{"text_format":"3","workbook":"xls","n_sheets":2,"sheets":["ClueGO Results NodeAttributeTab","ClueGO Results Functional Group"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"ClueGO Results NodeAttributeTab","index":0,"n_rows":35,"n_cols":18,"rows_kept":35,"flags":["formulas_cached_only"]}
["GOID","Ontology Source","GOTerm","GOLevels","GOGroups","Nr. Genes","% Associated Genes","Term PValue","Term PValue Corrected with Bonferroni step down","Group PValue","Group PValue Corrected with Bonferroni step down","Associated Genes Found","All Associated Genes","OverViewTerm","Genes Cluster #1","%Genes Cluster #1","Genes Cluster #2","%Genes Cluster #2"]
["KEGG:00750","KEGG_10.02.2016","Vitamin B6 metabolism","[-1]","[Group22]",2,33.333332,0.00913796180795489,0.0274138854238646,"{Group22=0.009137961807954896}","{Group22=0.03655184723181958}","[PNPO, PSAT1]","[AOX1, PDXK, PDXP, PHOSPHO2, PNPO, PSAT1]","FALSE","[]",0,"[PNPO, PSAT1]",100]
["GO:0003051","GO_BiologicalProcess-GOA_09.02.2016_16h18","angiotensin-mediated drinking behavior","[4, 6, 7, 8, 9, 10, 12]","[Group19]",2,50,0.00378182612644842,0.026472782885139,"{Group19=0.0061964961468069435}","{Group19=0.030982480734034718}","[ACE2, AGXT]","[ACE2, AGT, AGXT, TACR1]","TRUE","[]",0,"[ACE2, AGXT]",100]
["GO:0003331","GO_BiologicalProcess-GOA_09.02.2016_16h18","positive regulation of extracellular matrix constituent secretion","[4, 5, 6, 7, 8, 9]","[Group0]",2,50,0.00378182612644842,0.026472782885139,"{Group0=0.003781826126448429}","{Group0=0.03025460901158743}","[AGXT, CPB2]","[AGT, AGXT, CPB2, RGCC]","TRUE","[]",0,"[AGXT, CPB2]",100]
["KEGG:04610","KEGG_10.02.2016","Complement and coagulation cascades","[-1]","[Group23]",14,20.289856,{"v":1.81323866026516e-09,"d":"1.81E-09"},{"v":3.2638295884773e-08,"d":"3.26E-08"},"{Group23=1.8132386602651683E-9}","{Group23=3.263829588477303E-8}","[A2M, C4BPA, C5, C7, C8G, C9, CFB, CPB2, F2, F5, PLG, PROC, SERPINA1, SERPINC1]","[A2M, BDKRB1, BDKRB2, C1QA, C1QB, C1QC, C1R, C1S, C2, C3, C3AR1, C4A, C4B, C4BPA, C4BPB, C5, C5AR1, C6, C7, C8A, C8B, C8G, C9, CD46, CD55, CD59, CFB, CFD, CFH, CFI, CPB2, CR1, CR2, F10, F11, F12, F13A1, F13B, F2, F2R, F3, F5, F7, F8, F9, FGA, FGB, FGG, KLKB1, KNG1, MASP1, MASP2, MBL2, PLAT, PLAU, PLAUR, PLG, PROC, PROS1, SERPINA1, SERPINA5, SERPINC1, SERPIND1, SERPINE1, SERPINF2, SERPING1, TFPI, THBD, VWF]","TRUE","[]",0,"[A2M, C4BPA, C5, C7, C8G, C9, CFB, CPB2, F2, F5, PLG, PROC, SERPINA1, SERPINC1]",100]
["GO:0006559","GO_BiologicalProcess-GOA_09.02.2016_16h18","L-phenylalanine catabolic process","[6, 7, 8, 9, 10, 11]","[Group9]",3,23.076923,0.00392290672745623,0.0235374403647374,"{Group9=0.003922906727456239}","{Group9=0.027460347092193672}","[ATAT1, HPD, PCBD1]","[ASRGL1, ATAT1, CCBL1, FAH, FANCA, GSTZ1, HGD, HPD, IL4I1, PAH, PCBD1, QDPR, TAT]","TRUE","[]",0,"[ATAT1, HPD, PCBD1]",100]
["GO:0008615","GO_BiologicalProcess-GOA_09.02.2016_16h18","pyridoxine biosynthetic process","[5, 6, 7, 8]","[Group22]",2,100,{"v":0.000652238430495829,"d":"6.52E-04"},0.00652238430495828,"{Group22=0.009137961807954896}","{Group22=0.03655184723181958}","[PNPO, PSAT1]","[PNPO, PSAT1]","TRUE","[]",0,"[PNPO, PSAT1]",100]
["GO:0010535","GO_BiologicalProcess-GOA_09.02.2016_16h18","positive regulation of activation of JAK2 kinase activity","[9, 10, 11, 12, 13, 14, 15]","[Group24]",2,28.571428,0.0125778191302011,0.0251556382604023,"{Group24=0.012577819130201184}","{Group24=0.03773345739060355}","[AGXT, CCL5]","[AGT, AGXT, CCL5, GH1, IL12B, IL23A, IL23R]","TRUE","[]",0,"[AGXT, CCL5]",100]
["GO:0010693","GO_BiologicalProcess-GOA_09.02.2016_16h18","negative regulation of alkaline phosphatase activity","[6, 7, 8, 9, 10, 11]","[Group25]",2,50,0.00378182612644842,0.026472782885139,"{Group25=0.003781826126448429}","{Group25=0.03025460901158743}","[HPN, TGFB2]","[HPN, SEMA4D, TGFB2, TNF]","TRUE","[]",0,"[HPN, TGFB2]",100]
["GO:0010873","GO_BiologicalProcess-GOA_09.02.2016_16h18","positive regulation of cholesterol esterification","[4, 5, 6, 7, 8, 9, 10]","[Group26]",5,50,{"v":2.42555872286214e-06,"d":"2.43E-06"},{"v":4.12344982886564e-05,"d":"4.12E-05"},"{Group26=2.4255587228621437E-6}","{Group26=4.123449828865644E-5}","[AGXT, APOA2, APOA4, APOA5, APOE]","[AGT, AGTR1, AGXT, APOA1, APOA2, APOA4, APOA5, APOC1, APOE, LPAL2]","TRUE","[]",0,"[AGXT, APOA2, APOA4, APOA5, APOE]",100]
["GO:0010896","GO_BiologicalProcess-GOA_09.02.2016_16h18","regulation of triglyceride catabolic process","[5, 6, 7, 8, 9]","[Group15]",3,25,0.00307556963081677,0.0246045570465341,"{Group15=0.013697199113965273}","{Group15=0.027394398227930546}","[APOA4, APOA5, APOC3]","[AADAC, ABHD5, APOA1, APOA4, APOA5, APOC2, APOC3, APOH, GPLD1, PIK3CG, PLIN5, PNPLA2]","TRUE","[]",0,"[APOA4, APOA5, APOC3]",100]
["GO:0010901","GO_BiologicalProcess-GOA_09.02.2016_16h18","regulation of very-low-density lipoprotein particle remodeling","[3, 4, 5, 6, 7, 9]","[Group27]",3,50,{"v":0.00031356482348314,"d":"3.14E-04"},0.00407634270528082,"{Group27=3.1356482348314003E-4}","{Group27=0.00407634270528082}","[APOA2, APOA5, APOC3]","[APOA1, APOA2, APOA5, APOC2, APOC3, LPAL2]","TRUE","[]",0,"[APOA2, APOA5, APOC3]",100]
["GO:0015091","GO_MolecularFunction-GOA_09.02.2016_16h18","ferric iron transmembrane transporter activity","[8, 10]","[Group28]",2,50,0.00378182612644842,0.026472782885139,"{Group28=0.003781826126448429}","{Group28=0.03025460901158743}","[TF, TFRC]","[F3, SLC11A2, TF, TFRC]","TRUE","[]",0,"[TF, TFRC]",100]
["GO:0019074","GO_BiologicalProcess-GOA_09.02.2016_16h18","viral RNA genome packaging","[5, 6, 7, 8]","[Group1]",2,40,0.00619649614680694,0.0247859845872277,"{Group1=0.0061964961468069435}","{Group1=0.030982480734034718}","[PC, PROC]","[DDX6, KRT17, PC, PODXL, PROC]","TRUE","[]",0,"[PC, PROC]",100]
["GO:0019265","GO_BiologicalProcess-GOA_09.02.2016_16h18","glycine biosynthetic process, by transamination of glyoxylate","[8, 9, 10, 11, 12]","[Group12]",2,100,{"v":0.000652238430495829,"d":"6.52E-04"},0.00652238430495828,"{Group12=0.0061964961468069435}","{Group12=0.030982480734034718}","[AGXT, AGXT2]","[AGXT, AGXT2]","TRUE","[]",0,"[AGXT, AGXT2]",100]
["GO:0019556","GO_BiologicalProcess-GOA_09.02.2016_16h18","histidine catabolic process to glutamate and formamide","[5, 6, 7, 8, 9, 10, 11]","[Group2]",2,50,0.00378182612644842,0.026472782885139,"{Group2=0.003781826126448429}","{Group2=0.03025460901158743}","[AMDHD1, UROC1]","[AMDHD1, FTCD, HAL, UROC1]","TRUE","[]",0,"[AMDHD1, UROC1]",100]
["GO:0019557","GO_BiologicalProcess-GOA_09.02.2016_16h18","histidine catabolic process to glutamate and formate","[7, 8, 9, 10, 11]","[Group2]",2,50,0.00378182612644842,0.026472782885139,"{Group2=0.003781826126448429}","{Group2=0.03025460901158743}","[AMDHD1, UROC1]","[AMDHD1, FTCD, HAL, UROC1]","FALSE","[]",0,"[AMDHD1, UROC1]",100]
["GO:0019836","GO_BiologicalProcess-GOA_09.02.2016_16h18","hemolysis by symbiont of host erythrocytes","[5, 6, 8, 9]","[Group3]",3,100,{"v":1.66088475618519e-05,"d":"1.66E-05"},{"v":0.000249132713427778,"d":"2.49E-04"},"{Group3=1.6608847561851924E-5}","{Group3=2.491327134277789E-4}","[AKR1C1, ALB, C9]","[AKR1C1, ALB, C9]","TRUE","[]",0,"[AKR1C1, ALB, C9]",100]
["GO:0030299","GO_BiologicalProcess-GOA_09.02.2016_16h18","intestinal cholesterol absorption","[5, 6, 7, 8]","[Group4]",4,26.666666,{"v":0.000460290210267594,"d":"4.60E-04"},0.00552348252321113,"{Group4=4.602902102675948E-4}","{Group4=0.005523482523211137}","[AKR1C1, APOA2, APOA4, APOA5]","[ABCG5, ABCG8, AKR1C1, APOA1, APOA2, APOA4, APOA5, CD36, CEL, LDLR, LEP, LPAL2, NPC1L1, PNLIP, SOAT2]","TRUE","[]",0,"[AKR1C1, APOA2, APOA4, APOA5]",100]
["GO:0030502","GO_BiologicalProcess-GOA_09.02.2016_16h18","negative regulation of bone mineralization","[4, 5, 6, 7, 8, 9]","[Group5]",4,25,{"v":0.000601381894294611,"d":"6.01E-04"},0.00661520083724073,"{Group5=6.013818942946118E-4}","{Group5=0.00661520083724073}","[AHSG, FAM101A, PTK2B, SOX9]","[AHSG, BCOR, CCL3, CCR1, ECM1, FAM101A, FAM101B, FGF23, GATA1, GREM1, HIF1A, MEPE, PTK2B, SOX9, SRGN, STATH]","TRUE","[]",0,"[AHSG, FAM101A, PTK2B, SOX9]",100]
["GO:0030868","GO_CellularComponent-GOA_09.02.2016_16h18","smooth endoplasmic reticulum membrane","[3, 4, 5, 6, 7, 8, 9, 10]","[Group6]",2,25,0.0164887671160308,0.0164887671160308,"{Group6=0.01648876711603083}","{Group6=0.01648876711603083}","[ALDOB, HSD3B1]","[ALDOB, FTCD, HSD3B1, HSD3B2, SEC23A, STX17, SVIP, TTYH1]","TRUE","[]",0,"[ALDOB, HSD3B1]",100]
["GO:0032375","GO_BiologicalProcess-GOA_09.02.2016_16h18","negative regulation of cholesterol transport","[5, 6, 7, 8, 9]","[Group7]",3,23.076923,0.00392290672745623,0.0235374403647374,"{Group7=0.003922906727456239}","{Group7=0.027460347092193672}","[APOA2, APOC3, APOE]","[ABCG5, ABCG8, APOA2, APOC1, APOC2, APOC3, APOE, EGF, LPAL2, NFKB1, PLA2G10, SHH, SREBF2]","TRUE","[]",0,"[APOA2, APOC3, APOE]",100]
["GO:0032489","GO_BiologicalProcess-GOA_09.02.2016_16h18","regulation of Cdc42 protein signal transduction","[8, 9, 10]","[Group8]",2,50,0.00378182612644842,0.026472782885139,"{Group8=0.003781826126448429}","{Group8=0.03025460901158743}","[APOC3, APOE]","[ABCA1, APOA1, APOC3, APOE]","TRUE","[]",0,"[APOC3, APOE]",100]
["GO:0032972","GO_BiologicalProcess-GOA_09.02.2016_16h18","regulation of muscle filament sliding speed","[3, 6, 7, 8, 9]","[Group10]",2,66.666664,0.00192349759639162,0.0173114783675246,"{Group10=0.0019234975963916285}","{Group10=0.017311478367524655}","[TNNI3, TNNT2]","[TNNC1, TNNI3, TNNT2]","TRUE","[]",0,"[TNNI3, TNNT2]",100]
["GO:0034372","GO_BiologicalProcess-GOA_09.02.2016_16h18","very-low-density lipoprotein particle remodeling","[5, 6, 8]","[Group11]",5,38.46154,{"v":1.16227190396149e-05,"d":"1.16E-05"},{"v":0.000185963504633839,"d":"1.86E-04"},"{Group11=1.1622719039614999E-5}","{Group11=1.8596350463383999E-4}","[APOA2, APOA4, APOA5, APOC3, APOE]","[APOA1, APOA2, APOA4, APOA5, APOC2, APOC3, APOE, CETP, LCAT, LCP1, LIPC, LPAL2, LPL]","TRUE","[]",0,"[APOA2, APOA4, APOA5, APOC3, APOE]",100]
["GO:0042853","GO_BiologicalProcess-GOA_09.02.2016_16h18","L-alanine catabolic process","[8, 9, 10, 11, 12]","[Group12]",2,40,0.00619649614680694,0.0247859845872277,"{Group12=0.0061964961468069435}","{Group12=0.030982480734034718}","[AGXT, AGXT2]","[AGXT, AGXT2, DPAGT1, GPT, GPT2]","FALSE","[]",0,"[AGXT, AGXT2]",100]
["GO:0044794","GO_BiologicalProcess-GOA_09.02.2016_16h18","positive regulation by host of viral process","[4, 5, 6, 7]","[Group13]",3,20,0.00600847986478804,0.0300423993239402,"{Group13=0.006008479864788048}","{Group13=0.03605087918872829}","[APOE, PC, PROC]","[APOE, CAV2, CFL1, KRT17, PC, PODXL, PPIB, PROC, STOM, TBC1D20, VAPA, VAPB, VPS72, YTHDC2, ZNF502]","TRUE","[]",0,"[APOE, PC, PROC]",100]
["GO:0046533","GO_BiologicalProcess-GOA_09.02.2016_16h18","negative regulation of photoreceptor cell differentiation","[6, 7, 8, 9, 10, 11]","[Group14]",2,40,0.00619649614680694,0.0247859845872277,"{Group14=0.0061964961468069435}","{Group14=0.030982480734034718}","[CASZ1, SOX9]","[CASZ1, CNTF, NOTCH1, SOX8, SOX9]","TRUE","[]",0,"[CASZ1, SOX9]",100]
["GO:0051004","GO_BiologicalProcess-GOA_09.02.2016_16h18","regulation of lipoprotein lipase activity","[6, 7]","[Group15]",3,20,0.00600847986478804,0.0300423993239402,"{Group15=0.013697199113965273}","{Group15=0.027394398227930546}","[APOA4, APOA5, APOC3]","[ABHD5, ANGPTL3, ANGPTL4, APOA1, APOA4, APOA5, APOC1, APOC2, APOC3, APOH, GPIHBP1, LMF1, NR1H2, NR1H3, SORT1]","FALSE","[]",0,"[APOA4, APOA5, APOC3]",100]
["GO:0051918","GO_BiologicalProcess-GOA_09.02.2016_16h18","negative regulation of fibrinolysis","[2, 3, 4, 5, 6, 7, 8, 9, 10, 11]","[Group16]",4,36.363636,{"v":0.000120717603681119,"d":"1.21E-04"},0.00169004645153566,"{Group16=1.2071760368111918E-4}","{Group16=0.0016900464515356684}","[CPB2, F2, HRG, PLG]","[APOH, CPB2, F2, HRG, NRG1, PLG, SERPINE1, SERPINF2, THBD, THBS1, USF1]","TRUE","[]",0,"[CPB2, F2, HRG, PLG]",100]
["GO:0060734","GO_BiologicalProcess-GOA_09.02.2016_16h18","regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation","[4, 5, 6, 7, 8, 9, 10, 11, 12, 13]","[Group17]",2,100,{"v":0.000652238430495829,"d":"6.52E-04"},0.00652238430495828,"{Group17=6.52238430495829E-4}","{Group17=0.0065223843049582895}","[EIF2AK3, PPP1R15A]","[EIF2AK3, PPP1R15A]","TRUE","[]",0,"[EIF2AK3, PPP1R15A]",100]
["GO:1902430","GO_BiologicalProcess-GOA_09.02.2016_16h18","negative regulation of beta-amyloid formation","[5, 6, 7, 8, 9]","[Group18]",2,28.571428,0.0125778191302011,0.0251556382604023,"{Group18=0.012577819130201184}","{Group18=0.03773345739060355}","[APOE, SORL1]","[ABCA7, APEX1, APOE, CLU, HAP1, OLFM1, SORL1]","TRUE","[]",0,"[APOE, SORL1]",100]
["GO:1903598","GO_BiologicalProcess-GOA_09.02.2016_16h18","positive regulation of gap junction assembly","[4, 5, 6, 7, 8]","[Group19]",2,50,0.00378182612644842,0.026472782885139,"{Group19=0.0061964961468069435}","{Group19=0.030982480734034718}","[ACE2, AGXT]","[ACE2, AGT, AGXT, CAV1]","FALSE","[]",0,"[ACE2, AGXT]",100]
["GO:2000323","GO_BiologicalProcess-GOA_09.02.2016_16h18","negative regulation of glucocorticoid receptor signaling pathway","[5, 6, 7, 8, 9, 10]","[Group20]",3,50,{"v":0.00031356482348314,"d":"3.14E-04"},0.00407634270528082,"{Group20=3.1356482348314003E-4}","{Group20=0.00407634270528082}","[ARNTL, CRY2, PER1]","[ARNTL, CLOCK, CRY1, CRY2, PER1, PHB]","TRUE","[CRY2, PER1]",66.6666666666666,"[ARNTL]",33.3333333333333]
["GO:2000741","GO_BiologicalProcess-GOA_09.02.2016_16h18","positive regulation of mesenchymal stem cell differentiation","[5, 6, 7, 8]","[Group21]",2,40,0.00619649614680694,0.0247859845872277,"{Group21=0.0061964961468069435}","{Group21=0.030982480734034718}","[LTBP2, SOX9]","[LTBP2, LTBP3, SOX5, SOX6, SOX9]","TRUE","[]",0,"[LTBP2, SOX9]",100]

{"sheet":"ClueGO Results Functional Group","index":1,"n_rows":30,"n_cols":3,"rows_kept":30,"flags":["formulas_cached_only"]}
["Function","Groups","Group Genes"]
["Complement and coagulation cascades","Group23","A2M|C4BPA|C5|C7|C8G|C9|CFB|CPB2|F2|F5|PLG|PROC|SERPINA1|SERPINC1"]
["L-phenylalanine catabolic process","Group9","ATAT1|HPD|PCBD1"]
["angiotensin-mediated drinking behavior","Group19","ACE2|AGXT"]
["ferric iron transmembrane transporter activity","Group28","TF|TFRC"]
["glycine biosynthetic process, by transamination of glyoxylate","Group12","AGXT|AGXT2"]
["hemolysis by symbiont of host erythrocytes","Group3","AKR1C1|ALB|C9"]
["histidine catabolic process to glutamate and formamide","Group2","AMDHD1|UROC1"]
["intestinal cholesterol absorption","Group4","AKR1C1|APOA2|APOA4|APOA5"]
["negative regulation of alkaline phosphatase activity","Group25","HPN|TGFB2"]
["negative regulation of beta-amyloid formation","Group18","APOE|SORL1"]
["negative regulation of bone mineralization","Group5","AHSG|FAM101A|PTK2B|SOX9"]
["negative regulation of cholesterol transport","Group7","APOA2|APOC3|APOE"]
["negative regulation of fibrinolysis","Group16","CPB2|F2|HRG|PLG"]
["negative regulation of glucocorticoid receptor signaling pathway","Group20","ARNTL|CRY2|PER1"]
["negative regulation of photoreceptor cell differentiation","Group14","CASZ1|SOX9"]
["positive regulation by host of viral process","Group13","APOE|PC|PROC"]
["positive regulation of activation of JAK2 kinase activity","Group24","AGXT|CCL5"]
["positive regulation of cholesterol esterification","Group26","AGXT|APOA2|APOA4|APOA5|APOE"]
["positive regulation of extracellular matrix constituent secretion","Group0","AGXT|CPB2"]
["positive regulation of mesenchymal stem cell differentiation","Group21","LTBP2|SOX9"]
["pyridoxine biosynthetic process","Group22","PNPO|PSAT1"]
["regulation of Cdc42 protein signal transduction","Group8","APOC3|APOE"]
["regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation","Group17","EIF2AK3|PPP1R15A"]
["regulation of muscle filament sliding speed","Group10","TNNI3|TNNT2"]
["regulation of triglyceride catabolic process","Group15","APOA4|APOA5|APOC3"]
["regulation of very-low-density lipoprotein particle remodeling","Group27","APOA2|APOA5|APOC3"]
["smooth endoplasmic reticulum membrane","Group6","ALDOB|HSD3B1"]
["very-low-density lipoprotein particle remodeling","Group11","APOA2|APOA4|APOA5|APOC3|APOE"]
["viral RNA genome packaging","Group1","PC|PROC"]