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["Additional Data File Table S2"]
["Table S2 is provided in Excel and tab delimited format.  Table of coordinates for the 11 gaps and four deletions in the initial chromosome 22 sequence mapped onto selected genome builds.  As clones were added into gaps the gaps sizes were adjusted, based on their size estimates.  Once closed the gap is labelled “Closed”.  Coordinates for the sequences comprising the full gap closures in this build (as shown in supplementary figures 4-13, to be released as HGRC37) are given in the final column.  Full details of the assembly are provided in the AGP file at http://www.sanger.ac.uk/HGP/Chr22/GapClosure/chr22.agp. For the deletions the initial sequence coordinates are given up to the point a sequence was replaced (“Replaced”) and then the coordinates for the replacement sequence(s) are given below.  N/A indicates that there are no coordinates for these replacement sequences in this build.  Additional Notes (1) Initial Sequence of Chromosome 22 as published in Dunham et al 1999. No adjustment for 22p or Centromere.  (2) No adjustment for 22p or Centromere. (3) Adjustment for 22p and Centromere added. (4) Data from this paper. Release date for full genome build currently unknown.  Appended below the table is the tile path file (tpf) that allows decoding of clone names to accession numbers and vice versa."]
[null,"Build (Date)"]
["Gap","Dunham et al (Dec 1999)(1)","hg4 (Sep 2000)(2)","hg6 (Dec 2000) (3)","hg10 (Dec 2001)","hg13 (Nov 2002)","hg15 (April 2003)","hg16, NCBI34 (Jul 2003)","hg17, NCBI35 (May 2004)","hg18, NCBI36 (Mar 2006)","hg19, HGRC37 (4)","hg19, HGRC37 Gap Closures"]
[]
["Gap A","234055-244656","234056-235954","13234056-13235954","13334227-13336124","13234227-13236124","14664227-14666126","14664227-14666126","14664227-14666126","Closed","Closed","14664227-14694096"]
["Gap B","650880-802481","642180-792179","13642180-13792179","13742350-13892347","13642350-13792347","15072405-15222404","15072405-15222404","15072405-15222404","15077851-15227850","15077851-15227850"]
["Gap C","2196694-2399095","Closed","Closed","Closed","Closed","Closed","Closed","Closed","Closed","Closed","16618227-16977306"]
["Gap D","4189353-4290954","4249653-4349651","17249653-17349651","17349749-17499746","17249749-17399746","18883986-18933985","18883986-18933985","18883986-18933985","18889432-18939431","18889432-18939431"]
["Gap 1","27296804-27348405","27397755-27447753","40397755-40447753","40583691-40633688","40483691-40533688","42112199-42162198","42112199-42162198","42210288-42221287","42215734-42227733","Closed","42211202-42246887"]
["Gap 2","28115760-28192361","28215111-28290109","41215111-41290109","41401046-41476043","41301046-41376043","42967356-43010355","42967356-43010355","43033957-43053956","43057959-43107958","Closed","43014245-43072667"]
["Gap 3","29720434-29872035","29818182-29968183","42818182-42968183","43004116-43154113","42904116-43054113","44545358-44632357","44545358-44632357","44687808-44707807","Closed","Closed","44594962-44819797"]
["Gap 4","32356695-32408296","32456877-32506875","45456877-45506875","45642807-45692804","45542807-45592804","47189443-47239442","47189443-47239442","47297721-47309720","47356151-47366250","Closed","47307150-47474424"]
["Gap 5","32598309-32699910","32696890-32796889","45696890-45796889","45882819-45982816","45782819-45882816","47453944-47512943","47453944-47512943","Closed","Closed","Closed","47534285-47627749"]
["Gap 6","33692738-33794339","33790592-33890591","46790592-46890591","46976519-47076516","46876519-46976516","48543038-48607037","48543038-48607037","48677467-48727466","48750437-48767136","48694167-48699166"]
["Gap 7","34084844-34186445","34181098-34281097","47181098-47281097","47367023-47467020","47267023-47367020","48897544-48937543","48897544-48937543","49045082-49070081","49087577-49089176","Closed","48999903-49149386"]
[]
["Deletion"]
[]
["RP4-633O19, AL022302","20223459-20271494","20324509-20372444","33324509-33372444","33510445-33558380","33410445-33458380","35038953-35086888","35038953-35086888","Replaced","Replaced","Replaced"]
["dJ633O19A/fW80423F1/dJ633O19B, CR383703/BX470187/CR383704","N/A","N/A","N/A","N/A","N/A","N/A","N/A","35091640-35168349","35097086-35173795","35097086-35173795"]
[]
["RP5-824I19, AL009049","19335500-19346143","19436550-19447093","32436550-32447093","32622486-32633029","32522486-32533029","34150994-34161537","34150994-34161537","Replaced","Replaced","Replaced"]
["RP5-824I19A/CITF22-91B8/CITF22-37A6/RP5-824I19B, CR381707/BX936361/BX927085/CR381709","N/A","N/A","N/A","N/A","N/A","N/A","N/A","34150994-34214224","34156440-34219670","34156440-34219670"]
[]
["RP1-257I20, AL021878","25905608-26020454","26006658-26121404","39006658-39121404","39192594-39307340","39092594-39207340","40721103-40835848","40721103-40835848","Revised","Revised","Revised"]
["RP1-257I20/RP4-669P10, AL021878/BX247885","N/A","N/A","N/A","N/A","N/A","N/A","N/A","40802564-40974262","40808010-40979708","40808010-40979708"]
[]
["CTA-437G10, AL022330","11610320-11724390","Replaced","Replaced","Replaced","Replaced","Replaced","Replaced","Replaced","Replaced","Replaced"]
["RP1-213J1pA/CTA-437G10A/RP1-213J1pB/RP11-375H17/CTA-437G10B, AL133397/AL390209/AL133398/AL121885/AL390210","N/A","11655148-11813384","24655148-24813384","24805243-24963479","24705243-24863479","26333701-26491937","26333701-26491937","26333701-26491937","26339147-26497383","26339147-26497383"]
[]
[null,"(1) Initial Sequence of Chromosome 22 as published in Dunham et al 1999. No adjustment for 22p or Centromere.  "]
[null,"(2) No adjustment for 22p or Centromere"]
[null,"(3) Adjustment for 22p and Centromere added"]
[null,"(4) Data from this paper. Release date for full genome build currently unknown."]
["Tile Path File"]
["GAP","type-4",11330000,"short_arm"]
["GAP","type-4",3000000,"centromere"]
["GAP","type-4",100000]
["AP000522","c4G1","Chr_22ctg1"]
["AP000523","c60H5","Chr_22ctg1"]
["AP000524","c70D1","Chr_22ctg1"]
["AP000525","N14H11","Chr_22ctg1"]
["AP000526","N64E9","Chr_22ctg1"]
["AP000527","c83F12","Chr_22ctg1"]
["AP000528","c91G6","Chr_22ctg1"]
["AP000529","c3G11","Chr_22ctg1"]
["CR545463","G248P-1690I13","Chr_22ctg1"]
["AP000530","c65E1","Chr_22ctg1"]
["AP000531","c59E1","Chr_22ctg1"]
["AP000532","c2F2","Chr_22ctg1"]
["AP000533","c60G3","Chr_22ctg1"]
["AP000534","c23H5","Chr_22ctg1"]
["AP000535","c58F10","Chr_22ctg1"]
["AP000536","c64C8","Chr_22ctg1"]
["AP000537","c54B2","Chr_22ctg1"]
["AP000538","c65B12","Chr_22ctg1"]
["AP000539","c72E11","Chr_22ctg1"]
["AP000540","c53D1","Chr_22ctg1"]
["AP000541","c13E4","Chr_22ctg1"]
["AP000542","c60D12","Chr_22ctg1"]
["GAP","type-4",150000]
["AP000543","c20H12","Chr_22ctg2"]
["AP000544","c17H1","Chr_22ctg2"]
["AP000545","c68B10","Chr_22ctg2"]
["AP000546","c18E3","Chr_22ctg2"]
["AP000547","KB67B5","Chr_22ctg2"]
["AP000365","KB7G2","Chr_22ctg2"]
["AC005301","p15j16","Chr_22ctg2"]
["AC007064","p87o8","Chr_22ctg2"]
["AC006548","p20k14","Chr_22ctg2"]
["AC006946","p109l3","Chr_22ctg2"]
["AC005300","p143i13","Chr_22ctg2"]
["AC005399","p238m15","Chr_22ctg2"]
["AC004019","357f7","Chr_22ctg2"]
["AC007666","p273a17","Chr_22ctg2"]
["AC006285","p1087l10","Chr_22ctg2"]
["AC016026","b461k10","Chr_22ctg2"]
["AC016027","b476c20","Chr_22ctg2"]
["AC008079","bac519d21","Chr_22ctg2"]
["AC008132","pac995o6","Chr_22ctg2"]
["AC008103","pac699j1","Chr_22ctg2"]
["AC007326","p423","Chr_22ctg2"]
["AC000095","f41c7","Chr_22ctg2"]
["AC004461","119f4","Chr_22ctg2"]
["AC004462","18c3","Chr_22ctg2"]
["AC004471","111f11","Chr_22ctg2"]
["AC004463","79h12","Chr_22ctg2"]
["L77569","dgcrtel","Chr_22ctg2"]
["AC000081","59c10","Chr_22ctg2"]
["AC000094","f39e1","Chr_22ctg2"]
["AC000085","72f8","Chr_22ctg2"]
["AC000092","98c4","Chr_22ctg2"]
["AC000079","49c12","Chr_22ctg2"]
["AC000068","102g9","Chr_22ctg2"]
["AC000087","83c5","Chr_22ctg2"]
["AC000088",{"v":8300000000,"d":"8.30E+09"},"Chr_22ctg2"]
["AC000082","59f1","Chr_22ctg2"]
["AC000070","105a","Chr_22ctg2"]
["AC000086","81h","Chr_22ctg2"]
["AC000077","31e","Chr_22ctg2"]
["AC002475","dgcr-gap1","Chr_22ctg2"]
["AC000067","100h","Chr_22ctg2"]
["AC000093","carlaa","Chr_22ctg2"]
["AC000091","91c","Chr_22ctg2"]
["AC000089","89h","Chr_22ctg2"]
["AC000076","2h","Chr_22ctg2"]
["AC000078","33e","Chr_22ctg2"]
["AC000090","8c","Chr_22ctg2"]
["AC000080","56c","Chr_22ctg2"]
["AC005663","p888c9","Chr_22ctg2"]
["AC006547","p158l19","Chr_22ctg2"]
["AC007663","b444p24","Chr_22ctg2"]
["AC024070","chk89","Chr_22ctg2"]
["AC023490","b33l19","Chr_22ctg2"]
["GAP","type-4",50000]
["AC011718","b2280l11","Chr_22ctg3"]
["AC007731","b562f10","Chr_22ctg3"]
["AC005500","p52f6","Chr_22ctg3"]
["AC004033","p_m11","Chr_22ctg3"]
["AC007050","bac32","Chr_22ctg3"]
["AC007308","pac408","Chr_22ctg3"]
["AC002470","b135h6","Chr_22ctg3"]
["AC002472","p_n5","Chr_22ctg3"]
["AP000550","KB1592A4","Chr_22ctg3"]
["AP000551","KB876E2","Chr_22ctg3"]
["AP000552","KB1183D5","Chr_22ctg3"]
["AP000556","KB1172D5","Chr_22ctg3"]
["AP000557","KB1323B2","Chr_22ctg3"]
["AP000558","KB1802C5","Chr_22ctg3"]
["AP000553","KB1440D3","Chr_22ctg3"]
["AP000554","KB666H9","Chr_22ctg3"]
["AP000555","KB1027C11","Chr_22ctg3"]
["D86995","LL22NC03-109G12","Chr_22ctg3"]
["D87019","LL22NC03-86G7","Chr_22ctg3"]
["D87012","LL22NC03-61D6","Chr_22ctg3"]
["D88268","LL22NC03-47H9","Chr_22ctg3"]
["D86993","LL22NC03-23C6","Chr_22ctg3"]
["D87004","LL22NC03-4E7","Chr_22ctg3"]
["D87022","LL22NC03-88E1","Chr_22ctg3"]
["D88271","LL22NC03-114H4","Chr_22ctg3"]
["D88269","LL22NC03-33B6","Chr_22ctg3"]
["D87000","LL22NC03-30E12","Chr_22ctg3"]
["D86996","LL22NC03-23F1","Chr_22ctg3"]
["D86989","LL22NC03-110H3","Chr_22ctg3"]
["D88270","LL22NC03-123E1","Chr_22ctg3"]
["D87003","LL22NC03-2H8","Chr_22ctg3"]
["D87018","LL22NC03-80A10","Chr_22ctg3"]
["D87016","LL22NC03-75A1","Chr_22ctg3"]
["D86999","LL22NC03-22A12","Chr_22ctg3"]
["D87010","LL22NC03-35B9","Chr_22ctg3"]
["D87009","KB288A10","Chr_22ctg3"]
["D87011","LL22NC03-50D10","Chr_22ctg3"]
["D87013","LL22NC03-63E9","Chr_22ctg3"]
["D87014","LL22NC03-61E11","Chr_22ctg3"]
["D86991","LL22NC03-29D3","Chr_22ctg3"]
["D87002","LL22NC03-31F3","Chr_22ctg3"]
["D87006","LL22NC03-52F2","Chr_22ctg3"]
["D86994","LL22NC03-102D1","Chr_22ctg3"]
["D87007","LL22NC03-48A11","Chr_22ctg3"]
["D87015","LL22NC03-68D6","Chr_22ctg3"]
["D86998","LL22NC03-24A12","Chr_22ctg3"]
["D87021","LL22NC03-84E4","Chr_22ctg3"]
["D87024","LL22NC03-92H4","Chr_22ctg3"]
["D87020","LL22NC03-9G6","Chr_22ctg3"]
["D87023","LL22NC03-9C5","Chr_22ctg3"]
["D87017","LL22NC03-75C12","Chr_22ctg3"]
["AP000360","N81C12","Chr_22ctg3"]
["AP000361","N8E4","Chr_22ctg3"]
["AP000362","N75A12","Chr_22ctg3"]
["AC000029",{"v":865000000000,"d":"8.65E+11"},"Chr_22ctg3"]
["AC000102","60b5","Chr_22ctg3"]
["U07000","cos7-1","Chr_22ctg3"]
["AP000343","KB282B12","Chr_22ctg3"]
["AP000344","KB1269D1","Chr_22ctg3"]
["AP000345","KB208E9","Chr_22ctg3"]
["AP000346","KB1572G7","Chr_22ctg3"]
["AP000347","KB113H7","Chr_22ctg3"]
["AP000348","N27C7","Chr_22ctg3"]
["AP000349","KB1839H6","Chr_22ctg3"]
["AP000350","KB1125A3","Chr_22ctg3"]
["AP000351","KB226F1","Chr_22ctg3"]
["AP000352","KB1561E1","Chr_22ctg3"]
["AP000353","KB318B8","Chr_22ctg3"]
["AP000354","KB1674E1","Chr_22ctg3"]
["AP000355","KB1896H10","Chr_22ctg3"]
["AP000356","KB1995A5","Chr_22ctg3"]
["AP000357","N95F10","Chr_22ctg3"]
["AP000358","N110F4","Chr_22ctg3"]
["AP000359","KB63E7","Chr_22ctg3"]
["AL049759","RP5-930L11","Chr_22ctg3"]
["AL050312","RP11-9F11","Chr_22ctg3"]
["AL022323","CTA-243E7","Chr_22ctg3"]
["Z99916","CTA-221G9","Chr_22ctg3"]
["AL022332","RP3-462D8","Chr_22ctg3"]
["AL022324","CTA-246H3","Chr_22ctg3"]
["AL008721","CTA-390C10","Chr_22ctg3"]
["AL022329","CTA-407F11","Chr_22ctg3"]
["AL080245","RP11-89B2","Chr_22ctg3"]
["Z98949","CTA-125H2","Chr_22ctg3"]
["AL079300","CTA-109D1","Chr_22ctg3"]
["AL022337","CTA-796E4","Chr_22ctg3"]
["AL080273","RP11-259P1","Chr_22ctg3"]
["AL023513","RP1-268D13","Chr_22ctg3"]
["AL078460","RP3-341O5","Chr_22ctg3"]
["AL035044","XX-DJ40G4P","Chr_22ctg3"]
["Z99714","CTB-1048E9","Chr_22ctg3"]
["Z95115","CTA-445C9","Chr_22ctg3"]
["Z99774","CTA-373H7","Chr_22ctg3"]
["Z95889","CTA-211A9","Chr_22ctg3"]
["Z97353","RP1-90L6","Chr_22ctg3"]
["AL008638","CTA-992D9","Chr_22ctg3"]
["AL021153","CTA-503F6","Chr_22ctg3"]
["AL034386","RP5-1172A22","Chr_22ctg3"]
["AL020994","CTA-929C8","Chr_22ctg3"]
["AL049536","XX-DJ205F14P","Chr_22ctg3"]
["AL050402","RP11-46E17","Chr_22ctg3"]
["AL133456","XX-DJ231P7P","Chr_22ctg3"]
["AL133397","RP1-213J1p__A","Chr_22ctg3"]
["AL390209","CTA-437G10__A","Chr_22ctg3"]
["AL133398","RP1-213J1p__B","Chr_22ctg3"]
["AL121885","RP11-375H17","Chr_22ctg3"]
["AL390210","CTA-437G10__B","Chr_22ctg3"]
["AL031591","RP3-353E16","Chr_22ctg3"]
["AL033538","RP3-477H23","Chr_22ctg3"]
["AL035453","SC22CB-42E1","Chr_22ctg3"]
["AL050313","CTA-754D9","Chr_22ctg3"]
["AL035397","RP6-45P1","Chr_22ctg3"]
["AL023281","CTA-544A11","Chr_22ctg3"]
["AL008722","CTA-732E4","Chr_22ctg3"]
["AL080241","RP11-541J16","Chr_22ctg3"]
["AL118497","RP11-329J7","Chr_22ctg3"]
["AL121825","RP11-436C9","Chr_22ctg3"]
["AL117330","RP11-444G7","Chr_22ctg3"]
["AL023494","RP3-366L4","Chr_22ctg3"]
["Z93930","CTA-292E10","Chr_22ctg3"]
["AL031596","RP4-745C22","Chr_22ctg3"]
["Z95113","CTA-175E3","Chr_22ctg3"]
["AL021393","CTA-747E2","Chr_22ctg3"]
["Z95116","CTA-57G9","Chr_22ctg3"]
["AL031186","CTA-984G1","Chr_22ctg3"]
["AC000026","58b8","Chr_22ctg3"]
["AC002059","p704f1059q13","Chr_22ctg3"]
["AC000041","p42h1","Chr_22ctg3"]
["AC000035","ll47g11","Chr_22ctg3"]
["AC005529","bk256d12","Chr_22ctg3"]
["AC004882","RP1-76B20","Chr_22ctg3"]
["Z82171","SC22CB-11B7","Chr_22ctg3"]
["AC004819","RP1-15I23","Chr_22ctg3"]
["AC003681","RP3-394A18","Chr_22ctg3"]
["AC003071","CTA-85E5","Chr_22ctg3"]
["AC002378","RP3-438O4","Chr_22ctg3"]
["AC004264","RP1-102K2","Chr_22ctg3"]
["AC004997","RP1-130H16","Chr_22ctg3"]
["AC004832","RP4-539M6","Chr_22ctg3"]
["AC005006","RP1-56J10","Chr_22ctg3"]
["AC003072","CTA-963H5","Chr_22ctg3"]
["AL079299","RP11-492A7","Chr_22ctg3"]
["AL022336","RP1-78F24","Chr_22ctg3"]
["AC004542","RP3-430N8","Chr_22ctg3"]
["AC005233","RP5-1198O21","Chr_22ctg3"]
["AC005005","RP3-412A9","Chr_22ctg3"]
["AC002073","RP3-515N1","Chr_22ctg3"]
["AC005003","RP3-400N23","Chr_22ctg3"]
["AL096702","RP11-254F5","Chr_22ctg3"]
["AL096701","RP11-247I13","Chr_22ctg3"]
["AL109802","RP11-163M1","Chr_22ctg3"]
["AL096768","RP5-858B16","Chr_22ctg3"]
["AL031255","RP4-694E4","Chr_22ctg3"]
["AC005004","RP3-403E2","Chr_22ctg3"]
["AL022331","CTA-440B3","Chr_22ctg3"]
["Z82190","RP1-180M12","Chr_22ctg3"]
["Z83856","LL22NC03-113A11","Chr_22ctg3"]
["Z82248","LL22NC03-44A4","Chr_22ctg3"]
["AL008719","CTA-342B11","Chr_22ctg3"]
["Z74021","SC22CB-1E7","Chr_22ctg3"]
["Z80998","SC22CB-36G12","Chr_22ctg3"]
["Z83849","CITF22-65B7","Chr_22ctg3"]
["AL022321","RP1-20O8","Chr_22ctg3"]
["Z83839","RP1-127L4","Chr_22ctg3"]
["AL008723","RP1-90G24","Chr_22ctg3"]
["AL021937","RP1-149A16","Chr_22ctg3"]
["AL035068","RP1-116G19","Chr_22ctg3"]
["Z71183","LL22NC03-28H9","Chr_22ctg3"]
["Z82181","LL22NC01-86D10","Chr_22ctg3"]
["Z80902","LL22NC03-80H12","Chr_22ctg3"]
["AL021452","CTA-285F3","Chr_22ctg3"]
["Z82246","LL22NC03-104C7","Chr_22ctg3"]
["Z75744","LL22NC03-117B5","Chr_22ctg3"]
["Z81309","LL22NC01-92H8","Chr_22ctg3"]
["Z69714","LL22NC03-37F10","Chr_22ctg3"]
["Z72521","LL22NC03-29F4","Chr_22ctg3"]
["Z72520","LL22NC03-19H5","Chr_22ctg3"]
["Z73495","LL22NC01-116C6","Chr_22ctg3"]
["AL023282","CTA-766E1","Chr_22ctg3"]
["Z73979","SC22CB-10B1","Chr_22ctg3"]
["Z98256","RP1-309I22","Chr_22ctg3"]
["AL031592","CTA-366B10","Chr_22ctg3"]
["Z83846","CTA-415G2","Chr_22ctg3"]
["Z82198","RP1-302D9","Chr_22ctg3"]
["AL008630","CTA-282F2","Chr_22ctg3"]
["Z82173","SC22CB-1D7","Chr_22ctg3"]
["AL008715","CTC-1216H12","Chr_22ctg3"]
["AL023577","CTA-566G5","Chr_22ctg3"]
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