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["feature","gene name","peak time","chr","strand","start","stop","length","category","function"]
["YKL116C","PRR1",0,11,"-",221016,222616,1601,"ORF Verified","Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor"]
["YKL164C","PIR1",0,11,"-",141776,142856,1081,"ORF Verified","O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle"]
["YLR079W","SIC1",0,12,"+",286785,287761,977,"ORF Verified","Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1"]
["YNL078W","NIS1",0,14,"+",479737,481089,1353,"ORF Verified","Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network"]
["YNL327W","EGT2",0,14,"+",24065,27105,3041,"ORF Verified","Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner"]
["YIL009W","FAA3",1,9,"+",339305,341345,2041,"ORF Verified","Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery"]
["YER158C",null,2,5,"-",487972,488877,906,"ORF Uncharacterized","Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p"]
["YNR067C","DSE4",2,14,"-",755782,759134,3353,"ORF Verified","Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother"]
["YOL011W","PLB3",2,15,"+",304593,307617,3025,"ORF Verified","Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro"]
["YOR264W","DSE3",2,15,"+",818817,820089,1273,"ORF Verified","Daughter cell-specific protein, may help establish daughter fate"]
["YBR067C","TIP1",3,2,"-",372067,372787,721,"ORF Verified","Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p%2FTip1p family of serine-alanine-rich proteins"]
["YBR158W","AMN1",3,2,"+",556264,558320,2057,"ORF Verified","Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)"]
["YDR055W","PST1",3,4,"+",563458,564850,1393,"ORF Verified","Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1"]
["YEL066W","HPA3",3,5,"+",26689,27049,361,"ORF Verified","D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro"]
["YGR044C","RME1",3,7,"-",583175,583967,793,"ORF Verified","Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-a2 regulator; mediates cell type control of sporulation"]
["YGR062C","COX18",3,7,"-",616327,617271,945,"ORF Verified","Mitochondrial inner membrane protein, required for export of the Cox2p C terminus from the mitochondrial matrix to the intermembrane space during its assembly into cytochrome c oxidase; similar to Oxa2p of N. crassa"]
["YJL218W",null,3,10,"+",21969,22505,537,"ORF Uncharacterized","Putative protein of unknown function, similar to bacterial galactoside O-acetyltransferases; induced by oleate in an OAF1/PIP2-dependent manner; promoter contains an oleate response element consensus sequence; non-essential gene"]
["YNL173C","MDG1",3,14,"-",309093,310069,977,"ORF Verified","Plasma membrane protein involved in G-protein mediated pheromone signaling pathway; overproduction suppresses bem1 mutations"]
["YCR098C","GIT1",4,3,"-",298525,300677,2153,"ORF Verified","Plasma membrane permease, mediates uptake of the phosphatidylinositol metabolite glycerophosphoinositol as a source of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability"]
["YNL192W","CHS1",4,14,"+",276473,279505,3033,"ORF Verified","Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for repairing the chitin septum during cytokinesis; transcription activated by mating factor"]
["YOL006C","TOP1",4,15,"-",313525,314933,1409,"ORF Verified","Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination"]
["YOL159C-A",null,4,15,"-",14725,15517,793,"ORF Uncharacterized","Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species"]
["YOR342C",null,4,15,"-",966589,967717,1129,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus"]
["YGR289C","MAL11",5,7,"-",1074070,1076086,2017,"ORF Verified","Maltose permease, inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters"]
["YLR194C",null,5,12,"-",540789,541573,785,"ORF Uncharacterized","Structural constituent of the cell wall attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress"]
["YMR251W-A","HOR7",5,13,"+",774721,775105,385,"ORF Verified","Protein of unknown function; overexpression suppresses Ca2+ sensitivity of mutants lacking inositol phosphorylceramide mannosyltransferases Csg1p and Csh1p; transcription is induced under hyperosmotic stress and repressed by alpha factor"]
["YGL055W","OLE1",6,7,"+",398579,399755,1177,"ORF Verified","Fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria"]
["YLR049C",null,6,12,"-",243781,245221,1441,"ORF Uncharacterized","Putative protein of unknown function"]
["YIL159W","BNR1",7,9,"+",41977,44121,2145,"ORF Verified","Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNI1"]
["YOR374W","ALD4",7,15,"+",1039833,1041257,1425,"ORF Verified","Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed"]
["YBR071W",null,8,2,"+",380351,381271,921,"ORF Uncharacterized","Putative protein of unknown function; (GFP)-fusion and epitope-tagged proteins localize to the cytoplasm; mRNA expression may be regulated by the cell cycle and/or cell wall stress"]
["YER111C","SWI4",8,5,"-",383733,385565,1833,"ORF Verified","DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair"]
["YKL163W","PIR3",8,11,"+",143604,144420,817,"ORF Verified","O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway"]
["YOR347C","PYK2",8,15,"-",985125,986533,1409,"ORF Verified","Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by glucose, and Pyk2p may be active under low glycolytic flux"]
["YDL102W","POL3",9,4,"+",276793,280185,3393,"ORF Verified","Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER)"]
["YKR077W",null,9,11,"+",583244,584172,929,"ORF Uncharacterized","Putative transcriptional activator, identified by high-throughput two-hybrid experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YKR077W is not an essential gene"]
["YPR018W","RLF2",9,16,"+",594363,596291,1929,"ORF Verified","Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin"]
["YDR309C","GIC2",10,4,"-",1079039,1080263,1225,"ORF Verified","Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain"]
["YGL028C","SCW11",10,7,"-",441583,443087,1505,"ORF Verified","Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p"]
["YHR149C","SKG6",10,8,"-",395493,396797,1305,"ORF Verified","Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p"]
["YHR189W","PTH1",10,8,"+",484027,484795,769,"ORF Verified","One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases; dispensable for cell growth and for mitochondrial respiration"]
["YJL217W",null,10,10,"+",23129,23561,433,"ORF Uncharacterized","hypothetical protein "]
["YLR457C","NBP1",10,12,"-",1053163,1055891,2729,"ORF Verified","Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuclear membrane during SPB duplication; essential for bipolar spindle formation; component of the Mps2p-Bbp1p complex"]
["YNL310C","ZIM17",10,14,"-",51813,52461,649,"ORF Verified","Heat shock protein with a zinc finger motif; essential for protein import into mitochondria; may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix"]
["YDL022W","GPD1",11,4,"+",411785,412961,1177,"ORF Verified","NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p"]
["YDL103C","QRI1",11,4,"-",275237,276637,1401,"ORF Verified","UDP-N-acetylglucosamine pyrophosphorylase, catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis"]
["YDL127W","PCL2",11,4,"+",234873,235769,897,"ORF Verified","G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to entry into the mitotic cell cycle, essential for cell morphogenesis; localizes to sites of polarized cell growth"]
["YDL156W",null,11,4,"+",174841,175953,1113,"ORF Uncharacterized","Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus"]
["YDR279W","RNH202",11,4,"+",1019267,1020243,977,"ORF Verified","Ribonuclease H2 subunit, required for RNase H2 activity"]
["YDR528W","HLR1",11,4,"+",1494299,1495891,1593,"ORF Verified","Protein involved in regulation of cell wall composition and integrity and response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; similar to Lre1p, which functions antagonistically to protein kinase A"]
["YGL037C","PNC1",11,7,"-",427199,427447,249,"ORF Verified","Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span"]
["YGR238C","KEL2",11,7,"-",966086,968654,2569,"ORF Verified","Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate"]
["YJL196C","ELO1",11,10,"-",67869,68813,945,"ORF Verified","Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids"]
["YJR043C","POL32",11,10,"-",516437,517453,1017,"ORF Verified","Third subunit of DNA polymerase delta, involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; interacts with Hys2p, PCNA (Pol30p), and Pol1p"]
["YNL274C","GOR1",11,14,"-",121325,122221,897,"ORF Verified","Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies"]
["YPL014W",null,11,16,"+",527531,528611,1081,"ORF Uncharacterized","uncharacterized ORF"]
["YBL010C",null,12,2,"-",205972,206972,1001,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein colocalizes with clathrin-coated vesicles"]
["YDL105W","NSE4",12,4,"+",272385,273665,1281,"ORF Verified","Nuclear protein that plays a role in the function of the Smc5p-Rhc18p complex"]
["YFR027W","ECO1",12,6,"+",207409,208313,905,"ORF Verified","Acetyltransferase required for the establishment of sister chromatid cohesion during DNA replication, but not for its maintenance during G2 and M phases; also required for postreplicative double-strand break repair; interacts with Chl1p"]
["YGL207W","SPT16",12,7,"+",98899,102059,3161,"ORF Verified","Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure"]
["YGR041W","BUD9",12,7,"+",577179,578859,1681,"ORF Verified","Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the distal pole"]
["YJR057W","CDC8",12,10,"+",543977,544425,449,"ORF Verified","Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p"]
["YKL045W","PRI2",12,11,"+",353548,354396,849,"ORF Verified","Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair"]
["YKL108W","SLD2",12,11,"+",234060,235324,1265,"ORF Verified","Protein required for DNA replication, phosphorylated in S phase by S-phase cyclin-dependent kinases (Cdks), phosphorylation is essential for DNA replication and for complex formation with Dpb11p; potential Cdc28p substrate"]
["YLR233C","EST1",12,12,"-",607461,609549,2089,"ORF Verified","TLC1 RNA-associated factor involved in telomere length regulation as the recruitment subunit of the telomerase holoenzyme, has a possible role in activating Est2p-TLC1-RNA bound to the telomere"]
["YMR179W","SPT21",12,13,"+",620449,622217,1769,"ORF Verified","Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; functionally related to Spt10p; involved in telomere maintenance"]
["YNL082W","PMS1",12,14,"+",473385,475993,2609,"ORF Verified","ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL"]
["YNL309W","STB1",12,14,"+",52617,53977,1361,"ORF Verified","Protein with a role in regulation of MBF-specific transcription at Start, phosphorylated by Cln-Cdc28p kinases in vitro; unphosphorylated form binds Swi6p and binding is required for Stb1p function; expression is cell-cycle regulated"]
["YOR144C","ELG1",12,15,"-",603069,605101,2033,"ORF Verified","Protein required for S phase progression and telomere homeostasis, forms an alternative replication factor C complex important for DNA replication and genome integrity; involved in homologous recombination-mediated DNA repair"]
["YBL035C","POL12",13,2,"-",151523,153075,1553,"ORF Verified","B subunit of DNA polymerase alpha-primase complex, required for initiation of DNA replication during mitotic and premeiotic DNA synthesis; also functions in telomere capping and length regulation"]
["YBR098W","MMS4",13,2,"+",441495,443495,2001,"ORF Verified","Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination and DNA repair"]
["YCL024W","KCC4",13,3,"+",81913,82265,353,"ORF Verified","Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p"]
["YDL227C","HO",13,4,"-",46285,48061,1777,"ORF Verified","Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p"]
["YDR440W","DOT1",13,4,"+",1342395,1344251,1857,"ORF Verified","Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active genes, functions in gene silencing at telomeres, most likely by directly modulating chromatin structure and Sir protein localization"]
["YGR109C","CLB6",13,7,"-",705319,706575,1257,"ORF Verified","B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1"]
["YGR151C",null,13,7,"-",793095,794719,1625,"ORF Dubious","hypothetical protein imeediately 5' of or overlapping of RSR1"]
["YGR152C","RSR1",13,7,"-",793095,794719,1625,"ORF Verified","GTP-binding protein of the ras superfamily required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases "]
["YJL181W",null,13,10,"+",86113,87441,1329,"ORF Uncharacterized","Putative protein of unknown function; expression is cell-cycle regulated as shown by microarray analysis"]
["YLR032W","RAD5",13,12,"+",205001,208513,3513,"ORF Verified","Single-stranded DNA-dependent ATPase, involved in postreplication repair; contains RING finger domain"]
["YLR382C","NAM2",13,12,"-",882203,884787,2585,"ORF Verified","Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance"]
["YML020W",null,13,13,"+",231017,233265,2249,"ORF Uncharacterized","Putative protein of unknown function"]
["YML102W","CAC2",13,13,"+",68281,69745,1465,"ORF Verified","Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans"]
["YNL273W","TOF1",13,14,"+",122841,126233,3393,"ORF Verified","Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase"]
["YNL304W","YPT11",13,14,"+",60257,61633,1377,"ORF Verified","Rab-type small GTPase that interacts with the C-terminal tail domain of Myo2p to mediate distribution of mitochondria to daughter cells"]
["YOR033C","EXO1",13,15,"-",392829,394629,1801,"ORF Verified","5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains"]
["YPL221W","FLC1",13,16,"+",132801,135057,2257,"ORF Verified","Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance"]
["YPR175W","DPB2",13,16,"+",888955,891003,2049,"ORF Verified","Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required for normal yeast chromosomal replication; expression peaks at the G1/S phase boundary; potential Cdc28p substrate"]
["YAR003W","SWD1",14,1,"+",154943,156463,1521,"ORF Verified","Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7"]
["YAR008W","SEN34",14,1,"+",158879,159847,969,"ORF Verified","Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease"]
["YDL164C","CDC9",14,4,"-",164869,167293,2425,"ORF Verified","DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination"]
["YDR481C","PHO8",14,4,"-",1418439,1420279,1841,"ORF Verified","Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides"]
["YER153C","PET122",14,5,"-",474101,474765,665,"ORF Verified","Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet54p and Pet494p; located in the mitochondrial inner membrane"]
["YFR026C",null,14,6,"-",205869,207197,1329,"ORF Uncharacterized","Putative protein of unknown function"]
["YHR159W",null,14,8,"+",417489,420017,2529,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; potential Cdc28p substrate"]
["YIL101C","XBP1",14,9,"-",176269,177421,1153,"ORF Verified","Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate"]
["YJL074C","SMC3",14,10,"-",299125,302781,3657,"ORF Verified","Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member"]
["YJL078C","PRY3",14,10,"-",293661,293989,329,"ORF Verified","Protein of unknown function, has similarity to Pry1p and Pry2p and to the plant PR-1 class of pathogen related proteins"]
["YNL233W","BNI4",14,14,"+",211753,214521,2769,"ORF Verified","Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p"]
["YPR120C","CLB5",14,16,"-",773903,775287,1385,"ORF Verified","B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase"]
["YPR174C",null,14,16,"-",887863,888727,865,"ORF Uncharacterized","Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery; potential Cdc28p substrate"]
["YPR184W","GDB1",14,16,"+",902043,904195,2153,"ORF Verified","Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation; phosphorylated in mitochondria"]
["YDR097C","MSH6",15,4,"-",640174,643862,3689,"ORF Verified","Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p"]
["YER124C","DSE1",15,5,"-",407941,409093,1153,"ORF Verified","Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall"]
["YGL126W","SCS3",15,7,"+",270947,272235,1289,"ORF Verified","Protein required for inositol prototrophy, appears to be involved in the synthesis of inositol phospholipids from inositol but not in the control of inositol synthesis"]
["YJL115W","ASF1",15,10,"+",196137,196913,777,"ORF Verified","Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed"]
["YJR030C",null,15,10,"-",484045,485693,1649,"ORF Uncharacterized","Putative protein of unknown function; expression repressed in carbon limited vs carbon replete chemostat cultures; YJR030C is a non-essential gene"]
["YJR154W",null,15,10,"+",725473,726977,1505,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm"]
["YJR155W","AAD10",15,10,"+",726985,727881,897,"ORF Verified","Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role"]
["YLL002W","RTT109",15,12,"+",146273,147553,1281,"ORF Verified","Histone acetyltransferase critical for cell survival in the presence of DNA damage during S phase, acetylates H3-K56; plays a role in regulation of Ty1 transposition"]
["YLR212C","TUB4",15,12,"-",564757,566285,1529,"ORF Verified","Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body"]
["YMR011W","HXT2",15,13,"+",288065,289561,1497,"ORF Verified","High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose"]
["YNL015W","PBI2",15,14,"+",605298,605722,425,"ORF Verified","Cytosolic inhibitor of vacuolar proteinase B, required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion"]
["YNL077W","APJ1",15,14,"+",481289,482833,1545,"ORF Verified","Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies"]
["YNL262W","POL2",15,14,"+",148209,151657,3449,"ORF Verified","Catalytic subunit of DNA polymerase (II) epsilon, one of the major chromosomal DNA replication polymerases characterized by processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair"]
["YOR284W","HUA2",15,15,"+",848433,849377,945,"ORF Verified","Cytoplasmic protein of unknown function; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly"]
["YPL267W","ACM1",15,16,"+",38169,38785,617,"ORF Verified","Cell cycle regulated protein of unknown function; associated with Cdh1p and may supress the APC/C[Cdh1]-mediated proteolysis of mitotic cyclins"]
["YPR135W","CTF4",15,16,"+",800235,802035,1801,"ORF Verified","Chromatin-associated protein, required for sister chromatid cohesion; interacts with DNA polymerase alpha (Pol1p) and may link DNA synthesis to sister chromatid cohesion"]
["YAR007C","RFA1",16,1,"-",156939,158675,1737,"ORF Verified","Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination"]
["YBR073W","RDH54",16,2,"+",383143,385991,2849,"ORF Verified","DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference"]
["YCL061C","MRC1",16,3,"-",18725,22141,3417,"ORF Verified","S-phase checkpoint protein found at replication forks, required for DNA replication; also required for Rad53p activation during DNA replication stress, where it forms a replication-pausing complex with Tof1p and is phosphorylated by Mec1p"]
["YDR307W",null,16,4,"+",1076003,1077379,1377,"ORF Uncharacterized","Putative protein of unknown function"]
["YER170W","ADK2",16,{"$nulls":5},"ORF Verified","Mitochondrial adenylate kinase, catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background"]
["YFL008W","SMC1",16,6,"+",120993,123129,2137,"ORF Verified","Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure"]
["YFL054C",null,16,6,"-",20901,22821,1921,"ORF Uncharacterized","Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol"]
["YGL038C","OCH1",16,7,"-",425111,426815,1705,"ORF Verified","Mannosyltransferase of the cis-Golgi apparatus, initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins"]
["YGL089C","MF",16,7,"-",344695,345199,505,"ORF Verified","Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)1, which is more highly expressed than MF(ALPHA)2"]
["YLR103C","CDC45",16,12,"-",345581,346005,425,"ORF Verified","DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes"]
["YLR120C","YPS1",16,12,"-",386197,388325,2129,"ORF Verified","Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor"]
["YLR286C","CTS1",16,12,"-",708357,710365,2009,"ORF Verified","Endochitinase, required for cell separation after mitosis; transcriptional activation during late G and early M cell cycle phases is mediated by transcription factor Ace2p"]
["YLR312C-B",null,16,12,"-",760413,762267,1855,"ORF Verified","5' of or overlapping SPH1Protein involved in shmoo formation and bipolar bud site selection; homologous to Spa2p, localizes to sites of polarized growth in a cell cycle dependent- and Spa2p-dependent manner, interacts with MAPKKs Mkk1p, Mkk2p, and Ste7p "]
["YLR313C","SPH1",16,12,"-",760413,762267,1855,"ORF Verified","Protein involved in shmoo formation and bipolar bud site selection; homologous to Spa2p, localizes to sites of polarized growth in a cell cycle dependent- and Spa2p-dependent manner, interacts with MAPKKs Mkk1p, Mkk2p, and Ste7p"]
["YMR048W","CSM3",16,13,"+",366977,367921,945,"ORF Verified","Protein required for accurate chromosome segregation during meiosis"]
["YNL102W","POL1",16,14,"+",430417,432769,2353,"ORF Verified","Catalytic subunit of the DNA polymerase I alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis"]
["YOL017W","ESC8",16,15,"+",292553,294505,1953,"ORF Verified","Protein involved in telomeric and mating-type locus silencing, interacts with Sir2p and also interacts with the Gal11p, which is a component of the RNA pol II mediator complex"]
["YOR288C","MPD1",16,15,"-",852213,853133,921,"ORF Verified","Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone activity of Cne1p; MPD1 overexpression in a pdi1 null mutant suppresses defects in Pdi1p functions such as carboxypeptidase Y maturation"]
["YOR368W","RAD17",16,15,"+",1026849,1027929,1081,"ORF Verified","Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins"]
["YPL153C","RAD53",16,16,"-",261693,264325,2633,"ORF Verified","Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication"]
["YBR088C","POL30",17,2,"-",425003,425811,809,"ORF Verified","Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair"]
["YCL027W","FUS1",17,3,"+",71761,72985,1225,"ORF Verified","Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate"]
["YDL003W","MCD1",17,4,"+",444561,446161,1601,"ORF Verified","Essential protein required for sister chromatid cohesion in mitosis and meiosis; subunit of the cohesin complex; expression is cell cycle regulated and peaks in S phase"]
["YDR507C","GIN4",17,4,"-",1462791,1465887,3097,"ORF Verified","Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Kcc4p and Hsl1p"]
["YDR517W","GRH1",17,4,"+",1478107,1478443,337,"ORF Verified","Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes"]
["YER070W","RNR1",17,5,"+",298881,301489,2609,"ORF Verified","Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits"]
["YER152C",null,17,5,"-",472605,474093,1489,"ORF Uncharacterized","Putative protein of unknown function; shares amino acid similarity with the aminotransferases Aro8p and Aro9p; YER152C is not an essential gene"]
["YJL073W","JEM1",17,10,"+",303009,304105,1097,"ORF Verified","DnaJ-like chaperone required for nuclear membrane fusion during mating, localizes to the ER membrane; exhibits genetic interactions with KAR2"]
["YKL113C","RAD27",17,11,"-",224432,225560,1129,"ORF Verified","5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family"]
["YOL090W","MSH2",17,15,"+",147345,150017,2673,"ORF Verified","Protein that forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity; Msh2p-Msh6p binds to and hydrolyzes ATP"]
["YBR070C","ALG14",18,2,"-",379227,379971,745,"ORF Verified","Component of UDP-GlcNAc transferase required for the second step of dolichyl-linked oligosaccharide synthesis; anchors the catalytic subunit Alg13p to the ER membrane; similar to bacterial and human glycosyltransferases"]
["YDL018C","ERP3",18,4,"-",423013,423565,553,"ORF Verified","Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport"]
["YEL064C","AVT2",18,5,"-",29973,31253,1281,"ORF Verified","Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters"]
["YGR221C","TOS2",18,7,"-",937311,938463,1153,"ORF Verified","Protein involved in localization of Cdc24p to the site of bud growth; may act as a membrane anchor; localizes to the bud neck and bud tip; potentially phosphorylated by Cdc28p"]
["YHR127W",null,18,8,"+",360880,361840,961,"ORF Verified","Protein of unknown function; localizes to the nucleus"]
["YHR153C","SPO16",18,8,"-",401557,402677,1121,"ORF Verified","Protein of unknown function, required for spore formation"]
["YIL026C","IRR1",18,9,"-",304485,307229,2745,"ORF Verified","Subunit of the cohesin complex, which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms, essential for viability"]
["YLR121C","YPS3",18,12,"-",388757,390285,1529,"ORF Verified","Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor"]
["YLR234W","TOP3",18,12,"+",609737,612297,2561,"ORF Verified","DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination"]
["YLR386W","VAC14",18,12,"+",894183,896367,2185,"ORF Verified","Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p"]
["YML027W","YOX1",18,13,"+",221329,222641,1313,"ORF Verified","Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate"]
["YML060W","OGG1",18,13,"+",151809,152841,1033,"ORF Verified","Mitochondrial glycosylase/lyase that specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA"]
["YPL057C","SUR1",18,16,"-",451471,453223,1753,"ORF Verified","Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p"]
["YPL255W","BBP1",18,16,"+",67681,68945,1265,"ORF Verified","Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p"]
["YBR275C","RIF1",19,2,"-",753900,757212,3313,"ORF Verified","Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation"]
["YCL040W","GLK1",19,3,"+",50785,52217,1433,"ORF Verified","Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources"]
["YCR065W","HCM1",19,3,"+",229801,231145,1345,"ORF Verified","Forkhead transcription factor that drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role"]
["YDR400W","URH1",19,4,"+",1270995,1271683,689,"ORF Verified","Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in recycling pyrimidine deoxy- and ribonucleosides via the pyrimidine salvage pathway"]
["YDR503C","LPP1",19,4,"-",1454951,1455895,945,"ORF Verified","Lipid phosphate phosphatase, catalyzes Mg(2+)-independent dephosphorylation of phosphatidic acid (PA), lysophosphatidic acid, and diacylglycerol pyrophosphate; involved in control of the cellular levels of phosphatidylinositol and PA"]
["YER095W","RAD51",19,5,"+",349921,351377,1457,"ORF Verified","Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein"]
["YGR153W",null,19,7,"+",796083,796603,521,"ORF Uncharacterized","Putative protein of unknown function"]
["YHR143W","DSE2",19,8,"+",385249,386529,1281,"ORF Verified","Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP"]
["YHR188C","GPI16",19,8,"-",482439,483871,1433,"ORF Verified","Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Tp homolog"]
["YJL019W","MPS3",19,10,"+",403561,407201,3641,"ORF Verified","Essential integral membrane protein required for spindle pole body duplication and for nuclear fusion, localizes to the spindle pole body half bridge, interacts with DnaJ-like chaperone Jem1p and with centrin homolog Cdc31p"]
["YJR054W",null,19,10,"+",535945,537321,1377,"ORF Uncharacterized","Vacuolar protein of unknown function; potential Cdc28p substrate"]
["YLL022C","HIF1",19,12,"-",99117,100189,1073,"ORF Verified","Non-essential component of the HAT-B histone acetyltransferase complex (Hat1p-Hat2p-Hif1p), localized to the nucleus; has a role in telomeric silencing"]
["YLR183C","TOS4",19,12,"-",520469,522077,1609,"ORF Verified","Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF"]
["YNL072W","RNH201",19,14,"+",490305,491145,841,"ORF Verified","Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis; cooperates with Rad27p nuclease"]
["YNL312W","RFA2 ",19,14,"+",48417,49289,873,"ORF Verified"," Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination"]
["YOL019W",null,19,15,"+",289441,290521,1081,"ORF Uncharacterized","Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole"]
["YDR348C",null,20,4,"-",1170263,1172039,1777,"ORF Uncharacterized","Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud neck; potential Cdc28p substrate"]
["YJL091C","GWT1",20,10,"-",261317,262469,1153,"ORF Verified","Protein involved in the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) to form glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors"]
["YKL042W","SPC42",20,11,"+",357988,359340,1353,"ORF Verified","Central plaque component of spindle pole body (SPB); involved in SPB duplication, may facilitate attachment of the SPB to the nuclear membrane"]
["YML021C","UNG1",20,13,"-",229701,230781,1081,"ORF Verified","Uracil-DNA glycosylase, required for repair of uracil in DNA formed by spontaneous cytosine deamination, not required for strand-specific mismatch repair, cell-cycle regulated, expressed in late G1, localizes to mitochondria and nucleus"]
["YMR076C","PDS5",20,13,"-",416197,419261,3065,"ORF Verified","Protein required for establishment and maintenance of sister chromatid condensation and cohesion, colocalizes with cohesin on chromosomes in an interdependent manner, may function as a protein-protein interaction scaffold"]
["YNL289W","PCL1",20,14,"+",87825,88801,977,"ORF Verified","Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth"]
["YOR074C","CDC21",20,15,"-",466637,467629,993,"ORF Verified","Thymidylate synthase, required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1%2FS"]
["YPL208W","RKM1",20,16,"+",157833,159129,1297,"ORF Verified","SET-domain lysine-N-methyltransferase, catalyzes the formation of dimethyllysine residues on the large ribsomal subunit protein L23a (RPL23A and RPL23B)"]
["YPL241C","CIN2",20,16,"-",95437,96037,601,"ORF Verified","Tubulin folding factor C (putative) involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl"]
["YPL256C","CLN2",20,16,"-",64773,66781,2009,"ORF Verified","G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)"]
["YBR042C","CST26",21,2,"-",320668,321652,985,"ORF Verified","Protein of unknown function, affects chromosome stability when overexpressed"]
["YDL010W",null,21,4,"+",432329,433009,681,"ORF Uncharacterized","Putative thiol oxidoreductase; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; non-essential gene"]
["YDL197C","ASF2",21,4,"-",104781,106477,1697,"ORF Verified","Anti-silencing protein that causes derepression of silent loci when overexpressed"]
["YDL211C",null,21,4,"-",79317,80469,1153,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole"]
["YER104W","RTT105",21,5,"+",366785,367745,961,"ORF Verified","Protein with a role in regulation of Ty1 transposition"]
["YGR189C","CRH1",21,7,"-",876615,878287,1673,"ORF Verified","Cell wall protein that functions in the transfer of chitin to beta(1-6)glucan, putative chitin transglycosidase"]
["YHR154W","RTT107",21,8,"+",402929,405313,2385,"ORF Verified","Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition"]
["YIL140W","AXL2",21,9,"+",86289,87689,1401,"ORF Verified","Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate"]
["YIL141W",null,21,9,"+",85233,86281,1049,"ORF Dubious","3' region of AXL2 (Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate),  overlapping TFBSs"]
["YJL187C","SWE1",21,10,"-",76829,79333,2505,"ORF Verified","Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate"]
["YMR078C","CTF18",21,13,"-",422445,424733,2289,"ORF Verified","Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint"]
["YMR199W","CLN1",21,13,"+",662449,664393,1945,"ORF Verified","G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)"]
["YNL055C","POR1",21,14,"-",517934,518910,977,"ORF Verified","Mitochondrial porin (voltage-dependent anion channel), outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability; phosphorylated"]
["YNL165W",null,21,14,"+",323769,325137,1369,"ORF Uncharacterized","Putative protein of unknown function; YNL165W is not an essential gene"]
["YOL007C","CSI2",21,15,"-",311061,312445,1385,"ORF Verified","Protein of unknown function; green fluorescent protein (GFP)- fusion protein localizes to the mother side of the bud neck and the vacuole; YOL007C is not an essential gene"]
["YOR114W",null,21,15,"+",537473,538433,961,"ORF Uncharacterized","Hypothetical protein"]
["YOR176W","HEM15",21,15,"+",662305,663593,1289,"ORF Verified","Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway"]
["YOR321W","PMT3",21,15,"+",915985,918313,2329,"ORF Verified","Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt5p, can instead interact with Pmt1p in some conditions; target for new antifungals"]
["YHR110W","ERP5",22,8,"+",332264,332672,409,"ORF Verified","Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport"]
["YIL132C","CSM2",22,9,"-",99453,100501,1049,"ORF Verified","Protein required for accurate chromosome segregation during meiosis"]
["YKL089W","MIF2",22,11,"+",273012,274276,1265,"ORF Verified","Kinetochore protein with homology to human CENP-C, required for structural integrity of the spindle during anaphase spindle elongation, interacts with histones H2A, H2B, and H4, phosphorylated by Ipl1p"]
["YKL092C","BUD2",22,11,"-",265824,267880,2057,"ORF Verified","GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types"]
["YKL165C","MCD4",22,11,"-",139184,140760,1577,"ORF Verified","Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; multimembrane-spanning protein that localizes to the endoplasmic reticulum; highly conserved among eukaryotes"]
["YML100W","TSL1",22,13,"+",73713,74017,305,"ORF Verified","Large subunit of trehalose 6-phosphate synthase (Tps1p)/phosphatase (Tps2p) complex, which converts uridine-5'-diphosphoglucose and glucose 6-phosphate to trehalose, homologous to Tps3p and may share function"]
["YPL124W","SPC29",22,16,"+",316737,317513,777,"ORF Verified","Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inner plaque component Spc110p; required for SPB duplication"]
["YBR161W","CSH1",23,2,"+",561488,562832,1345,"ORF Verified","Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p"]
["YDL101C","DUN1",23,4,"-",280181,281845,1665,"ORF Verified","Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair"]
["YDR518W","EUG1",23,4,"+",1478563,1479699,1137,"ORF Verified","Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER"]
["YGL027C","CWH41",23,7,"-",443919,446167,2249,"ORF Verified","Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress"]
["YJL173C","RFA3",23,10,"-",96109,96533,425,"ORF Verified","Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination"]
["YJR116W",null,23,10,"+",640609,641697,1089,"ORF Uncharacterized","Putative protein of unknown function"]
["YLR383W","SMC6",23,12,"+",885215,888695,3481,"ORF Verified","Protein involved in structural maintenance of chromosomes; essential subunit of Mms21-Smc5-Smc6 complex; required for growth, DNA repair, interchromosomal and sister chromatid recombination; homologous to S. pombe rad18"]
["YNL263C","YIF1",23,14,"-",147045,147973,929,"ORF Verified","Integral membrane protein required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles"]
["YOR008C","SLG1",23,15,"-",341293,342461,1169,"ORF Verified","Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in maintenance of cell wall integrity; involved in organization of the actin cytoskeleton; secretory pathway Wsc1p is required for the arrest of secretion response"]
["YEL047C",null,24,5,"-",65829,66813,985,"ORF Verified","Soluble fumarate reductase, required with isoenzyme Osm1p for anaerobic growth; may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies"]
["YKL101W","HSL1",24,11,"+",249684,252740,3057,"ORF Verified","Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p"]
["YKR013W","PRY2",24,11,"+",463604,464196,593,"ORF Verified","Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins"]
["YLR042C",null,24,12,"-",230029,230501,473,"ORF Uncharacterized","Protein of unknown function; localizes to the cytoplasm; YLL042C is not an essential gene"]
["YML061C","PIF1",24,13,"-",148909,151661,2753,"ORF Verified","DNA helicase involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; also plays a role in repair and recombination of mitochondrial DNA"]
["YDL093W","PMT5",25,4,"+",289873,292313,2441,"ORF Verified","Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt3p, can instead interact with Pmt2p in some conditions; target for new antifungals"]
["YFL052W",null,25,6,"+",28233,31617,3385,"ORF Uncharacterized","Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity"]
["YGL175C","SAE2",25,{"$nulls":5},"ORF Verified","Protein with a role in accurate meiotic and mitotic double-strand break repair; phosphorylated in response to DNA damage and required for normal resistance to DNA-damaging agents"]
["YLR151C","PCD1",25,12,"-",441725,442725,1001,"ORF Verified","Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids"]
["YLR381W","CTF3",25,12,"+",879687,881679,1993,"ORF Verified","Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to spindle microtubules"]
["YPL163C","SVS1",25,16,"-",241765,242733,969,"ORF Verified","Cell wall and vacuolar protein, required for wild-type resistance to vanadate"]
["YAL034W-A","MTW1",26,1,"+",79719,80519,801,"ORF Verified","Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly"]
["YAL053W","FLC2",26,1,"+",45761,48305,2538,"ORF Verified","Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance"]
["YDR263C","DIN7",26,4,"-",994159,995759,1601,"ORF Verified","Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination"]
["YDR501W","PLM2",26,4,"+",1451299,1452971,1673,"ORF Verified","Protein required for partitioning of the 2-micron plasmid"]
["YER001W","MNN1",26,5,"+",153473,155769,2297,"ORF Verified","Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family"]
["YFR053C","HXK1",26,6,"-",253485,255133,1649,"ORF Verified","Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p"]
["YKL067W","YNK1",26,11,"+",314348,315108,761,"ORF Verified","Nucleoside diphosphate kinase, catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate"]
["YLR050C",null,26,12,"-",245629,246141,513,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR050C is not an essential gene"]
["YNL300W",null,26,14,"+",65665,66281,617,"ORF Uncharacterized","Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid"]
["YPR183W","DPM1",26,16,"+",900723,901619,897,"ORF Verified","Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation"]
["YGL061C","DUO1",27,7,"-",389039,389775,737,"ORF Verified","Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis"]
["YJL042W","MHP1",27,10,"+",361097,364865,3769,"ORF Verified","Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins"]
["YBR241C",null,28,2,"-",703036,704108,1073,"ORF Uncharacterized","Putative transporter, member of the sugar porter family; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane; YBR241C is not an essential gene"]
["YER118C","SHO1",28,5,"-",398005,399221,1217,"ORF Verified","Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway"]
["YGL094C","PAN2",28,7,"-",331167,334639,3473,"ORF Verified","Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes"]
["YLR343W","GAS2",28,12,"+",815903,817695,1793,"ORF Verified","Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p"]
["YOR195W","SLK19",28,15,"+",712809,714689,1881,"ORF Verified","Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate"]
["YPR075C","OPY2",28,16,"-",695823,696863,1041,"ORF Verified","Integral membrane protein that functions in the signaling branch of the high-osmolarity glycerol (HOG) pathway; interacts with Ste50p; overproduction blocks cell cycle arrest in the presence of mating pheromone"]
["YDR480W","DIG2",29,4,"+",1417331,1418139,809,"ORF Verified","Regulatory protein of unknown function, pheromone-inducible, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription \n"]
["YLR326W",null,29,12,"+",782175,782935,761,"ORF Uncharacterized","Hypothetical protein"]
["YDL095W","PMT1",30,4,"+",287617,289465,1849,"ORF Verified","Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt2p, can instead interact with Pmt3p in some conditions; target for new antifungals"]
["YDR297W","SUR2",30,4,"+",1056475,1057643,1169,"ORF Verified","Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis"]
["YDR488C","PAC11",30,4,"-",1429047,1430767,1721,"ORF Verified","Dynein intermediate chain, acts in the cytoplasmic dynein pathway, forms cortical cytoplasmic microtubule capture site with Num1p; null mutant is defective in nuclear migration, essential in the absence of CIN8"]
["YER016W","BIM1",30,5,"+",188257,189073,817,"ORF Verified","Microtubule-binding protein that together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally"]
["YGR188C","BUB1",30,7,"-",872279,875151,2873,"ORF Verified","Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage, associates with centromere DNA via Skp1p"]
["YHR092C","HXT4",30,8,"-",287292,288212,921,"ORF Verified","High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose"]
["YKL008C","LAC1",30,11,"-",426816,428312,1497,"ORF Verified","Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p"]
["YMR304C-A",null,30,13,"-",879069,880381,1313,"ORF Dubious","Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SCW10"]
["YPR106W","ISR1",31,16,"+",740035,741419,1385,"ORF Verified","Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C"]
["YDR113C","PDS1",32,4,"-",680470,681702,1233,"ORF Verified","Securin that inhibits anaphase by binding separin Esp1p, also blocks cyclin destruction and mitotic exit, essential for cell cycle arrest in mitosis in the presence of DNA damage or aberrant mitotic spindles; also present in meiotic nuclei"]
["YER003C",null,32,5,"-",155693,157741,2049,"ORF Verified","PMI40Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation"]
["YMR305C","SCW10",32,{"$nulls":5},"ORF Verified","Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p"]
["YBR015C","MNN2",33,2,"-",267972,269628,1657,"ORF Verified","Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment"]
["YLR342W","FKS1",33,12,"+",809751,815607,5857,"ORF Verified","Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling"]
["YAL007C","ERP2",34,1,"-",137723,138443,721,"ORF Verified","Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles"]
["YGL093W","SPC105",34,7,"+",334851,337571,2721,"ORF Verified","Protein required for accurate chromosome segregation, localizes to the nuclear side of the spindle pole body; forms a complex with Ydr532cp"]
["YMR144W",null,34,13,"+",553249,554449,1201,"ORF Uncharacterized","uncharacterized ORF"]
["YNL088W","TOP2",34,14,"+",457657,459857,2201,"ORF Verified","Essential type II topoisomerase, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis"]
["YOR081C","STC2",34,15,"-",476885,479221,2337,"ORF Verified","Triacylglycerol lipase involved in TAG mobilization; localizes to lipid particles; potential Cdc28p substrate"]
["YOR083W","WHI5",34,15,"+",479465,481825,2361,"ORF Verified","Repressor of G1 transcription that binds to SCB binding factor (SBF) at SCB target promoters in early G1; phosphorylation of Whi5p by the CDK, Cln3p/Cdc28p relieves repression and promoter binding by Whi5; periodically expressed in G1"]
["YOR084W",null,34,{"$nulls":5},"ORF Verified","Putative lipase of the peroxisomal matrix; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance"]
["YDR356W","SPC110",35,4,"+",1186083,1188491,2409,"ORF Verified","Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nuclear microtubules to SPB; interacts with Tub4p-complex and calmodulin; phosphorylated by Mps1p in cell cycle-dependent manner"]
["YFL025C","BST1",35,6,"-",85229,87301,2073,"ORF Verified","GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents production of vesicles with defective subunits, required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules"]
["YGR014W","MSB2",35,7,"+",516683,519051,2369,"ORF Verified","Mucin family member involved in the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; also functions as an osmosensor in parallel to the Sho1p-mediated pathway; potential Cdc28p substrate"]
["YLL021W","SPA2",35,12,"+",103473,105305,1833,"ORF Verified","Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate"]
["YBL009W","ALK2",36,2,"+",207176,209048,1873,"ORF Verified","Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk1p and to mammalian haspins"]
["YGL200C","EMP24",36,7,"-",122631,123359,729,"ORF Verified","Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport"]
["YGR140W","CBF2",36,7,"+",767483,769091,1609,"ORF Verified","Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo"]
["YNL283C","WSC2",36,14,"-",105461,106725,1265,"ORF Verified","Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity and recovery from heat shock; secretory pathway Wsc2p is required for the arrest of secretion response"]
["YOR373W","NUD1",36,15,"+",1036793,1038665,1873,"ORF Verified","Component of the spindle pole body outer plaque, required for exit from mitosis"]
["YHR061C","GIC1",37,8,"-",221404,222588,1185,"ORF Verified","Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain"]
["YHR172W","SPC97",37,8,"+",448225,451241,3017,"ORF Verified","Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque"]
["YNL030W","HHF2",37,14,"+",576706,577074,369,"ORF Verified","One of two identical histone H4 proteins (see also HHF1); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity"]
["YNL166C","BNI5",37,14,"-",322557,323581,1025,"ORF Verified","Protein involved in organization of septins at the mother-bud neck, may interact directly with the Cdc11p septin, localizes to bud neck in a septin-dependent manner"]
["YPL127C","HHO1",37,16,"-",308821,309637,817,"ORF Verified","Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation"]
["YBL002W","HTB2",38,2,"+",236384,237016,633,"ORF Verified","One of two nearly identical (see HTB1) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation"]
["YDR225W","HTA1",38,4,"+",915427,916067,641,"ORF Verified","One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p"]
["YER019W","ISC1",38,5,"+",192289,192849,561,"ORF Verified","Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C, hydrolyzes complex sphingolipids to produce ceramide; activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol; mediates Na+ and Li+ halotolerance"]
["YBL031W","SHE1",39,2,"+",161695,162471,777,"ORF Verified","Cytoskeletal protein of unknown function; overexpression causes growth arrest"]
["YBR010W","HHT1",39,2,"+",256312,256824,513,"ORF Verified","One of two identical histone H3 proteins (see also HHT2); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation"]
["YDR224C","HTB1",39,4,"-",914295,914791,497,"ORF Verified","One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation"]
["YJL118W",null,39,10,"+",191601,192313,713,"ORF Verified","Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; YJL18W is a non-essential gene; deletion enhances the toxicity of heterologously expressed human alpha-synuclein"]
["YNL031C","HHT2",39,14,"-",575396,576061,666,"ORF Verified","One of two identical histone H3 proteins (see also HHT1); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation"]
["YMR117C","SPC24",40,13,"-",500709,501917,1209,"ORF Verified","Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering"]
["YPR141C","KAR3",40,16,"-",816751,818039,1289,"ORF Verified","Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate"]
["YBL003C","HTA2",41,2,"-",235276,235828,553,"ORF Verified","One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p"]
["YEL061C","CIN8",41,5,"-",36405,38157,1753,"ORF Verified","Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation"]
["YJR146W",null,41,10,"+",704065,705297,1233,"ORF Dubious","Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene HMS2"]
["YNL014W","HEF3",41,14,"+",606594,608778,2185,"ORF Verified","Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells"]
["YNL126W","SPC98",41,14,"+",387201,389809,2609,"ORF Verified","Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque"]
["YER018C","SPC25",42,5,"-",191629,192661,1033,"ORF Verified","Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering"]
["YHR086W","NAM8",42,8,"+",277944,279728,1785,"ORF Verified","RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of MER2 pre-mRNA"]
["YBR162C","TOS1",43,2,"-",562932,564780,1849,"ORF Verified","Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C"]
["YGR099W","TEL2",43,7,"+",687843,689843,2001,"ORF Verified","Essential DNA-binding protein specific to single-stranded yeast telomeric DNA repeats, required for telomere length regulation and telomere position effect"]
["YJR147W","HMS2",43,10,"+",704065,705297,1233,"ORF Verified","Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant"]
["YLR045C","STU2",43,12,"-",235021,237709,2689,"ORF Verified","Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p"]
["YNR009W","NRM1",43,14,"+",642658,643530,873,"ORF Verified","Transcriptional co-repressor of MBF (MCB binding factor)-regulated gene expression; Nrm1p associates stably with promoters via MBF to repress transcription upon exit from G1 phase"]
["YBL063W","KIP1",44,2,"+",101895,105175,1810,"ORF Verified","Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p"]
["YBR009C","HHF1",44,2,"-",255260,255716,457,"ORF Verified","One of two identical histone H4 proteins (see also HHF2); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity"]
["YIR034C","LYS1",44,9,"-",419581,420757,1177,"ORF Verified","Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway"]
["YBR184W",null,45,2,"+",598008,598920,913,"ORF Uncharacterized","Putative protein of unknown function; YBR184W is not an essential gene"]
["YMR006C","PLB2",45,13,"-",277557,279429,1873,"ORF Verified","Phospholipase B (lysophospholipase) involved in phospholipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine"]
["YOR372C","NDD1",45,15,"-",1035069,1036533,1465,"ORF Verified","Transcriptional activator essential for nuclear division; localized to the nucleus; essential component of the mechanism that activates the expression of a set of late-S-phase-specific genes"]
["YDR302W","GPI11",46,4,"+",1067675,1068219,545,"ORF Verified","ER membrane protein involved in a late step of glycosylphosphatidylinositol (GPI) anchor assembly; involved in the addition of phosphoethanolamine to the multiply mannosylated GPI intermediate; human PIG-Fp is a functional homolog"]
["YJR053W","BFA1",46,10,"+",533913,535937,2025,"ORF Verified","Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis"]
["YKL096W","CWP1",46,11,"+",260740,260860,121,"ORF Verified","Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization"]
["YPL269W","KAR9",46,16,"+",33017,34993,1977,"ORF Verified"," Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules, localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase"]
["YDR451C","YHP1",47,4,"-",1360959,1362215,1257,"ORF Verified","One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval"]
["YLR455W",null,48,12,"+",1053391,1054791,1401,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)"]
["YMR215W","GAS3",48,13,"+",696737,698337,1601,"ORF Verified","Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall"]
["YPL116W","HOS3",48,16,"+",329433,331457,2025,"ORF Verified","Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats"]
["YCR086W","CSM1",49,3,"+",263361,263929,569,"ORF Verified","Nucleolar protein that forms a complex with Lrs4p which binds Mam1p at kinetochores during meiosis I to mediate accurate chromosome segregation, may be involved in premeiotic DNA replication; possible role in telomere maintenance"]
["YGR113W","DAM1",49,7,"+",718843,720139,1297,"ORF Verified","Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; Ipl1p target for regulating kinetochore-MT attachments"]
["YOR073W","SGO1",49,15,"+",464713,466241,1529,"ORF Verified","Component of the spindle checkpoint, involved in sensing lack of tension on mitotic chromosomes; protects centromeric Rec8p at meiosis I; required for accurate chromosomal segregation at meiosis II and for mitotic chromosome stability"]
["YBR008C","FLR1",50,2,"-",253276,254884,1609,"ORF Verified","Plasma membrane multidrug transporter of the major facilitator superfamily, involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs"]
["YDR219C","MFB1",50,4,"-",905327,907015,1689,"ORF Verified","Mitochondria-associated F-box protein involved in maintenance of normal mitochondrial morphology; interacts with Skp1p through the F-box motif; preferentially localizes to the mother cell during budding"]
["YKR010C","TOF2",50,11,"-",458456,460984,2529,"ORF Verified","Nonessential mitochondrial protein of unknown function with sequence similarity to Net1p; identified as a topoisomerase I (Top1p) binding protein; displays synthetic genetic interactions with TOP1 and HPR1"]
["YLR209C","PNP1",50,12,"-",560909,561757,849,"ORF Verified","Purine nucleoside phosphorylase, specifically metabolizes inosine and guanosine nucleosides"]
["YMR163C","INP2",50,13,"-",584469,586517,2049,"ORF Verified","Peroxisome-specific receptor important for peroxisome inheritance; co-fractionates with peroxisome membranes and co-localizes with peroxisomes in vivo; physically interacts with the myosin V motor Myo2p; INP2 is not an essential gene"]
["YML085C","TUB1",50,13,"-",97941,99400,1459,"ORF Verified","Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules"]
["YEL017W","GTT3",51,5,"+",123641,124369,729,"ORF Verified","Protein of unknown function with a possible role in glutathione metabolism, as suggested by computational analysis of large-scale protein-protein interaction data; GFP-fusion protein localizes to the nuclear periphery\n"]
["YGL216W","KIP3",51,7,"+",84626,87346,2721,"ORF Verified","Kinesin-related motor protein involved in mitotic spindle positioning"]
["YLR288C","MEC3",51,12,"-",714893,717189,2297,"ORF Verified","DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric complex (Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded onto partial duplex DNA by a clamp loader complex; homolog of human and S. pombe Hus1"]
["YER011W","TIR1",52,5,"+",175209,176001,793,"ORF Verified","Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking"]
["YIR010W","DSN1",52,9,"+",375377,376657,1281,"ORF Verified","Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; important for chromosome segregation"]
["YJL105W","SET4",52,10,"+",223673,227217,3545,"ORF Verified","Protein of unknown function, contains a SET domain"]
["YKL052C","ASK1",52,11,"-",339464,340208,745,"ORF Verified","Component of the DASH complex that binds to microtubules and kinetochores and is essential for chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent ki"]
["YLR210W","CLB4",52,12,"+",562393,563501,1109,"ORF Verified","B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation"]
["YMR003W",null,52,13,"+",273081,273705,625,"ORF Uncharacterized","Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondria; YMR003W is not an essential gene"]
["YNL176C",null,52,14,"-",305869,307157,1289,"ORF Uncharacterized","hypothetical protein; has FKH1 TFBS "]
["YOL012C","HTZ1",52,15,"-",303381,304093,713,"ORF Verified","Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin"]
["YMR198W","CIK1",53,13,"+",659473,661937,2465,"ORF Verified","Kinesin-associated protein required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; has similarity to Vik1p"]
["YPL253C","VIK1",53,16,"-",70973,73045,2073,"ORF Verified","Protein that forms a complex with Kar3p at the spindle pole body, possible regulator of Kar3p function in microtubule-mediated processes; required for sister chromatid cohesion; has similarity to Cik1p"]
["YER032W","FIR1",54,5,"+",214993,217801,2809,"ORF Verified","Protein involved in 3' mRNA processing, interacts with Ref2p; potential Cdc28p substrate"]
["YIL131C","FKH1",54,9,"-",100733,102285,1553,"ORF Verified","Forkhead family transcription factor with a minor role in the expression of G2/M phase genes; negatively regulates transcriptional elongation; positive role in chromatin silencing at HML and HMR; regulates donor preference during switching"]
["YLR437C",null,54,12,"-",1011619,1012075,457,"ORF Uncharacterized","Putative protein of unknown function; epitope tagged protein localizes to the cytoplasm"]
["YBL097W","BRN1",55,2,"+",42729,43233,505,"ORF Verified","Essential protein required for chromosome condensation, likely to function as an intrinsic component of the condensation machinery, may influence multiple aspects of chromosome transmission and dynamics"]
["YDR179W-A",null,55,4,"+",819362,820635,1274,"ORF Uncharacterized","Putative protein of unknown function"]
["YGL101W",null,55,7,"+",312195,312947,753,"ORF Uncharacterized","Putative protein of unknown function; non-essential gene with similarity to YBR242W; interacts with the DNA helicase Hpr5p"]
["YJR076C","CDC11",55,10,"-",572885,575269,2385,"ORF Verified","Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM"]
["YKL048C","ELM1",55,11,"-",347000,348856,1857,"ORF Verified","Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring"]
["YKL069W",null,55,11,"+",306932,307428,497,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus"]
["YMR190C","SGS1",55,13,"-",640789,645413,4625,"ORF Verified","Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes"]
["YDL028C","MPS1",56,4,"-",400925,403405,2481,"ORF Verified","Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p"]
["YDR130C","FIN1",56,4,"-",715590,716606,1017,"ORF Verified","Spindle pole body-related intermediate filament protein, forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells, able to self-assemble, expression induced during S/G2, localization cell-cycle dependent"]
["YDR227W","SIR4",56,4,"+",917451,919779,2329,"ORF Verified","Silent information regulator that, together with SIR2 and SIR3, is involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; potentially phosphorylated by Cdc28p; some alleles of SIR4 prolong lifespan"]
["YEL016C","NPP2",56,5,"-",124773,126389,1617,"ORF Verified","Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp1p and Pho5p; activity and expression enhanced during conditions of phosphate starvation"]
["YHR031C","RRM3",56,8,"-",170837,172981,2145,"ORF Verified","DNA helicase involved in rDNA replication and Ty1 transposition; relieves replication fork pauses at telomeric regions; structurally and functionally related to Pif1p"]
["YHR146W","CRP1",56,8,"+",390297,391601,1305,"ORF Verified","Protein that binds to cruciform DNA structures"]
["YJL137C","GLG2",56,10,"-",154885,156061,1177,"ORF Verified","Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin"]
["YPR004C",null,56,16,"-",564199,565079,881,"ORF Verified","Protein with homology to mammalian electron transfer flavoprotein complex subunit ETF-alpha; has an FAD binding domain; interacts with yeast frataxin homolog Yfh1p; associates with a large complex containing several dehydrogenases"]
["YIL050W","PCL7",57,9,"+",258849,259361,513,"ORF Verified","Pho85p cyclin of the Pho80p subfamily, forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated"]
["YBL032W","HEK2",58,2,"+",160103,161359,1257,"ORF Verified","RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length"]
["YDR325W","YCG1",58,4,"+",1117115,1120227,3113,"ORF Verified","Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation and for chromatin binding of the condensin complex"]
["YBR130C","SHE3",59,2,"-",495572,496916,1345,"ORF Verified","Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance"]
["YDR326C","YSP2",59,4,"-",1121967,1125095,3129,"ORF Verified","Protein involved in programmed cell death; mutant shows resistance to cell death induced by amiodarone or intracellular acidification"]
["YKR041W",null,59,11,"+",517852,518948,1097,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus"]
["YML072C","TCB3",59,13,"-",124813,128101,3289,"ORF Verified","Contains three calcium and lipid binding domains; localized to the bud; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; mRNA is targeted to the bud via the mRNA transport system involving She2p; C-terminal portion of Tcb1p, Tcb2p and Tcb3p interact"]
["YDR089W",null,60,4,"+",622210,624410,2201,"ORF Uncharacterized","Protein of unknown function; deletion confers resistance to Nickel"]
["YBL052C","SAS3",61,2,"-",119427,121787,2361,"ORF Verified","Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality"]
["YBL068W-A",null,61,2,"+",90673,92113,1441,"ORF Dubious","dubious ORF; part of AST1 "]
["YBL069W","AST1",61,2,"+",90673,92113,1441,"ORF Verified","Peripheral membrane protein that interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane, possibly by influencing its incorporation into lipid rafts"]
["YFL017C","GNA1",61,6,"-",103997,104477,481,"ORF Verified","Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA"]
["YML065W","ORC1",61,13,"+",142129,144929,2801,"ORF Verified","Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity"]
["YML125C","PGA3",61,13,"-",20693,21725,1033,"ORF Uncharacterized","Essential protein required for maturation of Gas1p and Pho8p, protein trafficking; GFP-fusion protein localizes to the endoplasmic reticulum; null mutants have a cell separation defect"]
["YCL014W","BUD3",62,3,"+",96193,99073,2881,"ORF Verified","Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding"]
["YCL063W","VAC17",62,3,"+",17257,18393,1137,"ORF Verified","Protein involved in vacuole inheritance; acts as a vacuole-specific receptor for myosin Myo2p"]
["YER114C","BOI2",62,5,"-",390605,394005,3401,"ORF Verified","Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain\n"]
["YLL032C",null,62,12,"-",74157,76821,2665,"ORF Verified","Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL032C is not an essential gene"]
["YML052W","SUR7",62,13,"+",170377,171361,985,"ORF Verified","Putative integral membrane protein; component of eisosomes; associated with endocytosis, along with Pil1p and Lsp1p; sporulation and plasma membrane sphingolipid content are altered in mutants"]
["YNL068C","FKH2",62,14,"-",496061,497509,1449,"ORF Verified","Forkhead family transcription factor with a major role in the expression of G2/M phase genes; positively regulates transcriptional elongation; negative role in chromatin silencing at HML and HMR; substrate of the Cdc28p/Clb5p kinase"]
["YBR086C","IST2",63,2,"-",420219,423227,3009,"ORF Verified","Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process"]
["YML058W","SML1",63,13,"+",159329,159977,649,"ORF Verified","Ribonucleotide reductase inhibitor involved in regulating dNTP production; regulated by Mec1p and Rad53p during DNA damage and S phase"]
["YMR299C","DYN3",63,13,"-",864301,865341,1041,"ORF Verified","Dynein light intermediate chain (LIC); localizes with dynein, null mutant is defective in nuclear migration"]
["YDR147W","EKI1",64,4,"+",753154,755562,2409,"ORF Verified","Ethanolamine kinase, primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; also exhibits choline kinase activity"]
["YDR346C","SVF1",64,4,"-",1166943,1168799,1857,"ORF Verified","Protein with a potential role in cell survival pathways, required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis"]
["YOR129C",null,64,15,"-",566693,569613,2921,"ORF Verified","Putative component of the outer plaque of the spindle pole body; may be involved in cation homeostasis or multidrug resistance"]
["YBR123C","TFC1",65,2,"-",484868,486724,1857,"ORF Verified","One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; human homolog is TFIIIC-63"]
["YGL021W","ALK1",65,7,"+",454827,457035,2209,"ORF Verified","Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins"]
["YIL011W","TIR3",65,9,"+",333681,334273,593,"ORF Verified","Cell wall mannoprotein of the Srp1p%2FTip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth"]
["YJR092W","BUD4",65,10,"+",598649,602977,4329,"ORF Verified","Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate"]
["YKL183W","LOT5",65,11,"+",98580,99436,857,"ORF Verified","Protein of unknown function; gene expression increases in cultures shifted to a lower temperature"]
["YOL069W","NUF2",65,15,"+",198937,200393,1457,"ORF Verified","Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering"]
["YPR111W","DBF20",65,16,"+",747275,749107,1833,"ORF Verified","Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis"]
["YDR146C","SWI5",66,4,"-",748830,750342,1513,"ORF Verified","Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase"]
["YDR389W","SAC7",66,4,"+",1252003,1254467,2465,"ORF Verified","GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate"]
["YGR108W","CLB1",66,7,"+",703395,705179,1785,"ORF Verified","B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome"]
["YIL158W",null,66,9,"+",46201,46881,681,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole"]
["YLR063W",null,66,12,"+",264241,265449,1209,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR063W is not an essential gene"]
["YLR353W","BUD8",66,12,"+",833879,836151,2273,"ORF Verified","Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the proximal pole"]
["YOR315W","SFG1",66,15,"+",904761,905785,1025,"ORF Verified","Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate"]
["YPL155C","KIP2",66,16,"-",257693,259365,1673,"ORF Verified","Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle"]
["YBL029W",null,67,2,"+",166135,167327,1193,"ORF Uncharacterized","hypothetical protein"]
["YBR138C",null,67,2,"-",513636,515380,1745,"ORF Uncharacterized","Cytoplasmic protein of unknown function, potentially phosphorylated by Cdc28p; YBR138C is not an essential gene"]
["YBR242W",null,67,2,"+",704512,705240,729,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR242W is not an essential gene"]
["YFR039C",null,67,6,"-",232013,233653,1641,"ORF Uncharacterized","Putative protein of unknown function; YFR039C is not an essential gene"]
["YLR131C","ACE2",67,12,"-",405573,407021,1449,"ORF Verified","Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate"]
["YML034W","SRC1",67,13,"+",210121,211417,1297,"ORF Verified","Protein with a putative role in sister chromatid segregation, potentially phosphorylated by Cdc28p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery"]
["YMR001C","CDC5",67,13,"-",268885,271325,2441,"ORF Verified","Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and SPBs; has multiple functions in mitosis and cytokinesis through phosphorylation of substrates; may be a Cdc28p substrate"]
["YMR001C-A",null,67,13,"-",271357,271517,161,"ORF Uncharacterized","Putative protein of unknown function"]
["YPR119W","CLB2",67,16,"+",771259,773443,2185,"ORF Verified","B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome"]
["YDL074C","BRE1",68,4,"-",324005,326221,2217,"ORF Verified","E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on K4 and K79), contains RING finger domain"]
["YMR132C","JLP2",68,13,"-",534741,535605,865,"ORF Uncharacterized","Protein of unknown function, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)"]
["YMR183C","SSO2",68,13,"-",626701,627869,1169,"ORF Verified","Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p"]
["YOR025W","HST3",68,15,"+",378201,379561,1361,"ORF Verified","Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism"]
["YPL141C",null,68,16,"-",283517,285357,1841,"ORF Uncharacterized","Putative protein kinase; similar to Kin4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL141C is not an essential gene"]
["YHR023W","MYO1",69,8,"+",151641,155521,3881,"ORF Verified","Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively"]
["YJL051W",null,69,10,"+",340113,342169,2057,"ORF Uncharacterized","Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent transport system; mRNA is cell cycle regulated via Fkh2p, peaking in G2/M phase; null mutant displays increased levels of spontaneous Rad52 foci"]
["YOR058C","ASE1",69,15,"-",434573,436437,1865,"ORF Verified","Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for spindle elongation and stabilization; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate"]
["YOR104W","PIN2",69,15,"+",517625,518857,1233,"ORF Verified","Protein that induces appearance of %5BPIN+%5D prion when overproduced"]
["YOR105W",null,69,15,"+",517625,518857,1233,"ORF Dubious","hypothetical protein (adjacent to YOR104W)"]
["YOR346W","REV1",69,15,"+",981665,984889,3225,"ORF Verified","Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA"]
["YBL005W","PDR3",70,2,"+",217512,220608,3097,"ORF Verified","Transcriptional activator of the pleiotropic drug resistance network, regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting sites known as PDREs (PDR responsive elements)"]
["YIL106W","MOB1",70,9,"+",166521,167497,977,"ORF Verified","Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex"]
["YKL130C","SHE2",70,11,"-",195464,196056,593,"ORF Verified","RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud"]
["YLR190W","MMR1",70,12,"+",534961,536953,1993,"ORF Verified","Phosphorylated protein of the mitochondrial outer membrane, localizes only to mitochondria of the bud; interacts with Myo2p to mediate mitochondrial distribution to buds; mRNA is targeted to the bud via the transport system involving She2p"]
["YMR102C",null,70,13,"-",469741,472605,2865,"ORF Uncharacterized","Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene"]
["YOR056C","NOB1",70,15,"-",430285,431701,1417,"ORF Verified","Essential nuclear protein involved in proteasome maturation and synthesis of 40S ribosomal subunits; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA"]
["YOR064C","YNG1",70,15,"-",446005,446757,753,"ORF Verified","Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3, has similarity to the human tumor suppressor ING1"]
["YDR514C",null,71,4,"-",1471511,1473023,1513,"ORF Uncharacterized","hypothetical protein"]
["YHL028W","WSC4",71,8,"+",48729,50273,1545,"ORF Verified","ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; exhibits functional overlap with WSC family members involved in the stress response"]
["YNL172W","APC1",71,14,"+",311241,316081,4841,"ORF Verified","Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition"]
["YOL124C","TRM11",71,15,"-",85477,86781,1305,"ORF Verified","Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain \n"]
["YBR267W","REI1",72,2,"+",739832,741120,1289,"ORF Verified"," Protein of unknown function involved in bud growth in the mitotic signaling network; proposed negative regulator of Swe1p and Gin4p; contains dispersed C2H2 zinc finger domains"]
["YGR145W","ENP2",72,7,"+",781731,783723,1993,"ORF Verified","Essential nucleolar protein of unknown function; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p"]
["YKL078W","DHR2",72,11,"+",288468,290668,2201,"ORF Verified","Predominantly nucleolar DEAH-box RNA helicase, required for 18S rRNA synthesis"]
["YLL028W","TPO1",72,12,"+",84681,86913,2233,"ORF Verified","Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane"]
["YML064C","TEM1",72,13,"-",145181,145957,777,"ORF Verified","GTP-binding protein of the ras superfamily involved in termination of M-phase; controls actomyosin and septin dynamics during cytokinesis"]
["YMR032W","HOF1",72,13,"+",335209,337177,1969,"ORF Verified","Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p"]
["YNL024C",null,72,14,"-",587246,587854,609,"ORF Uncharacterized","Putative protein of unknown function with seven beta-strand methyltransferase motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL024C is not an essential gene"]
["YNL151C","RPC31",72,14,"-",347669,348581,913,"ORF Verified","RNA polymerase III subunit C31; contains HMG-like C-terminal domain"]
["YOR313C","SPS4",72,15,"-",901741,903397,1657,"ORF Verified","Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage"]
["YPR156C","TPO3",72,16,"-",839447,840071,625,"ORF Verified","Polyamine transport protein specific for spermine; localizes to the plasma membrane; member of the major facilitator superfamily"]
["YCR024C-A","PMP1",73,3,"-",162653,163261,609,"ORF Verified","May regulate plasma membrane H(+)-ATPase; Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p)"]
["YCR024C-B",null,73,3,"-",162653,163261,609,"ORF Uncharacterized","Putative protein of unknown function; identified by expression profiling and mass spectrometry"]
["YDL063C",null,73,4,"-",338469,340221,1753,"ORF Uncharacterized","hypothetical protein"]
["YIL122W","POG1",73,9,"+",130489,131737,1249,"ORF Verified","Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated"]
["YJR003C",null,73,10,"-",440869,442461,1593,"ORF Uncharacterized","Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies"]
["YKR021W","ALY1",73,11,"+",478820,481748,2929,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm"]
["YKR081C","RPF2",73,11,"-",591136,592200,1065,"ORF Verified","Essential protein involved in the processing of pre-rRNA and the assembly of the 60S ribosomal subunit; interacts with ribosomal protein L11; localizes predominantly to the nucleolus; constituent of 66S pre-ribosomal particles"]
["YLR003C",null,73,12,"-",156765,157757,993,"ORF Uncharacterized","Putative protein of unknown function that may participate in DNA replication; green fluorescent protein (GFP)-fusion protein is localized to the nucleus; YLR003C is not an essential gene"]
["YNR004W",null,73,14,"+",635930,636746,817,"ORF Uncharacterized","Putative protein of unknown function; haploid disruptant exhibits slow growth rate on glucose-minimal medium at 15 C"]
["YPR157W",null,73,16,"+",841211,842491,1281,"ORF Uncharacterized","Putative protein of unknown function"]
["YDR020C",null,74,4,"-",485405,486557,1153,"ORF Uncharacterized","Predicted protein shares weak similarity with uridine kinases and with phosphoribokinases; null mutant suppresses dst1delta sensitivity for 6-azauracil"]
["YHR148W","IMP3",74,8,"+",393521,394321,801,"ORF Verified","Component of the SSU processome, which is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA"]
["YLR057W",null,74,12,"+",255265,257889,2625,"ORF Uncharacterized","Putative protein of unknown function; YLR050C is not an essential gene"]
["YNL056W","OCA2",74,14,"+",517234,517866,633,"ORF Verified","Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene"]
["YNL058C",null,74,14,"-",516070,516766,697,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene"]
["YNL141W","AAH1",74,14,"+",359601,360361,761,"ORF Verified","Adenine deaminase (adenine aminohydrolase), involved in purine salvage and nitrogen catabolism"]
["YNL308C","KRI1",74,14,"-",54141,55925,1785,"ORF Verified","Essential nucleolar protein required for 40S ribosome biogenesis; physically and functionally interacts with Krr1p"]
["YOR101W","RAS1",74,15,"+",515145,516345,1201,"ORF Verified","GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes"]
["YPL058C","PDR12",74,16,"-",445695,450455,4761,"ORF Verified","Plasma membrane ATP-binding cassette (ABC) transporter, weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity"]
["YBR255W",null,75,2,"+",724472,726576,2105,"ORF Uncharacterized","Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern"]
["YER031C","YPT31",75,5,"-",213917,214773,857,"ORF Verified","GTPase of the Ypt/Rab family, very similar to Ypt32p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi"]
["YER140W",null,75,5,"+",451529,453137,1609,"ORF Uncharacterized","Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies"]
["YGL116W","CDC20",75,7,"+",289675,291707,2033,"ORF Verified","Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate"]
["YIL092W",null,75,9,"+",190881,193425,2545,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus"]
["YLR363W-A",null,75,12,"+",853447,854015,569,"ORF Uncharacterized","hypothetical protein"]
["YML119W",null,75,13,"+",30561,31393,833,"ORF Uncharacterized","Putative protein of unknown funtion; YML119W is not an essential gene; potential Cdc28p substrate"]
["YOL014W",null,75,15,"+",299497,300217,721,"ORF Uncharacterized","Putative protein of unknown function"]
["YOL158C","ENB1",75,15,"-",19853,21109,1257,"ORF Verified","Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment"]
["YBL004W","UTP20",76,2,"+",233672,234768,1097,"ORF Verified","Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA"]
["YDR324C","UTP4",76,4,"-",1114655,1116711,2057,"ORF Verified","Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA"]
["YGR177C","ATF2",76,7,"-",848815,850495,1681,"ORF Verified","Alcohol acetyltransferase, may play a role in steroid detoxification; forms volatile esters during fermentation, which is important in brewing"]
["YLR276C","DBP9",76,12,"-",695221,696917,1697,"ORF Verified","ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit"]
["YMR009W","ADI1",76,13,"+",284057,284585,529,"ORF Verified","Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions"]
["YMR294W","JNM1",76,13,"+",856961,858081,1121,"ORF Verified","Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B"]
["YOL144W","NOP8 ",76,15,"+",53057,54481,1425,"ORF Verified","Nucleolar protein required for 60S ribosomal subunit biogenesis"]
["YOR023C","AHC1",76,15,"-",376013,376229,217,"ORF Verified","Subunit of the Ada histone acetyltransferase complex, required for structural integrity of the complex"]
["YOR319W","HSH49",76,15,"+",912793,913569,777,"ORF Verified","U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM)"]
["YPR149W","NCE102",76,16,"+",829731,830507,777,"ORF Verified","Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs)"]
["YAL025C","MAK16",77,1,"-",100059,101171,1113,"ORF  Verified","Essential nuclear protein, constituent of 66S pre-ribosomal particles; required for normal concentration of free 60S ribosomal subunits; required for maintenance of M1 satellite double-stranded RNA of the L-A virus \n"]
["YAL059W","ECM1",77,1,"+",36545,37097,553,"ORF Verified","Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export"]
["YFR001W","LOC1",77,6,"+",149097,149561,465,"ORF Verified","Nuclear protein involved in asymmetric localization of ASH1 mRNA; binds double-stranded RNA in vitro; constituent of 66S pre-ribosomal particles"]
["YGR068C",null,77,7,"-",624983,627119,2137,"ORF Uncharacterized","Putative protein of unknown function; YGR068C is not an essential gene."]
["YLR297W",null,77,12,"+",723921,724545,625,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YLR297W is not an essential gene"]
["YOL070C",null,77,15,"-",197509,198477,969,"ORF Verified","Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, and bud neck; potential Cdc28p substrate"]
["YPL183C",null,77,16,"-",199773,201357,1585,"ORF Uncharacterized","Cytoplasmic protein of unknown function"]
["YPR112C","MRD1",77,16,"-",749359,751951,2593,"ORF Verified","Essential conserved protein that associates with 35S precursor rRNA and is required for its initial processing at the A(0)-A(2) cleavage sites, shows partial nucleolar localization, contains five consensus RNA-binding domains"]
["YDL153C","SAS10",78,4,"-",181405,183037,1633,"ORF Verified","Component of the small (ribosomal) subunit (SSU) processosome required for pre-18S rRNa processing; essential nucleolar protein that, when overproduced, disrupts silencing"]
["YDR083W","RRP8",78,4,"+",613178,617482,4305,"ORF Verified","Protein involved in rRNA processing; involved in pre-rRNA cleavage at site A2; mutation is synthetically lethal with a gar1 mutation \n"]
["YDR183C-A",null,78,4,"-",827367,830407,3041,"ORF Dubious","hypothetical protein overlapping with ATC1 "]
["YER139C",null,78,5,"-",450005,451333,1329,"ORF Uncharacterized","Putative protein of unknown function; YER139C has been shown to be required for growth at high temperatures; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm"]
["YHR046C","INM1",78,8,"-",197477,198333,857,"ORF Verified","Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messenger signaling; INM1 expression increases in the presence of inositol and decreases upon exposure to antibipolar drugs lithium and valproate"]
["YNL110C","NOP15",78,14,"-",417877,418525,649,"ORF Verified","Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm"]
["YOR262W",null,78,15,"+",817241,818361,1121,"ORF Uncharacterized","Cytoplasmic protein of unknown function; essential gene with similarity to YLR243W; contains an ATP/GTP binding site motif"]
["YOR274W","MOD5",78,15,"+",837665,838881,1217,"ORF Verified","Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms"]
["YAR018C","KIN3",79,1,"-",170403,171707,1305,"ORF Verified","Nonessential protein kinase with unknown cellular role"]
["YDR033W","MRH1",79,4,"+",507810,509578,1769,"ORF Verified","Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p"]
["YGR143W","SKN1",79,7,"+",774947,777627,2681,"ORF Verified","Protein involved in sphingolipid biosynthesis; type II membrane protein with similarity to Kre6p"]
["YHR151C",null,79,8,"-",399349,401005,1657,"ORF Uncharacterized","Putative protein of unknown function"]
["YHR152W","SPO12",79,8,"+",401337,402049,713,"ORF Verified","Nucleolar protein of unknown function, positive regulator of exit from mitosis; involved in regulating the release of Cdc14p from the nucleolus in early anaphase; proposed to play similar role in meiosis"]
["YKL129C","MYO3",79,11,"-",196360,199960,3601,"ORF Verified","One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization"]
["YOR001W","RRP6",79,15,"+",326809,328985,2177,"ORF Verified","Exonuclease component of the nuclear exosome; contributes to the quality-control system that retains and degrades aberrant mRNAs in the nucleus"]
["YBL067C","UBP13",80,2,"-",89493,93645,4153,"ORF Verified","Putative ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions"]
["YBR092C","PHO3",80,2,"-",427659,429115,1457,"ORF Verified","Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin"]
["YBR139W",null,80,2,"+",515656,516992,1337,"ORF Verified","hypothetical protein"]
["YCR090C",null,80,3,"-",272293,272877,585,"ORF Uncharacterized","hypothetical protein"]
["YDR308C","SRB7",80,4,"-",1077911,1078463,553,"ORF Verified","RNA polymerase II holoenzyme component \n\n"]
["YGL162W","SUT1",80,7,"+",198019,199059,1041,"ORF Verified","Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression"]
["YGR092W","DBF2",80,7,"+",668147,670051,1905,"ORF Verified","Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis"]
["YMR031C",null,80,13,"-",332381,334805,2425,"ORF Uncharacterized","Protein of unknown function with similarity to Ykl050cp and Uso1p; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; YMR031C is not an essential gene"]
["YDR465C","RMT2",81,4,"-",1393303,1394615,1313,"ORF Verified","Arginine methyltransferase; ribosomal protein L12 is a substrate \n\n"]
["YGR070W","ROM1",81,7,"+",627795,630891,3097,"ORF Verified","GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP"]
["YOR229W","WTM2",81,15,"+",768337,769985,1649,"ORF Verified","Transcriptional repressor involved in regulation of meiosis and silencing; contains WD repeats"]
["YOR273C","TPO4",81,15,"-",834349,836493,2145,"ORF Verified","Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily"]
["YPL148C","PPT2",81,16,"-",272157,272909,753,"ORF Verified","Phosphopantetheine:protein transferase (PPTase), activates mitochondrial acyl carrier protein (Acp1p) by phosphopantetheinylation"]
["YDR198C","RKM2",82,4,"-",852671,853975,1305,"ORF Verified","Ribosomal protein lysine methyltransferase, responsible for epsilon-trimethylation of the lysine residue at position 10 of Rpl12Ap and Rpl12Bp"]
["YGR230W","BNS1",82,7,"+",951771,952395,625,"ORF Verified","Protein with some similarity to Spo12p; overexpression bypasses need for Spo12p, but not required for meiosis"]
["YJL077W-B",null,82,10,"+",293545,294729,1185,"ORF Uncharacterized","Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching"]
["YNL032W","SIW14",82,14,"+",574377,575297,921,"ORF Verified","Tyrosine phosphatase that plays a role in actin filament organization and endocytosis; localized to the cytoplasm"]
["YOR049C","RCB1",82,15,"-",422557,423933,1377,"ORF Verified","Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation; putative integral membrane transporter or flippase that may transport LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane"]
["YAL022C","FUN26",83,1,"-",108859,110451,1593,"ORF Verified","Nucleoside transporter with broad nucleoside selectivity; localized to intracellular membranes"]
["YCR095W-A",null,83,3,"+",289545,291057,1513,"ORF Uncharacterized","Putative protein of unknown function"]
["YER053C-A",null,83,5,"-",260733,261077,345,"ORF Uncharacterized","hypothetical protein"]
["YHL026C",null,83,8,"-",53133,54237,1105,"ORF Uncharacterized","Putative protein of unknown function; YHL026C is not an essential gene; in 2005 the start site was moved 141 nt upstream (see Locus History)"]
["YCR042C","TAF2",84,3,"-",201101,205405,4305,"ORF Verified","TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation"]
["YLR254C","NDL1",84,12,"-",644357,645061,705,"ORF Verified","Homolog of nuclear distribution factor NudE, NUDEL; interacts with Pac1p and regulates dynein targeting to microtubule plus ends"]
["YDL039C","PRM1",85,4,"-",381981,384845,2865,"ORF Verified"," Pheromone-regulated protein, predicted to have one transmembrane segment; promoter contains Gcn4p binding elements"]
["YER037W","PHM8",85,5,"+",225825,227001,1177,"ORF Verified","Protein of unknown function, expression is induced by low phosphate levels and by inactivation of Pho85p"]
["YFL050C","ALR2",85,6,"-",33149,35845,2697,"ORF Verified","Probable Mg(2+) transporter; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions"]
["YJL079C","PRY1",85,10,"-",289645,290845,1201,"ORF Verified","Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins"]
["YMR253C",null,85,13,"-",775789,777229,1441,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YMR253C is not an essential gene"]
["YNL298W","CLA4",85,14,"+",69225,71065,1841,"ORF Verified","Cdc42p activated signal transducing kinase of the PAK (p21-activated kinase) family, involved in septin ring assembly and cytokinesis; directly phosphorylates septins Cdc3p and Cdc10p; other yeast PAK family members are Ste20p and Skm1p"]
["YAL040C","CLN3",86,1,"-",65611,67843,2233,"ORF Verified","G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis"]
["YBR200W","BEM1",86,2,"+",620816,622680,1865,"ORF Verified","Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p"]
["YDL138W","RGT2",86,4,"+",213185,215129,1945,"ORF Verified","Plasma membrane glucose receptor, highly similar to Snf3p; both Rgt2p and Snf3p serve as transmembrane glucose sensors generating an intracellular signal that induces expression of glucose transporter (HXT) genes"]
["YIL167W","SDL1",86,9,"+",28961,30177,1217,"pseudogene","hypothetical protein; constitutes an ORF with YIL168W"]
["YBR202W","MCM7",87,2,"+",625704,627288,1585,"ORF Verified","Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase"]
["YIL168W",null,87,9,"+",28961,30177,1217,"pseudogene","L-serine dehydratase goes together with SDL1"]
["YMR233W",null,87,13,"+",739169,740009,841,"ORF Verified","uncharacterized ORF"]
["YNL160W","YGP1",87,14,"+",336497,337825,1329,"ORF Verified","Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p"]
["YBR085C-A",null,88,2,"-",418715,419251,537,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus"]
["YGL201C","MCM6",88,7,"-",118031,120967,2937,"ORF Verified","Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex"]
["YJL084C","ALY2",88,10,"-",275237,278029,2793,"ORF Verified","Cytoplasmic protein of unknown function that interacts with the cyclin Pcl7p; phosphorylated in vitro by the cyclin-CDK complex, Pcl7p-Pho85p; identified as a potential Cdc28p substrate; mRNA is cell cycle regulated, peaking in M phase"]
["YLR237W","THI7",88,12,"+",612305,614145,1841,"ORF Verified","Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia"]
["YOR127W","RGA1",88,15,"+",561529,563905,2377,"ORF Verified","GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth"]
["YOR228C",null,88,15,"-",766741,767997,1257,"ORF Verified","Protein of unknown function, localized to the mitochondrial outer membrane"]
["YDR493W","FMP36",89,4,"+",1436139,1436523,385,"ORF Uncharacterized","The authentic, non-tagged protein was localized to the mitochondria"]
["YJL044C","GYP6",89,10,"-",358093,359141,1049,"ORF Verified","GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport"]
["YDL044C","MTF2",90,4,"-",374077,375629,1553,"ORF Verified","Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription"]
["YJL157C","FAR1",90,10,"-",123773,126277,2505,"ORF Verified","Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate"]
["YKL209C","STE6",90,11,"-",42421,45261,2841,"ORF Verified","ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport, contains 12 transmembrane domains and two ATP binding domains, expressed only in MATa cells"]
["YNL329C","PEX6",90,14,"-",19525,22621,3097,"ORF Verified","AAA-peroxin that heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol"]
["YBL023C","MCM2",91,2,"-",174939,177579,2641,"ORF Verified","Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex"]
["YDR191W","HST4",92,4,"+",842315,843219,905,"ORF Verified","Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism"]
["YHR005C","GPA1",92,8,"-",113421,114997,1577,"ORF Verified","GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors; negatively regulates the mating pathway by sequestering G(beta)gamma and by triggering an adaptive response; activates Vps34p at the endosome"]
["YOL154W","ZPS1",92,15,"+",34449,35417,969,"ORF Verified","Putative GPI-anchored protein; transcription is induced under low-zinc conditions, as mediated by the Zap1p transcription factor, and at alkaline pH"]
["YEL032W","MCM3",93,5,"+",86889,89393,2505,"ORF Verified","Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex"]
["YLR274W","MCM5",93,12,"+",691529,693857,2329,"ORF Verified","Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase"]
["YNL146C-A",null,93,14,"-",351157,351757,601,"ORF Uncharacterized","Putative protein of unknown function"]
["YOR066W",null,93,15,"+",450097,451145,1049,"ORF Uncharacterized","Protein of unknown function; potential Cdc28p substrate; YOR066W is not an essential gene"]
["YHR075C","PPE1",94,8,"-",248460,249684,1225,"ORF Verified","Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein"]
["YOR126C","IAH1",94,15,"-",559917,560709,793,"ORF Verified","Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing"]
["YDL117W","CYK3",95,4,"+",248305,251137,2833,"ORF Verified","SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring; mutant phenotype and genetic interactions suggest a role in cytokinesis"]
["YKL185W","ASH1",95,11,"+",94324,95940,1617,"ORF Verified","Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate"]
["YNL188W","KAR1",95,14,"+",286297,287497,1201,"ORF Verified","Essential protein involved in karyogamy during mating and in spindle pole body duplication during mitosis, localizes to the half-bridge of the spindle pole body, interacts with Spc72p during karyogamy, also interacts with Cdc31p"]
["YPL061W","ALD6",95,16,"+",432547,434147,1601,"ORF Verified","Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress"]
["YPL158C",null,95,16,"-",252853,254365,1513,"ORF Uncharacterized","Hypothetical protein"]
["YBR054W","YRO2",96,2,"+",342768,344312,1545,"ORF Verified","Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; transcriptionally regulated by Haa1p"]
["YJL159W","HSP150",96,10,"+",120409,121833,1425,"ORF Verified","O-mannosylated heat shock protein that is secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation"]
["YOR018W","ROD1",96,15,"+",366817,366993,177,"ORF Verified","Membrane protein; overexpression confers resistance to the GST substrate o-dinitrobenzene as well as to zinc and calcium; contains 2 PY motifs, which are required for Rod1p interaction with Rsp5p, a hect-type ubiquitin ligase"]
["YDL179W","PCL9",97,4,"+",138217,139225,1009,"ORF Verified","Cyclin, forms a functional kinase complex with Pho85p cyclin-dependent kinase (Cdk), expressed in late M/early G1 phase, activated by Swi5p"]
["YGR042W",null,98,{"$nulls":5},"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus"]
["YJL194W","CDC6",98,10,"+",69313,70289,977,"ORF Verified","Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p"]
["YLR273C","PIG1",98,12,"-",689085,691253,2169,"ORF Verified","Putative targeting subunit for the type-1 protein phosphatase Glc7p that tethers it to the Gsy2p glycogen synthase"]
["YBR083W","TEC1",99,2,"+",409127,410679,1553,"ORF Verified","Transcription factor required for full Ty1 epxression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA%2FATTS DNA-binding domain family member"]
["YBR157C","ICS2",99,2,"-",553644,554428,785,"ORF Verified","Protein of unknown function; null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization"]
["YDR180W","SCC2",99,4,"+",825243,825747,505,"ORF Verified","Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX"]
["YER150W","SPI1",99,5,"+",468345,468841,497,"ORF Verified","GPI-anchored, serine/threonine rich cell wall protein of unknown function; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; similar to Sed1p"]
["YGR222W","PET54",99,7,"+",939675,939955,281,"ORF Verified","Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet122p and Pet494p; also required for splicing of the COX1 intron AI5 beta; located in the mitochondrial inner membrane"]
["YKL062W","MSN4",99,11,"+",322876,324572,1697,"ORF Verified","Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression\n"]
["YNL046W",null,99,14,"+",542594,542954,361,"ORF Uncharacterized","uncharacterized ORF"]
["YNL328C","MDJ2",99,{"$nulls":5},"ORF Verified","Constituent of the mitochondrial import motor associated with the presequence translocase; function overlaps with that of Pam18p; stimulates the ATPase activity of Ssc1p to drive mitochondrial import; contains a J domain"]
["YOL101C","IZH4",99,15,"-",126949,127965,1017,"ORF Verified","Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism\n"]
["YBR038W","CHS2","NA",2,"+",311856,313120,1265,"ORF Verified","Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis"]
["YDR150W","NUM1","NA",4,"+",759786,761458,1673,"ORF Verified","Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex"]
["YGR098C","ESP1","NA",7,"-",683655,685991,2337,"ORF Verified","Separase with cysteine protease activity (related to caspases) that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibited by Pds1p"]
["YIR019C","MUC1","NA",9,"-",393157,393669,513,"ORF Verified","GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)"]
["YJL092W","HPR5","NA",10,"+",257145,259097,1953,"ORF Verified","DNA helicase and DNA-dependent ATPase involved in DNA repair, needed for proper timing of commitment to meiotic recombination and transition from Meiosis I to II; affects genome stability by suppressing unscheduled homologous recombination"]
["YKR054C","DYN1","NA",11,"-",542336,547616,5281,"ORF Verified","Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p"]
["YPL032C","SVL3","NA",16,"-",488885,491362,2478,"ORF Verified","Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck"]
["YPL162C",null,"NA",16,"-",242741,243613,873,"ORF Uncharacterized","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of vacuole with cell cycle-correlated morphology"]
["YPL230W",null,"NA",16,"+",115313,115865,553,"ORF Verified","Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis"]
["YPL242C","IQG1","NA",16,"-",93517,95149,1633,"ORF Verified","Essential protein required for determination of budding pattern, promotes localization of axial markers Bud4p and Cdc12p and functionally interacts with Sec3p, localizes to the contractile ring during anaphase, member of the IQGAP family"]
["YPR019W","cdc54","NA",16,"+",598083,599323,1241,"ORF Verified","Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p"]

{"sheet":" 37 antisense cycling","index":1,"n_rows":40,"n_cols":9,"rows_kept":40,"flags":["formulas_cached_only"]}
["overlapping sense feature","gene name","peak","chr","strand","start","end","length","function of the sense counterpart"]
["YJR146W, YJR147W","HMS2",0,10,"-",703349,705149,1801,"Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant"]
["YEL041W","YEF1",8,5,"-",76101,77413,1313,"ATP-NADH kinase; phosophorylates both NAD and NADH; homooctameric structure consisting of 60-kDa subunits; sequence similarity to Utr1p and Pos5p; overexpression complements certain pos5 phenotypes"]
["YIL166C",null,8,9,"+",31185,32561,1377,"Putative protein with similarity to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; YIL166C is a non-essential gene"]
["YDL128W","VCX1",11,4,"-",232869,233909,1041,"Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter"]
["YOR026W","BUB3",14,15,"-",380333,380469,null,"Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p"]
["YLR030W, YLR031W",null,15,12,"-",203261,204717,1457,"Putative protein of unknown function"]
["YLR050C",null,15,12,"+",245577,246177,601,"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR050C is not an essential gene"]
["YHR177W",null,16,8,"-",456343,458487,2145,"Putative protein of unknown function"]
["YKL221W","MCH2",16,11,"-",6205,7749,1545,"Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport"]
["YPR134W","MSS18",17,16,"-",798015,799023,1009,"Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions"]
["YLR341W","SPO77",18,12,"-",807211,808699,1489,"Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis"]
["YMR178W",null,21,13,"-",618389,619429,1041,"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS; YMR178W is not an essential gene"]
["YPL162C",null,21,16,"+",243193,244217,1025,"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of vacuole with cell cycle-correlated morphology"]
["YDR135C","YCF1",23,4,"+",722298,723026,729,"Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR"]
["YKL101W","HSL1",23,11,"-",251040,251384,345,"Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p"]
["YMR253C",null,23,13,"+",775985,776769,null,"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YMR253C is not an essential gene"]
["YDR221W","GTB1",25,4,"-",908055,909407,1353,"Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p, involved in removal of two glucose residues from N-linked glycans during glycoprotein biogenesis in the ER"]
["YHR142W","CHS7",29,8,"-",383677,384573,897,"Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER"]
["YPL230W","USV1",31,16,"-",114485,116357,null,"Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis"]
["YIL063C","YRB2",34,9,"+",243633,243929,null,"Protein of unknown function involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; is not essential"]
["YPL249C","GYP5",38,16,"+",76705,78609,null,"GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p"]
["YCR042C","TAF2",43,3,"+",202729,204209,1481,"TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation"]
["YJL157C","FAR1",43,10,"+",123737,125449,1713,"Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate"]
["YML087C",null,49,13,"+",94457,95585,null,"Putative protein of unknown function"]
["YNL134C",null,51,14,"+",372473,374273,1801,"Putative protein of unknown function with similarity to dehydrogenases from other model organisms; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced by the DNA-damaging agent MMS"]
["YHR139C","SPS100",53,8,"+",378137,380073,1937,"Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall"]
["YOR097C",null,57,15,"+",506945,507817,873,"Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen; YOR097C is not an essential gene"]
["YBR067C","TIP1",58,2,"+",372119,372543,425,"Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins"]
["YKL127W","PGM1",66,11,"-",203832,204600,769,"Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism"]
["YGL021W","ALK1",68,7,"-",454935,455087,null,"Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins"]
["YPR135W","CTF4",74,16,"-",799783,800391,609,"Chromatin-associated protein, required for sister chromatid cohesion; interacts with DNA polymerase alpha (Pol1p) and may link DNA synthesis to sister chromatid cohesion"]
["YBR180W","DTR1",75,2,"-",590100,591348,1249,"Multidrug resistance dityrosine transporter of the major facilitator superfamily, essential for spore wall synthesis, facilitates the translocation of bisformyl dityrosine through the prospore membrane"]
["YPR194C, YPR195C","OPT2 excluded",78,16,"+",924291,928339,4049,"Oligopeptide transporter; member of the OPT family, with potential orthologs in S. pombe and C. albicans"]
["YJL078C","PRY3",80,10,"+",291913,293537,1625,"Protein of unknown function, has similarity to Pry1p and Pry2p and to the plant PR-1 class of pathogen related proteins"]
["YMR181C",null,82,13,"+",623585,625281,null,"Protein of unknown function; mRNA transcribed as part of a bicistronic transcript with a predicted transcriptional repressor RGM1/YMR182C; mRNA is destroyed by nonsense-mediated decay (NMD); YMR181C is not an essential gene"]
["YNL300W",null,82,14,"-",65757,66037,281,"Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid"]
["YAR035W","YAT1",null,1,"-",189427,191819,2393,"Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated"]
[]
["for which opposite ORF cycles"]

{"sheet":"11 novel cycling","index":2,"n_rows":12,"n_cols":6,"rows_kept":12,"flags":["formulas_cached_only"]}
["chr","strand","start","end","length","peak"]
[4,"-",1340831,1342151,1321,11]
[4,"-",1018103,1019103,1001,13]
[5,"-",187029,188061,1033,16]
[4,"+",80713,82633,1921,19]
[4,"-",443805,444173,369,20]
[7,"+",166923,167347,425,21]
[2,"+",254640,254864,225,34]
[16,"+",286673,286993,321,69]
[4,"-",506510,507078,569,76]
[2,"+",430975,431591,617,83]
[4,"+",49921,50857,937,98]