{"text_format":"3","workbook":"xls","n_sheets":3,"sheets":["37 periodic antisense","43 non-periodic antisense","Sheet3"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"37 periodic antisense","index":0,"n_rows":38,"n_cols":10,"rows_kept":38,"flags":["formulas_cached_only"]}
["overlapping sense transcript","gene name","peak","chr","strand","start","end","length","function of the sense counterpart (SGD description)","sense cycling"]
["YJR146W, YJR147W","HMS2",0,10,"-",703349,705149,1801,"Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant","yes"]
["YEL041W","YEF1",8,5,"-",76101,77413,1313,"ATP-NADH kinase; phosophorylates both NAD and NADH; homooctameric structure consisting of 60-kDa subunits; sequence similarity to Utr1p and Pos5p; overexpression complements certain pos5 phenotypes","no"]
["YIL166C",null,8,9,"+",31185,32561,1377,"Putative protein with similarity to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; YIL166C is a non-essential gene","no"]
["YDL128W","VCX1",11,4,"-",232869,233909,1041,"Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter","no"]
["YOR026W","BUB3",14,15,"-",380333,380469,"NA","Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p","no"]
["YLR030W, YLR031W",null,15,12,"-",203261,204717,1457,"Putative protein of unknown function","no"]
["YLR050C",null,15,12,"+",245577,246177,601,"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR050C is not an essential gene","yes"]
["YHR177W",null,16,8,"-",456343,458487,2145,"Putative protein of unknown function","no"]
["YKL221W","MCH2",16,11,"-",6205,7749,1545,"Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport","no"]
["YPR134W","MSS18",17,16,"-",798015,799023,1009,"Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions","no"]
["YLR341W","SPO77",18,12,"-",807211,808699,1489,"Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis","no"]
["YMR178W",null,21,13,"-",618389,619429,1041,"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS; YMR178W is not an essential gene","no"]
["YPL162C",null,21,16,"+",243193,244217,1025,"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of vacuole with cell cycle-correlated morphology","yes"]
["YKL101W","HSL1",23,11,"-",251040,251384,345,"Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p","yes"]
["YDR135C","YCF1",23,4,"+",722298,723026,729,"Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR","no"]
["YMR253C",null,23,13,"+",775985,776769,"NA","Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YMR253C is not an essential gene","yes"]
["YDR221W","GTB1",25,4,"-",908055,909407,1353,"Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p, involved in removal of two glucose residues from N-linked glycans during glycoprotein biogenesis in the ER","no"]
["YHR142W","CHS7",29,8,"-",383677,384573,897,"Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER","no"]
["YAR035W","YAT1",29,1,"-",189427,191819,2393,"Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated","no"]
["YPL230W","USV1",31,16,"-",114485,116357,"NA","Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis","yes"]
["YIL063C","YRB2",34,9,"+",243633,243929,"NA","Protein of unknown function involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; is not essential","no"]
["YPL249C","GYP5",38,16,"+",76705,78609,"NA","GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p","no"]
["YCR042C","TAF2",43,3,"+",202729,204209,1481,"TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation","yes"]
["YJL157C","FAR1",43,10,"+",123737,125449,1713,"Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate","yes"]
["YML087C",null,49,13,"+",94457,95585,"NA","Putative protein of unknown function","no"]
["YNL134C",null,51,14,"+",372473,374273,1801,"Putative protein of unknown function with similarity to dehydrogenases from other model organisms; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced by the DNA-damaging agent MMS","no"]
["YHR139C","SPS100",53,8,"+",378137,380073,1937,"Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall","no"]
["YOR097C",null,57,15,"+",506945,507817,873,"Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen; YOR097C is not an essential gene","no"]
["YBR067C","TIP1",58,2,"+",372119,372543,425,"Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins","yes"]
["YKL127W","PGM1",66,11,"-",203832,204600,769,"Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism","no"]
["YGL021W","ALK1",68,7,"-",454935,455087,"NA","Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins","yes"]
["YPR135W","CTF4",74,16,"-",799783,800391,609,"Chromatin-associated protein, required for sister chromatid cohesion; interacts with DNA polymerase alpha (Pol1p) and may link DNA synthesis to sister chromatid cohesion","yes"]
["YBR180W","DTR1",75,2,"-",590100,591348,1249,"Multidrug resistance dityrosine transporter of the major facilitator superfamily, essential for spore wall synthesis, facilitates the translocation of bisformyl dityrosine through the prospore membrane","no"]
["YPR194C, YPR195C","OPT2",78,16,"+",924291,928339,4049,"Oligopeptide transporter; member of the OPT family, with potential orthologs in S. pombe and C. albicans","no"]
["YJL078C","PRY3",80,10,"+",291913,293537,1625,"Protein of unknown function, has similarity to Pry1p and Pry2p and to the plant PR-1 class of pathogen related proteins","yes"]
["YNL300W",null,82,14,"-",65757,66037,281,"Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid","yes"]
["YMR181C",null,82,13,"+",623585,625281,"NA","Protein of unknown function; mRNA transcribed as part of a bicistronic transcript with a predicted transcriptional repressor RGM1/YMR182C; mRNA is destroyed by nonsense-mediated decay (NMD); YMR181C is not an essential gene","no"]

{"sheet":"43 non-periodic antisense","index":1,"n_rows":44,"n_cols":8,"rows_kept":44,"flags":["formulas_cached_only"]}
["opposite sense transcript","gene name","chr","strand","start","end","length","(SGD description) function of the sense counterpart"]
["YBR086C","IST2",2,"+",420247,420615,369,"Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells"]
["YBR092C","PHO3",2,"+",427911,428975,1065,"Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin"]
["YBL029W",null,2,"-",166467,166947,481,"Non-essential protein of unknown function"]
["YDR326C","YSP2",4,"+",1123955,1124531,577,"Protein involved in programmed cell death; mutant shows resistance to cell death induced by amiodarone or intracellular acidification"]
["YDL074C","BRE1",4,"+",323929,324393,465,"E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on K4 and K79), contains RING finger domain"]
["YDR501W","PLM2",4,"-",1451311,1452815,1505,"Protein required for partitioning of the 2-micron plasmid"]
["YER158C",null,5,"+",490073,491057,985,"Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p"]
["YGL200C","EMP24",7,"+",122811,123107,297,"Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport"]
["YGL037C","PNC1",7,"+",427435,427955,521,"Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span"]
["YGL028C","SCW11",7,"+",442115,442955,841,"Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p"]
["YGR189C","CRH1",7,"+",877483,877811,329,"Putative chitin transglycosidase, cell wall protein that functions in the transfer of chitin to beta(1-6)glucan; localizes to sites of polarized growth; expression is induced under cell wall stress conditions"]
["YGR041W","BUD9",7,"-",577383,579287,1905,"Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the distal pole"]
["YGR145W","ENP2",7,"-",783071,783311,241,"Essential nucleolar protein of unknown function; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p"]
["YHR061C","GIC1",8,"+",221784,222712,929,"Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain"]
["YHR110W","ERP5",8,"-",332388,332580,193,"Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport"]
["YHR143W","DSE2",8,"-",385749,386461,713,"Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP"]
["YIL011W","TIR3",9,"-",333653,334517,865,"Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth"]
["YJL079C","PRY1",10,"+",289873,290665,793,"Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins"]
["YJL196C","ELO1",10,"+",67865,68689,825,"Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids"]
["YJL105W","SET4",10,"-",226221,226557,337,"Protein of unknown function, contains a SET domain"]
["YJL051W","IRC8",10,"-",340493,342141,1649,"Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent transport system; mRNA is cell cycle regulated via Fkh2p, peaking in G2/M phase; null mutant displays increased levels of spontaneous Rad52p foc"]
["YKL164C","PIR1",11,"+",141764,142852,1089,"O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle"]
["YLR042C",null,12,"+",230041,230489,449,"Protein of unknown function; localizes to the cytoplasm; YLL042C is not an essential gene"]
["YLR121C","YPS3",12,"+",388889,390409,1521,"Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor"]
["YLR194C",null,12,"+",540785,541601,817,"Structural constituent of the cell wall attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress"]
["YLR286C","CTS1",12,"+",709529,709665,137,"Endochitinase, required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p"]
["YLR342W","FKS1",12,"-",809779,810203,425,"Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling"]
["YLR342W",null,12,"-",811115,811467,353]
["YLR342W",null,12,"-",812923,813707,785]
["YML125C","PGA3",13,"+",20777,21761,985,"Essential protein required for maturation of Gas1p and Pho8p, proposed to be involved in protein trafficking; GFP-fusion protein localizes to the endoplasmic reticulum; null mutants have a cell separation defect"]
["YMR132C","JLP2",13,"+",535009,535553,545,"Protein of unknown function, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)"]
["YMR011W","HXT2",13,"-",288389,289685,1297,"High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose"]
["YMR251W","GTO3",13,"-",772749,773573,825,"Omega class glutathione transferase; putative cytosolic localization"]
["YNL024C",null,14,"+",587490,588242,753,"Putative protein of unknown function with seven beta-strand methyltransferase motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL024C is not an essential gene"]
["YNR067C","DSE4",14,"+",755362,756234,873,"Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mothe"]
["YNL072W","RNH201",14,"-",490325,491173,849,"Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis; cooperates with Rad27p nuclease; homolog of mammalian RNAse HI (the S. cerevisiae homolog of mammalian RNAse HII is RNH1)"]
["YNL046W",null,14,"-",542214,542798,585,"Putative protein of unknown function; expression depends on Swi5p; GFP-fusion protein localizes to the endoplasmic reticulum; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)"]
["YNR004W",null,14,"-",635894,636718,825,"Putative protein of unknown function; haploid disruptant exhibits slow growth rate on glucose-minimal medium at 15 C"]
["YOR008C","SLG1",15,"+",341273,341649,377,"Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in maintenance of cell wall integrity; involved in organization of the actin cytoskeleton; secretory pathway Wsc1p is required for the arrest of secretion response"]
["YOL154W","ZPS1",15,"-",34581,35629,1049,"Putative GPI-anchored protein; transcription is induced under low-zinc conditions, as mediated by the Zap1p transcription factor, and at alkaline pH"]
["YOR274W","MOD5",15,"-",837661,838165,505,"Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms"]
["YPL163C","SVS1",16,"+",242369,242457,89,"Cell wall and vacuolar protein, required for wild-type resistance to vanadate"]
["YPL241C","CIN2",16,"+",95457,96401,945,"GTPase-activating protein (GAP) for Cin4p; tubulin folding factor C involved in beta-tubulin (Tub2p) folding; mutants display increased chromosome loss and benomyl sensitivity; deletion complemented by human GAP, retinitis pigmentosa 2"]

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