,0.541,0.978,0.95644,"(PBX3, 0.648)","(PBX2, -0.433)"]
[713,"polysaccharide metabolism (GO:0005976)",2,0.542,0.98,0.80334,"(CHST7, 0.667)","(CHST1, -0.305)"]
[714,"mprPathway BioCarta",23,0.543,0.981,0.8014,"(CAP1, 0.691)","(GNAS, 0.548)","(PRKACB, 0.225)","(ADCY1, 0.204)","(PRKAR2A, 0.177)","(PRKAR2B, 0.161)","(ACTA1, 0.151)","(MAPK3, 0.076)","(PRKAR1B, 0.069)","(GNB1, 0.047)","(CDC2, 0.005)","(RPS6KA1, 0.004)","(HRAS, -0.014)","(MAPK1, -0.023)","(SRC, -0.034)","(PIN1, -0.055)","(GNAI1, -0.061)","(MYT1, -0.066)","(PRKACG, -0.077)","(CCNB1, -0.081)","(CDC25C, -0.108)","(PRKAR1A, -0.135)","(GNGT1, -0.179)"]
[714,"actin filament bundle formation (GO:0051017)",5,0.543,0.981,0.93939,"(FSCN2, 0.729)","(FSCN1, 0.103)","(ACTN4, -0.112)","(VIL1, -0.122)","(EPB49, -0.144)"]
[716,"bile acid metabolism (GO:0008206)",3,0.544,0.984,1,"(ACOX2, 0.561)","(ACOX3, 0.275)","(NR1H4, -0.361)"]
[716,"EGF receptor signaling pathway BioCarta",12,0.544,0.984,1,"(EPS15, 0.461)","(EGF, 0.363)","(GRB7, 0.275)","(GAB1, 0.21)","(REPS2, 0.127)","(EGFR, 0.077)","(GRB2, 0.074)","(EREG, -0.025)","(NCK2, -0.03)","(EPS8, -0.058)","(SHC1, -0.078)","(SHC3, -0.189)"]
[716,"intermediate filament cytoskeleton organization and biogenesis (GO:0045104)",2,0.544,0.984,1,"(ERBB2IP, 0.002)","(DST, -0.001)"]
[719,"prostaglandin biosynthesis (GO:0001516)",4,0.545,0.987,1,"(MIF, 0.46)","(CD74, 0.451)","(PTGS1, -0.201)","(PTGDS, -0.205)"]
[720,"cell cycle regulator OBSOLETE (was not defined before being made obsolete).",25,0.546,0.987,0.55829,"(MPHOSPH6, 0.738)","(RGC32, 0.542)","(SRPK1, 0.411)","(CDKN1B, 0.209)","(MPHOSPH1, 0.194)","(CDC37, 0.175)","(CHES1, 0.175)","(BTG1, 0.054)","(CDK6, 0.052)","(MCM5, 0.013)","(BCL2, 0.013)","(ZRF1, -0.018)","(WEE1, -0.022)","(SPIN, -0.045)","(CDK7, -0.053)","(MPHOSPH10, -0.088)","(MPHOSPH9, -0.09)","(CDK5, -0.111)","(CDKN1A, -0.124)","(PRKR, -0.136)","(CDK5R1, -0.148)","(CDC45L, -0.152)","(YWHAQ, -0.154)","(CDC6, -0.179)","(BTG2, -0.186)"]
[720,"regulation of endocytosis (GO:0030100)",2,0.546,0.987,0.67062,"(AP2S1, 0.157)","(ZFYVE16, 0.085)"]
[720,"chrebpPathway Carbohydrate responsive element binding protein (chREBP) is a transcription factor inhibited by cAMP and activated by high carbohydrate levels.",20,0.546,0.987,0.8814,"(GNAS, 0.53)","(PPP2CA, 0.263)","(PRKACB, 0.197)","(PRKAR2B, 0.171)","(ADCY1, 0.127)","(PRKAR2A, 0.119)","(BUCS1, 0.087)","(BG1, 0.084)","(PRKAG2, 0.061)","(PRKAR1B, 0.06)","(PRKAB1, 0.059)","(WBSCR14, 0.017)","(GNB1, -0.016)","(PRKAB2, -0.046)","(PRKAG1, -0.079)","(PRKAR1A, -0.095)","(PRKAA1, -0.095)","(PRKAA2, -0.107)","(PRKACG, -0.119)","(GNGT1, -0.245)"]
[720,"translational elongation (GO:0006414)",2,0.546,0.987,0.91486,"(TSFM, 0.183)","(TUFM, 0.052)"]
[724,"internal protein amino acid acetylation (GO:0006475)",2,0.548,0.987,1,"(ARD1A, 0)","(HAT1, 0)"]
[725,"ghPathway BioCarta",27,0.549,0.989,0.49306,"(SLC2A4, 0.661)","(PLCG1, 0.5)","(TCF1, 0.321)","(SOCS1, 0.202)","(GH1, 0.185)","(SRF, 0.157)","(GHR, 0.093)","(RPS6KA1, 0.09)","(MAPK3, 0.056)","(RAF1, 0.048)","(SOS1, 0.032)","(IRS1, 0.027)","(GRB2, 0.005)","(MAPK1, 0)","(PIK3R1, -0.003)","(STAT5B, -0.009)","(STAT5A, -0.039)","(PTPN6, -0.039)","(SHC1, -0.058)","(HRAS, -0.06)","(PRKCB1, -0.063)","(INS, -0.072)","(INSR, -0.075)","(JAK2, -0.12)","(MAP2K1, -0.135)","(PIK3CA, -0.148)","(PRKCA, -0.156)"]
[725,"response to temperature stimulus (GO:0009266)",2,0.549,0.989,1,"(ACOT11, 0.003)","(FGF16, -0.001)"]
[727,"iron ion transport (GO:0006826)",3,0.55,0.989,0.99131,"(TFRC, 0.557)","(SLC11A2, 0.069)","(HFE, -0.246)"]
[727,"gabaPathway BioCarta",11,0.55,0.989,1,"(GABARAP, 0.375)","(GABRA1, 0.318)","(GABRA3, 0.222)","(NSF, 0.125)","(GPHN, 0.102)","(GABRA4, 0.061)","(SRC, 0.049)","(GABRA6, -0.016)","(GABRA2, -0.037)","(GABRA5, -0.109)","(DNM1, -0.242)"]
[729,"SIG PIP3SIGINCARDIACMYOCTES SignallingAlliance",65,0.552,0.991,1,"(RPS6KB1, 0.441)","(SLC2A4, 0.436)","(AKT2, 0.408)","(MET, 0.347)","(SFN, 0.332)","(CREB3, 0.295)","(TSC1, 0.27)","(CREB1, 0.235)","(CDKN1B, 0.167)","(IGF1, 0.151)","(GSK3B, 0.126)","(PARD6A, 0.123)","(RPS6KA2, 0.123)","(FOXO3A, 0.109)","(GSK3A, 0.072)","(F2RL2, 0.069)","(INPPL1, 0.058)","(YWHAH, 0.019)","(IRS1, 0.014)","(PARD3, 0.011)","(SOS2, 0.009)","(YWHAZ, 0)","(PSCD3, 0)","(PAK3, 0)","(MYC, 0)","(ERBB4, 0)","(PDK1, 0)","(CDC42, 0)","(IGFBP1, 0)","(GRB2, 0)","(CDK2, 0)","(NOLC1, 0)","(CDKN2A, 0)","(RPS6KA1, 0)","(BCL2L1, 0)","(SOS1, 0)","(GAB1, 0)","(YWHAE, 0)","(AKT1, 0)","(FRAP1, 0)","(GADD45A, 0)","(PTPN1, 0)","(AKT3, 0)","(PAK1, 0)","(SHC1, 0)","(EBP, 0)","(PAK7, 0)","(YWHAB, 0)","(IRS2, 0)","(BAD, 0)","(P101-PI3K, 0)","(PAK2, 0)","(PTEN, 0)","(PPP1R13B, -0.008)","(PTK2, -0.009)","(PIK3CA, -0.013)","(PAK6, -0.023)","(PAK4, -0.033)","(IFI27, -0.038)","(CREB5, -0.046)","(TSC2, -0.048)","(PIK3CD, -0.072)","(YWHAQ, -0.078)","(RPS6KA3, -0.107)","(IRS4, -0.137)"]
[730,"viral genome replication (GO:0019079)",8,0.553,0.992,0.95824,"(CCL4, 0.476)","(CTBP2, 0.466)","(HBXIP, 0.462)","(OPRK1, 0.123)","(DEK, 0.046)","(CTBP1, -0.093)","(CXCR6, -0.171)","(CCL2, -0.214)"]
[731,"regulation of protein catabolism (GO:0042176)",2,0.554,0.992,0.91416,"(FAF1, 0.557)","(MDM2, -0.304)"]
[731,"phosphatidylinositol biosynthesis (GO:0006661)",4,0.554,0.992,1,"(CD81, 0.382)","(IMPA1, 0.119)","(PIK4CB, 0.078)","(PIK4CA, -0.189)"]
[733,"mitotic checkpoint (GO:0007093)",5,0.555,0.992,0.72022,"(MAD2L1, 0.522)","(ZW10, 0.313)","(BUB1B, 0.137)","(KNTC1, -0.109)","(CHFR, -0.162)"]
[733,"germ cell development (GO:0007281)",3,0.555,0.992,0.79581,"(BAX, 0.383)","(DAZL, -0.002)","(DEAF1, -0.059)"]
[733,"SIG CHEMOTAXIS SignallingAlliance",43,0.555,0.992,0.95483,"(ARHGAP4, 0.549)","(CFL1, 0.499)","(AKT2, 0.496)","(MYLK, 0.293)","(BTK, 0.265)","(SAG, 0.224)","(GDI2, 0.195)","(RPS4X, 0.159)","(INPPL1, 0.151)","(ROCK2, 0.144)","(ANGPTL2, 0.125)","(WASF1, 0.099)","(ACTR3, 0.087)","(ITPR1, 0.053)","(PDK1, 0.013)","(RACGAP1, 0.009)","(ROCK1, 0.008)","(PAK2, 0.006)","(GDI1, 0)","(PAK3, 0)","(AKT3, 0)","(PAK7, 0)","(P101-PI3K, 0)","(ITPR3, 0)","(WASL, -0.011)","(PAK6, -0.012)","(PIK3R1, -0.014)","(PPP1R13B, -0.021)","(ARHGAP1, -0.029)","(ARHGEF11, -0.037)","(LIMK1, -0.046)","(RHO, -0.047)","(ITPR2, -0.051)","(PITX2, -0.055)","(ACTR2, -0.056)","(PIK3CG, -0.058)","(CDC42, -0.067)","(AKT1, -0.067)","(PIK3CA, -0.102)","(PAK1, -0.13)","(PIK3CD, -0.134)","(PTEN, -0.185)","(PAK4, -0.213)"]
[736,"inflamPathway BioCarta",29,0.556,0.992,0.51365,"(CSF3, 0.494)","(IL1A, 0.459)","(HLA-DRB1, 0.297)","(CD4, 0.261)","(CSF1, 0.236)","(IL12A, 0.229)","(IL6, 0.184)","(IL12B, 0.144)","(PDGFA, 0.099)","(CSF2, 0.098)","(IL5, 0.042)","(IL10, 0.035)","(IL3, 0.017)","(TGFB3, 0.006)","(IFNB1, 0.003)","(IL7, 0)","(IL13, -0.002)","(TNF, -0.019)","(HLA-DRA, -0.038)","(TGFB2, -0.038)","(IL8, -0.053)","(IFNA1, -0.061)","(LTA, -0.062)","(IL4, -0.09)","(IL2, -0.101)","(IFNG, -0.113)","(IL15, -0.116)","(TGFB1, -0.172)","(IL11, -0.204)"]
[736,"muscle contraction (GO:0006936)",66,0.556,0.992,0.60337,"(FXYD1, 0.858)","(LTB4R, 0.451)","(CKMT2, 0.319)","(SLC6A8, 0.312)","(KCNMA1, 0.247)","(CACNA1H, 0.231)","(SCN4A, 0.214)","(SLC8A1, 0.203)","(ROCK2, 0.136)","(KCNQ1, 0.134)","(UTS2, 0.111)","(GJA5, 0.094)","(TRDN, 0.094)","(CLCN1, 0.088)","(KCNH2, 0.083)","(KCNA1, 0.077)","(PABPN1, 0.075)","(CHRNE, 0.065)","(ASPH, 0.048)","(MYL3, 0.036)","(HRC, 0.025)","(GENX-3414, 0.009)","(DAG1, 0.008)","(HCN4, 0.007)","(GJA7, 0.005)","(SNTB1, 0)","(TBXA2R, 0)","(P2RXL1, 0)","(SSPN, 0)","(RYR1, 0)","(DES, 0)","(GNAO1, 0)","(KCNE2, 0)","(GALR2, 0)","(UTRN, 0)","(KCNJ12, 0)","(CHRNA1, 0)","(KCNE1, 0)","(CACNB1, 0)","(DMD, 0)","(VIPR1, 0)","(CRYAB, 0)","(OXTR, 0)","(SGCA, 0)","(FLII, 0)","(TACR2, 0)","(TAZ, 0)","(VIP, 0)","(GJA1, 0)","(CACNG1, 0)","(CHRNB1, 0)","(EMD, 0)","(GAMT, 0)","(NOS1, -0.007)","(SNTA1, -0.008)","(HCN2, -0.016)","(PLN, -0.017)","(CHRNG, -0.018)","(CACNA1S, -0.034)","(CHRND, -0.037)","(DMPK, -0.045)","(SCN7A, -0.047)","(SCN5A, -0.054)","(DYSF, -0.064)","(RYR2, -0.085)","(FER1L3, -0.089)"]
[736,"potassium ion transport (GO:0006813)",51,0.556,0.992,0.63158,"(KCNJ1, 0.513)","(KCNC4, 0.362)","(KCNA3, 0.265)","(KCNQ1, 0.204)","(KCNK1, 0.177)","(KCNA1, 0.174)","(KCNF1, 0.165)","(KCNJ4, 0.161)","(KCNG2, 0.158)","(KCNH1, 0.139)","(KCNC1, 0.137)","(KCND3, 0.134)","(KCNC3, 0.126)","(KCNH4, 0.1)","(KCNAB1, 0.085)","(KCNMB2, 0.076)","(KCNH2, 0.058)","(KCNN1, 0.054)","(KCNA2, 0.031)","(KCNQ4, 0.015)","(KCNJ15, 0.014)","(KCNS1, 0.007)","(KCNK4, 0)","(KCNQ3, 0)","(KCNE2, 0)","(KCNQ2, 0)","(KCNJ8, 0)","(ATP1A3, 0)","(CHP, 0)","(KCNMB1, 0)","(KCNA4, 0)","(KCNJ6, 0)","(KCNJ10, 0)","(KCNMB4, 0)","(KCNK5, 0)","(KCNJ5, -0.007)","(KCNMB3, -0.021)","(KCNN4, -0.048)","(KCNJ3, -0.055)","(KCNK3, -0.077)","(ATP1A1, -0.081)","(ABCC9, -0.089)","(KCNK7, -0.094)","(KCNB2, -0.103)","(KCNA5, -0.106)","(KCNE1, -0.107)","(ABCC8, -0.108)","(KCNJ12, -0.119)","(KCNS3, -0.119)","(ATP1A2, -0.145)","(KCNAB3, -0.183)"]
[736,"fcer1Pathway In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachnidonic acid release.",37,0.556,0.992,0.96687,"(VAV1, 0.661)","(PLA2G4A, 0.53)","(PLCG1, 0.399)","(JUN, 0.362)","(NFATC1, 0.28)","(BTK, 0.236)","(NFATC3, 0.224)","(MAPK3, 0.201)","(FCER1G, 0.199)","(FOS, 0.129)","(PPP3CC, 0.113)","(PAK2, 0.059)","(RAF1, 0.056)","(GRB2, 0.051)","(SOS1, 0.04)","(MAPK1, 0.023)","(LYN, 0.017)","(SYT1, 0)","(ELK1, 0)","(MAP3K1, -0.004)","(MAP2K1, -0.005)","(PIK3R1, -0.008)","(CALM2, -0.015)","(PPP3CB, -0.021)","(CALM1, -0.037)","(HRAS, -0.042)","(PRKCB1, -0.048)","(PIK3CA, -0.054)","(CALM3, -0.063)","(NFATC4, -0.074)","(SHC1, -0.075)","(PPP3CA, -0.077)","(FCER1A, -0.079)","(MAPK8, -0.089)","(SYK, -0.095)","(MAP2K4, -0.113)","(MAP2K7, -0.116)"]
[736,"CR ANGIOG PNAS 2001",10,0.556,0.992,1,"(VEGFB, 0.561)","(FLT4, 0.263)","(ANGPTL2, 0.255)","(BAI1, 0.047)","(ENG, 0.035)","(THBS1, 0.027)","(VEGF, -0.047)","(FLT1, -0.098)","(KDR, -0.122)","(PECAM1, -0.247)"]
[741,"protein amino acid dephosphorylation (GO:0006470)",54,0.559,0.996,1,"(PTPRM, 0.807)","(DUSP3, 0.352)","(SBF1, 0.341)","(PTPN3, 0.279)","(PTPN4, 0.269)","(EPM2A, 0.246)","(PPP2CA, 0.172)","(PTPRT, 0.15)","(PPP2R1B, 0.138)","(PPP6C, 0.133)","(PTPRN2, 0.13)","(PPP5C, 0.094)","(PPM1D, 0.089)","(PTPN13, 0.07)","(PPP2R2A, 0.049)","(PPP2R1A, 0.04)","(MTMR7, 0.035)","(PTPRD, 0.029)","(PTPN7, 0.025)","(PPM1B, 0.017)","(MTMR3, 0.016)","(DUSP13, 0.011)","(MTMR1, 0.009)","(PTPN14, 0)","(PTPN12, 0)","(PTPRE, 0)","(PTPN18, 0)","(PTPRO, 0)","(PTPN21, 0)","(PPEF2, 0)","(PTPN2, 0)","(PTPN22, 0)","(PTPRB, 0)","(PTPN6, 0)","(DUSP4, 0)","(DUSP9, 0)","(PTPRS, 0)","(DUSP5, 0)","(DUSP8, 0)","(DUSP2, 0)","(PPEF1, -0.007)","(CTDP1, -0.007)","(PTPRR, -0.01)","(PPP3CB, -0.011)","(PPP2R3A, -0.019)","(DUSP10, -0.028)","(DUSP6, -0.032)","(TPTE, -0.041)","(PPM1G, -0.042)","(PTPRZ1, -0.045)","(PTPRJ, -0.069)","(KIT, -0.085)","(PPP2CB, -0.098)","(PTPN9, -0.141)"]
[742,"viral life cycle (GO:0016032)",3,0.56,0.996,0.9289,"(PARD6A, 0.733)","(CCL1, -0.086)","(GFI1, -0.27)"]
[743,"skeletal development (GO:0001501)",65,0.561,0.996,0.54135,"(PRDX1, 1.162)","(COL9A2, 0.442)","(ANXA2, 0.407)","(INHA, 0.319)","(GHRHR, 0.291)","(ARSE, 0.283)","(SOX9, 0.193)","(BMPR1B, 0.169)","(COL10A1, 0.13)","(GHR, 0.12)","(TCOF1, 0.115)","(EXTL1, 0.113)","(IGF1, 0.106)","(SHOX2, 0.1)","(PAPSS1, 0.084)","(ETS2, 0.074)","(EVC, 0.071)","(MATN3, 0.045)","(COL1A1, 0.015)","(TNFRSF11B, 0.007)","(NPR3, 0.002)","(PITX1, 0.001)","(FGFR1, 0)","(MSX2, 0)","(SPP2, 0)","(TRPS1, 0)","(MEPE, 0)","(CMKLR1, 0)","(SHOX, 0)","(PAPSS2, 0)","(TWIST1, 0)","(COL19A1, 0)","(INHBA, 0)","(IGF2, 0)","(EXT2, 0)","(HOXD13, 0)","(PTH, 0)","(FBN1, 0)","(BMPR2, 0)","(COL1A2, 0)","(BAPX1, 0)","(COL2A1, 0)","(FRZB, 0)","(PTHR1, 0)","(DLX5, 0)","(COMP, 0)","(EN1, 0)","(CHRD, 0)","(EXT1, 0)","(RPS6KA3, 0)","(LECT2, -0.008)","(TEAD4, -0.009)","(IGFBP4, -0.013)","(EBP, -0.014)","(DLL3, -0.014)","(POSTN, -0.014)","(GDF10, -0.02)","(MSX1, -0.02)","(FGFR3, -0.025)","(PRELP, -0.032)","(TBX3, -0.034)","(GDF11, -0.038)","(DLX6, -0.079)","(CALCA, -0.08)","(ALX4, -0.127)"]
[744,"MAP00400 Phenylalanine tyrosine and tryptophan biosynthesis GenMAPP",8,0.562,0.996,1,"(ENO1, 0.707)","(GOT2, 0.342)","(ENO3, 0.248)","(PAH, 0.05)","(ENO2, -0.045)","(BID, -0.178)","(GOT1, -0.189)","(TAT, -0.193)"]
[745,"tnfr1Pathway BioCarta",29,0.564,0.996,0.83198,"(TRADD, 0.702)","(DFFB, 0.414)","(CASP3, 0.31)","(JUN, 0.306)","(RB1, 0.232)","(TRAF2, 0.185)","(TNFRSF1A, 0.158)","(LMNB2, 0.081)","(PAK2, 0.052)","(LMNA, 0.04)","(PRKDC, 0.007)","(MAPK8, 0.003)","(CASP8, 0.001)","(ADPRT, 0)","(CRADD, -0.004)","(RIPK1, -0.011)","(TNF, -0.012)","(MAP3K1, -0.019)","(BAG4, -0.027)","(FADD, -0.053)","(MAP3K7, -0.057)","(LMNB1, -0.058)","(PAK1, -0.077)","(MAP2K4, -0.086)","(SPTAN1, -0.087)","(DFFA, -0.09)","(MADD, -0.159)","(ARHGDIB, -0.163)","(CASP2, -0.176)"]
[745,"L-glutamate transport (GO:0015813)",5,0.564,0.996,0.85598,"(SLC1A1, 0.62)","(SLC1A3, 0.105)","(SLC25A22, 0.004)","(SLC1A2, -0.059)","(SLC1A6, -0.184)"]
[747,"heart development (GO:0007507)",18,0.565,0.996,0.55658,"(MKKS, 0.51)","(GATA4, 0.297)","(NCOA6, 0.215)","(HAND1, 0.213)","(IRX4, 0.189)","(SHOX2, 0.159)","(ERBB2, 0.153)","(TBX1, 0.055)","(POU6F1, 0.02)","(GJA1, 0.001)","(DVL1, -0.004)","(CASQ2, -0.056)","(ECE2, -0.06)","(DVL3, -0.073)","(SRI, -0.074)","(TDGF1, -0.083)","(NKX2-5, -0.093)","(TAZ, -0.106)"]
[747,"organic cation transport (GO:0015695)",2,0.565,0.996,0.83608,"(SLC22A3, 0.17)","(SLC22A4, 0.159)"]
[747,"p53Pathway BioCarta",16,0.565,0.996,0.8772,"(RB1, 0.407)","(CCNE1, 0.369)","(TIMP3, 0.287)","(PCNA, 0.267)","(E2F1, 0.232)","(BAX, 0.146)","(BCL2, 0.043)","(ATM, 0.015)","(CCND1, 0.006)","(TP53, -0.009)","(CDK2, -0.052)","(GADD45A, -0.103)","(CDK4, -0.117)","(APAF1, -0.119)","(MDM2, -0.124)","(CDKN1A, -0.125)"]
[747,"acyl-CoA metabolism (GO:0006637)",2,0.565,0.996,0.98169,"(MLYCD, 0.182)","(CRAT, 0.04)"]
[747,"protein ubiquitination during ubiquitin-dependent protein catabolism (GO:0042787)",2,0.565,0.996,0.99077,"(RNF11, 0.432)","(SMURF1, -0.229)"]
[752,"NLS-bearing substrate import into nucleus (GO:0006607)",11,0.567,0.996,0.3365,"(KPNA2, 0.865)","(KPNA3, 0.281)","(KPNA1, 0.23)","(FYB, 0.027)","(KPNA5, 0.002)","(KPNA6, -0.046)","(CBLB, -0.08)","(KPNB1, -0.105)","(TRPS1, -0.112)","(KPNA4, -0.119)","(NCKIPSD, -0.136)"]
[752,"sarsPathway BioCarta",10,0.567,0.996,0.77746,"(ANPEP, 0.754)","(MAPK14, 0.386)","(GPT, 0.372)","(LDHB, 0.102)","(LDHC, 0.004)","(FBL, -0.025)","(EIF4E, -0.061)","(NCL, -0.087)","(CKM, -0.087)","(LDHA, -0.107)"]
[752,"GPCRs Class A Rhodopsin-like 2 GO",12,0.567,0.996,1,"(GPR68, 0.519)","(P2RX4, 0.276)","(CYSLTR1, 0.245)","(GPR45, 0.185)","(GPR161, 0.143)","(GPR34, 0.071)","(MGC29643, -0.049)","(H963, -0.072)","(CYSLTR2, -0.095)","(GPR75, -0.134)","(GPR18, -0.145)","(GPR39, -0.181)"]
[755,"tollPathway BioCarta",33,0.569,0.996,1,"(NFKBIA, 0.888)","(NFKB1, 0.737)","(SITPEC, 0.347)","(JUN, 0.332)","(IRAK1, 0.281)","(CD14, 0.276)","(MAPK14, 0.221)","(TLR4, 0.167)","(FOS, 0.096)","(TLR3, 0.021)","(MAP3K7IP1, 0.01)","(TLR2, 0.009)","(MAP3K7, 0.007)","(CHUK, -0.001)","(TRAF6, -0.005)","(PPARA, -0.007)","(MAP2K3, -0.011)","(MAPK8, -0.031)","(IKBKG, -0.043)","(MAP2K4, -0.051)","(PRKR, -0.052)","(ELK1, -0.063)","(LY96, -0.07)","(MAP3K1, -0.071)","(TOLLIP, -0.078)","(TLR6, -0.083)","(IKBKB, -0.095)","(RELA, -0.137)","(MAP3K14, -0.141)","(MAP2K6, -0.153)","(MAP3K7IP2, -0.165)","(MYD88, -0.165)","(TLR7, -0.2)"]
[756,"protein kinase C activation (GO:0007205)",8,0.57,0.996,0,"(AZU1, 0.292)","(PPAP2A, 0.258)","(PARD3, 0.184)","(DGKD, 0.115)","(PRKCABP, 0.11)","(EDN2, 0.084)","(GAP43, -0.116)","(GNB2L1, -0.171)"]
[756,"etcPathway Energy is extracted from carbohydrates via oxidation and transferred to the mitochondrial electron transport chain, which couples ATP synthesis to the reduction of oxygen to water.",9,0.57,0.996,1,"(NDUFA1, 0.412)","(SDHC, 0.233)","(SDHB, 0.191)","(GPD2, 0.182)","(CYCS, 0.126)","(SDHA, 0.109)","(ATP5A1, -0.066)","(SDHD, -0.129)","(UQCRC1, -0.19)"]
[758,"glucose transport (GO:0015758)",10,0.571,0.996,0.73805,"(SLC2A4, 0.928)","(PPBP, 0.37)","(SORBS1, 0.333)","(SLC2A1, 0.036)","(SLC2A2, 0.009)","(EDNRA, -0.002)","(INS, -0.037)","(SLC2A8, -0.148)","(SLC2A5, -0.15)","(SLC2A3, -0.158)"]
[758,"keratinocytePathway BioCarta",46,0.571,0.996,1,"(NFKBIA, 0.797)","(NFKB1, 0.556)","(MAPK13, 0.344)","(PRKCG, 0.313)","(PPP2CA, 0.238)","(JUN, 0.233)","(TRAF2, 0.198)","(TNFRSF1A, 0.168)","(PRKCE, 0.164)","(EGF, 0.152)","(MAPK14, 0.15)","(TNFSF6, 0.141)","(FOS, 0.125)","(BCL2, 0.09)","(MAPK3, 0.052)","(PRKCQ, 0.045)","(RAF1, 0.041)","(TNFRSF6, 0.031)","(EGFR, 0.008)","(HOXA7, 0.006)","(SP1, 0)","(PRKCH, 0)","(MAP2K7, 0)","(MAP2K4, 0)","(CHUK, 0)","(MAP3K5, 0)","(PRKCD, 0)","(MAPK8, 0)","(MAPK1, -0.002)","(ETS2, -0.005)","(MAP2K1, -0.011)","(MAP3K14, -0.014)","(RIPK1, -0.027)","(MAP3K1, -0.027)","(TNF, -0.027)","(MAP2K6, -0.037)","(CEBPA, -0.051)","(TNFRSF1B, -0.064)","(MAP2K3, -0.065)","(DAXX, -0.073)","(HRAS, -0.083)","(PRKCB1, -0.095)","(ETS1, -0.122)","(RELA, -0.133)","(PRKCA, -0.145)","(IKBKB, -0.148)"]
[758,"tcrMoleculePathway BLACK",5,0.571,0.996,1,"(CD3E, 0.553)","(TRA@, 0.334)","(CD3G, -0.063)","(CD3D, -0.153)","(CD3Z, -0.244)"]
[761,"neuron adhesion (GO:0007158)",2,0.572,0.996,0.93596,"(NINJ2, 0.351)","(NCAM2, -0.253)"]
[762,"MAP00510 N Glycans biosynthesis GenMAPP",17,0.574,0.998,0.36047,"(B4GALT5, 0.58)","(FUT8, 0.326)","(MGAT2, 0.276)","(MAN2A1, 0.272)","(ALG5, 0.192)","(MGAT3, 0.122)","(DPM1, 0.109)","(B4GALT2, 0.082)","(B4GALT3, 0.066)","(B4GALT1, 0.049)","(DPAGT1, -0.033)","(MGAT1, -0.055)","(FLJ21924, -0.139)","(DDOST, -0.145)","(SIAT1, -0.178)","(PPOX, -0.179)","(GCS1, -0.219)"]
[762,"regulation of synaptic plasticity (GO:0048167)",2,0.574,0.998,0.91715,"(UBA52, 0.149)","(YWHAH, 0.068)"]
[762,"acetaminophenPathway Acetaminophen selectively inhibits Cox-3, which is localized to the brain, and yields the toxic metabolite NAPQI when processed by CAR in the liver.",5,0.574,0.998,0.92328,"(CYP2E1, 1.086)","(CYP1A2, -0.059)","(NR1I3, -0.116)","(PTGS2, -0.22)","(PTGS1, -0.235)"]
[765,"positive regulation of peptidyl-tyrosine phosphorylation (GO:0050731)",3,0.575,0.998,0.92297,"(CD81, 0.398)","(TDGF1, 0.162)","(CD80, -0.087)"]
[766,"gcrPathway BioCarta",18,0.576,0.998,0.99727,"(NFKB1, 0.939)","(GNAS, 0.542)","(ANXA1, 0.366)","(ADRB2, 0.187)","(NR3C1, 0.119)","(GNB1, 0.086)","(CALM1, 0.037)","(PIK3R1, -0.039)","(CALM2, -0.047)","(NPPA, -0.049)","(PIK3CA, -0.072)","(HSPCA, -0.093)","(CALM3, -0.128)","(NOS3, -0.141)","(SYT1, -0.145)","(AKT1, -0.156)","(RELA, -0.181)","(GNGT1, -0.2)"]
[767,"argininecPathway Related catabolic pathways process arginine, histidine, glutamine, and proline through glutamate to alpha-ketoglutamate, which feeds into the citric acid cycle.",6,0.578,1,0.88646,"(PRODH, 0.499)","(ALDH4A1, 0.083)","(GLS, 0.08)","(OAT, 0.054)","(GLUD1, -0.061)","(ARG1, -0.11)"]
[767,"glycogen catabolism (GO:0005980)",4,0.578,1,0.88651,"(PHKB, 0.75)","(PYGB, 0.157)","(GAA, -0.257)","(PHKA1, -0.263)"]
[767,"botulinPathway BLACK",4,0.578,1,0.93877,"(STX1A, 0.292)","(SNAP25, 0.174)","(CHRNA1, -0.012)","(VAMP2, -0.073)"]
[767,"protein retention in ER (GO:0006621)",2,0.578,1,1,"(PDIA3, 0.002)","(PDIA2, -0.001)"]
[771,"proteolysis (GO:0006508)",77,0.58,1,0.72183,"(FBXO2, 0.465)","(IDE, 0.362)","(SHFM1, 0.324)","(UBE3A, 0.272)","(DF, 0.252)","(WFDC2, 0.213)","(ZMPSTE24, 0.209)","(PLAT, 0.198)","(DEFB126, 0.197)","(CTSF, 0.191)","(CAPN3, 0.17)","(BLMH, 0.161)","(PHEX, 0.134)","(RNPEP, 0.13)","(CTSG, 0.121)","(CPA3, 0.102)","(REN, 0.086)","(KLKB1, 0.082)","(TMPRSS6, 0.011)","(PSMB9, 0.01)","(CASP1, 0.009)","(P11, 0.007)","(CASP5, 0.006)","(TPP2, 0.004)","(USP25, 0)","(NEDD8, 0)","(PSMC2, 0)","(UBE1C, 0)","(CASP2, 0)","(MBTPS1, 0)","(ST14, 0)","(HGFAC, 0)","(PCSK5, 0)","(MME, 0)","(LNPEP, 0)","(CASP6, 0)","(PLAU, 0)","(VHL, 0)","(RCE1, 0)","(CASP4, 0)","(CTSS, 0)","(CTRC, 0)","(CTSZ, 0)","(CTSH, 0)","(MMP14, 0)","(CASP8, 0)","(PREP, 0)","(C9orf3, 0)","(ELA3A, 0)","(ADAMTS5, 0)","(PMPCA, 0)","(FURIN, 0)","(CTSK, 0)","(PCSK1, 0)","(PGC, 0)","(F2, 0)","(FBXO3, 0)","(LCN1, 0)","(PSMB10, 0)","(CPA1, 0)","(PSMC4, 0)","(MMP20, 0)","(FBXL6, 0)","(CORIN, 0)","(DPP3, 0)","(ACE, 0)","(PSMB8, 0)","(SPG7, 0)","(CTRL, 0)","(MMP12, -0.008)","(FBXL2, -0.009)","(SIAH1, -0.01)","(PCSK2, -0.015)","(CTSB, -0.02)","(CTSO, -0.045)","(MMP24, -0.137)","(FBXO5, -0.154)"]
[772,"GLYCOGEN Manually Curated",20,0.581,1,0.73339,"(GYG, 0.483)","(GYG2, 0.373)","(AGL, 0.203)","(GSK3B, 0.189)","(PYGL, 0.148)","(PHKA2, 0.113)","(PPP1CB, 0.103)","(GYS2, 0.086)","(PPP1R3A, 0.082)","(PPP1CC, 0.052)","(PYGM, 0.023)","(GBE1, -0.013)","(GCKR, -0.014)","(PPP1R2, -0.034)","(G6PC, -0.054)","(GYS1, -0.077)","(GAA, -0.087)","(KIAA1026, -0.089)","(SLC37A4, -0.096)","(PPP1CA, -0.117)"]
[773,"akapCentrosomePathway Anchoring protein AKAP350 keeps protein kinase A bound to the centrosome during interphase.",14,0.582,1,1,"(PPP2CA, 0.388)","(PRKCE, 0.25)","(PRKAR2A, 0.234)","(PRKACB, 0.226)","(PRKAR2B, 0.201)","(PCNT2, 0.149)","(PCNT1, 0.123)","(PRKCL1, -0.071)","(PRKACG, -0.073)","(PRKAG1, -0.074)","(PPP1CA, -0.082)","(CDC2, -0.089)","(MAP2, -0.151)","(AKAP9, -0.169)"]
[774,"protein export from nucleus (GO:0006611)",2,0.583,1,0.99198,"(XPO7, 0.601)","(CALR, -0.368)"]
[774,"GLUCOSE DOWN Peng at al 2002",149,0.583,1,1,"(MAGED1, 0.671)","(FUS, 0.414)","(HLF, 0.288)","(C1orf8, 0.284)","(RPLP2, 0.264)","(SF3A3, 0.224)","(UCHL1, 0.223)","(TRAF5, 0.218)","(SFN, 0.218)","(SLC12A4, 0.218)","(CAPZA1, 0.209)","(HEAB, 0.204)","(ELL, 0.204)","(RAB9A, 0.204)","(ATP6V0B, 0.198)","(UBE2N, 0.197)","(TEGT, 0.196)","(MKI67, 0.175)","(DPYSL2, 0.162)","(SMC4L1, 0.148)","(FOLR1, 0.131)","(RB1, 0.13)","(NMU, 0.115)","(MRPS18B, 0.113)","(MAD2L1, 0.089)","(G3BP, 0.084)","(BAZ1A, 0.027)","(BPAG1, 0.015)","(PSMA5, 0.008)","(GC20, 0.007)","(DKK4, 0)","(FZR1, 0)","(EIF2B4, 0)","(ELMO1, 0)","(ATP5J, 0)","(PHB, 0)","(ILK, 0)","(SLA, 0)","(CALM1, 0)","(SSTR5, 0)","(DAPK2, 0)","(AGL, 0)","(RAP1A, 0)","(TNNT1, 0)","(ARPC5, 0)","(PRKCBP1, 0)","(ADCYAP1, 0)","(TERF2, 0)","(BMP1, 0)","(MSH2, 0)","(SCN4A, 0)","(NUP98, 0)","(ID2, 0)","(POLG, 0)","(ITGB7, 0)","(NAP1L1, 0)","(MYCN, 0)","(CCNG1, 0)","(KIAA0284, 0)","(SFRS1, 0)","(RAB1A, 0)","(EIF3S3, 0)","(PPP2R5A, 0)","(PTGER3, 0)","(GCDH, 0)","(MAP4, 0)","(WBSCR1, 0)","(ARTN, 0)","(RAB2, 0)","(HIP1R, 0)","(CD47, 0)","(ASF1A, 0)","(DVL3, 0)","(ADNP, 0)","(CDC2, 0)","(AAMP, 0)","(SFRS2, 0)","(ATP2A2, 0)","(ARF4, 0)","(DYRK1A, 0)","(ERAL1, 0)","(GTF2A2, 0)","(VNN2, 0)","(RRBP1, 0)","(NFYB, 0)","(POGZ, 0)","(IFI16, 0)","(DKFZP547E1010, 0)","(USP33, 0)","(FUBP1, 0)","(EHD1, 0)","(ESPL1, 0)","(GABARAP, 0)","(TIMM17A, 0)","(SH2B, 0)","(GJB5, 0)","(MGC8721, 0)","(ABO, 0)","(ECE2, 0)","(SSBP1, 0)","(DNAJA1, 0)","(BCL2, 0)","(PDCD4, 0)","(BFSP2, 0)","(RNF6, 0)","(PAPSS1, 0)","(ACK1, 0)","(MICB, 0)","(CREM, 0)","(COMT, 0)","(SIAT4C, 0)","(DEK, 0)","(USP12, 0)","(SLC25A5, 0)","(KIAA1093, 0)","(MTVR1, 0)","(HTR1B, 0)","(EDG4, 0)","(CCT4, 0)","(CD86, 0)","(RAB31, 0)","(E2F4, 0)","(TUBB5, 0)","(WEE1, 0)","(RANBP2, 0)","(ARHGEF6, 0)","(PICALM, 0)","(PRKCABP, 0)","(GORASP2, 0)","(RBBP4, 0)","(SMC5L1, 0)","(TXNIP, 0)","(E2F1, 0)","(KIF11, 0)","(XRCC5, 0)","(HNRPR, 0)","(SEC24C, 0)","(DNAJB6, 0)","(RPA3, 0)","(CDC7, 0)","(GPR3, 0)","(RAB5A, 0)","(MYEF2, 0)","(ZFR, 0)","(AF1Q, 0)","(GMPR, 0)","(FOSL2, 0)","(OIP5, 0)","(STK6, 0)"]
[776,"regulation of epidermal growth factor receptor activity (GO:0007176)",2,0.584,1,1,"(NCK2, 0.199)","(SHC1, -0.045)"]
[777,"ST GRANULE CELL SURVIVAL PATHWAY Signalling Transduction KE",28,0.585,1,1,"(CAMP, 0.709)","(JUN, 0.387)","(CASP3, 0.358)","(CREB3, 0.334)","(CREB1, 0.291)","(DAG1, 0.16)","(MAPK8IP2, 0.147)","(FOS, 0.125)","(ADPRT, 0.124)","(MAPK8IP1, 0.092)","(MAPK1, 0.027)","(EPHB2, -0.004)","(ASAH1, -0.006)","(MAP2K4, -0.019)","(ITPKA, -0.021)","(MAPK8, -0.024)","(APC, -0.05)","(CREB5, -0.066)","(PACAP, -0.069)","(CXCL2, -0.083)","(GNAQ, -0.107)","(ITPKB, -0.117)","(MAPK10, -0.118)","(MAPK9, -0.126)","(MAP2K7, -0.129)","(IL8RB, -0.13)","(CERK, -0.141)","(MAPK8IP3, -0.147)"]
[778,"chemosensory behavior (GO:0007635)",2,0.586,1,0.95406,"(CASR, 0.218)","(TAS2R1, -0.06)"]
[778,"muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway (GO:0007197)",2,0.586,1,0.9619,"(CHRM2, 0.244)","(CHRM5, -0.009)"]
[780,"vitamin A metabolism (GO:0006776)",4,0.588,1,0.99981,"(RBP1, 0.222)","(RLBP1, 0.203)","(ALDH1A2, 0.069)","(RPE65, -0.144)"]
[780,"MAP00062 Fatty acid biosynthesis path 2 GenMAPP",7,0.588,1,1,"(HADHA, 0.517)","(HADHB, 0.18)","(ECHS1, 0.155)","(ACAA1, -0.03)","(ACAA2, -0.151)","(ACAT1, -0.165)","(EHHADH, -0.196)",{"$nulls":109},"(YARS, 0)","(CSNK1G2, 0)","(LAPTM5, 0)","(CDKN1A, 0)","(PNOC, 0)"]
[782,"gamma-aminobutyric acid signaling pathway (GO:0007214)",9,0.589,1,0.9553,"(GABBR1, 0.464)","(GABRA1, 0.361)","(GABRA3, 0.276)","(GABRB2, 0.07)","(GABRA4, 0.066)","(GABRR1, -0.044)","(GABRA2, -0.062)","(GABRE, -0.071)","(GABRG2, -0.152)"]
[782,"telPathway BioCarta",18,0.589,1,1,"(TNKS, 0.542)","(RB1, 0.352)","(PPP2CA, 0.33)","(TERT, 0.217)","(TERF1, 0.167)","(G22P1, 0.131)","(BCL2, 0.096)","(MYC, 0.05)","(EGFR, 0.033)","(POLR2A, 0.019)","(TP53, -0.022)","(TEP1, -0.025)","(XRCC5, -0.086)","(AKT1, -0.111)","(HSPCA, -0.113)","(IGF1R, -0.117)","(KRAS2, -0.128)","(PRKCA, -0.131)"]
[782,"amino sugar metabolism (GO:0006040)",2,0.589,1,1,"(ST3GAL6, 0.001)","(ST3GAL2, 0)"]
[785,"cell surface receptor linked signal transduction Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.",139,0.59,1,0.72205,"(BAG1, 0.354)","(IGSF2, 0.331)","(PLCG2, 0.331)","(CLEC2, 0.312)","(CSF3, 0.231)","(IL6R, 0.213)","(NTSR2, 0.212)","(IL12RB1, 0.209)","(BIRC3, 0.204)","(TNFRSF14, 0.204)","(STC2, 0.2)","(ADMR, 0.2)","(INHA, 0.185)","(TTRAP, 0.172)","(IL12RB2, 0.134)","(IL8RA, 0.131)","(ANXA1, 0.129)","(MAPK14, 0.124)","(SAG, 0.095)","(KLRB1, 0.085)","(CCR1, 0.05)","(CD14, 0.007)","(FLNA, 0)","(DOK1, 0)","(STC1, 0)","(PIP5K2B, 0)","(ASGR2, 0)","(AGER, 0)","(DRD4, 0)","(C21orf4, 0)","(LILRB2, 0)","(OXTR, 0)","(TRPV1, 0)","(DOK2, 0)","(PTPRC, 0)","(RAMP2, 0)","(8D6A, 0)","(CCL2, 0)","(BIRC2, 0)","(CCL25, 0)","(KLRF1, 0)","(GALR2, 0)","(TNFRSF10B, 0)","(GEM, 0)","(IFNG, 0)","(CTF1, 0)","(HRAS, 0)","(KLRD1, 0)","(RAMP3, 0)","(MERTK, 0)","(MKNK2, 0)","(BRD8, 0)","(LLT1, 0)","(FLJ38628, 0)","(LILRB3, 0)","(TACSTD2, 0)","(CCR5, 0)","(CHRM4, 0)","(KLRA1, 0)","(ARHGEF2, 0)","(CD160, 0)","(GLRA2, 0)","(KLRG1, 0)","(OSMR, 0)","(IL8RB, 0)","(ADCYAP1R1, 0)","(BAIAP1, 0)","(INS, 0)","(CXCL10, 0)","(IFNAR2, 0)","(IL7R, 0)","(MARCO, 0)","(MYD88, 0)","(CLC, 0)","(ADRB2, 0)","(RRAGA, 0)","(LILRB1, 0)","(AGT, 0)","(LY6E, 0)","(IL18RAP, 0)","(HRMT1L2, 0)","(IFNAR1, 0)","(EDNRB, 0)","(CD97, 0)","(CENTA1, 0)","(IL1R1, 0)","(IL6, 0)","(CD28, 0)","(SIRPB1, 0)","(IFNA2, 0)","(GIPR, 0)","(PDGFRA, 0)","(TACR3, 0)","(NPR2, 0)","(ECGF1, 0)","(HGF, 0)","(IL6ST, 0)","(IFNGR2, 0)","(CLEC1, 0)","(AGTR2, 0)","(IL2RA, 0)","(GLRB, 0)","(PRKCA, 0)","(IL13RA1, 0)","(IFNB1, 0)","(MADD, 0)","(TNFRSF13B, 0)","(CD79A, 0)","(BDKRB2, 0)","(SSTR1, 0)","(MS4A3, 0)","(SST, 0)","(CD19, 0)","(C5, 0)","(GLRA1, 0)","(LIF, 0)"]
[786,"regulation of blood coagulation (GO:0030193)",2,0.591,1,0.92507,"(F2, 0.073)","(GP1BA, -0.051)"]
[787,"bile acid transport (GO:0015721)",2,0.592,1,0.91306,"(AKR1C4, 0.389)","(ATP8B1, -0.315)"]
[787,"gpcrPathway BioCarta",34,0.592,1,1,"(GNAS, 0.477)","(PLCG1, 0.448)","(CREB1, 0.34)","(JUN, 0.332)","(NFATC1, 0.273)","(PRKAR2A, 0.148)","(PRKACB, 0.138)","(NFATC3, 0.137)","(PPP3CC, 0.121)","(PRKAR1B, 0.111)","(ADCY1, 0.109)","(FOS, 0.098)","(PRKAR2B, 0.094)","(MAPK3, 0.063)","(RAF1, 0.047)","(PPP3CA, 0.03)","(CALM1, 0.019)","(GNAI1, 0)","(MAP2K1, -0.01)","(CALM2, -0.019)","(SYT1, -0.023)","(GNB1, -0.033)","(PRKCB1, -0.035)","(PRKCA, -0.05)","(NFATC4, -0.053)","(HRAS, -0.054)","(GNAQ, -0.066)","(ELK1, -0.082)","(RPS6KA3, -0.088)","(PRKACG, -0.09)","(CALM3, -0.105)","(PRKAR1A, -0.127)","(PPP3CB, -0.186)","(GNGT1, -0.218)"]
[789,"igf1mtorPathway BioCarta",20,0.593,1,0.95694,"(RPS6KB1, 0.698)","(PPP2CA, 0.323)","(EIF2S2, 0.273)","(EIF2B5, 0.271)","(IGF1, 0.192)","(GSK3B, 0.176)","(INPPL1, 0.147)","(PDPK1, 0.141)","(FRAP1, 0.054)","(PDK2, -0.005)","(IGF1R, -0.013)","(RPS6, -0.056)","(PIK3R1, -0.073)","(PIK3CA, -0.078)","(EIF4E, -0.094)","(PTEN, -0.098)","(EIF2S1, -0.116)","(AKT1, -0.14)","(EIF2S3, -0.167)","(EIF4EBP1, -0.18)"]
[790,"hormone-mediated signaling (GO:0009755)",3,0.594,1,0.74988,"(ADIPOR1, 0.509)","(ADIPOR2, 0.347)","(LATS1, -0.465)"]
[790,"mapkPathway BioCarta",86,0.594,1,0.94168,"(NFKBIA, 0.608)","(NFKB1, 0.487)","(TRADD, 0.416)","(RPS6KB1, 0.342)","(MAPK13, 0.275)","(MAPK11, 0.269)","(ATF2, 0.2)","(CREB1, 0.198)","(JUN, 0.194)","(MAP4K4, 0.14)","(RAC1, 0.138)","(ARAF1, 0.11)","(MAP4K3, 0.107)","(RPS6KA5, 0.107)","(RPS6KA2, 0.105)","(MAP3K9, 0.094)","(MAP3K2, 0.09)","(MAPKAPK3, 0.079)","(BRAF, 0.02)","(MAPK14, 0.019)","(MAPK6, 0)","(MAP3K10, 0)","(TGFB2, 0)","(MAP3K7, 0)","(RPS6KA3, 0)","(MAP2K6, 0)","(RELA, 0)","(RPS6KA4, 0)","(MEF2D, 0)","(MAP3K13, 0)","(MAP4K1, 0)","(MAP3K8, 0)","(MAP3K11, 0)","(TGFBR1, 0)","(MAP2K7, 0)","(MYC, 0)","(MEF2B, 0)","(TRAF2, 0)","(MAP3K1, 0)","(MKNK1, 0)","(RPS6KB2, 0)","(GRB2, 0)","(HRAS, 0)","(MAPK7, 0)","(MAP3K14, 0)","(TGFB3, 0)","(MKNK2, 0)","(MAP3K5, 0)","(MAP2K2, 0)","(MAPK10, 0)","(MEF2A, 0)","(RPS6KA1, 0)","(DAXX, 0)","(TGFB1, 0)","(MAPK8, 0)","(MAX, 0)","(SP1, 0)","(MAP3K3, 0)","(MAP3K6, 0)","(MAPK3, 0)","(MAP4K5, 0)","(MAPK4, 0)","(IKBKB, 0)","(PAK1, 0)","(RIPK1, 0)","(CEBPA, 0)","(MAP2K1, 0)","(SHC1, 0)","(MAPKAPK5, 0)","(RAF1, 0)","(MAP2K4, 0)","(MAP4K2, 0)","(MEF2C, 0)","(MAP2K3, 0)","(MAPK9, 0)","(STAT1, 0)","(MAP3K4, 0)","(MAPKAPK2, 0)","(MAP3K12, 0)","(MAPK1, 0)","(PAK2, 0)","(FOS, 0)","(MAP2K5, 0)","(ELK1, 0)","(MAPK12, -0.02)","(CHUK, -0.056)"]
[792,"positive regulation of cell proliferation (GO:0008284)",90,0.595,1,0.57377,"(TIMP1, 0.814)","(TNFSF13, 0.423)","(IL9, 0.331)","(IL12RB1, 0.307)","(CSF3, 0.289)","(PTK2B, 0.272)","(ADRA2A, 0.269)","(VEGFB, 0.258)","(TBC1D8, 0.18)","(TGFBR2, 0.17)","(BCL6, 0.164)","(IL12RB2, 0.142)","(CSF1, 0.123)","(EGF, 0.105)","(CD81, 0.098)","(SSR1, 0.085)","(CD86, 0.073)","(IGF1, 0.039)","(IL6, 0.019)","(ALOX12, 0.013)","(CDC25B, 0.008)","(FGA, 0.004)","(MST1R, 0)","(IL5, 0)","(RHOG, 0)","(GRN, 0)","(STIM1, 0)","(DHPS, 0)","(NAP1L1, 0)","(GLP2R, 0)","(EDN1, 0)","(TCIRG1, 0)","(VEGF, 0)","(IL11, 0)","(PTN, 0)","(SLAMF1, 0)","(CDC2L5, 0)","(FLT3, 0)","(IRS2, 0)","(SHC1, 0)","(FGF2, 0)","(PTHLH, 0)","(TNFSF4, 0)","(TNFRSF11A, 0)","(FGB, 0)","(CTF1, 0)","(VEGFC, 0)","(FIGF, 0)","(CXCL10, 0)","(EDG5, 0)","(CAPNS1, 0)","(FGF18, 0)","(HOXC10, 0)","(IGF1R, 0)","(NOL1, 0)","(CCKBR, 0)","(CDK2, 0)","(CXCL5, 0)","(NRP1, 0)","(IL3, 0)","(TDGF1, 0)","(CUL3, 0)","(LRP5, 0)","(VIPR1, 0)","(DNAJA2, 0)","(FGF7, 0)","(FLT3LG, 0)","(CCL14, 0)","(HTR1A, 0)","(ADRA1D, 0)","(TSHR, 0)","(PBEF1, 0)","(IL7, 0)","(FLT1, 0)","(MATK, 0)","(PRTN3, 0)","(FGG, 0)","(BTC, 0)","(BNC1, 0)","(TTK, 0)","(CAPN1, 0)","(UBE2C, 0)","(REG1A, 0)","(FOSL1, 0)","(PGF, 0)","(FGF4, 0)","(LIF, -0.007)","(IL15, -0.056)","(VIP, -0.073)","(EGR4, -0.079)"]
[792,"CR CELL CYCLE PNAS 2004",82,0.595,1,1,"(NPM1, 0.309)","(CKS2, 0.292)","(BUB3, 0.288)","(SKP1A, 0.249)","(CDC14A, 0.204)","(RBL1, 0.189)","(RB1, 0.181)","(CDC27, 0.178)","(NUMA1, 0.159)","(GAS1, 0.147)","(MXI1, 0.145)","(CHES1, 0.129)","(CCNH, 0.111)","(MAD2L1, 0.108)","(CDKN1B, 0.102)","(CDC37, 0.098)","(CDK8, 0.095)","(ERH, 0.093)","(GADD45B, 0.086)","(CCNE1, 0.079)","(CCND1, 0.045)","(CDC25B, 0.04)","(FRK, 0.027)","(CHEK1, 0.017)","(MYC, 0.015)","(CDC20, 0.015)","(TP53, 0.013)","(ZW10, 0.009)","(CDKN1C, 0.008)","(ORC1L, 0.007)","(GAS2, 0.006)","(CDC2L5, 0)","(E2F2, 0)","(HUS1, 0)","(CKS1B, 0)","(CENPE, 0)","(CDK6, 0)","(BTG2, 0)","(MYBL2, 0)","(POLR3D, 0)","(CENPC1, 0)","(CDC16, 0)","(CDC6, 0)","(CDC42, 0)","(CDC25A, 0)","(CDK7, 0)","(CDK2, 0)","(TP73, 0)","(TFDP2, 0)","(BUB1B, 0)","(CDKN2A, 0)","(DDX11, 0)","(CCNE2, 0)","(CDKN2B, 0)","(CDC45L, 0)","(MAX, 0)","(CENPA, 0)","(CCND2, 0)","(CDC25C, 0)","(BCCIP, 0)","(SKP2, 0)","(TTK, 0)","(MAD1L1, 0)","(MNAT1, 0)","(CENPF, 0)","(MAD, 0)","(E2F1, 0)","(BUB1, 0)","(CCNA2, 0)","(CCNF, 0)","(CDC7, 0)","(CDC2, 0)","(CDC2L1, 0)","(CDK4, 0)","(CCNB1, 0)","(MOS, 0)","(CCND3, 0)","(CDKN1A, 0)","(CDK5, 0)","(MDM2, -0.008)","(GSPT1, -0.013)","(FOSL1, -0.087)"]
[794,"regulation of transcription, DNA-dependent (GO:0006355)",71,0.596,1,0.57528,"(ADH7, 1.027)","(HDAC5, 0.332)","(HSF4, 0.227)","(POU6F2, 0.211)","(NME2, 0.204)","(ZNF274, 0.2)","(RPS6KA5, 0.19)","(HCLS1, 0.18)","(CARM1, 0.176)","(BCL6, 0.157)","(ZNF263, 0.157)","(CTNNBIP1, 0.143)","(VPS4B, 0.122)","(NR2C2, 0.112)","(ZNF278, 0.107)","(HDAC4, 0.101)","(ATRX, 0.096)","(ATBF1, 0.081)","(LMX1B, 0.045)","(CRABP2, 0.03)","(SLC2A4RG, 0.012)","(CALR, 0)","(ZNF42, 0)","(SP100, 0)","(RPS6KA4, 0)","(CREBBP, 0)","(NFYB, 0)","(HIC1, 0)","(ABL1, 0)","(ELAVL2, 0)","(NFKB2, 0)","(ESR2, 0)","(ZNF74, 0)","(NFYA, 0)","(HOXD13, 0)","(LIMD1, 0)","(PRDM16, 0)","(ZNF282, 0)","(TCFL5, 0)","(SMARCA3, 0)","(HMGA1, 0)","(TP53, 0)","(PDCD11, 0)","(ZNF45, 0)","(ATF4, 0)","(TNF, 0)","(NR1D2, 0)","(SCAND1, 0)","(TRIM22, 0)","(SMAD1, 0)","(CXXC1, 0)","(ZNF146, 0)","(PREB, 0)","(UBE2V1, 0)","(AHR, 0)","(ZNF35, 0)","(GATA6, 0)","(DDIT3, 0)","(HDAC2, 0)","(TBX21, 0)","(PFDN5, -0.001)","(TMF1, -0.004)","(SCRT1, -0.008)","(RPL6, -0.014)","(EZH2, -0.014)","(MEN1, -0.02)","(NOTCH2, -0.023)","(JMJD1C, -0.031)","(SMAD5, -0.072)","(RORB, -0.081)","(HMGA2, -0.092)"]
[794,"G-protein coupled receptor protein signaling pathway (GO:0007186)",132,0.596,1,0.62781,"(C3, 0.876)","(ADRA2B, 0.319)","(GPR109B, 0.295)","(GNAZ, 0.284)","(AKAP12, 0.232)","(F2RL1, 0.215)","(GPR35, 0.213)","(ADORA2B, 0.209)","(ADRA2A, 0.202)","(PYY, 0.196)","(GPSM2, 0.196)","(PTGER2, 0.186)","(CCRL1, 0.178)","(ADRA1B, 0.161)","(GPR68, 0.149)","(PDC, 0.136)","(CCL17, 0.118)","(IL8RA, 0.076)","(CD3E, 0.071)","(CXCL12, 0.053)","(GPR43, 0.038)","(ADRB2, 0.019)","(MLNR, 0.015)","(PIK3CB, 0.008)","(CCL3, 0)","(GNA12, 0)","(FSHR, 0)","(TBXA2R, 0)","(GPR51, 0)","(FPRL1, 0)","(AVPR1A, 0)","(GPR32, 0)","(PTGER3, 0)","(EDG1, 0)","(SPHK1, 0)","(EDG6, 0)","(PTGER1, 0)","(ADRA1A, 0)","(OR1D4, 0)","(BLR1, 0)","(LANCL1, 0)","(GPR21, 0)","(C3AR1, 0)","(C5, 0)","(ARHGEF11, 0)","(RHO, 0)","(GPR75, 0)","(HTR5A, 0)","(GPR30, 0)","(GRM1, 0)","(CCL23, 0)","(EDG5, 0)","(GPR37, 0)","(CALM3, 0)","(GHSR, 0)","(CHRM3, 0)","(ENPP2, 0)","(CXCL9, 0)","(GPR19, 0)","(PTAFR, 0)","(GPR20, 0)","(GRPR, 0)","(UCN, 0)","(TRHR, 0)","(PTHR2, 0)","(PTH, 0)","(CXCL3, 0)","(MS4A2, 0)","(GPR15, 0)","(EDG2, 0)","(CASR, 0)","(PIK3CG, 0)","(TAS2R1, 0)","(CRHR1, 0)","(PTPN6, 0)","(ADRA2C, 0)","(GNB3, 0)","(CCR9, 0)","(SCTR, 0)","(EBI2, 0)","(PPYR1, 0)","(EDG4, 0)","(CCR8, 0)","(GPR65, 0)","(CXCL2, 0)","(TGM2, 0)","(FPR1, 0)","(GPR12, 0)","(CXCR6, 0)","(GPRC5C, 0)","(RRH, 0)","(OPN3, 0)","(NPY5R, 0)","(IL8, 0)","(GNRHR, 0)","(MAS1, 0)","(GPR25, 0)","(MLN, 0)","(GPR39, 0)","(GPR17, 0)","(HTR1A, 0)","(ADRA1D, 0)","(GPR50, 0)","(GPR4, 0)","(GPR22, 0)","(RAPGEF4, 0)","(VIP, 0)","(GNAI2, 0)","(BDKRB2, 0)","(OPN1MW, 0)","(AVPR1B, 0)","(OR10J1, 0)","(GPR31, 0)","(CX3CR1, 0)","(GPR52, 0)","(GPR44, 0)"]
[796,"antimicrobial humoral response (sensu Vertebrata) (GO:0019735)",69,0.598,1,0.56433,"(FCN2, 0.552)","(IL12RB1, 0.386)","(DEFA5, 0.344)","(CD22, 0.243)","(MAPK11, 0.211)","(XCR1, 0.207)","(CCR6, 0.189)","(CCL20, 0.165)","(CCL22, 0.154)","(CCL3, 0.13)","(ITGB2, 0.108)","(KLRC1, 0.102)","(IL7R, 0.1)","(KLRD1, 0.098)","(KLRF1, 0.098)","(CCL16, 0.092)","(GRAP2, 0.09)","(MGST2, 0.085)","(CD53, 0.06)","(MAPK14, 0.037)","(IL12B, 0.029)","(MGST3, 0.002)","(PTGES, 0)","(ADAR, 0)","(CLC, 0)","(CD2BP2, 0)","(SLAMF1, 0)","(BATF, 0)","(CD58, 0)","(CXCR3, 0)","(ADA, 0)","(CSF1R, 0)","(CD226, 0)","(CSF2RB, 0)","(YY1, 0)","(NR4A2, 0)","(PTAFR, 0)","(CRLF1, 0)","(LILRB2, 0)","(SFTPD, 0)","(XCL1, 0)","(CD1C, 0)","(MASP2, 0)","(CCR2, 0)","(IL1B, 0)","(HHEX, 0)","(IL26, 0)","(CCL15, 0)","(CCL18, 0)","(LCN1, 0)","(DEFA6, 0)","(IL13, 0)","(CRIP1, 0)","(APS, 0)","(LTB4R2, 0)","(DNTT, 0)","(BLM, 0)","(TNFRSF17, -0.004)","(FADD, -0.007)","(CD72, -0.008)","(GBX2, -0.01)","(ALCAM, -0.016)","(UBD, -0.02)","(CYBB, -0.032)","(CCL7, -0.055)","(CCR7, -0.07)","(ENTPD1, -0.091)","(CD1B, -0.101)","(KLRC4, -0.138)"]
[797,"intercellular junction assembly (GO:0007043)",5,0.599,1,0.99636,"(TJP1, 0.364)","(GJA5, 0.196)","(GJA4, 0.05)","(GJA7, 0.04)","(PARD6B, -0.143)"]
[798,"ephA4Pathway Eph kinases are receptor tyrosine kinases that bind surface-expressed ephrin ligands and are active in neuronal development and platelet aggregation.",10,0.6,1,0.87206,"(SELP, 0.352)","(FYN, 0.329)","(EPHA4, 0.225)","(ACTA1, 0.184)","(EPHB1, 0.139)","(LYN, 0.047)","(ITGB1, 0.009)","(L1CAM, -0.121)","(RAP1B, -0.142)","(ITGA1, -0.259)"]
[798,"T-helper 1 type immune response (GO:0042088)",4,0.6,1,0.98288,"(EBI3, 0.428)","(SPP1, 0.245)","(IL18BP, 0.07)","(TLR6, -0.235)"]
[800,"T cell activation (GO:0042110)",6,0.601,1,0.99843,"(CD86, 0.52)","(NCK1, 0.248)","(CD80, 0.022)","(CD2, -0.046)","(CD7, -0.085)","(CD3D, -0.194)"]
[800,"CR CYTOSKELETON PNAS 2005",25,0.601,1,1,"(MUC1, 0.248)","(MCF2, 0.241)","(BPAG1, 0.206)","(SPTB, 0.198)","(FLNA, 0.158)","(RSN, 0.151)","(VCL, 0.147)","(CETN1, 0.125)","(SPTA1, 0.121)","(PFN1, 0.074)","(VIM, 0.06)","(EMS1, 0.036)","(TTN, 0.035)","(MAPT, 0)","(MYL3, -0.015)","(MAP1B, -0.022)","(PTCH, -0.034)","(MYL2, -0.035)","(TUBA1, -0.04)","(TLN1, -0.077)","(TUBA2, -0.086)","(KISS1, -0.115)","(MSN, -0.121)","(ACTG1, -0.136)","(GSN, -0.143)"]
[802,"sex determination (GO:0007530)",3,0.602,1,0.94826,"(AMH, 0.31)","(DMRT1, -0.025)","(NR0B1, -0.094)"]
[802,"ST Integrin Signaling Pathway Signalling Transduction KE",77,0.602,1,1,"(ITGA6, 0.838)","(PLCG2, 0.406)","(AKT2, 0.39)","(PLCG1, 0.316)","(CRK, 0.301)","(MYLK, 0.192)","(PIK3CB, 0.151)","(P4HB, 0.147)","(MAPK8IP2, 0.121)","(PKLR, 0.111)","(WAS, 0.11)","(VASP, 0.101)","(ITGA7, 0.098)","(GRB7, 0.096)","(SOS2, 0.079)","(GRLF1, 0.077)","(ILK, 0.065)","(ARHGEF6, 0.052)","(FYN, 0.026)","(MAPK8IP1, 0.021)","(ITGA10, 0.016)","(RALA, 0.015)","(MRAS, 0.01)","(ANGPTL2, 0)","(PAK3, 0)","(ITGA4, 0)","(PAK6, 0)","(MAP3K11, 0)","(ITGA5, 0)","(TERF2IP, 0)","(ACTR2, 0)","(MAP2K7, 0)","(ABL1, 0)","(EPHB2, 0)","(CDC42, 0)","(PTK2, 0)","(MAPK8IP3, 0)","(GRB2, 0)","(ITGA3, 0)","(ROCK1, 0)","(PIK3CA, 0)","(ACK1, 0)","(CDKN2A, 0)","(MAPK10, 0)","(TLN1, 0)","(SRC, 0)","(ITGA1, 0)","(MAPK8, 0)","(PAK4, 0)","(ARHGEF7, 0)","(ITGA2, 0)","(ITGB3BP, 0)","(ITGA8, 0)","(SOS1, 0)","(RHO, 0)","(ACTN1, 0)","(PAK1, 0)","(CSE1L, 0)","(SHC1, 0)","(RAF1, 0)","(ACTR3, 0)","(MAP2K4, 0)","(BRAF, 0)","(MAPK9, 0)","(PAK7, 0)","(ZYX, 0)","(ROCK2, 0)","(DOCK1, 0)","(MAPK1, 0)","(PAK2, 0)","(ITGA9, 0)","(TLN2, 0)","(PTEN, 0)","(CAV1, -0.007)","(AKT3, -0.015)","(DDEF1, -0.017)","(AKT1, -0.033)"]
[804,"MAP00252 Alanine and aspartate metabolism GenMAPP",21,0.603,1,0.89268,"(GAD1, 0.541)","(ABAT, 0.224)","(GPT, 0.204)","(GOT2, 0.146)","(AGXT, 0.122)","(CAD, 0.109)","(NARS, 0.103)","(ASS, 0.1)","(CRAT, 0.096)","(ASPA, 0.076)","(DARS, 0.075)","(ADSS, -0.008)","(ASNS, -0.029)","(DDO, -0.035)","(ASL, -0.046)","(ADSL, -0.066)","(GOT1, -0.1)","(DDX3X, -0.111)","(PC, -0.127)","(AARS, -0.151)","(GAD2, -0.167)"]
[805,"methioninePathway BLACK",5,0.604,1,0.4485,"(MUT, 0.683)","(BCKDHB, 0.104)","(CBS, -0.11)","(BCKDK, -0.172)","(CTH, -0.257)"]
[805,"MAP00310 Lysine degradation GenMAPP",17,0.604,1,0.48197,"(ALDH2, 0.612)","(SHMT1, 0.574)","(HADHA, 0.335)","(PLOD, 0.199)","(AASS, 0.07)","(ECHS1, 0.06)","(BBOX1, 0.038)","(GCDH, 0.037)","(LOC56901, -0.032)","(OGDH, -0.039)","(ALDH3A2, -0.039)","(ACAT1, -0.063)","(ALDH1A1, -0.084)","(ALDH1B1, -0.102)","(DLST, -0.153)","(EHHADH, -0.162)","(SHMT2, -0.23)"]
[805,"regulation of cell shape (GO:0008360)",3,0.604,1,0.94397,"(FGD6, 0.218)","(FGD2, 0.078)","(FGD1, 0.055)"]
[805,"phospholipid biosynthesis (GO:0008654)",2,0.604,1,0.98532,"(DGKE, 0.416)","(PCYT2, -0.244)"]
[809,"apoptotic program (GO:0008632)",9,0.605,1,0.92371,"(VDAC1, 0.802)","(MCL1, 0.283)","(BIK, 0.154)","(BAD, 0.051)","(CASP7, 0.03)","(CASP8, 0.006)","(CASP9, -0.089)","(CASP2, -0.146)","(PSEN2, -0.18)"]
[809,"binding of sperm to zona pellucida (GO:0007339)",2,0.605,1,0.94319,"(ZP2, 0.497)","(SPAM1, -0.164)"]
[809,"CR PROTEIN MOD PNAS 2010",150,0.605,1,1,"(PTPRM, 0.574)","(UCHL3, 0.322)","(PTPRH, 0.296)","(RPS6KB1, 0.29)","(PPP4C, 0.27)","(DUSP3, 0.231)","(FES, 0.229)","(HDAC5, 0.218)","(ANPEP, 0.213)","(PTPN4, 0.211)","(USP4, 0.2)","(PRKCG, 0.186)","(UBE2N, 0.16)","(CTSD, 0.156)","(PTPN3, 0.156)","(PIM1, 0.155)","(IL3RA, 0.153)","(PTPRG, 0.082)","(HDAC4, 0.026)","(RPS6KA2, 0.026)","(PPP1R3A, 0.008)","(CUL1, 0.007)","(PDK2, 0)","(PRKCL1, 0)","(PTPRC, 0)","(PRKG1, 0)","(NAT2, 0)","(RYK, 0)","(PRKACG, 0)","(MME, 0)","(HCK, 0)","(PRKCZ, 0)","(EP300, 0)","(PDPK1, 0)","(TESK1, 0)","(PPP2R3A, 0)","(PRKCL2, 0)","(PTPRD, 0)","(PTPN12, 0)","(ABL2, 0)","(PIK3CA, 0)","(BLK, 0)","(PTPN6, 0)","(PTPRF, 0)","(PTPRK, 0)","(HDAC6, 0)","(PRKAG1, 0)","(PPEF1, 0)","(DUSP8, 0)","(HPN, 0)","(PTPN7, 0)","(PPP1CC, 0)","(TBCC, 0)","(PRKCB1, 0)","(LTK, 0)","(PRKAR1A, 0)","(PTK9, 0)","(LIMK1, 0)","(PPP2R5A, 0)","(ACP5, 0)","(SIAT1, 0)","(PTPN9, 0)","(PTP4A1, 0)","(RAGE, 0)","(CSNK1E, 0)","(LYN, 0)","(PTP4A2, 0)","(STK11, 0)","(CSNK2A2, 0)","(USP6, 0)","(PPP2CA, 0)","(DUSP7, 0)","(PAK2, 0)","(MATK, 0)","(USP5, 0)","(LIMK2, 0)","(PRKCI, 0)","(PPM1D, 0)","(ST13, 0)","(PTPN18, 0)","(FURIN, 0)","(YES1, 0)","(LCK, 0)","(CTSB, 0)","(PRKR, 0)","(FER, 0)","(FGR, 0)","(DPP4, 0)","(PTPRR, 0)","(PRKACA, 0)","(PRSS25, 0)","(BMX, 0)","(PRKDC, 0)","(ABL1, 0)","(PRKACB, 0)","(CHUK, 0)","(PRKCA, 0)","(PPP1CB, 0)","(DUSP9, 0)","(PHKG2, 0)","(TMPRSS2, 0)","(PAPSS1, 0)","(VHL, 0)","(PRKAR1B, 0)","(PRKCM, 0)","(DUSP5, 0)","(DMPK, 0)","(PPP2R4, 0)","(PTK7, 0)","(PDK4, 0)","(PTPN11, 0)","(CSNK2B, 0)","(PPP2R1B, 0)","(PRKAR2B, 0)","(PTPN2, 0)","(CUL2, 0)","(ELK3, 0)","(PTPRZ1, 0)","(PTPN1, 0)","(PTPN13, 0)","(ACPP, 0)","(CSNK1D, 0)","(BCR, 0)","(PPP3CA, 0)","(PRKCQ, 0)","(PPP5C, 0)","(PPP3CB, 0)","(DUSP4, 0)","(KIT, 0)","(STK3, 0)","(ACP2, 0)","(PPP2R2A, 0)","(PPP2R5D, 0)","(STK4, 0)","(PPP6C, 0)","(ACP1, 0)","(PTPRB, 0)","(PPP1CA, 0)","(SKI, 0)","(PTPRN2, 0)","(CSNK1A1, 0)","(PRKG2, 0)","(PPP2R5E, 0)","(PTPRN, 0)","(UBE2I, 0)","(PTPRA, 0)","(ELK1, 0)","(PCAF, 0)","(PHKA2, 0)","(PPP2R5B, 0)"]
[812,"MAP00280 Valine leucine and isoleucine degradation GenMAPP",26,0.606,1,0.80381,"(HMGCS2, 0.595)","(ALDH2, 0.5)","(MUT, 0.303)","(HMGCS1, 0.256)","(HADHA, 0.184)","(MCCC2, 0.098)","(HADHB, 0.087)","(C14orf45, 0.078)","(PCCA, 0.062)","(ECHS1, 0.06)","(BCKDHB, -0.001)","(HMGCL, -0.012)","(ALDH1A1, -0.017)","(BCKDHA, -0.019)","(ACADM, -0.03)","(ALDH3A2, -0.049)","(ACAA1, -0.068)","(MCCC1, -0.068)","(PCCB, -0.069)","(AOX1, -0.071)","(ACAA2, -0.073)","(ALDH1B1, -0.082)","(ACADS, -0.084)","(ALDH6A1, -0.095)","(EHHADH, -0.099)","(IVD, -0.144)"]
[813,"caspasePathway Caspases are cysteine proteases active in apoptosis; caspase-8 and 9 cleave and activate other caspases, while 3, 6, and 7 cleave cellular targets.",23,0.607,1,0.55226,"(DFFB, 0.49)","(CASP3, 0.378)","(BIRC3, 0.373)","(BIRC2, 0.246)","(BIRC4, 0.17)","(CASP6, 0.096)","(CASP1, 0.077)","(LMNA, 0.073)","(ADPRT, 0.073)","(CASP10, 0.069)","(LMNB2, 0.069)","(GZMB, 0.062)","(LMNB1, 0.037)","(CASP7, 0.025)","(CYCS, 0.019)","(CASP4, 0.014)","(DFFA, 0.012)","(CASP8, -0.003)","(APAF1, -0.026)","(ARHGDIB, -0.064)","(CASP9, -0.12)","(CASP2, -0.128)","(PRF1, -0.159)"]
[813,"glycosphingolipid biosynthesis (GO:0006688)",3,0.607,1,0.88526,"(UGT8, 0.404)","(UGCG, 0.136)","(LARGE, -0.369)"]
[813,"DNA replication, synthesis of RNA primer (GO:0006269)",3,0.607,1,0.91859,"(PRIM2A, 0.356)","(PRIM1, 0.1)","(POLRMT, -0.136)"]
[816,"BRCA DOWN Welcsh et al 2002",13,0.609,1,1,"(RXRA, 0.713)","(GCN5L2, 0.365)","(SLC19A1, 0.155)","(HSF1, 0.045)","(C11orf13, 0.018)","(MYC, 0.013)","(CCND1, 0)","(NDRG1, -0.003)","(EIF4G1, -0.092)","(CHD4, -0.111)","(BOP1, -0.119)","(SKIV2L, -0.15)","(NUP214, -0.206)"]
[816,"cblPathway Activated EGF receptors undergo endocytosis into clathrin-coated vesicles, where they are recycled to the membrane or ubiquitinated by Cbl.",12,0.609,1,1,"(MET, 0.647)","(EGF, 0.315)","(SH3GLB1, 0.279)","(GRB2, 0.068)","(CBL, 0.013)","(SRC, 0.003)","(SH3GLB2, -0.015)","(EGFR, -0.045)","(PRKCB1, -0.063)","(PDGFRA, -0.08)","(PRKCA, -0.131)","(CSF1R, -0.23)"]
[818,"SA PTEN PATHWAY SigmaAldrich",17,0.61,1,0.48565,"(AKT2, 0.758)","(PTK2B, 0.61)","(RBL2, 0.231)","(MAPK3, 0.08)","(PDK1, 0.043)","(ILK, 0.033)","(PIP3-E, 0.003)","(SHC1, -0.01)","(AKT3, -0.028)","(SOS1, -0.033)","(BPNT1, -0.033)","(GRB2, -0.038)","(MAPK1, -0.04)","(PIK3CA, -0.091)","(AKT1, -0.121)","(PTEN, -0.157)","(PIK3CD, -0.182)"]
[818,"regulation of Cdc42 GTPase activity (GO:0043088)",3,0.61,1,0.94397,"(FGD6, 0.193)","(FGD1, 0.093)","(FGD2, 0.059)"]
[820,"akap13Pathway A-kinase anchor protein 13 (AKAP13) localizes protein kinase A holoenzyme and is a nucleotide exchange factor for Rho/Rac.",10,0.614,1,0.88308,"(PRKACB, 0.307)","(PRKAR2A, 0.302)","(PRKAR2B, 0.162)","(EDG7, 0.129)","(AKAP13, 0.126)","(GNA12, 0.088)","(EDG4, 0.062)","(PRKAG1, -0.021)","(EDG2, -0.044)","(PRKACG, -0.182)"]
[820,"rRNA processing (GO:0006364)",11,0.614,1,0.98905,"(RNU3IP2, 0.757)","(POP4, 0.291)","(GEMIN4, 0.222)","(FBL, 0.045)","(PDCD11, -0.032)","(EXOSC2, -0.035)","(NOLC1, -0.042)","(NOL5A, -0.101)","(DKC1, -0.12)","(EXOSC7, -0.166)","(KIAA1008, -0.249)"]
[822,"ox40Pathway BLACK",3,0.615,1,0.91264,"(TNFSF4, 0.306)","(TNFRSF4, 0.158)","(IL2, -0.219)"]
[822,"regulation of vasoconstriction (GO:0019229)",2,0.615,1,0.92024,"(KCNMB2, 0.478)","(KCNMB4, -0.373)"]
[822,"regulation of glycolysis (GO:0006110)",2,0.615,1,0.94056,"(PFKM, 0.381)","(HSGT1, -0.431)"]
[825,"positive regulation of tumor necrosis factor-alpha biosynthesis (GO:0042535)",2,0.616,1,0.76842,"(AZU1, 0.451)","(TLR1, -0.28)"]
[826,"positive regulation of actin filament polymerization (GO:0030838)",3,0.617,1,1,"(NCK1, 0.309)","(NCK2, 0.027)","(ARF6, -0.062)"]
[826,"oxygen and reactive oxygen species metabolism (GO:0006800)",2,0.617,1,1,"(SFTPD, 0.199)","(AOX1, -0.159)"]
[826,"tcytotoxicPathway BioCarta",13,0.617,1,1,"(CD3E, 0.397)","(CD28, 0.328)","(ITGB2, 0.219)","(TRA@, 0.203)","(ITGAL, 0.053)","(THY1, 0.022)","(CD2, -0.032)","(PTPRC, -0.038)","(CD3G, -0.056)","(ICAM1, -0.065)","(CD8A, -0.129)","(CD3D, -0.142)","(CD3Z, -0.195)"]
[829,"wntPathway BioCarta",25,0.618,1,0.89923,"(TLE1, 0.852)","(TCF1, 0.327)","(PPP2CA, 0.228)","(FRAT1, 0.184)","(GSK3B, 0.162)","(PPARD, 0.116)","(HDAC1, 0.111)","(BTRC, 0.102)","(AXIN1, 0.099)","(WIF1, 0.077)","(MAP3K7IP1, 0.067)","(DVL1, 0.03)","(MYC, 0.026)","(FZD1, 0.003)","(APC, 0)","(CTNNB1, 0)","(CSNK1A1, -0.013)","(MAP3K7, -0.045)","(CREBBP, -0.059)","(CSNK2A1, -0.061)","(CCND1, -0.071)","(WNT1, -0.085)","(CTBP1, -0.109)","(CSNK1D, -0.149)","(NLK, -0.152)"]
[830,"induction of apoptosis by intracellular signals (GO:0008629)",6,0.619,1,0.99403,"(CUL1, 0.485)","(CUL3, 0.448)","(CUL5, 0.013)","(CDKN1A, -0.117)","(CUL2, -0.159)","(CUL4A, -0.193)"]
[831,"ribosome biogenesis (GO:0007046)",2,0.62,1,0.92881,"(NOL6, 0.304)","(DDX54, -0.232)"]
[831,"DOWNREG BY HOXA9 Manually Curated",32,0.62,1,0.97437,"(GATA2, 0.516)","(FCGRT, 0.448)","(JUN, 0.36)","(ARNTL, 0.323)","(DSIPI, 0.161)","(SDCBP, 0.158)","(CDC37, 0.123)","(GLRX, 0.117)","(KRT18, 0.058)","(SRP72, 0.044)","(VHL, 0.028)","(SBNO1, 0.021)","(SERPINB9, 0.021)","(CISH, 0.015)","(MYC, 0.007)","(HBE1, 0.005)","(DCT, 0.003)","(SDC4, 0.002)","(RBBP6, 0)","(DNCLI2, 0)","(BMI1, -0.027)","(LYN, -0.038)","(TPR, -0.043)","(IGF2, -0.064)","(FXR1, -0.094)","(OSBPL8, -0.1)","(SFRS11, -0.102)","(JUNB, -0.106)","(CLCN7, -0.138)","(WSB1, -0.144)","(CD36, -0.168)","(MAN2A2, -0.185)"]
[833,"dcPathway Dendritic cells internalize and present antigen, after which they migrate to lymphocyte-rich tissues and induce T and B cell differentiation.",21,0.621,1,1,"(ANPEP, 0.56)","(IL12A, 0.279)","(TLR4, 0.215)","(CSF2, 0.123)","(IL12B, 0.11)","(ITGAX, 0.109)","(TNFRSF5, 0.108)","(CD5, 0.097)","(IL10, 0.092)","(IL3, 0.075)","(CD33, 0.066)","(IL13, 0.005)","(IL5, -0.012)","(IFNB1, -0.014)","(IFNA1, -0.025)","(TLR2, -0.031)","(IFNG, -0.043)","(CD7, -0.044)","(CD2, -0.044)","(TLR7, -0.098)","(IL4, -0.107)"]
[834,"phosphate metabolism (GO:0006796)",15,0.622,1,0.52614,"(IMPA2, 1.265)","(ACYP1, 0.264)","(ENPP3, 0.193)","(SLC17A2, 0.166)","(PTPRB, 0.023)","(IMPA1, 0.018)","(PP, -0.005)","(ENPP2, -0.005)","(ACYP2, -0.047)","(ENPP1, -0.066)","(SLC17A3, -0.069)","(INPP1, -0.095)","(SYNJ1, -0.112)","(SLC34A1, -0.169)","(PTPRS, -0.248)"]
[834,"protein targeting to membrane (GO:0006612)",3,0.622,1,0.93748,"(PRKCI, 0.501)","(SEC63, 0.051)","(ICMT, -0.237)"]
[834,"aspartate catabolism (GO:0006533)",4,0.622,1,0.98373,"(GOT2, 0.527)","(ASPA, 0.173)","(DDO, -0.207)","(GOT1, -0.21)"]
[837,"cellcyclePathway Cyclins interact with cyclin-dependent kinases to form active kinase complexes that regulate progression through the cell cycle.",23,0.623,1,0.82332,"(CDKN2C, 0.337)","(RB1, 0.293)","(RBL1, 0.277)","(CDKN1B, 0.254)","(CCNE1, 0.236)","(E2F1, 0.163)","(CCNH, 0.123)","(CCNA1, 0.077)","(CDK6, 0.076)","(CCND2, 0.069)","(CDC25A, -0.003)","(CDC2, -0.005)","(CCND3, -0.02)","(CCND1, -0.028)","(CDK2, -0.049)","(CDKN2D, -0.052)","(CDK7, -0.055)","(CCNB1, -0.067)","(CDKN1A, -0.072)","(CDKN2A, -0.09)","(TFDP1, -0.12)","(CDKN2B, -0.139)","(CDK4, -0.182)"]
[837,"cytoskeletal anchoring (GO:0007016)",5,0.623,1,0.96923,"(FLNB, 0.714)","(SPTBN4, -0.039)","(PLEC1, -0.067)","(RDX, -0.123)","(VIL2, -0.137)"]
[839,"feeding behavior (GO:0007631)",17,0.625,1,0.72427,"(MC4R, 0.656)","(AGRP, 0.344)","(PYY, 0.252)","(FYN, 0.247)","(NPY, 0.164)","(NPY2R, 0.09)","(PMCH, 0.02)","(NPY1R, 0.016)","(CCKBR, -0.007)","(GALR2, -0.014)","(HCRTR1, -0.056)","(PPYR1, -0.059)","(GCG, -0.062)","(CCKAR, -0.091)","(HCRTR2, -0.137)","(GPR24, -0.158)","(HTR2C, -0.201)"]
[839,"transcription initiation (GO:0006352)",3,0.625,1,0.88921,"(SMARCA5, 0.626)","(HBXAP, -0.231)","(GTF2H2, -0.269)"]
[839,"hcmvPathway BioCarta",16,0.625,1,0.98675,"(NFKB1, 0.943)","(RB1, 0.409)","(CREB1, 0.394)","(MAPK14, 0.352)","(MAPK3, 0.054)","(MAP2K2, 0.054)","(PIK3R1, 0.028)","(MAP2K1, -0.03)","(MAP2K3, -0.034)","(MAPK1, -0.034)","(AKT1, -0.129)","(MAP2K6, -0.131)","(MAP3K1, -0.156)","(SP1, -0.167)","(PIK3CA, -0.177)","(RELA, -0.215)"]
[839,"extrinsicPathway The extrinsic prothrombin activation pathway requires the release of thromboplastin from damaged tissues to activate the blood clotting cascade.",13,0.625,1,1,"(PROS1, 1.045)","(F5, 0.433)","(FGA, 0.19)","(F7, 0.171)","(F2, 0.024)","(FGG, 0)","(F10, -0.002)","(FGB, -0.01)","(F2R, -0.086)","(F3, -0.118)","(SERPINC1, -0.157)","(PROC, -0.177)","(TFPI, -0.183)"]
[843,"mismatch repair (GO:0006298)",11,0.627,1,0.86021,"(MLH1, 0.274)","(MSH2, 0.267)","(TREX1, 0.255)","(MSH5, 0.208)","(TP73, 0.147)","(PMS2, 0.127)","(MSH3, -0.03)","(MUTYH, -0.045)","(ABL1, -0.063)","(MSH6, -0.169)","(PMS1, -0.214)"]
[843,"lymphocyte chemotaxis (GO:0048247)",3,0.627,1,0.96407,"(SAA1, 0.583)","(CKLF, -0.178)","(DOCK2, -0.272)"]
[845,"regulation of transcription from RNA polymerase I promoter (GO:0006356)",3,0.628,1,0.99262,"(TFAM, 0.277)","(POLR2K, 0.028)","(UBTF, -0.039)"]
[846,"MAP00271 Methionine metabolism GenMAPP",8,0.629,1,0.86867,"(DNMT1, 0.478)","(MAT1A, 0.404)","(MTR, 0.026)","(MARS, 0.003)","(BHMT, -0.021)","(CBS, -0.083)","(AHCY, -0.122)","(CTH, -0.16)"]
[847,"HEMO TF LIST JP Manually Curated",86,0.63,1,0,"(NOTCH1, 0.428)","(NFKB1, 0.427)","(PAX8, 0.389)","(PHC1, 0.32)","(GATA2, 0.311)","(HIF1A, 0.302)","(JUN, 0.243)","(LMO2, 0.222)","(PBX1, 0.213)","(MLL, 0.204)","(CEBPE, 0.204)","(NFIX, 0.201)","(SRF, 0.186)","(HOXA10, 0.167)","(KLF1, 0.155)","(NFIC, 0.143)","(SPI1, 0.143)","(DLX4, 0.142)","(TFAP2A, 0.138)","(KLF3, 0.111)","(EPAS1, 0.089)","(CEBPB, 0.071)","(NFE2, 0.064)","(NFYA, 0.046)","(GATA3, 0.035)","(PAX6, 0.018)","(E2F2, 0)","(LHX2, 0)","(FLI1, 0)","(HHEX, 0)","(MEIS1, 0)","(WT1, 0)","(HLX1, 0)","(FOXD3, 0)","(HOXC6, 0)","(MAFB, 0)","(EGR1, 0)","(GFI1, 0)","(HOXA5, 0)","(ZNFN1A1, 0)","(NFIB, 0)","(MYC, 0)","(ETS1, 0)","(EP300, 0)","(TCF3, 0)","(MYB, 0)","(HOXD13, 0)","(MAFK, 0)","(GBX2, 0)","(ELF1, 0)","(TAL1, 0)","(NF1, 0)","(GATA1, 0)","(KLF13, 0)","(HMGB3, 0)","(TFAP4, 0)","(BMP4, 0)","(HOXB3, 0)","(CREBBP, 0)","(POU1F1, 0)","(STAT5A, 0)","(IRF1, 0)","(RUNX1, 0)","(ETV6, 0)","(PRRX1, 0)","(SP3, 0)","(CEBPA, 0)","(ETS2, 0)","(NFKB2, 0)","(STAT3, 0)","(ETV4, 0)","(ZNF42, 0)","(E2F1, 0)","(EED, 0)","(BMI1, 0)","(USF2, 0)","(HOXA7, 0)","(MEFV, 0)","(HOXD3, 0)","(STAT1, 0)","(HOXA9, 0)","(PAX5, 0)","(POU2F1, 0)","(HOXB6, 0)","(XBP1, 0)","(HOXB8, -0.044)"]
[847,"malatePathway BLACK",4,0.63,1,1,"(MDH1, 0.292)","(SLC1A3, 0.155)","(SLC25A11, 0.033)","(GOT1, -0.25)"]
[847,"MAP00602 Blood group glycolipid biosynthesis neolact series GenMAPP",14,0.63,1,1,"(FUT3, 0.643)","(B4GALT5, 0.609)","(FUT6, 0.197)","(GCNT2, 0.103)","(B4GALT2, 0.082)","(B4GALT1, 0.039)","(FUT2, -0.033)","(ABO, -0.051)","(B4GALT3, -0.058)","(FUT1, -0.077)","(B3GNT1, -0.13)","(FUT5, -0.147)","(PPOX, -0.152)","(SIAT1, -0.169)"]
[850,"MAP00720 Reductive carboxylate cycle CO2 fixation GenMAPP",7,0.631,1,0.75814,"(IDH1, 0.871)","(MDH1, 0.237)","(IDH2, -0.018)","(ACO2, -0.191)","(ACO1, -0.248)","(MDH2, -0.264)","(FH, -0.274)"]
[851,"fibrinolysis (GO:0042730)",3,0.633,1,0.94982,"(GP1BA, 0.044)","(F2, 0.044)","(TMPRSS6, -0.033)"]
[851,"MAP00272 Cysteine metabolism GenMAPP",9,0.633,1,1,"(GOT2, 0.32)","(MPST, 0.274)","(CARS, 0.23)","(LDHB, 0.069)","(SDS, 0.059)","(LDHC, -0.016)","(LDHA, -0.042)","(GOT1, -0.119)","(CTH, -0.177)"]
[853,"ST Wnt Ca2 cyclic GMP Pathway Signalling Transduction KE",19,0.634,1,0.98516,"(PDE6D, 0.547)","(PDE6G, 0.42)","(PDE6A, 0.362)","(PDE6B, 0.332)","(DAG1, 0.151)","(BF, 0.09)","(CAMK2A, 0.062)","(ITPKA, 0.054)","(ITPR3, 0.016)","(ITPR1, 0.011)","(CAMK2G, -0.001)","(CAMK2B, -0.007)","(ITPR2, -0.076)","(ITPKB, -0.088)","(NFAT5, -0.1)","(PDE6C, -0.105)","(SLC6A13, -0.123)","(TF, -0.136)","(PDE6H, -0.19)"]
[854,"positive regulation of gluconeogenesis (GO:0045722)",3,0.635,1,0.89127,"(PPARGC1A, 0.2)","(ARPP-19, 0.094)","(PRKAA1, -0.242)"]
[855,"SMAD protein heteromerization (GO:0007183)",2,0.636,1,0.96551,"(SMAD4, 0.192)","(ZFYVE9, -0.119)"]
[856,"STAT protein nuclear translocation (GO:0007262)",3,0.637,1,0.91893,"(STAT1, 0.144)","(F2R, 0.07)","(F2, 0.069)"]
[856,"embryonic development (sensu Mammalia) (GO:0001701)",7,0.637,1,0.99657,"(ADAM10, 0.374)","(NCOA6, 0.271)","(FOXD3, 0.268)","(MBNL1, 0.042)","(PTPRR, -0.066)","(DLL3, -0.093)","(ARNT2, -0.208)"]
[858,"calcium-mediated signaling (GO:0019722)",6,0.638,1,0.99748,"(BTK, 0.688)","(SPHK1, 0.132)","(PIP5K3, 0.1)","(IL8, -0.062)","(CAMKK2, -0.063)","(LAT, -0.128)"]
[859,"monocytePathway BioCarta",11,0.64,1,1,"(SELE, 0.468)","(SELP, 0.355)","(ITGB2, 0.244)","(ITGA4, 0.152)","(ITGAL, 0.129)","(ITGAM, 0.103)","(ITGB1, 0.009)","(ICAM1, -0.148)","(CD44, -0.179)","(PECAM1, -0.205)","(SELL, -0.258)"]
[859,"autophagy (GO:0006914)",4,0.64,1,1,"(ATG4A, 0.002)","(ATG3, 0)","(ATG12, 0)","(ATG4B, 0)"]
[861,"nfatPathway BioCarta",52,0.641,1,1,"(RPS6KB1, 0.453)","(NFATC1, 0.206)","(CAMK1G, 0.194)","(MYH2, 0.184)","(PPP3CC, 0.158)","(GATA4, 0.154)","(GSK3B, 0.151)","(NFATC3, 0.151)","(MAPK14, 0.144)","(PRKAR2A, 0.133)","(HAND1, 0.119)","(FKBP1A, 0.104)","(IGF1, 0.088)","(ACTA1, 0.087)","(MAPK3, 0.08)","(PPP3CA, 0.079)","(PRKACB, 0.073)","(PRKAR2B, 0.042)","(AGT, 0.008)","(RAF1, 0.006)","(CALM1, 0)","(PRKACG, 0)","(PIK3R1, 0)","(CALM3, 0)","(CTF1, 0)","(PRKAR1B, 0)","(NKX2-5, 0)","(F2, 0)","(FGF2, 0)","(HAND2, 0)","(NPPA, 0)","(CAMK4, 0)","(CSNK1A1, 0)","(ELSPBP1, 0)","(CALR, -0.005)","(MAPK1, -0.006)","(DTR, -0.019)","(CAMK1, -0.02)","(PPP3CB, -0.029)","(PIK3CA, -0.032)","(LIF, -0.032)","(NFATC4, -0.039)","(MAP2K1, -0.042)","(EDN1, -0.05)","(CALM2, -0.051)","(SYT1, -0.071)","(CREBBP, -0.073)","(HRAS, -0.097)","(AKT1, -0.1)","(MAPK8, -0.121)","(MEF2C, -0.155)","(PRKAR1A, -0.155)"]
[861,"protein amino acid autophosphorylation (GO:0046777)",7,0.641,1,1,"(TAF1, 0.868)","(MAP3K9, 0.275)","(CAMKK2, -0.025)","(MAP3K12, -0.036)","(MAP3K10, -0.163)","(TNK1, -0.171)","(CRK7, -0.248)"]
[863,"erkPathway Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway.",30,0.642,1,0.90871,"(GNAS, 0.469)","(KLK2, 0.369)","(RPS6KA5, 0.263)","(PPP2CA, 0.247)","(RPS6KA1, 0.1)","(DPM2, 0.072)","(MAPK3, 0.066)","(NGFR, 0.048)","(SOS1, 0.042)","(MAP2K2, 0.039)","(MKNK2, 0.029)","(PDGFRA, 0.021)","(ITGB1, 0.005)","(EGFR, 0)","(MYC, 0)","(GNB1, 0)","(GRB2, -0.005)","(MKNK1, -0.009)","(PTPRR, -0.026)","(RAF1, -0.028)","(MAP2K1, -0.029)","(IGF1R, -0.042)","(HRAS, -0.053)","(SRC, -0.058)","(SHC1, -0.063)","(ELK1, -0.074)","(MAPK1, -0.107)","(NGFB, -0.113)","(STAT3, -0.124)","(GNGT1, -0.145)"]
[864,"respiratory gaseous exchange (GO:0007585)",13,0.643,1,0.82152,"(COX5B, 0.36)","(ELN, 0.299)","(CYSLTR1, 0.15)","(UCP3, 0.134)","(HNMT, 0.078)","(TBXA2R, 0.03)","(EDNRA, 0.023)","(BPGM, 0.004)","(COX15, -0.008)","(CSF2RB, -0.03)","(CFTR, -0.134)","(COX11, -0.178)","(SFTPB, -0.186)"]
[865,"ossification (GO:0001503)",10,0.645,1,0.78036,"(OSTF1, 0.448)","(SPP1, 0.268)","(STATH, 0.217)","(DSPP, 0.165)","(RUNX2, 0.054)","(CASR, 0)","(MGP, -0.107)","(CALCR, -0.122)","(SPARC, -0.13)","(DMP1, -0.236)"]
[865,"caspase activation (GO:0006919)",6,0.645,1,1,"(BBC3, 0.315)","(BCL2L10, 0.193)","(COL4A3, 0.093)","(STAT1, 0.086)","(F2R, 0.03)","(F2, 0.002)"]
[865,"GATA1 WEISS Weiss et al 2003",24,0.645,1,1,"(MAFG, 0.692)","(UROS, 0.468)","(KLF1, 0.325)","(HEBP2, 0.213)","(MAFK, 0.181)","(TFRC, 0.138)","(HMBS, 0.098)","(FTL, 0.08)","(NFE2, 0.064)","(GSTT2, 0.056)","(ANK1, -0.002)","(MAFF, -0.006)","(EPB49, -0.026)","(SLC12A5, -0.034)","(TFR2, -0.055)","(HBA2, -0.071)","(SERPINI1, -0.086)","(HBB, -0.086)","(MAFB, -0.093)","(BACH1, -0.095)","(GYPA, -0.099)","(HEBP1, -0.143)","(HBZ, -0.144)","(PPOX, -0.162)"]
[868,"ndkDynaminPathway BioCarta",18,0.646,1,0.82722,"(BIN1, 0.405)","(NME2, 0.384)","(EPS15, 0.32)","(PPP3CC, 0.232)","(AMPH, 0.16)","(AP2M1, 0.038)","(NME1, 0.006)","(PPP3CA, 0.003)","(EPN1, -0.001)","(CALM1, -0.02)","(CALM2, -0.038)","(PICALM, -0.05)","(SYT1, -0.093)","(SYNJ1, -0.1)","(CALM3, -0.118)","(PPP3CB, -0.137)","(DNM1, -0.222)","(SYNJ2, -0.222)"]
[868,"dopamine receptor, adenylate cyclase activating pathway (GO:0007191)",2,0.646,1,0.92117,"(DRD1, 0.259)","(DRD5, -0.223)"]
[868,"regulation of mitosis (GO:0007088)",10,0.646,1,0.93421,"(NEK2, 0.376)","(TERF1, 0.284)","(CDC2L5, 0.147)","(PKMYT1, 0.084)","(SKB1, 0.016)","(YWHAH, -0.012)","(CDC16, -0.023)","(PIN1, -0.138)","(CENPF, -0.191)","(CDC25C, -0.194)"]
[868,"vasculogenesis (GO:0001570)",4,0.646,1,0.98899,"(CUL7, 0.442)","(EGFL7, 0.12)","(VEGF, 0.006)","(GLMN, -0.135)"]
[868,"FRASOR ER UP Frasor et al 2004",32,0.646,1,1,"(TFF1, 0.91)","(EPB41L3, 0.453)","(ADCY9, 0.313)","(CXCL12, 0.195)","(AP1G1, 0.162)","(FOS, 0.144)","(SLC39A6, 0.086)","(SIAH2, 0.069)","(GLRB, 0.063)","(GREB1, 0.051)","(AREG, 0.04)","(RFC4, 0.028)","(WISP2, 0.017)","(CA12, 0.015)","(C11orf8, 0.007)","(SDC2, 0.007)","(SLC22A5, 0.005)","(MAPT, 0)","(IGFBP4, -0.014)","(RET, -0.019)","(TOP2A, -0.038)","(PEG10, -0.051)","(CALCR, -0.054)","(EGR3, -0.065)","(RASGRP1, -0.095)","(MYBL1, -0.096)","(PDZK1, -0.108)","(RAB31, -0.119)","(NRIP1, -0.131)","(PTGES, -0.142)","(CDC6, -0.149)","(SPUVE, -0.16)"]
[873,"oocyte axis determination (GO:0007309)",2,0.647,1,1,"(AXIN1, 0.001)","(LEFTY2, -0.001)"]
[874,"RNA elongation from RNA polymerase II promoter (GO:0006368)",6,0.648,1,0.96624,"(ELL, 0.65)","(ELL2, 0.257)","(ELL3, 0.008)","(TCEB2, -0.122)","(GTF2F2, -0.212)","(CDK9, -0.227)"]
[874,"ctlPathway Cytotoxic T lymphocytes induce apoptosis in infected cells presenting antigen-MHC-I complexes via the perforin and Fas/Fas ligand pathways.",14,0.648,1,1,"(HLA-A, 0.366)","(CD3E, 0.35)","(ITGB2, 0.294)","(TRA@, 0.259)","(ITGAL, 0.166)","(TNFRSF6, 0.106)","(TNFSF6, 0.06)","(GZMB, 0.008)","(ICAM1, -0.046)","(CD3G, -0.084)","(PRF1, -0.093)","(CD3D, -0.145)","(CD3Z, -0.148)","(B2M, -0.176)"]
[876,"spermatogenesis (GO:0007283)",62,0.649,1,0.85514,"(JAG2, 0.739)","(PTCH2, 0.441)","(WFDC2, 0.273)","(HOXA10, 0.243)","(RFP, 0.225)","(SPA17, 0.207)","(PTTG1, 0.188)","(TESK1, 0.168)","(DMC1, 0.149)","(SPAG4, 0.146)","(FOXJ1, 0.126)","(OR7A5, 0.119)","(RPL39L, 0.098)","(REC8L1, 0.094)","(CRISP3, 0.086)","(CCNA1, 0.086)","(TESK2, 0.081)","(PNMA1, 0.047)","(BCL2L10, 0.027)","(HSF2BP, 0.026)","(OAZ3, 0.024)","(INSL3, 0.011)","(YBX2, 0)","(SPAG11, 0)","(FSHPRH1, 0)","(HIST1H1T, 0)","(BRD2, 0)","(GPR64, 0)","(SYCP1, 0)","(DEDD, 0)","(NASP, 0)","(CDYL, 0)","(NR6A1, 0)","(TCFL5, 0)","(PRM1, 0)","(TSPY1, 0)","(CRISP1, 0)","(PRM2, 0)","(SPO11, 0)","(DUSP13, 0)","(BCL2L2, 0)","(ADAM28, 0)","(ADAM29, 0)","(DNAH9, 0)","(CCT6B, 0)","(ABCB9, 0)","(RPL10L, 0)","(PRKACG, 0)","(NME5, 0)","(HIST1H1A, -0.007)","(ADAM18, -0.011)","(RUVBL1, -0.016)","(SOX30, -0.028)","(MTL5, -0.031)","(WNT1, -0.041)","(FSHR, -0.042)","(RBMY1A1, -0.048)","(CDY1, -0.06)","(LIG3, -0.065)","(DAZAP1, -0.071)","(PRKAG1, -0.08)","(USP9Y, -0.107)"]
[877,"FA Manually Curated",22,0.651,1,0.73785,"(ACADVL, 0.42)","(HADHA, 0.303)","(DCI, 0.25)","(CPT1B, 0.194)","(HADHSC, 0.135)","(384D8-2, 0.134)","(DECR1, 0.131)","(CPT2, 0.128)","(CRAT, 0.127)","(HADHB, 0.076)","(ACADM, 0.05)","(ECHS1, 0.035)","(ACADSB, 0.009)","(ACAT1, -0.041)","(NBS1, -0.062)","(ACAA2, -0.076)","(CPT1A, -0.123)","(ACADL, -0.131)","(AMACR, -0.136)","(ACADS, -0.139)","(HADH2, -0.154)","(BC002942, -0.163)"]
[877,"radiation sensitivity BioCarta",27,0.651,1,0.88993,"(RB1, 0.289)","(CCNE1, 0.239)","(ATR, 0.183)","(ERBB2, 0.155)","(CCNB2, 0.13)","(CASP1, 0.116)","(BAX, 0.115)","(TNFSF6, 0.105)","(GAPD, 0.099)","(TP53, 0.061)","(IGFBP3, 0.046)","(LCMT2, 0.042)","(RAD50, 0.04)","(TNFRSF6, 0.027)","(BCL2, 0.02)","(EGFR, 0.019)","(CCND2, 0.01)","(IGF1R, 0)","(ACTB, -0.006)","(ATM, -0.011)","(CDKN1A, -0.022)","(GADD45A, -0.035)","(MDM2, -0.041)","(CCND3, -0.047)","(CDC2, -0.06)","(HRAS, -0.07)","(RAD51, -0.197)"]
[877,"lysosome organization and biogenesis (GO:0007040)",2,0.651,1,0.93061,"(HPS4, 0.426)","(NAGPA, -0.363)"]
[877,"purine base biosynthesis (GO:0009113)",2,0.651,1,0.93155,"(PAICS, 0.012)","(GMPS, -0.156)"]
[877,"p38mapkPathway BioCarta",39,0.651,1,0.93263,"(TRADD, 0.61)","(PLA2G4A, 0.478)","(ATF2, 0.327)","(CREB1, 0.253)","(RAC1, 0.251)","(RPS6KA5, 0.212)","(TRAF2, 0.189)","(MAP3K9, 0.162)","(MAPK14, 0.133)","(MYC, 0.098)","(TGFBR1, 0.036)","(HSPB1, 0.02)","(DAXX, 0.017)","(MAP3K5, 0.006)","(STAT1, 0.001)","(MAP2K6, 0)","(MEF2D, 0)","(MAPKAPK5, 0)","(MEF2B, 0)","(MAP3K1, 0)","(GRB2, 0)","(TGFB3, 0)","(DDIT3, 0)","(MEF2A, 0)","(MKNK1, -0.007)","(MAPKAPK2, -0.008)","(HRAS, -0.013)","(RIPK1, -0.015)","(MAP2K4, -0.018)","(TGFB1, -0.021)","(MEF2C, -0.022)","(TGFB2, -0.023)","(MAX, -0.038)","(MAP3K7, -0.06)","(HMGN1, -0.064)","(SHC1, -0.092)","(CDC42, -0.092)","(ELK1, -0.11)","(HSPB2, -0.123)"]
[882,"chaperone-mediated protein complex assembly (GO:0051131)",2,0.652,1,0.93422,"(CCT6B, 0.077)","(APCS, -0.062)"]
[882,"tachykinin signaling pathway (GO:0007217)",4,0.652,1,0.95066,"(TACR3, 0.17)","(TAC3, 0.002)","(TACR2, 0.001)","(TACR1, -0.092)"]
[882,"positive regulation of fatty acid oxidation (GO:0046321)",2,0.652,1,0.99995,"(PPARGC1A, 0.353)","(PRKAA1, -0.353)"]
[885,"pathogenesis (GO:0009405)",5,0.653,1,0.87794,"(TNIP1, 0.526)","(CLDN4, 0.198)","(HD, 0.109)","(PRF1, -0.15)","(HLA-DRB4, -0.233)"]
[885,"g1Pathway BioCarta",26,0.653,1,0.90352,"(RB1, 0.307)","(CCNE1, 0.289)","(ATR, 0.238)","(CDKN1B, 0.206)","(DHFR, 0.186)","(E2F1, 0.161)","(GSK3B, 0.136)","(CCNA1, 0.117)","(CDK6, 0.079)","(HDAC1, 0.02)","(CCND1, -0.005)","(TP53, -0.006)","(CDC25A, -0.013)","(CDC2, -0.016)","(ABL1, -0.03)","(TFDP1, -0.033)","(ATM, -0.055)","(SKP2, -0.059)","(TGFB3, -0.075)","(CDK2, -0.084)","(TGFB1, -0.094)","(CDKN1A, -0.097)","(CDKN2B, -0.109)","(TGFB2, -0.12)","(CDKN2A, -0.132)","(CDK4, -0.15)"]
[887,"mRNA catabolism (GO:0006402)",3,0.654,1,0.88153,"(HSPA1B, 0.522)","(ZFP36, -0.207)","(AUH, -0.253)"]
[887,"eea1Pathway The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system.",7,0.654,1,1,"(EGF, 0.416)","(TFRC, 0.335)","(RAB5A, 0.05)","(EGFR, 0.007)","(HGS, -0.047)","(TF, -0.15)","(EEA1, -0.202)"]
[887,"neuron lineage restriction (GO:0042055)",2,0.654,1,1,"(ZIC1, 0.391)","(ARNT2, -0.372)"]
[887,"CR CAM PNAS 2002",94,0.654,1,1,"(TIMP1, 0.798)","(CDH12, 0.371)","(ITGB5, 0.251)","(SERPINB5, 0.224)","(TNS, 0.217)","(ITGAV, 0.209)","(SELP, 0.187)","(SERPINI2, 0.181)","(TIMP3, 0.173)","(RAC1, 0.156)","(SELE, 0.148)","(CDH3, 0.135)","(DSC3, 0.127)","(ARHGAP6, 0.117)","(NEO1, 0.113)","(PKD1, 0.11)","(FN1, 0.1)","(MMP11, 0.082)","(CDH4, 0.073)","(BPAG1, 0.053)","(ITGA7, 0.037)","(ITGAX, 0.036)","(ITGB2, 0.03)","(TNC, 0.017)","(CDH6, 0.015)","(MMP1, 0.01)","(ITGAL, 0.009)","(DSG1, 0)","(ITGAE, 0)","(ALCAM, 0)","(ICAM2, 0)","(ICAM3, 0)","(MMP9, 0)","(ITGB1, 0)","(BYSL, 0)","(GPA33, 0)","(ITGA4, 0)","(CDH13, 0)","(NCAM1, 0)","(ITGB8, 0)","(ITGA5, 0)","(CD99, 0)","(PCDH1, 0)","(FAT, 0)","(PTK2, 0)","(SDC1, 0)","(JUP, 0)","(CDH15, 0)","(SELPLG, 0)","(ITGA3, 0)","(TIMP2, 0)","(ROCK1, 0)","(NCAM2, 0)","(ARHGAP1, 0)","(MCAM, 0)","(CDH7, 0)","(ITGA1, 0)","(PTPRU, 0)","(CDH17, 0)","(ITGB7, 0)","(WASL, 0)","(ITGB3, 0)","(ITGA2, 0)","(CDH18, 0)","(CD44, 0)","(MMP13, 0)","(CDH5, 0)","(F2R, 0)","(CD58, 0)","(CDH11, 0)","(ITGB4, 0)","(CXCR3, 0)","(VCAM1, 0)","(PKP1, 0)","(ADD3, 0)","(ITGAM, 0)","(CXCL12, 0)","(CD47, 0)","(SELL, 0)","(ANK1, 0)","(CEACAM1, 0)","(IL8, 0)","(ZYX, 0)","(PECAM1, 0)","(GJA4, 0)","(CNTN1, 0)","(CDH1, 0)","(SEMA4D, 0)","(CD97, 0)","(ICAM1, 0)","(DCC, 0)","(ITGA9, 0)","(HMMR, -0.086)","(CDH2, -0.115)"]
[891,"regulation of mitotic recombination (GO:0000019)",2,0.655,1,0.94653,"(RAD50, 0.186)","(MRE11A, -0.24)"]
[891,"insulinPathway BioCarta",21,0.655,1,1,"(SLC2A4, 0.702)","(JUN, 0.388)","(SRF, 0.244)","(FOS, 0.214)","(RAF1, 0.058)","(PTPN11, 0.047)","(SOS1, 0.03)","(INS, -0.022)","(IRS1, -0.026)","(GRB2, -0.031)","(PIK3R1, -0.033)","(MAPK3, -0.037)","(INSR, -0.038)","(MAP2K1, -0.044)","(HRAS, -0.06)","(MAPK8, -0.065)","(SHC1, -0.079)","(ELK1, -0.087)","(PIK3CA, -0.099)","(RASA1, -0.159)","(CSNK2A1, -0.171)"]
[893,"p35alzheimersPathway BioCarta",10,0.656,1,0.68849,"(PPP2CA, 0.484)","(CAPNS1, 0.306)","(GSK3B, 0.23)","(APP, 0.22)","(CSNK1A1, 0.086)","(CAPN1, 0.006)","(MAPT, -0.036)","(CDK5, -0.099)","(CSNK1D, -0.131)","(CDK5R1, -0.229)"]
[893,"mesodermal cell fate determination (GO:0007500)",3,0.656,1,0.93456,"(SHH, 0.18)","(KLF4, 0.14)","(TRIM15, -0.291)"]
[893,"negative regulation of T cell proliferation (GO:0042130)",2,0.656,1,0.94222,"(SFTPD, 0.25)","(GLMN, -0.305)"]
[896,"il5Pathway BioCarta",10,0.657,1,0.98438,"(CD4, 0.468)","(HLA-DRB1, 0.408)","(IL6, 0.24)","(IL1B, 0.149)","(IL5, 0.086)","(HLA-DRA, 0.073)","(IL5RA, -0.141)","(CCL11, -0.151)","(IL4, -0.164)","(CCR3, -0.186)"]
[896,"regulation of signal transduction (GO:0009966)",2,0.657,1,1,"(TDGF1, 0.157)","(YWHAH, -0.021)"]
[898,"RNA processing (GO:0006396)",19,0.658,1,0.70837,"(RBMS2, 0.488)","(DDX17, 0.431)","(RBMS1, 0.325)","(HNRPD, 0.217)","(HNRPH1, 0.164)","(BICD1, 0.097)","(RENT1, 0.092)","(RBM5, 0.041)","(HNRPU, 0.039)","(RBM6, -0.015)","(DDX41, -0.032)","(HNRPF, -0.036)","(DUSP11, -0.062)","(PABPC4, -0.071)","(RBMY1A1, -0.086)","(RBPMS, -0.108)","(DDX54, -0.117)","(RBM3, -0.137)","(HNRPA2B1, -0.158)"]
[898,"mcalpainPathway BioCarta",24,0.658,1,0.89299,"(MYLK, 0.296)","(PRKACB, 0.211)","(EGF, 0.21)","(ACTA1, 0.208)","(CAPNS1, 0.193)","(PRKAR2A, 0.16)","(CAPN2, 0.128)","(PRKAR2B, 0.118)","(MAPK3, 0.1)","(VIL2, 0.045)","(PRKAR1B, 0.044)","(ITGB1, 0.039)","(MAPK1, -0.004)","(EGFR, -0.01)","(PXN, -0.016)","(CAPN1, -0.019)","(MYL2, -0.038)","(HRAS, -0.048)","(CXCR3, -0.059)","(PRKACG, -0.061)","(TLN1, -0.068)","(PTK2, -0.116)","(PRKAR1A, -0.119)","(ITGA1, -0.165)"]
[898,"activation of JNK activity (GO:0007257)",7,0.658,1,0.9892,"(MAP3K9, 0.324)","(MAP3K2, 0.208)","(MAP4K5, 0.08)","(MAP3K5, -0.009)","(MAP4K1, -0.045)","(DAXX, -0.046)","(MAP3K10, -0.135)"]
[901,"tyrosine phosphorylation of STAT protein (GO:0007260)",3,0.66,1,0.91893,"(F2, 0.082)","(F2R, 0.058)","(STAT1, 0.043)"]
[902,"induction of apoptosis by hormones (GO:0008628)",3,0.661,1,0.99594,"(SSTR3, 0.544)","(TP53, -0.034)","(PTH, -0.358)"]
[902,"positive regulation of cell migration (GO:0030335)",4,0.661,1,1,"(SPHK1, 0.154)","(EGFR, 0.075)","(ANGPTL3, -0.001)","(TDGF1, -0.02)"]
[902,"ST STAT3 Pathway Signalling Transduction KE",11,0.661,1,1,"(IL6R, 0.519)","(IL6, 0.19)","(PTPRU, 0.179)","(JAK1, 0.096)","(SRC, 0.039)","(JAK3, 0.023)","(PIAS3, -0.077)","(CISH, -0.083)","(REG1A, -0.11)","(JAK2, -0.187)","(STAT3, -0.261)"]
[905,"filopodium formation (GO:0046847)",3,0.662,1,0.94397,"(FGD6, 0.125)","(FGD2, 0.052)","(FGD1, 0.017)"]
[906,"chemotaxis (GO:0006935)",72,0.663,1,0.54,"(KAL1, 0.555)","(IL1A, 0.295)","(CCL17, 0.229)","(CXCL14, 0.227)","(CCL20, 0.218)","(MAPK14, 0.193)","(CCRL1, 0.175)","(IL8RA, 0.173)","(RNASE2, 0.173)","(CCL22, 0.17)","(PIK3CB, 0.164)","(CXCL12, 0.159)","(DEFB4, 0.152)","(CX3CR1, 0.114)","(XCR1, 0.109)","(CCL3, 0.106)","(CCL23, 0.105)","(CCL21, 0.102)","(C5, 0.1)","(CCL16, 0.091)","(CCR6, 0.045)","(CMKLR1, 0.028)","(CCR2, 0.026)","(FPR1, 0.014)","(RALBP1, 0.013)","(PLD1, 0.008)","(CCL25, 0.006)","(CCR9, 0.004)","(CXCL13, 0)","(IL4, 0)","(FPRL1, 0)","(MAPK1, 0)","(PLAUR, 0)","(CXCL11, 0)","(MAP2K1, 0)","(CXCR3, 0)","(FGF2, 0)","(CCL2, 0)","(CCL8, 0)","(SCYE1, 0)","(CCL24, 0)","(PLAU, 0)","(PTAFR, 0)","(HRAS, 0)","(CXCL5, 0)","(CCL13, 0)","(CCR8, 0)","(CCR3, 0)","(RALA, 0)","(XCL1, 0)","(CCL15, 0)","(CCR7, 0)","(CCL18, 0)","(CCL5, 0)","(CCR4, 0)","(C5R1, 0)","(CCL1, 0)","(LTB4R2, 0)","(CCL27, 0)","(FOSL1, 0)","(CCBP2, 0)","(CCL7, 0)","(CXCL9, -0.002)","(LECT2, -0.014)","(IL8RB, -0.02)","(CXCL2, -0.022)","(CCL19, -0.065)","(CXCL10, -0.067)","(CXCL6, -0.068)","(SPN, -0.114)","(IL8, -0.117)","(CCL11, -0.2)"]
[906,"MAP00910 Nitrogen metabolism GenMAPP",21,0.663,1,0.99822,"(AMT, 1.105)","(CA9, 0.355)","(CA8, 0.305)","(ANKRD1, 0.075)","(GLUL, 0.057)","(CA5A, 0.056)","(CA7, 0.027)","(CA12, 0.022)","(CA1, -0.008)","(CA5B, -0.033)","(CA6, -0.041)","(GLUD1, -0.067)","(CPS1, -0.074)","(HAL, -0.077)","(ASNS, -0.096)","(DDX3X, -0.114)","(CA14, -0.151)","(CA4, -0.151)","(CTH, -0.187)","(CA2, -0.19)","(CA3, -0.215)"]
[908,"DNA repair (GO:0006281)",44,0.664,1,0.82317,"(RAD51C, 0.736)","(XRCC3, 0.617)","(ATR, 0.227)","(ERCC6, 0.203)","(FANCA, 0.171)","(ATRX, 0.159)","(GADD45G, 0.144)","(RPA3, 0.126)","(HMGB2, 0.111)","(CSNK1E, 0.109)","(TREX2, 0.1)","(CCNH, 0.1)","(GTF2H4, 0.064)","(IGHMBP2, 0.062)","(LIG1, 0.06)","(UVRAG, 0.043)","(MNAT1, 0.038)","(GTF2H1, 0.032)","(RECQL, 0.025)","(POLE2, 0.023)","(RUVBL2, 0.02)","(RPA1, 0.008)","(POLB, 0.006)","(RECQL5, 0)","(CSNK1D, 0)","(LIG3, 0)","(RAD51L1, 0)","(FANCC, 0)","(BLM, 0)","(RAD54L, 0)","(RECQL4, -0.004)","(POLQ, -0.005)","(XRCC2, -0.015)","(RAD51, -0.036)","(GADD45A, -0.045)","(MBD4, -0.05)","(FANCG, -0.07)","(PNKP, -0.082)","(SMC1L1, -0.087)","(POLD1, -0.094)","(POLI, -0.097)","(BTG2, -0.105)","(HMGB1, -0.122)","(ATM, -0.127)"]
[908,"ranklPathway BioCarta",14,0.664,1,1,"(NFKB1, 0.988)","(FOSL2, 0.252)","(FOS, 0.19)","(IFNB1, 0.021)","(MAPK8, -0.008)","(TRAF6, -0.046)","(ISGF3G, -0.05)","(IFNAR1, -0.062)","(PRKR, -0.085)","(TNFSF11, -0.107)","(TNFRSF11A, -0.115)","(IFNAR2, -0.122)","(RELA, -0.161)","(FOSL1, -0.179)"]
[910,"regulation of neurotransmitter levels (GO:0001505)",2,0.665,1,0.89878,"(GLUL, 0.084)","(GABRA2, -0.093)"]
[910,"cacamPathway Calcium functions as a second messenger activating the calcium/calmodulin-dependent kinases, which phosphorylate targets such as CREB.",12,0.665,1,1,"(CREB1, 0.559)","(CAMK1G, 0.353)","(CAMK2A, 0.152)","(CAMK4, 0.032)","(CAMK2B, 0.02)","(CALM2, 0.019)","(CALM1, 0)","(CAMKK2, -0.016)","(CAMK1, -0.042)","(CAMK2G, -0.076)","(CALM3, -0.107)","(SYT1, -0.19)"]
[912,"protein amino acid glycosylation (GO:0006486)",21,0.666,1,0.80395,"(B3GALT2, 0.489)","(FUT4, 0.275)","(IL17, 0.203)","(ALG5, 0.176)","(TSTA3, 0.164)","(FUT6, 0.142)","(B3GALT5, 0.133)","(COG2, 0.124)","(DPM1, 0.071)","(DPM2, 0.055)","(FUT2, -0.013)","(FUT1, -0.047)","(B3GAT1, -0.052)","(B3GALT4, -0.078)","(SDF2, -0.098)","(FUT9, -0.098)","(FUT5, -0.11)","(B3GALT3, -0.134)","(FUT7, -0.145)","(LARGE, -0.153)","(LRP2, -0.159)"]
[912,"ST Wnt beta catenin Pathway Signalling Transduction KE",30,0.666,1,1,"(AKT2, 0.572)","(DKK1, 0.466)","(C22orf2, 0.384)","(LRP1, 0.282)","(PTPRA, 0.235)","(FRAT1, 0.177)","(AXIN1, 0.124)","(GSK3B, 0.121)","(GSK3A, 0.085)","(MVP, 0.083)","(WIF1, 0.082)","(LAMR1, 0.076)","(PSEN1, 0.047)","(CSNK1A1, 0.026)","(DKK3, 0)","(DVL1, 0)","(TSHB, -0.011)","(CER1, -0.025)","(SENP2, -0.029)","(AKT3, -0.055)","(ANKRD6, -0.059)","(FSTL1, -0.061)","(DKK2, -0.071)","(APC, -0.088)","(DKK4, -0.099)","(SFRP1, -0.11)","(DACT1, -0.119)","(PIN1, -0.126)","(AKT1, -0.134)","(CTNNB1, -0.142)"]
[914,"negative regulation of protein catabolism (GO:0042177)",2,0.667,1,0.95162,"(MDM4, 0.199)","(INS, -0.219)"]
[915,"amino acid metabolism (GO:0006520)",24,0.668,1,0.97773,"(SLC7A1, 0.379)","(CTNS, 0.322)","(PTS, 0.278)","(SLC7A7, 0.253)","(SLC6A6, 0.185)","(MAT1A, 0.18)","(GGT1, 0.074)","(SLC6A14, 0.064)","(GGTLA1, 0.018)","(GLS2, 0.015)","(SLC7A8, 0.008)","(OAT, 0.005)","(HMGCL, -0.001)","(SLC7A2, -0.001)","(SLC7A5, -0.031)","(SLC25A15, -0.046)","(MTHFR, -0.047)","(GSS, -0.061)","(NOS3, -0.097)","(SLC7A4, -0.105)","(PEPD, -0.117)","(SLC3A1, -0.133)","(QDPR, -0.18)","(SLC7A9, -0.194)"]
[916,"cleavage of lamin (GO:0006922)",2,0.669,1,0.99202,"(GZMB, -0.01)","(GZMA, -0.043)"]
[917,"UDP-N-acetylgalactosamine metabolism (GO:0019276)",2,0.67,1,0.95284,"(ChGn, 0.149)","(EXTL2, 0.104)"]
[917,"achPathway Nicotinic acetylcholine receptors are ligand-gated ion channels that primarily mediate neuromuscular signaling and may inhibit neuronal apoptosis via the AKT pathway.",15,0.67,1,0.98361,"(PTK2B, 0.637)","(TERT, 0.207)","(FOXO3A, 0.183)","(BAD, 0.091)","(TNFSF6, 0.054)","(YWHAH, 0.017)","(SRC, 0.007)","(RAPSN, -0.007)","(PIK3R1, -0.056)","(PTK2, -0.058)","(CHRNG, -0.077)","(CHRNB1, -0.124)","(PIK3CA, -0.131)","(MUSK, -0.142)","(AKT1, -0.199)"]
[919,"DNA unwinding during replication (GO:0006268)",2,0.671,1,0.86866,"(HMGB2, 0.391)","(RAD51, -0.531)"]
[920,"acetyl-CoA metabolism (GO:0006084)",2,0.672,1,0.94102,"(MLYCD, 0.118)","(PDHA1, -0.228)"]
[920,"erbb4Pathway ErbB4 (aka HER4) is a receptor tyrosine kinase that binds neuregulins as well as members of the EGF family, which also target EGF receptors.",6,0.672,1,1,"(ADAM17, 0.59)","(PSEN1, 0.14)","(NRG2, -0.037)","(ERBB4, -0.049)","(PRKCB1, -0.151)","(PRKCA, -0.189)"]
[920,"MAP00600 Sphingoglycolipid metabolism GenMAPP",13,0.672,1,1,"(ARSE, 0.686)","(GBA, 0.185)","(GALGT, 0.112)","(UGCG, 0.103)","(HEXA, 0.098)","(ARSA, 0.027)","(ARSD, -0.009)","(HEXB, -0.075)","(GLA, -0.081)","(B3GALT4, -0.082)","(GLB1, -0.086)","(NEU1, -0.12)","(ASAH1, -0.124)"]
[923,"branched chain family amino acid biosynthesis (GO:0009082)",2,0.673,1,0.98655,"(BCAT2, 0.028)","(BCAT1, -0.07)"]
[923,"regulation of apoptosis (GO:0042981)",6,0.673,1,1,"(PRDX2, 0.399)","(BTG1, 0.214)","(BRCA1, 0.14)","(PEA15, 0.053)","(CD3G, -0.04)","(APAF1, -0.129)"]
[923,"heterophilic cell adhesion (GO:0007157)",2,0.673,1,1,"(LGALS7, 0.001)","(REG3A, 0)"]
[926,"cytoskeleton organization and biogenesis (GO:0007010)",19,0.674,1,0.92312,"(ARHGAP4, 0.811)","(PYY, 0.3)","(CCL3, 0.191)","(PRKCI, 0.186)","(FGD2, 0.08)","(PLD2, 0.06)","(YWHAH, 0.05)","(FGD6, 0.043)","(ARHGAP1, -0.022)","(FGD1, -0.05)","(TMOD1, -0.051)","(PCLO, -0.054)","(APOE, -0.06)","(MARK1, -0.092)","(EPB49, -0.097)","(KISS1, -0.111)","(DES, -0.112)","(ABI2, -0.148)","(CNN2, -0.162)"]
[927,"generation of action potential (GO:0019228)",3,0.675,1,1,"(KCNMB2, 0.347)","(KCNMB4, -0.241)","(KCNMB3, -0.259)"]
[928,"cellular defense response (GO:0006968)",54,0.677,1,0.52288,"(CSF3, 0.391)","(ADORA2A, 0.288)","(TYROBP, 0.287)","(PTMS, 0.279)","(GNLY, 0.267)","(NCF1, 0.246)","(ADORA2B, 0.229)","(LBP, 0.201)","(CCR6, 0.191)","(NCR1, 0.185)","(HLA-G, 0.165)","(UMOD, 0.13)","(CX3CR1, 0.115)","(CSF2, 0.084)","(NCR3, 0.078)","(KIR3DL2, 0.075)","(NCF2, 0.065)","(ZNF148, 0.063)","(LY6H, 0.036)","(CCR9, 0.026)","(LGALS3BP, 0.009)","(TCIRG1, 0)","(MAPRE2, 0)","(NCR2, 0)","(SPN, 0)","(ZNF161, 0)","(CD160, 0)","(CCR2, 0)","(CD19, 0)","(ITGB1, -0.006)","(CCL5, -0.008)","(MNDA, -0.014)","(BECN1, -0.015)","(KLRC3, -0.02)","(LILRB2, -0.024)","(CD5L, -0.025)","(CD244, -0.026)","(IL1RL2, -0.026)","(LSP1, -0.028)","(IL4, -0.034)","(CCL11, -0.036)","(CD7, -0.042)","(GAGE1, -0.044)","(C3AR1, -0.058)","(FOSL1, -0.059)","(C5R1, -0.084)","(KIR2DL4, -0.088)","(CXCL9, -0.09)","(IL8RB, -0.092)","(ITK, -0.111)","(LY96, -0.113)","(CCR3, -0.125)","(KLRC4, -0.137)","(PRF1, -0.145)"]
[928,"blymphocytePathway B cells express the major histocompatibility complex (class II MHC), immunoglobulins, adhesion proteins, and other factors on their cell surface.",11,0.677,1,1,"(HLA-DRB1, 0.367)","(ITGB2, 0.243)","(ITGAL, 0.142)","(TNFRSF5, 0.138)","(HLA-DRA, 0.042)","(FCGR2B, 0.009)","(CR1, -0.009)","(PTPRC, -0.016)","(CD80, -0.038)","(CR2, -0.091)","(ICAM1, -0.17)"]
[930,"lipid raft polarization (GO:0001766)",2,0.678,1,0.9142,"(CD2, 0.08)","(MAL, -0.149)"]
[930,"SA REG CASCADE OF CYCLIN EXPR SigmaAldrich",13,0.678,1,1,"(CCNE1, 0.402)","(CDKN1B, 0.331)","(E2F1, 0.276)","(CCNA1, 0.059)","(CCNE2, 0.056)","(E2F2, 0.047)","(CCNA2, -0.019)","(CCND1, -0.025)","(E2F4, -0.04)","(CDK2, -0.043)","(PRB1, -0.103)","(CDKN2A, -0.154)","(CDK4, -0.188)"]
[932,"fasPathway Binding of the Fas ligand to the Fas receptor induces caspase activation and consequent apoptosis in the Fas-expressing cell.",30,0.679,1,0.73884,"(DFFB, 0.438)","(CASP3, 0.37)","(JUN, 0.342)","(FAF1, 0.279)","(RB1, 0.229)","(PTPN13, 0.106)","(CASP10, 0.101)","(ADPRT, 0.099)","(TNFSF6, 0.086)","(LMNA, 0.068)","(PAK2, 0.067)","(CASP6, 0.065)","(CASP8, 0.06)","(LMNB2, 0.049)","(MAPK8, 0.026)","(CFLAR, -0.01)","(TNFRSF6, -0.023)","(PRKDC, -0.03)","(SPTAN1, -0.034)","(CASP7, -0.042)","(DAXX, -0.045)","(PAK1, -0.051)","(LMNB1, -0.054)","(MAP2K4, -0.07)","(DFFA, -0.076)","(MAP3K7, -0.08)","(FADD, -0.094)","(RIPK2, -0.107)","(ARHGDIB, -0.112)","(MAP3K1, -0.116)"]
[932,"response to bacteria (GO:0009617)",2,0.679,1,0.96839,"(SLC11A1, 0.329)","(CHIT1, -0.446)"]
[934,"epoPathway Erythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia.",19,0.68,1,0.88045,"(PLCG1, 0.615)","(JUN, 0.419)","(EPOR, 0.264)","(FOS, 0.154)","(EPO, 0.089)","(RAF1, 0.085)","(MAPK3, 0.044)","(SOS1, 0.035)","(STAT5A, 0.013)","(STAT5B, 0)","(MAPK8, -0.009)","(SHC1, -0.032)","(ELK1, -0.07)","(HRAS, -0.077)","(PTPN6, -0.083)","(MAP2K1, -0.096)","(CSNK2A1, -0.1)","(GRB2, -0.104)","(JAK2, -0.157)"]
[934,"establishment of tissue polarity (GO:0007164)",3,0.68,1,0.92998,"(FZD5, 0.252)","(FZD2, 0.023)","(FZD6, -0.115)"]
[936,"cptPathway BLACK",3,0.681,1,1,"(CPT2, 0.303)","(SLC25A20, -0.075)","(CPT1A, -0.357)"]
[937,"G13 Signaling Pathway BioCarta",29,0.682,1,0.57369,"(CFL1, 0.641)","(DIAPH1, 0.376)","(RAC1, 0.245)","(PIK3CB, 0.233)","(PIP5K2A, 0.153)","(WAS, 0.136)","(PPP1CB, 0.131)","(PFN1, 0.115)","(CIT, 0.084)","(ARHGEF1, 0.082)","(ARHGDIG, 0.046)","(IQGAP1, 0.017)","(CALM1, -0.003)","(PAK3, -0.018)","(CALM2, -0.026)","(GNA13, -0.036)","(WASL, -0.04)","(MYBPH, -0.048)","(PIK3R2, -0.055)","(PRKCL1, -0.069)","(CDC42, -0.085)","(MAP3K4, -0.086)","(ARHGDIB, -0.123)","(PIK3CA, -0.131)","(LIMK1, -0.141)","(MAPK10, -0.149)","(CALM3, -0.165)","(IQGAP2, -0.17)","(PIK3CD, -0.18)"]
[937,"transcription from RNA polymerase III promoter (GO:0006383)",11,0.682,1,0.62054,"(GTF3C1, 0.837)","(POLR2K, 0.105)","(GTF3A, 0.074)","(GTF3C2, 0.054)","(SNAPC2, 0.007)","(SNAPC1, 0.005)","(SSB, -0.05)","(GTF3C5, -0.072)","(POLR3K, -0.081)","(SNAPC3, -0.134)","(GTF3C3, -0.193)"]
[937,"protein amino acid geranylgeranylation (GO:0018348)",3,0.682,1,0.77991,"(CHM, 0.09)","(PGGT1B, 0.022)","(FNTA, 0.001)"]
[937,"glucocorticoid biosynthesis (GO:0006704)",2,0.682,1,0.92227,"(HSD11B2, 0.25)","(CYP11B2, -0.08)"]
[937,"myoblast differentiation (GO:0045445)",2,0.682,1,0.95162,"(MBNL1, 0.238)","(MAPK12, -0.248)"]
[937,"feederPathway Sugars such as mannose, galactose, and fructose are enzymatically converted to glucose via \"feeder\" pathways that lead to glycolysis.",9,0.682,1,0.95442,"(MPI, 0.472)","(PYGL, 0.106)","(TPI1, 0.054)","(PYGM, 0.051)","(HK1, 0.042)","(KHK, 0.04)","(LCT, -0.108)","(TREH, -0.173)","(PGM1, -0.269)"]
[943,"anthraxPathway BLACK",2,0.683,1,0.7723,"(MAP2K2, 0.05)","(MAP2K1, -0.192)"]
[943,"response to unfolded protein (GO:0006986)",19,0.683,1,0.97849,"(DNAJB4, 0.388)","(HSPB7, 0.286)","(HSPCB, 0.28)","(HSPA1B, 0.225)","(SERPINH1, 0.157)","(HERPUD1, 0.154)","(TXNDC4, 0.14)","(HSPA6, 0.106)","(DNAJC4, 0.094)","(DNAJA1, 0.023)","(DNAJB2, -0.011)","(HSPB1, -0.036)","(HSPB3, -0.052)","(DNAJB5, -0.081)","(TRA1, -0.089)","(HSPA1L, -0.116)","(DNAJB1, -0.127)","(HSPH1, -0.135)","(TOR1B, -0.169)"]
[945,"tRNA modification (GO:0006400)",2,0.684,1,0.88243,"(METTL1, 0.35)","(SSB, -0.299)"]
[945,"PYR Manually Curated",8,0.684,1,0.97874,"(PDHB, 0.685)","(PDK4, 0.283)","(PDK1, -0.017)","(PDHA2, -0.032)","(PDK3, -0.051)","(PDHA1, -0.059)","(PPM2C, -0.083)","(PDHX, -0.174)"]
[947,"ST ERK1 ERK2 MAPK Pathway Signalling Transduction KE",31,0.685,1,1,"(NFKB1, 0.738)","(CREB1, 0.294)","(CREB3, 0.277)","(RPS6KA2, 0.173)","(BAD, 0.139)","(TRAF3, 0.107)","(ARAF1, 0.105)","(SOS2, 0.103)","(MAPK3, 0.102)","(MAP2K2, 0.061)","(SOS1, 0.054)","(BRAF, 0.009)","(HTATIP, 0.008)","(MKNK2, 0.008)","(RPS6KA1, 0.008)","(GRB2, 0.005)","(MAPK1, -0.001)","(DUSP4, -0.001)","(MAP2K1, -0.007)","(EIF4E, -0.019)","(ATF1, -0.03)","(DUSP6, -0.037)","(SHC1, -0.038)","(MKNK1, -0.039)","(MAP3K8, -0.039)","(DUSP9, -0.046)","(MOS, -0.076)","(RPS6KA3, -0.091)","(CREB5, -0.096)","(COPEB, -0.109)","(RAP1A, -0.191)"]
[948,"negative regulation of S phase of mitotic cell cycle (GO:0045749)",3,0.686,1,0.9274,"(APBB2, 0.225)","(APBB1, -0.011)","(PCOLN3, -0.111)"]
[949,"negative regulation of transcription from RNA polymerase II promoter (GO:0000122)",51,0.687,1,0.78133,"(TGIF, 0.628)","(ZFP161, 0.351)","(ZNF202, 0.288)","(HSBP1, 0.229)","(SPI1, 0.201)","(BCL6, 0.197)","(RB1, 0.197)","(DNMT1, 0.194)","(IRF2, 0.189)","(PPARD, 0.182)","(E2F1, 0.167)","(MXD4, 0.15)","(KLF3, 0.15)","(ZNF593, 0.147)","(ZNF174, 0.123)","(FOXD3, 0.083)","(ZNF148, 0.073)","(NSD1, 0.04)","(ZNF281, 0.037)","(ZMYND11, 0.007)","(FOXE1, 0)","(CSDA, 0)","(CTCF, 0)","(NKX2-5, 0)","(ZNF157, 0)","(VHL, 0)","(FOSB, 0)","(MEIS2, 0)","(E2F6, 0)","(MDM4, 0)","(DR1, -0.005)","(CUTL1, -0.013)","(PRDM1, -0.02)","(ZNF238, -0.029)","(IRF7, -0.031)","(STAT3, -0.033)","(ZNF189, -0.034)","(MDM2, -0.035)","(NFX1, -0.036)","(SNAI2, -0.036)","(MEN1, -0.045)","(NR0B2, -0.046)","(ORC2L, -0.05)","(POU4F2, -0.069)","(TWIST1, -0.07)","(MECP2, -0.074)","(DRAP1, -0.089)","(ZNF345, -0.092)","(ZNF136, -0.13)","(ZNF177, -0.143)","(TCF8, -0.148)"]
[949,"cell-cell adhesion (GO:0016337)",5,0.687,1,0.98905,"(CRISP3, 0.224)","(EGFR, 0.09)","(C1QR1, 0.073)","(CD2, -0.014)","(ANXA9, -0.172)"]
[949,"regulation of pH (GO:0006885)",2,0.687,1,0.99079,"(SLC9A7, 0.267)","(SLC9A1, -0.265)"]
[952,"ST p38 MAPK Pathway Signalling Transduction KE",36,0.688,1,1,"(NFKB1, 0.706)","(MAPK13, 0.411)","(CREB1, 0.302)","(MAPK11, 0.286)","(CREB3, 0.269)","(MAPK14, 0.201)","(SRF, 0.188)","(NR2C2, 0.123)","(MAP3K7IP1, 0.072)","(DUSP1, 0.033)","(MAP3K5, 0.029)","(GADD45A, 0.008)","(MAP3K7, 0)","(EIF4E, 0)","(MAPKAPK2, 0)","(IL1R1, 0)","(MKNK2, -0.005)","(MAPK1, -0.009)","(CDC42, -0.012)","(MKNK1, -0.023)","(MAPKAPK5, -0.028)","(MAP3K10, -0.032)","(HSPB1, -0.041)","(MAP2K3, -0.042)","(MAP2K4, -0.049)","(CREB5, -0.059)","(ATF1, -0.06)","(MAP3K4, -0.066)","(AKT1, -0.091)","(MAP3K7IP2, -0.108)","(TRAF6, -0.109)","(DUSP10, -0.112)","(ELK1, -0.114)","(MAP2K6, -0.114)","(MYEF2, -0.122)","(MAPK12, -0.14)"]
[952,"cell2cellPathway Epithelial cell adhesion proteins such as cadherins transduce signals into the cell via catenins, which alter cell shape and motility.",12,0.688,1,1,"(CSK, 0.568)","(VCL, 0.256)","(ACTN3, 0.157)","(CTNNA2, 0.13)","(SRC, 0.105)","(PXN, -0.025)","(CTNNB1, -0.029)","(ACTN1, -0.078)","(ACTN2, -0.094)","(PTK2, -0.111)","(CTNNA1, -0.176)","(PECAM1, -0.186)"]
[954,"central nervous system development (GO:0007417)",58,0.69,1,0.72022,"(GSTP1, 0.374)","(DCAMKL1, 0.335)","(ADORA2A, 0.239)","(PTS, 0.232)","(CNTN6, 0.194)","(ADAM22, 0.194)","(NEUROG3, 0.188)","(POU6F2, 0.188)","(PROP1, 0.176)","(SNCA, 0.165)","(PSPN, 0.157)","(JARID2, 0.153)","(SNTG2, 0.136)","(SH3GL3, 0.104)","(UGT8, 0.037)","(SOX3, 0.036)","(PAX6, 0.03)","(ACCN1, 0.028)","(DCX, 0.027)","(SH3GL2, 0.017)","(CELSR1, 0)","(S100B, 0)","(POU3F3, 0)","(BTD, 0)","(RPS6KA6, 0)","(ADARB1, 0)","(C7orf16, 0)","(GRIK1, 0)","(SLIT3, 0)","(NPAS2, 0)","(PARK2, 0)","(NHLH2, 0)","(NPTX1, 0)","(DRP2, 0)","(ATOH1, 0)","(NCKAP1, 0)","(SERPINI1, 0)","(ADAM23, 0)","(NHLH1, 0)","(RNF103, 0)","(MTR, 0)","(WNT1, 0)","(RPS6KA3, -0.006)","(LHX5, -0.009)","(HPCAL4, -0.012)","(NPAS1, -0.014)","(DSCR1, -0.023)","(IL1RAPL2, -0.024)","(MBP, -0.028)","(ALDH3A2, -0.03)","(PNMA1, -0.035)","(JRKL, -0.036)","(PTPRZ1, -0.076)","(ARNT2, -0.084)","(MOG, -0.095)","(MAL, -0.108)","(SHC3, -0.125)","(PCP4, -0.138)"]
[954,"protein kinase cascade (GO:0007243)",42,0.69,1,0.94654,"(MAPK13, 0.428)","(ADAM9, 0.408)","(ADRA1B, 0.277)","(MAPK11, 0.274)","(MAP4K4, 0.222)","(MAP4K3, 0.207)","(RPS6KA2, 0.182)","(RPS6KA5, 0.143)","(ICK, 0.136)","(ADRB2, 0.121)","(MAPK14, 0.12)","(STK38, 0.081)","(DAPK1, 0.078)","(FYN, 0.062)","(MAP4K5, 0.014)","(MAP4K2, 0.007)","(BLK, 0)","(TNIK, 0)","(ADRA1A, 0)","(C7orf16, 0)","(STK17A, 0)","(SGK2, 0)","(TEC, 0)","(MAP4K1, -0.012)","(MARK2, -0.021)","(DAPK2, -0.023)","(FYB, -0.026)","(MKNK2, -0.03)","(MAP3K12, -0.037)","(MARK1, -0.057)","(SRC, -0.073)","(NLK, -0.079)","(STK17B, -0.084)","(ITGB1BP1, -0.088)","(STK4, -0.09)","(STK38L, -0.104)","(MKNK1, -0.105)","(PINK1, -0.121)","(STK3, -0.123)","(DAPK3, -0.134)","(AKAP11, -0.15)","(RPS6KA4, -0.16)"]
[954,"leukocyte adhesion (GO:0007159)",4,0.69,1,0.97615,"(ITGB2, 0.442)","(ITGAE, 0.056)","(TNF, -0.188)","(SYK, -0.386)"]
[954,"HOXA9 DOWN Dorsam et al 2004",36,0.69,1,1,"(GATA2, 0.465)","(FCGRT, 0.446)","(JUN, 0.327)","(ARNTL, 0.322)","(SDCBP, 0.188)","(DSIPI, 0.149)","(USP1, 0.135)","(CDC37, 0.115)","(KRT18, 0.104)","(GLRX, 0.103)","(MYC, 0.058)","(LYZ, 0.038)","(SRP72, 0.031)","(SBNO1, 0.017)","(IGF2, 0)","(SERPINB9, 0)","(VHL, 0)","(DNCLI2, -0.007)","(S100A8, -0.008)","(FXR1, -0.009)","(TPR, -0.014)","(DCT, -0.02)","(RBBP6, -0.026)","(OSBPL8, -0.032)","(HBE1, -0.05)","(LYN, -0.056)","(BMI1, -0.058)","(FPRL1, -0.061)","(JUNB, -0.066)","(CISH, -0.076)","(SFRS11, -0.083)","(SDC4, -0.087)","(MAN2A2, -0.096)","(WSB1, -0.135)","(CD36, -0.135)","(CLCN7, -0.183)"]
[958,"induction of apoptosis via death domain receptors (GO:0008625)",7,0.692,1,0.68879,"(IL18, 0.663)","(DIABLO, 0.059)","(DAXX, -0.014)","(CRADD, -0.096)","(DEDD, -0.101)","(FADD, -0.211)","(BID, -0.251)"]
[958,"glucose catabolism (GO:0006007)",2,0.692,1,0.94422,"(GPD2, 0.246)","(TKTL1, -0.361)"]
[958,"il6Pathway BioCarta",21,0.692,1,0.9681,"(JUN, 0.383)","(IL6R, 0.364)","(SRF, 0.278)","(CEBPB, 0.187)","(FOS, 0.169)","(IL6, 0.157)","(PTPN11, 0.053)","(MAP2K1, 0.038)","(MAPK3, 0.032)","(SOS1, 0.021)","(JAK1, 0.014)","(RAF1, 0.013)","(JAK3, -0.023)","(GRB2, -0.03)","(SHC1, -0.064)","(HRAS, -0.09)","(CSNK2A1, -0.123)","(ELK1, -0.138)","(STAT3, -0.151)","(IL6ST, -0.17)","(JAK2, -0.178)"]
[958,"protein amino acid acetylation (GO:0006473)",3,0.692,1,0.97315,"(GCN5L2, 0.751)","(ING4, -0.28)","(PCAF, -0.363)"]
[958,"gsk3Pathway BioCarta",26,0.692,1,0.98378,"(NFKB1, 0.789)","(LBP, 0.321)","(IRAK1, 0.285)","(PPP2CA, 0.257)","(CD14, 0.238)","(TLR4, 0.206)","(GSK3B, 0.115)","(PDPK1, 0.104)","(AXIN1, 0.087)","(CCND1, 0.031)","(DVL1, 0.027)","(GJA1, 0.012)","(FZD1, -0.012)","(APC, -0.018)","(GNAI1, -0.031)","(LEF1, -0.038)","(PIK3R1, -0.057)","(AKT1, -0.059)","(CTNNB1, -0.069)","(PRKR, -0.07)","(PIK3CA, -0.074)","(TOLLIP, -0.085)","(LY96, -0.102)","(WNT1, -0.158)","(MYD88, -0.16)","(RELA, -0.201)"]
[958,"ceramide metabolism (GO:0006672)",5,0.692,1,1,"(PPP2R1B, 0.367)","(SGPL1, 0.23)","(NSMAF, -0.057)","(ASAH1, -0.15)","(CERK, -0.29)"]
[964,"clustering of voltage-gated sodium channels (GO:0045162)",2,0.693,1,0.99982,"(NRCAM, -0.042)","(AGRN, -0.172)"]
[964,"ST Differentiation Pathway in PC12 Cells Signalling Transduction KE",45,0.693,1,1,"(CAMP, 0.611)","(GAS, 0.39)","(TUBA3, 0.38)","(CREB3, 0.295)","(JUN, 0.295)","(CREB1, 0.268)","(TH, 0.237)","(PIK3C2G, 0.156)","(MAPK8IP2, 0.137)","(BRAF, 0.084)","(DAG1, 0.079)","(PTPN11, 0.049)","(MAPK8IP1, 0.03)","(NTRK1, 0.015)","(MAPK8, 0.002)","(MAPK3, 0)","(CREB5, 0)","(GNAQ, 0)","(MAPK1, 0)","(CREBBP, 0)","(PIK3R1, -0.006)","(ASAH1, -0.007)","(ATF1, -0.016)","(CRKL, -0.021)","(PACAP, -0.024)","(SH2B, -0.029)","(MAPK8IP3, -0.036)","(MAP2K7, -0.042)","(SRC, -0.045)","(MAP1B, -0.053)","(ELK1, -0.058)","(SHC1, -0.059)","(MAP2K4, -0.061)","(PIK3CA, -0.066)","(MAPK9, -0.077)","(EGR1, -0.088)","(RPS6KA3, -0.092)","(MAPK10, -0.093)","(AKT1, -0.099)","(EGR4, -0.108)","(FRS2, -0.108)","(EGR3, -0.126)","(TERF2IP, -0.137)","(EGR2, -0.143)","(PIK3CD, -0.184)"]
[966,"learning and/or memory (GO:0007611)",10,0.694,1,0.6589,"(CRHBP, 0.547)","(GRIN2B, 0.145)","(GRIN2A, 0.122)","(ADCY8, 0.067)","(GALR2, 0.044)","(IL1RAPL1, 0.009)","(S100B, -0.075)","(APOE, -0.113)","(ACSL4, -0.195)","(CRH, -0.216)"]
[966,"alkPathway Activin receptor-like kinase 3 (ALK3) is required during gestation for cardiac muscle development.",33,0.694,1,0.94398,"(ATF2, 0.348)","(RFC1, 0.329)","(TCF1, 0.315)","(TGFBR2, 0.233)","(BMP10, 0.191)","(GATA4, 0.162)","(GSK3B, 0.146)","(AXIN1, 0.13)","(BMP7, 0.12)","(BMPR2, 0.086)","(CHRD, 0.051)","(TGFBR3, 0.047)","(NPPB, 0.028)","(DVL1, 0.013)","(TGFBR1, 0.012)","(FZD1, 0.008)","(APC, 0)","(NPPA, 0)","(TGFB3, 0)","(BMP4, -0.007)","(MADH6, -0.03)","(BMPR1A, -0.03)","(TGFB1, -0.085)","(MAP3K7, -0.086)","(ACVR1, -0.087)","(MEF2C, -0.094)","(MYL2, -0.094)","(NKX2-5, -0.112)","(CTNNB1, -0.121)","(BMP2, -0.123)","(WNT1, -0.13)","(TGFB2, -0.137)","(BMP5, -0.16)"]
[966,"ccr3Pathway CCR3 is a G-protein coupled receptor that recruits eosinophils to inflammation sites via chemokine ligands.",22,0.694,1,0.98794,"(CFL1, 0.705)","(GNAS, 0.566)","(NOX1, 0.383)","(ROCK2, 0.196)","(PIK3C2G, 0.083)","(MAPK1, 0.07)","(RAF1, 0.024)","(MAPK3, 0.016)","(GNAQ, -0.035)","(HRAS, -0.053)","(GNB1, -0.062)","(PLCB1, -0.064)","(MAP2K1, -0.072)","(PTK2, -0.075)","(MYL2, -0.089)","(PRKCB1, -0.093)","(PRKCA, -0.108)","(CCL11, -0.108)","(LIMK1, -0.115)","(PPP1R12B, -0.132)","(GNGT1, -0.166)","(CCR3, -0.183)"]
[966,"pgc1aPathway BioCarta",22,0.694,1,1,"(SLC2A4, 0.733)","(HDAC5, 0.615)","(CAMK1G, 0.232)","(PPP3CC, 0.196)","(PPARA, 0.081)","(CAMK2A, 0.044)","(CAMK4, 0)","(CAMK2B, 0)","(PPP3CA, -0.009)","(CALM2, -0.018)","(MEF2B, -0.034)","(CAMK1, -0.038)","(YWHAH, -0.04)","(CAMK2G, -0.058)","(CALM1, -0.064)","(SYT1, -0.088)","(MEF2C, -0.097)","(MEF2A, -0.104)","(MEF2D, -0.111)","(CALM3, -0.118)","(PPP3CB, -0.159)","(ESRRA, -0.173)"]
[970,"N-terminal protein amino acid acetylation (GO:0006474)",3,0.695,1,1,"(ARD1A, 0.001)","(NARG1L, 0)","(NARG1, -0.001)"]
[971,"arfPathway Cyclin-dependent kinase inhibitor 2A is a tumor suppressor that induces G1 arrest and can activate the p53 pathway, leading to G2/M arrest.",15,0.696,1,0.5758,"(RB1, 0.344)","(RAC1, 0.327)","(POLR1D, 0.273)","(E2F1, 0.259)","(MYC, 0.137)","(TWIST1, 0.042)","(TP53, -0.015)","(POLR1B, -0.025)","(TBX2, -0.033)","(ABL1, -0.035)","(PIK3R1, -0.075)","(CDKN2A, -0.106)","(POLR1C, -0.125)","(MDM2, -0.137)","(PIK3CA, -0.155)"]
[972,"negative regulation of survival gene product activity (GO:0008634)",4,0.697,1,0.92622,"(BAX, 0.31)","(BNIP3L, -0.037)","(HRK, -0.095)","(BCL2L1, -0.247)"]
[972,"peptidyl-serine phosphorylation (GO:0018105)",3,0.697,1,0.98117,"(MAP3K12, 0.133)","(TDGF1, 0.09)","(MAP4K1, -0.047)"]
[972,"betaoxidationPathway BLACK",6,0.697,1,1,"(HADHA, 0.566)","(ECHS1, 0.147)","(ACADM, 0)","(ACAT1, -0.123)","(ACADS, -0.128)","(ACADL, -0.243)"]
[975,"striated muscle development (GO:0007519)",7,0.698,1,0.99475,"(CSRP3, 0.42)","(MYL6, 0.254)","(SVIL, 0.021)","(MYF6, -0.066)","(MYF5, -0.074)","(MYOG, -0.163)","(MYOD1, -0.255)"]
[976,"pregnancy (GO:0007565)",28,0.699,1,0.58127,"(FCGRT, 0.491)","(CSH2, 0.418)","(COL16A1, 0.402)","(CRHBP, 0.362)","(PSG9, 0.12)","(DSPG3, 0.113)","(BYSL, 0.11)","(ADM, 0.101)","(PSG3, 0.077)","(INSL4, 0.072)","(OVGP1, 0.058)","(TEAD3, 0.052)","(PSG1, 0.006)","(TAC3, -0.004)","(AGT, -0.005)","(LNPEP, -0.014)","(OXTR, -0.022)","(FSHB, -0.027)","(PSG4, -0.03)","(PZP, -0.033)","(ADCYAP1, -0.035)","(FLT1, -0.037)","(INDO, -0.049)","(CEACAM1, -0.059)","(CLIC5, -0.071)","(PTHLH, -0.096)","(CRH, -0.119)","(RLN2, -0.153)"]
[976,"MAP03020 RNA polymerase GenMAPP",17,0.699,1,1,"(POLR2G, 0.393)","(DOK4, 0.258)","(POLR2H, 0.132)","(POLR2L, 0.118)","(IGFBP7, 0.103)","(POLR2K, 0.096)","(POLR2I, 0.042)","(POLR2A, 0.01)","(POLR1B, -0.005)","(POLR2D, -0.011)","(POLR2E, -0.026)","(POLR2F, -0.027)","(POLR2J2, -0.054)","(POLR2C, -0.065)","(POLRMT, -0.077)","(POLR2J, -0.09)","(POLR2B, -0.227)"]
[976,"setPathway BioCarta",11,0.699,1,1,"(DFFB, 0.667)","(HMGB2, 0.213)","(NME1, 0.057)","(CREBBP, 0.04)","(GZMB, 0.02)","(DFFA, -0.049)","(SET, -0.077)","(APEX1, -0.127)","(ANP32A, -0.144)","(GZMA, -0.164)","(PRF1, -0.214)"]
[979,"neutral amino acid transport (GO:0015804)",4,0.701,1,0.9148,"(SLC43A1, 0.317)","(SLC1A4, 0.075)","(SLC7A10, 0.02)","(SLC1A5, -0.165)"]
[979,"pyk2Pathway BioCarta",28,0.701,1,1,"(PLCG1, 0.495)","(PTK2B, 0.478)","(JUN, 0.392)","(RAC1, 0.248)","(MAPK14, 0.227)","(MAPK3, 0.1)","(SOS1, 0.063)","(MAP2K2, 0.059)","(RAF1, 0.018)","(SRC, 0.007)","(CALM2, 0)","(MAP2K4, 0)","(MAP2K3, 0)","(MAPK1, 0)","(CALM1, -0.007)","(MAP2K1, -0.014)","(HRAS, -0.018)","(MAPK8, -0.02)","(SHC1, -0.021)","(CRKL, -0.03)","(PAK1, -0.042)","(GRB2, -0.052)","(MAP3K1, -0.059)","(PRKCB1, -0.086)","(GNAQ, -0.091)","(CALM3, -0.105)","(SYT1, -0.116)","(PRKCA, -0.119)"]
[981,"erk5Pathway Signaling between a tissue and its innervating axon stimulates retrograde transport via Trk receptors, which activate Erk5, which induces transcription of anti-apoptotic factors.",17,0.702,1,0.82476,"(PLCG1, 0.587)","(CREB1, 0.431)","(MAPK7, 0.193)","(MAPK3, 0.119)","(RPS6KA1, 0.071)","(NTRK1, 0.056)","(MEF2B, 0.019)","(MAPK1, 0)","(SHC1, -0.016)","(HRAS, -0.024)","(GRB2, -0.043)","(PIK3CA, -0.044)","(PIK3R1, -0.044)","(MEF2A, -0.076)","(MEF2D, -0.121)","(AKT1, -0.129)","(MEF2C, -0.155)"]
[981,"receptor clustering (GO:0043113)",2,0.702,1,0.92854,"(PRKCABP, 0.067)","(AGRN, -0.116)"]
[983,"plcdPathway BioCarta",5,0.703,1,0.74038,"(ADRA1B, 0.707)","(TGM2, -0.039)","(PLCD1, -0.067)","(PRKCB1, -0.132)","(PRKCA, -0.205)"]
[984,"macrophage activation (GO:0042116)",2,0.704,1,0.93425,"(TLR4, 0.432)","(TLR6, -0.314)"]
[985,"BMP signaling pathway (GO:0030509)",2,0.705,1,0.96366,"(SMAD1, 0.322)","(SMAD5, -0.257)"]
[985,"tRNA processing (GO:0008033)",3,0.705,1,0.98745,"(POP4, 0.447)","(SARS, -0.283)","(AARS, -0.409)"]
[987,"regulation of cyclin dependent protein kinase activity (GO:0000079)",30,0.706,1,0.48072,"(CKS2, 0.529)","(CDKN3, 0.191)","(CHEK1, 0.186)","(CDKN1B, 0.185)","(CDC37, 0.11)","(CCNA1, 0.109)","(CDKN1C, 0.099)","(CCNH, 0.082)","(MNAT1, 0.079)","(GTF2H1, 0.07)","(CDK5R2, 0.065)","(CCNT2, 0.052)","(PKMYT1, 0.037)","(ANAPC2, 0.026)","(CCNT1, 0.02)","(CDC25A, 0.018)","(CCNE2, -0.009)","(CDKN2D, -0.038)","(CDK7, -0.044)","(CCNK, -0.057)","(CDKN1A, -0.068)","(GADD45A, -0.074)","(CDKN2A, -0.082)","(CCNA2, -0.092)","(CCNG1, -0.094)","(CDK5RAP3, -0.094)","(CDKN2B, -0.125)","(CDK5R1, -0.14)","(CDC6, -0.165)","(CDC25C, -0.182)"]
[988,"neutrophilPathway BioCarta",8,0.707,1,0.73114,"(SELE, 0.467)","(ITGB2, 0.282)","(ITGAL, 0.109)","(ITGAM, 0.05)","(ICAM1, -0.12)","(CD44, -0.222)","(SELL, -0.223)","(PECAM1, -0.232)"]
[989,"erbb3Pathway Neuregulins bind to the receptor tyrosine kinases ErbB3 and ErbB4, surface-localized receptors whose overexpression induces tumor formation.",5,0.708,1,0.99129,"(EGF, 0.504)","(EGFR, -0.015)","(UBE2D1, -0.158)","(ERBB3, -0.197)","(NRG1, -0.251)"]
[990,"ctla4Pathway T cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APC's CD80 or 86.",20,0.709,1,0.97924,"(HLA-DRB1, 0.332)","(CD3E, 0.29)","(CD28, 0.24)","(CD86, 0.227)","(TRA@, 0.175)","(PTPN11, 0.096)","(PIK3R1, 0.039)","(HLA-DRA, 0.01)","(GRB2, 0.009)","(CD80, -0.011)","(ICOSL, -0.015)","(CD3G, -0.018)","(IL2, -0.057)","(CTLA4, -0.072)","(ICOS, -0.097)","(CD3D, -0.097)","(LCK, -0.097)","(CD3Z, -0.113)","(ITK, -0.121)","(PIK3CA, -0.155)"]
[990,"isoprenoid biosynthesis (GO:0008299)",2,0.709,1,1,"(IDI1, 0.058)","(MVK, -0.061)"]
[990,"d4gdiPathway D4-GDI inhibits the pro-apoptotic Rho GTPases and is cleaved by caspase-3.",13,0.709,1,1,"(JUN, 0.461)","(CASP3, 0.429)","(ADPRT, 0.117)","(GZMB, 0.096)","(CASP10, 0.095)","(ARHGAP5, 0.064)","(CYCS, 0.016)","(CASP1, 0.009)","(CASP8, -0.042)","(APAF1, -0.073)","(CASP9, -0.085)","(ARHGDIB, -0.097)","(PRF1, -0.123)"]
[993,"regulation of cell migration (GO:0030334)",2,0.71,1,0.93735,"(EGFL7, 0.15)","(PARD6B, -0.069)"]
[994,"embryonic pattern specification (GO:0009880)",2,0.711,1,0.96366,"(SMAD1, 0.335)","(SMAD5, -0.289)"]
[994,"DNA packaging (GO:0006323)",6,0.711,1,0.98267,"(TNP2, 0.384)","(HAT1, 0.089)","(PRM1, -0.012)","(NASP, -0.076)","(PRM2, -0.115)","(MYST3, -0.133)"]
[996,"double-strand break repair via nonhomologous end-joining (GO:0006303)",2,0.712,1,1,"(XRCC6, 0.001)","(MRE11A, -0.001)"]
[997,"transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0007178)",4,0.713,1,0.92623,"(ACVR1B, 0.312)","(BMPR2, 0.123)","(ACVR1, -0.114)","(ACVR2B, -0.122)"]
[997,"trkaPathway BioCarta",14,0.713,1,1,"(PLCG1, 0.634)","(KLK2, 0.634)","(NTRK1, 0.069)","(SOS1, 0.046)","(PIK3R1, -0.004)","(DPM2, -0.006)","(HRAS, -0.011)","(SHC1, -0.013)","(GRB2, -0.057)","(NGFB, -0.101)","(PRKCB1, -0.11)","(AKT1, -0.113)","(PRKCA, -0.164)","(PIK3CA, -0.166)"]
[999,"synaptic transmission (GO:0007268)",131,0.714,1,0.56926,"(P2RX1, 0.365)","(SCN1B, 0.338)","(SLC6A1, 0.296)","(GAD1, 0.275)","(KCNC4, 0.247)","(KCNMA1, 0.209)","(PCDHB11, 0.204)","(DOC2A, 0.2)","(UNC119, 0.17)","(DBH, 0.145)","(DRD1IP, 0.141)","(GRM5, 0.138)","(SLC1A1, 0.137)","(GABRR2, 0.115)","(OMP, 0.11)","(CHRNA4, 0.08)","(GRM4, 0.032)","(SYN2, 0.024)","(NPFF, 0.023)","(GRIN2B, 0.021)","(GABARAPL2, 0.02)","(CNP, 0.006)","(UTS2, 0)","(CHRNA5, 0)","(HCRTR1, 0)","(SYT1, 0)","(NCAM1, 0)","(GPR51, 0)","(PCDHB3, 0)","(GRM7, 0)","(SYT5, 0)","(GAD2, 0)","(HTR3A, 0)","(DRD3, 0)","(MAPK1, 0)","(GLRA1, 0)","(HTR7, 0)","(KCND2, 0)","(CHRNA6, 0)","(DRD2, 0)","(SCN11A, 0)","(DRD1, 0)","(SLC6A7, 0)","(KCNQ3, 0)","(GABRB2, 0)","(MOG, 0)","(NOVA1, 0)","(AKAP9, 0)","(SCN2B, 0)","(PIK4CA, 0)","(GRIK4, 0)","(HCRTR2, 0)","(SLC6A2, 0)","(KCNA1, 0)","(GRIA1, 0)","(KCNQ2, 0)","(GALR2, 0)","(AKAP5, 0)","(CPNE6, 0)","(HAP1, 0)","(GABRR1, 0)","(HTR1D, 0)","(GRIK1, 0)","(GABARAPL1, 0)","(GRM1, 0)","(BSN, 0)","(LARGE, 0)","(KCNK3, 0)","(APBA1, 0)","(CRH, 0)","(HTR1E, 0)","(DRD5, 0)","(KIF5A, 0)","(CACNA1E, 0)","(HTR2A, 0)","(HTR6, 0)","(CHRNA2, 0)","(HTR1F, 0)","(PMP22, 0)","(CNTF, 0)","(VIPR1, 0)","(SULT1A3, 0)","(NPTX1, 0)","(HTR2C, 0)","(GRIA2, 0)","(KCNN1, 0)","(GABARAP, 0)","(DLG4, 0)","(NOS1, 0)","(MBP, 0)","(KCNMB1, 0)","(SLC1A2, 0)","(NPY, 0)","(STRN4, 0)","(CBLN1, 0)","(HTR1B, 0)","(CORT, 0)","(CACNA1A, 0)","(MTNR1B, 0)","(CACNA1F, 0)","(GRM8, 0)","(GRIN2A, 0)","(SLC6A5, 0)","(GRM2, 0)","(CHRNA7, 0)","(DNM1, 0)","(HCRT, 0)","(HOMER1, 0)","(ACCN1, 0)","(MPZ, 0)","(RAPSN, 0)","(QPRT, 0)","(GALR1, 0)","(CHRNB1, 0)","(SLC1A6, 0)","(AMPH, 0)"]
[999,"phagocytosis, engulfment (GO:0006911)",3,0.714,1,0.95826,"(ELMO1, 0.058)","(DOCK1, -0.036)","(FCGR1A, -0.05)"]
[1001,"no1Pathway BioCarta",29,0.715,1,0.91741,"(SLC7A1, 0.365)","(PDE2A, 0.235)","(PRKAR2A, 0.231)","(PRKACB, 0.212)","(ACTA1, 0.17)","(PDE3B, 0.163)","(PDE3A, 0.156)","(FLT4, 0.14)","(PRKAR2B, 0.12)","(PRKAR1B, 0.076)","(CAV1, 0.023)","(BDKRB2, 0.018)","(KDR, 0.015)","(PRKG1, 0.006)","(CALM2, 0.001)","(CHRNA1, 0)","(CALM1, -0.008)","(PRKAR1A, -0.019)","(VEGF, -0.031)","(NOS3, -0.04)","(TNNI1, -0.054)","(FLT1, -0.073)","(AKT1, -0.087)","(PRKACG, -0.087)","(HSPCA, -0.097)","(CALM3, -0.098)","(PRKG2, -0.103)","(SYT1, -0.166)","(RYR2, -0.2)"]
[1002,"positive regulation of phosphorylation (GO:0042327)",2,0.718,1,0.99597,"(EGFR, 0.064)","(GLMN, -0.378)"]
[1003,"peripheral nervous system development (GO:0007422)",10,0.719,1,0.66667,"(NEUROG3, 0.413)","(UGT8, 0.225)","(ACCN1, 0.086)","(BAI1, 0.076)","(GFRA3, 0.021)","(PMP22, 0.005)","(EGR2, -0.091)","(SERPINI1, -0.102)","(MPZ, -0.142)","(ALDH3A2, -0.144)"]
[1003,"MAPK Cascade GO",23,0.719,1,1,"(JUN, 0.425)","(RRAS, 0.346)","(MAPK14, 0.245)","(MAP3K2, 0.124)","(ARAF1, 0.117)","(MAPK3, 0.053)","(BRAF, 0.034)","(MAPK1, -0.016)","(RAF1, -0.027)","(MAP3K3, -0.031)","(MAP2K1, -0.043)","(MAP2K4, -0.052)","(MAP2K3, -0.063)","(MAP2K7, -0.064)","(PLCB3, -0.071)","(D1S155E, -0.089)","(MBP, -0.089)","(MAP2, -0.091)","(MAP3K1, -0.096)","(NRAS, -0.097)","(MAPK10, -0.12)","(ELK1, -0.172)","(MAP2K6, -0.179)"]
[1005,"iron ion homeostasis (GO:0006879)",6,0.72,1,1,"(MYC, 0.275)","(FTL, 0.128)","(CP, 0.046)","(TFR2, -0.1)","(HFE, -0.144)","(HPX, -0.192)"]
[1006,"chromatin modification (GO:0016568)",7,0.724,1,0.92115,"(HDAC2, 0.207)","(HDAC4, 0.17)","(HDAC1, 0.139)","(HDAC3, 0.088)","(HDAC11, 0.019)","(HDAC7A, -0.123)","(EHMT1, -0.232)"]
[1006,"MAP00640 Propanoate metabolism GenMAPP",20,0.724,1,1,"(ALDH2, 0.595)","(MUT, 0.397)","(ABAT, 0.272)","(HADHA, 0.259)","(ECHS1, 0.137)","(C14orf45, 0.087)","(LDHB, 0.034)","(ACADM, 0.01)","(PCCA, -0.004)","(LDHC, -0.014)","(ACACA, -0.024)","(ALDH1B1, -0.025)","(ALDH1A1, -0.029)","(ACAT1, -0.048)","(ALDH3A2, -0.05)","(LDHA, -0.066)","(PCCB, -0.067)","(ALDH6A1, -0.092)","(EHHADH, -0.175)","(ACACB, -0.199)"]
[1008,"MAP00630 Glyoxylate and dicarboxylate metabolism GenMAPP",10,0.725,1,0.61133,"(MTHFD2, 1.155)","(MDH1, 0.136)","(GRHPR, -0.02)","(ACO2, -0.071)","(MDH2, -0.114)","(CS, -0.147)","(HAO2, -0.191)","(MTHFD1, -0.205)","(HAO1, -0.248)","(ACO1, -0.263)"]
[1008,"gluconeogenesis (GO:0006094)",3,0.725,1,0.77123,"(ATF4, 0.148)","(SLC25A10, 0.071)","(COQ7, -0.178)"]
[1008,"MAP00790 Folate biosynthesis GenMAPP",12,0.725,1,1,"(GGH, 0.499)","(PTS, 0.412)","(ALPPL2, 0.355)","(DHFR, 0.24)","(ALPP, -0.006)","(FPGS, -0.02)","(GCH1, -0.043)","(ALPI, -0.099)","(ALPL, -0.111)","(TYMS, -0.162)","(QDPR, -0.197)","(MTHFD1, -0.199)"]
[1011,"GPCRs Class B Secretin-like GO",24,0.726,1,0.56468,"(GHRHR, 0.448)","(GLP1R, 0.245)","(SCTR, 0.188)","(VIPR2, 0.183)","(LPHN2, 0.141)","(ELTD1, 0.129)","(ADCYAP1R1, 0.129)","(GCGR, 0.113)","(CD97, 0.077)","(GLP2R, 0.056)","(PTHR2, 0.031)","(CRHR2, 0.03)","(EMR1, 0.024)","(LPHN1, 0.015)","(CRHR1, -0.008)","(GPR64, -0.01)","(CMKOR1, -0.063)","(GIPR, -0.091)","(CALCR, -0.094)","(PTHR1, -0.095)","(LPHN3, -0.101)","(CALCRL, -0.116)","(EMR2, -0.121)","(VIPR1, -0.127)"]
[1011,"inactivation of MAPK activity (GO:0000188)",10,0.726,1,0.90086,"(PPP2R1B, 0.311)","(GPS1, 0.17)","(RGS4, 0.147)","(RGS3, 0.04)","(DUSP2, 0.011)","(DUSP8, -0.017)","(DUSP6, -0.031)","(GPS2, -0.033)","(DUSP9, -0.105)","(SPRED2, -0.122)"]
[1011,"fatty acid catabolism (GO:0009062)",3,0.726,1,0.92583,"(PPARD, 0.397)","(PCCB, -0.117)","(LYPLA3, -0.265)"]
[1014,"eosinophilsPathway Recruitment of eosinophils in the inflammatory response observed in asthma occurs via the chemoattractant eotaxin binding to the CCR3 receptor.",8,0.728,1,0.87163,"(HLA-DRB1, 0.484)","(CSF2, 0.197)","(IL5, 0.074)","(HLA-DRA, -0.021)","(IL3, -0.057)","(CCL11, -0.08)","(CCL5, -0.173)","(CCR3, -0.239)"]
[1014,"vesicle fusion (GO:0006906)",2,0.728,1,0.88574,"(STX6, 0.169)","(EEA1, -0.326)"]
[1016,"aerobic respiration (GO:0009060)",7,0.729,1,0.75487,"(SURF1, 0.88)","(UQCRH, 0.023)","(UQCRB, -0.11)","(SLC25A14, -0.166)","(UQCRC2, -0.184)","(UQCRC1, -0.206)","(OXA1L, -0.212)"]
[1016,"neutrophil chemotaxis (GO:0030593)",4,0.729,1,0.9713,"(ITGB2, 0.441)","(CKLF, -0.094)","(IL8, -0.105)","(SYK, -0.318)"]
[1016,"srcRPTPPathway BioCarta",11,0.729,1,1,"(CSK, 0.653)","(PTPRA, 0.364)","(CDC25B, 0.12)","(SRC, 0.042)","(GRB2, -0.004)","(CDC25A, -0.013)","(CDC2, -0.016)","(CCNB1, -0.016)","(PRKCB1, -0.127)","(PRKCA, -0.143)","(CDC25C, -0.195)"]
[1019,"vesicle-mediated transport (GO:0016192)",24,0.73,1,0.51668,"(CPNE3, 0.563)","(RAB13, 0.523)","(PRKCI, 0.135)","(SEC23B, 0.133)","(M6PRBP1, 0.13)","(LRPAP1, 0.101)","(TRAPPC4, 0.065)","(CPNE6, 0.064)","(MAPK8IP1, 0.059)","(CPNE1, 0.048)","(GOLGA4, 0.007)","(SPTBN2, -0.024)","(VPS4A, -0.075)","(MAPK8IP3, -0.086)","(SEC24B, -0.09)","(PSCD1, -0.091)","(ARF6, -0.093)","(PSCD3, -0.094)","(SPTBN4, -0.095)","(SEC23A, -0.099)","(PCOLN3, -0.124)","(SYTL2, -0.145)","(KIF20A, -0.157)","(VTI1B, -0.184)"]
[1019,"regulation of transcription (GO:0045449)",7,0.73,1,0.96072,"(PPP2R1B, 0.367)","(APBB2, 0.131)","(PPIE, 0.112)","(APBB1, 0.03)","(HCFC1, 0.004)","(BRCA2, -0.174)","(FUSIP1, -0.325)"]
[1021,"pmlPathway BioCarta",15,0.731,1,0.53409,"(RB1, 0.388)","(TNFRSF1A, 0.36)","(TNFSF6, 0.136)","(TNFRSF6, 0.122)","(RARA, 0.075)","(PML, 0.026)","(DAXX, -0.007)","(CREBBP, -0.023)","(SIRT1, -0.023)","(SP100, -0.024)","(TNF, -0.039)","(HRAS, -0.04)","(TP53, -0.065)","(PAX3, -0.068)","(TNFRSF1B, -0.171)"]
[1022,"MYC WT Myc wild type",9,0.732,1,0.79784,"(IVNS1ABP, 0.493)","(VPS45A, 0.113)","(KIAA0652, 0.081)","(KCNJ10, -0.071)","(SIRT2, -0.073)","(YPEL1, -0.079)","(CASK, -0.09)","(UQCRC1, -0.21)","(ACTR2, -0.234)"]
[1023,"eif4Pathway The eIF-4F complex recognizes 5' mRNA caps, recruits RNA helicases, and maintains mRNA-ribosome bridging.",24,0.733,1,0.99578,"(RPS6KB1, 0.68)","(EIF4G3, 0.208)","(MAPK14, 0.172)","(PABPC1, 0.156)","(GHR, 0.135)","(IRS1, 0.084)","(EIF4A1, 0.058)","(PDPK1, 0.046)","(MAPK3, 0.044)","(MAPK1, 0.039)","(FRAP1, 0.034)","(PDK2, 0.013)","(EIF4G2, 0.012)","(PIK3R1, -0.035)","(PRKCB1, -0.04)","(EIF4E, -0.063)","(EIF4G1, -0.07)","(MKNK1, -0.078)","(PTEN, -0.152)","(AKT1, -0.156)","(PIK3CA, -0.161)","(PRKCA, -0.17)","(EIF4A2, -0.198)","(EIF4EBP1, -0.203)"]
[1024,"calcineurinPathway Increased intracellular calcium activates the phosphatase calcineurin in differentiating keratinocytes.",18,0.734,1,0.62356,"(PLCG1, 0.64)","(NFATC1, 0.4)","(PPP3CC, 0.207)","(NFATC3, 0.205)","(SP3, 0.088)","(CALM1, 0.041)","(PPP3CA, 0)","(CALM2, -0.032)","(GNAQ, -0.082)","(MARCKS, -0.096)","(CALM3, -0.146)","(CDKN1A, -0.156)","(PPP3CB, -0.156)","(PRKCB1, -0.16)","(PRKCA, -0.165)","(SYT1, -0.179)","(NFATC4, -0.2)","(SP1, -0.218)"]
[1024,"apoptotic mitochondrial changes (GO:0008637)",4,0.734,1,0.97367,"(BAX, 0.322)","(BAK1, 0.155)","(BCL2L1, -0.218)","(BID, -0.237)"]
[1026,"nuclear mRNA splicing, via spliceosome (GO:0000398)",6,0.735,1,0.988,"(DHX38, 0.674)","(BAT1, 0.152)","(TRA2A, 0.046)","(DDX39, -0.17)","(SFRS10, -0.214)","(FUSIP1, -0.349)"]
[1027,"melanin biosynthesis from tyrosine (GO:0006583)",2,0.736,1,0.92799,"(DCT, 0.094)","(TYR, -0.343)"]
[1027,"badPathway When phosphorylated, BAD is inhibited by sequestration; when non-phosphorylated, it promotes apoptosis by inactivating pro-survival BCL-XL and BCL-2.",22,0.736,1,1,"(IL3RA, 0.404)","(BAX, 0.172)","(PRKAR2A, 0.133)","(PRKAR2B, 0.124)","(BAD, 0.119)","(PRKACB, 0.11)","(ADCY1, 0.109)","(IGF1, 0.069)","(PRKAR1B, 0.057)","(BCL2, 0.054)","(IL3, 0.02)","(IGF1R, -0.011)","(CSF2RB, -0.014)","(PIK3R1, -0.015)","(YWHAH, -0.03)","(KITLG, -0.041)","(PRKACG, -0.093)","(BCL2L1, -0.098)","(KIT, -0.104)","(PIK3CA, -0.11)","(AKT1, -0.116)","(PRKAR1A, -0.188)"]
[1027,"ptc1Pathway BioCarta",11,0.736,1,1,"(CCNH, 0.282)","(CDC25B, 0.144)","(XPO1, 0.095)","(SHH, 0.073)","(MNAT1, 0.05)","(CDC25A, 0.015)","(CDC2, -0.078)","(PTCH, -0.088)","(CDC25C, -0.089)","(CCNB1, -0.094)","(CDK7, -0.112)"]
[1030,"determination of anterior/posterior axis, embryo (GO:0008595)",2,0.737,1,0.92971,"(TDGF1, 0.139)","(T, -0.46)"]
[1030,"plk3Pathway BioCarta",7,0.737,1,0.96058,"(ATR, 0.321)","(CHEK1, 0.249)","(YWHAH, 0.076)","(ATM, -0.015)","(TP53, -0.019)","(CHEK2, -0.019)","(CDC25C, -0.213)"]
[1030,"sperm motility (GO:0030317)",6,0.737,1,0.99344,"(TNP1, 0.487)","(GAS8, 0.205)","(ATP1A3, -0.035)","(MCSP, -0.074)","(ATP1A1, -0.209)","(ATP1A2, -0.253)"]
[1033,"transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169)",23,0.738,1,0.68182,"(LCP2, 0.199)","(FLT4, 0.192)","(GFRA2, 0.185)","(PTPRG, 0.18)","(PTPRT, 0.175)","(ROR1, 0.116)","(MTSS1, 0.109)","(EDN2, 0.08)","(NTRK2, 0.052)","(ABI1, 0.026)","(NTRK1, 0.023)","(BDKRB2, 0.019)","(NRTN, -0.004)","(RAPGEF1, -0.006)","(DOK1, -0.008)","(PTPRJ, -0.018)","(NTRK3, -0.045)","(CNKSR1, -0.057)","(FLT1, -0.074)","(TEK, -0.09)","(FLT3, -0.099)","(KDR, -0.118)","(MUSK, -0.12)"]
[1033,"mRNA binding activity BioCarta",9,0.738,1,0.99148,"(ELAVL1, 0.25)","(EIF4A1, 0.129)","(FMR1, 0.097)","(GRSF1, 0.082)","(SLBP, 0.058)","(RPL35, -0.004)","(HNRPAB, -0.059)","(SSB, -0.179)","(KHDRBS1, -0.222)"]
[1035,"igf1Pathway BioCarta",20,0.739,1,1,"(JUN, 0.438)","(SRF, 0.251)","(IGF1, 0.167)","(FOS, 0.16)","(PTPN11, 0.08)","(IRS1, 0.078)","(MAPK3, 0.055)","(SOS1, 0.015)","(RAF1, 0.013)","(SHC1, 0.011)","(GRB2, -0.005)","(PIK3R1, -0.017)","(MAPK8, -0.025)","(HRAS, -0.076)","(PIK3CA, -0.085)","(MAP2K1, -0.087)","(IGF1R, -0.116)","(ELK1, -0.138)","(RASA1, -0.177)","(CSNK2A1, -0.184)"]
[1036,"pelp1Pathway BioCarta",7,0.74,1,0.89224,"(MAPK3, 0.122)","(ESR1, 0.07)","(PELP1, 0.051)","(SRC, 0.04)","(EP300, -0.003)","(MAPK1, -0.029)","(CREBBP, -0.089)"]
[1037,"mtorPathway BioCarta",23,0.741,1,1,"(RPS6KB1, 0.695)","(PPP2CA, 0.334)","(TSC1, 0.28)","(FKBP1A, 0.233)","(EIF4G3, 0.226)","(EIF4A1, 0.132)","(PDPK1, 0.114)","(PDK2, 0.047)","(EIF4G2, 0.022)","(FRAP1, -0.013)","(PIK3R1, -0.053)","(EIF4G1, -0.064)","(RPS6, -0.069)","(EIF4E, -0.077)","(EIF3S10, -0.086)","(PIK3CA, -0.091)","(TSC2, -0.092)","(MKNK1, -0.105)","(EIF4B, -0.11)","(AKT1, -0.143)","(EIF4EBP1, -0.145)","(EIF4A2, -0.151)","(PTEN, -0.162)"]
[1038,"lymphocytePathway BioCarta",9,0.742,1,0.91169,"(SELE, 0.435)","(ITGB2, 0.263)","(ITGA4, 0.234)","(ITGAL, 0.203)","(ITGB1, -0.029)","(ICAM1, -0.162)","(CD44, -0.234)","(SELL, -0.236)","(PECAM1, -0.244)"]
[1038,"CR DNA MET AND MOD PNAS 2007",24,0.742,1,1,"(CHC1, 0.276)","(DNMT1, 0.274)","(OAS1, 0.268)","(MLL, 0.263)","(TERT, 0.227)","(TERF1, 0.18)","(ADK, 0.136)","(MCM4, 0.126)","(MBD2, 0.062)","(LIG1, 0.041)","(RFC4, 0.035)","(POLB, 0.015)","(S100A11, 0.01)","(TEP1, -0.004)","(MBD4, -0.023)","(LIG3, -0.039)","(TERF2IP, -0.081)","(DNMT2, -0.092)","(HMGA2, -0.093)","(RFC3, -0.125)","(HMGA1, -0.13)","(NME6, -0.131)","(TK2, -0.134)","(PCAF, -0.138)"]
[1040,"induction of apoptosis by extracellular signals (GO:0008624)",15,0.743,1,0.59908,"(BTK, 0.477)","(DAPK1, 0.22)","(CD38, 0.213)","(BAX, 0.16)","(DPF2, 0.122)","(SIVA, 0.014)","(DAP3, -0.006)","(MAP3K5, -0.037)","(CFLAR, -0.057)","(ADORA1, -0.067)","(PDCD6, -0.076)","(PRKCA, -0.09)","(TNFRSF25, -0.125)","(FASTK, -0.175)","(DAP, -0.235)"]
[1041,"integrinPathway BioCarta",34,0.744,1,0.89304,"(JUN, 0.374)","(CSK, 0.343)","(TNS, 0.336)","(ACTA1, 0.23)","(CAPNS1, 0.202)","(FYN, 0.131)","(VCL, 0.107)","(MAP2K2, 0.067)","(ROCK1, 0.067)","(ACTN3, 0.061)","(RAF1, 0.043)","(CAV1, 0.038)","(ITGB1, 0.03)","(SOS1, 0.013)","(GRB2, 0.012)","(SHC1, 0.004)","(ZYX, 0)","(MAPK1, 0)","(SRC, -0.006)","(MAPK3, -0.012)","(CRKL, -0.026)","(MAPK8, -0.026)","(HRAS, -0.035)","(MAP2K1, -0.037)","(CAPN1, -0.046)","(TLN1, -0.055)","(BCR, -0.065)","(ACTN1, -0.085)","(PXN, -0.099)","(RAP1A, -0.11)","(PTK2, -0.117)","(ACTN2, -0.125)","(PPP1R12B, -0.146)","(ITGA1, -0.176)"]
[1041,"glycosaminoglycan catabolism (GO:0006027)",3,0.744,1,0.8957,"(GNS, 0.074)","(GUSB, 0.07)","(HYAL2, -0.259)"]
[1041,"vegfPathway BioCarta",26,0.744,1,1,"(PLCG1, 0.503)","(HIF1A, 0.475)","(EIF2S2, 0.258)","(EIF2B5, 0.236)","(EIF2B2, 0.166)","(FLT4, 0.124)","(ELAVL1, 0.106)","(VHL, 0.037)","(HRAS, 0.028)","(VEGF, 0.022)","(EIF2B4, 0.007)","(PIK3R1, 0)","(SHC1, 0)","(ARNT, -0.042)","(PXN, -0.06)","(NOS3, -0.066)","(PRKCA, -0.073)","(KDR, -0.088)","(PTK2, -0.103)","(EIF2B1, -0.104)","(PIK3CA, -0.112)","(PRKCB1, -0.132)","(EIF2S1, -0.154)","(EIF2B3, -0.168)","(FLT1, -0.19)","(EIF2S3, -0.199)"]
[1044,"sodium ion transport (GO:0006814)",22,0.745,1,0.60593,"(SCN1B, 0.751)","(SLC8A1, 0.319)","(SCNN1G, 0.278)","(SCN4A, 0.253)","(SCNN1B, 0.171)","(SLC17A2, 0.118)","(SCNN1D, 0.036)","(ATP1A3, 0.02)","(SGK, 0.01)","(SCN5A, 0.001)","(SCN11A, -0.026)","(TMEM1, -0.037)","(SCN9A, -0.055)","(SCNN1A, -0.059)","(SCN10A, -0.07)","(SCN7A, -0.074)","(SCN2B, -0.078)","(SLC9A6, -0.09)","(SLC17A3, -0.098)","(ATP1A1, -0.119)","(SCN2A2, -0.158)","(ATP1A2, -0.166)"]
[1044,"pyrimidine nucleotide metabolism (GO:0006220)",3,0.745,1,0.78702,"(DCK, 0.143)","(ECGF1, 0.02)","(DCTD, -0.158)"]
[1044,"akap96Pathway BioCarta",12,0.745,1,1,"(PPP2CA, 0.413)","(PRKACB, 0.277)","(PRKAR2A, 0.276)","(PRKAR2B, 0.166)","(AKAP8, 0.069)","(CNAP1, 0.021)","(CDC2, 0.01)","(PRKAG1, -0.031)","(CCNB1, -0.066)","(PPP1CA, -0.107)","(PRKACG, -0.109)","(DDX5, -0.174)"]
[1047,"krebPathway BioCarta",8,0.746,1,0.87059,"(SUCLA2, 0.306)","(MDH1, 0.204)","(SDHA, 0.079)","(OGDH, -0.014)","(IDH2, -0.072)","(CS, -0.119)","(ACO2, -0.195)","(FH, -0.305)"]
[1048,"protein targeting to lysosome (GO:0006622)",2,0.749,1,0.76165,"(ZFYVE16, 0.16)","(NAGPA, -0.275)"]
[1049,"mRNA splicing BioCarta",51,0.751,1,0.62526,"(SRP19, 0.471)","(SF3A3, 0.334)","(SF3B4, 0.293)","(SNRPG, 0.269)","(IVNS1ABP, 0.224)","(LSM1, 0.207)","(SFRS2, 0.159)","(SF3A2, 0.151)","(PRPF18, 0.103)","(SMNDC1, 0.094)","(NOL3, 0.09)","(PRPF4, 0.061)","(LSM6, 0.056)","(NONO, 0.031)","(PRPF8, 0.023)","(PTBP1, 0.008)","(DDX23, 0.007)","(SNRPD1, 0)","(SFPQ, 0)","(SFRS2IP, 0)","(SNRPF, 0)","(KHSRP, 0)","(SNRPB, 0)","(SNRPD3, 0)","(SNRPA1, 0)","(SNRPB2, 0)","(HNRPC, 0)","(SRRM1, 0)","(FNBP3, 0)","(PPAN, 0)","(U2AF1, -0.009)","(SNRPN, -0.011)","(NP220, -0.015)","(SFRS11, -0.023)","(SNRP70, -0.024)","(USP39, -0.037)","(PRPF3, -0.045)","(SFRS10, -0.045)","(LSM4, -0.046)","(U2AF1L2, -0.053)","(SNRPD2, -0.062)","(SF3B3, -0.066)","(SF3A1, -0.073)","(SFRS4, -0.081)","(CDC40, -0.095)","(HPRP8BP, -0.112)","(MPHOSPH10, -0.115)","(PPIG, -0.115)","(SNRPC, -0.126)","(NCBP1, -0.134)","(SFRS7, -0.209)"]
[1049,"il3Pathway BioCarta",15,0.751,1,0.85676,"(IL3RA, 0.489)","(FOS, 0.146)","(SOS1, 0.06)","(RAF1, 0.058)","(MAPK3, 0.042)","(STAT5B, 0.03)","(GRB2, 0.023)","(STAT5A, 0.004)","(IL3, 0.001)","(CSF2RB, -0.002)","(SHC1, -0.024)","(PTPN6, -0.06)","(HRAS, -0.082)","(MAP2K1, -0.086)","(JAK2, -0.202)"]
[1049,"regulation of progression through cell cycle (GO:0000074)",105,0.751,1,0.92642,"(MPHOSPH6, 0.389)","(HDAC5, 0.324)","(SLC12A4, 0.308)","(SFN, 0.224)","(PTMS, 0.218)","(CSK, 0.213)","(MKI67, 0.209)","(PLK3, 0.178)","(DHX16, 0.167)","(CDC14A, 0.166)","(PIK3CB, 0.151)","(PPP2R1B, 0.122)","(CCNC, 0.107)","(PPP2CA, 0.089)","(CDC25B, 0.063)","(MNT, 0.024)","(CDK8, 0.016)","(PPP2R1A, 0.006)","(ANAPC5, 0)","(RHOG, 0)","(BCL2, 0)","(CDC2L2, 0)","(PRKG2, 0)","(DKC1, 0)","(CUL5, 0)","(CIZ1, 0)","(CDC42, 0)","(AXL, 0)","(GAK, 0)","(HCFC1, 0)","(MPHOSPH9, 0)","(PTMA, 0)","(NFYC, 0)","(MDM2, 0)","(PSMD8, 0)","(FRAP1, 0)","(ABL1, 0)","(BCL3, 0)","(FRK, 0)","(ATF5, 0)","(PCTK1, 0)","(FZR1, 0)","(JAK2, 0)","(PHB, 0)","(SPHAR, 0)","(CDK6, 0)","(TCF7L2, 0)","(PRKCA, 0)","(MTCP1, 0)","(PPM1D, 0)","(YWHAQ, 0)","(STAT1, 0)","(NHP2L1, 0)","(BRCA2, 0)","(IGF1R, 0)","(RPS6KB2, 0)","(PCTK2, 0)","(NOL1, 0)","(ACPP, 0)","(CCT7, 0)","(CDC20, 0)","(PLK1, 0)","(WEE1, 0)","(HDAC9, 0)","(E2F4, 0)","(ANAPC10, 0)","(CCNF, 0)","(MAPRE1, 0)","(POLR3D, 0)","(MCM5, 0)","(CDK3, 0)","(F2R, 0)","(HDAC7A, 0)","(MCRS1, 0)","(DNAJA2, 0)","(SKP2, 0)","(BTG3, 0)","(UBE2V2, 0)","(HDAC3, 0)","(CCND3, 0)","(IFITM1, 0)","(CDK4, 0)","(NEDD9, 0)","(ERH, 0)","(GML, 0)","(MATK, 0)","(TOB2, 0)","(TFDP1, 0)","(CCT4, 0)","(F2, 0)","(SCAND1, 0)","(CDKL1, 0)","(TP53BP2, 0)","(CLK1, 0)","(HK2, 0)","(ERF, 0)","(UBE2V1, 0)","(E2F5, 0)","(TNFSF15, 0)","(TTK, 0)","(IL2RA, 0)","(CDC2L1, 0)","(CDK9, 0)","(ARHGEF1, 0)","(ESPL1, 0)"]
[1049,"DNA replication checkpoint (GO:0000076)",3,0.751,1,0.93499,"(CDT1, 0.455)","(CDC45L, -0.345)","(CDC6, -0.377)"]
[1053,"SA MMP CYTOKINE CONNECTION SigmaAldrich",15,0.752,1,1,"(IL6R, 0.452)","(CSF1, 0.334)","(TNFRSF1A, 0.321)","(TNFSF8, 0.292)","(TNFRSF8, 0.194)","(IL1B, 0.099)","(TGFB2, -0.062)","(FCGR3A, -0.064)","(TNF, -0.077)","(ACE, -0.093)","(TGFB1, -0.127)","(SPN, -0.129)","(SELL, -0.145)","(TNFRSF1B, -0.148)","(CD44, -0.15)"]
[1054,"peptide hormone processing (GO:0016486)",2,0.753,1,0.93106,"(ECE2, -0.034)","(SGNE1, -0.139)"]
[1054,"tertPathway BioCarta",8,0.753,1,1,"(MYC, 0.204)","(HDAC1, 0.108)","(SP3, 0.076)","(TP53, -0.031)","(WT1, -0.084)","(ZNF42, -0.127)","(MAX, -0.174)","(SP1, -0.222)"]
[1056,"cell cycle (GO:0007049)",13,0.754,1,0.77404,"(CUL7, 0.358)","(ATR, 0.294)","(ERBB2IP, 0.133)","(GPS1, 0.046)","(DTYMK, 0.035)","(AHR, 0.028)","(STRN3, 0.027)","(UBA52, -0.004)","(GPS2, -0.04)","(NOLC1, -0.089)","(MCM2, -0.112)","(PFDN1, -0.16)","(USP16, -0.169)"]
[1056,"CBF LEUKEMIA DOWNING AML Manually Curated",75,0.754,1,0.95061,"(PMAIP1, 0.367)","(CYLN2, 0.316)","(HIF1A, 0.304)","(WFDC1, 0.275)","(HOMER2, 0.218)","(GALNT14, 0.214)","(PTGER2, 0.212)","(IL15RA, 0.21)","(VAMP5, 0.2)","(SIPA1L1, 0.165)","(MAN1A1, 0.143)","(CLECSF5, 0.141)","(CD34, 0.13)","(TRH, 0.114)","(ABR, 0.104)","(HLA-DPB1, 0.076)","(NARFL, 0.065)","(DEXI, 0.051)","(HLA-DPA1, 0.022)","(DNMT3B, 0.019)","(RASA4, 0.009)","(CAV1, 0.008)","(BAALC, 0.006)","(PURA, 0.004)","(MN1, 0)","(ADCY7, 0)","(PGDS, 0)","(NCALD, 0)","(CACNA2D2, 0)","(TPK1, 0)","(SPARC, 0)","(ROBO1, 0)","(ISG20, 0)","(DUSP2, 0)","(IL5RA, 0)","(PIK4CA, 0)","(TRIM8, 0)","(EGLN1, 0)","(CBFB, 0)","(WASPIP, 0)","(SYNGR1, 0)","(MKNK2, 0)","(MHC2TA, 0)","(ADARB1, 0)","(DUSP6, 0)","(CRIP2, 0)","(DHRS8, 0)","(C11orf21, 0)","(BLVRA, 0)","(CDW52, 0)","(JUNB, 0)","(ITGB4, 0)","(CD58, 0)","(ATP2B4, 0)","(TBXA2R, 0)","(PRAME, 0)","(POU4F1, 0)","(EGFL7, 0)","(DISC1, 0)","(MGC3222, 0)","(HYAL2, 0)","(MYH11, 0)","(SLC25A1, 0)","(BAIAP3, 0)","(HLA-DMB, 0)","(DKFZP434H132, 0)","(PGM1, 0)","(CCND3, 0)","(WBSCR5, 0)","(OGG1, -0.008)","(RCBTB1, -0.011)","(CBFA2T1, -0.016)","(TPSB2, -0.106)","(TRIO, -0.113)","(PTGIR, -0.204)"]
[1056,"long-term strengthening of neuromuscular junction (GO:0042062)",2,0.754,1,0.98496,"(UBA52, 0.005)","(COL4A4, -0.247)"]
[1059,"MAP00450 Selenoamino acid metabolism GenMAPP",6,0.755,1,0.92906,"(MAT1A, 0.524)","(GGT1, -0.034)","(CBS, -0.038)","(MARS, -0.04)","(AHCY, -0.126)","(CTH, -0.203)"]
[1059,"cdk5Pathway Cdk5, a regulatory kinase implicated in neuronal development, represses Mek1, which downregulates the MAP kinase pathway.",13,0.755,1,1,"(KLK2, 0.64)","(NGFR, 0.16)","(MAPK3, 0.085)","(MAP2K2, 0.048)","(RAF1, 0.029)","(DPM2, 0.004)","(MAPK1, -0.015)","(HRAS, -0.036)","(CDK5, -0.047)","(NGFB, -0.066)","(MAP2K1, -0.132)","(EGR1, -0.175)","(CDK5R1, -0.2)"]
[1061,"negative regulation of anti-apoptosis (GO:0019987)",2,0.757,1,0.99391,"(PIK3R2, 0.031)","(RTN4, -0.096)"]
[1062,"protein biosynthesis (GO:0006412)",46,0.758,1,0.95604,"(RPLP2, 0.43)","(RPL18A, 0.301)","(MRPL3, 0.271)","(RPS12, 0.211)","(ASMT, 0.182)","(MRPL19, 0.176)","(COPS5, 0.148)","(MRPL12, 0.128)","(ABCF1, 0.121)","(RPS27, 0.057)","(RPL4, 0.049)","(RPS3, 0.036)","(RPL34, 0.025)","(DARS, 0.021)","(RPL18, 0.014)","(DHPS, 0.013)","(RPS19, 0.009)","(RPS4Y1, 0.008)","(RPL14, 0)","(RPL28, 0)","(RPL3L, 0)","(RPLP0, 0)","(RPS5, 0)","(RPL13, 0)","(RPS6KB2, 0)","(RPS17, 0)","(PET112L, 0)","(RPL3, -0.002)","(RPL9, -0.008)","(RPL6, -0.01)","(RPS2, -0.017)","(RPLP1, -0.019)","(PABPC4, -0.026)","(RPL5, -0.037)","(WARS, -0.065)","(RPL19, -0.066)","(RPL35, -0.075)","(RPS9, -0.082)","(SARS, -0.089)","(RPL29, -0.098)","(RPL7, -0.118)","(RRBP1, -0.118)","(RPL27A, -0.125)","(RPL22, -0.132)","(RPL21, -0.153)","(RPS10, -0.159)"]
[1062,"ifngPathway BLACK",6,0.758,1,1,"(IFNGR1, 0.425)","(JAK1, 0.126)","(STAT1, 0.102)","(IFNGR2, -0.057)","(IFNG, -0.139)","(JAK2, -0.227)"]
[1062,"rbPathway BioCarta",13,0.758,1,1,"(RB1, 0.403)","(CDC25B, 0.188)","(CHEK1, 0.116)","(MYT1, 0.068)","(CDC25A, 0.067)","(TP53, 0.016)","(YWHAH, -0.02)","(WEE1, -0.032)","(CDC2, -0.063)","(ATM, -0.064)","(CDK2, -0.127)","(CDK4, -0.148)","(CDC25C, -0.175)"]
[1065,"mesoderm development (GO:0007498)",16,0.759,1,0.81242,"(BTK, 0.42)","(FOXC2, 0.283)","(TBX6, 0.255)","(SECTM1, 0.205)","(BMP4, 0.103)","(TCF15, 0.075)","(BMX, 0.052)","(INHBA, 0.046)","(JAK3, -0.02)","(GDF11, -0.069)","(TCF21, -0.128)","(HCK, -0.132)","(MATK, -0.132)","(ZNFN1A1, -0.162)","(JAK2, -0.162)","(T, -0.174)"]
[1065,"meiotic recombination (GO:0007131)",17,0.759,1,0.85006,"(RAD21, 0.49)","(MSH5, 0.163)","(REC8L1, 0.141)","(CHEK1, 0.116)","(RAD51L3, 0.104)","(RAD50, 0.093)","(DMC1, 0.076)","(RAD52, 0.015)","(LIG3, -0.023)","(ATM, -0.026)","(SPO11, -0.068)","(MSH4, -0.085)","(MRE11A, -0.092)","(SYCP1, -0.11)","(RAD51L1, -0.123)","(RAD51, -0.181)","(RAD54B, -0.196)"]
[1067,"neurotransmitter metabolism (GO:0042133)",4,0.76,1,0.79336,"(GCHFR, 0.249)","(PHOX2A, 0.05)","(TDO2, -0.149)","(GCH1, -0.174)"]
[1067,"mef2dPathway BioCarta",18,0.76,1,1,"(NFATC1, 0.39)","(TRA@, 0.246)","(PPP3CC, 0.241)","(CAPNS1, 0.213)","(CAPN2, 0.166)","(CALM1, 0.057)","(EP300, 0.055)","(HDAC2, 0.045)","(HDAC1, 0.038)","(CALM2, -0.014)","(PPP3CA, -0.019)","(PRKCB1, -0.085)","(MEF2D, -0.153)","(PRKCA, -0.155)","(SYT1, -0.155)","(PPP3CB, -0.167)","(CALM3, -0.181)","(CABIN1, -0.189)"]
[1067,"il22bpPathway BioCarta",12,0.76,1,1,"(IL22RA1, 0.354)","(IL22, 0.255)","(JAK1, 0.115)","(IL10RA, 0.084)","(STAT5A, 0.002)","(STAT5B, -0.009)","(STAT1, -0.011)","(JAK3, -0.011)","(TYK2, -0.085)","(SOCS3, -0.096)","(STAT3, -0.12)","(JAK2, -0.251)"]
[1070,"actin filament severing (GO:0051014)",2,0.761,1,0.93161,"(VIL1, 0.02)","(GSN, -0.251)"]
[1070,"tgfbPathway BioCarta",14,0.761,1,1,"(SKIL, 0.42)","(TGFBR2, 0.42)","(EP300, 0.045)","(MAPK3, 0.042)","(TGFBR1, 0.036)","(MAP3K7IP1, 0.014)","(TGFB3, 0.006)","(MAP2K1, -0.027)","(MAP3K7, -0.033)","(TGFB2, -0.048)","(CREBBP, -0.097)","(TGFB1, -0.127)","(APC, -0.141)","(CDH1, -0.153)"]
[1072,"glutamate signaling pathway (GO:0007215)",10,0.762,1,0.57471,"(GRIN2C, 0.251)","(GRIN2B, 0.251)","(GRIA3, 0.169)","(GRIN2A, 0.132)","(GRIK1, 0.053)","(GRIA4, -0.049)","(GRIK2, -0.055)","(GRID2, -0.113)","(GRIK3, -0.174)","(GRIK4, -0.177)"]
[1072,"dopamine receptor signaling pathway (GO:0007212)",3,0.762,1,0.93116,"(DRD1IP, 0.311)","(DRD3, -0.124)","(DRD4, -0.232)"]
[1072,"muscarinic acetylcholine receptor, phospholipase C activating pathway (GO:0007207)",2,0.762,1,0.989,"(CHRM2, 0.194)","(GNA15, -0.363)"]
[1075,"ST MONOCYTE AD PATHWAY Signalling Transduction KE",27,0.764,1,0.88599,"(CAMP, 0.709)","(GAS, 0.472)","(RAC1, 0.25)","(DAG1, 0.188)","(KCNJ5, 0.144)","(ITPR1, 0.057)","(HTATIP, 0.048)","(BF, 0.039)","(ITPR3, 0.004)","(PITX2, 0.004)","(MAPK1, -0.017)","(RHO, -0.038)","(GNAQ, -0.038)","(DLG4, -0.038)","(APC, -0.041)","(ITPR2, -0.063)","(GNAI1, -0.08)","(CAV3, -0.084)","(RYR1, -0.093)","(KCNJ9, -0.097)","(ASAH1, -0.101)","(EPHB2, -0.114)","(PTX1, -0.123)","(AKT1, -0.127)","(KCNJ3, -0.129)","(ADRB1, -0.152)","(PTX3, -0.215)"]
[1075,"male gonad development (GO:0008584)",8,0.764,1,0.9973,"(LHCGR, 0.578)","(SRD5A2, 0.183)","(DMRT1, 0.012)","(NR5A1, -0.08)","(PRKACG, -0.097)","(NCOA4, -0.122)","(SOX15, -0.131)","(ANKRD7, -0.265)"]
[1077,"DNA DAMAGE SIGNALLING GO",94,0.765,1,0.9077,"(DKFZP566E144, 0.449)","(BIRC3, 0.289)","(PTPRCAP, 0.209)","(BCL6, 0.182)","(ATR, 0.16)","(ERCC1, 0.16)","(ERCC2, 0.124)","(TREX1, 0.124)","(PCNA, 0.12)","(DDB1, 0.116)","(GADD45G, 0.115)","(CKN1, 0.11)","(GADD45B, 0.104)","(MSH2, 0.095)","(H2AFZ, 0.092)","(BBC3, 0.09)","(BIRC2, 0.089)","(ATRX, 0.087)","(FOXO3A, 0.085)","(REV3L, 0.07)","(BAX, 0.063)","(MLH1, 0.049)","(PMS2, 0.04)","(BAK1, 0.039)","(CHEK1, 0.027)","(REPRIMO, 0.021)","(TERT, 0.019)","(CDC25B, 0.014)","(HUS1, 0)","(GTSE1, 0)","(FEN1, 0)","(ERCC5, 0)","(BTG2, 0)","(XPA, 0)","(APEX1, 0)","(RAD9A, 0)","(RAD23A, 0)","(LGMN, 0)","(BRCA1, 0)","(TNFRSF10B, 0)","(UNG, 0)","(TNF, 0)","(CDC6, 0)","(PRKDC, 0)","(RAD52, 0)","(CDC25A, 0)","(XPC, 0)","(LIG4, 0)","(TNFSF4, 0)","(ERCC4, 0)","(MDM2, 0)","(PIN1, 0)","(RAD1, 0)","(ERCC3, 0)","(CHEK2, 0)","(TNFRSF6, 0)","(RAD51, 0)","(XRCC2, 0)","(ATM, 0)","(XRCC1, 0)","(RPL13A, 0)","(H2AFY, 0)","(BNIP3, 0)","(CDC25C, 0)","(BRCA2, 0)","(RAD17, 0)","(MSH3, 0)","(LRDD, 0)","(GADD45A, 0)","(WEE1, 0)","(ARTN, 0)","(CDS1, 0)","(CDC20, 0)","(XRCC4, 0)","(MSH6, 0)","(XRCC5, 0)","(MRE11A, 0)","(MPG, 0)","(RAD50, 0)","(RAD23B, 0)","(GAPD, 0)","(TNFRSF4, 0)","(SESN1, 0)","(CDK4, 0)","(CDKN1A, 0)","(PPM1D, 0)","(DDB2, 0)","(ACTB, 0)","(SRPX, -0.008)","(TP53, -0.008)","(PURA, -0.01)","(CDKN2D, -0.01)","(APAF1, -0.032)","(PPIA, -0.082)"]
[1077,"transmembrane receptor protein tyrosine phosphatase signaling pathway (GO:0007185)",6,0.765,1,0.93271,"(PTPRD, 0.229)","(PTPRU, 0.22)","(PTN, 0.03)","(PTPRF, -0.079)","(TRIO, -0.126)","(PTPRS, -0.277)"]
[1077,"eye pigment biosynthesis (GO:0006726)",4,0.765,1,0.99052,"(GPR143, 0.352)","(OCA2, 0.098)","(AP3D1, -0.219)","(TYR, -0.254)"]
[1080,"protein-lipoylation (GO:0009249)",3,0.766,1,0.952,"(NNAT, 0.114)","(NMT1, -0.069)","(NMT2, -0.162)"]
[1080,"ecmPathway Extracellular matrix induces integrin-mediated FAK phosphorylation in epithelial cells, leading to PI3 and MAP kinase activation and actin reorganization.",22,0.766,1,0.9783,"(DIAPH1, 0.48)","(MYLK, 0.327)","(FYN, 0.233)","(ROCK1, 0.084)","(MAPK3, 0.073)","(RAF1, 0.055)","(PFN1, 0.004)","(ARHGAP5, -0.007)","(SRC, -0.019)","(MAPK1, -0.028)","(ITGB1, -0.044)","(SHC1, -0.058)","(HRAS, -0.068)","(PXN, -0.07)","(MAP2K1, -0.076)","(TLN1, -0.079)","(PIK3R1, -0.081)","(MYL2, -0.093)","(PTK2, -0.132)","(PIK3CA, -0.133)","(GSN, -0.136)","(ITGA1, -0.152)"]
[1080,"SA PROGRAMMED CELL DEATH SigmaAldrich",12,0.766,1,1,"(BCL10, 0.816)","(BAK1, 0.161)","(BCL2, 0.124)","(BAX, 0.123)","(BAD, 0.082)","(BCL2L11, -0.069)","(CASP9, -0.104)","(CASP8AP2, -0.128)","(APAF1, -0.136)","(CES1, -0.155)","(BID, -0.157)","(BCL2L1, -0.206)"]
[1083,"cdc25Pathway The protein phosphatase Cdc25 is phosphorylated by Chk1 and activates Cdc2 to stimulate eukaryotic cells into M phase.",9,0.767,1,0.88699,"(CHEK1, 0.229)","(CDC25B, 0.164)","(MYT1, 0.058)","(CDC25A, 0.047)","(WEE1, 0.033)","(ATM, -0.026)","(YWHAH, -0.063)","(CDC2, -0.078)","(CDC25C, -0.157)"]
[1083,"ureacyclePathway BioCarta",7,0.767,1,1,"(ASS, 0.204)","(GLS, 0.038)","(ASL, -0.037)","(GLUD1, -0.046)","(ARG1, -0.09)","(GOT1, -0.184)","(CPS1, -0.217)"]
[1085,"neuronal ion channel clustering (GO:0045161)",2,0.769,1,0.9457,"(PRKCABP, 0.198)","(NLGN1, -0.354)"]
[1086,"androgen receptor signaling pathway (GO:0030521)",10,0.77,1,0.95836,"(CRSP2, 0.403)","(PPAP2A, 0.271)","(THRAP5, 0.18)","(THRAP1, -0.041)","(THRAP4, -0.045)","(DAXX, -0.073)","(CRSP6, -0.1)","(THRAP3, -0.107)","(PPARBP, -0.147)","(ARID1A, -0.227)"]
[1087,"nos1Pathway BioCarta",22,0.771,1,0.91795,"(PRKAR2A, 0.243)","(PRKACB, 0.222)","(PRKAR1B, 0.152)","(GRIN2B, 0.141)","(PPP3CC, 0.139)","(GRIN2C, 0.11)","(PRKAR2B, 0.094)","(GRIN2A, 0.066)","(GRIN2D, 0.043)","(PPP3CA, 0)","(CALM1, -0.012)","(GRIN1, -0.016)","(PRKAR1A, -0.057)","(PRKACG, -0.065)","(CALM2, -0.065)","(SYT1, -0.076)","(PRKCB1, -0.09)","(NOS1, -0.095)","(DLG4, -0.1)","(PPP3CB, -0.177)","(CALM3, -0.185)","(PRKCA, -0.188)"]
[1087,"DNA damage response, signal transduction resulting in induction of apoptosis (GO:0008630)",6,0.771,1,0.93363,"(TP73, 0.146)","(TP53, 0.074)","(CIDEA, 0.071)","(ABL1, -0.072)","(CIDEB, -0.107)","(PDCD8, -0.264)"]
[1087,"MAP00740 Riboflavin metabolism BLACK",5,0.771,1,1,"(ACP5, 0.315)","(ACPP, -0.003)","(ACP2, -0.15)","(ACP1, -0.231)","(TYR, -0.253)"]
[1090,"caspase activation via cytochrome c (GO:0008635)",5,0.772,1,0.7717,"(CYCS, 0.174)","(DIABLO, 0.05)","(TP53, -0.024)","(APAF1, -0.121)","(CASP9, -0.234)"]
[1090,"atrbrcaPathway BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility.",21,0.772,1,1,"(FANCA, 0.257)","(FANCF, 0.244)","(TREX1, 0.225)","(ATR, 0.202)","(BRCA1, 0.167)","(CHEK1, 0.147)","(RAD50, 0.086)","(FANCE, 0.077)","(NBS1, 0.034)","(TP53, 0.028)","(FANCG, 0.022)","(CHEK2, -0.028)","(BRCA2, -0.033)","(ATM, -0.045)","(FANCC, -0.057)","(RAD9A, -0.075)","(RAD1, -0.079)","(HUS1, -0.08)","(RAD17, -0.083)","(MRE11A, -0.159)","(RAD51, -0.159)"]
[1092,"intracellular signaling cascade (GO:0007242)",32,0.773,1,0.9181,"(DFFB, 0.436)","(TYROBP, 0.364)","(BTK, 0.315)","(HCLS1, 0.235)","(PRKAR2A, 0.17)","(GMIP, 0.132)","(AKAP7, 0.121)","(PRKAR2B, 0.113)","(TLK1, 0.091)","(TESK2, 0.089)","(TREM1, 0.086)","(JAK1, 0.06)","(SPHK1, 0.057)","(PIP5K3, 0.053)","(STMN1, 0.032)","(EFS, 0.016)","(PRKAR1A, 0.001)","(CRKL, 0)","(CARHSP1, 0)","(APS, 0)","(TLK2, -0.013)","(SIRPB2, -0.026)","(ANP32A, -0.037)","(IL8, -0.086)","(LAT, -0.09)","(FKBP8, -0.091)","(DGKA, -0.107)","(LCK, -0.112)","(CORO2A, -0.119)","(DFFA, -0.126)","(FER, -0.16)","(JAK2, -0.2)"]
[1092,"response to radiation (GO:0009314)",4,0.773,1,0.95831,"(PPM1D, 0.087)","(PNKP, 0.037)","(CCL11, -0.159)","(SMC1L1, -0.206)"]
[1094,"Cell Cycle The progression of biochemical and morphological events that occur during nuclear or cellular replication.",76,0.774,1,1,"(HDAC5, 0.362)","(BUB3, 0.337)","(MCM4, 0.204)","(PTTG1, 0.178)","(RB1, 0.175)","(CDKN1B, 0.169)","(CDC14A, 0.167)","(PTTG2, 0.16)","(CCNE1, 0.153)","(MAD2L1, 0.15)","(PCNA, 0.144)","(MCM7, 0.141)","(BUB1, 0.098)","(ITM1, 0.084)","(E2F1, 0.08)","(GSK3B, 0.077)","(CDC25B, 0.06)","(ORC3L, 0.047)","(CHEK1, 0.028)","(CCNB2, 0.008)","(ORC1L, 0.007)","(CCNH, 0.006)","(CCNA1, 0.003)","(CDK6, 0)","(HDAC4, 0)","(ESPL1, 0)","(HDAC2, 0)","(E2F3, 0)","(MCM6, 0)","(LOC51270, 0)","(PRKDC, 0)","(CDC6, 0)","(HDAC7A, 0)","(ABL1, 0)","(ORC5L, 0)","(CDC25A, 0)","(CDK2, 0)","(SMC1L1, 0)","(ORC6L, 0)","(E2F6, 0)","(BUB1B, 0)","(TP53, 0)","(CDKN2A, 0)","(PKMYT1, 0)","(CHEK2, 0)","(HDAC6, 0)","(CCNE2, 0)","(MCM2, 0)","(ORC4L, 0)","(TGFB1, 0)","(ORC2L, 0)","(CDC45L, 0)","(MCM3, 0)","(TFDP1, 0)","(E2F5, 0)","(CCND2, 0)","(CDC25C, 0)","(E2F4, 0)","(GADD45A, 0)","(WEE1, 0)","(HDAC1, 0)","(SKP2, 0)","(CDC20, 0)","(HDAC3, 0)","(MAD1L1, 0)","(CCNA2, 0)","(CDC7, 0)","(CDC2, 0)","(CDK4, 0)","(CCNB1, 0)","(CCND3, 0)","(CDKN1A, 0)","(E2F2, -0.015)","(MCM5, -0.016)","(MDM2, -0.032)","(ATM, -0.056)"]
[1095,"CR REPAIR PNAS 2011",41,0.775,1,1,"(XRCC3, 0.683)","(ERCC1, 0.198)","(CKN1, 0.194)","(MSH2, 0.19)","(DDB1, 0.184)","(MLH1, 0.157)","(PCNA, 0.139)","(FEN1, 0.126)","(ADPRT, 0.094)","(ERCC3, 0.081)","(FRAP1, 0.049)","(RAD23A, 0.048)","(BRCA1, 0.037)","(RAD50, 0.022)","(G22P1, 0.015)","(XPC, 0.007)","(PMS2, 0)","(PMS1, 0)","(CHEK2, 0)","(XPA, 0)","(RAD17, -0.008)","(XRCC5, -0.017)","(RAD54L, -0.02)","(ERCC5, -0.025)","(RAD51L1, -0.029)","(OGG1, -0.037)","(RAD51, -0.041)","(APEX1, -0.047)","(RAD9A, -0.055)","(RAD52, -0.064)","(ERCC4, -0.071)","(MSH6, -0.077)","(POLD1, -0.079)","(RAD1, -0.081)","(EXO1, -0.085)","(DDB2, -0.089)","(MSH3, -0.106)","(ALKBH, -0.107)","(BRCA2, -0.11)","(PIR51, -0.148)","(RAD23B, -0.155)"]
[1096,"UPREG BY HOXA9 Manually Curated",34,0.776,1,0.85858,"(MAFG, 0.591)","(OSBPL9, 0.35)","(PIM1, 0.196)","(GNG10, 0.168)","(PCMT1, 0.166)","(ARPC5, 0.144)","(ARL3, 0.124)","(INPPL1, 0.103)","(ETS2, 0.072)","(PKNOX1, 0.06)","(GTPBP1, 0.028)","(VIM, 0.023)","(HNRPU, 0.007)","(CALB1, 0)","(YES1, -0.046)","(ALDH1A1, -0.053)","(PHOX2A, -0.066)","(TDE2, -0.068)","(ADD3, -0.07)","(SFRS11, -0.072)","(ARHGAP11A, -0.081)","(CDK7, -0.082)","(HMGN2, -0.083)","(RAB31, -0.083)","(ST13, -0.087)","(RNF103, -0.088)","(MYB, -0.095)","(RPL27A, -0.095)","(DHX8, -0.114)","(MAN2A2, -0.123)","(NLK, -0.13)","(RAP1B, -0.133)","(CUGBP1, -0.184)","(CTH, -0.185)"]
[1097,"response to nutrient (GO:0007584)",14,0.777,1,0.55899,"(ENSA, 0.455)","(STC2, 0.199)","(OGT, 0.099)","(PPARG, 0.08)","(BRS3, 0.068)","(GCGR, 0.045)","(SSTR1, -0.03)","(ENPP1, -0.066)","(SSTR2, -0.086)","(GNAI2, -0.091)","(STC1, -0.094)","(GIPR, -0.12)","(CCKAR, -0.135)","(TULP4, -0.164)"]
[1097,"negative regulation of translation (GO:0016478)",2,0.777,1,0.80353,"(IREB2, 0.227)","(ACO1, -0.45)"]
[1097,"RNA splicing (GO:0008380)",42,0.777,1,0.82642,"(SF3B4, 0.342)","(SF3A3, 0.292)","(SNRPG, 0.289)","(LSM1, 0.217)","(PPP2R1B, 0.211)","(SIP1, 0.204)","(SMNDC1, 0.133)","(NONO, 0.13)","(SF3A2, 0.126)","(KHSRP, 0.122)","(SFRS2, 0.119)","(PRPF18, 0.113)","(PTBP1, 0.106)","(DHX16, 0.1)","(NOVA1, 0.092)","(SYNCRIP, 0.072)","(U2AF1, 0.044)","(NOL3, 0.023)","(LSM4, 0.023)","(PPARGC1A, 0.018)","(SNRPB, 0.007)","(SFRS11, 0.007)","(SNRP70, 0)","(SF3A1, 0)","(SNRPB2, 0)","(SF3B2, 0)","(PRPF4B, -0.007)","(PPIG, -0.008)","(SNRPA1, -0.009)","(SF3B3, -0.016)","(U2AF1L2, -0.016)","(SFRS4, -0.017)","(SFPQ, -0.023)","(PPAN, -0.029)","(PRPF3, -0.058)","(CDC40, -0.073)","(HNRPC, -0.098)","(SNRPC, -0.104)","(DHX8, -0.104)","(SFRS7, -0.117)","(NCBP1, -0.127)","(HNRPH3, -0.155)"]
[1100,"G-protein signaling, coupled to cyclic nucleotide second messenger (GO:0007187)",37,0.778,1,0.76056,"(HRH2, 0.351)","(LHCGR, 0.233)","(HTR1F, 0.228)","(XCR1, 0.171)","(CCR1, 0.169)","(SSTR3, 0.162)","(HTR4, 0.154)","(CNR2, 0.109)","(HTR1E, 0.1)","(SSTR5, 0.099)","(EDG7, 0.092)","(NPY, 0.075)","(HTR1D, 0.06)","(DRD1, 0.059)","(MTNR1B, 0.033)","(MC1R, 0.031)","(NPY1R, 0.014)","(OPRD1, 0.006)","(CNR1, 0.005)","(TSHR, 0.002)","(MC2R, 0)","(MC3R, -0.012)","(SSTR1, -0.012)","(CCL2, -0.029)","(HTR7, -0.041)","(HRH3, -0.042)","(HTR1B, -0.05)","(SSTR2, -0.066)","(OPRM1, -0.068)","(MC5R, -0.085)","(MTNR1A, -0.12)","(HTR6, -0.12)","(VIPR1, -0.122)","(PTHR1, -0.145)","(CALCRL, -0.16)","(PTGIR, -0.181)","(SSTR4, -0.213)"]
[1100,"positive regulation of interleukin-6 biosynthesis (GO:0045410)",3,0.778,1,0.9117,"(TLR4, 0.352)","(TLR1, -0.177)","(TLR6, -0.319)"]
[1100,"hdacPathway BioCarta",29,0.778,1,1,"(HDAC5, 0.49)","(NFATC1, 0.322)","(MAPK14, 0.225)","(CAMK1G, 0.199)","(IGF1, 0.179)","(MAPK7, 0.165)","(PPP3CC, 0.13)","(AVP, 0.024)","(YWHAH, 0.01)","(CALM2, -0.004)","(MEF2B, -0.006)","(PIK3R1, -0.01)","(PPP3CA, -0.012)","(CALM1, -0.014)","(INS, -0.015)","(MEF2D, -0.028)","(MAP2K6, -0.031)","(CAMK1, -0.041)","(IGF1R, -0.05)","(MYOD1, -0.091)","(SYT1, -0.092)","(PIK3CA, -0.093)","(INSR, -0.097)","(CABIN1, -0.112)","(CALM3, -0.117)","(MEF2C, -0.123)","(AKT1, -0.139)","(PPP3CB, -0.146)","(MEF2A, -0.152)"]
[1103,"organic anion transport (GO:0015711)",3,0.779,1,1,"(SLCO1B1, 0.002)","(SLCO1A2, -0.036)","(SLCO1B3, -0.301)"]
[1104,"sensory perception of taste (GO:0050909)",3,0.781,1,0.98896,"(TAS2R3, 0.166)","(TAS2R4, -0.061)","(TAS2R16, -0.317)"]
[1105,"acetylcholine receptor signaling, muscarinic pathway (GO:0007213)",3,0.783,1,0.93409,"(CHRM5, 0.027)","(CHRM4, -0.035)","(AGRN, -0.045)"]
[1105,"TESTIS GENES FROM XHX AND NETAFFX na",72,0.783,1,1,"(TCTE1L, 0.344)","(SLC6A8, 0.321)","(EIF1AY, 0.285)","(HSD17B3, 0.239)","(TCTEL1, 0.234)","(SCML1, 0.228)","(CYLC2, 0.213)","(ISYNA1, 0.209)","(DDX4, 0.203)","(ADAM2, 0.196)","(SOX5, 0.134)","(ACE2, 0.095)","(CLGN, 0.087)","(WDR10, 0.076)","(DDX43, 0.075)","(TEX15, 0.068)","(DNAJC4, 0.042)","(PPP2R1B, 0.038)","(TSGA10, 0.032)","(TSC, 0.014)","(CHODL, 0.009)","(MCSP, 0)","(HLC-8, 0)","(ADAM29, 0)","(DNALI1, 0)","(FAM12B, 0)","(GRB14, 0)","(PRM2, 0)","(PTGDS, 0)","(USP2, 0)","(PSORS1C1, 0)","(TEX13A, 0)","(DDX3X, 0)","(AMH, 0)","(NUP98, 0)","(SOX30, 0)","(TEX14, 0)","(DKFZP434P211, 0)","(DKFZp434H2215, 0)","(BGR, 0)","(DMRT1, 0)","(STK22B, 0)","(GPR135, 0)","(SPINLW1, 0)","(FLJ36166, 0)","(SSX2IP, 0)","(TTTY15, 0)","(ALG8, 0)","(CTAG2, 0)","(HSPA1L, 0)","(CRAT, 0)","(KCTD13, 0)","(TZFP, 0)","(GAPDS, -0.007)","(COIL, -0.008)","(CRISP1, -0.011)","(TF, -0.014)","(RNASE1, -0.015)","(WT1, -0.017)","(SPACA1, -0.021)","(BRDT, -0.028)","(TFDP2, -0.03)","(TSKS, -0.037)","(NR0B1, -0.073)","(CXADR, -0.083)","(TCP11, -0.113)","(MNS1, -0.119)","(MAP7, -0.13)","(BAT2, -0.134)","(POMZP3, -0.143)","(DDX3Y, -0.159)","(TTTY2, -0.2)"]
[1107,"MAP kinase kinase activity GenMAPP",8,0.786,1,0.92453,"(MAPK14, 0.424)","(MAPKAPK3, 0.26)","(MAPKAPK5, 0.041)","(MAP2K7, -0.071)","(MAP2K3, -0.097)","(MAP2K1, -0.134)","(MAPK10, -0.155)","(MAP2K6, -0.218)"]
[1107,"neuromuscular synaptic transmission (GO:0007274)",2,0.786,1,0.93556,"(KIF1B, 0.015)","(DTNA, -0.466)"]
[1107,"dicarboxylic acid transport (GO:0006835)",2,0.786,1,1,"(SLC25A10, 0.011)","(SLC1A7, -0.378)"]
[1110,"par1Pathway BioCarta",20,0.788,1,0.59251,"(PTK2B, 0.547)","(F2RL3, 0.403)","(ADCY1, 0.123)","(GNB1, 0.103)","(ROCK1, 0.097)","(GNA12, 0.072)","(ARHGEF1, 0.059)","(F2, 0.038)","(GNAI1, 0.018)","(PIK3R1, -0.031)","(GNAQ, -0.049)","(MAP3K7, -0.074)","(F2R, -0.081)","(PRKCB1, -0.081)","(PPP1R12B, -0.083)","(PIK3CA, -0.1)","(GNA13, -0.102)","(PLCB1, -0.108)","(PRKCA, -0.153)","(GNGT1, -0.218)"]
[1111,"parturition (GO:0007567)",5,0.789,1,0.93717,"(PTGFR, 0.199)","(MAFF, 0.123)","(OXT, 0.096)","(CRHR1, -0.105)","(CRH, -0.3)"]
[1111,"regulation of translational termination (GO:0006449)",2,0.789,1,0.98969,"(RENT1, 0.124)","(MTRF1, -0.474)"]
[1111,"ST ADRENERGIC Signalling Transduction KE",37,0.789,1,0.99093,"(CAMP, 0.645)","(GAS, 0.444)","(MAPK14, 0.157)","(KCNJ5, 0.128)","(DAG1, 0.125)","(ITPR1, 0.076)","(RAF1, 0.067)","(PHKA2, 0.063)","(CCL15, 0.056)","(BRAF, 0.04)","(BF, 0.034)","(CCL16, 0.021)","(EGFR, 0.013)","(AR, 0.011)","(ITPKA, -0.007)","(MAPK1, -0.012)","(ITPR2, -0.015)","(SRC, -0.021)","(APC, -0.035)","(GNA11, -0.065)","(ITPR3, -0.067)","(GNA15, -0.071)","(PIK3R1, -0.077)","(PTX1, -0.078)","(PITX2, -0.079)","(PIK3CA, -0.08)","(KCNJ9, -0.084)","(GNAQ, -0.084)","(CCL13, -0.09)","(GNAI1, -0.091)","(ASAH1, -0.093)","(ITPKB, -0.113)","(AKT1, -0.124)","(KCNJ3, -0.128)","(MAPK10, -0.129)","(PIK3CD, -0.14)","(PTX3, -0.159)"]
[1114,"il7Pathway BioCarta",16,0.79,1,0.68817,"(PTK2B, 0.582)","(FYN, 0.229)","(IL7R, 0.167)","(BCL2, 0.104)","(STAT5A, 0.016)","(STAT5B, 0.006)","(JAK3, -0.004)","(JAK1, -0.012)","(EP300, -0.016)","(IL7, -0.03)","(PIK3R1, -0.038)","(CREBBP, -0.055)","(PIK3CA, -0.074)","(LCK, -0.131)","(NMI, -0.136)","(IL2RG, -0.165)"]
[1114,"snRNA transcription (GO:0009301)",2,0.79,1,0.84649,"(SNAPC2, 0.063)","(SNAPC3, -0.385)"]
[1114,"triacylglycerol metabolism (GO:0006641)",5,0.79,1,1,"(DGAT1, 0.161)","(PNLIP, 0.065)","(CEL, -0.035)","(ANGPTL3, -0.036)","(PNLIPRP2, -0.259)"]
[1117,"calcium ion transport (GO:0006816)",15,0.791,1,0.74933,"(SLC8A1, 0.435)","(TRPV5, 0.255)","(TRPM2, 0.16)","(NPY, 0.151)","(CCL8, 0.076)","(ATP2C1, 0.055)","(TRPC1, -0.015)","(CD7, -0.03)","(CSN2, -0.046)","(TRPC4, -0.052)","(TRPC3, -0.066)","(CACNA1I, -0.073)","(TRPC5, -0.13)","(RYR1, -0.154)","(RYR3, -0.179)"]
[1117,"oligosaccharide metabolism (GO:0009311)",4,0.791,1,1,"(ST6GAL1, 0)","(ST8SIA3, 0)","(ST8SIA4, 0)","(MAN1B1, -0.001)"]
[1119,"establishment and/or maintenance of chromatin architecture (GO:0006325)",6,0.792,1,0.90132,"(SATB1, 0.02)","(HMGA2, 0.004)","(EZH2, -0.015)","(SAFB, -0.044)","(BRCA2, -0.123)","(HMGB1, -0.123)"]
[1120,"shh lisa Manually Curated",18,0.793,1,0.82273,"(PRKACB, 0.248)","(PRKAR2A, 0.232)","(CDK8, 0.212)","(GSK3B, 0.158)","(DYRK2, 0.138)","(PRKAR2B, 0.097)","(XPO1, 0.065)","(GLI, 0.001)","(CDK2, -0.005)","(DYRK1A, -0.016)","(RASGRF1, -0.029)","(PTCH, -0.037)","(CCNB1, -0.052)","(GLI2, -0.058)","(GLIPR1, -0.081)","(FGF4, -0.11)","(PRKACG, -0.125)","(BMP2, -0.189)"]
[1120,"detection of abiotic stimulus (GO:0009582)",2,0.793,1,0.96621,"(TACR1, -0.138)","(TAC1, -0.348)"]
[1122,"smooth muscle contraction (GO:0006939)",10,0.794,1,0.73469,"(MLNR, 0.323)","(KCNMB2, 0.237)","(BRS3, 0.137)","(BDKRB2, 0.064)","(KNG1, -0.055)","(ADRA1A, -0.075)","(C3AR1, -0.11)","(SMTN, -0.155)","(KCNMB1, -0.189)","(CCKAR, -0.24)"]
[1122,"tob1Pathway BioCarta",18,0.794,1,1,"(TGFBR2, 0.372)","(CD3E, 0.304)","(TRA@, 0.206)","(CD28, 0.195)","(TGFB3, -0.002)","(TGFBR3, -0.014)","(TGFBR1, -0.024)","(TOB2, -0.026)","(IFNG, -0.05)","(CD3G, -0.05)","(IL2RA, -0.054)","(TGFB2, -0.093)","(IL4, -0.111)","(IL2, -0.114)","(TGFB1, -0.125)","(CD3D, -0.132)","(TOB1, -0.165)","(CD3Z, -0.184)"]
[1124,"SA G2 AND M PHASES SigmaAldrich",8,0.795,1,0.40923,"(CHEK1, 0.163)","(CDC25B, 0.124)","(WEE1, 0.054)","(CDC2, 0.006)","(CDC25A, -0.023)","(NEK1, -0.052)","(CDK7, -0.081)","(CDKN1A, -0.149)"]
[1124,"protein deglycosylation (GO:0006517)",2,0.795,1,0.91572,"(MAN2B1, 0.064)","(AGA, -0.253)"]
[1124,"ST Interferon gamma Pathway Signalling Transduction KE",9,0.795,1,1,"(IFNGR1, 0.351)","(PTPRU, 0.157)","(JAK1, 0.1)","(STAT1, 0.084)","(CISH, -0.023)","(REG1A, -0.086)","(IFNG, -0.118)","(PLA2G2A, -0.128)","(JAK2, -0.186)"]
[1124,"CR TRANSCRIPTION FACTORS PNAS 2013",70,0.795,1,1,"(GLI3, 0.509)","(MAFG, 0.385)","(RXRA, 0.32)","(JUN, 0.275)","(BCL6, 0.224)","(PBX1, 0.215)","(CHES1, 0.179)","(TCF7L2, 0.171)","(LITAF, 0.17)","(SPI1, 0.144)","(FOSL2, 0.129)","(FOS, 0.089)","(ETV3, 0.081)","(SRF, 0.076)","(FOXD1, 0.044)","(ATF1, 0.019)","(PML, 0.011)","(PPARA, 0)","(HKR3, 0)","(EGR3, 0)","(GLI, 0)","(FLI1, 0)","(NME1, 0)","(RELA, 0)","(WT1, 0)","(ETV1, 0)","(MYBL2, 0)","(IRF4, 0)","(EGR1, 0)","(MYBL1, 0)","(ZNFN1A1, 0)","(MYOD1, 0)","(ETS1, 0)","(MYC, 0)","(MYB, 0)","(STAT5B, 0)","(JUND, 0)","(CBFB, 0)","(STAT6, 0)","(DPF2, 0)","(MLLT7, 0)","(SMARCA4, 0)","(RELB, 0)","(MYCN, 0)","(STAT5A, 0)","(JUNB, 0)","(FOSB, 0)","(RUNX1, 0)","(ETV6, 0)","(LMO1, 0)","(CEBPA, 0)","(PBX2, 0)","(ETS2, 0)","(NFKB2, 0)","(FOXF1, 0)","(CBFA2T3, 0)","(TLX1, 0)","(REL, 0)","(MAF, -0.005)","(AHR, -0.015)","(FOXD2, -0.015)","(EHF, -0.03)","(GAS41, -0.032)","(TIEG, -0.044)","(CBFA2T1, -0.045)","(AATF, -0.067)","(STAT3, -0.093)","(PAX7, -0.116)","(GLI2, -0.146)","(FOSL1, -0.164)"]
[1128,"cell cycle arrest (GO:0007050)",40,0.796,1,0.72833,"(INHA, 0.357)","(CDKN2C, 0.295)","(CUL1, 0.218)","(GAS1, 0.209)","(GAS7, 0.174)","(APBB2, 0.139)","(CUL3, 0.133)","(CDKN1C, 0.132)","(CDKN3, 0.121)","(PA2G4, 0.119)","(CDKN1B, 0.107)","(BTG4, 0.09)","(MYC, 0.079)","(SESN1, 0.054)","(EIF4G2, 0.03)","(ERN1, 0.019)","(RASSF1, 0.016)","(GADD45A, 0.005)","(CDKN1A, 0)","(MLLT7, -0.001)","(AIF1, -0.014)","(IL8, -0.021)","(CUL2, -0.032)","(MAPK12, -0.038)","(INHBA, -0.045)","(APBB1, -0.046)","(ING4, -0.049)","(IFNW1, -0.07)","(CDKN2D, -0.08)","(CUL5, -0.089)","(CDKN2A, -0.094)","(PPM1G, -0.107)","(TP53, -0.109)","(NOTCH2, -0.121)","(PCAF, -0.122)","(PLAGL1, -0.123)","(KHDRBS1, -0.127)","(CUL4A, -0.157)","(CDKN2B, -0.182)","(MAP2K6, -0.2)"]
[1129,"tRNA Synthetases BioCarta",19,0.797,1,0.37978,"(TARS, 0.455)","(YARS, 0.185)","(RARS, 0.158)","(IARS, 0.153)","(CARS, 0.152)","(DARS, 0.075)","(NARS, 0.074)","(QARS, 0)","(LARS, -0.033)","(EPRS, -0.035)","(SARS, -0.041)","(KARS, -0.048)","(MARS, -0.066)","(VARS2, -0.076)","(GARS, -0.082)","(HARS, -0.108)","(WARS, -0.138)","(HARSL, -0.151)","(AARS, -0.155)"]
[1129,"metPathway BioCarta",35,0.797,1,0.90805,"(CRK, 0.476)","(MET, 0.426)","(PTK2B, 0.421)","(JUN, 0.349)","(GAB1, 0.215)","(FOS, 0.142)","(ACTA1, 0.134)","(MAPK3, 0.087)","(RAF1, 0.049)","(MAPK1, 0.012)","(MAPK8, 0.006)","(PXN, -0.005)","(CRKL, -0.005)","(PIK3R1, -0.007)","(PTK2, -0.014)","(MAP2K2, -0.018)","(ELK1, -0.019)","(SOS1, -0.027)","(GRB2, -0.032)","(HRAS, -0.047)","(PTPN11, -0.056)","(MAP4K1, -0.064)","(ITGB1, -0.073)","(MAP2K1, -0.075)","(SRC, -0.077)","(STAT3, -0.084)","(PIK3CA, -0.09)","(RAP1B, -0.098)","(PTEN, -0.1)","(PAK1, -0.103)","(HGF, -0.121)","(DOCK1, -0.124)","(RASA1, -0.141)","(RAP1A, -0.186)","(ITGA1, -0.204)"]
[1131,"MAP00970 Aminoacyl tRNA biosynthesis GenMAPP",19,0.798,1,0.59268,"(TARS, 0.419)","(CARS, 0.213)","(RARS, 0.151)","(IARS, 0.103)","(NARS, 0.082)","(GARS, 0.033)","(DARS, 0.023)","(QARS, -0.002)","(WARS2, -0.008)","(KARS, -0.028)","(MARS, -0.033)","(EPRS, -0.042)","(WARS, -0.051)","(KIAA0335, -0.066)","(HARS, -0.098)","(HBG2, -0.109)","(SARS, -0.121)","(AARS, -0.121)","(HARSL, -0.13)"]
[1132,"transcription initiation from RNA polymerase II promoter (GO:0006367)",23,0.799,1,0.78471,"(GTF2E2, 0.282)","(CRSP2, 0.272)","(NCOA6, 0.2)","(THRAP5, 0.136)","(CRSP9, 0.124)","(GTF2E1, 0.109)","(PPARGC1A, 0.094)","(IRF7, 0.028)","(CDK7, 0.023)","(TBP, 0.018)","(E2F3, 0)","(THRAP3, -0.01)","(E2F2, -0.031)","(GTF2F1, -0.036)","(CRSP3, -0.046)","(PPARBP, -0.058)","(THRAP1, -0.079)","(CRSP6, -0.093)","(GTF2I, -0.101)","(CDK9, -0.113)","(THRAP4, -0.117)","(GTF2F2, -0.144)","(MAZ, -0.147)"]
[1132,"protein transport (GO:0015031)",3,0.799,1,0.87585,"(LMAN2L, -0.04)","(LRP1B, -0.116)","(CD3G, -0.139)"]
[1132,"regulation of transcription from RNA polymerase II promoter (GO:0006357)",139,0.799,1,0.89935,"(ZNF76, 0.387)","(SMARCD3, 0.286)","(RNF14, 0.272)","(FOXO1A, 0.234)","(CRK, 0.224)","(TCF1, 0.186)","(TFAP2C, 0.18)","(TADA3L, 0.164)","(SREBF1, 0.157)","(TCF4, 0.108)","(GCN5L2, 0.096)","(SURB7, 0.094)","(ASCL1, 0.088)","(KLF12, 0.079)","(POU2F3, 0.075)","(CRSP2, 0.072)","(TCEA1, 0.065)","(LITAF, 0.053)","(FOSL2, 0.05)","(SOX9, 0.036)","(SRF, 0.019)","(TFAP2A, 0.017)","(SREBF2, 0.016)","(HMGB2, 0)","(TEAD4, 0)","(POU4F1, 0)","(SOD2, 0)","(KLF7, 0)","(C19orf2, 0)","(SMARCA2, 0)","(ZNF143, 0)","(STAT6, 0)","(MYF5, 0)","(ATF6, 0)","(ID1, 0)","(NFE2, 0)","(TBX1, 0)","(PRKAR1A, 0)","(SOX10, 0)","(FOXF1, 0)","(DEK, 0)","(TIAL1, 0)","(NFYC, 0)","(TCEB3, 0)","(OIP106, 0)","(TAF6L, 0)","(SOX30, 0)","(CHD1, 0)","(SMARCA4, 0)","(JUND, 0)","(ATF5, 0)","(CRSP9, 0)","(ZNF354A, 0)","(TCF7L2, 0)","(SOX12, 0)","(TBX10, 0)","(HMGB1, 0)","(NR2F2, 0)","(SAP18, 0)","(NRF1, 0)","(SMARCC1, 0)","(SMARCE1, 0)","(CLOCK, 0)","(GATA1, 0)","(SOX18, 0)","(SPIB, 0)","(ID4, 0)","(TCF12, 0)","(HLXB9, 0)","(ZNF161, 0)","(CHD3, 0)","(RUVBL1, 0)","(FOXK2, 0)","(STAT5B, 0)","(YY1, 0)","(TARBP2, 0)","(STAT5A, 0)","(TFDP2, 0)","(JUNB, 0)","(BRD8, 0)","(NEUROD2, 0)","(HOXC6, 0)","(CITED2, 0)","(RNF4, 0)","(HNF4A, 0)","(NFATC3, 0)","(SOX15, 0)","(TCF7, 0)","(STAT4, 0)","(SP2, 0)","(SMARCB1, 0)","(HNF4G, 0)","(SUPT3H, 0)","(BLZF1, 0)","(SMARCD2, 0)","(CHD4, 0)","(G10, 0)","(TCEB1, 0)","(TBX19, 0)","(PPARG, 0)","(FOXN1, 0)","(MYC, 0)","(BRCA1, 0)","(NEUROG1, 0)","(SMARCD1, 0)","(MYCN, 0)","(SP4, 0)","(SMARCA5, 0)","(SOX21, 0)","(TEAD3, 0)","(DBP, 0)","(MED6, 0)","(GABPB2, 0)","(SMARCC2, 0)","(HIRA, 0)","(ELK3, 0)"]
[1135,"response to virus (GO:0009615)",28,0.8,1,0.89308,"(MGC10471, 0.314)","(CCL22, 0.223)","(HBXIP, 0.183)","(CXCL12, 0.183)","(OAS1, 0.179)","(CCL4, 0.175)","(IFNGR1, 0.138)","(LILRB1, 0.114)","(FGR, 0.082)","(IFNA4, 0.066)","(IFNGR2, 0.054)","(CCL8, 0.021)","(TNF, 0.018)","(TRIM22, 0.008)","(ISG20, 0.005)","(C19orf2, -0.007)","(IFNAR1, -0.008)","(BANF1, -0.023)","(ZF, -0.037)","(IFNA10, -0.047)","(IFNW1, -0.055)","(IFNAR2, -0.066)","(FOSL1, -0.067)","(IRF7, -0.072)","(CCL5, -0.074)","(CCL11, -0.085)","(CCL19, -0.09)","(EIF2B3, -0.126)"]
[1135,"positive regulation of lipid metabolism (GO:0045834)",2,0.8,1,0.96406,"(ANGPTL3, -0.061)","(ANGPTL4, -0.367)"]
[1135,"synaptic vesicle endocytosis (GO:0048488)",2,0.8,1,1,"(SYNJ1, -0.107)","(ITSN1, -0.311)"]
[1138,"response to xenobiotic stimulus (GO:0009410)",2,0.801,1,0.97541,"(AHR, -0.033)","(ARNT2, -0.434)"]
[1139,"nucleosome assembly (GO:0006334)",12,0.802,1,0.83089,"(HIST1H2BD, 0.188)","(SMARCA5, 0.178)","(NAP1L2, 0.091)","(NAP1L3, 0.071)","(NAP1L1, 0.064)","(NAP1L4, 0.003)","(HIST2H2BE, -0.016)","(HIST1H2BK, -0.09)","(SET, -0.115)","(HBXAP, -0.12)","(H3F3B, -0.196)","(HIST1H2BN, -0.199)"]
[1139,"pdgfPathway BioCarta",27,0.802,1,0.97815,"(PLCG1, 0.508)","(JUN, 0.387)","(SRF, 0.192)","(FOS, 0.158)","(STAT1, 0.061)","(RAF1, 0.057)","(MAPK3, 0.053)","(PDGFA, 0.045)","(STAT5A, 0.021)","(PIK3R1, 0.004)","(GRB2, -0.001)","(JAK1, -0.002)","(PDGFRA, -0.02)","(MAPK8, -0.023)","(SOS1, -0.025)","(HRAS, -0.036)","(SHC1, -0.042)","(ELK1, -0.045)","(MAP2K4, -0.069)","(MAP2K1, -0.082)","(MAP3K1, -0.089)","(PRKCB1, -0.102)","(CSNK2A1, -0.104)","(PIK3CA, -0.113)","(PRKCA, -0.15)","(RASA1, -0.183)","(STAT3, -0.184)"]
[1139,"regulation of exocytosis (GO:0017157)",2,0.802,1,1,"(SEPT5, 0)","(SYT1, -0.002)"]
[1142,"ck1Pathway Caseine kinase 1 (CK1) and cdk5 phosphorylate DARPP32 in the dopamine signaling pathway.",16,0.803,1,0.61904,"(PPP2CA, 0.334)","(PRKACB, 0.271)","(PRKAR2A, 0.232)","(PRKAR2B, 0.149)","(PRKAR1B, 0.093)","(DRD1, 0.079)","(PPP3CA, 0.009)","(DRD2, -0.039)","(PRKACG, -0.041)","(PPP1CA, -0.072)","(PLCB1, -0.08)","(CDK5, -0.102)","(PRKAR1A, -0.118)","(GRM1, -0.14)","(CDK5R1, -0.197)","(CSNK1D, -0.199)"]
[1142,"protein folding (GO:0006457)",35,0.803,1,0.86217,"(MKKS, 0.416)","(DNAJC7, 0.24)","(CLPX, 0.166)","(TTC1, 0.14)","(FKBP5, 0.123)","(FKBP4, 0.066)","(TXNDC4, 0.056)","(LRPAP1, 0.045)","(FKBP6, 0.041)","(BAG5, 0.036)","(LMAN1, 0.015)","(CCT4, 0.013)","(ERO1LB, 0.007)","(CLN3, 0)","(C12orf8, 0)","(DNAJA1, 0)","(CCT6B, -0.002)","(BAG4, -0.015)","(APCS, -0.033)","(DNAJB2, -0.039)","(TSC2, -0.044)","(CCT6A, -0.046)","(ST13, -0.049)","(PPIA, -0.051)","(RUVBL2, -0.061)","(ATF6, -0.062)","(PIN4, -0.074)","(AHSA1, -0.079)","(FKBP9, -0.082)","(DNAJA3, -0.097)","(NFYC, -0.133)","(BAG2, -0.139)","(PPIH, -0.15)","(CCT3, -0.154)","(CCT7, -0.182)"]
[1142,"cell cycle checkpoint A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage.",26,0.803,1,0.89812,"(TIMP3, 0.246)","(MCM4, 0.217)","(MAD2L1, 0.208)","(RPA3, 0.17)","(MCM7, 0.149)","(RPA2, 0.148)","(CHEK1, 0.123)","(GAPD, 0.092)","(BRCA1, 0.086)","(RAD50, 0.07)","(LCMT2, 0.036)","(NBS1, 0.033)","(RPA1, 0.017)","(ABL1, 0.007)","(ATM, -0.016)","(RAD17, -0.024)","(HUS1, -0.025)","(CHEK2, -0.063)","(TP53, -0.064)","(MXD3, -0.081)","(MSH3, -0.084)","(RAD9A, -0.086)","(GADD45A, -0.097)","(MCM6, -0.102)","(MRE11A, -0.116)","(RAD51, -0.136)"]
[1145,"cell cycle arrest Any process by which progression through the cell cycle is halted during one of the normal phases (G1, S, G2, M).",34,0.804,1,0.89302,"(CDKN2C, 0.307)","(C10orf7, 0.29)","(GAS1, 0.26)","(GAS7, 0.243)","(CUL1, 0.225)","(PR48, 0.193)","(CDKN1B, 0.178)","(CDKN1C, 0.149)","(CDKN3, 0.119)","(CUL3, 0.111)","(REPRIMO, 0.04)","(SESN1, 0.035)","(RPP14, 0.016)","(MYC, 0)","(EIF4G2, 0)","(CUL5, -0.024)","(CDKN2A, -0.032)","(CDKN1A, -0.038)","(KHDRBS1, -0.052)","(IFNW1, -0.059)","(GMNN, -0.067)","(GADD45A, -0.074)","(CUL4A, -0.085)","(MLLT7, -0.086)","(PLAGL1, -0.087)","(PCAF, -0.095)","(CDKN2D, -0.098)","(AIF1, -0.129)","(MAP2K6, -0.131)","(PPM1G, -0.133)","(PPP1R15A, -0.15)","(CDKN2B, -0.162)","(MAPK12, -0.167)","(CUL2, -0.174)"]
[1146,"phosphorylation (GO:0016310)",3,0.805,1,0.99343,"(FRAP1, 0.183)","(TOLLIP, -0.192)","(PGK1, -0.269)"]
[1147,"small GTPase mediated signal transduction (GO:0007264)",14,0.807,1,0.72501,"(ARFIP2, 0.371)","(RAPGEF2, 0.261)","(RRAD, 0.205)","(SIAH2, 0.111)","(CHP, 0.098)","(ABR, 0.093)","(RASGRP3, 0.045)","(PDK1, -0.018)","(DOCK1, -0.044)","(PLD2, -0.046)","(VAV3, -0.055)","(RRP22, -0.109)","(RAB6C, -0.119)","(RGS19, -0.128)"]
[1147,"SA TRKA RECEPTOR SigmaAldrich",16,0.807,1,0.79391,"(AKT2, 0.741)","(MAP2K2, 0.14)","(NGFR, 0.132)","(NTRK1, 0.099)","(GRB2, 0.03)","(HRAS, 0.002)","(SOS1, -0.007)","(SHC1, -0.073)","(MAP2K1, -0.078)","(AKT3, -0.088)","(PIK3CA, -0.102)","(CDKN1A, -0.125)","(NGFB, -0.135)","(ELK1, -0.147)","(AKT1, -0.159)","(PIK3CD, -0.276)"]
[1147,"mRNA processing BioCarta",43,0.807,1,0.79526,"(SFRS8, 0.445)","(SF3B4, 0.367)","(SF3A3, 0.311)","(SFRS5, 0.286)","(LSM1, 0.277)","(SIP1, 0.215)","(DHX15, 0.193)","(KHSRP, 0.163)","(SMNDC1, 0.157)","(SFRS2, 0.147)","(PRPF18, 0.135)","(CPSF6, 0.1)","(HNRPR, 0.094)","(U2AF2, 0.064)","(CPSF5, 0.054)","(ELAVL4, 0.051)","(PTBP1, 0.049)","(SFRS9, 0.046)","(NONO, 0.022)","(SPOP, 0.02)","(SFPQ, 0)","(U2AF1, 0)","(HNRPA1, 0)","(SLBP, 0)","(SNRPB2, 0)","(SFRS11, -0.003)","(PRPF8, -0.006)","(SFRS2IP, -0.012)","(SFRS1, -0.012)","(LSM5, -0.016)","(SNRP70, -0.037)","(SFRS4, -0.038)","(USP39, -0.041)","(LSM3, -0.083)","(SF3A1, -0.085)","(SFRS7, -0.085)","(PRPF3, -0.086)","(SF3B3, -0.1)","(FUSIP1, -0.105)","(HNRPA0, -0.113)","(KHDRBS1, -0.133)","(SFRS10, -0.133)","(CUGBP1, -0.14)"]
[1150,"muscle development (GO:0007517)",46,0.809,1,0.5801,"(SGCE, 0.48)","(ACHE, 0.426)","(MYH3, 0.215)","(IGF1, 0.195)","(TAGLN, 0.187)","(CAPN3, 0.187)","(EVC, 0.133)","(ITGA7, 0.126)","(FHL3, 0.122)","(SIX1, 0.112)","(FCMD, 0.104)","(MRAS, 0.033)","(ITGB1BP2, 0.024)","(MBNL1, 0.018)","(LMNA, 0.015)","(POU6F1, 0.014)","(MTSS1, 0.008)","(MEF2B, 0)","(SGCD, 0)","(LAMA2, 0)","(MTM1, 0)","(UTRN, 0)","(CTF1, 0)","(TAZ, 0)","(TEAD4, -0.002)","(FGF2, -0.004)","(SGCG, -0.01)","(CAV3, -0.013)","(GATA6, -0.019)","(MUSK, -0.02)","(MEF2D, -0.021)","(EMD, -0.036)","(APEG1, -0.04)","(SRI, -0.042)","(MAPK12, -0.042)","(TCF12, -0.046)","(COL6A3, -0.051)","(EGR3, -0.067)","(SMTN, -0.068)","(MEF2A, -0.08)","(GDF8, -0.089)","(COL5A3, -0.128)","(SGCA, -0.132)","(MEF2C, -0.146)","(CXCL10, -0.149)","(SGCB, -0.198)"]
[1151,"peroxisome organization and biogenesis (GO:0007031)",8,0.811,1,0.84979,"(VPS4B, 0.403)","(PEX3, 0.07)","(PEX1, -0.045)","(PEX10, -0.092)","(PEX16, -0.093)","(PXMP3, -0.149)","(PEX6, -0.154)","(ABCD3, -0.186)"]
[1151,"cholesterol homeostasis (GO:0042632)",2,0.811,1,0.91008,"(ABCG1, -0.134)","(APOE, -0.28)"]
[1151,"thyroid hormone generation (GO:0006590)",3,0.811,1,1,"(TPO, 0.001)","(DIO2, -0.082)","(DIO1, -0.146)"]
[1154,"TCA Manually Curated",15,0.813,1,0.61903,"(IDH3A, 0.434)","(SDHB, 0.18)","(SUCLA2, 0.178)","(SDHC, 0.124)","(SDHA, 0.052)","(IDH3G, 0.003)","(SUCLG1, -0.037)","(OGDH, -0.086)","(CS, -0.087)","(SDHD, -0.091)","(IDH2, -0.093)","(MDH2, -0.102)","(ACO2, -0.113)","(IDH3B, -0.137)","(FH, -0.142)"]
[1155,"chemicalPathway DNA damage promotes Bid cleavage, which stimulates mitochondrial cytochrome c release and consequent caspase activation, resulting in apoptosis.",22,0.814,1,0.76316,"(CASP3, 0.364)","(BAX, 0.158)","(BAD, 0.098)","(ADPRT, 0.081)","(STAT1, 0.072)","(BCL2, 0.04)","(CASP6, 0.025)","(CYCS, -0.009)","(TP53, -0.016)","(PRKCB1, -0.019)","(CASP7, -0.024)","(PXN, -0.029)","(BID, -0.046)","(TLN1, -0.049)","(ATM, -0.064)","(APAF1, -0.065)","(EIF2S1, -0.072)","(CASP9, -0.11)","(BCL2L1, -0.124)","(PTK2, -0.126)","(PRKCA, -0.128)","(AKT1, -0.13)"]
[1155,"DNA strand elongation (GO:0006271)",2,0.814,1,0.91814,"(RFC4, 0.056)","(RFC3, -0.324)"]
[1155,"protein homooligomerization (GO:0051260)",4,0.814,1,0.92458,"(DGKD, 0.21)","(PRKCABP, 0.036)","(SYT1, -0.334)","(RAD51, -0.403)"]
[1158,"positive regulation of angiogenesis (GO:0045766)",5,0.815,1,1,"(BTG1, 0.168)","(SPHK1, 0.108)","(ANGPTL3, 0.001)","(RHOB, -0.049)","(ANGPTL4, -0.181)"]
[1159,"mRNA export from nucleus (GO:0006406)",8,0.816,1,0.99115,"(NUP160, 0.235)","(NUP107, 0.172)","(BAT1, 0.163)","(NXF3, 0.031)","(HRB, 0.005)","(RAE1, -0.129)","(DDX39, -0.143)","(NUP133, -0.237)"]
[1160,"detection of calcium ion (GO:0005513)",5,0.818,1,0.81639,"(KCNMB2, 0.323)","(CASR, -0.024)","(KCNMB4, -0.184)","(SYT1, -0.231)","(KCNMB3, -0.241)"]
[1160,"ucalpainPathway BioCarta",16,0.818,1,1,"(RAC1, 0.371)","(CAPNS1, 0.287)","(ACTA1, 0.275)","(ACTN3, 0.175)","(SRC, 0.028)","(CAPN1, 0.009)","(ITGB1, -0.037)","(ACTN1, -0.058)","(ITGB3, -0.062)","(ACTN2, -0.065)","(TLN1, -0.068)","(PXN, -0.068)","(VIL2, -0.088)","(PTK2, -0.109)","(SPTAN1, -0.173)","(ITGA1, -0.219)"]
[1160,"slrp2Pathway BLACK",4,0.818,1,1,"(TGFB3, 0.06)","(TGFBR1, -0.015)","(TGFB2, -0.122)","(TGFB1, -0.232)"]
[1163,"CR TRANSPORT PNAS 2014",6,0.819,1,1,"(ABCC4, 0.129)","(NUP98, 0.048)","(KPNB1, -0.061)","(NUP214, -0.17)","(TPR, -0.182)","(SLC14A1, -0.324)"]
[1164,"mitotic recombination (GO:0006312)",3,0.82,1,0.95473,"(RAD52, 0.044)","(RAD54B, -0.105)","(RAD51, -0.291)"]
[1164,"JNK cascade (GO:0007254)",16,0.82,1,1,"(ADORA2B, 0.496)","(MAP4K3, 0.258)","(GPS1, 0.085)","(TNIK, 0.014)","(MAPK8, -0.004)","(MAP3K12, -0.01)","(GPS2, -0.029)","(PAK1, -0.035)","(CRKL, -0.041)","(DUSP10, -0.076)","(MAP2K4, -0.111)","(MAPK9, -0.112)","(MAP3K4, -0.119)","(MAPK10, -0.134)","(MAP4K2, -0.134)","(DUSP9, -0.136)"]
[1166,"spliceosomal snRNP biogenesis (GO:0000387)",2,0.821,1,0.92847,"(GEMIN7, -0.13)","(GEMIN6, -0.262)"]
[1166,"sppaPathway BioCarta",22,0.821,1,0.99913,"(PLA2G4A, 0.642)","(F2RL3, 0.421)","(MAPK3, 0.083)","(RAF1, 0.06)","(SRC, 0.005)","(F2, 0.003)","(F2R, -0.011)","(GNB1, -0.021)","(ITGB1, -0.031)","(MAPK1, -0.035)","(GNAI1, -0.052)","(HRAS, -0.072)","(TBXAS1, -0.083)","(MAP2K1, -0.092)","(PRKCB1, -0.106)","(PLCB1, -0.119)","(PRKCA, -0.12)","(PTGS1, -0.123)","(PTK2, -0.132)","(SYK, -0.137)","(ITGA1, -0.185)","(GNGT1, -0.204)"]
[1166,"CR CANCER TESTIS PNAS 2003",11,0.821,1,1,"(TESK1, 0.299)","(BAGE, 0.259)","(MAGEA9, 0.216)","(SSX1, 0.032)","(MAGEA8, -0.013)","(SSX2, -0.047)","(MAGEA3, -0.072)","(MAGEA10, -0.091)","(MAGEE1, -0.119)","(GAGE1, -0.171)","(CTAG2, -0.21)"]
[1169,"slrpPathway BioCarta",6,0.824,1,0.91875,"(DSPG3, 0.217)","(BGN, 0.003)","(KERA, -0.005)","(DCN, -0.098)","(LUM, -0.109)","(FMOD, -0.229)"]
[1169,"egfPathway The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways.",27,0.824,1,0.98094,"(PLCG1, 0.465)","(JUN, 0.386)","(EGF, 0.246)","(SRF, 0.238)","(FOS, 0.077)","(RAF1, 0.066)","(GRB2, 0.058)","(EGFR, 0.032)","(MAPK3, 0.02)","(STAT5A, 0.015)","(STAT1, 0.013)","(PIK3R1, 0.01)","(JAK1, -0.003)","(MAP2K1, -0.019)","(MAP2K4, -0.023)","(MAPK8, -0.031)","(HRAS, -0.047)","(MAP3K1, -0.049)","(PRKCB1, -0.05)","(SOS1, -0.055)","(PIK3CA, -0.066)","(STAT3, -0.116)","(SHC1, -0.126)","(ELK1, -0.138)","(RASA1, -0.158)","(PRKCA, -0.159)","(CSNK2A1, -0.164)"]
[1171,"Krebs-TCA Cycle BioCarta",28,0.826,1,0.8145,"(PDHB, 0.359)","(IDH3A, 0.342)","(PDK4, 0.19)","(SDHB, 0.166)","(SDHC, 0.118)","(DLD, 0.062)","(MDH1, 0.057)","(PDK2, 0.045)","(PDHA2, 0.021)","(SDHA, 0.017)","(PPM2C, 0.009)","(IDH3G, 0.009)","(PDK1, 0.002)","(OGDH, 0.001)","(SUCLG1, 0)","(IDH2, -0.004)","(CS, -0.044)","(PDK3, -0.047)","(PC, -0.049)","(IDH3B, -0.054)","(ACO2, -0.057)","(SDHD, -0.11)","(DLAT, -0.11)","(MDH2, -0.112)","(DLST, -0.135)","(PDHA1, -0.138)","(PDHX, -0.152)","(FH, -0.163)"]
[1171,"synaptic vesicle targeting (GO:0016080)",2,0.826,1,0.98733,"(PCLO, -0.047)","(NLGN1, -0.374)"]
[1173,"G1/S transition of mitotic cell cycle (GO:0000082)",11,0.828,1,0.79618,"(CUL1, 0.351)","(CUL3, 0.339)","(PPP6C, 0.23)","(BCAT1, 0.051)","(SKP2, -0.043)","(CUL5, -0.05)","(GSPT1, -0.109)","(CDC7, -0.131)","(CUL4A, -0.139)","(CUL2, -0.167)","(CDK4, -0.206)"]
[1174,"at1rPathway Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway.",34,0.83,1,0.87393,"(PTK2B, 0.444)","(JUN, 0.334)","(ATF2, 0.316)","(RAC1, 0.245)","(AGTR1, 0.126)","(MAPK3, 0.082)","(CALM2, 0.058)","(RAF1, 0.057)","(PAK1, 0.031)","(SOS1, 0.012)","(MEF2B, 0.009)","(MEF2D, 0)","(AGT, 0)","(PTK2, 0)","(MAP2K2, 0)","(MAPK8, -0.003)","(SRC, -0.007)","(MEF2A, -0.008)","(EGFR, -0.028)","(SYT1, -0.03)","(MAPK1, -0.03)","(HRAS, -0.032)","(GRB2, -0.037)","(CALM1, -0.038)","(CALM3, -0.041)","(SHC1, -0.059)","(MAP2K1, -0.061)","(GNAQ, -0.079)","(PRKCB1, -0.087)","(PRKCA, -0.092)","(MEF2C, -0.095)","(MAP2K4, -0.115)","(MAP3K1, -0.118)","(ELK1, -0.19)"]
[1175,"mitrPathway BioCarta",9,0.831,1,0.99139,"(CAMK1G, 0.413)","(HDAC9, 0.367)","(YWHAH, 0.023)","(MEF2B, -0.023)","(CAMK1, -0.053)","(MEF2D, -0.117)","(MEF2C, -0.162)","(MEF2A, -0.189)","(MYOD1, -0.194)"]
[1176,"elevation of cytosolic calcium ion concentration (GO:0007204)",36,0.833,1,0.9375,"(F2RL1, 0.294)","(SAA1, 0.229)","(CYSLTR1, 0.175)","(P2RY4, 0.169)","(CCR6, 0.158)","(CCR1, 0.133)","(AGTR1, 0.129)","(XCR1, 0.12)","(AVPR1A, 0.097)","(DRD1, 0.083)","(OPRL1, 0.081)","(EDG7, 0.053)","(CCR8, 0.046)","(BDKRB2, 0.019)","(AVPR1B, 0.012)","(CCKBR, 0)","(CCR3, 0)","(EDG6, -0.01)","(C5R1, -0.012)","(GALR2, -0.015)","(CCR9, -0.018)","(BDKRB1, -0.018)","(CXCR3, -0.03)","(EDG4, -0.032)","(C3AR1, -0.033)","(CACNA1A, -0.037)","(CXCL13, -0.038)","(EDNRA, -0.041)","(CCR2, -0.049)","(CALCA, -0.06)","(GNA15, -0.061)","(CCR4, -0.062)","(CCR7, -0.075)","(CCKAR, -0.092)","(EDG2, -0.097)","(GPR24, -0.097)"]
[1177,"ST Jak STAT Pathway Signalling Transduction KE",9,0.834,1,0.98977,"(PIAS1, 0.257)","(PTPRU, 0.175)","(JAK1, 0.079)","(CISH, 0.015)","(JAK3, -0.014)","(REG1A, -0.048)","(PIAS3, -0.093)","(SOAT1, -0.099)","(JAK2, -0.272)"]
[1178,"microtubule nucleation (GO:0007020)",4,0.835,1,1,"(TUBGCP5, -0.038)","(CENPJ, -0.045)","(TUBG1, -0.072)","(TUBGCP2, -0.296)"]
[1179,"il2rbPathway BioCarta",37,0.837,1,0.88657,"(RPS6KB1, 0.556)","(E2F1, 0.223)","(FOS, 0.167)","(SOCS1, 0.16)","(TNFSF6, 0.088)","(IRS1, 0.083)","(BAD, 0.069)","(TNFRSF6, 0.067)","(RAF1, 0.052)","(IL2RA, 0.045)","(MYC, 0.042)","(STAT5A, 0.022)","(BCL2, 0.017)","(JAK1, 0.013)","(MAPK3, 0.012)","(PPIA, 0)","(CBL, 0)","(MAPK1, 0)","(CFLAR, -0.009)","(PTPN6, -0.015)","(STAT5B, -0.017)","(PIK3R1, -0.017)","(SOS1, -0.036)","(SHC1, -0.044)","(JAK3, -0.048)","(SOCS3, -0.052)","(IL2RB, -0.061)","(GRB2, -0.062)","(ZNFN1A3, -0.064)","(HRAS, -0.066)","(SYK, -0.073)","(CRKL, -0.092)","(AKT1, -0.101)","(PIK3CA, -0.112)","(IL2RG, -0.117)","(NMI, -0.126)","(BCL2L1, -0.134)"]
[1180,"aifPathway BLACK",4,0.838,1,0.75212,"(CYCS, 0.095)","(ADPRT, 0.095)","(BCL2L1, -0.282)","(PDCD8, -0.287)"]
[1181,"generation of precursor metabolites and energy (GO:0006091)",59,0.839,1,0.93139,"(NDUFA2, 0.351)","(CKMT2, 0.342)","(ATP5C1, 0.221)","(PHKB, 0.166)","(GLP1R, 0.153)","(UCP3, 0.124)","(UCP1, 0.121)","(GCGR, 0.121)","(PPARD, 0.112)","(PPARA, 0.107)","(CROT, 0.062)","(PHKA2, 0.048)","(NDUFA1, 0.046)","(ATPIF1, 0.045)","(GNPDA1, 0.041)","(GYS2, 0.037)","(CD38, 0.034)","(SLC25A3, 0.026)","(ATP5J, 0.026)","(AVP, 0.024)","(AVPR1A, 0.022)","(SLC25A4, 0)","(AQP7, 0)","(POMC, 0)","(ATP5B, 0)","(PPP1R2, 0)","(NDUFB2, 0)","(ADRB3, 0)","(GIPR, 0)","(NRF1, 0)","(IPF1, 0)","(INS, 0)","(PHKG1, 0)","(LIPE, 0)","(NDUFA10, 0)","(ACO2, 0)","(PPARG, 0)","(ATP5G3, 0)","(INSR, 0)","(GBE1, 0)","(HMGCL, 0)","(OGDH, 0)","(PHKA1, 0)","(PHKG2, 0)","(COX17, 0)","(DLST, 0)","(QPRT, -0.008)","(ECHS1, -0.011)","(APOM, -0.013)","(WFS1, -0.02)","(ECH1, -0.021)","(FECH, -0.023)","(ACAA1, -0.035)","(CEBPA, -0.07)","(GAA, -0.075)","(ENPP1, -0.092)","(EHHADH, -0.092)","(GPR24, -0.101)","(ASIP, -0.114)"]
[1181,"transcription, DNA-dependent (GO:0006351)",2,0.839,1,0.95082,"(PTGER3, -0.059)","(PPP3CB, -0.402)"]
[1181,"SA DAG1 SigmaAldrich",10,0.839,1,0.98666,"(PDE1A, 0.426)","(TRH, 0.268)","(ESR1, 0.098)","(ITPKA, 0.022)","(PLCB2, -0.037)","(VIP, -0.053)","(PLCB1, -0.126)","(PDE1B, -0.149)","(PRL, -0.168)","(ESR2, -0.22)"]
[1181,"behavior (GO:0007610)",14,0.839,1,1,"(CNR2, 0.344)","(ZIC1, 0.183)","(OPRK1, 0.076)","(CNR1, 0.046)","(AGTR2, 0.04)","(MAOA, 0.039)","(HD, -0.011)","(HTR1A, -0.015)","(C7orf16, -0.046)","(OPRM1, -0.056)","(ADRA2C, -0.067)","(DRD3, -0.141)","(HPRT1, -0.174)","(FOSB, -0.188)"]
[1185,"female gamete generation (GO:0007292)",12,0.84,1,0.81512,"(USP9X, 0.438)","(DMC1, 0.141)","(GDF9, 0.048)","(BCL2L10, 0.041)","(FSHB, -0.027)","(TOB2, -0.053)","(BMP15, -0.058)","(MAGOH, -0.102)","(FSHR, -0.128)","(PARN, -0.146)","(SPO11, -0.159)","(FSHPRH1, -0.178)"]
[1186,"transforming growth factor beta receptor signaling pathway (GO:0007179)",15,0.841,1,0.72039,"(GDF5, 0.298)","(SMAD1, 0.118)","(SMAD7, 0.106)","(GDF9, 0.095)","(BMPR1A, 0.086)","(ACVRL1, 0.037)","(TGFBR3, 0.031)","(LTBP2, -0.019)","(GDF15, -0.041)","(MAP3K7, -0.053)","(FNTA, -0.056)","(GDF8, -0.097)","(TGFB1, -0.114)","(GDF10, -0.116)","(SMAD3, -0.211)"]
[1186,"stat3Pathway BioCarta",8,0.841,1,0.77083,"(MAPK3, 0.139)","(JAK1, 0.095)","(FRAP1, 0.04)","(JAK3, 0.027)","(MAPK1, -0.039)","(TYK2, -0.065)","(STAT3, -0.132)","(JAK2, -0.207)"]
[1186,"steroid biosynthesis (GO:0006694)",4,0.841,1,0.91455,"(NR0B1, -0.011)","(SCP2, -0.02)","(CYP19A1, -0.122)","(FDXR, -0.254)"]
[1189,"tpoPathway BioCarta",23,0.847,1,1,"(PLCG1, 0.542)","(JUN, 0.439)","(FOS, 0.22)","(MAPK3, 0.089)","(STAT5A, 0.086)","(RAF1, 0.019)","(STAT5B, 0.018)","(GRB2, 0.017)","(PIK3R1, 0)","(SOS1, 0)","(HRAS, -0.012)","(STAT1, -0.016)","(MAP2K1, -0.035)","(PRKCB1, -0.067)","(SHC1, -0.067)","(MPL, -0.07)","(THPO, -0.08)","(CSNK2A1, -0.099)","(STAT3, -0.104)","(PIK3CA, -0.11)","(JAK2, -0.11)","(PRKCA, -0.143)","(RASA1, -0.15)"]
[1190,"GPCRs Class A Rhodopsin-like GO",139,0.848,1,0.84264,"(LTB4R, 0.311)","(NTSR2, 0.263)","(ADRA2A, 0.235)","(GPR35, 0.218)","(F2RL1, 0.218)","(ADORA2B, 0.213)","(PTGER2, 0.177)","(IL8RA, 0.17)","(CX3CR1, 0.158)","(ADORA2A, 0.154)","(LHCGR, 0.124)","(GPR105, 0.113)","(CCRL1, 0.078)","(CXCR4, 0.071)","(ADRA1B, 0.07)","(HTR2B, 0.064)","(CCR1, 0.046)","(ADRB2, 0.024)","(HTR1F, 0.013)","(OPRL1, 0.009)","(AVPR1B, 0)","(GALR1, 0)","(AVPR2, 0)","(DRD4, 0)","(GPR17, 0)","(ADRA2C, 0)","(OXTR, 0)","(CCR3, 0)","(NPY5R, 0)","(GPR50, 0)","(HTR2C, 0)","(CCR8, 0)","(TSHR, 0)","(DRD3, 0)","(OPN3, 0)","(PPYR1, 0)","(NMBR, 0)","(MC1R, 0)","(CCR9, 0)","(GALR2, 0)","(AVPR1A, 0)","(MAS1, 0)","(ET(B)R-LP-2, 0)","(BDKRB1, 0)","(FPRL1, 0)","(GPR87, 0)","(CHRM2, 0)","(EDNRA, 0)","(CMKLR1, 0)","(CCR7, 0)","(OPRK1, 0)","(CNR1, 0)","(GPR86, 0)","(OR7C1, 0)","(CCR5, 0)","(CHRM4, 0)","(CHRM5, 0)","(CCBP2, 0)","(GPR63, 0)","(GRPR, 0)","(ADORA3, 0)","(IL8RB, 0)","(F2R, 0)","(VIPR1, 0)","(CNR2, 0)","(FPRL2, 0)","(GPR24, 0)","(P2RY5, 0)","(PTGER3, 0)","(HTR1D, 0)","(CXCR3, 0)","(AGTR1, 0)","(P2RY2, 0)","(GPR23, 0)","(ADRA1D, 0)","(HTR2A, 0)","(GPR37, 0)","(ADRA1A, 0)","(FSHR, 0)","(PTGIR, 0)","(F2RL2, 0)","(EDNRB, 0)","(CCR4, 0)","(CCKAR, 0)","(GHSR, 0)","(P2RY6, 0)","(ADORA1, 0)","(NPY1R, 0)","(GPR85, 0)","(HTR7, 0)","(OPRD1, 0)","(AGTRL1, 0)","(HTR4, 0)","(MTNR1A, 0)","(NTSR1, 0)","(HCRTR2, 0)","(CCR2, 0)","(PTGER4, 0)","(ADRB3, 0)","(MTNR1B, 0)","(AGTR2, 0)","(HRH1, 0)","(PTGER1, 0)","(NPY2R, 0)","(RRH, 0)","(HTR1E, 0)","(SREB3, 0)","(CCRL2, 0)","(CMKOR1, 0)","(HRH3, 0)","(GPR27, 0)","(BDKRB2, 0)","(GPR30, 0)","(BLR1, 0)","(FPR1, 0)","(C3AR1, 0)"]
[1190,"ST Dictyostelium discoideum cAMP Chemotaxis Pathway Signalling Transduction KE",31,0.848,1,1,"(PDE3A, 0.193)","(RPS4X, 0.173)","(VASP, 0.157)","(ANGPTL2, 0.155)","(PDE3B, 0.12)","(PI3, 0.119)","(DAG1, 0.118)","(PIK3C2G, 0.111)","(ETFA, 0.107)","(ACTR3, 0.076)","(BF, 0.04)","(MAPK3, 0.035)","(ITPR3, 0.018)","(ITGA9, 0.007)","(PIK3R1, 0.006)","(MAP2K1, 0)","(ITPKA, 0)","(ITPR1, 0)","(PAK1, -0.034)","(GCA, -0.034)","(ITPR2, -0.042)","(PIK3CA, -0.043)","(PSME1, -0.043)","(MAPK1, -0.08)","(NR1I3, -0.082)","(ITPKB, -0.103)","(AKT1, -0.133)","(ACTR2, -0.148)","(SGCB, -0.164)","(PIK3CD, -0.173)","(DGKA, -0.19)"]
[1190,"complement activation, lectin pathway (GO:0001867)",2,0.848,1,1,"(KRT1, -0.082)","(MBL2, -0.233)"]
[1193,"chromosome organization and biogenesis (sensu Eukaryota) (GO:0007001)",18,0.849,1,0.78307,"(SMC4L1, 0.397)","(CBX4, 0.288)","(EGF, 0.244)","(ATRX, 0.144)","(PSEN1, 0.101)","(SMC2L1, 0.072)","(CENPA, 0.015)","(ZNF238, -0.035)","(TWIST1, -0.039)","(CHD4, -0.047)","(TOP3A, -0.062)","(TOP3B, -0.069)","(CHD3, -0.086)","(CSPG6, -0.099)","(CHD2, -0.104)","(PSEN2, -0.119)","(H3F3B, -0.142)","(CHD1, -0.174)"]
[1193,"ST Type I Interferon Pathway Signalling Transduction KE",9,0.849,1,1,"(PTPRU, 0.182)","(JAK1, 0.128)","(STAT1, 0.064)","(STAT2, -0.005)","(IFNB1, -0.024)","(TYK2, -0.075)","(ISGF3G, -0.085)","(IFNAR1, -0.118)","(REG1A, -0.124)"]
[1195,"histone deacetylation (GO:0016575)",4,0.85,1,0.96212,"(HDAC11, 0.05)","(SIRT2, -0.059)","(PHB, -0.064)","(HDAC6, -0.191)"]
[1196,"spryPathway BioCarta",17,0.851,1,0.89328,"(EGF, 0.282)","(SPRY1, 0.281)","(MAPK3, 0.104)","(RAF1, 0.05)","(EGFR, 0.02)","(SOS1, -0.009)","(MAPK1, -0.023)","(CBL, -0.025)","(PTPRB, -0.033)","(GRB2, -0.04)","(SHC1, -0.042)","(SRC, -0.045)","(MAP2K1, -0.075)","(HRAS, -0.106)","(SPRY2, -0.157)","(RASA1, -0.187)","(SPRY4, -0.221)"]
[1196,"post-Golgi vesicle-mediated transport (GO:0006892)",7,0.851,1,1,"(AP3B2, 0.035)","(SCAMP1, 0.008)","(SCAMP2, -0.007)","(NBEA, -0.013)","(STX7, -0.133)","(SCAMP3, -0.146)","(SEC10L1, -0.196)"]
[1196,"neuromuscular junction development (GO:0007528)",2,0.851,1,1,"(CACNB2, -0.037)","(NRD1, -0.345)"]
[1199,"regulation of neurotransmitter secretion (GO:0046928)",2,0.852,1,0.91074,"(ICA1, -0.22)","(KCNMB4, -0.282)"]
[1200,"biopeptidesPathway Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases.",37,0.853,1,0.99606,"(PLCG1, 0.448)","(PTK2B, 0.423)","(MYLK, 0.273)","(FYN, 0.213)","(MAPK14, 0.172)","(MAPK3, 0.115)","(SOS1, 0.036)","(STAT5A, 0.033)","(GNB1, 0.031)","(CAMK2B, 0.017)","(RAF1, 0.015)","(CAMK2A, 0.01)","(STAT1, 0.005)","(AGTR2, 0)","(MAP2K2, -0.002)","(AGT, -0.003)","(CALM1, -0.008)","(GNAI1, -0.011)","(MAPT, -0.013)","(PRKCA, -0.03)","(GRB2, -0.033)","(MAP2K1, -0.036)","(SYT1, -0.038)","(SHC1, -0.039)","(CALM2, -0.039)","(CAMK2G, -0.041)","(MAPK8, -0.044)","(MAPK1, -0.057)","(F2, -0.066)","(HRAS, -0.066)","(CDK5, -0.071)","(GNA11, -0.088)","(CALM3, -0.092)","(PRKCB1, -0.096)","(JAK2, -0.117)","(STAT3, -0.149)","(GNGT1, -0.203)"]
[1201,"CR DEATH PNAS 2006",75,0.854,1,1,"(TRADD, 0.449)","(MXI1, 0.221)","(TNFRSF9, 0.19)","(IL17, 0.183)","(CASP3, 0.168)","(FOSL2, 0.122)","(DAPK1, 0.082)","(TRAF3, 0.075)","(CASP10, 0.047)","(GML, 0.031)","(TRAF2, 0.03)","(TNFSF6, 0.025)","(TNFRSF6, 0.019)","(BAX, 0.017)","(DPF2, 0.011)","(CASP1, 0.008)","(CASP6, 0)","(CASP7, 0)","(BAG4, 0)","(CFLAR, 0)","(NME3, 0)","(TP53BP2, 0)","(TNFRSF10B, 0)","(MYC, 0)","(TNF, 0)","(BCL2, 0)","(BCL2A1, 0)","(TNFSF10, 0)","(BAK1, 0)","(TP73, 0)","(MDM2, 0)","(TP73L, 0)","(DAXX, 0)","(BCL2L1, 0)","(BID, 0)","(LTA, 0)","(HRK, 0)","(CIDEA, 0)","(CASP9, 0)","(BNIP2, 0)","(F2R, 0)","(BFAR, 0)","(PAWR, 0)","(AATF, 0)","(BNIP3, 0)","(DAPK3, 0)","(DAP3, 0)","(EVI1, 0)","(CASP8, 0)","(MYD88, 0)","(BNIP1, 0)","(TNFSF7, 0)","(MAD, 0)","(CASP5, 0)","(BAD, 0)","(BCL2L2, 0)","(TNFSF5, 0)","(EMP1, 0)","(STK17A, 0)","(PLAGL1, 0)","(APAF1, 0)","(MAX, -0.006)","(IKBKG, -0.007)","(FADD, -0.007)","(BIK, -0.009)","(TNFRSF10D, -0.014)","(TFPT, -0.015)","(CRADD, -0.016)","(STK17B, -0.023)","(LTB, -0.024)","(CASP4, -0.03)","(TP53, -0.08)","(TNFRSF25, -0.087)","(DAP, -0.089)","(CASP2, -0.117)"]
[1202,"ST Dictyostelium discoideum cAMP Receptor G Protein Independent Pathways BLACK",4,0.856,1,0.89843,"(MAPK1, -0.03)","(PSME1, -0.084)","(COPEB, -0.114)","(NR1I3, -0.123)"]
[1202,"sphingolipid metabolism (GO:0006665)",2,0.856,1,0.92284,"(TDE2, -0.129)","(SPTLC1, -0.327)"]
[1204,"G2/M transition of mitotic cell cycle (GO:0000086)",6,0.857,1,0.89138,"(ANAPC5, 0.138)","(ANAPC10, 0.085)","(BIRC5, -0.062)","(CDK2, -0.075)","(KHDRBS1, -0.188)","(LATS1, -0.339)"]
[1204,"negative regulation of blood coagulation (GO:0030195)",2,0.857,1,0.95205,"(KNG1, 0.011)","(PROC, -0.418)"]
[1206,"mRNA processing (GO:0006397)",9,0.858,1,0.8915,"(HNRPR, 0.321)","(PPARGC1A, 0.168)","(ELAVL4, 0.135)","(SPOP, -0.021)","(CUGBP1, -0.066)","(SNRP70, -0.159)","(HNRPA0, -0.196)","(KHDRBS1, -0.201)","(HNRPA1, -0.213)"]
[1207,"ptenPathway BioCarta",17,0.86,1,0.61419,"(CDKN1B, 0.259)","(FOXO3A, 0.125)","(PDPK1, 0.117)","(MAPK3, 0.087)","(TNFSF6, 0.086)","(ITGB1, 0.004)","(PDK2, -0.02)","(SHC1, -0.03)","(ILK, -0.032)","(PIK3R1, -0.045)","(SOS1, -0.048)","(MAPK1, -0.051)","(GRB2, -0.092)","(PTK2, -0.095)","(AKT1, -0.104)","(PIK3CA, -0.127)","(PTEN, -0.264)"]
[1207,"gleevecPathway BioCarta",22,0.86,1,0.97908,"(JUN, 0.388)","(MYC, 0.147)","(FOS, 0.097)","(BCL2, 0.054)","(RAF1, 0.041)","(STAT1, 0.037)","(STAT5B, 0.02)","(STAT5A, 0.007)","(SOS1, 0.003)","(MAPK3, 0.002)","(GRB2, 0)","(PIK3R1, -0.027)","(PIK3CA, -0.039)","(CRKL, -0.047)","(HRAS, -0.053)","(MAP2K4, -0.079)","(MAP2K1, -0.087)","(MAPK8, -0.093)","(AKT1, -0.119)","(BCR, -0.13)","(MAP3K1, -0.138)","(JAK2, -0.14)"]
[1207,"positive regulation of cytokine secretion (GO:0050715)",2,0.86,1,0.99178,"(INS, -0.225)","(GLMN, -0.285)"]
[1210,"negative regulation of cell adhesion (GO:0007162)",8,0.861,1,0.67132,"(ADAM10, 0.259)","(ARHGDIG, 0.001)","(RND1, -0.006)","(TGFBI, -0.047)","(ARHGDIA, -0.069)","(KNG1, -0.071)","(SPN, -0.186)","(ARHGDIB, -0.187)"]
[1210,"regulation of neuron differentiation (GO:0045664)",2,0.861,1,0.99675,"(YWHAH, -0.055)","(NLGN1, -0.415)"]
[1212,"hydrogen ion homeostasis (GO:0030641)",3,0.863,1,1,"(ATP1A3, 0.039)","(ATP1A1, -0.243)","(ATP1A2, -0.372)"]
[1213,"keratinocyte differentiation (GO:0030216)",2,0.864,1,0.91707,"(PTGS2, -0.279)","(PTGS1, -0.327)"]
[1214,"ST JNK MAPK Pathway Signalling Transduction KE",40,0.865,1,0.86076,"(JUN, 0.267)","(ATF2, 0.256)","(MAPK7, 0.218)","(NFATC3, 0.19)","(NR2C2, 0.144)","(MAP3K9, 0.14)","(ZAK, 0.131)","(GAB1, 0.113)","(PAPPA, 0.103)","(MAP3K13, 0.041)","(MAP3K2, 0.04)","(MAP3K3, 0.004)","(MAP3K7IP1, 0)","(GCK, 0)","(DLD, 0)","(MAP3K5, -0.006)","(MAP3K12, -0.007)","(IL1R1, -0.009)","(DUSP8, -0.011)","(DUSP4, -0.012)","(MAP3K11, -0.017)","(AKT1, -0.022)","(MAP3K1, -0.023)","(MAPK8, -0.023)","(TP53, -0.03)","(TRAF6, -0.054)","(MAP2K7, -0.054)","(CDC42, -0.055)","(MAPK9, -0.056)","(MAP3K7, -0.062)","(MAP3K10, -0.073)","(MAPK10, -0.09)","(MAP2K4, -0.091)","(GADD45A, -0.094)","(DUSP10, -0.095)","(MYEF2, -0.105)","(SHC1, -0.111)","(MAP2K5, -0.159)","(MAP3K4, -0.192)","(MAP3K7IP2, -0.204)"]
[1214,"negative regulation of transcription, DNA-dependent (GO:0045892)",15,0.865,1,1,"(ILF3, 0.376)","(ZHX3, 0.051)","(DAXX, 0.043)","(KLF4, 0.008)","(ARID4A, 0.006)","(RBPSUH, 0.005)","(SMARCE1, 0.003)","(HBXAP, -0.051)","(PCOLN3, -0.097)","(ARID5B, -0.103)","(BCOR, -0.103)","(TP73L, -0.104)","(ING4, -0.11)","(ZHX2, -0.135)","(SMARCC2, -0.139)"]
[1216,"urea transport (GO:0015840)",2,0.866,1,0.99317,"(SLC14A2, -0.012)","(SLC14A1, -0.635)"]
[1217,"fibroblast growth factor receptor signaling pathway (GO:0008543)",4,0.867,1,0.96858,"(FIBP, 0.104)","(FGF5, 0.002)","(FGFR4, -0.212)","(FGFR3, -0.278)"]
[1218,"calcium ion homeostasis (GO:0006874)",22,0.868,1,0.65688,"(CXCL12, 0.212)","(TRPV5, 0.177)","(CCL3, 0.171)","(CCL23, 0.109)","(CCL15, 0.072)","(ATP2C1, 0.067)","(CCL1, 0.019)","(CCL7, 0.006)","(STC1, -0.032)","(CCL11, -0.034)","(CASR, -0.035)","(CYP27B1, -0.044)","(XCL1, -0.047)","(TRPV4, -0.053)","(CCL19, -0.065)","(CALCB, -0.068)","(S100B, -0.073)","(CCL2, -0.112)","(CCL13, -0.112)","(CALR, -0.123)","(CCL14, -0.127)","(CCL5, -0.175)"]
[1219,"cholesterol metabolism (GO:0008203)",16,0.869,1,0.8595,"(STARD3, 0.187)","(PPARD, 0.149)","(SCARB1, 0.096)","(APOA1, 0.085)","(ELA3A, 0.062)","(ELA3B, 0.028)","(MBTPS2, -0.035)","(NR0B2, -0.037)","(SOAT1, -0.057)","(SOAT2, -0.07)","(HDLBP, -0.104)","(APOL2, -0.107)","(CETP, -0.128)","(NR1H4, -0.152)","(IL4, -0.154)","(APOF, -0.209)"]
[1220,"ubiquinone biosynthesis (GO:0006744)",2,0.871,1,0.99164,"(COQ3, -0.324)","(COQ7, -0.327)"]
[1220,"MAPKKK cascade GO",9,0.871,1,1,"(MAP3K3, 0.094)","(NRTN, 0.034)","(DUSP7, 0.012)","(MAP3K5, -0.017)","(DUSP6, -0.022)","(FGFR1, -0.084)","(DUSP4, -0.113)","(MAPKAPK2, -0.125)","(FGFR3, -0.15)"]
[1222,"transformed cell apoptosis (GO:0006927)",2,0.873,1,0.9211,"(RHOB, -0.172)","(PRF1, -0.309)"]
[1222,"ST G alpha i Pathway  Signalling Transduction KE",36,0.873,1,1,"(AKT2, 0.502)","(RAP1GA1, 0.211)","(PIK3CB, 0.208)","(SOS2, 0.139)","(RGS20, 0.108)","(BF, 0.098)","(DAG1, 0.093)","(PI3, 0.06)","(ITPR3, 0.046)","(SOS1, 0.044)","(KCNJ5, 0.023)","(GRB2, 0.022)","(RAF1, 0.02)","(ITPKA, 0.016)","(MAPK1, 0.007)","(BRAF, 0.004)","(ITPR1, 0.004)","(EGFR, 0)","(PLCB2, 0)","(DRD2, 0)","(PLCB3, 0)","(PITX2, -0.004)","(ASAH1, -0.008)","(ITPKB, -0.018)","(ITPR2, -0.02)","(AKT3, -0.029)","(TERF2IP, -0.039)","(SRC, -0.062)","(PLCB1, -0.075)","(PLCB4, -0.078)","(SHC1, -0.081)","(AKT1, -0.091)","(EPHB2, -0.105)","(KCNJ9, -0.121)","(KCNJ3, -0.127)","(STAT3, -0.147)"]
[1224,"membrane lipid metabolism (GO:0006643)",2,0.876,1,0.93141,"(B4GALT4, -0.079)","(APOM, -0.446)"]
[1224,"MAP00531 Glycosaminoglycan degradation GenMAPP",10,0.876,1,1,"(HEXA, 0.161)","(NAGLU, 0.01)","(GNS, -0.007)","(ARSB, -0.04)","(GUSB, -0.045)","(GLB1, -0.051)","(GALNS, -0.103)","(IDUA, -0.141)","(IDS, -0.149)","(HEXB, -0.184)"]
[1226,"mitochondrial genome maintenance (GO:0000002)",2,0.877,1,0.9573,"(ECGF1, 0.002)","(SLC25A4, -0.373)"]
[1227,"il2Pathway BioCarta",22,0.878,1,0.99207,"(JUN, 0.414)","(FOS, 0.163)","(IL2RA, 0.069)","(JAK1, 0.064)","(IL2RB, 0.053)","(RAF1, 0.044)","(MAPK3, 0.015)","(STAT5B, 0.001)","(SOS1, -0.006)","(SHC1, -0.01)","(GRB2, -0.034)","(HRAS, -0.039)","(JAK3, -0.055)","(STAT5A, -0.057)","(MAP2K1, -0.058)","(MAPK8, -0.063)","(IL2, -0.099)","(ELK1, -0.111)","(LCK, -0.13)","(SYK, -0.134)","(IL2RG, -0.134)","(CSNK2A1, -0.171)"]
[1228,"regulation of translational initiation (GO:0006446)",19,0.88,1,0.76077,"(GC20, 0.249)","(EIF4G3, 0.229)","(EIF3S4, 0.203)","(EIF5, 0.086)","(EIF3S8, 0.072)","(EIF3S5, 0.045)","(EIF2C1, 0)","(EIF3S2, -0.012)","(EIF3S1, -0.013)","(EIF3S3, -0.018)","(EIF4G2, -0.029)","(HSPB1, -0.033)","(WBSCR1, -0.06)","(EIF3S10, -0.07)","(MTIF2, -0.096)","(SUI1, -0.119)","(EIF4B, -0.141)","(EIF4A2, -0.178)","(EIF3S7, -0.189)"]
[1229,"hemocyte development (sensu Arthropoda) (GO:0007516)",6,0.881,1,0.91136,"(RAB3D, 0.143)","(RPS19, -0.007)","(MAP4K2, -0.026)","(RAG1, -0.13)","(MAL, -0.136)","(PRL, -0.293)"]
[1229,"g2Pathway BioCarta",23,0.881,1,0.91303,"(ATR, 0.249)","(CHEK1, 0.138)","(CDC25B, 0.131)","(BRCA1, 0.097)","(MYT1, 0.04)","(CDC25A, 0.031)","(RPS6KA1, 0.018)","(WEE1, 0.01)","(EP300, 0.003)","(CHEK2, -0.012)","(CDC2, -0.014)","(CDC34, -0.014)","(YWHAH, -0.018)","(TP53, -0.024)","(CDKN1A, -0.061)","(PRKDC, -0.073)","(GADD45A, -0.081)","(CDKN2D, -0.083)","(CCNB1, -0.088)","(ATM, -0.088)","(YWHAQ, -0.096)","(MDM2, -0.096)","(CDC25C, -0.123)"]
[1229,"base-excision repair (GO:0006284)",7,0.881,1,0.92564,"(UNG2, 0.195)","(OGG1, 0.057)","(TP53, 0.02)","(MPG, -0.087)","(TDG, -0.131)","(APEX1, -0.161)","(UNG, -0.214)"]
[1232,"transforming growth factor beta receptor complex assembly (GO:0007181)",3,0.883,1,0.85705,"(TGFBR1, -0.027)","(ZFYVE9, -0.143)","(FMOD, -0.316)"]
[1232,"edg1Pathway The lipid S1P is an EDG1 ligand promoting chemotaxis via Rac1 and cell survival and proliferation via ERK activation.",25,0.883,1,1,"(ITGAV, 0.497)","(RAC1, 0.287)","(SKIP, 0.067)","(ADCY1, 0.064)","(MAPK3, 0.057)","(SPHK1, 0.049)","(PDGFRA, 0.041)","(PDGFA, 0.025)","(GNAI1, 0.01)","(SMPD1, 0.006)","(ITGB3, -0.01)","(GNB1, -0.011)","(EDG1, -0.011)","(SRC, -0.012)","(PLCB1, -0.016)","(MAPK1, -0.027)","(PIK3R1, -0.044)","(PRKCB1, -0.083)","(PTK2, -0.107)","(ASAH1, -0.117)","(PIK3CA, -0.123)","(AKT1, -0.148)","(PRKCA, -0.156)","(SMPD2, -0.175)","(GNGT1, -0.21)"]
[1234,"ST G Protein Independent 7 Transmembrane BLACK",4,0.884,1,0.9457,"(MAPK1, -0.084)","(EPHB2, -0.09)","(SOAT1, -0.113)","(CXADR, -0.246)"]
[1234,"ST G Protein Independent 7 Transmembrane Receptor Signaling BLACK",4,0.884,1,0.9457,"(SOAT1, -0.007)","(MAPK1, -0.062)","(EPHB2, -0.14)","(CXADR, -0.303)"]
[1234,"microtubule-based movement (GO:0007018)",5,0.884,1,0.97741,"(KIF13B, 0.268)","(KIF1B, 0.086)","(KIF5B, -0.167)","(KIF5A, -0.178)","(KTN1, -0.189)"]
[1237,"meiosis (GO:0007126)",11,0.887,1,0.99579,"(REC8L1, 0.268)","(ZW10, 0.197)","(MSH5, 0.126)","(DMC1, 0.087)","(RAD54L, -0.048)","(TOP3A, -0.057)","(DUSP13, -0.065)","(SMC1L1, -0.093)","(CSPG6, -0.101)","(XRCC2, -0.137)","(RAD51, -0.241)"]
[1238,"positive regulation of transcription (GO:0045941)",6,0.889,1,0.93721,"(YAF2, 0.088)","(UBA52, -0.005)","(CAMKK2, -0.009)","(JARID1A, -0.031)","(IRF4, -0.178)","(ARNT2, -0.241)"]
[1239,"pitx2Pathway BioCarta",16,0.89,1,1,"(GSK3B, 0.164)","(AXIN1, 0.116)","(LDB1, 0.06)","(EP300, 0.034)","(HDAC1, 0.007)","(HTATIP, -0.005)","(DVL1, -0.019)","(TRRAP, -0.024)","(PITX2, -0.046)","(CTNNB1, -0.078)","(FZD1, -0.082)","(LEF1, -0.089)","(CREBBP, -0.089)","(APC, -0.109)","(PPARBP, -0.13)","(WNT1, -0.166)"]
[1240,"ifnaPathway BioCarta",9,0.891,1,0.99234,"(STAT1, 0.104)","(JAK1, 0.101)","(ISGF3G, -0.054)","(IFNB1, -0.055)","(STAT2, -0.066)","(IFNAR1, -0.085)","(TYK2, -0.089)","(IFNAR2, -0.118)","(IFNA1, -0.145)"]
[1240,"ATP hydrolysis coupled proton transport (GO:0015991)",3,0.891,1,1,"(ATP1A3, -0.007)","(ATP1A1, -0.233)","(ATP1A2, -0.361)"]
[1242,"MAPKKK cascade (GO:0000165)",8,0.892,1,0.99421,"(MAP3K3, 0.093)","(NRTN, 0.064)","(MAP3K5, 0.026)","(FGFR1, -0.047)","(CAMKK2, -0.05)","(DUSP4, -0.124)","(MAPKAPK2, -0.138)","(FGFR3, -0.218)"]
[1243,"regulation of action potential (GO:0001508)",5,0.893,1,0.85709,"(KCNMB2, 0.281)","(KCNMB3, -0.177)","(KCND2, -0.183)","(SRI, -0.196)","(KCNMB4, -0.219)"]
[1244,"oxidative phosphorylation (GO:0006119)",4,0.894,1,0.92022,"(UQCRH, 0.027)","(UQCRB, -0.027)","(UQCRC2, -0.21)","(UQCRC1, -0.255)"]
[1244,"regulation of mRNA processing (GO:0050684)",2,0.894,1,0.92479,"(CDC2L2, -0.146)","(CDC2L1, -0.426)"]
[1244,"igf1rPathway BioCarta",15,0.894,1,1,"(IRS1, 0.113)","(BAD, 0.08)","(MAPK3, 0.058)","(YWHAH, 0.02)","(RAF1, 0.009)","(GRB2, 0.001)","(MAPK1, -0.006)","(SOS1, -0.006)","(SHC1, -0.013)","(PIK3R1, -0.017)","(HRAS, -0.035)","(IGF1R, -0.053)","(MAP2K1, -0.055)","(AKT1, -0.092)","(PIK3CA, -0.166)"]
[1247,"negative regulation of DNA replication (GO:0008156)",3,0.898,1,0.9594,"(S100A11, -0.013)","(GMNN, -0.161)","(CDC6, -0.338)"]
[1248,"cell migration (GO:0016477)",4,0.899,1,0.95045,"(TNN, 0.214)","(ABI2, -0.247)","(NRD1, -0.255)","(WNT1, -0.26)"]
[1248,"DNA damage induced protein phosphorylation (GO:0006975)",2,0.899,1,0.99384,"(MAPK12, -0.338)","(MAP2K6, -0.385)"]
[1250,"myelination (GO:0042552)",2,0.9,1,0.9956,"(MAL, -0.124)","(LARGE, -0.485)"]
[1251,"myosinPathway BioCarta",15,0.903,1,0.90376,"(MYLK, 0.387)","(ROCK1, 0.189)","(ARHGEF1, 0.096)","(GNB1, 0.085)","(ARHGAP5, 0.026)","(GNA12, -0.023)","(GNA13, -0.032)","(PPP1R12B, -0.069)","(PRKCL1, -0.071)","(GNAQ, -0.079)","(PLCB1, -0.1)","(MYL2, -0.107)","(PRKCB1, -0.115)","(GNGT1, -0.165)","(PRKCA, -0.194)"]
[1252,"DNA dealkylation (GO:0006307)",2,0.904,1,0.99655,"(ALKBH, -0.185)","(MPG, -0.396)"]
[1253,"MAP00532 Chondroitin Heparan sulfate biosynthesis GenMAPP",7,0.905,1,0.89063,"(B3GAT3, 0.434)","(HS3ST2, -0.099)","(B4GALT7, -0.172)","(XYLT2, -0.172)","(HS3ST3A1, -0.178)","(HS3ST1, -0.216)","(HS3ST3B1, -0.226)"]
[1253,"MAP00140 C21 Steroid hormone metabolism GenMAPP",10,0.905,1,0.92012,"(CYP17A1, 0.085)","(HSD11B2, 0.014)","(CYP21A2, -0.009)","(HSD3B2, -0.021)","(HSD11B1, -0.034)","(CYP11B1, -0.091)","(AKR1D1, -0.101)","(CYP11B2, -0.156)","(HSD3B1, -0.16)","(CYP11A1, -0.193)"]
[1255,"phospholipase C activation (GO:0007202)",14,0.908,1,0.71771,"(AVPR1A, 0.119)","(EDG4, 0.061)","(AVPR1B, 0.014)","(CCKBR, 0.008)","(EGFR, -0.037)","(EDNRA, -0.043)","(GNAQ, -0.066)","(EDG6, -0.07)","(CALCA, -0.076)","(PLCB2, -0.076)","(EDG2, -0.091)","(CALCR, -0.101)","(GNA15, -0.147)","(C5R1, -0.153)"]
[1256,"S1P Signaling BioCarta",23,0.909,1,1,"(AKT2, 0.646)","(MAPK3, 0.13)","(MAPK7, 0.117)","(GNAI3, 0.107)","(MAPK6, 0.056)","(EDG1, 0.024)","(AKT3, -0.003)","(MAPK1, -0.01)","(SPHK1, -0.013)","(RACGAP1, -0.02)","(EDG5, -0.034)","(SPHK2, -0.046)","(ASAH1, -0.047)","(EDG8, -0.062)","(MAPK4, -0.071)","(AKT1, -0.08)","(PLCB2, -0.082)","(PLCB3, -0.082)","(GNAI1, -0.099)","(MAPK12, -0.101)","(PLCB1, -0.104)","(GNAI2, -0.118)","(PIK3C2B, -0.154)"]
[1256,"proteoglycan metabolism (GO:0006029)",3,0.909,1,1,"(LECT1, 0.011)","(B4GALT7, -0.248)","(SGSH, -0.276)"]
[1258,"hemolysis of host red blood cells (GO:0019836)",2,0.912,1,0.93072,"(C9, -0.287)","(PRF1, -0.375)"]
[1258,"integrin-mediated signaling pathway (GO:0007229)",8,0.912,1,0.96106,"(ERBB2IP, 0.19)","(ILK, 0.103)","(ADAMTS1, -0.067)","(CD47, -0.073)","(DOCK1, -0.103)","(PTK2, -0.145)","(ADAM11, -0.174)","(LAT, -0.178)"]
[1260,"axonogenesis (GO:0007409)",10,0.915,1,0.57483,"(PARD3, 0.164)","(APBB2, 0.115)","(BAI1, 0.046)","(APBB1, 0.014)","(PARD6B, -0.042)","(PAX2, -0.047)","(POU4F1, -0.122)","(DCC, -0.124)","(S100B, -0.147)","(NTNG1, -0.211)"]
[1260,"muscle cell differentiation (GO:0042692)",2,0.915,1,0.99685,"(SYNE1, -0.207)","(GLMN, -0.358)"]
[1262,"ca nf at signalling GEArray",98,0.916,1,1,"(VAV1, 0.462)","(SFN, 0.291)","(NFATC1, 0.218)","(IL8RA, 0.186)","(GATA4, 0.184)","(NFATC3, 0.135)","(TRAF2, 0.116)","(MAPK14, 0.115)","(GSK3B, 0.111)","(GRLF1, 0.107)","(PPP3CC, 0.093)","(CD3E, 0.091)","(CEBPB, 0.077)","(BAD, 0.058)","(RPL13A, 0.048)","(GSK3A, 0.026)","(IL13, 0)","(CD3Z, 0)","(EGR3, 0)","(RELA, 0)","(SLA, 0)","(CALM1, 0)","(TRPV6, 0)","(ITK, 0)","(MAP2K7, 0)","(PPP3R1, 0)","(CALM3, 0)","(MEF2B, 0)","(TNF, 0)","(EP300, 0)","(IFNG, 0)","(IL1B, 0)","(HRAS, 0)","(CNR1, 0)","(PIN1, 0)","(MEF2A, 0)","(IL10, 0)","(CREBBP, 0)","(GATA3, 0)","(JUNB, 0)","(FCGR3A, 0)","(NFAT5, 0)","(CD3G, 0)","(PAK1, 0)","(SP3, 0)","(CALM2, 0)","(PPIA, 0)","(MYF5, 0)","(FKBP1B, 0)","(IL8, 0)","(CAMK4, 0)","(MAPK9, 0)","(TNFSF5, 0)","(IL6, 0)","(TNFSF6, 0)","(FLJ14639, 0)","(OPRD1, 0)","(FOSL1, 0)","(ICOS, 0)","(IL4, 0)","(MEF2D, 0)","(NFKBIB, 0)","(IL2RA, 0)","(BCL2, 0)","(NUP214, 0)","(IFNB1, 0)","(VEGF, 0)","(VAV3, 0)","(CSNK2A1, 0)","(KPNA5, 0)","(P2RX7, 0)","(IFNA1, 0)","(VAV2, 0)","(TGFB1, 0)","(MAPK8, 0)","(IL2, 0)","(CABIN1, 0)","(CSNK2B, 0)","(CTLA4, 0)","(SP1, 0)","(CSF2, 0)","(NPPB, 0)","(KPNB3, 0)","(NFKB2, 0)","(FCER1A, 0)","(NFKBIE, 0)","(IL3, 0)","(CD69, 0)","(GAPD, 0)","(CAMK2B, 0)","(NFATC4, 0)","(FOS, 0)","(CDKN1A, 0)","(NCK2, 0)","(EGR2, 0)","(ACTB, 0)","(PTPRC, -0.009)","(PPP3CB, -0.016)"]
[1263,"regulation of protein secretion (GO:0050708)",2,0.917,1,0.9394,"(INS, -0.237)","(DNAJC1, -0.411)"]
[1264,"mitotic spindle organization and biogenesis (GO:0007052)",7,0.922,1,0.67047,"(UNC84B, 0.118)","(KIF11, 0.082)","(TUBG1, -0.02)","(TTK, -0.124)","(CSPG6, -0.155)","(SMC1L1, -0.158)","(RAN, -0.269)"]
[1264,"post-chaperonin tubulin folding pathway (GO:0007023)",2,0.922,1,0.96,"(TBCC, -0.391)","(TBCA, -0.391)"]
[1266,"negative regulation of Wnt receptor signaling pathway (GO:0030178)",2,0.924,1,0.99395,"(FRZB, -0.123)","(NLK, -0.41)"]
[1267,"insemination (GO:0007320)",2,0.925,1,0.96069,"(TAC1, -0.339)","(SEMG1, -0.523)"]
[1268,"DNA replication initiation (GO:0006270)",8,0.927,1,0.98729,"(ORC1L, 0.189)","(PURA, 0.049)","(ORC4L, 0.039)","(CDC7, -0.096)","(ORC5L, -0.158)","(ORC2L, -0.254)","(CDC45L, -0.261)","(MCM3, -0.276)"]
[1269,"phosphate transport (GO:0006817)",2,0.93,1,0.9303,"(SLC34A1, -0.188)","(SLC17A1, -0.394)"]
[1270,"fosbPathway BLACK",4,0.933,1,1,"(JUND, 0.086)","(GRIA2, -0.135)","(CDK5, -0.143)","(FOSB, -0.319)"]
[1271,"beta-tubulin folding (GO:0007025)",3,0.938,1,0.93499,"(TBCC, -0.301)","(TBCA, -0.313)","(RP2, -0.322)"]
[1272,"JAK-STAT cascade (GO:0007259)",18,0.939,1,0.81081,"(SOCS1, 0.304)","(PIAS1, 0.198)","(CCR2, 0.083)","(IFNAR1, 0.018)","(STAT5A, 0.009)","(STAT2, -0.003)","(SOCS3, -0.006)","(STAT4, -0.024)","(STAT5B, -0.04)","(SOCS2, -0.088)","(SOCS6, -0.093)","(IFNAR2, -0.11)","(SOCS5, -0.111)","(CCL2, -0.136)","(NMI, -0.144)","(JAK2, -0.15)","(STAT3, -0.152)","(FGFR3, -0.161)"]
[1273,"positive regulation of interleukin-2 biosynthesis (GO:0045086)",2,0.941,1,0.99928,"(GLMN, -0.298)","(IRF4, -0.385)"]
[1274,"leptinPathway BioCarta",10,0.942,1,0.85086,"(PRKAB1, 0.129)","(LEP, 0.083)","(PRKAG2, 0.041)","(PRKAA2, -0.042)","(ACACA, -0.059)","(PRKAG1, -0.091)","(PRKAA1, -0.126)","(PRKAB2, -0.131)","(LEPR, -0.149)","(CPT1A, -0.219)"]
[1275,"cAMP metabolism (GO:0046058)",2,0.949,1,0.9211,"(PTHLH, -0.362)","(PTH, -0.464)"]
[1276,"cell recognition (GO:0008037)",2,0.95,1,0.92171,"(CSPG2, -0.382)","(PECAM1, -0.489)"]
[1277,"anti-inflammatory response (GO:0030236)",2,0.959,1,0.99429,"(AMBP, -0.454)","(PROC, -0.513)"]
[1278,"negative regulation of cyclin dependent protein kinase activity (GO:0045736)",2,0.961,1,0.92391,"(CDK5RAP1, -0.428)","(LATS1, -0.611)"]
[1279,"fatty acid alpha-oxidation (GO:0001561)",2,0.965,1,0.94261,"(HAO2, -0.456)","(HAO1, -0.523)"]
[1279,"traversing start control point of mitotic cell cycle (GO:0007089)",6,0.965,1,1,"(CDC2, -0.019)","(CDK2, -0.057)","(CDC7, -0.144)","(CDK10, -0.245)","(CDC6, -0.252)","(CDC25C, -0.254)"]
[1281,"serotonin receptor signaling pathway (GO:0007210)",2,0.967,1,0.9353,"(HTR2A, -0.406)","(HTR2C, -0.638)"]
[1282,"tubbyPathway BioCarta",6,0.97,1,0.93002,"(GNB1, 0.12)","(GNAQ, -0.127)","(PLCB1, -0.174)","(TUB, -0.191)","(HTR2C, -0.356)","(GNGT1, -0.385)"]