gene_name #ID control1_Count control2_Count control3_Count ste-1_Count ste-2_Count ste-3_Count control1_FPKM control2_FPKM control3_FPKM ste-1_FPKM ste-2_FPKM ste-3_FPKM FDR log2FC regulated COG_class COG_class_annotation GO_annotation KEGG_annotation KEGG_pathway_annotation KOG_class KOG_class_annotation Pfam_annotation Swiss-Prot_annotation eggNOG_class eggNOG_class_annotation NR_annotation K10D11.2 gene20337 120 110 99 1340 1152 1275 7.655911343 6.50081003 6.1593368 80.60072321355 68.10440252055 75.89881100332 2.9107439646879e-60 3.50302767865796 up -- -- -- -- -- -- -- CUB-like domain Protein K10D11.2 {ECO:0000313|EMBL:CAB03526.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein K10D11.2 [Caenorhabditis elegans] Y11D7A.10 gene18855 1091 1430 952 3630 2712 3985 726.774 863.176 643.321 2384.27157 2164.90694 2949.7471 8.17860547666124e-08 1.55892098466748 up -- -- -- -- -- -- -- -- Protein Y11D7A.10, isoform a {ECO:0000313|EMBL:CAB63344.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y11D7A.10, isoform b [Caenorhabditis elegans] Y18D10A.23 gene3633 798 725 440 310 288 285 29.6963095 26.20266322885 15.959688143 11.11193977 10.993694053 10.2308315062 0.00570843065420146 -1.16615924411714 down -- -- Biological Process: amino acid transmembrane transport (GO:0003333);; -- -- [E] Amino acid transport and metabolism Transmembrane amino acid transporter protein;; Tryptophan/tyrosine permease family Protein Y18D10A.23 {ECO:0000313|EMBL:CAA22315.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein Y18D10A.23 [Caenorhabditis elegans] fat-4 gene19074 5771 5862 6119 14969 13537 15258 266.4555035394 264.470683124 275.63824908 667.0083034419 612.4589109944 663.716066 1.85500541994813e-12 1.28747322865898 up [I] Lipid transport and metabolism Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Fatty acid desaturase CRE-FAT-4 protein {ECO:0000313|EMBL:EFP04845.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only Protein FAT-4, isoform a [Caenorhabditis elegans] C04G2.9 gene19232 480 575 801 249 314 311 25.778 30.5747 42.8827 13.0154 16.1117 16.0866 0.00570843065420146 -1.10078971176257 down -- -- -- -- -- -- -- Cytosolic motility protein Protein C04G2.9 {ECO:0000313|EMBL:CAA94678.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein C04G2.9 [Caenorhabditis elegans] ilys-5 gene42918 283 191 273 74 65 44 120.0631156846 77.24436557195 108.9724126845 31.1607487436 33.22408710433 18.64506273062 1.32842705086128e-09 -2.04502883109071 down -- -- Molecular Function: lysozyme activity (GO:0003796);; -- -- -- -- Destabilase Protein ILYS-5, isoform a {ECO:0000313|EMBL:CCD64578.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein ILYS-5, isoform a [Caenorhabditis elegans] mltn-11 gene39267 82 70 47 28 26 21 2.159359 1.977224 1.237831 0.7115751353 0.6616570136 0.656234 0.000632910668699916 -1.42183963326505 down -- -- -- -- -- -- -- Moulting cycle Protein MLTN-11 {ECO:0000313|EMBL:CAB05642.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein MLTN-11 [Caenorhabditis elegans] T10H10.2 gene41337 616 604 420 1206 1271 1378 20.6401 19.9158 13.7816 39.3863 40.1536 44.1754 8.41487728641214e-10 1.21968849361661 up [OC] Posttranslational modification, protein turnover, chaperones;; Energy production and conversion Molecular Function: thiol oxidase activity (GO:0016972);; Biological Process: cell redox homeostasis (GO:0045454);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [D] Cell cycle control, cell division, chromosome partitioning Erv1 / Alr family;; Thioredoxin Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein T10H10.2 [Caenorhabditis elegans] clec-60 gene8007 1677 1078 1069 4530 4130 4228 74.447 46.80712 47.3238 193.9175 184.823 188.4734 1.33388475557852e-22 1.73818510959418 up -- -- -- -- -- -- -- von Willebrand factor type A domain Protein CLEC-60 {ECO:0000313|EMBL:CAA88985.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein CLEC-60 [Caenorhabditis elegans] ddo-2 gene35332 400 349 647 1476 1438 1703 22.64718 18.211687 36.39994 80.6158 78.7157 93.328 8.94406474586163e-18 1.71033998796657 up [E] Amino acid transport and metabolism Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00272|0|cbr:CBG04460|Hypothetical protein CBG04460; K00272 D-aspartate oxidase [EC:1.4.3.1] (A) Alanine, aspartate and glutamate metabolism (ko00250);; Peroxisome (ko04146) [E] Amino acid transport and metabolism FAD dependent oxidoreductase CRE-DDO-2 protein {ECO:0000313|EMBL:EFP00640.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only Protein DDO-2, isoform a [Caenorhabditis elegans] D1086.3 gene38148 1339 1199 1028 686 526 583 106.537491 98.02947 79.735931 56.4495 54.748594 51.240828 8.17229333146175e-07 -1.00472579521209 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein D1086.3 {ECO:0000313|EMBL:CAB04018.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein D1086.3 [Caenorhabditis elegans] gst-9 gene5876 48 60 67 129 111 158 7.40478 8.85869 9.98309 19.8948 18.1931 26.0632 0.000400868783855447 1.17132677641135 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT52651.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 G Carbohydrate transport and metabolism Protein GST-9 [Caenorhabditis elegans] T03E6.9 gene39248 589 599 554 1577 2018 1637 13.880470026283 12.5594486311835 12.4228056209346 33.6079852000465 46.32162043 39.301197722569 1.91779288685561e-16 1.57287102289057 up -- -- -- -- -- -- -- Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Sri Protein T03E6.9 {ECO:0000313|EMBL:CAM84813.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein T03E6.9 [Caenorhabditis elegans] F55F3.2 gene45496 333 356 213 155 130 132 10.63249541 11.6209062 6.931398589 5.149775 4.2213766 4.32176043 0.00204158443834745 -1.12661371288435 down [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein F55F3.2, isoform b {ECO:0000313|EMBL:CAD44141.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein F55F3.2, isoform b [Caenorhabditis elegans] cpt-3 gene9905 72 58 8 106 117 144 1.756242 1.414 0.203312 2.52989 2.857906 3.48461 0.00532385013602514 1.39918860474664 up -- -- Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; -- -- [I] Lipid transport and metabolism Choline/Carnitine o-acyltransferase Protein CPT-3 {ECO:0000313|EMBL:CCD67073.1} OS=Caenorhabditis elegans PE=4 SV=3 J Translation, ribosomal structure and biogenesis Protein CPT-3 [Caenorhabditis elegans] Y39B6A.30 gene40142 121 185 194 67 72 83 1.5943 2.56314 2.66093 0.955849 1.02555 1.29601 0.000656905532543615 -1.18501544053022 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- -- -- Protein-tyrosine phosphatase;; Domain of unknown function;; Dual specificity phosphatase, catalytic domain Protein Y39B6A.30 {ECO:0000313|EMBL:CAD31825.2} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein Y39B6A.30 [Caenorhabditis elegans] nhr-62 gene2629 645 655 634 1375 1343 1263 23.3007362992454 23.9038812356766 23.91428427 52.073057015 51.58843485 50.9464419584835 2.96347653343908e-07 1.02734243774234 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Nuclear receptor NHR-62 {ECO:0000313|EMBL:AAG15163.1} (Fragment) OS=Caenorhabditis elegans PE=2 SV=1 K Transcription Protein NHR-62, isoform a [Caenorhabditis elegans] T05F1.9 gene2557 150 139 121 60 51 42 10.5193 9.87411 8.52998 4.45509 3.86374 3.35394 8.2735505311437e-06 -1.43661463713154 down -- -- -- -- -- -- -- -- Protein T05F1.9 {ECO:0000313|EMBL:CAB04693.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein T05F1.9 [Caenorhabditis elegans] C17H12.3 gene17794 107 181 175 80 63 85 4.996 8.262053826 8.0908990321 3.694425276 3.042067 4.0394460286 0.0090403945705065 -1.0357860311138 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain Protein C17H12.3 {ECO:0000313|EMBL:CCD64993.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C17H12.3 [Caenorhabditis elegans] math-10 gene4837 3 2 3 123 134 130 0.1054622 0.209159219423 0.27884718896 6.95178 7.0352 7.53809 1.59273564047904e-33 5.58114580567799 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- MATH domain Protein MATH-10 {ECO:0000313|EMBL:CCD64677.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein MATH-10 [Caenorhabditis elegans] F49H6.5 gene39422 144 134 83 390 399 438 8.778595326 8.2414899317 5.38151 24.578302721 26.454221836 29.9668353261 4.04317928131413e-13 1.75179052516811 up [H] Coenzyme transport and metabolism Molecular Function: catalytic activity (GO:0003824);; Biological Process: Mo-molybdopterin cofactor biosynthetic process (GO:0006777);; Cellular Component: molybdopterin synthase complex (GO:0019008);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; Molecular Function: 4 iron, 4 sulfur cluster binding (GO:0051539);; K03639|0|cel:CELE_F49H6.5|F49H6.5; Protein F49H6.5; K03639 cyclic pyranopterin phosphate synthase [EC:4.1.99.18] (A) Folate biosynthesis (ko00790);; Sulfur relay system (ko04122) [H] Coenzyme transport and metabolism Molybdenum Cofactor Synthesis C;; Radical SAM superfamily;; 4Fe-4S single cluster domain;; 4Fe-4S single cluster domain Protein F49H6.5 {ECO:0000313|EMBL:CAB04440.1} OS=Caenorhabditis elegans PE=3 SV=1 H Coenzyme transport and metabolism Protein F49H6.5 [Caenorhabditis elegans] Y37A1A.2 gene21439 162 170 243 419 388 630 7.84857 7.861586 11.87315 20.48523 17.22651 31.28526 0.00287663314887312 1.30702074109177 up -- -- -- -- -- [S] Function unknown Ion channel regulatory protein UNC-93;; Major Facilitator Superfamily Protein Y37A1A.2 {ECO:0000313|EMBL:CAB16469.4} OS=Caenorhabditis elegans PE=4 SV=4 R General function prediction only Protein Y37A1A.2 [Caenorhabditis elegans] Y69A2AR.19 gene13767 358 449 487 196 232 202 5.110466 6.594181886 7.0372213 2.906375507 3.3618078952 2.9867653440539 1.49752157350696e-05 -1.05239098455785 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- -- -- Protein-tyrosine phosphatase;; Domain of unknown function;; Dual specificity phosphatase, catalytic domain Protein Y69A2AR.19, isoform a {ECO:0000313|EMBL:CCD74137.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein Y69A2AR.19 [Caenorhabditis elegans] slc-25A10 gene42990 2063 2079 2162 6348 6115 7083 83.1185120045102 77.9920974783955 77.4498196410412 261.8012026 244.30903233 288.262166627 5.17387580747771e-20 1.61840256243018 up -- -- -- K13577|0|cel:CELE_K11G12.5|K11G12.5; Protein K11G12.5; K13577 solute carrier family 25 (mitochondrial dicarboxylate transporter), member 10 (A) -- [C] Energy production and conversion Mitochondrial carrier protein Protein K11G12.5 {ECO:0000313|EMBL:CCD70797.1} OS=Caenorhabditis elegans PE=2 SV=1 S Function unknown Protein K11G12.5 [Caenorhabditis elegans] spp-18 gene18994 1606 2011 1524 781 695 679 756.6100239639 864.81000904928 673.3700131126 370.33470959552 416.057322312 363.2553254506 1.18949853092751e-10 -1.26804951149728 down -- -- -- -- -- -- -- -- Protein SPP-18, isoform a {ECO:0000313|EMBL:CAA92462.1} OS=Caenorhabditis elegans PE=4 SV=1 V Defense mechanisms Protein SPP-18 [Caenorhabditis elegans] T05C3.6 gene34565 280 304 312 129 131 128 11.150910125 13.352546 15.216736887 6.724390279 5.44398796 5.572186804 2.79260341046324e-06 -1.22158235770095 down -- -- Molecular Function: catalytic activity (GO:0003824);; -- -- [R] General function prediction only PLD-like domain;; PLD-like domain;; Phospholipase D Active site motif Protein T05C3.6, isoform a {ECO:0000313|EMBL:CCD65542.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T05C3.6, isoform a [Caenorhabditis elegans] Y48E1B.8 gene8940 65 61 82 13 21 11 3.86001 3.752109 4.98728 0.86190890754 1.450829 0.5721231 5.71356755834137e-08 -2.22306784001206 down -- -- -- -- -- -- -- Nucleotide-diphospho-sugar transferase Protein Y48E1B.8 {ECO:0000313|EMBL:CAB07694.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein Y48E1B.8 [Caenorhabditis elegans] T07E3.2 gene11268 13 21 23 110 68 122 18.816703 30.809435 22.4802 29.41634 8.3312 40.10426 1.84118461735735e-06 2.38169557315322 up -- -- -- -- -- -- -- -- Protein T07E3.2 {ECO:0000313|EMBL:CCD72021.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T07E3.2 [Caenorhabditis elegans] ztf-14 gene45735 147 135 85 255 455 441 3.69700843291486 3.637768494026 2.35041509506 6.2265386 10.920445 10.4038699552 0.000674206017342223 1.63655524767394 up [R] General function prediction only -- -- -- [R] General function prediction only Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger Protein ZTF-14 {ECO:0000313|EMBL:CAB01893.4} OS=Caenorhabditis elegans PE=4 SV=4 S Function unknown Protein ZTF-14 [Caenorhabditis elegans] C31C9.2 gene8957 4621 4417 3694 21661 20127 25456 297.8163 273.2373 234.2564 1310.062 1243.864 1517.327 2.35986539683864e-35 2.38720313469854 up [HE] Coenzyme transport and metabolism;; Amino acid transport and metabolism Molecular Function: phosphogluconate dehydrogenase (decarboxylating) activity (GO:0004616);; Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; K00058|0|cel:CELE_C31C9.2|C31C9.2; Protein C31C9.2; K00058 D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] (A) Glycine, serine and threonine metabolism (ko00260);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain;; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain;; NAD binding domain of 6-phosphogluconate dehydrogenase;; Acetohydroxy acid isomeroreductase, catalytic domain Protein C31C9.2 {ECO:0000313|EMBL:CAB05694.1} OS=Caenorhabditis elegans PE=1 SV=1 R General function prediction only Protein C31C9.2 [Caenorhabditis elegans] ugt-27 gene1006 67 54 19 100 107 90 2.554561 2.115819 0.663703 3.45211 4.417717 3.66862 0.00559352088396428 1.07201539238881 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-27 {ECO:0000313|EMBL:CCD64217.1} OS=Caenorhabditis elegans PE=3 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein UGT-27 [Caenorhabditis elegans] B0462.4 gene39915 242 305 235 1166 956 1156 108.017261644 125.865027902 96.997397701 513.982210145 509.106100106 588.040354707 4.65755758278472e-24 2.05395022440794 up -- -- -- -- -- -- -- -- Protein B0462.4 {ECO:0000313|EMBL:CAE17676.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein B0462.4 [Caenorhabditis elegans] ttr-37 gene41026 91 133 60 286 235 347 13.518629621 20.28276 9.15178 55.1778 44.31405 67.4509 3.41161747003357e-06 1.59955867364921 up -- -- Cellular Component: extracellular space (GO:0005615);; -- -- -- -- Transthyretin-like family Protein TTR-37 {ECO:0000313|EMBL:CCD69803.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein TTR-37 [Caenorhabditis elegans] C17H12.6 gene17819 530 628 369 145 93 102 39.22663 43.43419 24.45416 10.073999 8.78755 6.9698364039 1.75218587760812e-07 -2.1809452003652 down -- -- -- -- -- -- -- CUB-like domain Protein C17H12.6, isoform a {ECO:0000313|EMBL:CDK13470.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only C17H12.6, isoform a [Caenorhabditis elegans] clec-73 gene14170 435 528 368 203 192 205 13.5315 16.197 11.288 6.23156 5.9347 6.30612 1.12987019560867e-06 -1.16281580172714 down -- -- -- -- -- -- -- Lectin C-type domain Protein CLEC-73 {ECO:0000313|EMBL:CCD71963.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-73 [Caenorhabditis elegans] C45G9.4 gene10717 75 97 120 40 49 53 4.500146 5.562980114547 6.960415 2.3605851 2.706520145227 3.0075700333015 0.00420893874684713 -1.05403014363654 down -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EGT45575.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein C45G9.4 [Caenorhabditis elegans] C23G10.6 gene11049 243 256 90 877 789 1054 9.087540511912 9.39798 3.386085 30.932701 28.544388 39.419727 5.65873192161271e-15 2.19490236201483 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein C23G10.6 {ECO:0000313|EMBL:CCD65307.1} OS=Caenorhabditis elegans PE=3 SV=2 J Translation, ribosomal structure and biogenesis Protein C23G10.6 [Caenorhabditis elegans] col-181 gene44921 12713 13221 21899 4890 4105 4668 766.543 764.27 1314.369 288.4351 250.4637 291.559 0.000624610879406275 -1.82309649247909 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-181, isoform a {ECO:0000313|EMBL:CAA91544.2} OS=Caenorhabditis elegans PE=4 SV=2 DKT Cell cycle control, cell division, chromosome partitioning;; Transcription;; Signal transduction mechanisms Protein COL-181, isoform a [Caenorhabditis elegans] catp-3 gene35583 1542 1652 1264 4091 4613 5581 25.87769 27.8007096 21.0091612 69.777908 79.136545121 101.55762 1.57629076568886e-12 1.6668729066385 up -- -- -- -- -- [P] Inorganic ion transport and metabolism E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase Protein CATP-3, isoform a {ECO:0000313|EMBL:CCD64050.1} OS=Caenorhabditis elegans PE=3 SV=2 T Signal transduction mechanisms Protein CATP-3, isoform a [Caenorhabditis elegans] srh-2 gene33106 14 9 20 115 104 85 0.663621717090401 0.71636616001623 0.861809887100001 5.67324970871015 7.73192549200137 6.285616175634 9.87351804773552e-14 2.80533957047288 up -- -- -- -- -- -- -- Serpentine type 7TM GPCR chemoreceptor Srh Protein SRH-2, isoform c {ECO:0000313|EMBL:CCD63244.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein SRH-2, isoform c [Caenorhabditis elegans] kin-24 gene19089 62 45 76 24 20 13 2.30532 1.709 2.88968 0.923938 0.774486 0.538218 9.96228285244344e-05 -1.69898966853154 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain;; Kinase-like;; SH2 domain Protein KIN-24 {ECO:0000313|EMBL:CBL87056.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein KIN-24 [Caenorhabditis elegans] F10G2.2 gene35282 29 36 9 63 56 73 21.6127 23.229 6.28663 45.9651 57.1384 64.7601 0.00112944807565603 1.36374113324822 up -- -- -- -- -- -- -- -- Protein F10G2.2 {ECO:0000313|EMBL:CCD62810.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein F10G2.2 [Caenorhabditis elegans] pudl-1 gene13859 59 34 45 21 8 19 15.4611 8.18187 11.2689 5.39125 2.593 5.39384 0.00234737683046638 -1.53944544144955 down -- -- -- -- -- -- -- -- Protein PUDL-1 {ECO:0000313|EMBL:CCD83531.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein PUDL-1 [Caenorhabditis elegans] srd-33 gene34361 18 11 5 28 39 42 1.63419 0.959687 0.48125 2.49877 3.67475 3.8457 0.00109147075616867 1.66774778144286 up -- -- -- K08473|0|cel:CELE_T19H12.4|srd-33; Protein SRD-33; K08473 nematode chemoreceptor (A) -- -- -- Serpentine type 7TM GPCR chemoreceptor Srd;; Serpentine type 7TM GPCR chemoreceptor Str;; Serpentine type 7TM GPCR chemoreceptor Srj;; Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Sri CRE-SRD-33 protein {ECO:0000313|EMBL:EFO99739.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein SRD-33 [Caenorhabditis elegans] M05D6.8 gene7302 478 348 548 1153 1659 1682 7.43855 6.75583 8.79658 14.80792 21.77368 23.805364 7.58449240902321e-08 1.69508126011834 up -- -- -- -- -- -- -- ShK domain-like Protein M05D6.8, isoform b {ECO:0000313|EMBL:CBX53331.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein M05D6.8, isoform b [Caenorhabditis elegans] pcp-4 gene40416 2247 2199 1376 835 858 704 33.560386501591 31.62191000001 19.7616400396103 11.8070500000224 12.362381 9.81878800000007 0.000404242076026254 -1.29382164115335 down -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; -- -- [OR] Posttranslational modification, protein turnover, chaperones;; General function prediction only Serine carboxypeptidase S28;; Alpha/beta hydrolase family Protein PCP-4 {ECO:0000313|EMBL:CAC14390.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein PCP-4 [Caenorhabditis elegans] F42G4.2 gene8848 98 110 134 36 50 63 3.75870410869707 4.17911147 5.2311862806 1.44103033232044 2.12161187 2.7740753614 0.000443470187748521 -1.21230675154273 down -- -- -- -- -- -- -- -- Protein F42G4.2 {ECO:0000313|EMBL:CAB03093.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F42G4.2 [Caenorhabditis elegans] lec-7 gene44147 55 71 39 125 92 117 9.40908 11.2606 6.37322 20.6382 17.0275 20.5052 0.00473608694800598 1.0042327271808 up -- -- Molecular Function: carbohydrate binding (GO:0030246);; -- -- [W] Extracellular structures Galactoside-binding lectin Galectin {ECO:0000256|RuleBase:RU102079} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein LEC-7 [Caenorhabditis elegans] F57G4.11 gene39675 6 10 0 47 45 61 0.2638667 0.443975 0.04009041 2.095556 2.073163 2.9749 6.34616323462656e-11 3.24767663092044 up -- -- -- -- -- -- -- FTH domain Protein F57G4.11 {ECO:0000313|EMBL:CBO24680.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F57G4.11 [Caenorhabditis elegans] F09C6.3 gene39354 31 38 25 92 84 70 3.68735 4.20048 2.78924 10.5191 10.2278 8.54554 0.000350199205763304 1.37435088400147 up -- -- -- -- -- -- -- -- Protein F09C6.3 {ECO:0000313|EMBL:CCO25915.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein F09C6.3 [Caenorhabditis elegans] prmt-4 gene13352 20 16 5 45 48 43 2.055208 2.286855 1.140083 4.80964 5.39004 4.99127 0.00026669555103533 1.71704285288608 up [QR] Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: S-adenosylmethionine-dependent methyltransferase activity (GO:0008757);; Biological Process: oligosaccharide biosynthetic process (GO:0009312);; Biological Process: nodulation (GO:0009877);; -- -- -- -- Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Nodulation protein S (NodS);; Protein of unknown function (DUF1698);; Tellurite resistance protein TehB;; Ribosomal protein L11 methyltransferase (PrmA);; Methyltransferase small domain;; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Protein PRMT-4 {ECO:0000313|EMBL:CCD63294.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein PRMT-4 [Caenorhabditis elegans] K09E4.1 gene9114 91 98 80 40 43 39 6.23258 6.78016 5.61632 2.754975 3.100014 2.774228 0.0020933758837976 -1.15440590866821 down -- -- -- -- -- [T] Signal transduction mechanisms -- Protein K09E4.1 {ECO:0000313|EMBL:CAB70168.1} OS=Caenorhabditis elegans PE=1 SV=1 R General function prediction only Protein K09E4.1 [Caenorhabditis elegans] cyp-29A3 gene32908 330 330 237 128 127 114 12.4877 12.3552 8.86583 4.91276 4.92533 4.48645 5.90000818473413e-07 -1.29519252695178 down -- -- Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17952|0|cel:CELE_Y38C9B.1|cyp-29A3; Protein CYP-29A3; K17952 cytochrome P450, family 29, subfamily A (A) -- [QI] Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism Cytochrome P450 Protein CYP-29A3 {ECO:0000313|EMBL:CCD61789.1} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein CYP-29A3 [Caenorhabditis elegans] F58G6.9 gene19016 89 95 76 219 131 181 21.81538 19.70725919 21.776719 47.98374 40.01597 53.36279 0.00439822925580469 1.0158516740295 up -- -- Molecular Function: copper ion transmembrane transporter activity (GO:0005375);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: copper ion transmembrane transport (GO:0035434);; -- -- [P] Inorganic ion transport and metabolism Ctr copper transporter family Protein F58G6.9, isoform a {ECO:0000313|EMBL:CAI59117.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein F58G6.9, isoform a [Caenorhabditis elegans] oac-31 gene33294 623 847 753 2475 2237 1998 18.17055840556 26.433302378 22.81839 78.040528 72.659766 64.735447 8.94406474586163e-18 1.57980328267207 up -- -- Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [R] General function prediction only Acyltransferase family Protein OAC-31 {ECO:0000313|EMBL:CCD69592.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein OAC-31 [Caenorhabditis elegans] C09B9.7 gene14919 87 80 94 26 51 51 1.4917106 1.407728 1.655897 0.4692117498 0.929331 1.015349 0.00647160171929197 -1.04128316713036 down -- -- -- -- -- -- -- Domain of unknown function Protein C09B9.7 {ECO:0000313|EMBL:CCD63831.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms C09B9.7 [Caenorhabditis elegans] acs-6 gene6802 120 106 142 51 59 74 4.048315974 3.7456472122 4.601286626 1.746225 1.9721772795916 3.0519415 0.00308901837113092 -1.0142768916844 down [IQ] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; K01904|0|cel:CELE_ZK1127.2|acs-6; Protein ACS-6; K01904 4-coumarate--CoA ligase [EC:6.2.1.12] (A) Ubiquinone and other terpenoid-quinone biosynthesis (ko00130);; Phenylalanine metabolism (ko00360) [I] Lipid transport and metabolism AMP-binding enzyme;; AMP-binding enzyme C-terminal domain Protein ACS-6 {ECO:0000313|EMBL:CCD73714.1} OS=Caenorhabditis elegans PE=4 SV=1 L Replication, recombination and repair Protein ACS-6 [Caenorhabditis elegans] elo-5 gene15431 1356 1544 1433 4774 3927 4024 133.9558 149.5021 141.8022 464.718 412.319 386.77576594 5.11862755460744e-18 1.53995259408143 up -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [I] Lipid transport and metabolism GNS1/SUR4 family Elongation of very long chain fatty acids protein {ECO:0000256|RuleBase:RU361115} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown ELO-5, isoform b [Caenorhabditis elegans] mltn-3 gene9034 60 75 66 29 31 24 1.3042822399 1.633043679112 1.44302263157 0.6433840951 0.663617223 0.527883619 0.00198391117120823 -1.27259689798205 down -- -- -- -- -- -- -- Moulting cycle Protein MLTN-3 {ECO:0000313|EMBL:CAB03459.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein MLTN-3 [Caenorhabditis elegans] cyp-13A6 gene7787 1007 1480 1162 2928 2668 2373 37.680178 55.85820155162 43.76290210866 114.514199 106.56510179063 100.31830122438 2.46460472164291e-09 1.11323411041811 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17861|0|cel:CELE_T10B9.3|cyp-13A6; Protein CYP-13A6; K17861 cytochrome P450, family 13 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 CRE-CYP-13A6 protein {ECO:0000313|EMBL:EFP13149.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-13A6 [Caenorhabditis elegans] pck-3 gene16520 115 175 152 54 73 53 3.4705477 5.179822115 4.5053016 1.57244033 2.2465887535 1.598200404 3.4309249812907e-05 -1.30933154623384 down [C] Energy production and conversion Molecular Function: phosphoenolpyruvate carboxykinase activity (GO:0004611);; Biological Process: gluconeogenesis (GO:0006094);; -- -- [C] Energy production and conversion Phosphoenolpyruvate carboxykinase Protein PCK-3 {ECO:0000313|EMBL:CCD63377.1} OS=Caenorhabditis elegans PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein PCK-3 [Caenorhabditis elegans] Y11D7A.5 gene18849 176 151 121 67 51 56 52.2688 40.7536 33.1328 19.969 17.6988 18.8761 1.12797649209554e-05 -1.3787738122226 down -- -- -- -- -- -- -- -- Protein Y11D7A.5 {ECO:0000313|EMBL:CAA21590.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y11D7A.5 [Caenorhabditis elegans] F45D11.14 gene4522 528 651 422 119 96 154 20.5732 25.8339 16.8049 4.86187 3.9414 6.65127 3.6708594517891e-10 -2.13027542416839 down -- -- -- -- -- -- -- Protein of unknown function (DUF684) Protein F45D11.14 {ECO:0000313|EMBL:CCD66368.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F45D11.14 [Caenorhabditis elegans] C27H5.6 gene6843 16 8 13 45 36 49 1.40881298 0.708818 1.10666 3.946517 3.4441277 6.6628 0.000171174524897217 1.79738485831056 up -- -- -- -- -- -- -- -- Protein C27H5.6 {ECO:0000313|EMBL:CCD65893.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C27H5.6 [Caenorhabditis elegans] fmo-1 gene19434 565 587 381 1702 1647 1948 20.64483 21.2291 13.77126 64.8629 62.9389 77.6748 5.63355357449458e-21 1.77558793686728 up [P] Inorganic ion transport and metabolism Molecular Function: N,N-dimethylaniline monooxygenase activity (GO:0004499);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; K00485|0|cel:CELE_K08C7.2|fmo-1; Protein FMO-1; K00485 dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] (A) Drug metabolism - cytochrome P450 (ko00982) [Q] Secondary metabolites biosynthesis, transport and catabolism Flavin-binding monooxygenase-like;; Pyridine nucleotide-disulphide oxidoreductase;; L-lysine 6-monooxygenase (NADPH-requiring);; Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; NAD(P)-binding Rossmann-like domain Dimethylaniline monooxygenase [N-oxide-forming] {ECO:0000256|PIRNR:PIRNR000332} OS=Caenorhabditis elegans PE=2 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein FMO-1 [Caenorhabditis elegans] fat-1 gene20437 7461 7096 7624 21107 20731 22576 437.203608 412.19694 438.41675 1206.13282 1171.08267 1253.63668 1.79648856368764e-16 1.52377675044673 up [I] Lipid transport and metabolism Biological Process: lipid metabolic process (GO:0006629);; K10257|0|cel:CELE_Y67H2A.8|fat-1; Protein FAT-1; K10257 omega-3 fatty acid desaturase (delta-15 desaturase) [EC:1.14.19.-] (A) Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212) -- -- Fatty acid desaturase Protein CBR-FAT-1 {ECO:0000313|EMBL:CAP22846.1} OS=Caenorhabditis briggsae PE=4 SV=1 R General function prediction only Protein FAT-1 [Caenorhabditis elegans] ugt-31 gene411 1445 1861 1817 5923 5505 5686 58.5043 76.25256 73.91344 247.1805 242.5918 259.5412 1.44920258988698e-22 1.72609634839324 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-31 {ECO:0000313|EMBL:CCD69904.1} OS=Caenorhabditis elegans PE=4 SV=1 Z Cytoskeleton Protein UGT-31 [Caenorhabditis elegans] Y62E10A.13 gene20464 4387 4267 2779 15163 13668 15535 310.429947217485 295.795581647924 194.476774499724 1042.80723629142 966.736598076014 1084.81625369282 6.86142113961985e-27 1.94274795657878 up [E] Amino acid transport and metabolism -- K01079|7.54646e-154|cbr:CBG01775|Hypothetical protein CBG01775; K01079 phosphoserine phosphatase [EC:3.1.3.3] (A) Glycine, serine and threonine metabolism (ko00260);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase Protein Y62E10A.13, isoform f {ECO:0000313|EMBL:CDR32651.1} OS=Caenorhabditis elegans PE=4 SV=1 A RNA processing and modification Y62E10A.13, isoform f [Caenorhabditis elegans] F59D6.1 gene33782 24 29 29 52 65 71 4.17129414605 26.268429 40.02905146544 136.714677 29.8377878 102.888715 0.00535621266303305 1.18354318906854 up -- -- -- -- -- -- -- -- Protein F59D6.1 {ECO:0000313|EMBL:CCD67828.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F59D6.1 [Caenorhabditis elegans] dhs-30 gene46611 529 545 587 1363 1274 1766 33.30677 32.73032 35.3067 82.7654 78.5657 112.4827 2.5195539605086e-08 1.39241310984836 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only Molecular Function: methylenetetrahydrofolate dehydrogenase (NADP+) activity (GO:0004488);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain;; NADH(P)-binding;; Fungal family of unknown function (DUF1776);; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Protein DHS-30 {ECO:0000313|EMBL:CCD74455.1} OS=Caenorhabditis elegans PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein DHS-30 [Caenorhabditis elegans] col-81 gene8171 4674 7081 6920 2206 2176 2062 244.80689 354.90962 347.88856 109.85778 108.23282 101.99791 5.54812801158478e-07 -1.54896101140172 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-81 {ECO:0000313|EMBL:CAA90187.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-81 [Caenorhabditis elegans] F46F5.11 gene4446 35 29 30 6 6 9 0.8636843986 0.781221696 0.774226 0.164169693 0.169985402 0.264046057 6.43593530082364e-05 -2.17616591217613 down -- -- -- -- -- -- -- Protein of unknown function, DUF288 Protein F46F5.11 {ECO:0000313|EMBL:CCD70109.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F46F5.11 [Caenorhabditis elegans] Y39B6A.1 gene40194 9098 7423 6393 1089 1302 1021 144.8981166 107.54600211 94.012981159714 15.1206363798015 15.7724856346006 12.0317353000003 8.79932616250264e-21 -2.76153309834402 down -- -- -- -- -- -- -- -- Protein Y39B6A.1 {ECO:0000313|EMBL:CAC51077.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein Y39B6A.1 [Caenorhabditis elegans] irg-5 gene38005 3903 7768 3838 1307 1169 963 249.401 492.673 243.83 84.4347 74.8722 63.8148 0.00467753101982954 -2.18558974460618 down -- -- -- -- -- -- -- CUB-like domain Protein F35E12.5 {ECO:0000313|EMBL:CAB04272.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F35E12.5 [Caenorhabditis elegans] lite-1 gene42805 311 323 196 536 591 571 18.366702831 18.5021787103 11.219913539 31.4037973899 36.9866977696 35.492220014 1.06448780243989e-05 1.0195504866954 up -- -- Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; -- -- -- -- 7tm Chemosensory receptor CRE-LITE-1 protein {ECO:0000313|EMBL:EFO82714.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only Protein LITE-1 [Caenorhabditis elegans] gst-12 gene8950 1203 1157 1222 683 490 561 198.5049 181.8309 197.1289 112.5966 82.6239 90.972 1.60679578038391e-07 -1.06147504043954 down [O] Posttranslational modification, protein turnover, chaperones Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein GST-12 {ECO:0000313|EMBL:CAB02288.1} OS=Caenorhabditis elegans PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein GST-12 [Caenorhabditis elegans] fbxa-7 gene9936 8 8 4 27 26 31 0.63433952902 0.643809 0.358606190651 2.144841 2.13195 2.57596 0.000308904196155631 2.05749749706887 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-7 {ECO:0000313|EMBL:CCD67061.1} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein FBXA-7 [Caenorhabditis elegans] W02B12.1 gene8334 258 278 229 127 91 114 15.60463 17.10247 13.94612 8.04648 5.87408 7.806825 7.06068201427998e-06 -1.21841439271234 down -- -- Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; -- -- [I] Lipid transport and metabolism GDSL-like Lipase/Acylhydrolase Protein W02B12.1 {ECO:0000313|EMBL:CAA91393.2} OS=Caenorhabditis elegans PE=4 SV=2 I Lipid transport and metabolism Protein W02B12.1 [Caenorhabditis elegans] spe-46 gene2336 69 109 109 50 37 46 7.23315 11.2806 11.3381 5.35483 4.0822 5.1351 0.00227915891155902 -1.12379044523997 down -- -- -- -- -- -- -- -- Protein SPE-46 {ECO:0000313|EMBL:CAA22250.2} OS=Caenorhabditis elegans PE=4 SV=2 L Replication, recombination and repair Protein W06D4.2 [Caenorhabditis elegans] fbxa-188 gene39569 63 76 56 169 126 166 3.04679 3.5851707 2.62407 8.29952 6.25359 8.5505 9.51340695451466e-05 1.22762198615791 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-188 {ECO:0000313|EMBL:CAB07207.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein FBXA-188 [Caenorhabditis elegans] H18N23.2 gene46705 1768 1548 1300 3027 3500 3357 41.3963018050432 33.1131279 28.4640535611187 65.3025860000035 77.9379496 69.678882 4.09837436968699e-09 1.08471410960503 up -- -- Molecular Function: protein binding (GO:0005515);; Molecular Function: starch binding (GO:2001070);; -- -- [OT] Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms Putative phosphatase regulatory subunit Protein phosphatase 1 regulatory subunit 3 {ECO:0000256|PIRNR:PIRNR038207} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein H18N23.2, isoform b [Caenorhabditis elegans] F53C3.8 gene5609 17 16 9 38 41 35 0.5928624555 1.0357293 0.79058556335 1.3827932537 1.625513133 1.425798 0.00458823393957076 1.42727952734353 up -- -- -- -- -- -- -- -- Protein F53C3.8 {ECO:0000313|EMBL:CCD67678.1} OS=Caenorhabditis elegans PE=4 SV=2 Q Secondary metabolites biosynthesis, transport and catabolism Protein F53C3.8 [Caenorhabditis elegans] T06C10.3 gene18366 98 126 129 46 41 44 3.60139 4.78837 4.86208 1.77163 1.62366 1.84466 1.94590802336925e-05 -1.44426252442657 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain;; SH2 domain Protein T06C10.3 {ECO:0000313|EMBL:CCD63310.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T06C10.3 [Caenorhabditis elegans] col-133 gene22039 4636 4543 4680 1445 1343 1120 276.026 256.168 266.656 79.4409 73.5097 60.0813 3.01133991339538e-25 -1.84090012639422 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Nematode cuticle collagen N-terminal domain;; Collagen triple helix repeat (20 copies) Protein COL-133 {ECO:0000313|EMBL:CAB05195.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein COL-133 [Caenorhabditis elegans] Y47G6A.15 gene687 2041 2482 2668 826 877 847 141.9521 171.6462 186.133 58.1939 62.07397 61.59908 2.85360993950475e-16 -1.50977275035105 down -- -- -- -- -- -- -- -- Protein Y47G6A.15 {ECO:0000313|EMBL:CCD72560.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y47G6A.15 [Caenorhabditis elegans] fbxa-155 gene12328 39 49 56 13 18 16 2.208184 2.738272 3.188808 0.789267423501 1.062889 0.996418 0.000383012239747078 -1.62911688456004 down -- -- -- -- -- -- -- FTH domain Protein FBXA-220 {ECO:0000313|EMBL:CAC35865.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein FBXA-155 [Caenorhabditis elegans] F27D9.2 gene43382 185 211 144 403 378 456 8.931907 10.422094 6.661615 19.3717 19.54287 24.049617 1.16215123609124e-06 1.1825718340475 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [R] General function prediction only Major Facilitator Superfamily Protein F27D9.2 {ECO:0000313|EMBL:CCD67917.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein F27D9.2 [Caenorhabditis elegans] sulp-8 gene36184 464 508 326 1844 2041 2064 16.104031848 18.1251 10.7119809952 62.895069297 72.97805522 74.25956186 4.79982419154909e-31 2.18328621640203 up [P] Inorganic ion transport and metabolism Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; K14453|0|cel:CELE_ZK287.2|sulp-8; Protein SULP-8, isoform A; K14453 solute carrier family 26, other (A) -- [P] Inorganic ion transport and metabolism Sulfate transporter family;; Sulfate transporter N-terminal domain with GLY motif;; STAS domain Protein SULP-8, isoform a {ECO:0000313|EMBL:CAA94798.1} OS=Caenorhabditis elegans PE=2 SV=1 R General function prediction only Protein SULP-8, isoform a [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_570 94 108 52 20 29 9 3.35782 3.83264 1.82791 0.738167 1.09712 0.355442 0.00069740011824598 -2.14372255910709 down -- -- -- -- -- [R] General function prediction only -- Protein F08F3.10 {ECO:0000313|EMBL:CCD65601.1} OS=Caenorhabditis elegans PE=4 SV=2 Q Secondary metabolites biosynthesis, transport and catabolism -- clec-72 gene14168 3182 3401 1436 6780 6809 7334 143.882 148.655 62.6459 303.237 306.527 331.812 3.06547615638871e-10 1.37098924241502 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-72 {ECO:0000313|EMBL:CCD71967.1} OS=Caenorhabditis elegans PE=4 SV=3 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-72 [Caenorhabditis elegans] cpb-2 gene6426 92 128 125 45 44 69 3.58081 5.07848 4.91074 1.82151 1.84243 3.0885 0.000974822698949298 -1.14002856331734 down -- -- Molecular Function: nucleic acid binding (GO:0003676);; K02602|0|cel:CELE_C30B5.3|cpb-2; Protein CPB-2; K02602 cytoplasmic polyadenylation element-binding protein (A) Dorso-ventral axis formation (ko04320) [J] Translation, ribosomal structure and biogenesis RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CRE-CPB-2 protein {ECO:0000313|EMBL:EFP07545.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein CPB-2 [Caenorhabditis elegans] C14C6.8 gene33034 105 104 99 60 37 54 4.475936 4.411867 4.264678 2.64076229654 1.71896085861 2.424452 0.00399936759747246 -1.04297670489642 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein C14C6.8 {ECO:0000313|EMBL:CCD64464.2} OS=Caenorhabditis elegans PE=4 SV=3 K Transcription C14C6.8 [Caenorhabditis elegans] cysl-2 gene9193 6024 5699 6162 15583 14232 15996 281.0349 267.905 298.298 733.986 672.369 758.373 1.83218984360704e-13 1.34254835783266 up [E] Amino acid transport and metabolism -- K01738|0|cel:CELE_K10H10.2|cysl-2; Protein CYSL-2; K01738 cysteine synthase A [EC:2.5.1.47] (A) Cysteine and methionine metabolism (ko00270);; Sulfur metabolism (ko00920);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Pyridoxal-phosphate dependent enzyme Cysteine synthase {ECO:0000256|RuleBase:RU003985} OS=Caenorhabditis elegans PE=1 SV=1 R General function prediction only Protein CYSL-2 [Caenorhabditis elegans] C36C5.5 gene33824 336 323 224 136 75 138 49.9492 45.5959 32.2337 19.6998 12.3139 21.0634 8.31661146896254e-05 -1.35316764142776 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein C36C5.5 {ECO:0000313|EMBL:CCD66859.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C36C5.5 [Caenorhabditis elegans] col-80 gene8086 11324 13244 15795 6195 6050 6496 516.187 555.178 665.146 257.5055 241.0466 256.6612 4.17127098354925e-07 -1.12120274209015 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein CBR-COL-80 {ECO:0000313|EMBL:CAP23598.1} OS=Caenorhabditis briggsae PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein COL-80 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_477 10 5 13 40 32 34 0.677031 0.3305507 0.866826 2.512436 2.1081426793 2.345049 0.000234255782157734 1.90396257137219 up -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease;; Eukaryotic aspartyl protease Putative uncharacterized protein {ECO:0000313|EMBL:EGT60508.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones PREDICTED: lysosomal aspartic protease-like isoform X1 [Musca domestica] mam-7 gene12276 32 37 39 11 12 15 1.31317864088 1.4838141831 1.550138434 0.46565009139 0.5352701299 0.721182 0.00286292252355507 -1.52068907306991 down -- -- Cellular Component: membrane (GO:0016020);; -- -- -- -- MAM domain Protein MAM-7 {ECO:0000313|EMBL:CAA82936.2} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein MAM-7 [Caenorhabditis elegans] K06H6.4 gene33043 29 37 37 12 13 8 1.18425 1.4672 1.46668 0.489767 0.566098 0.342046 0.00140478269461361 -1.65640809040294 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein K06H6.4 {ECO:0000313|EMBL:CCD64477.2} OS=Caenorhabditis elegans PE=4 SV=3 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein K06H6.4 [Caenorhabditis elegans] Y116A8C.38 gene32469 22 40 39 16 11 12 0.900588 1.61623 1.59204 0.671232 0.47792 0.545596 0.00819797862205267 -1.38714546191209 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain;; SH2 domain Protein Y116A8C.38, isoform a {ECO:0000313|EMBL:CAB55139.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein Y116A8C.38, isoform a [Caenorhabditis elegans] K06H6.1 gene33049 270 237 254 94 82 52 15.4932 13.2193 14.2679 5.28829 4.76521 3.03026 8.34344095319397e-11 -1.75401140153915 down -- -- -- -- -- -- -- Caenorhabditis protein of unknown function, DUF268 Protein K06H6.1 {ECO:0000313|EMBL:CCD64472.1} OS=Caenorhabditis elegans PE=4 SV=1 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein K06H6.1 [Caenorhabditis elegans] F58H1.6 gene37266 80 81 75 43 43 28 6.6023 6.13109 5.71484 3.56143 3.58469 2.49429 0.00709039167511974 -1.06420237097628 down -- -- -- -- -- -- -- -- Protein F58H1.6 {ECO:0000313|EMBL:CAB00109.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F58H1.6 [Caenorhabditis elegans] F09C8.1 gene46312 1693 1963 1277 529 590 602 87.219 98.1843 64.98353 25.80997 27.6901 29.20583 2.2431634378446e-07 -1.53221983556763 down -- -- Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; -- -- [I] Lipid transport and metabolism GDSL-like Lipase/Acylhydrolase;; GDSL-like Lipase/Acylhydrolase family Protein F09C8.1 {ECO:0000313|EMBL:CAA92221.2} OS=Caenorhabditis elegans PE=4 SV=2 I Lipid transport and metabolism Protein F09C8.1 [Caenorhabditis elegans] F07E5.9 gene4915 38 26 22 82 113 117 1.412931 0.834168 0.665882 2.582559 3.517964 3.797336477 1.81544572901292e-07 1.84552928751117 up -- -- -- -- -- -- -- -- Protein F07E5.9 {ECO:0000313|EMBL:CCD61279.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F07E5.9 [Caenorhabditis elegans] gska-3 gene2230 98 154 172 61 39 69 5.39769 8.38323 9.3355 3.38217 2.18051 4.00487 0.00266665898039524 -1.34128668930918 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [G] Carbohydrate transport and metabolism Protein kinase domain;; Protein tyrosine kinase Protein GSKA-3 {ECO:0000313|EMBL:CAB02275.1} OS=Caenorhabditis elegans PE=4 SV=1 Z Cytoskeleton Protein GSKA-3 [Caenorhabditis elegans] cest-1 gene38172 372 343 346 983 1062 1112 11.93047 11.08015 11.12529 32.49288 36.25893 38.7834 1.37395577224385e-14 1.55908798046094 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein T02B5.1 {ECO:0000313|EMBL:CAB03272.2} OS=Caenorhabditis elegans PE=3 SV=2 T Signal transduction mechanisms Protein T02B5.1 [Caenorhabditis elegans] W03F11.5 gene381 57 39 55 157 127 168 3.4932084114 2.23535500615 3.92897892 9.2181980913 7.784597768 9.81233 5.54812801158478e-07 1.56663403609239 up -- -- -- -- -- -- -- -- Protein W03F11.5 {ECO:0000313|EMBL:CCD69312.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein W03F11.5 [Caenorhabditis elegans] fipr-3 gene45703 39 46 41 32 7 12 55.1173 57.4822 54.5643 46.5341 16.0921 22.0261 0.00905051487670173 -1.32121880028444 down -- -- -- -- -- -- -- -- Protein FIPR-3 {ECO:0000313|EMBL:CAD56578.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein FIPR-3 [Caenorhabditis elegans] F32B6.4 gene19111 58 69 82 27 29 25 7.21678 8.44236 10.1438 3.38496 3.82125 3.36296 0.000627510762897745 -1.38191393636062 down -- -- -- -- -- -- -- -- Protein F32B6.4 {ECO:0000313|EMBL:CAB03040.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F32B6.4 [Caenorhabditis elegans] C06G3.3 gene17995 9 17 3 102 75 125 368.268 816.063 173.16 5186.4 6270.68 9181.49 2.06818139131618e-11 3.36972089124384 up -- -- -- -- -- -- -- -- Protein C06G3.3 {ECO:0000313|EMBL:CCD83550.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C06G3.3 [Caenorhabditis elegans] cpt-4 gene34420 687 460 701 173 198 193 18.93548 12.58357 17.554291 4.674184 5.547174 5.464387 2.69915104196906e-07 -1.72716816595696 down -- -- Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; -- -- [I] Lipid transport and metabolism Choline/Carnitine o-acyltransferase Protein CPT-4 {ECO:0000313|EMBL:CCD64399.1} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein CPT-4 [Caenorhabditis elegans] H20E11.3 gene17821 389 527 295 151 161 126 27.15461 37.00668 20.0986 10.91167 12.10263 9.85226 0.000701917245834245 -1.48012138564272 down -- -- -- -- -- -- -- CUB-like domain Protein H20E11.3, isoform b {ECO:0000313|EMBL:CCD63086.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein H20E11.3, isoform b [Caenorhabditis elegans] F22F7.7 gene33467 450 361 441 1656 1899 1953 34.3768677151 24.464065893664 32.217977425 115.036247164 132.154226091 125.905874748 4.63203755614201e-29 2.12289025471446 up [P] Inorganic ion transport and metabolism Molecular Function: gamma-glutamylcyclotransferase activity (GO:0003839);; Biological Process: glutathione catabolic process (GO:0006751);; K07232|1.33549e-154|cel:CELE_F22F7.7|F22F7.7; Protein F22F7.7; K07232 cation transport protein ChaC (A) -- [P] Inorganic ion transport and metabolism ChaC-like protein Protein F22F7.7 {ECO:0000313|EMBL:CCD67446.1} OS=Caenorhabditis elegans PE=4 SV=2 G Carbohydrate transport and metabolism Protein F22F7.7 [Caenorhabditis elegans] M70.3 gene13708 165 197 194 67 115 93 3.685164 4.455450866 4.314634 1.55462267 2.758199522 2.3696021362 0.000628439310443799 -1.02888026821987 down -- -- -- -- -- -- -- Domain of unknown function Protein M70.3, isoform a {ECO:0000313|EMBL:CCD66975.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein M70.3, isoform a [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_547 21 29 27 12 6 3 0.949101 1.26911 1.16065 0.525554 0.272614 0.134166 0.00120245063543871 -1.89039771801038 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92;; Glycosyltransferase family 92 Protein C14C6.7 {ECO:0000313|EMBL:CCD64463.1} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription -- K07E3.9 gene43522 31 41 57 14 13 21 3.93142 5.15582 6.99869 1.8035 1.80204 2.83563 0.00549678440275514 -1.44049885747931 down -- -- -- -- -- -- -- -- Protein K07E3.9 {ECO:0000313|EMBL:CCD62522.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein K07E3.9 [Caenorhabditis elegans] fbxa-164 gene4728 30 37 13 85 51 62 2.29682 2.8448 0.993182 6.62105 4.14027 5.14538 0.00928511334963959 1.29436325118777 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-164 {ECO:0000313|EMBL:CCD63671.1} OS=Caenorhabditis elegans PE=1 SV=1 R General function prediction only Protein FBXA-164 [Caenorhabditis elegans] ZK418.2 gene11326 73 97 101 42 41 38 4.269152 5.85107 6.160909 2.660494 2.708753 2.514005 0.00162682338977278 -1.17744431404066 down -- -- -- -- -- -- -- -- Protein ZK418.2, isoform a {ECO:0000313|EMBL:CCD61621.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZK418.2, isoform a [Caenorhabditis elegans] nhr-137 gene42958 226 188 166 413 421 500 10.8883226685917 9.11688130270558 8.527310470972 21.831950617918 23.7082551441032 28.9605133380686 6.88806373728112e-07 1.18776419814551 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- -- -- Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Protein NHR-137, isoform b {ECO:0000313|EMBL:CCD65643.1} OS=Caenorhabditis elegans PE=3 SV=2 K Transcription Protein NHR-137, isoform b [Caenorhabditis elegans] C35E7.10 gene2960 118 159 206 68 74 66 6.132255 9.038184 11.49553 3.314175 4.171078 3.5492100000041 0.00263721440714579 -1.22990327050601 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain;; SH2 domain Protein C35E7.10, isoform a {ECO:0000313|EMBL:CCD66816.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C35E7.10, isoform a [Caenorhabditis elegans] ZK54.3 gene46675 2867 2560 2340 4761 5403 6084 36.456400301 33.820496 30.510331973 61.91159932 68.990210937 79.736425947 9.01528284721036e-09 1.0511118657896 up -- -- -- -- -- [G] Carbohydrate transport and metabolism -- Protein ZK54.3 {ECO:0000313|EMBL:CCD66909.1} OS=Caenorhabditis elegans PE=4 SV=3 G Carbohydrate transport and metabolism Protein ZK54.3 [Caenorhabditis elegans] nhr-101 gene37099 556 613 528 1427 1266 1348 29.792797 32.63407216527 28.296729 79.722327 66.923412 81.22113 3.42780917690324e-10 1.23776655433267 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Protein NHR-101, isoform a {ECO:0000313|EMBL:CAC42310.2} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein NHR-101, isoform a [Caenorhabditis elegans] ZK84.2 gene6353 61 63 68 31 18 32 11.7566 11.4748 12.5934 5.88485 3.78414 6.35138 0.00262733005208527 -1.25975877605651 down -- -- -- -- -- [I] Lipid transport and metabolism Emopamil binding protein Protein ZK84.2 {ECO:0000313|EMBL:CCD73327.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK84.2 [Caenorhabditis elegans] asm-3 gene13327 380 466 218 14 15 23 11.468116 13.62845 6.468444 0.413802800000013 0.466778 0.698315 2.07444031481572e-09 -4.36684512767734 down -- -- Molecular Function: hydrolase activity (GO:0016787);; K12350|0|cel:CELE_W03G1.7|asm-3; Protein ASM-3, isoform A; K12350 sphingomyelin phosphodiesterase [EC:3.1.4.12] (A) Sphingolipid metabolism (ko00600);; Lysosome (ko04142) [I] Lipid transport and metabolism Calcineurin-like phosphoesterase Sphingomyelin phosphodiesterase {ECO:0000256|PIRNR:PIRNR000948} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein ASM-3, isoform a [Caenorhabditis elegans] C35C5.8 gene44702 286 290 277 2493 2010 2166 14.2105140000009 13.065600000014 12.659225031 108.273595000004 92.33074 100.06551 1.69535737911053e-53 2.95244243024236 up -- -- -- -- -- -- -- -- Protein C35C5.8, isoform a {ECO:0000313|EMBL:CAC42263.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C35C5.8, isoform a [Caenorhabditis elegans] DH11.2 gene7143 651 575 579 1338 1458 1825 38.003291 33.386708 34.007779 81.05674 93.9952168314 124.79766 4.84900300367434e-09 1.34235212388826 up -- -- -- -- -- -- -- -- Protein DH11.2 {ECO:0000313|EMBL:CAA88939.2} OS=Caenorhabditis elegans PE=4 SV=2 TU Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport Protein DH11.2 [Caenorhabditis elegans] C50F4.8 gene36128 780 878 854 1820 1735 1689 42.2545228 49.24205 45.768175 98.566968 94.216567 90.664759 6.14846160913744e-08 1.04769632995187 up -- -- -- -- -- -- -- -- Protein C50F4.8 {ECO:0000313|EMBL:CAA94743.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C50F4.8 [Caenorhabditis elegans] C44C10.3 gene44770 73 96 70 33 17 27 4.2284672425 5.5059842635 4.016738257 2.07445402742 1.1472963321 1.7118275014 1.78721566372364e-05 -1.64817384767792 down [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; -- -- [R] General function prediction only Sugar (and other) transporter;; Major Facilitator Superfamily Protein C44C10.3 {ECO:0000313|EMBL:CAA93635.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C44C10.3 [Caenorhabditis elegans] ant-1.3 gene19039 200 285 255 130 120 107 16.3291 22.7414 20.3972 10.635 9.93819 9.15566 0.000119442749935909 -1.06553661322433 down -- -- -- K05863|0|cel:CELE_K01H12.2|ant-1.3; Protein ANT-1.3; K05863 solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31 (A) Calcium signaling pathway (ko04020) [C] Energy production and conversion Mitochondrial carrier protein Protein ANT-1.3 {ECO:0000313|EMBL:CAA92472.1} OS=Caenorhabditis elegans PE=2 SV=1 S Function unknown Protein ANT-1.3 [Caenorhabditis elegans] clec-76 gene14174 516 648 243 1268 1425 1647 28.5615 33.44625 12.05592 63.4665 75.4591 79.17062 1.0671082595606e-08 1.61316712865309 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-76 {ECO:0000313|EMBL:CCD71387.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-76 [Caenorhabditis elegans] srr-6 gene34417 145 151 112 325 327 331 6.34882 6.58359 4.79947 15.2348 14.95281 14.56105 8.6421255741061e-07 1.25506785097657 up -- -- -- -- -- -- -- Caenorhabditis protein of unknown function, DUF267 Protein SRR-6 {ECO:0000313|EMBL:CCD64387.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein SRR-6 [Caenorhabditis elegans] nhx-6 gene4755 5 12 5 37 39 46 0.221409874638301 0.3763624676 0.183884531002598 1.2080916043 1.3455520074 1.5141578794 1.06613597803869e-06 2.46002923347591 up [P] Inorganic ion transport and metabolism Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [P] Inorganic ion transport and metabolism Sodium/hydrogen exchanger family Sodium/hydrogen exchanger {ECO:0000256|RuleBase:RU003722} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein NHX-6, isoform b [Caenorhabditis elegans] col-79 gene8084 206 187 231 75 58 55 14.84961 12.51926 16.17295 5.29365 4.27648 3.587843 8.74240041144257e-10 -1.74603670860949 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain CRE-COL-79 protein {ECO:0000313|EMBL:EFO85858.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein COL-79 [Caenorhabditis elegans] H39E23.3 gene38157 470 381 99 2744 3169 2776 7.31215 5.90019 1.51108 41.5782 41.4847 38.9377 1.60196520021417e-62 3.18062471166534 up -- -- -- -- -- -- -- -- Protein H39E23.3 {ECO:0000313|EMBL:CAI79216.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein H39E23.3 [Caenorhabditis elegans] bli-2 gene6187 866 812 1021 246 193 279 47.9749 44.1876 55.9977 13.4282 10.3304 15.1348 2.16179043292754e-20 -1.9250494935059 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein BLI-2 {ECO:0000313|EMBL:CCD64978.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein BLI-2 [Caenorhabditis elegans] F35D11.4 gene5772 236 249 271 142 93 91 43.0859 42.9139 48.393 25.2335 18.1979 17.2401 6.31999501795247e-06 -1.22870593830887 down [F] Nucleotide transport and metabolism -- -- -- -- -- CYTH domain Protein F35D11.4 {ECO:0000313|EMBL:CCD70532.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein F35D11.4 [Caenorhabditis elegans] F46A9.1 gene2461 140 117 176 53 60 43 17.1816 14.26669 21.30519 6.76694234941 7.58541 5.541076 3.08027331584561e-06 -1.48798841259919 down -- -- -- -- -- -- -- -- Protein F46A9.1 {ECO:0000313|EMBL:CAB03106.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F46A9.1 [Caenorhabditis elegans] Y69E1A.2 gene19541 231 333 417 126 150 162 14.4137 20.8826 26.2804 7.9146 9.69172 10.6056 0.0063332963137554 -1.17729690305501 down -- -- -- -- -- -- -- Cytosolic motility protein Protein Y69E1A.2 {ECO:0000313|EMBL:CAA22257.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein Y69E1A.2 [Caenorhabditis elegans] col-95 gene12757 2199 1672 2745 799 672 751 112.251 78.3883 130.045 35.833 28.6258 29.7571 1.89712896178798e-05 -1.58959467877205 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Nematode cuticle collagen N-terminal domain;; Collagen triple helix repeat (20 copies) Protein COL-95 {ECO:0000313|EMBL:CAD66222.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein COL-95 [Caenorhabditis elegans] cpr-1 gene37291 5493 5132 5703 14733 16086 15972 347.311 315.92 348.162 900.531 970.826 981.309 9.3901673790813e-17 1.50463279080505 up -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; K01363|0|cel:CELE_C52E4.1|cpr-1; Protein CPR-1; K01363 cathepsin B [EC:3.4.22.1] (A) Lysosome (ko04142) [O] Posttranslational modification, protein turnover, chaperones Papain family cysteine protease Protein CBR-CPR-1 {ECO:0000313|EMBL:CAP39674.1} OS=Caenorhabditis briggsae PE=3 SV=1 G Carbohydrate transport and metabolism Protein CPR-1 [Caenorhabditis elegans] C53D6.10 gene18772 57 53 67 29 21 13 5.25618 5.16137 5.05456 2.069675 2.395134 1.504863 0.000423625132448743 -1.50616982059072 down -- -- -- -- -- [W] Extracellular structures -- Protein C53D6.10 {ECO:0000313|EMBL:CAH04652.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein C53D6.10 [Caenorhabditis elegans] T22F3.11 gene34001 496 399 348 15154 15537 13031 21.23674 16.66968 14.43091 627.04 659.558 544.646 9.89124423835143e-143 5.1222010304037 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein T22F3.11, isoform a {ECO:0000313|EMBL:CCD70906.1} OS=Caenorhabditis elegans PE=4 SV=2 G Carbohydrate transport and metabolism Protein T22F3.11, isoform a [Caenorhabditis elegans] pmp-5 gene35017 257 265 236 656 633 623 7.9484897 8.37923 7.189197 20.33742 21.00138811051 20.879834 2.47945849181013e-09 1.32080774645241 up [R] General function prediction only Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; -- -- [IR] Lipid transport and metabolism;; General function prediction only ABC transporter transmembrane region 2;; ABC transporter;; NACHT domain Protein PMP-5, isoform a {ECO:0000313|EMBL:CCD71212.1} OS=Caenorhabditis elegans PE=3 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein PMP-5, isoform a [Caenorhabditis elegans] cutl-18 gene36939 137 160 158 68 78 75 3.182598 3.802605 3.738476 1.633345 1.936596 1.985657 0.000939487482409382 -1.05560924386983 down -- -- -- -- -- -- -- Zona pellucida-like domain;; PAN domain Protein CUTL-18 {ECO:0000313|EMBL:CAA98485.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CUTL-18 [Caenorhabditis elegans] lys-7 gene33944 8366 8133 6909 24351 22491 26708 763.77 700.583 601.444 2175.6 2080.18 2461.9 1.48560961466129e-18 1.63788102678169 up -- -- -- -- -- -- -- -- Protein LYS-7 {ECO:0000313|EMBL:CCD62480.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein LYS-7 [Caenorhabditis elegans] ZK488.5 gene33051 49 38 48 18 12 25 1.92088 1.44645 1.83432 0.710344 0.499235 1.03735 0.00552584185993895 -1.31008259059958 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein ZK488.5 {ECO:0000313|EMBL:CCD71524.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK488.5 [Caenorhabditis elegans] T05B4.13 gene34165 92 156 91 1095 925 1031 8.056982406 10.32083338 5.4991614925 72.73031 66.6681632 71.17075938 4.47755146573925e-48 3.15710803526247 up -- -- -- -- -- -- -- ShK domain-like Protein T05B4.13 {ECO:0000313|EMBL:CCD70838.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only T05B4.13 [Caenorhabditis elegans] Y37D8A.19 gene13001 965 1013 1366 685 376 380 1664.22 1550.23 2242.81 1194.13 1014.69 828.475 0.000723841281390528 -1.23048656711552 down -- -- -- -- -- -- -- -- Protein Y37D8A.19 {ECO:0000313|EMBL:CAA21542.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein Y37D8A.19 [Caenorhabditis elegans] ZK1307.4 gene7734 38 57 61 20 21 22 19.82498297381 25.7071972568 29.82916379163 11.154353628 13.4475378627 12.562430912583 0.00319296711530391 -1.32198101800747 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT51838.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein ZK1307.4 [Caenorhabditis elegans] C25A11.1 gene43950 37 37 50 99 87 103 3.740163676107 2.7455440149 4.44653716 7.29541681 13.04551535 9.63959 0.000995199981334937 1.20591573350898 up -- -- -- -- -- -- -- -- Protein C25A11.1 {ECO:0000313|EMBL:CCD62267.1} OS=Caenorhabditis elegans PE=4 SV=2 Z Cytoskeleton Protein C25A11.1 [Caenorhabditis elegans] W05B2.2 gene12585 89 74 57 36 36 35 1.017551 0.812603 0.6387113 0.387691 0.3869932967 0.3470154 0.00929318556246619 -1.05381235414954 down -- -- Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; -- -- [O] Posttranslational modification, protein turnover, chaperones Kunitz/Bovine pancreatic trypsin inhibitor domain;; Lustrin, cysteine-rich repeated domain;; EB module Protein W05B2.2 {ECO:0000313|EMBL:CAB63320.3} OS=Caenorhabditis elegans PE=4 SV=3 Z Cytoskeleton Protein W05B2.2 [Caenorhabditis elegans] T24C4.8 gene9577 31 39 34 15 8 13 3.377875 4.5602108 3.513379 1.8688818154 0.993319 1.922876 0.00283044267051989 -1.54489159747535 down -- -- -- -- -- -- -- Tight junction protein, Claudin-like Protein T24C4.8 {ECO:0000313|EMBL:CCD69962.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein T24C4.8 [Caenorhabditis elegans] grd-2 gene40641 214 223 184 80 80 83 4.2248 4.35586 3.62914 1.57833 1.60121 1.65755 1.57714879877582e-06 -1.36736234786808 down -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; -- -- -- -- Ground-like domain;; Hint module Protein GRD-2 {ECO:0000313|EMBL:CAB04405.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein GRD-2 [Caenorhabditis elegans] M70.1 gene13710 112 119 137 49 60 63 2.371536 2.60909156761 2.9715037639 1.09912203 1.4125458946 1.5950128185 0.00106260529180819 -1.11125149047389 down -- -- -- -- -- -- -- Domain of unknown function Protein M70.1, isoform b {ECO:0000313|EMBL:CDH93481.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown M70.1, isoform b [Caenorhabditis elegans] col-184 gene45386 7747 8546 14359 3533 2779 3748 484.47125089 517.18384849 883.65456094 212.1464139 164.60787343 222.50546388 0.00540415331379303 -1.62264132503459 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA03972} OS=Caenorhabditis japonica PE=4 SV=2 W Extracellular structures C. briggsae CBR-COL-184 protein [Caenorhabditis briggsae] folt-2 gene33710 289 332 238 693 557 495 15.7814945596428 17.7418340407703 12.533384746823 36.1687026529347 29.6915122742228 26.5807928447884 4.74237363459286e-05 1.00850193277194 up -- -- Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; -- -- [H] Coenzyme transport and metabolism Reduced folate carrier Putative uncharacterized protein {ECO:0000313|EMBL:EGT30842.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein FOLT-2 [Caenorhabditis elegans] lact-4 gene7306 4833 4406 5042 15302 14729 17323 340.46898 294.41319722128 314.28493221 1094.073084 995.185000000626 1180.40984 1.51930355929207e-21 1.71501662826129 up [V] Defense mechanisms -- -- -- -- -- Beta-lactamase Protein LACT-4 {ECO:0000313|EMBL:CAA91413.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein LACT-4 [Caenorhabditis elegans] aqp-8 gene42204 1699 1850 2091 1015 809 755 121.943584 127.8475133995 148.682227 64.53380667961 49.426786 46.883297025 1.81767458296364e-09 -1.14376277513048 down [G] Carbohydrate transport and metabolism Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; K09886|4.07397e-180|cel:CELE_K02G10.7|aqp-8; Protein AQP-8, isoform A; K09886 aquaglyceroporin related protein, invertebrate (A) -- [G] Carbohydrate transport and metabolism Major intrinsic protein Protein AQP-8, isoform b {ECO:0000313|EMBL:CCD68566.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein AQP-8, isoform b [Caenorhabditis elegans] Y71G12B.18 gene284 358 271 328 170 107 103 27.9045103303 20.31590762136 24.50610477716 13.07710375863 8.76891369325 8.5547315955 1.29552857667456e-07 -1.3482562123605 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein Y71G12B.18, isoform a {ECO:0000313|EMBL:CCD67988.1} OS=Caenorhabditis elegans PE=4 SV=3 V Defense mechanisms Protein Y71G12B.18 [Caenorhabditis elegans] upp-1 gene11500 2712 2956 2882 1460 1408 1337 166.94289 179.75944317 177.89899 87.8514250000024 86.0100786 82.20559219 2.80785216799845e-08 -1.03798907288404 down [F] Nucleotide transport and metabolism Molecular Function: catalytic activity (GO:0003824);; Biological Process: nucleoside metabolic process (GO:0009116);; K00757|0|cel:CELE_ZK783.2|upp-1; Protein UPP-1; K00757 uridine phosphorylase [EC:2.4.2.3] (A) Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983) [F] Nucleotide transport and metabolism Phosphorylase superfamily Protein UPP-1 {ECO:0000313|EMBL:CCD65249.1} OS=Caenorhabditis elegans PE=1 SV=2 S Function unknown Protein UPP-1 [Caenorhabditis elegans] T19C4.5 gene36857 199 202 167 455 317 436 8.941190313784 10.0229918324 8.32845377254 23.8503143024 15.72626 23.0367200001656 2.21156404864841e-05 1.0745191036946 up -- -- Molecular Function: oxygen binding (GO:0019825);; Molecular Function: heme binding (GO:0020037);; -- -- -- -- Globin Protein T19C4.5, isoform a {ECO:0000313|EMBL:CAP09186.1} OS=Caenorhabditis elegans PE=3 SV=1 C Energy production and conversion Protein T19C4.5, isoform a [Caenorhabditis elegans] Y51H7C.1 gene4675 585 805 929 253 374 260 16.227777 19.308231 22.32924 5.6993096 7.810779665072 4.817104 6.93914106405748e-05 -1.40035567886365 down -- -- -- -- -- -- -- -- Protein Y51H7C.1 {ECO:0000313|EMBL:CCD71787.1} OS=Caenorhabditis elegans PE=4 SV=1 A RNA processing and modification Protein Y51H7C.1 [Caenorhabditis elegans] F13A7.1 gene39154 90 131 116 40 50 56 6.68469 9.85529 8.90419 2.99365 4.03952 4.37831 0.00043152598581956 -1.2198445515165 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F13A7.1 [Caenorhabditis elegans] C07C7.1 gene18833 13 17 5 35 22 37 0.977085553 1.290090843521 0.402529 2.67745131788 1.73946117022 2.9175830967 0.0091348526389031 1.4130994047671 up -- -- -- -- -- -- -- -- Protein C07C7.1 {ECO:0000313|EMBL:CAA92587.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C07C7.1 [Caenorhabditis elegans] cat-4 gene36557 4442 4319 2569 1427 1018 1064 335.90206 328.777 197.35100724331 111.191 84.0687000374454 91.5659191379 8.66082755760549e-05 -1.70496865238333 down [H] Coenzyme transport and metabolism -- K01495|3.35098e-165|cel:CELE_F32G8.6|cat-4; Protein CAT-4; K01495 GTP cyclohydrolase I [EC:3.5.4.16] (A) Folate biosynthesis (ko00790) [H] Coenzyme transport and metabolism GTP cyclohydrolase I;; QueF-like protein CBN-CAT-4 protein {ECO:0000313|EMBL:EGT48556.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 S Function unknown Protein CAT-4 [Caenorhabditis elegans] dgat-2 gene39686 300 264 167 667 519 621 20.5561 17.4543 11.2959 44.5671 36.4374 42.5744 1.17600660149103e-08 1.29183362271918 up -- -- Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [I] Lipid transport and metabolism Diacylglycerol acyltransferase Protein DGAT-2 {ECO:0000313|EMBL:CAB04533.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein DGAT-2 [Caenorhabditis elegans] K11H12.4 gene13374 325 390 443 186 188 93 17.6295 20.5309 23.3198 10.0008 10.2532 5.14945 5.0372951161076e-06 -1.32508470988553 down -- -- -- -- -- -- -- Transmembrane glycoprotein Protein K11H12.4 {ECO:0000313|EMBL:CCD70973.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein K11H12.4 [Caenorhabditis elegans] gln-3 gene29888 4184 3155 3696 7382 8782 9119 178.4562531374 125.3806020955 153.566480048814 288.85023939692 365.155069131 384.159440841 8.59363588918537e-11 1.18178570947308 up [E] Amino acid transport and metabolism Molecular Function: glutamate-ammonia ligase activity (GO:0004356);; Biological Process: glutamine biosynthetic process (GO:0006542);; Biological Process: nitrogen compound metabolic process (GO:0006807);; K01915|0|cbr:CBG13820|Cbr-gln-3; C. briggsae CBR-GLN-3 protein; K01915 glutamine synthetase [EC:6.3.1.2] (A) Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; Glyoxylate and dicarboxylate metabolism (ko00630);; Nitrogen metabolism (ko00910);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Glutamine synthetase, catalytic domain;; Glutamine synthetase, beta-Grasp domain Glutamine synthetase {ECO:0000256|RuleBase:RU004356} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein GLN-3, isoform a [Caenorhabditis elegans] clec-31 gene39343 5 12 15 34 24 38 0.344383 0.814212 0.987246 2.319739 1.675117 2.71495 0.00337465851872186 1.57068491605519 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-31 {ECO:0000313|EMBL:CAB04414.2} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-31 [Caenorhabditis elegans] elo-6 gene15453 2202 2364 1858 8978 6466 6848 225.81120980923 236.930259744627 183.678422754 943.448271304623 731.3862109692 796.85908 1.41232588481794e-11 1.78072442557061 up -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [I] Lipid transport and metabolism GNS1/SUR4 family Elongation of very long chain fatty acids protein {ECO:0000256|RuleBase:RU361115} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 S Function unknown Protein ELO-6 [Caenorhabditis elegans] daf-28 gene40413 198 194 96 459 474 459 22.09344054 20.1188996854 12.49261 49.0883139151 53.1663344712 49.9085398984 1.82576180537788e-10 1.49919532680442 up -- -- -- -- -- -- -- Nematode insulin-related peptide beta type Protein DAF-28 {ECO:0000313|EMBL:CAB61047.2} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein DAF-28 [Caenorhabditis elegans] C31H1.1 gene16265 105 119 137 39 65 54 3.912214 4.5248818175 5.180329 1.547782163 2.6259548978 2.30371385639 0.000382366674471639 -1.20568538091014 down -- -- -- -- -- -- -- -- Protein C31H1.1 {ECO:0000313|EMBL:CCD64155.2} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein C31H1.1 [Caenorhabditis elegans] F43C9.1 gene42234 95 101 74 257 197 241 4.990089 4.459628 3.019885 11.01381 7.812536 9.648791 1.1131126360208e-06 1.35022084477018 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- F-box domain Protein F43C9.1 {ECO:0000313|EMBL:CCD67082.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein F43C9.1 [Caenorhabditis elegans] pals-3 gene3691 14 15 4 40 55 52 0.6620855 0.713235630834 0.23851117117 1.642793 1.759475 2.767959466 3.5801898507754e-06 2.14362248257714 up -- -- -- -- -- -- -- -- Protein C17H1.4 {ECO:0000313|EMBL:CAB07168.2} OS=Caenorhabditis elegans PE=4 SV=2 -- -- Protein C17H1.4 [Caenorhabditis elegans] Y49G5A.1 gene34503 742 678 225 71 56 70 121.573 104.233 35.7428 11.4675 9.81177 11.7767 0.00315498499884255 -3.07471924576161 down -- -- Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; -- -- [O] Posttranslational modification, protein turnover, chaperones Kunitz/Bovine pancreatic trypsin inhibitor domain Protein Y49G5A.1 {ECO:0000313|EMBL:CCD61496.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein Y49G5A.1 [Caenorhabditis elegans] cyp-13A12 gene13024 46 18 33 127 82 165 1.900778 0.71426703922 1.28528987608 5.20445 3.51384 7.046101 0.00123618604031585 1.93127353813876 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17861|0|cel:CELE_F14F7.3|cyp-13A12; Protein CYP-13A12; K17861 cytochrome P450, family 13 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-13A12 {ECO:0000313|EMBL:CAB04113.1} OS=Caenorhabditis elegans PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-13A12 [Caenorhabditis elegans] C10G11.6 gene1492 1852 1854 2093 4441 4067 3904 77.3094978668681 78.2457277337722 85.87163034074 178.35573041261 166.572767 170.4701438 3.03028350711557e-09 1.08324413858387 up -- -- -- -- -- -- -- -- Protein C10G11.6, isoform b {ECO:0000313|EMBL:CCD64189.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C10G11.6, isoform b [Caenorhabditis elegans] math-15 gene4835 56 54 61 315 235 259 3.6878955304 3.656222182333 4.16804260041 21.88960929445 15.46773632782 18.9909510999 1.95025643468229e-16 2.22723833878307 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- MATH domain Protein MATH-15 {ECO:0000313|EMBL:CCD64669.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein MATH-15 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_557 45 64 28 127 106 102 2.6385678751 3.692716762 1.599322634 7.5092429052 6.4234361447 6.39220427468 0.000245291971595247 1.27725023932437 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- BTB/POZ domain Protein BTB-21 {ECO:0000313|EMBL:CCD64884.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription PREDICTED: speckle-type POZ protein A-like [Fopius arisanus] col-7 gene1861 282 398 363 80 92 61 10.06306 14.43437 13.30003 3.18166 3.125051 2.49861 8.16669620034916e-16 -2.17617812221477 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-62 {ECO:0000313|EMBL:CAB01958.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-7 [Caenorhabditis elegans] Y24D9B.1 gene14296 91 115 129 47 43 51 3.03298 3.79239 4.31424 1.51286 1.36373 1.63594 0.000271525329220755 -1.26266297639152 down -- -- -- -- -- -- -- Zc3h12a-like Ribonuclease NYN domain Protein Y24D9B.1 {ECO:0000313|EMBL:CCD69521.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein Y24D9B.1 [Caenorhabditis elegans] C06B3.6 gene38074 2271 1868 3332 4209 5016 6286 248.1740900874 195.656 351.4100731511 454.98 559.67400592581 714.4730366258 0.00364476025038495 1.03909683532894 up -- -- -- -- -- -- -- -- Protein C06B3.6 {ECO:0000313|EMBL:CAB01116.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C06B3.6 [Caenorhabditis elegans] ugt-36 gene35227 47 72 30 378 299 373 2.056439 3.1570416256 1.3145597848 16.7595 13.584813 17.49044 1.73751385867464e-26 2.80465477854367 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-36 {ECO:0000313|EMBL:CCD64426.1} OS=Caenorhabditis elegans PE=4 SV=2 P Inorganic ion transport and metabolism Protein UGT-36 [Caenorhabditis elegans] F58H1.2 gene37262 348 284 239 198 84 124 57.8315 44.532 38.8543 32.1956 15.0106 21.1341 0.00453834234122592 -1.11656599781867 down -- -- -- -- -- -- -- -- Protein F58H1.2 {ECO:0000313|EMBL:CAB00105.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F58H1.2 [Caenorhabditis elegans] ech-9 gene19290 218 240 173 746 566 627 9.601086543 10.976316874 7.9575340667 34.5963505179 27.0578251104 31.2477591284 2.88422713995567e-13 1.6056883664473 up [I] Lipid transport and metabolism Molecular Function: 3-hydroxyacyl-CoA dehydrogenase activity (GO:0003857);; Biological Process: fatty acid metabolic process (GO:0006631);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00022|0|cel:CELE_F01G10.3|ech-9; Protein ECH-9; K00022 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] (A) Fatty acid elongation (ko00062);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; Butanoate metabolism (ko00650);; Fatty acid metabolism (ko01212) [I] Lipid transport and metabolism 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain;; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain;; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Protein ECH-9, isoform a {ECO:0000313|EMBL:CAB02892.2} OS=Caenorhabditis elegans PE=1 SV=2 V Defense mechanisms Protein ECH-9 [Caenorhabditis elegans] far-2 gene11999 12291 14783 20799 8257 7722 7380 2432.21 2731.65 3941.71 1570.06 1566.84 1469.66 0.00865124675643818 -1.05016430235165 down -- -- Molecular Function: lipid binding (GO:0008289);; -- -- -- -- Nematode fatty acid retinoid binding protein (Gp-FAR-1) Protein CBR-FAR-2 {ECO:0000313|EMBL:CAP27057.1} OS=Caenorhabditis briggsae PE=4 SV=1 T Signal transduction mechanisms Protein FAR-2 [Caenorhabditis elegans] ZC190.2 gene35804 148 181 137 56 50 42 9.0057342444 11.5837920640003 8.288677167 3.46203767200003 3.02867068996 2.620456 7.02806123124857e-08 -1.6686037777428 down -- -- -- -- -- -- -- -- Protein ZC190.2 {ECO:0000313|EMBL:CCD70117.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZC190.2 [Caenorhabditis elegans] ddn-1 gene35827 633 470 218 1226 1209 1700 18.99712883552 16.0136922869355 7.10208389 41.42136008 40.437329044 65.16461632 2.17708677205496e-05 1.63325511644204 up -- -- -- -- -- -- -- -- Protein B0507.10 {ECO:0000313|EMBL:CCD62075.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein B0507.10 [Caenorhabditis elegans] fat-3 gene19075 2633 2608 2634 11176 10732 11773 126.18424544 126.62179783 125.74323716 539.76527 512.34466522 580.63603 2.48090685467898e-31 2.08242343339965 up [I] Lipid transport and metabolism Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Fatty acid desaturase;; Cytochrome b5-like Heme/Steroid binding domain CBN-FAT-3 protein {ECO:0000313|EMBL:EGT37896.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein FAT-3, isoform a [Caenorhabditis elegans] col-127 gene19670 341 390 242 575 679 787 10.94908 11.4072 7.17311 18.13151 20.595 25.75961 4.15255262122146e-05 1.05607301013566 up -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Putative uncharacterized protein {ECO:0000313|EMBL:EFO93747.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 W Extracellular structures hypothetical protein CRE_12586 [Caenorhabditis remanei] C08E8.10 gene39916 229 242 194 558 480 543 68.6455 54.880891 48.10928 132.844969 115.24658618 145.0892 8.46315811921716e-08 1.23555295151294 up -- -- -- -- -- -- -- -- Protein C08E8.10 {ECO:0000313|EMBL:CAQ35016.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C08E8.10 [Caenorhabditis elegans] fbxc-7 gene4499 62 82 41 129 147 136 3.560383 3.187677 1.648085 5.85059 6.8649 6.076 0.000506085964314963 1.14265326263525 up -- -- -- -- -- -- -- Domain of unknown function (DUF3557) Protein FBXC-7 {ECO:0000313|EMBL:CCD66350.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein FBXC-7 [Caenorhabditis elegans] msp-113 gene15306 170 292 294 107 118 133 85.6261 130.645 139.644 51.1249 67.1304 69.7518 0.00874872189493929 -1.0918817397043 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein MSP-31 [Caenorhabditis elegans] F09C6.1 gene39359 24 33 23 76 56 73 2.52466 3.35744 2.37658 7.80283 6.19879 7.73472 0.00102122048908044 1.34408335559932 up -- -- -- -- -- -- -- Fascin domain Protein F09C6.1 {ECO:0000313|EMBL:CAB04067.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein F09C6.1 [Caenorhabditis elegans] nspe-1 gene8737 9 11 6 55 39 53 180.48 221.388 135.719 1280.23 1561.12 1802.55 1.36198538121326e-07 2.48603424759783 up -- -- -- -- -- -- -- Protein of unknown function (DUF1412) Protein NSPE-1 {ECO:0000313|EMBL:CAB54404.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein NSPE-1 [Caenorhabditis elegans] clec-74 gene14171 2456 2702 1202 515 312 359 119.2514 128.0606 56.2345 24.4931 15.52167 17.81475 0.000326707477912423 -2.43652371946592 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-74 {ECO:0000313|EMBL:CCD71968.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-74 [Caenorhabditis elegans] thn-2 gene20130 197 141 299 652 552 599 21.8098511816 14.923452 31.45762 66.72839 62.42038 63.898517 2.70646654936463e-11 1.48501006156102 up -- -- -- -- -- -- -- Thaumatin family Protein THN-2 {ECO:0000313|EMBL:CAA94600.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein THN-2 [Caenorhabditis elegans] cyp-33C8 gene34043 571 732 685 1492 1241 1439 22.26547 28.83141 26.85611 59.7099 50.7868 59.6998 1.09424469299829e-07 1.05540006982568 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17955|0|cel:CELE_R08F11.3|cyp-33C8; Protein CYP-33C8; K17955 cytochrome P450, family 33 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-33C8 {ECO:0000313|EMBL:CCD72308.1} OS=Caenorhabditis elegans PE=3 SV=1 G Carbohydrate transport and metabolism Protein CYP-33C8 [Caenorhabditis elegans] rtel-1 gene2875 2490 2578 2684 5447 5034 5749 128.295829689 125.363232221 111.6535676572 324.8966978741 320.4088920322 372.5978384757 8.64560940467209e-09 1.05181153121156 up [KL] Transcription;; Replication, recombination and repair Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP-dependent DNA helicase activity (GO:0004003);; Molecular Function: ATP binding (GO:0005524);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: ATP-dependent helicase activity (GO:0008026);; Molecular Function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818);; K11136|0|cel:CELE_F25H2.13|rtel-1; Protein RTEL-1; K11136 regulator of telomere elongation helicase 1 [EC:3.6.4.12] (A) -- [L] Replication, recombination and repair Helicase C-terminal domain;; DEAD_2;; DEAD/DEAH box helicase Putative uncharacterized protein {ECO:0000313|EMBL:EGT39720.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein RTEL-1 [Caenorhabditis elegans] C45E5.1 gene16145 9 15 11 147 126 136 0.724831 1.20439 0.850275 11.6544 9.99309 11.1354 3.8846057292802e-22 3.53336481565578 up [G] Carbohydrate transport and metabolism -- -- -- [P] Inorganic ion transport and metabolism Haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like;; Mitochondrial PGP phosphatase Protein C45E5.1 {ECO:0000313|EMBL:CCD67369.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C45E5.1 [Caenorhabditis elegans] T27A3.5 gene1404 127 156 176 74 80 75 6.99903 8.64045 9.84892 4.08488 4.44392 4.17697 0.00144478076176711 -1.01731760699587 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase Protein T27A3.5 {ECO:0000313|EMBL:CCD72005.1} OS=Caenorhabditis elegans PE=4 SV=3 H Coenzyme transport and metabolism Protein T27A3.5 [Caenorhabditis elegans] bli-6 gene17347 3188 3780 3868 1061 1284 1056 199.469 220.62 229.195 60.6889 73.6437 57.147 4.28302893442075e-21 -1.6857121352093 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein BLI-6 {ECO:0000313|EMBL:CCD74181.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein BLI-6 [Caenorhabditis elegans] C46H11.2 gene1091 316 372 239 816 736 837 16.48197 18.98375 12.264035 43.168554 39.16912 45.00596 2.10933113419254e-10 1.35251511408411 up -- -- Molecular Function: N,N-dimethylaniline monooxygenase activity (GO:0004499);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism Flavin-binding monooxygenase-like;; Pyridine nucleotide-disulphide oxidoreductase;; FAD dependent oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; FAD-NAD(P)-binding;; HI0933-like protein;; L-lysine 6-monooxygenase (NADPH-requiring);; FAD binding domain;; Glucose inhibited division protein A;; Pyridine nucleotide-disulphide oxidoreductase;; Thi4 family;; NAD(P)-binding Rossmann-like domain;; Lycopene cyclase protein;; Putative NAD(P)-binding;; FAD binding domain Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein C46H11.2 [Caenorhabditis elegans] Y54G2A.45 gene13851 2008 2284 1274 744 632 687 164.6750231855 180.7550116092 101.47900904671 58.6472119582 56.2254145309 58.44720641578 0.000549347797999427 -1.44513381562599 down -- -- Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Lipase (class 3) Protein Y54G2A.45, isoform a {ECO:0000313|EMBL:CCD83539.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein Y54G2A.45 [Caenorhabditis elegans] C15A11.4 gene1859 576 598 480 204 173 202 31.9141 31.053 26.07745 11.52474 10.83549 12.26226 1.46322683055595e-11 -1.52819252572109 down -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- -- -- Sulfite exporter TauE/SafE Protein C15A11.4 {ECO:0000313|EMBL:CAB01963.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein C15A11.4 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_607 55 61 59 145 153 142 2.86598 3.181 3.01729 7.74714 8.66411 8.26635 3.44005799035234e-05 1.31616107429386 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Protein NHR-271 {ECO:0000313|EMBL:CAB07282.2} OS=Caenorhabditis elegans PE=3 SV=2 O Posttranslational modification, protein turnover, chaperones PREDICTED: hormone receptor 4 [Musca domestica] ZK1248.5 gene6268 58 92 81 29 40 16 4.2755 6.81704 5.97964 2.26584 3.21974 1.37783 0.000437721448450493 -1.4560747307148 down -- -- -- -- -- -- -- Protein of unknown function (DUF1248) Protein ZK1248.5 {ECO:0000313|EMBL:CCD72507.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZK1248.5 [Caenorhabditis elegans] best-24 gene11572 231 296 274 1484 1506 1619 6.09385623700011 8.04077293 7.41535891812942 41.2307519100938 41.76084839 47.646353 3.04259862806835e-37 2.51088650521064 up -- -- -- -- -- [R] General function prediction only Bestrophin, RFP-TM, chloride channel Putative uncharacterized protein {ECO:0000313|EMBL:EFP04239.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein BEST-24 [Caenorhabditis elegans] F21C10.10 gene35977 1592 1410 1975 9974 9099 12203 189.1334 158.11347 223.5136 1178.1405 1127.2507 1482.6532 1.72815597699559e-25 2.63698317410427 up -- -- -- -- -- -- -- 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Protein F21C10.10 {ECO:0000313|EMBL:CCD61441.1} OS=Caenorhabditis elegans PE=4 SV=2 Z Cytoskeleton Protein F21C10.10 [Caenorhabditis elegans] gst-38 gene38929 1262 1306 958 136 92 99 166.601 168.948 126.6 17.4013 12.4715 13.0904 3.15043770157445e-34 -3.44496059858968 down -- -- Molecular Function: protein binding (GO:0005515);; K00799|3.36831e-154|cel:CELE_F35E8.8|gst-38; Protein GST-38; K00799 glutathione S-transferase [EC:2.5.1.18] (A) Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982) [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain Protein GST-38 {ECO:0000313|EMBL:CAB04293.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein GST-38 [Caenorhabditis elegans] gst-42 gene44780 944 939 728 371 414 379 85.6829 86.2187 65.3386 32.17912 37.4808 33.25181 2.17078625514735e-08 -1.17909981554493 down [O] Posttranslational modification, protein turnover, chaperones Molecular Function: protein binding (GO:0005515);; Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; Biological Process: cell redox homeostasis (GO:0045454);; K01800|7.50361e-155|cel:CELE_D1053.1|gst-42; Protein GST-42; K01800 maleylacetoacetate isomerase [EC:5.2.1.2] (A) Tyrosine metabolism (ko00350) [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutaredoxin;; Glutathione S-transferase, C-terminal domain CRE-GST-42 protein {ECO:0000313|EMBL:EFO91240.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein GST-42 [Caenorhabditis elegans] got-2.2 gene42813 5861 5254 5475 11044 11385 11202 231.51174 203.3587035 211.55577325177 428.80049 428.767428000214 430.76283 8.52016059843095e-08 1.00519399913943 up [E] Amino acid transport and metabolism Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; K14455|0|cbr:CBG05011|Hypothetical protein CBG05011; K14455 aspartate aminotransferase, mitochondrial [EC:2.6.1.1] (A) Alanine, aspartate and glutamate metabolism (ko00250);; Cysteine and methionine metabolism (ko00270);; Arginine and proline metabolism (ko00330);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; Phenylalanine, tyrosine and tryptophan biosynthesis (ko00400);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Aminotransferase class I and II Aspartate aminotransferase {ECO:0000256|RuleBase:RU000480} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein GOT-2.2, isoform a [Caenorhabditis elegans] ftn-1 gene35385 1106 945 456 2238 2172 2864 181.2734 143.82289 74.60702 362.9416 377.892 481.8018 5.77679902767029e-07 1.52384603320204 up [P] Inorganic ion transport and metabolism Biological Process: cellular iron ion homeostasis (GO:0006879);; Molecular Function: ferric iron binding (GO:0008199);; -- -- [P] Inorganic ion transport and metabolism Ferritin-like domain Ferritin {ECO:0000256|RuleBase:RU361145} OS=Caenorhabditis elegans PE=1 SV=2 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein FTN-1 [Caenorhabditis elegans] math-18 gene4943 1340 1367 1054 3184 3168 3600 44.92130716 44.164078699 35.01548228 105.909949888 109.179277858 121.70406114 1.56248420702326e-14 1.39033832965002 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- MATH domain Protein MATH-18 {ECO:0000313|EMBL:CCD66471.1} OS=Caenorhabditis elegans PE=4 SV=2 P Inorganic ion transport and metabolism Protein MATH-18 [Caenorhabditis elegans] Y105C5A.24 gene28491 255 272 204 506 590 588 8.304479 8.745683 6.512058 16.02147436 18.41376 18.550628 1.84325142862497e-07 1.19066568801515 up [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; K04427|0|cel:CELE_Y105C5A.24|Y105C5A.24; Protein Y105C5A.24; K04427 mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] (A) MAPK signaling pathway (ko04010);; Wnt signaling pathway (ko04310) [T] Signal transduction mechanisms Protein kinase domain;; Protein tyrosine kinase Protein Y105C5A.24 {ECO:0000313|EMBL:CAB55004.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein Y105C5A.24 [Caenorhabditis elegans] dod-17 gene20336 3307 3665 1738 956 636 713 235.697 262.339 123.398 69.3456 48.6807 54.9533 0.00108703658382564 -1.93141401083159 down -- -- -- -- -- -- -- CUB-like domain Protein DOD-17 {ECO:0000313|EMBL:CAB03521.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein DOD-17 [Caenorhabditis elegans] ssq-2 gene14803 691 716 849 283 344 401 31.97077 32.59224 39.86954 12.06383 14.77369 16.11305 1.11789393055854e-07 -1.14785656224647 down -- -- -- -- -- -- -- -- Protein SSQ-2 {ECO:0000313|EMBL:CCD63838.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein SSQ-2 [Caenorhabditis elegans] vap-2 gene44454 411 432 493 179 184 257 17.8187268700004 19.0553174670219 21.7972574232 7.8350986158 8.129390535307 11.4767942 2.92663557493494e-06 -1.12151510630532 down -- -- -- -- -- [S] Function unknown Cysteine-rich secretory protein family Protein SCL-22 {ECO:0000313|EMBL:CAA92136.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein SCL-22 [Caenorhabditis elegans] T26H5.10 gene38709 44 48 64 161 120 116 23.08602 25.4449 45.93961 106.62365 106.24462 72.22024 4.72358758738495e-05 1.33226928311241 up -- -- -- -- -- -- -- -- Protein T26H5.10 {ECO:0000313|EMBL:CAJ85765.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein T26H5.10 [Caenorhabditis elegans] W05H9.1 gene42820 2827 2613 2058 4882 4908 5645 107.187403 98.825219288 78.979878403 193.455484 196.239056703 247.66099 2.09481855626589e-08 1.02798988386334 up -- -- Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; -- -- -- -- -- Protein W05H9.1, isoform a {ECO:0000313|EMBL:CCD64548.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein W05H9.1, isoform a [Caenorhabditis elegans] F28H7.3 gene36647 1108 1137 898 301 265 228 105.49 100.355 79.9405 28.3812 26.6289 23.7803 9.70508848656935e-23 -1.99906143396165 down -- -- Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Lipase (class 3) Protein F28H7.3 {ECO:0000313|EMBL:CAA96636.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F28H7.3 [Caenorhabditis elegans] col-145 gene36006 2293 2087 1865 1053 1090 840 125.863 102.67 93.3928 51.7962 52.4094 38.8072 1.10165385440804e-08 -1.08018617231752 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain CBN-COL-145 protein {ECO:0000313|EMBL:EGT37622.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein COL-145 [Caenorhabditis elegans] C49C8.1 gene18638 31 36 32 17 11 9 1.1382500188893 1.30488048197 1.17649 0.630518 0.4724922033 0.348829 0.00657535852958602 -1.43485008414152 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein kinase domain;; Protein tyrosine kinase Protein C49C8.1 {ECO:0000313|EMBL:CCD67641.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown C49C8.1 [Caenorhabditis elegans] pals-2 gene3689 46 40 25 132 154 168 1.92032349532 1.5367947166558 0.929184200001671 4.950261947 5.86726040003827 6.51288557 1.80468433430245e-10 2.01899860274535 up -- -- -- -- -- -- -- -- Protein C17H1.3 {ECO:0000313|EMBL:CAB07167.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C17H1.3 [Caenorhabditis elegans] C42D4.13 gene18070 536 461 316 259 146 179 75.2991500000001 58.3668000002898 40.68595 33.68202 18.84633 24.34407 0.00480364220784616 -1.18345136437958 down -- -- -- -- -- -- -- -- Protein C42D4.13, isoform a {ECO:0000313|EMBL:CDK13385.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only C42D4.13, isoform a [Caenorhabditis elegans] F09F7.6 gene10840 88 111 82 188 173 268 293.981 352.973 281.738 672.13 998.03 1260.45 0.00175342751050295 1.14948738975414 up -- -- -- -- -- -- -- -- Protein F09F7.6 {ECO:0000313|EMBL:CCD68389.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F09F7.6 [Caenorhabditis elegans] dao-4 gene44216 186 198 181 50 40 54 20.827 21.5285 19.8946 5.5524 4.71723 6.16568 1.63424741037586e-11 -1.98620030512679 down -- -- -- -- -- -- -- -- Protein DAO-4 {ECO:0000313|EMBL:CAA88978.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein DAO-4 [Caenorhabditis elegans] ges-1 gene33260 1215 1138 846 2696 2473 2799 40.67055 38.94049 28.67665 92.1960761 88.022404 101.762029 1.65441628247957e-12 1.30286954540031 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; K01044|0|cel:CELE_R12A1.4|ges-1; Protein GES-1; K01044 carboxylesterase 1 [EC:3.1.1.1] (A) Drug metabolism - other enzymes (ko00983) [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family CRE-GES-1 protein {ECO:0000313|EMBL:EFO87676.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein GES-1 [Caenorhabditis elegans] C55B7.3 gene1556 66 97 105 36 43 44 3.9253 5.66249 6.13761 2.14834 2.50444 2.59225 0.00251241349821095 -1.13725617449436 down -- -- Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain;; Tyrosine phosphatase family Protein C55B7.3 {ECO:0000313|EMBL:CCD68090.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein C55B7.3 [Caenorhabditis elegans] F19C7.4 gene14403 88 77 49 31 36 31 3.603051 3.17530309971 1.994695 1.306036 1.568508 1.392054 0.00670479568584339 -1.1401703975879 down -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; -- -- [OR] Posttranslational modification, protein turnover, chaperones;; General function prediction only Serine carboxypeptidase S28 Protein F19C7.4 {ECO:0000313|EMBL:CCD69715.1} OS=Caenorhabditis elegans PE=4 SV=2 W Extracellular structures Protein F19C7.4 [Caenorhabditis elegans] gbh-2 gene7309 254 290 321 820 709 973 12.26612 14.07266 15.00195 38.9899 35.2783 47.7076 3.28908472604838e-11 1.51814305127415 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00471|0|cel:CELE_M05D6.7|gbh-2; Protein GBH-2; K00471 gamma-butyrobetaine dioxygenase [EC:1.14.11.1] (A) Lysine degradation (ko00310) [I] Lipid transport and metabolism Taurine catabolism dioxygenase TauD, TfdA family Protein GBH-2 {ECO:0000313|EMBL:CAA91416.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein GBH-2 [Caenorhabditis elegans] F44A2.3 gene36057 1061 1209 1005 2584 2392 2501 35.3647391 40.564067361205 33.15555247 87.596562 81.836994 90.4618516185 2.91658940625364e-10 1.17716764210439 up -- -- Molecular Function: lipid binding (GO:0008289);; -- -- [V] Defense mechanisms LBP / BPI / CETP family, C-terminal domain Protein F44A2.3 {ECO:0000313|EMBL:CCD71193.1} OS=Caenorhabditis elegans PE=4 SV=5 S Function unknown Protein F44A2.3 [Caenorhabditis elegans] nhr-130 gene33003 152 158 131 299 287 364 7.28109 7.33644 6.12281 13.8583 14.0263 17.8088 2.70074631818045e-05 1.09356979026703 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) CRE-NHR-130 protein {ECO:0000313|EMBL:EFO99905.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 K Transcription Protein NHR-130 [Caenorhabditis elegans] T22F3.10 gene33999 52 59 52 212 207 185 2.704254 3.047061 2.70137611903 10.170574 10.450825 9.003905 8.89017334451404e-11 1.87569458979442 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein T22F3.10 {ECO:0000313|EMBL:CCD70905.2} OS=Caenorhabditis elegans PE=4 SV=5 G Carbohydrate transport and metabolism Protein T22F3.10 [Caenorhabditis elegans] nlp-18 gene8177 1540 1697 747 2547 2510 3096 243.778614514 273.42092 95.45440286626 289.8632 330.09432 343.284647332177 0.000882780318229755 1.02062243578133 up -- -- -- -- -- -- -- -- Protein NLP-18 {ECO:0000313|EMBL:CAB04255.2} OS=Caenorhabditis elegans PE=4 SV=2 C Energy production and conversion Protein NLP-18 [Caenorhabditis elegans] hrg-7 gene37635 428 547 381 1004 890 992 22.983050416 29.4654087 20.2884934057 54.2709351502 48.4126530097 56.4702289401 2.70732954339366e-07 1.07635218637517 up -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease;; Xylanase inhibitor N-terminal Protein ASP-10, isoform a {ECO:0000313|EMBL:CAA99777.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein ASP-10, isoform a [Caenorhabditis elegans] F14F9.2 gene34459 143 100 33 203 230 198 13.914 9.79813 3.3167 20.3517 22.3883 20.3774 0.00396103620375626 1.17989059687872 up -- -- -- -- -- -- -- -- Protein F14F9.2 {ECO:0000313|EMBL:CCD62730.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F14F9.2 [Caenorhabditis elegans] cyc-2.2 gene37593 80 119 147 60 36 46 35.6463 47.4835 62.9053 26.3575 19.4787 22.7239 0.00622642086771005 -1.29998435666845 down [C] Energy production and conversion Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: heme binding (GO:0020037);; K08738|1.57033e-85|cel:CELE_ZC116.2|cyc-2.2; Protein CYC-2.2; K08738 cytochrome c (A) Sulfur metabolism (ko00920) [C] Energy production and conversion Cytochrome c CBN-CYC-2.2 protein {ECO:0000313|EMBL:EGT45199.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 C Energy production and conversion Protein CYC-2.2 [Caenorhabditis elegans] C25G4.8 gene20179 22 27 33 8 11 8 1.32355 1.65753 1.98986 0.49272 0.692506 0.520715 0.00433692934902614 -1.61680922277073 down -- -- -- -- -- -- -- Protein of unknown function (DUF1265) Protein C25G4.8 {ECO:0000313|EMBL:CAA94574.2} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein C25G4.8 [Caenorhabditis elegans] ugt-43 gene19366 101 73 99 239 231 174 3.57458485 2.92011424911 3.904173 9.716266 9.9859994784 7.963959 1.76138388344395e-05 1.22283453138844 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-43, isoform b {ECO:0000313|EMBL:CBL43432.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein UGT-43, isoform b [Caenorhabditis elegans] dct-17 gene38001 2043 3130 1357 513 451 449 73.91365 113.01453 48.3354 18.54909 16.67222 17.24614 0.00205140771141248 -2.22079170175245 down -- -- -- -- -- -- -- CUB-like domain Protein DCT-17, isoform a {ECO:0000313|EMBL:CAB04275.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein DCT-17, isoform a [Caenorhabditis elegans] ech-1.1 gene38671 124 87 114 39 50 34 2.9167486929 2.117796 2.7044265163 0.95577896 1.24660368 0.903446 4.59586317158908e-05 -1.4166039942394 down [I] Lipid transport and metabolism Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyacyl-CoA dehydrogenase activity (GO:0003857);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: fatty acid metabolic process (GO:0006631);; Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K07515|0|cel:CELE_C29F3.1|ech-1; Protein ECH-1; K07515 enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] (A) Fatty acid elongation (ko00062);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; beta-Alanine metabolism (ko00410);; Propanoate metabolism (ko00640);; Butanoate metabolism (ko00650);; Biosynthesis of unsaturated fatty acids (ko01040);; Carbon metabolism (ko01200);; Fatty acid metabolism (ko01212) [I] Lipid transport and metabolism Enoyl-CoA hydratase/isomerase family;; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain;; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain;; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Protein ECH-1 {ECO:0000313|EMBL:CAB02799.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ECH-1 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_29 12 37 21 102 125 53 0.584977 1.75352 1.02261 4.95724 6.31315 2.84452 0.00720682553732076 1.98763515932318 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; FTH domain Protein FBXA-216 {ECO:0000313|EMBL:CAA21741.3} OS=Caenorhabditis elegans PE=4 SV=3 J Translation, ribosomal structure and biogenesis -- cyp-14A3 gene45302 53 138 133 9 6 12 2.21522 5.7859 5.45557 0.396225 0.266261 0.563352 9.61122553081055e-05 -3.59829521772872 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-14A3 {ECO:0000313|EMBL:CAA90617.1} OS=Caenorhabditis elegans PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-14A3 [Caenorhabditis elegans] dod-20 gene32983 143 200 146 353 362 466 4.5349276571 6.5802749311 4.687811 13.8981184643 12.9231415701 18.2042704 2.70732954339366e-07 1.25919970764303 up -- -- -- -- -- -- -- Transmembrane glycoprotein Protein DOD-20 {ECO:0000313|EMBL:CCD62232.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein DOD-20 [Caenorhabditis elegans] K08D9.4 gene33839 59 67 76 187 159 207 3.741114425 5.158163475 4.293922422 11.054419873 11.610893978 13.5618583352037 1.0689762412925e-06 1.43860275421537 up -- -- -- -- -- -- -- Alpha/beta hydrolase of unknown function (DUF1057);; Alpha/beta hydrolase family;; Alpha/beta hydrolase family Protein K08D9.4 {ECO:0000313|EMBL:CCD72795.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein K08D9.4 [Caenorhabditis elegans] F11A5.9 gene39080 976 803 1233 5469 6128 7029 39.4572 31.7705 49.0842 215.526 253.616 285.327 8.64851592076915e-35 2.61378467935356 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein F11A5.9 {ECO:0000313|EMBL:CAB07353.2} OS=Caenorhabditis elegans PE=4 SV=2 G Carbohydrate transport and metabolism Protein F11A5.9 [Caenorhabditis elegans] F32A5.4 gene6861 9485 9392 8362 17794 19056 21657 665.78165 613.683292 560.3369486881 1207.7585206782 1314.555757414 1538.93058 1.07075590717746e-08 1.08925990956483 up -- -- -- -- -- -- -- Pepsin inhibitor-3-like repeated domain Putative uncharacterized protein {ECO:0000313|EMBL:EFP07699.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein F32A5.4, isoform a [Caenorhabditis elegans] H11E01.2 gene41108 127 128 122 306 346 438 5.241650821 5.250677 4.9072186537 12.397689021 14.44020559 18.0686161877 1.56715559692176e-08 1.51813079633726 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein H11E01.2 {ECO:0000313|EMBL:CCD61776.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein H11E01.2 [Caenorhabditis elegans] pud-4 gene33542 399 376 613 23 15 28 87.4045810919 76.0703519233 130.01499 4.7999084103 3.70150010965 6.373868971 3.52501413364761e-14 -4.40961880420865 down -- -- -- -- -- -- -- -- Protein PUD-4, isoform a {ECO:0000313|EMBL:CCU83358.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms PUD-4, isoform a [Caenorhabditis elegans] F49C12.2 gene18867 19 48 17 166 147 159 1.28113 3.17891 1.15947 11.422769 10.482055 11.8655 1.06912518170187e-14 2.47896286642408 up -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein F49C12.2 {ECO:0000313|EMBL:CAA92507.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F49C12.2 [Caenorhabditis elegans] F49C12.5 gene18870 17 15 11 107 70 70 0.628684 0.536705 0.464289 3.72642600000007 2.531514 3.0579 3.11057991688192e-08 2.50747211405364 up -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein Y97E10B.1 {ECO:0000313|EMBL:CCD70068.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F49C12.5, isoform a [Caenorhabditis elegans] pcca-1 gene43377 7143 6660 7104 13424 14592 14683 149.302319658982 140.799535100005 151.0323519 280.26109758 299.522997 310.2680685047 6.36780559814713e-08 1.01604784448241 up [I] Lipid transport and metabolism Molecular Function: ATP binding (GO:0005524);; Molecular Function: D-alanine-D-alanine ligase activity (GO:0008716);; K01965|0|cel:CELE_F27D9.5|pcca-1; Protein PCCA-1; K01965 propionyl-CoA carboxylase alpha chain [EC:6.4.1.3] (A) Valine, leucine and isoleucine degradation (ko00280);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640) [IE] Lipid transport and metabolism;; Amino acid transport and metabolism Carbamoyl-phosphate synthase L chain, ATP binding domain;; Carbamoyl-phosphate synthase L chain, N-terminal domain;; Biotin carboxylase C-terminal domain;; Biotin-requiring enzyme;; ATP-grasp domain;; Biotin-lipoyl like;; D-ala D-ala ligase C-terminus;; ATP-grasp domain;; ATP-grasp domain;; RimK-like ATP-grasp domain CRE-PCCA-1 protein {ECO:0000313|EMBL:EFO82470.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 W Extracellular structures Protein PCCA-1 [Caenorhabditis elegans] F15A4.5 gene8676 246 258 154 563 532 653 10.5308404291 11.8062859544323 7.8241303198 16.868982325 16.1301525102 20.312931 5.43848692502368e-10 1.39645848155523 up -- -- -- -- -- -- -- -- Protein F15A4.5 {ECO:0000313|EMBL:CAB02943.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F15A4.5 [Caenorhabditis elegans] ZK783.6 gene11504 22 34 25 11 8 9 1.35287 1.9895 1.4634 0.641286 0.501384 0.533432 0.00658112729118484 -1.54617120355696 down -- -- -- -- -- -- -- -- Protein ZK783.6 {ECO:0000313|EMBL:CCD65253.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZK783.6 [Caenorhabditis elegans] T19H12.6 gene34362 128 110 123 61 50 64 3.72810945851 3.1578049761 3.5298947814 1.75058202 1.46359282783 1.923585058 0.00204164571796 -1.05923180450931 down [E] Amino acid transport and metabolism Biological Process: glutathione catabolic process (GO:0006751);; Molecular Function: glutathione hydrolase activity (GO:0036374);; -- -- [E] Amino acid transport and metabolism Gamma-glutamyltranspeptidase Protein T19H12.6 {ECO:0000313|EMBL:CCD67002.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein T19H12.6 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_632 69 103 45 168 215 219 2.33736 3.52025 1.48422 5.83572 7.41042 7.83897 6.29706743368048e-07 1.46029762516865 up -- -- Cellular Component: integral component of membrane (GO:0016021);; Biological Process: dsRNA transport (GO:0033227);; Molecular Function: RNA transmembrane transporter activity (GO:0051033);; -- -- -- -- dsRNA-gated channel SID-1 Protein Y37H2C.1 {ECO:0000313|EMBL:CAA19499.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones -- T25B9.1 gene19462 609 587 453 322 231 234 35.7659 34.2308 26.3769 18.9277 13.5518 13.928 3.21840323236881e-06 -1.08155672403237 down [H] Coenzyme transport and metabolism Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; K00639|0|cel:CELE_T25B9.1|T25B9.1; Protein T25B9.1; K00639 glycine C-acetyltransferase [EC:2.3.1.29] (A) Glycine, serine and threonine metabolism (ko00260) [E] Amino acid transport and metabolism Aminotransferase class I and II;; Aminotransferase class-V Protein T25B9.1 {ECO:0000313|EMBL:CAA94376.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein T25B9.1 [Caenorhabditis elegans] mpst-4 gene5864 48 78 70 22 16 24 3.49092 5.63856 5.04242 1.64881 1.25902 1.96346 4.57059677137831e-05 -1.67420073168593 down [P] Inorganic ion transport and metabolism -- -- -- [V] Defense mechanisms Rhodanese-like domain Protein MPST-6 {ECO:0000313|EMBL:CCD74088.1} OS=Caenorhabditis elegans PE=4 SV=1 V Defense mechanisms Protein MPST-5 [Caenorhabditis elegans] col-175 gene43981 1908 2139 2348 868 938 868 106.7772836 110.229580002962 129.72287 36.79901206773 45.5888150640002 36.6930357000752 8.57650872057793e-12 -1.27213535263077 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-175 {ECO:0000313|EMBL:CCD66768.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures COL-175 [Caenorhabditis elegans] nspe-6 gene8733 25 27 23 382 215 432 440.6917 451.455 391.9947 7559.537 6936.7 12132.91 8.03942898950342e-09 3.76417129954632 up -- -- -- -- -- -- -- Protein of unknown function (DUF1412) Protein NSPE-6 {ECO:0000313|EMBL:CAE17993.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein NSPE-6 [Caenorhabditis elegans] C34F11.8 gene6001 267 273 241 563 505 597 32.5572 32.3551 29.1013 68.3283 64.217 74.1693 3.00518295177371e-06 1.07820069248099 up -- -- -- -- -- -- -- -- Protein C34F11.8 {ECO:0000313|EMBL:CCD65827.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein C34F11.8 [Caenorhabditis elegans] gipc-1 gene10639 495 573 657 240 247 251 30.9377 35.9382 41.3955 15.1746 15.6714 16.5472 4.36200942069524e-08 -1.23915461404034 down -- -- -- -- -- [TU] Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport -- Protein GIPC-1 {ECO:0000313|EMBL:CCD66775.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein GIPC-1 [Caenorhabditis elegans] F09C6.14 gene39355 13 10 6 39 22 25 3.4728 44.585943 0.570672 18.29754 77.02646 2.53221 0.00552584185993895 1.55360366478759 up -- -- -- -- -- -- -- -- Protein F09C6.14 {ECO:0000313|EMBL:CAI79125.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein F09C6.14 [Caenorhabditis elegans] far-4 gene37756 10 8 2 53 37 41 1.30272 1.01665 0.345883 6.67889 5.00801 5.49837 6.89621693364974e-08 2.69817675677904 up -- -- Molecular Function: lipid binding (GO:0008289);; -- -- -- -- Nematode fatty acid retinoid binding protein (Gp-FAR-1) Protein FAR-4 {ECO:0000313|EMBL:CAB01421.1} OS=Caenorhabditis elegans PE=4 SV=1 TZ Signal transduction mechanisms;; Cytoskeleton Protein FAR-4 [Caenorhabditis elegans] vit-4 gene41779 1987 3061 5995 470 523 272 19.44332 29.5758 57.51428 4.565821 4.74957 2.586584 0.0081295162080864 -3.14177583667636 down -- -- Molecular Function: lipid transporter activity (GO:0005319);; Biological Process: lipid transport (GO:0006869);; -- -- [I] Lipid transport and metabolism Lipoprotein amino terminal region;; Domain of unknown function (DUF1943);; von Willebrand factor type D domain CRE-VIT-5 protein {ECO:0000313|EMBL:EFO82519.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 I Lipid transport and metabolism Protein VIT-4 [Caenorhabditis elegans] rol-1 gene8576 3038 3374 3644 1014 1305 1009 91.8957 95.0219 102.1901 27.81183 31.97914 24.80596 3.3394519771283e-19 -1.60934336156627 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein ROL-1 {ECO:0000313|EMBL:CAB55014.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ROL-1 [Caenorhabditis elegans] F23D12.11 gene45704 41 26 34 10 0 2 101.09 57.8966 82.9143 26.6527 0 7.16696 5.3938790033666e-08 -3.09258956463914 down -- -- -- -- -- -- -- -- Protein F23D12.11 {ECO:0000313|EMBL:CAZ65487.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F23D12.11 [Caenorhabditis elegans] F57F4.2 gene34904 1998 1294 310 3271 2759 3039 190.071 121.001 30.4191 311.339 267.94 294.31 0.00285644487204808 1.31882906894197 up -- -- -- -- -- -- -- -- Protein F57F4.2 {ECO:0000313|EMBL:CCD69471.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein F57F4.2 [Caenorhabditis elegans] ZK596.1 gene19521 481 529 327 1362 1201 1377 56.8210876903 57.830993 36.3122145693 157.0690350543 148.1856603031 170.786968 3.35091631407859e-15 1.54589319473036 up -- -- -- -- -- -- -- Domain of unknown function DUF148 Protein ZK596.1 {ECO:0000313|EMBL:CAA93430.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK596.1 [Caenorhabditis elegans] cpr-4 gene35001 6640 5799 6139 23497 23677 26105 393.197 330.858 353.019 1312.079 1316.564 1438.265 2.37632269455725e-26 1.96555612203663 up -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; K01363|0|cel:CELE_F44C4.3|cpr-4; Protein CPR-4; K01363 cathepsin B [EC:3.4.22.1] (A) Lysosome (ko04142) [O] Posttranslational modification, protein turnover, chaperones Papain family cysteine protease CBN-CPR-4 protein {ECO:0000313|EMBL:EGT47019.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 K Transcription Protein CPR-4 [Caenorhabditis elegans] oatr-1 gene11117 4526 4527 4798 2367 2205 2081 204.39648 200.94968 217.53844 106.79113 101.40207 97.133029 4.19374972135655e-09 -1.07239071081557 down [E] Amino acid transport and metabolism Molecular Function: transaminase activity (GO:0008483);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; K00819|0|cbr:CBG09115|Hypothetical protein CBG09115; K00819 ornithine--oxo-acid transaminase [EC:2.6.1.13] (A) Arginine and proline metabolism (ko00330) [E] Amino acid transport and metabolism Aminotransferase class-III Putative uncharacterized protein {ECO:0000313|EMBL:EFO83696.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 R General function prediction only Protein C16A3.10, isoform a [Caenorhabditis elegans] swt-6 gene38095 351 455 451 1244 1118 1165 39.27284 48.982118 49.096575 142.65207 139.93957 134.41362 1.42787672399222e-13 1.47435265019259 up -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [R] General function prediction only Sugar efflux transporter for intercellular exchange Sugar transporter SWEET {ECO:0000256|RuleBase:RU910715} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein SWT-6 [Caenorhabditis elegans] haly-1 gene44490 1671 1824 2035 853 857 787 43.7645 47.48106 51.94077 21.346121 22.09322609 20.32702579 1.04599960351123e-09 -1.1614774377137 down [E] Amino acid transport and metabolism -- K01745|0|cel:CELE_F47B10.2|haly-1; Protein HALY-1; K01745 histidine ammonia-lyase [EC:4.3.1.3] (A) Histidine metabolism (ko00340) [Q] Secondary metabolites biosynthesis, transport and catabolism Aromatic amino acid lyase Histidine ammonia-lyase {ECO:0000256|RuleBase:RU004479} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 S Function unknown Protein HALY-1 [Caenorhabditis elegans] C10C5.3 gene18897 26 36 59 151 145 127 1.42471043839 1.674575487 2.7633242 7.458464 6.38325 6.46626175762 2.33804728272561e-08 1.79038644495533 up [E] Amino acid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; K01436|0|cel:CELE_C10C5.3|C10C5.3; Protein C10C5.3; K01436 amidohydrolase [EC:3.5.1.-] (A) -- [E] Amino acid transport and metabolism Peptidase family M20/M25/M40;; Peptidase dimerisation domain Aminoacylase-1 {ECO:0000256|PIRNR:PIRNR036696} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein C10C5.3 [Caenorhabditis elegans] C33H5.1 gene18344 7 12 5 50 29 61 0.543828 0.905462 0.417431 3.81098 2.3203 5.05895 0.000164306752353611 2.53221816500253 up -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein C33H5.1 {ECO:0000313|EMBL:CCD66585.1} OS=Caenorhabditis elegans PE=4 SV=3 I Lipid transport and metabolism Protein C33H5.1 [Caenorhabditis elegans] W08G11.1 gene39149 73 65 81 32 46 28 3.956 3.57151 4.4469 1.81031 2.68923 1.71474 0.00890894973978522 -1.06132469599005 down -- -- -- -- -- -- -- Caenorhabditis protein of unknown function, DUF268 Protein W08G11.1 {ECO:0000313|EMBL:CAB07296.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein W08G11.1 [Caenorhabditis elegans] his-70 gene10348 28 37 48 8 11 13 10.7131 12.4937 17.1227 2.97518 5.11473 5.62238 0.000262651032119755 -1.83393141541566 down [B] Chromatin structure and dynamics Molecular Function: DNA binding (GO:0003677);; -- -- [B] Chromatin structure and dynamics Core histone H2A/H2B/H3/H4 Histone H3 {ECO:0000256|RuleBase:RU004471} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 L Replication, recombination and repair Protein HIS-70 [Caenorhabditis elegans] best-1 gene20383 170 212 180 2779 2563 2914 8.277 10.3784 8.70588 137.7943 131.4214 154.8103 6.5649867111006e-86 3.8631376733647 up -- -- -- -- -- [R] General function prediction only Bestrophin, RFP-TM, chloride channel Protein CBG01822 {ECO:0000313|EMBL:CAP22816.1} OS=Caenorhabditis briggsae PE=4 SV=1 S Function unknown Protein BEST-1 [Caenorhabditis elegans] F23A7.8 gene46327 56 39 61 30 13 19 1114.07 849.242 1408.1 731.509 600.839 661.684 0.00268882333838895 -1.34772778769568 down -- -- -- -- -- -- -- -- Protein F23A7.8 {ECO:0000313|EMBL:CAJ34989.1} OS=Caenorhabditis elegans PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein F23A7.8 [Caenorhabditis elegans] fbxa-6 gene9382 142 125 68 232 247 256 9.05291 7.77321 4.064722 12.76264 14.62721 16.11086 5.23406319677631e-05 1.12042791500252 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-6 {ECO:0000313|EMBL:CCD68268.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein FBXA-6 [Caenorhabditis elegans] Y6G8.2 gene39660 409 439 366 789 1044 963 7.617842 7.99376600013908 6.534249 15.311705 19.3267 17.24017 1.17802086251397e-08 1.19027956906439 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein Y6G8.2, isoform a {ECO:0000313|EMBL:CBA11620.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y6G8.2, isoform a [Caenorhabditis elegans] B0252.1 gene6754 77 103 67 188 223 138 2.17241 2.9824 1.9076 5.56867 6.68391 4.43043 0.00176110011443134 1.13907638873934 up [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain Protein B0252.1 {ECO:0000313|EMBL:CCD61536.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein B0252.1 [Caenorhabditis elegans] col-49 gene616 1643 1835 1952 481 613 472 105.636 110.837 123.115 29.5198 37.1688 28.2704 7.71936944705015e-22 -1.8078695109539 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-49 {ECO:0000313|EMBL:CCD67358.1} OS=Caenorhabditis elegans PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein COL-49 [Caenorhabditis elegans] rhr-1 gene34544 5254 6354 5743 1538 1424 1395 230.5014 273.9213 244.05127 67.51751 61.24401 61.95605 6.65757842210769e-30 -2.00759255851405 down [P] Inorganic ion transport and metabolism Molecular Function: ammonium transmembrane transporter activity (GO:0008519);; Biological Process: ammonium transport (GO:0015696);; Cellular Component: membrane (GO:0016020);; K06580|0|cel:CELE_F08F3.3|rhr-1; Protein RHR-1; K06580 ammonium transporter Rh (A) -- [UR] Intracellular trafficking, secretion, and vesicular transport;; General function prediction only Ammonium Transporter Family Protein RHR-1 {ECO:0000313|EMBL:CCD65593.1} OS=Caenorhabditis elegans PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein RHR-1 [Caenorhabditis elegans] F25F2.1 gene10494 65 102 85 42 43 38 2.054532 3.17582 2.658284 1.369549 1.38113 1.2947 0.00670479568584339 -1.04826999926859 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein kinase domain Protein F25F2.1, isoform b {ECO:0000313|EMBL:CAD91629.2} OS=Caenorhabditis elegans PE=4 SV=2 W Extracellular structures Protein F25F2.1, isoform b [Caenorhabditis elegans] C54F6.12 gene35381 11 12 9 52 37 58 1.99209 2.01883 1.55606 9.09894 7.39528 11.116 2.38720267384215e-06 2.18600222996006 up -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein C54F6.12 {ECO:0000313|EMBL:CCD62991.1} OS=Caenorhabditis elegans PE=4 SV=2 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein C54F6.12 [Caenorhabditis elegans] Y41D4B.26 gene13607 57 52 90 28 26 29 8.80432 7.48753 13.0569 4.30242 4.35096 4.75872 0.00905051487670173 -1.27691165080442 down -- -- -- -- -- [T] Signal transduction mechanisms -- Protein Y41D4B.26 {ECO:0000313|EMBL:CCD66724.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein Y41D4B.26 [Caenorhabditis elegans] F48D6.4 gene42030 1638 1603 1601 3716 3536 4238 570.36416151 541.53303464 543.234901413 1248.8461485 1784.54400524997 2224.805282108 1.02219852347027e-11 1.23264256091373 up -- -- -- -- -- -- -- -- Protein F48D6.4, isoform a {ECO:0000313|EMBL:CCD67848.1} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein F48D6.4, isoform a [Caenorhabditis elegans] clec-230 gene38666 42 52 31 14 7 3 9.88674 11.433 7.07648 3.26566 1.95074 0.751583 1.94450869119743e-06 -2.39611730188906 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-230 {ECO:0000313|EMBL:CAB02798.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CLEC-230 [Caenorhabditis elegans] ZC196.3 gene35818 20 15 17 34 37 56 1.094711745481 0.85982969562 0.91850942497 2.04626572312 2.24324411716 3.59101388373 0.00874293151619756 1.27427524674414 up -- -- -- -- -- -- -- Protein of unknown function (DUF713) Protein ZC196.3 {ECO:0000313|EMBL:CCD62094.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZC196.3 [Caenorhabditis elegans] ugt-20 gene16963 490 732 683 1519 1487 1366 20.3067 31.0918 28.3477 66.0785 64.9667 63.6091 1.41438641649733e-09 1.18466442170254 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain;; Glycosyl transferase family 1 Protein UGT-20 {ECO:0000313|EMBL:CCD72379.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein UGT-20 [Caenorhabditis elegans] pals-7 gene3699 14 7 3 54 39 50 0.4175609117049 0.4720539441815 0.10669287951 1.72325535963479 1.78578908461809 2.00718629617916 8.96057888451386e-08 2.5606198214969 up -- -- -- -- -- -- -- -- Protein C17H1.8, isoform b {ECO:0000313|EMBL:CDX47428.1} OS=Caenorhabditis elegans PE=4 SV=1 -- -- C17H1.8, isoform b [Caenorhabditis elegans] Y40C5A.4 gene18162 219 202 151 375 445 385 13.52351 13.00205 9.4833995 23.93449 28.38475 25.57765 1.78721566372364e-05 1.06139508350896 up -- -- -- -- -- -- -- -- Protein Y40C5A.4, isoform b {ECO:0000313|EMBL:CCD71162.2} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Y40C5A.4, isoform b [Caenorhabditis elegans] daao-1 gene13795 86 93 79 302 261 267 3.705345 3.490765 3.261709 15.230609 10.986472 12.664 2.56541104005553e-10 1.6716883114393 up [E] Amino acid transport and metabolism Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00273|0|cel:CELE_Y69A2AR.5|daao-1; Protein DAAO-1; K00273 D-amino-acid oxidase [EC:1.4.3.3] (A) Glycine, serine and threonine metabolism (ko00260);; Arginine and proline metabolism (ko00330);; D-Arginine and D-ornithine metabolism (ko00472);; Peroxisome (ko04146) [E] Amino acid transport and metabolism FAD dependent oxidoreductase Putative uncharacterized protein {ECO:0000313|EMBL:EGT48636.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein DAAO-1 [Caenorhabditis elegans] F42G8.8 gene18451 66 85 83 29 25 43 3.94141 4.91959 4.79226 1.74401 1.52719 2.60344 0.000998214520877758 -1.28398019479022 down [T] Signal transduction mechanisms Molecular Function: hydrolase activity (GO:0016787);; K01090|0|cel:CELE_F42G8.8|F42G8.8; Protein F42G8.8; K01090 protein phosphatase [EC:3.1.3.16] (A) -- [TR] Signal transduction mechanisms;; General function prediction only Calcineurin-like phosphoesterase Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273} OS=Caenorhabditis elegans PE=3 SV=2 T Signal transduction mechanisms F42G8.8 [Caenorhabditis elegans] F57C2.4 gene9208 115 125 135 81 43 47 425.826 424.791 502.405 321.949 302.271 252.795 0.000650376163182411 -1.14837412806567 down -- -- -- -- -- -- -- -- Protein F57C2.4 {ECO:0000313|EMBL:CAB05526.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F57C2.4 [Caenorhabditis elegans] asp-14 gene42880 43236 50182 28739 12723 11477 9875 2113.462321886 2349.899239478 1300.241663 531.805703578 481.02514732 370.460397744 7.71876522016601e-06 -1.85534771824722 down -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease Protein ASP-14 {ECO:0000313|EMBL:CCD72625.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ASP-14 [Caenorhabditis elegans] nstp-7 gene33044 25 22 27 14 1 4 1.90494 1.64926 2.02004 1.07322 0.102594 0.332411 0.000885024376905513 -1.97968153615434 down [GER] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only Cellular Component: Golgi membrane (GO:0000139);; Molecular Function: sugar:proton symporter activity (GO:0005351);; Biological Process: carbohydrate transport (GO:0008643);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [G] Carbohydrate transport and metabolism Nucleotide-sugar transporter;; Multidrug resistance efflux transporter;; EamA-like transporter family;; Triose-phosphate Transporter family Protein NSTP-7 {ECO:0000313|EMBL:CCD64474.2} OS=Caenorhabditis elegans PE=4 SV=2 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein NSTP-7 [Caenorhabditis elegans] sulp-2 gene42509 381 438 336 1023 939 949 11.366372 13.58753 10.511052333 31.980970235942 30.02863321564 31.7233400020739 1.55897552590538e-10 1.31992675898287 up [P] Inorganic ion transport and metabolism Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [P] Inorganic ion transport and metabolism Sulfate transporter family;; Sulfate transporter N-terminal domain with GLY motif;; STAS domain Protein SULP-2 {ECO:0000313|EMBL:CCD83471.1} OS=Caenorhabditis elegans PE=2 SV=1 T Signal transduction mechanisms Protein SULP-2 [Caenorhabditis elegans] col-138 gene32562 1317 1293 1575 518 633 551 88.5687 83.9342 102.692 32.8299 41.1454 35.3239 1.84110993694171e-11 -1.31231693006066 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-138 {ECO:0000313|EMBL:CAM36330.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein COL-138 [Caenorhabditis elegans] C50F7.5 gene18305 1226 1189 988 7066 8038 8628 81.4288 69.7419 59.7792 431.055 471.967 509.347 2.53649692438043e-54 2.78842982049598 up -- -- -- -- -- -- -- -- Protein C50F7.5 {ECO:0000313|EMBL:CCD67453.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown hypothetical protein C50F7.7 - Caenorhabditis elegans C36C5.12 gene33825 74 72 42 19 7 8 11.6472 11.0361 6.51181 3.05115 1.26805 1.34798 4.77993204970597e-06 -2.48239146396082 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein T28A11.3 {ECO:0000313|EMBL:CCD70562.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C36C5.12 [Caenorhabditis elegans] Y38E10A.9 gene8730 3 0 1 59 44 46 33.6304 0 20.4234 727.842 963.515 817.007 7.14945632752859e-17 5.20119917370729 up -- -- -- -- -- -- -- Protein of unknown function (DUF1412) Protein Y38E10A.9 {ECO:0000313|EMBL:CAB54400.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y38E10A.9 [Caenorhabditis elegans] clec-7 gene35281 343 347 362 943 842 929 19.8754 19.68508 20.51394 53.7498 51.8281 55.2795 8.24823515169136e-11 1.35294310170277 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain;; UL45 protein Protein CLEC-7 {ECO:0000313|EMBL:CCD62811.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-7 [Caenorhabditis elegans] F41E6.7 gene35770 64 50 41 152 92 120 5.15821 3.75124484462 3.188052 13.76087 8.90685 9.756556 0.00152377073260429 1.21690459717857 up -- -- -- -- -- -- -- -- Protein F41E6.7 {ECO:0000313|EMBL:CCD64099.1} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein F41E6.7 [Caenorhabditis elegans] vit-2 gene42324 32319 30497 44320 86298 98841 75949 281.67807 258.67898 377.02247 727.0865 764.0439 609.2206 1.36770368128682e-08 1.27014584905974 up -- -- Molecular Function: lipid transporter activity (GO:0005319);; Biological Process: lipid transport (GO:0006869);; -- -- [I] Lipid transport and metabolism Lipoprotein amino terminal region;; Domain of unknown function (DUF1943);; von Willebrand factor type D domain Protein VIT-2, isoform b {ECO:0000313|EMBL:CCD65571.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein VIT-2, isoform a [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_576 24 35 43 6 16 13 1.15273 1.61478 1.97697 0.288792 0.815531 0.673859 0.00293993923596196 -1.55608527326892 down -- -- -- -- -- -- -- F-box associated Protein F29G9.7 {ECO:0000313|EMBL:CCD64138.1} OS=Caenorhabditis elegans PE=4 SV=3 O Posttranslational modification, protein turnover, chaperones -- ZK896.4 gene20293 258 214 217 116 113 74 12.618775 10.12871 10.17143 5.68402 5.560791 3.78658 1.76818385318484e-05 -1.20002092527953 down -- -- -- -- -- -- -- CUB-like domain Protein ZK896.4 {ECO:0000313|EMBL:CAB05319.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein ZK896.4 [Caenorhabditis elegans] cyp-36A1 gene2102 477 523 726 1343 1369 1581 22.0846 24.4888 33.6757 64.5999 67.6744 81.0698 2.59440889316432e-11 1.29999379479773 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17958|0|cel:CELE_C34B7.3|cyp-36A1; Protein CYP-36A1; K17958 cytochrome P450, family 36, subfamily A (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 CRE-CYP-36A1 protein {ECO:0000313|EMBL:EFO84710.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-36A1 [Caenorhabditis elegans] ugt-51 gene34471 262 216 249 792 971 1009 8.66015700016628 6.21228271080702 8.57474441001542 21.5203624 23.4730617110949 28.077788 2.39754327348446e-20 1.91675456934564 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-51 {ECO:0000313|EMBL:CCD83358.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein UGT-51 [Caenorhabditis elegans] ZK1025.3 gene3158 165 228 99 15 17 18 9.25135 13.213549 5.823307 0.807354 0.979861 1.17600000002187 1.59121229204427e-05 -3.3107082613901 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein ZK1025.3 {ECO:0000313|EMBL:CAA18370.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein ZK1025.3 [Caenorhabditis elegans] Y73F4A.1 gene18776 112 153 167 426 322 352 19.8325 25.0578 27.7887 74.5532 62.282 67.1799 7.40986040968482e-08 1.33382325699538 up -- -- -- -- -- -- -- DOMON domain Putative uncharacterized protein {ECO:0000313|EMBL:EFP07937.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only Protein Y73F4A.1 [Caenorhabditis elegans] F07C4.12 gene35427 80 55 61 383 428 391 3.71320961 2.5514626532504 2.840963263 17.1941120000519 20.37714 17.81673298 4.38488525840138e-25 2.60198144829559 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein F07C4.12, isoform b {ECO:0000313|EMBL:CCD64302.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein F07C4.12, isoform b [Caenorhabditis elegans] AC7.3 gene15003 36 46 33 8 20 13 4.1833 5.3127 3.94163 0.9731 2.44767 1.66955 0.00259720693925454 -1.50008969444999 down -- -- -- -- -- -- -- -- Protein AC7.3 {ECO:0000313|EMBL:CCD61153.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein AC7.3 [Caenorhabditis elegans] pho-6 gene35695 194 149 114 369 345 484 8.092905 6.615836 4.714991 16.1105594 12.6855300000789 19.847002 5.23041574519302e-06 1.37666903319193 up -- -- Molecular Function: acid phosphatase activity (GO:0003993);; -- -- [I] Lipid transport and metabolism Histidine phosphatase superfamily (branch 2);; Histidine phosphatase superfamily (branch 1) Protein PHO-6 {ECO:0000313|EMBL:CCD70810.2} OS=Caenorhabditis elegans PE=4 SV=2 C Energy production and conversion Protein PHO-6 [Caenorhabditis elegans] Y45F10D.6 gene21104 61 55 80 28 15 18 9.90335 8.43041 12.5949 4.50773 2.58638 3.04446 3.59364252925772e-05 -1.70002523329017 down -- -- -- -- -- -- -- -- Protein Y45F10D.6 {ECO:0000313|EMBL:CAA16381.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein Y45F10D.6 [Caenorhabditis elegans] nspe-4 gene8732 87 79 55 618 509 723 310.34571 314.61369 191.79354 3608.8769 4575.9196 6083.5018 1.16025757534453e-23 3.05181837388936 up -- -- -- -- -- -- -- Protein of unknown function (DUF1412) Protein NSPE-4 {ECO:0000313|EMBL:CAB54402.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein NSPE-4 [Caenorhabditis elegans] srp-2 gene33118 387 418 548 217 185 248 21.8579206156 23.6875099453 31.196427081 12.57998842 10.767816838 14.9412181478 0.000108015627500658 -1.07226296325821 down [O] Posttranslational modification, protein turnover, chaperones -- -- -- [V] Defense mechanisms Serpin (serine protease inhibitor) Protein SRP-2 {ECO:0000313|EMBL:CCD63233.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein SRP-2 [Caenorhabditis elegans] ZK484.7 gene1400 64 64 77 29 24 37 3.86641 3.8137 4.7087 1.7656 1.45868 2.25843 0.00341617446146721 -1.20198726702564 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain Protein ZK484.7 {ECO:0000313|EMBL:CCD65804.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZK484.7 [Caenorhabditis elegans] ttr-44 gene37927 1904 1830 1016 3140 2811 4062 287.422505763 259.663406 145.683487615815 444.724728738796 438.484633 610.463100003868 0.00200148071064957 1.06287908517996 up -- -- Cellular Component: extracellular space (GO:0005615);; -- -- -- -- Transthyretin-like family Protein TTR-44, isoform a {ECO:0000313|EMBL:CAB01136.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein TTR-44, isoform a [Caenorhabditis elegans] K08D8.5 gene20306 534 563 524 1502 1427 1473 37.8233 38.8202 36.1057 105.282 102.473 106.334 1.68153080297267e-13 1.42723073705987 up -- -- -- -- -- -- -- CUB-like domain Protein K08D8.5 {ECO:0000313|EMBL:CAA97432.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein K08D8.5 [Caenorhabditis elegans] D2062.5 gene5083 32 30 40 8 8 17 10.87782188784 15.18358679 12.661803 3.674044919 3.217221 3.264566265 0.00160514704400065 -1.64187513983595 down -- -- -- -- -- -- -- -- Protein D2062.5 {ECO:0000313|EMBL:CCD68439.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein D2062.5 [Caenorhabditis elegans] bca-1 gene42778 763 789 698 1725 1838 2077 61.5744769301 56.5060164783 51.7441959022 112.7909212292 104.3514718385 111.510421002503 3.62386736597964e-12 1.31213022588548 up [P] Inorganic ion transport and metabolism Molecular Function: carbonate dehydratase activity (GO:0004089);; Molecular Function: zinc ion binding (GO:0008270);; -- -- [P] Inorganic ion transport and metabolism Carbonic anhydrase CBN-BCA-1 protein {ECO:0000313|EMBL:EGT43056.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 K Transcription Protein BCA-1 [Caenorhabditis elegans] cyp-32B1 gene33493 298 277 245 812 880 975 11.6941 10.8033 9.63786 31.7391 34.82 39.1165 4.99388618897879e-16 1.68779209425895 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17954|0|cel:CELE_Y5H2B.5|cyp-32B1; Protein CYP-32B1; K17954 cytochrome P450, family 32 (A) -- [QI] Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism Cytochrome P450 Protein CYP-32B1 {ECO:0000313|EMBL:CCD67436.1} OS=Caenorhabditis elegans PE=3 SV=2 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-32B1 [Caenorhabditis elegans] comt-4 gene33442 13 7 8 52 49 55 1.7317 0.937211 1.05902 6.54055 6.71029 7.46481 9.02739323028878e-08 2.46317454967547 up [R] General function prediction only Molecular Function: O-methyltransferase activity (GO:0008171);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism O-methyltransferase;; Methyltransferase domain Protein COMT-4 {ECO:0000313|EMBL:CCD70634.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein COMT-4 [Caenorhabditis elegans] T21F4.1 gene42517 1797 1703 2022 331 283 287 79.6173 75.623 90.5352 14.01003 12.28127 11.92132 2.64332644603227e-42 -2.63042138631875 down [E] Amino acid transport and metabolism Molecular Function: metal ion binding (GO:0046872);; -- -- [E] Amino acid transport and metabolism Arginase family Protein T21F4.1, isoform b {ECO:0000313|EMBL:CCD69509.1} OS=Caenorhabditis elegans PE=4 SV=1 E Amino acid transport and metabolism Protein T21F4.1, isoform b [Caenorhabditis elegans] cld-9 gene38008 1023 1289 964 501 405 454 47.6023691522 59.110339976 43.3310409 23.357531216 19.06930690292 21.75265170812 1.23836625871619e-09 -1.28202011051224 down -- -- -- -- -- -- -- CUB-like domain Protein F35E12.8, isoform a {ECO:0000313|EMBL:CAB04278.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F35E12.8, isoform a [Caenorhabditis elegans] C07G3.10 gene33951 46 46 30 103 122 116 5.00213 4.85162 3.27278 10.8803 14.0469 12.5099 1.8649892189418e-05 1.46974610312843 up -- -- Molecular Function: lipid binding (GO:0008289);; -- -- -- -- Nematode fatty acid retinoid binding protein (Gp-FAR-1) Protein C07G3.10 {ECO:0000313|EMBL:CCD62493.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C07G3.10 [Caenorhabditis elegans] clec-174 gene14165 80 141 76 244 421 354 3.00767 4.90492 2.66823 8.72702 14.4322 12.3421 8.98611078552895e-05 1.76701282625236 up -- -- -- -- -- -- -- Lectin C-type domain Protein CLEC-174 {ECO:0000313|EMBL:CCD71964.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-174 [Caenorhabditis elegans] cln-3.1 gene36915 119 154 108 74 53 50 7.36254483816 9.0027777748 6.63470607080534 4.683725726 3.420047566 3.34426422922972 0.0008395109832233 -1.1200473877928 down -- -- Cellular Component: membrane (GO:0016020);; K12389|0|cbr:CBG23153|Cbr-cln-3.1; C. briggsae CBR-CLN-3.1 protein; K12389 battenin (A) Lysosome (ko04142) [R] General function prediction only CLN3 protein Battenin {ECO:0000256|RuleBase:RU361113} OS=Caenorhabditis elegans PE=2 SV=1 T Signal transduction mechanisms Protein CLN-3.1, isoform a [Caenorhabditis elegans] ech-7 gene4030 403 474 587 1399 1000 1093 37.1568 41.9287 53.3101 124.545 91.4355 98.0616 2.52584045940397e-06 1.239073785119 up [I] Lipid transport and metabolism Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; -- -- [I] Lipid transport and metabolism Enoyl-CoA hydratase/isomerase family Protein ECH-7 {ECO:0000313|EMBL:CAC48118.1} OS=Caenorhabditis elegans PE=3 SV=1 P Inorganic ion transport and metabolism Protein ECH-7 [Caenorhabditis elegans] C39E9.8 gene20369 3091 3410 3416 8199 6947 8750 183.932006000068 190.715348 199.167914 463.054851 391.10744172746 508.834680003549 3.82040626323211e-12 1.25465480840445 up -- -- -- -- -- -- -- -- Protein C39E9.8, isoform a {ECO:0000313|EMBL:CAA94333.2} OS=Caenorhabditis elegans PE=4 SV=2 Z Cytoskeleton Protein C39E9.8, isoform a [Caenorhabditis elegans] col-88 gene9389 384 462 696 200 235 190 23.0306 26.7456 40.6416 11.2153 13.2452 10.3318 0.00759998209268664 -1.31768474653239 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-88 {ECO:0000313|EMBL:CCD71750.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-88 [Caenorhabditis elegans] C35A5.4 gene36524 41 42 56 10 29 16 1.55296 1.51942 2.09394 0.384394 1.12785 0.664769 0.00378552293122258 -1.35105411504567 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis elegans PE=4 SV=2 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein C35A5.4 [Caenorhabditis elegans] Y53F4B.23 gene9338 122 161 129 350 292 287 16.1781760735 20.7153895872 16.9436035397 46.741695659268 40.91195787308 36.9427747719 8.37376564289802e-06 1.15916175706412 up -- -- -- -- -- -- -- -- Protein Y53F4B.23 {ECO:0000313|EMBL:CAB70111.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Y53F4B.23 [Caenorhabditis elegans] C14C6.3 gene33031 73 85 93 37 31 29 4.62711 4.681405 5.56937 2.40261 1.909415 1.836601 0.00026507196787805 -1.38628914251602 down -- -- Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: galactoside 2-alpha-L-fucosyltransferase activity (GO:0008107);; Cellular Component: membrane (GO:0016020);; -- -- -- -- Glycosyl transferase family 11 Protein C14C6.3 {ECO:0000313|EMBL:CCD64460.1} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein C14C6.3 [Caenorhabditis elegans] srd-39 gene45319 4 3 0 172 218 236 0.2860745 0.2456162361 0 12.78639 17.13941 17.97373 3.42225398768981e-49 6.47112145753961 up -- -- -- K08473|0|cel:CELE_R04D3.8|srd-39; Protein SRD-39; K08473 nematode chemoreceptor (A) -- -- -- Serpentine type 7TM GPCR chemoreceptor Srd;; Serpentine type 7TM GPCR chemoreceptor Str Protein SRD-39 {ECO:0000313|EMBL:CAA94166.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein SRD-39 [Caenorhabditis elegans] T27E4.1 gene35976 89 100 77 203 221 234 4.86142 5.08922 4.45704 10.985 12.2802 14.17408 4.59429933788801e-06 1.2933231186764 up -- -- -- -- -- -- -- -- Protein T27E4.1 {ECO:0000313|EMBL:CCD65661.1} OS=Caenorhabditis elegans PE=4 SV=2 W Extracellular structures Protein T27E4.1 [Caenorhabditis elegans] Y45F10C.1 gene20689 44 41 45 18 16 17 1.39146 1.33536 1.45689 0.612302 0.556858 0.632608 0.00433692934902614 -1.36449913642636 down -- -- -- -- -- -- -- Domain of unknown function (DUF545) Protein Y45F10C.1 {ECO:0000313|EMBL:CAB16477.1} OS=Caenorhabditis elegans PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein Y45F10C.1 [Caenorhabditis elegans] C34D4.10 gene18040 113 117 154 69 48 43 7.19257 7.48057 9.80479 4.55739 3.24867 3.01064 0.000113856646409464 -1.27859712421207 down -- -- -- -- -- -- -- -- Protein C34D4.10 {ECO:0000313|EMBL:CCD66604.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein C34D4.10 [Caenorhabditis elegans] sqrd-1 gene22349 2812 2655 2664 8163 9232 10022 120.667192011229 115.547784 112.850553598174 352.0120009111 403.6050594 456.266690476519 1.34719902336415e-22 1.73968020317553 up [R] General function prediction only Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K17218|0|cel:CELE_F02H6.5|sqrd-1; Protein SQRD-1, isoform A; K17218 sulfide:quinone oxidoreductase [EC:1.8.5.-] (A) Sulfur metabolism (ko00920) [C] Energy production and conversion Pyridine nucleotide-disulphide oxidoreductase Protein SQRD-1, isoform a {ECO:0000313|EMBL:CAB05173.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein SQRD-1, isoform a [Caenorhabditis elegans] Y47D7A.15 gene34263 5101 4876 4619 1467 1494 1321 185.7724155447 185.2473144592 182.7994111119 54.217213518 54.91210997947 51.43289568081 6.91801888245717e-24 -1.78341309551824 down -- -- -- -- -- -- -- -- Protein Y47D7A.15 {ECO:0000313|EMBL:CCD69384.2} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein Y47D7A.15 [Caenorhabditis elegans] F23F12.12 gene11156 48 64 78 213 175 280 244.209 301.243 392.686 1187.26 1645.74 2145.7 3.17734533798001e-06 1.79967214859774 up -- -- -- -- -- -- -- -- Protein F23F12.12 {ECO:0000313|EMBL:CCD69931.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F23F12.12 [Caenorhabditis elegans] F23A7.4 gene46326 77 80 78 50 15 26 1342.15 1512.03 1588.43 1053.32 572.601 789.535 0.000372948035731041 -1.38466699414518 down -- -- -- -- -- -- -- -- Protein F23A7.4 {ECO:0000313|EMBL:CAB02978.1} OS=Caenorhabditis elegans PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein F23A7.4 [Caenorhabditis elegans] gba-2 gene4952 301 346 302 877 741 862 25.60717 23.61782 27.830326 42.9003 34.53537 40.57725 8.47290829954078e-11 1.37192140763105 up [M] Cell wall/membrane/envelope biogenesis -- K01201|0|cel:CELE_C33C12.8|gba-2; Protein GBA-2; K01201 glucosylceramidase [EC:3.2.1.45] (A) Other glycan degradation (ko00511);; Sphingolipid metabolism (ko00600);; Lysosome (ko04142) [G] Carbohydrate transport and metabolism O-Glycosyl hydrolase family 30 Glucosylceramidase {ECO:0000256|RuleBase:RU361188} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 G Carbohydrate transport and metabolism Protein GBA-2 [Caenorhabditis elegans] F39G3.2 gene34318 82 95 97 36 54 41 3.68726 4.2361 4.30581 1.63977 2.59709 2.00264 0.00404872548780268 -1.07821733385611 down -- -- -- -- -- -- -- Glycosyltransferase family 92 Protein F39G3.2 {ECO:0000313|EMBL:CCD65241.1} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein F39G3.2 [Caenorhabditis elegans] C18E9.8 gene7490 116 113 134 47 58 60 4.1184 4.09242 4.81796 1.72258 2.15946 2.37575 0.000701723658981062 -1.15157758955487 down -- -- -- -- -- -- -- -- Protein C18E9.8 {ECO:0000313|EMBL:CAA93857.1} OS=Caenorhabditis elegans PE=1 SV=1 T Signal transduction mechanisms Protein C18E9.8 [Caenorhabditis elegans] Y51H7C.13 gene4674 1220 1472 1608 475 684 426 43.09954416 45.4695777800003 49.6134142 13.83236 17.5894036537 9.957000986699 2.61172064017385e-10 -1.4538202438909 down -- -- -- -- -- -- -- -- Protein Y51H7C.13 {ECO:0000313|EMBL:CCD71799.1} OS=Caenorhabditis elegans PE=4 SV=2 A RNA processing and modification Protein Y51H7C.13 [Caenorhabditis elegans] cdr-1 gene38933 217 301 184 101 68 54 24.1938 32.5466 20.0749 11.4618 8.20645 6.73118 7.00121682392739e-05 -1.66843180685154 down -- -- -- -- -- [T] Signal transduction mechanisms Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain Protein CDR-1 {ECO:0000313|EMBL:CAB04302.1} OS=Caenorhabditis elegans PE=2 SV=1 R General function prediction only Protein CDR-1 [Caenorhabditis elegans] snf-7 gene13018 35 46 30 18 7 12 1.12749 1.49655 0.997379 0.594189 0.261058 0.428307 0.00151374052063199 -1.59935923728817 down -- -- Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [T] Signal transduction mechanisms Sodium:neurotransmitter symporter family Transporter {ECO:0000256|RuleBase:RU003732} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein SNF-7 [Caenorhabditis elegans] clec-3 gene5236 4265 4135 2148 1118 843 768 198.3367 182.2815 97.9465 49.2924 38.4104 34.0451 0.000483723078382481 -1.96433241676584 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain Protein CLEC-3 {ECO:0000313|EMBL:CCD62000.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein CLEC-3 [Caenorhabditis elegans] msp-38 gene19247 71 115 112 56 39 52 35.2085 51.1766 52.6619 26.5082 21.8763 27.0573 0.00575468270681322 -1.03362015424141 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein MSP-38 [Caenorhabditis elegans] T07G12.3 gene19386 53 67 63 19 20 26 1.832831 2.3400103307 2.201364 0.70114 0.744986 1.047458 0.000353963142560843 -1.50677680429058 down -- -- -- -- -- -- -- Protein of unknown function (DUF229) Protein T07G12.3 {ECO:0000313|EMBL:CAB05275.2} OS=Caenorhabditis elegans PE=4 SV=2 F Nucleotide transport and metabolism Protein T07G12.3 [Caenorhabditis elegans] tyr-2 gene13194 3225 3228 3530 7474 8623 8392 69.48094 67.82339 73.6333139 153.533987289 180.026168 173.450686654 1.30529774260043e-12 1.28050292472758 up -- -- Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; -- -- -- -- Common central domain of tyrosinase;; ShK domain-like Protein TYR-2 {ECO:0000313|EMBL:CAB04594.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein TYR-2 [Caenorhabditis elegans] cyp-13A4 gene7785 484 1064 827 3317 3770 2925 18.56285161 41.005047482 31.902613 131.12277 151.5992 121.124832 1.98967606120155e-19 2.06272098796812 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17861|0|cel:CELE_T10B9.1|cyp-13A4; Protein CYP-13A4; K17861 cytochrome P450, family 13 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Putative uncharacterized protein {ECO:0000313|EMBL:EGT38206.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-13A4 [Caenorhabditis elegans] acer-1 gene6740 4332 3865 5542 22080 23526 23524 194.974 174.306 249.78 1002.9 1052.12 1099.87 2.57163903842388e-36 2.31622165800988 up [C] Energy production and conversion Molecular Function: catalytic activity (GO:0003824);; Biological Process: acetyl-CoA metabolic process (GO:0006084);; -- -- [C] Energy production and conversion Acetyl-CoA hydrolase/transferase C-terminal domain;; Acetyl-CoA hydrolase/transferase N-terminal domain Protein C44B7.10 {ECO:0000313|EMBL:CCD61564.1} OS=Caenorhabditis elegans PE=1 SV=3 T Signal transduction mechanisms Protein C44B7.10 [Caenorhabditis elegans] clec-61 gene8010 366 248 226 1061 913 1232 19.381 13.0753 11.84 56.4418 49.6937 68.8626 4.70838516927497e-15 1.91802059114609 up -- -- -- -- -- -- -- von Willebrand factor type A domain;; von Willebrand factor type A domain Protein CLEC-61 {ECO:0000313|EMBL:CAA88986.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein CLEC-61 [Caenorhabditis elegans] nas-33 gene42884 271 252 172 114 121 93 8.68617996 8.069399 5.57253591825706 3.5037286987 3.909039 3.1640516 0.000758755364554784 -1.09705204819364 down -- -- Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; K08076|0|cel:CELE_K04E7.3|nas-33; Protein NAS-33; K08076 astacin [EC:3.4.24.21] (A) -- [O] Posttranslational modification, protein turnover, chaperones Astacin (Peptidase family M12A) Metalloendopeptidase {ECO:0000256|RuleBase:RU361183} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein NAS-33 [Caenorhabditis elegans] C08F11.12 gene20685 183 175 257 121 74 79 160.084 134.783 202.933 106.236 87.2278 84.2381 0.00136321260672682 -1.18231162323277 down -- -- -- -- -- -- -- Protein of unknown function (DUF1505) Putative uncharacterized protein {ECO:0000313|EMBL:EFO92777.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein C08F11.12 [Caenorhabditis elegans] C34F11.2 gene6002 42 70 71 29 24 32 9.636610862182 11.05948437171 6.48467386152 5.1271004162 7.758492164 3.236804 0.00905027682818816 -1.12015312029424 down -- -- -- -- -- -- -- -- Protein C34F11.2 {ECO:0000313|EMBL:CCD65823.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein C34F11.2 [Caenorhabditis elegans] fat-2 gene20439 9437 9317 10553 30003 28698 34458 617.29604591 599.531349576 679.277134704 1958.691142635 2007.593322089 2390.825157528 4.12244815022824e-18 1.6541665597257 up [I] Lipid transport and metabolism Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (GO:0016717);; Biological Process: oxidation-reduction process (GO:0055114);; K10257|0|cel:CELE_W02A2.1|fat-2; Protein FAT-2; K10257 omega-3 fatty acid desaturase (delta-15 desaturase) [EC:1.14.19.-] (A) Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212) -- -- Fatty acid desaturase;; Domain of unknown function (DUF3474) Putative uncharacterized protein {ECO:0000313|EMBL:EGT37131.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein FAT-2 [Caenorhabditis elegans] mxl-3 gene45332 1162 1069 1716 3851 4107 4172 77.8981702970343 70.275380995 111.9857228477 252.40920293023 257.829310812 270.592177000002 1.98967606120155e-19 1.60474501732948 up -- -- Molecular Function: protein dimerization activity (GO:0046983);; K04453|1.43151e-112|cel:CELE_F46G10.6|mxl-3; Protein MXL-3; K04453 Max protein (A) MAPK signaling pathway (ko04010) [K] Transcription Helix-loop-helix DNA-binding domain Protein MXL-3 {ECO:0000313|EMBL:CAA94125.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein MXL-3 [Caenorhabditis elegans] cyp-37A1 gene9085 584 556 465 1602 1673 2073 21.3077166713079 19.8009846047 16.942250027 56.439805 61.2917200000099 74.9406070000898 2.49142372218965e-16 1.72287691161805 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17959|0|cel:CELE_F01D5.9|cyp-37A1; Protein CYP-37A1; K17959 cytochrome P450, family 37 (A) -- [QI] Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism Cytochrome P450 Protein CYP-37A1 {ECO:0000313|EMBL:CAB04044.2} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein CYP-37A1 [Caenorhabditis elegans] F57B9.8 gene11274 40 55 51 13 26 18 1.96005 2.79466 2.56601 0.666052 1.38246 0.988004 0.00278965992739467 -1.36981318853017 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain;; SH2 domain Protein F57B9.8 {ECO:0000313|EMBL:CCD70317.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein F57B9.8 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_342 25 38 34 5 5 5 1.06328 1.58139 1.44905 0.212149 0.216936 0.225439 1.15482287591003e-06 -2.70661810929515 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; Protein tyrosine kinase;; Protein kinase domain Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA04113c} OS=Caenorhabditis japonica PE=4 SV=1 R General function prediction only PREDICTED: tyrosine-protein kinase Fer [Felis catus] str-41 gene35320 5 4 0 33 27 32 0.471584 0.417394 0.0836309 3.13868 2.71348 3.23733 3.81109991859246e-08 3.34153022414533 up -- -- -- K08473|0|cel:CELE_R13D7.1|str-41; Protein STR-41; K08473 nematode chemoreceptor (A) -- -- -- Serpentine type 7TM GPCR chemoreceptor Str;; Serpentine type 7TM GPCR chemoreceptor Srj;; Serpentine type 7TM GPCR chemoreceptor Srd;; Serpentine type 7TM GPCR chemoreceptor Srh Protein STR-41 {ECO:0000313|EMBL:CCD83340.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein STR-41 [Caenorhabditis elegans] C04G6.2 gene5953 86 111 112 48 61 45 15.55872 20.13862 19.45799 9.33724 11.76277 7.66668 0.00494147684935623 -1.01850807919246 down -- -- -- -- -- -- -- Caenorhabditis protein of unknown function, DUF282 Protein C04G6.2 {ECO:0000313|EMBL:CCD63060.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C04G6.2 [Caenorhabditis elegans] C49F5.7 gene44878 74 93 81 50 25 40 175.1453 185.6778 193.78149 127.21755 105.46633 126.9024 0.00371476110192555 -1.12324632978705 down -- -- -- -- -- -- -- -- Protein C49F5.7 {ECO:0000313|EMBL:CAB03980.2} OS=Caenorhabditis elegans PE=4 SV=2 BK Chromatin structure and dynamics;; Transcription Protein C49F5.7 [Caenorhabditis elegans] bah-1 gene3159 32 47 31 7 5 3 1.436864 1.929547 1.44582533214 0.32724330555 0.18589979 0.14097352813 8.47835362511619e-08 -2.88870510289354 down -- -- -- -- -- -- -- Glycosyltransferase family 92 Protein BAH-1 {ECO:0000313|EMBL:CAA18365.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein BAH-1 [Caenorhabditis elegans] gstk-1 gene7738 553 572 650 231 241 227 55.841480843 57.87857169127 65.6129948344 23.7553695465352 25.4457855252012 24.39814917 1.30156440750709e-09 -1.3588209278078 down -- -- Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; K13299|5.91745e-157|cel:CELE_ZK1320.1|gstk-1; Protein GSTK-1; K13299 glutathione S-transferase kappa 1 [EC:2.5.1.18] (A) Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Peroxisome (ko04146) -- -- DSBA-like thioredoxin domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT51862.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 C Energy production and conversion Protein GSTK-1 [Caenorhabditis elegans] grd-6 gene36028 769 793 755 330 365 393 17.911423049165 17.8405200315062 16.79531898 7.292073634 7.7597845901 7.599835216 3.14709426375509e-07 -1.10434357667977 down -- -- -- -- -- -- -- Ground-like domain Protein GRD-6 {ECO:0000313|EMBL:CCD65450.1} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only GRD-6 [Caenorhabditis elegans] C13G3.1 gene36767 151 130 117 381 309 376 65.819 51.0827 46.2959 163.335 153.498 183.951 1.61066172575854e-08 1.40707672855907 up -- -- -- -- -- -- -- -- Protein C13G3.1 {ECO:0000313|EMBL:CAA98421.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C13G3.1 [Caenorhabditis elegans] F13E9.14 gene19516 28 16 7 46 61 48 3.51937 1.99208 0.921116 5.44885 7.92109 5.88348 0.000397078942702759 1.59025241822016 up -- -- -- -- -- -- -- Domain of unknown function DUF148 Protein F13E9.14 {ECO:0000313|EMBL:CAM06587.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F13E9.14 [Caenorhabditis elegans] Y87G2A.2 gene3814 295 294 296 644 543 620 20.84131 19.18673 18.92346 42.0832 37.9344 40.1279 8.82637678502503e-06 1.01548561605554 up [I] Lipid transport and metabolism -- -- -- [I] Lipid transport and metabolism Thioesterase-like superfamily;; Acyl-CoA thioesterase Protein Y87G2A.2 {ECO:0000313|EMBL:CAB60427.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein Y87G2A.2 [Caenorhabditis elegans] F01G10.4 gene19288 67 50 17 115 97 113 4.44384759917 3.65514363944 1.0218566883 8.20722 6.713472 8.77052 0.000646738754885529 1.2649744315594 up -- -- -- -- -- -- -- -- Protein F01G10.4 {ECO:0000313|EMBL:CAB02895.3} OS=Caenorhabditis elegans PE=4 SV=3 V Defense mechanisms Protein F01G10.4 [Caenorhabditis elegans] acdh-1 gene1555 29 21 18 328 226 311 1.5521626318 1.179086 0.96613925847 17.55360336049 12.4778182351 17.74160269175 1.66412610465633e-24 3.65453078450421 up [I] Lipid transport and metabolism Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; K09478|0|cbr:CBG12644|Cbr-acdh-1; C. briggsae CBR-ACDH-1 protein; K09478 short/branched chain acyl-CoA dehydrogenase [EC:1.3.99.12] (A) Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Fatty acid metabolism (ko01212) [I] Lipid transport and metabolism Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, middle domain Protein ACDH-1, isoform a {ECO:0000313|EMBL:CCD68091.1} OS=Caenorhabditis elegans PE=3 SV=1 P Inorganic ion transport and metabolism Protein ACDH-1, isoform a [Caenorhabditis elegans] F07F6.1 gene6089 79 125 134 47 43 59 4.39193 6.91715 7.42441 2.6489 2.51495 3.61174 0.00280390238375587 -1.19548330880338 down -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EGT56389.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein F07F6.1 [Caenorhabditis elegans] dhs-8 gene9195 645 599 683 1913 1346 1867 37.16283547 33.143020528032 36.1448661794767 106.744878723 78.0125467 115.20217942 4.09212727519809e-08 1.39670078640879 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism short chain dehydrogenase;; KR domain;; NAD dependent epimerase/dehydratase family Protein DHS-8, isoform a {ECO:0000313|EMBL:CAB05779.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein DHS-8, isoform a [Caenorhabditis elegans] C09G1.2 gene46270 23 30 11 82 56 64 0.288938860000805 0.36956470674 0.1363890171 0.899478799 0.667912165403 0.7073167451 5.60025282153749e-05 1.64538249052449 up -- -- -- -- -- -- -- -- Protein C09G1.2 {ECO:0000313|EMBL:CAA90539.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C09G1.2 [Caenorhabditis elegans] oac-14 gene44249 303 341 451 4150 4214 4796 9.6619983203 10.78025223 14.1237436164 132.9698626708 140.150900416 162.486500911 1.3809470453054e-80 3.57268958013784 up [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [R] General function prediction only Acyltransferase family Protein OAC-14 {ECO:0000313|EMBL:CAA90058.1} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein OAC-14 [Caenorhabditis elegans] B0507.7 gene35826 23 32 20 84 61 47 1.075665 2.313629 0.822504 4.30667 2.80928 2.84484 0.0043754203777899 1.34223461322221 up -- -- -- -- -- -- -- -- Protein B0507.7 {ECO:0000313|EMBL:CCD62077.2} OS=Caenorhabditis elegans PE=4 SV=4 S Function unknown B0507.7 [Caenorhabditis elegans] ZK228.3 gene39974 526 673 501 254 197 197 35.190931 44.4640125 34.2357773215 16.8457004055017 13.9149419952 13.4026248579 1.02546862964177e-09 -1.40536066875941 down -- -- -- -- -- -- -- -- Protein ZK228.3 {ECO:0000313|EMBL:CAB04995.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein ZK228.3 [Caenorhabditis elegans] oac-56 gene22832 258 207 143 94 60 108 9.806815 7.811302 5.28565957 3.610892531 2.445621793343 4.401378 0.00821739426136978 -1.22841970121211 down [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- -- -- Acyltransferase family Protein OAC-56 {ECO:0000313|EMBL:CAB60446.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein OAC-56 [Caenorhabditis elegans] F38A1.9 gene13515 42 67 51 177 182 210 2.220776158906 2.86189200000479 1.841077971 6.95890522626 8.033144 8.701215 6.18673213626461e-10 1.81736780757372 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms -- Protein F38A1.9 {ECO:0000313|EMBL:CCD63953.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein F38A1.9 [Caenorhabditis elegans] ZK813.6 gene41743 22 27 40 9 12 9 1.67289 1.5388827541 2.69801 0.86406102536 0.814943 0.52215142929 0.00393137815374114 -1.58344158445077 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- [R] General function prediction only Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain Protein ZK813.6 {ECO:0000313|EMBL:CCD63039.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK813.6 [Caenorhabditis elegans] C07E3.4 gene7967 31 47 63 12 8 18 0.998483 1.55457 2.08656 0.406703 0.279805 0.634285 0.00217254413789302 -1.90588235052106 down -- -- Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase Protein C07E3.4 {ECO:0000313|EMBL:CAA90095.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein C07E3.4 [Caenorhabditis elegans] F15H10.8 gene36482 255 234 156 103 98 124 18.0168 16.0527 10.6376 7.38407 7.42371 9.37608 0.00421114436016395 -1.00223236919638 down -- -- -- -- -- -- -- -- Protein F15H10.8 {ECO:0000313|EMBL:CAB60280.2} OS=Caenorhabditis elegans PE=4 SV=1 DO Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones Protein F15H10.8 [Caenorhabditis elegans] ceh-79 gene37856 258 295 328 525 604 687 8.0261893282 8.306188464 7.66896900000007 15.60037308441 16.4991270234 21.191916 6.31765308975992e-06 1.02969222324558 up -- -- -- -- -- -- -- Homeobox domain Protein CEH-79 {ECO:0000313|EMBL:CAB02783.3} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein CEH-79 [Caenorhabditis elegans] chil-22 gene7668 253 286 201 558 485 670 12.1952234 13.77605 9.57228 27.752228284 24.04542403 34.64077964 6.91076065865797e-07 1.19764399027827 up [G] Carbohydrate transport and metabolism Biological Process: carbohydrate metabolic process (GO:0005975);; -- -- [G] Carbohydrate transport and metabolism Glycosyl hydrolases family 18 Protein CHIL-22 {ECO:0000313|EMBL:CAA93870.2} OS=Caenorhabditis elegans PE=3 SV=2 G Carbohydrate transport and metabolism Protein R09D1.10 [Caenorhabditis elegans] clec-51 gene18472 98 104 95 251 177 185 8.77680000045266 9.18568 8.98427 22.6929000003809 16.1439000000047 17.4237 0.000449837788026664 1.03081720257378 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-51, isoform a {ECO:0000313|EMBL:CCD61388.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein CLEC-51 [Caenorhabditis elegans] eol-1 gene38106 86 77 44 166 121 195 5.711672249 4.85481401 2.78885572 9.97169374 8.03760729 12.81304721 0.00236854760465446 1.20600925540359 up -- -- -- -- -- [L] Replication, recombination and repair RAI1 like PD-(D/E)XK nuclease Protein T26F2.3 {ECO:0000313|EMBL:CAN86644.3} OS=Caenorhabditis elegans PE=4 SV=3 L Replication, recombination and repair Protein T26F2.3 [Caenorhabditis elegans] C16C8.18 gene5420 69 76 84 29 34 25 6.12705 6.66028 7.39099 2.6152647 3.28743 2.51745 0.000374735895718575 -1.39406514680942 down -- -- -- -- -- -- -- -- Protein C16C8.18 {ECO:0000313|EMBL:CCD64706.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C16C8.18 [Caenorhabditis elegans] C04F12.7 gene2576 215 288 271 124 108 102 38.6322 48.2826 45.2522 21.8143 20.5107 19.077 5.62242847374696e-06 -1.22663219416431 down -- -- -- -- -- -- -- -- Protein C04F12.7 {ECO:0000313|EMBL:CAB62797.1} OS=Caenorhabditis elegans PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein C04F12.7 [Caenorhabditis elegans] fipr-1 gene37477 24 41 26 15 7 12 308.853 513.659 334.036 221.311 191.276 257.968 0.00849493767075798 -1.43398826755612 down -- -- -- -- -- -- -- -- Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA27863} OS=Caenorhabditis japonica PE=4 SV=1 -- -- Protein FIPR-1 [Caenorhabditis elegans] T24B8.5 gene7533 30 21 55 1 3 2 55.3849 34.159 93.2691 1.88012 10.8549 4.8866 0.000544003904465688 -4.15774254686678 down -- -- -- -- -- -- -- ShK domain-like Protein T24B8.5 {ECO:0000313|EMBL:CAA92755.2} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein T24B8.5 [Caenorhabditis elegans] F35E12.6 gene38004 5045 6704 5286 2939 2763 2782 299.82561 396.70992 299.79617 157.81395 143.0566 149.34606 1.60679578038391e-07 -1.01924750397147 down -- -- -- -- -- -- -- CUB-like domain Protein F35E12.6 {ECO:0000313|EMBL:CAB04273.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F35E12.6 [Caenorhabditis elegans] abf-5 gene45143 741 879 688 1653 1434 1733 98.1089 119.8704 113.91235 260.146691 240.3105 249.269 8.07273939219381e-08 1.04878879888885 up -- -- -- -- -- -- -- -- Protein ABF-5 {ECO:0000313|EMBL:CAA90673.1} OS=Caenorhabditis elegans PE=2 SV=1 K Transcription Protein ABF-5 [Caenorhabditis elegans] ins-33 gene3836 92 89 81 234 161 147 53.5078 45.9444 44.3468 132.709 121.907 97.7472 0.00455882401791028 1.03382864881848 up -- -- Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; -- -- -- -- Nematode insulin-related peptide beta type Protein INS-33 {ECO:0000313|EMBL:CAB63330.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein INS-33 [Caenorhabditis elegans] gmd-2 gene3442 316 218 303 114 86 72 15.4997 10.2919 14.4573 5.42184 4.33689 3.50275 9.02739323028878e-08 -1.63742743824163 down [M] Cell wall/membrane/envelope biogenesis Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; K01711|0|cel:CELE_F56H6.5|gmd-2; Protein GMD-2; K01711 GDPmannose 4,6-dehydratase [EC:4.2.1.47] (A) Fructose and mannose metabolism (ko00051);; Amino sugar and nucleotide sugar metabolism (ko00520) [G] Carbohydrate transport and metabolism NAD dependent epimerase/dehydratase family;; RmlD substrate binding domain;; Polysaccharide biosynthesis protein Putative uncharacterized protein {ECO:0000313|EMBL:EGT46220.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 R General function prediction only Protein GMD-2 [Caenorhabditis elegans] wht-5 gene20113 67 99 99 32 53 43 2.17031 3.24593 3.21526 1.08162 1.78184 1.54176 0.00510802629087356 -1.06300644314215 down [V] Defense mechanisms Molecular Function: ATP binding (GO:0005524);; Cellular Component: membrane (GO:0016020);; Molecular Function: ATPase activity (GO:0016887);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism ABC-2 type transporter;; ABC transporter;; AAA domain;; Protein of unknown function, DUF258 Protein WHT-5 {ECO:0000313|EMBL:CAA93461.1} OS=Caenorhabditis elegans PE=4 SV=1 F Nucleotide transport and metabolism Protein WHT-5 [Caenorhabditis elegans] uggt-2 gene2400 116 120 138 255 366 329 1.838833 1.814269 1.941975 3.771753 5.76532 5.06415 2.06532328931102e-07 1.33104082958236 up -- -- Molecular Function: UDP-glucose:glycoprotein glucosyltransferase activity (GO:0003980);; Biological Process: protein glycosylation (GO:0006486);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; -- -- [G] Carbohydrate transport and metabolism UDP-glucose:Glycoprotein Glucosyltransferase;; Glycosyl transferase family 8 Protein UGGT-2 {ECO:0000313|EMBL:CAB04207.2} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein UGGT-2 [Caenorhabditis elegans] F58A6.5 gene5977 61 61 50 29 21 27 5.72824 5.63028 4.67496 2.77968 2.11077 2.76578 0.00720268221310082 -1.17362490579529 down -- -- -- -- -- -- -- Interactor of ZYG-11 Protein F58A6.5 {ECO:0000313|EMBL:CCD65836.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein F58A6.5 [Caenorhabditis elegans] C31H2.4 gene42343 54 73 85 207 199 181 3.18961 4.125368391 4.89646 12.05117 11.7348880245 11.02677 5.25029592041405e-07 1.45485100191754 up [ER] Amino acid transport and metabolism;; General function prediction only -- K00457|0|cel:CELE_C31H2.4|C31H2.4; Protein C31H2.4; K00457 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] (A) Ubiquinone and other terpenoid-quinone biosynthesis (ko00130);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360) [E] Amino acid transport and metabolism Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase-like domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT29946.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 S Function unknown Protein C31H2.4 [Caenorhabditis elegans] pud-3 gene33541 285 358 543 13 14 12 61.5005 71.0787 110.23 2.79396 3.4527 2.8058 1.25876594404074e-11 -4.94140260885981 down -- -- -- -- -- -- -- -- Protein PUD-3, isoform a {ECO:0000313|EMBL:CCD69543.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein PUD-3, isoform a [Caenorhabditis elegans] F40G12.5 gene38207 154 132 66 363 366 363 13.6971 10.52837 5.15602 28.2776 30.7806 32.1343 6.20886704319988e-11 1.62008509238981 up -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein F40G12.5 {ECO:0000313|EMBL:CAB01183.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein F40G12.5 [Caenorhabditis elegans] ptr-13 gene8224 1159 1052 976 2016 2231 2371 29.4535455 21.424507528573 20.7021471354183 42.5880593587 49.5104200000003 55.016554 5.14195054909005e-08 1.04035294339627 up -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [R] General function prediction only Patched family;; Sterol-sensing domain of SREBP cleavage-activation;; Protein export membrane protein Protein PTR-13 {ECO:0000313|EMBL:CAA87375.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein PTR-13 [Caenorhabditis elegans] cyp-35B1 gene34084 214 211 110 442 411 430 9.2704 9.29376 4.83365 19.6723 18.9023 20.2205 2.08399241587011e-07 1.24871751364911 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17957|0|cel:CELE_K07C6.4|cyp-35B1; Protein CYP-35B1; K17957 cytochrome P450, family 35 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-35B1 {ECO:0000313|EMBL:CCD72733.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein CYP-35B1 [Caenorhabditis elegans] Y11D7A.8 gene18853 38 39 29 81 97 87 1.72482 1.857531 1.278016 3.64615 4.64567 4.20377 0.000497566890201957 1.30855700562797 up -- -- -- -- -- -- -- Protein of unknown function (DUF1679);; Ecdysteroid kinase;; Phosphotransferase enzyme family Protein Y11D7A.8 {ECO:0000313|EMBL:CAA21584.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein Y11D7A.8 [Caenorhabditis elegans] str-112 gene35213 44 22 30 324 302 356 3.95725 1.941291 2.554608 27.74342 28.7713 32.3905 3.35372796228397e-33 3.33947404654456 up -- -- -- K08473|0|cel:CELE_F10D2.4|str-112; Protein STR-112; K08473 nematode chemoreceptor (A) -- -- -- Serpentine type 7TM GPCR chemoreceptor Str;; Serpentine type 7TM GPCR chemoreceptor Srj;; Serpentine type 7TM GPCR chemoreceptor Srd;; Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Sri Protein STR-112 {ECO:0000313|EMBL:CCD69118.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein STR-112 [Caenorhabditis elegans] F49C12.3 gene18868 7 9 1 32 34 41 0.531464 0.659667 0.130529 2.385916 2.60786060229 3.30861 8.51343357577708e-07 2.64314247607257 up -- -- -- -- -- -- -- Nucleotide-diphospho-sugar transferase Protein F49C12.3 {ECO:0000313|EMBL:CAA92508.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown F49C12.3 [Caenorhabditis elegans] ZC376.3 gene38174 179 181 120 464 371 500 5.34647 5.54059 3.59778 14.3865 11.8576 16.7015 7.00191981559423e-10 1.46222135060522 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein ZC376.3 {ECO:0000313|EMBL:CAB00887.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZC376.3 [Caenorhabditis elegans] F15D3.6 gene3194 807 793 996 1818 1918 2111 64.56573 58.29219262 73.95481 139.762940026136 154.1808 173.24351 1.00969421837282e-09 1.15700143806576 up -- -- -- -- -- [U] Intracellular trafficking, secretion, and vesicular transport PRELI-like family Protein F15D3.6 {ECO:0000313|EMBL:CAB02955.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein F15D3.6 [Caenorhabditis elegans] hsp-12.3 gene18921 47 58 63 235 137 156 45.7819 50.7777 59.4739 226.88 185.13 180.001 0.000412539365789955 1.63693364605032 up -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Hsp20/alpha crystallin family Protein HSP-12.3 {ECO:0000313|EMBL:CAA92770.1} OS=Caenorhabditis elegans PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein HSP-12.3 [Caenorhabditis elegans] Y58A7A.5 gene34440 249 472 557 2128 1534 2003 18.3144 35.3324 41.9397 162.026 116.828 157.43 4.12924833540956e-14 2.13373951416351 up -- -- -- -- -- -- -- -- Protein Y58A7A.5 {ECO:0000313|EMBL:CCD63024.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein Y58A7A.5 [Caenorhabditis elegans] col-106 gene13562 6949 6973 11410 2951 2263 2755 420.381 397.143 668.338 167.177 132.382 156.024 0.000594205662019433 -1.68394428700078 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-106 {ECO:0000313|EMBL:CCD72602.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-106 [Caenorhabditis elegans] K01D12.9 gene37495 131 155 143 53 46 38 148.964 157.411 154.613 60.9757 79.8185 54.2872 1.64216253212656e-07 -1.66116411943108 down -- -- -- -- -- -- -- -- Protein K01D12.9 {ECO:0000313|EMBL:CAA99865.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein K01D12.9 [Caenorhabditis elegans] hil-1 gene38478 1517 1352 911 2504 2440 2714 110.4745524 89.788024197 66.0352496600135 166.938429593 160.03774719 187.34063 1.09348397431049e-07 1.00504912396786 up -- -- Cellular Component: nucleosome (GO:0000786);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; -- -- [B] Chromatin structure and dynamics linker histone H1 and H5 family CRE-HIL-1 protein {ECO:0000313|EMBL:EFP05958.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 B Chromatin structure and dynamics Protein HIL-1 [Caenorhabditis elegans] F35E2.5 gene3271 66 70 59 25 15 15 1.9465522890597 1.993996492327 1.7265349389 0.722073 0.408772300000928 0.4323939 8.08045934549382e-06 -1.84083361645228 down -- -- -- -- -- -- -- Domain of unknown function (DUF316) Protein F35E2.5 {ECO:0000313|EMBL:CAB04281.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F35E2.5 [Caenorhabditis elegans] col-137 gene31124 535 478 335 106 73 62 24.9579 21.3702 14.82434 4.36416 3.03446 2.64412 1.13494532512024e-10 -2.49833939913794 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-137 {ECO:0000313|EMBL:CAB61143.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein COL-137 [Caenorhabditis elegans] C02F5.5 gene11691 64 67 60 23 26 30 15.5222 14.8295 13.5324 5.48292 7.08418 7.76849 0.00208989205134278 -1.28716555691998 down -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EFP09385.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein C02F5.5 [Caenorhabditis elegans] irg-3 gene33618 809 689 497 316 249 243 110.272653308342 87.45937875 63.794816 38.5869850460918 34.5891500024404 30.826834 0.000163964798153271 -1.31823701874215 down -- -- -- -- -- -- -- -- Protein IRG-3 {ECO:0000313|EMBL:CCD66101.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein IRG-3 [Caenorhabditis elegans] W05E10.1 gene37159 595 658 450 275 204 192 35.8937 40.2538 27.1686 17.1827 13.3668 12.911 9.51091514553254e-07 -1.35775378410845 down -- -- Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [R] General function prediction only Major Facilitator Superfamily Protein W05E10.1 {ECO:0000313|EMBL:CAB01247.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein W05E10.1 [Caenorhabditis elegans] col-8 gene11300 3103 3463 6440 1251 875 1206 166.7447 173.3959 340.33 64.3902 43.9573 60.26897 0.00848717926292409 -1.98044005360957 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain CRE-COL-8 protein {ECO:0000313|EMBL:EFO90232.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 W Extracellular structures Protein COL-8 [Caenorhabditis elegans] col-159 gene37822 8389 8154 6548 3627 3379 3556 430.239 396.423 319.046 172.019 160.423 164.52 3.60804168839092e-10 -1.14231906718011 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-159 {ECO:0000313|EMBL:CAB01509.1} OS=Caenorhabditis elegans PE=4 SV=1 D Cell cycle control, cell division, chromosome partitioning Protein COL-159 [Caenorhabditis elegans] msp-64 gene6267 78 118 109 42 32 70 36.4573 49.1026 47.9566 19.0802 18.0078 34.4839 0.0077113168278104 -1.0959288702986 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein MSP-31 [Caenorhabditis elegans] col-162 gene37901 2849 2851 2460 1376 1056 1220 148.097918 143.54827 126.5798 65.25523156364 44.515452396176 52.04102485367 2.3789528277764e-10 -1.17413504922994 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-162 {ECO:0000313|EMBL:CAA16275.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-162 [Caenorhabditis elegans] C23H5.8 gene13682 202 171 166 741 605 689 23.6675577982 19.048268 17.329059985 79.5627548275 75.985762196 79.048009058 3.59080423462967e-18 1.90216797035214 up -- -- -- -- -- -- -- -- Protein C23H5.8, isoform a {ECO:0000313|EMBL:CCD65346.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C23H5.8, isoform a [Caenorhabditis elegans] T28C12.4 gene34862 5852 5990 6183 15595 16502 17903 136.7815246118 137.897452678568 142.370168197607 353.176901540411 365.626061769936 402.369513782774 1.21635432760651e-15 1.45792890183878 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; K01066|0|cel:CELE_T28C12.4|T28C12.4; Protein T28C12.4, isoform A; K01066 esterase / lipase [EC:3.1.1.-] (A) -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein T28C12.4, isoform a {ECO:0000313|EMBL:CCD69476.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein T28C12.4, isoform a [Caenorhabditis elegans] T12G3.2 gene19993 2281 2140 2394 4691 5180 4265 41.6782106 40.188411829901 44.56115664075 88.7716545297165 97.2000714526864 84.6707513340042 1.43424841469647e-08 1.0381517278934 up -- -- -- -- -- -- -- -- Protein T12G3.2, isoform d {ECO:0000313|EMBL:CBK19474.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T12G3.2, isoform d [Caenorhabditis elegans] fbxa-72 gene33087 259 248 165 107 72 80 17.24690639534 16.3934250869 10.7927798318 7.3110798126 5.1111760172 5.8600246710013 7.32691712574192e-05 -1.389700997465 down -- -- -- -- -- -- -- FTH domain Protein FBXA-72 {ECO:0000313|EMBL:CCD70340.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein FBXA-72 [Caenorhabditis elegans] col-124 gene19280 7886 11715 14914 4153 4043 4768 329.9681 434.3986 558.5196 155.0785 141.2819 170.8392 0.0026105234743889 -1.42698755714774 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-124 {ECO:0000313|EMBL:CAB97232.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein COL-124 [Caenorhabditis elegans] C33H5.2 gene18342 17 19 15 122 98 137 0.737117 0.826466 0.627407 5.28815 4.2749 6.14414 5.70618608696415e-15 2.79370939207601 up -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Putative uncharacterized protein {ECO:0000313|EMBL:EFP05639.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 I Lipid transport and metabolism Protein C33H5.2 [Caenorhabditis elegans] nit-1 gene10312 4647 4643 4267 20612 18478 22741 300.839711002 302.210125 275.3440279 1357.41132189 1252.85000010384 1565.1700736421 8.62510567011154e-33 2.1753186365865 up [R] General function prediction only Biological Process: nitrogen compound metabolic process (GO:0006807);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810);; K01501|0|cel:CELE_ZK1058.6|nit-1; Protein NIT-1; K01501 nitrilase [EC:3.5.5.1] (A) Tryptophan metabolism (ko00380);; Cyanoamino acid metabolism (ko00460);; Nitrogen metabolism (ko00910) [E] Amino acid transport and metabolism Carbon-nitrogen hydrolase Protein NIT-1 {ECO:0000313|EMBL:CAA84681.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein NIT-1 [Caenorhabditis elegans] B0280.7 gene11334 355 339 233 174 112 127 23.47603 22.69703 15.35998 11.71668 8.14776 9.51247 0.000389664861806909 -1.18074392482604 down -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EFP09501.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only Protein B0280.7 [Caenorhabditis elegans] C06B3.7 gene38075 422 493 507 955 911 1045 30.2435 35.3081158 35.40865 66.28307813 65.1839 76.30303 1.1829616139304e-06 1.01956665400366 up -- -- -- -- -- -- -- -- Protein C06B3.7 {ECO:0000313|EMBL:CAB01117.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C06B3.7 [Caenorhabditis elegans] C50A2.3 gene13489 85 88 51 162 131 171 6.4357042 6.823716217751 4.023232249772 12.7698272673 12.012636025 12.172566836 0.00115194213483345 1.03733495391063 up -- -- -- -- -- -- -- -- Protein C50A2.3, isoform b {ECO:0000313|EMBL:CDH93333.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown C50A2.3, isoform b [Caenorhabditis elegans] ssq-4 gene14832 785 916 967 418 446 454 44.71233 53.0033 57.4982 22.86768 25.81303 24.58202 1.16240575290534e-06 -1.03140997407433 down -- -- -- -- -- -- -- -- Protein SSQ-4 {ECO:0000313|EMBL:CCD63834.1} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only hypothetical protein ZC477.8 - Caenorhabditis elegans C40H1.8 gene12066 67 72 49 172 116 173 4.680519 4.808101 3.215277 12.24568 8.28208 12.76418 6.56799638128177e-05 1.28033536948502 up -- -- Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Lipase (class 3) Protein C40H1.8 {ECO:0000313|EMBL:CAE17740.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C40H1.8 [Caenorhabditis elegans] F55G1.9 gene18217 1192 1180 974 448 349 369 92.8137 91.6519 75.2369 35.1736 28.803 30.7528 1.8622768093394e-14 -1.53513187407592 down [E] Amino acid transport and metabolism -- K00286|0|cel:CELE_F55G1.9|F55G1.9; Protein F55G1.9; K00286 pyrroline-5-carboxylate reductase [EC:1.5.1.2] (A) Arginine and proline metabolism (ko00330);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Pyrroline-5-carboxylate reductase dimerisation;; NADP oxidoreductase coenzyme F420-dependent Pyrroline-5-carboxylate reductase {ECO:0000256|RuleBase:RU003903} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 S Function unknown Protein F55G1.9 [Caenorhabditis elegans] ugt-32 gene34052 39 56 52 183 153 158 2.2918940144931 3.86329748388111 2.560654600339 8.831552 5.98605267530602 6.20661 1.35994065204203e-08 1.73464954769674 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase Protein UGT-32 {ECO:0000313|EMBL:CCD64887.1} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein UGT-32 [Caenorhabditis elegans] pept-1 gene42886 9616 9680 5779 3180 2855 2720 191.8217 192.6601 113.8908 64.0012 56.7512 55.1479 0.000118664325749759 -1.53161098041643 down [E] Amino acid transport and metabolism Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; K14206|0|cel:CELE_K04E7.2|pept-1; Protein PEPT-1; K14206 solute carrier family 15 (oligopeptide transporter), member 1 (A) -- [E] Amino acid transport and metabolism POT family CRE-PEPT-1 protein {ECO:0000313|EMBL:EFO82401.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein PEPT-1 [Caenorhabditis elegans] pes-8 gene43989 376 482 412 189 198 205 14.81934 18.55205 15.92094 7.1528 7.70395 7.66406 4.20655331756303e-06 -1.11467090761798 down -- -- -- -- -- -- -- -- Protein PES-8 {ECO:0000313|EMBL:CCD61934.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein PES-8 [Caenorhabditis elegans] T08E11.1 gene4824 60 76 55 131 149 190 2.05156 2.62521 1.86426 4.61704 5.28436 7.03144 3.72526718710109e-05 1.28628021081615 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein T08E11.1 {ECO:0000313|EMBL:CCD63720.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein T08E11.1 [Caenorhabditis elegans] F37A4.5 gene11198 344 449 496 210 189 222 12.860303053 18.164715 16.26298 7.807425829 6.517347721 7.271408 1.47086419963061e-05 -1.0677740575111 down [R] General function prediction only Molecular Function: protein binding (GO:0005515);; K03030|0|cel:CELE_F37A4.5|F37A4.5; Protein F37A4.5; K03030 26S proteasome regulatory subunit N11 (A) Proteasome (ko03050) [O] Posttranslational modification, protein turnover, chaperones JAB1/Mov34/MPN/PAD-1 ubiquitin protease;; Maintenance of mitochondrial structure and function;; Prokaryotic homologs of the JAB domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT51938.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein F37A4.5 [Caenorhabditis elegans] F36D3.8 gene39222 62 74 81 33 31 38 2.416685 2.754341796 3.961469 1.632184 1.47833260594 1.6258724 0.00647585813253282 -1.10321700554288 down -- -- -- -- -- -- -- Protein of unknown function (DUF1248) Protein F36D3.8 {ECO:0000313|EMBL:CAB04320.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F36D3.8 [Caenorhabditis elegans] Y1A5A.1 gene10324 58 80 82 37 20 25 11.2319 14.2499 14.8438 7.04144 4.175 5.22229 0.000288776525016421 -1.43879227868661 down -- -- -- -- -- [TZ] Signal transduction mechanisms;; Cytoskeleton LIM domain Protein Y1A5A.1 {ECO:0000313|EMBL:CAA15978.1} OS=Caenorhabditis elegans PE=4 SV=1 TZ Signal transduction mechanisms;; Cytoskeleton Protein Y1A5A.1 [Caenorhabditis elegans] F41C3.7 gene5809 41 32 15 64 79 57 2.244204 1.873498 0.875947 3.710806 4.51531 3.503189 0.00493153642212866 1.17118312598641 up -- -- -- -- -- -- -- -- Protein F41C3.7 {ECO:0000313|EMBL:CCD65862.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F41C3.7 [Caenorhabditis elegans] F49C12.6 gene18872 675 697 548 1726 1790 2227 21.339215 19.19761 17.650101 58.463531 57.0827060006172 78.8780567652 4.23772240235933e-14 1.56733068509939 up -- -- Molecular Function: carbohydrate transmembrane transporter activity (GO:0015144);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: carbohydrate transmembrane transport (GO:0034219);; -- -- -- -- CEO family (DUF1632);; Sugar transport protein Protein F49C12.6 {ECO:0000313|EMBL:CAA92510.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F49C12.6 [Caenorhabditis elegans] sodh-1 gene37245 3941 2959 4418 31073 31392 31306 250.834 185.024 278.929 1959.36 1960.34 2009.37 1.13301482170732e-56 3.03543454176075 up [R] General function prediction only Biological Process: oxidation-reduction process (GO:0055114);; K13953|0|cel:CELE_K12G11.3|sodh-1; Protein SODH-1; K13953 alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] (A) Glycolysis / Gluconeogenesis (ko00010);; Fatty acid degradation (ko00071);; Tyrosine metabolism (ko00350);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Degradation of aromatic compounds (ko01220) [Q] Secondary metabolites biosynthesis, transport and catabolism Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase Protein CBR-SODH-1 {ECO:0000313|EMBL:CAP39759.1} OS=Caenorhabditis briggsae PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein SODH-1 [Caenorhabditis elegans] gcy-17 gene383 43 41 38 85 82 103 0.73739281201 0.7037368654462 0.6331845 1.4627021386 1.4382507078 1.875892007 0.00268882333838895 1.1322151389084 up [T] Signal transduction mechanisms Molecular Function: guanylate cyclase activity (GO:0004383);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: cGMP biosynthetic process (GO:0006182);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; K12323|0|cbr:CBG03898|Hypothetical protein CBG03898; K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2] (A) Purine metabolism (ko00230) [T] Signal transduction mechanisms Adenylate and Guanylate cyclase catalytic domain;; Receptor family ligand binding region;; Protein tyrosine kinase;; Protein kinase domain;; Heme NO binding associated Guanylate cyclase {ECO:0000256|RuleBase:RU003431} OS=Caenorhabditis elegans PE=3 SV=1 T Signal transduction mechanisms GCY-17, isoform a [Caenorhabditis elegans] hacd-1 gene33272 495 619 505 10553 9861 11717 26.577644 32.74658 26.696764543 556.274652012 512.23242598 626.252214426 8.128676061334e-111 4.29728773966113 up [I] Lipid transport and metabolism Molecular Function: 3-hydroxyacyl-CoA dehydrogenase activity (GO:0003857);; Biological Process: fatty acid metabolic process (GO:0006631);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00022|0|cel:CELE_R09B5.6|hacd-1; Protein HACD-1; K00022 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] (A) Fatty acid elongation (ko00062);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; Butanoate metabolism (ko00650);; Fatty acid metabolism (ko01212) [I] Lipid transport and metabolism 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain;; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain;; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus;; NADP oxidoreductase coenzyme F420-dependent;; NAD binding domain of 6-phosphogluconate dehydrogenase Protein HACD-1 {ECO:0000313|EMBL:CCD68882.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein HACD-1 [Caenorhabditis elegans] F49C12.4 gene18869 21 31 9 146 127 190 1.55465700000544 2.279363 0.669763 10.83743 9.623069 14.90197 2.39738839193856e-13 2.91264326141165 up -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein F49C12.4 {ECO:0000313|EMBL:CAA92509.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F49C12.4 [Caenorhabditis elegans] F08F3.4 gene34538 741 835 1040 256 204 197 45.7977 51.0128 62.9316 15.9543 12.8361 12.7341 2.05889330979128e-13 -2.00841756625589 down [MG] Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);; Biological Process: steroid biosynthetic process (GO:0006694);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; K15789|0|cel:CELE_F08F3.4|F08F3.4; Protein F08F3.4; K15789 threonine 3-dehydrogenase [EC:1.1.1.103] (A) Glycine, serine and threonine metabolism (ko00260) [R] General function prediction only NAD dependent epimerase/dehydratase family;; RmlD substrate binding domain;; Male sterility protein;; 3-beta hydroxysteroid dehydrogenase/isomerase family Protein F08F3.4 {ECO:0000313|EMBL:CCD65594.1} OS=Caenorhabditis elegans PE=4 SV=2 Q Secondary metabolites biosynthesis, transport and catabolism Protein F08F3.4 [Caenorhabditis elegans] abu-6 gene34466 386 370 379 156 163 129 12.48923 10.88978 11.32707 4.574728 4.288571 3.152328 3.37409140649411e-08 -1.35552514455745 down -- -- -- -- -- -- -- -- Protein ABU-6 {ECO:0000313|EMBL:CCD83355.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ABU-6 [Caenorhabditis elegans] ugt-17 gene36350 115 111 122 309 260 340 4.758472 4.72500439725 5.1360405423 13.610628 11.481564 16.229405 1.16713701023379e-07 1.37080431590372 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-17, isoform b {ECO:0000313|EMBL:CAN86590.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein UGT-17, isoform b [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_437 40 36 57 23 10 15 0.8079957981 0.7597345 1.179909 0.49992573 0.217087 0.35885447 0.00167822181255473 -1.48669900121715 down [C] Energy production and conversion Molecular Function: isocitrate lyase activity (GO:0004451);; Molecular Function: malate synthase activity (GO:0004474);; Biological Process: glyoxylate cycle (GO:0006097);; Biological Process: carboxylic acid metabolic process (GO:0019752);; -- -- [C] Energy production and conversion Isocitrate lyase family;; Phosphoenolpyruvate phosphomutase;; Malate synthase;; Isocitrate lyase family;; Malate synthase Malate synthase {ECO:0000256|RuleBase:RU000555} OS=Caenorhabditis japonica PE=3 SV=2 C Energy production and conversion isocitrate lyase [Agrobacterium tumefaciens] F46C5.1 gene7427 138 167 166 3133 2771 2822 54.31596 66.13338 70.21467 1241.869 1424.051 1240.086 2.95166051323736e-98 4.19729988358804 up -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EFO85988.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein F46C5.1 [Caenorhabditis elegans] fat-5 gene39723 555 504 265 2823 2443 2643 27.6399570000003 23.16446233 13.83662958895 130.762623 117.195751 116.479230000001 1.3119925133592e-43 2.56516563855864 up [I] Lipid transport and metabolism -- K00507|0|cel:CELE_W06D12.3|fat-5; Protein FAT-5; K00507 stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] (A) Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212) [I] Lipid transport and metabolism Fatty acid desaturase CBN-FAT-5 protein {ECO:0000313|EMBL:EGT49222.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 I Lipid transport and metabolism Protein FAT-5 [Caenorhabditis elegans] F52E10.4 gene46355 181 192 210 322 426 532 17.14886702198 15.7239187707 18.4473230124408 27.4893526174 34.0454198664674 42.9351606241371 0.00170492620394981 1.12104672365692 up -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EFP04132.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only hypothetical protein CRE_27587 [Caenorhabditis remanei] clec-21 gene4715 156 120 75 51 22 43 8.12413 6.12777 3.84507 2.62516 1.23466 2.30024 0.00800799151169028 -1.61189468358249 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain;; Chordopoxvirus A33R protein;; UL45 protein Protein CLEC-21 {ECO:0000313|EMBL:CCD63699.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-21 [Caenorhabditis elegans] cyp-32A1 gene35477 531 579 577 1147 1120 1194 19.8151693 22.7076069 22.74003607 45.88751 46.856587 50.50816 5.69796858516039e-07 1.02267208894076 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17954|0|cel:CELE_C26F1.2|cyp-32A1; Protein CYP-32A1; K17954 cytochrome P450, family 32 (A) -- [QI] Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism Cytochrome P450 Protein CYP-32A1 {ECO:0000313|EMBL:CCD65767.1} OS=Caenorhabditis elegans PE=3 SV=4 J Translation, ribosomal structure and biogenesis Protein CYP-32A1 [Caenorhabditis elegans] T07A5.1 gene12419 93 114 102 33 29 21 5.4923682605 6.66717487366 5.94019656464 1.9961083064 1.78100411399175 1.317090602 7.02806123124857e-08 -1.91080591102335 down -- -- -- -- -- -- -- LicD family Protein CBG24613 {ECO:0000313|EMBL:CAP21175.2} OS=Caenorhabditis briggsae PE=4 SV=2 R General function prediction only Protein T07A5.1 [Caenorhabditis elegans] col-71 gene5451 4574 4929 4910 1651 2115 1814 180.379 179.412 181.27 56.7117 70.3352 55.2928 8.9782510640813e-15 -1.38281637094113 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-71 {ECO:0000313|EMBL:CCD64720.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein COL-71 [Caenorhabditis elegans] F26F4.2 gene10658 54 84 80 35 35 26 9.84391 14.418 14.084 6.28096 6.84371 4.91463 0.00289353081838 -1.19725571291025 down -- -- -- -- -- -- -- -- Protein F26F4.2 {ECO:0000313|EMBL:CCD65750.1} OS=Caenorhabditis elegans PE=4 SV=2 Z Cytoskeleton Protein F26F4.2 [Caenorhabditis elegans] amt-1 gene42165 78 43 24 145 153 121 3.57857 1.99464 1.11929 6.60736 7.5064 5.88697 9.13252467367888e-06 1.5167439622798 up [P] Inorganic ion transport and metabolism Molecular Function: ammonium transmembrane transporter activity (GO:0008519);; Biological Process: ammonium transport (GO:0015696);; Cellular Component: membrane (GO:0016020);; K03320|0|cel:CELE_C05E11.4|amt-1; Protein AMT-1; K03320 ammonium transporter, Amt family (A) -- [P] Inorganic ion transport and metabolism Ammonium Transporter Family Protein CBR-AMT-1 {ECO:0000313|EMBL:CAP32998.1} OS=Caenorhabditis briggsae PE=4 SV=1 S Function unknown Protein AMT-1 [Caenorhabditis elegans] Y55B1AR.4 gene9507 35 55 56 19 25 18 2.14329 3.46558 3.50069 1.20053 1.60558 1.18734 0.006639318591752 -1.24929997042678 down -- -- -- -- -- -- -- -- Protein Y55B1AR.4 {ECO:0000313|EMBL:CCD73855.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein Y55B1AR.4 [Caenorhabditis elegans] ZK488.6 gene33050 84 80 97 40 43 38 3.32527 3.0869 3.72074 1.60366 1.7154 1.57413 0.00313107564481156 -1.1236033678326 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein ZK488.6 {ECO:0000313|EMBL:CCD71525.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein ZK488.6 [Caenorhabditis elegans] oac-15 gene39078 15 7 10 59 50 40 0.493515 0.22457585 0.322094 1.924842 1.7274 1.381641 1.73969642554649e-06 2.20327847995073 up [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- -- -- Acyltransferase family Protein OAC-15 {ECO:0000313|EMBL:CAB07360.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein OAC-15 [Caenorhabditis elegans] mpst-2 gene38459 7 9 13 51 25 38 0.531476 0.579368 0.73164 3.375263 1.90056 2.38899 0.00133879569186841 1.95917276005059 up [P] Inorganic ion transport and metabolism -- K01011|0|cel:CELE_H12D21.4|mpst-2; Protein MPST-2; K01011 thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] (A) Cysteine and methionine metabolism (ko00270);; Sulfur metabolism (ko00920);; Sulfur relay system (ko04122) [V] Defense mechanisms Rhodanese-like domain Sulfurtransferase {ECO:0000256|RuleBase:RU000507} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein MPST-2 [Caenorhabditis elegans] cyp-25A1 gene10293 76 90 88 454 489 485 3.2231 3.77576 3.68186 19.7879 21.9423 22.2927 7.12986220284964e-25 2.47725141036388 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-25A1 {ECO:0000313|EMBL:CAA91268.3} OS=Caenorhabditis elegans PE=3 SV=3 G Carbohydrate transport and metabolism Protein CYP-25A1 [Caenorhabditis elegans] npa-1 gene35186 16157 13874 9307 25559 29468 31522 214.7748 196.5427 130.1598 353.9894 386.9979 442.419 1.04378488335756e-07 1.12429804653933 up -- -- -- -- -- -- -- Rab3 GTPase-activating protein catalytic subunit;; Phage uncharacterised protein (Phage_XkdX);; Protein of unknown function (DUF3775);; Drug resistance and apoptosis regulator;; Anti-Sigma Factor A;; Maintenance of mitochondrial structure and function Protein NPA-1, isoform a {ECO:0000313|EMBL:CCD70075.1} OS=Caenorhabditis elegans PE=2 SV=1 K Transcription Protein NPA-1, isoform a [Caenorhabditis elegans] ant-1.4 gene18579 162 200 181 71 54 71 13.6625 16.4862 14.9327 5.94852 4.58247 6.09322 5.13657714435178e-07 -1.48410669161619 down -- -- -- K05863|0|cel:CELE_T01B11.4|ant-1.4; Protein ANT-1.4; K05863 solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31 (A) Calcium signaling pathway (ko04020) [C] Energy production and conversion Mitochondrial carrier protein Protein ANT-1.4 {ECO:0000313|EMBL:CCD65922.1} OS=Caenorhabditis elegans PE=2 SV=1 S Function unknown Protein ANT-1.4 [Caenorhabditis elegans] F58E6.6 gene36218 149 145 215 77 73 99 6.96313 6.27671 10.68917 4.16058800003558 3.969463695 4.15833 0.00309070042483555 -1.04622245921643 down -- -- -- -- -- -- -- -- Protein F58E6.6 {ECO:0000313|EMBL:CAA94776.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein F58E6.6 [Caenorhabditis elegans] kmo-1 gene37330 565 557 563 221 228 207 24.24486 23.77803 23.67722 9.5237008 10.15533 8.9427525 1.18433074342481e-09 -1.37521757507878 down -- -- Molecular Function: FAD binding (GO:0071949);; K00486|0|cel:CELE_R07B7.5|kmo-1; Protein KMO-1; K00486 kynurenine 3-monooxygenase [EC:1.14.13.9] (A) Tryptophan metabolism (ko00380) [CR] Energy production and conversion;; General function prediction only FAD binding domain;; Squalene epoxidase;; Pyridine nucleotide-disulphide oxidoreductase Kynurenine 3-monooxygenase {ECO:0000256|HAMAP-Rule:MF_03018} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 S Function unknown Protein KMO-1 [Caenorhabditis elegans] gpx-5 gene44063 2752 3071 2107 6124 6192 6932 243.3541 258.75796 182.54271 509.22828 505.66761 553.97659 1.85500541994813e-12 1.26609677664353 up [O] Posttranslational modification, protein turnover, chaperones Molecular Function: glutathione peroxidase activity (GO:0004602);; Biological Process: response to oxidative stress (GO:0006979);; Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00432|1.47027e-158|cel:CELE_C11E4.1|gpx-5; Protein GPX-5; K00432 glutathione peroxidase [EC:1.11.1.9] (A) Glutathione metabolism (ko00480);; Arachidonic acid metabolism (ko00590) [O] Posttranslational modification, protein turnover, chaperones Glutathione peroxidase;; AhpC/TSA family Glutathione peroxidase {ECO:0000256|RuleBase:RU000499} OS=Caenorhabditis elegans PE=3 SV=3 T Signal transduction mechanisms Protein GPX-5 [Caenorhabditis elegans] R12H7.4 gene45281 20 16 7 42 37 36 1.31356 1.04217 0.467097 2.74977 2.5915 2.46033 0.00509069649484215 1.40574062438761 up -- -- -- -- -- -- -- -- Protein R12H7.4 {ECO:0000313|EMBL:CAA90634.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein R12H7.4 [Caenorhabditis elegans] scl-2 gene20357 3012 2535 2603 8183 7308 7814 376.3294 298.3066 314.10042 988.06494 1001.964 1026.1479 3.22133845441676e-17 1.50126818447361 up [S] Function unknown -- -- -- [S] Function unknown Cysteine-rich secretory protein family Protein SCL-2, isoform a {ECO:0000313|EMBL:CAA94344.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein SCL-2, isoform a [Caenorhabditis elegans] pccb-1 gene41609 7200 6808 6832 13607 14588 14513 253.769306455034 236.50513981711 238.783333331 472.986091649394 512.558114974871 520.247042261013 5.3938790033666e-08 1.0210683465837 up [I] Lipid transport and metabolism -- K01966|0|cel:CELE_F52E4.1|pccb-1; Protein PCCB-1, isoform A; K01966 propionyl-CoA carboxylase beta chain [EC:6.4.1.3] (A) Valine, leucine and isoleucine degradation (ko00280);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640) [EI] Amino acid transport and metabolism;; Lipid transport and metabolism Carboxyl transferase domain Protein PCCB-1, isoform a {ECO:0000313|EMBL:CCD66477.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein PCCB-1, isoform a [Caenorhabditis elegans] F36H1.3 gene19587 46 81 78 18 35 22 1.56598 2.75878 2.69908 0.639298 1.22004 0.819186 0.00278134086327935 -1.46356511231495 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase Protein F36H1.3 {ECO:0000313|EMBL:CAA92995.3} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein F36H1.3 [Caenorhabditis elegans] pqn-27 gene8917 3682 3486 3346 6552 7497 8506 266.9464064 215.45377 224.2630705 467.918625000001 571.375878 663.379968 2.88511201548632e-09 1.08740437315791 up -- -- -- K14322|0|cel:CELE_E01G4.4|pqn-27; Protein PQN-27, isoform C; K14322 polyadenylate-binding protein-interacting protein 1 (A) RNA transport (ko03013) -- -- -- Protein PQN-27, isoform a {ECO:0000313|EMBL:CAB05716.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein PQN-27, isoform a [Caenorhabditis elegans] msrp-2 gene1396 99 95 128 37 36 49 183.527 156.273 221.808 71.4382 101.55 119.242 4.90639878762857e-05 -1.41464056030848 down -- -- -- -- -- -- -- -- Protein ZK484.5 {ECO:0000313|EMBL:CCD65802.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZK484.5 [Caenorhabditis elegans] F41E6.5 gene35773 313 293 335 1211 1064 1194 19.510614 18.75493 21.32036 78.52522 71.04541 82.80004 9.83823832075833e-21 1.86766394442266 up [C] Energy production and conversion Molecular Function: catalytic activity (GO:0003824);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K11517|0|cbr:CBG01477|Hypothetical protein CBG01477; K11517 (S)-2-hydroxy-acid oxidase [EC:1.1.3.15] (A) Glyoxylate and dicarboxylate metabolism (ko00630);; Peroxisome (ko04146) [C] Energy production and conversion FMN-dependent dehydrogenase;; Nitronate monooxygenase;; IMP dehydrogenase / GMP reductase domain;; Thiazole biosynthesis protein ThiG Protein F41E6.5, isoform b {ECO:0000313|EMBL:CCD64095.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein F41E6.5, isoform b [Caenorhabditis elegans] cpt-5 gene38060 637 583 495 1373 1224 1309 16.9025005467 15.834616 13.224629 37.6134 33.81921 38.26244 3.48893495028351e-09 1.17338612028164 up -- -- Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; -- -- [I] Lipid transport and metabolism Choline/Carnitine o-acyltransferase Protein CPT-5 {ECO:0000313|EMBL:CAB02911.3} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CPT-5 [Caenorhabditis elegans] F22B5.4 gene7295 289 269 220 1556 1384 1533 59.6438 49.8176 39.1193 294.831 272.392 289.798 6.14184119739101e-37 2.50942119693274 up -- -- -- -- -- -- -- -- Protein F22B5.4 {ECO:0000313|EMBL:CAA90356.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F22B5.4 [Caenorhabditis elegans] tre-5 gene4213 432 416 538 189 197 190 12.5783 12.1604 15.6823 5.63649 5.91838 5.96231 5.61569477246835e-08 -1.28143377506304 down [G] Carbohydrate transport and metabolism Molecular Function: alpha,alpha-trehalase activity (GO:0004555);; Biological Process: trehalose metabolic process (GO:0005991);; K01194|0|cel:CELE_C23H3.7|tre-5; Protein TRE-5; K01194 alpha,alpha-trehalase [EC:3.2.1.28] (A) Starch and sucrose metabolism (ko00500) [G] Carbohydrate transport and metabolism Trehalase;; Amylo-alpha-1,6-glucosidase Trehalase {ECO:0000256|RuleBase:RU361180} OS=Caenorhabditis elegans PE=2 SV=1 K Transcription Protein TRE-5 [Caenorhabditis elegans] msp-79 gene19061 149 215 237 91 89 119 74.8916 96.6497 112.771 43.4269 50.7899 62.3364 0.00282531364643829 -1.02101795965339 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein MSP-77 [Caenorhabditis elegans] cyp-35A4 gene34129 71 141 74 25 7 25 3.24905 6.59046 3.38698 1.21917 0.369273 1.32946 0.00283044267051989 -2.34000561426819 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17957|0|cel:CELE_C49G7.8|cyp-35A4; Protein CYP-35A4; K17957 cytochrome P450, family 35 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-35A4 {ECO:0000313|EMBL:CCD67691.1} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein CYP-35A4 [Caenorhabditis elegans] col-139 gene34295 5450 8258 8658 2349 2305 2320 276.10267 401.84827178 421.00326 112.09727 104.20642333 105.28749 1.12672660637918e-06 -1.69523178004533 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-139 {ECO:0000313|EMBL:CCD71018.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein COL-139 [Caenorhabditis elegans] Y110A2AL.2 gene5185 39 28 27 68 106 97 1.244081 0.880695000015238 0.822878000392635 2.019879 3.060694264 2.694533 4.26696128905714e-05 1.51388930919684 up -- -- -- -- -- -- -- CC domain Protein Y110A2AL.2 {ECO:0000313|EMBL:CCD72971.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein Y110A2AL.2 [Caenorhabditis elegans] asp-16 gene40150 61 50 26 268 270 305 3.39896 2.64283 1.40578 14.1999 15.1236 16.2492 1.75286315759724e-21 2.60814982640559 up -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease;; Xylanase inhibitor N-terminal Protein ASP-16 {ECO:0000313|EMBL:CAD31820.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein ASP-16 [Caenorhabditis elegans] pck-1 gene9394 11572 9803 10296 24983 27180 27904 289.019204 235.986376084325 254.88775118 584.26908482 635.36686643 647.577100000005 4.84140610825741e-12 1.32385254495987 up [C] Energy production and conversion Molecular Function: phosphoenolpyruvate carboxykinase activity (GO:0004611);; Biological Process: gluconeogenesis (GO:0006094);; K01596|0|cbr:CBG00466|Hypothetical protein CBG00466; K01596 phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] (A) Glycolysis / Gluconeogenesis (ko00010);; Citrate cycle (TCA cycle) (ko00020);; Pyruvate metabolism (ko00620);; FoxO signaling pathway (ko04068) [C] Energy production and conversion Phosphoenolpyruvate carboxykinase Protein PCK-1, isoform a {ECO:0000313|EMBL:CCD71753.1} OS=Caenorhabditis elegans PE=3 SV=2 W Extracellular structures Protein PCK-1, isoform a [Caenorhabditis elegans] col-142 gene35088 8539 8327 10957 4527 4029 4333 372.6366 343.9593 462.8338 182.3993 156.7233 167.841 1.18643283053809e-07 -1.1250017340697 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein CBR-COL-142 {ECO:0000313|EMBL:CAP36341.2} OS=Caenorhabditis briggsae PE=4 SV=2 W Extracellular structures Protein CBR-COL-142 [Caenorhabditis briggsae] nas-20 gene37043 179 320 368 87 83 86 10.77024 19.32106 21.22327 5.34964 5.25249 5.73711 0.00144478076176711 -1.77401556334816 down -- -- Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; K08076|0|cel:CELE_T11F9.3|nas-20; Protein NAS-20; K08076 astacin [EC:3.4.24.21] (A) -- [O] Posttranslational modification, protein turnover, chaperones Astacin (Peptidase family M12A) Metalloendopeptidase {ECO:0000256|RuleBase:RU361183} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 S Function unknown Protein NAS-20 [Caenorhabditis elegans] F46A8.11 gene3076 152 204 122 264 352 370 6.226368354 9.987831082 4.1860697147 11.3172451 16.3392683 14.7546057 0.000462001820612047 1.03224890970943 up -- -- -- -- -- -- -- -- Protein F46A8.11 {ECO:0000313|EMBL:CCE71367.2} OS=Caenorhabditis elegans PE=4 SV=1 M Cell wall/membrane/envelope biogenesis Protein F46A8.11 [Caenorhabditis elegans] clec-48 gene39844 628 497 370 1084 1099 1325 43.95249 33.0182 24.85781 72.04749 74.27185 86.1642 1.22675689024396e-08 1.21685392641937 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-48 {ECO:0000313|EMBL:CAB03881.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-48 [Caenorhabditis elegans] dhs-2 gene1175 220 212 195 569 613 750 15.3813712197 14.1911574624792 12.8758008317 37.963499624 43.1719861956331 53.539392246 2.61560276664425e-13 1.60989482351946 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- -- -- [QR] Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase Protein DHS-2, isoform a {ECO:0000313|EMBL:CCD65438.1} OS=Caenorhabditis elegans PE=3 SV=2 S Function unknown Protein DHS-2, isoform a [Caenorhabditis elegans] mul-1 gene14224 1234 1482 1081 540 426 505 136.4716 138.903 106.4465 52.01915 49.1824 53.1503 2.13599971726887e-10 -1.38173789911808 down -- -- -- -- -- -- -- ShK domain-like Protein MUL-1 {ECO:0000313|EMBL:CCD66748.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F49F1.6 [Caenorhabditis elegans] F59E11.7 gene35924 250 318 205 573 550 646 25.2033959595973 29.4936430072297 17.344583616 63.28975092457 58.03557043637 67.0828013883615 1.8107224448488e-07 1.18138792641282 up -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein F59E11.7, isoform a {ECO:0000313|EMBL:CCD72136.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F59E11.7, isoform a [Caenorhabditis elegans] fbxb-72 gene33103 29 21 45 91 91 95 2.29672 1.63866 3.4464 7.18785 7.36524 7.97627 3.121347758261e-05 1.52813386307049 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- F-box associated Protein FBXB-72 {ECO:0000313|EMBL:CCD63257.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein FBXB-72 [Caenorhabditis elegans] K06H6.2 gene33047 423 390 419 150 125 118 28.6486 24.8996 27.2782 9.83828 8.46599 7.88222 4.67445909526472e-12 -1.66319630947135 down -- -- -- -- -- -- -- Methyltransferase domain;; Methyltransferase FkbM domain Protein K06H6.2 {ECO:0000313|EMBL:CCD64473.1} OS=Caenorhabditis elegans PE=4 SV=1 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein K06H6.2 [Caenorhabditis elegans] chil-5 gene7807 74 76 37 160 126 190 2.751493 2.0836509 1.479687 5.191789 3.83757391136 7.62235 0.000197158955537119 1.33500797162129 up [G] Carbohydrate transport and metabolism Biological Process: carbohydrate metabolic process (GO:0005975);; -- -- [G] Carbohydrate transport and metabolism Glycosyl hydrolases family 18 Protein CHIL-5 {ECO:0000313|EMBL:CAA91148.1} OS=Caenorhabditis elegans PE=3 SV=1 G Carbohydrate transport and metabolism Protein C08H9.11 [Caenorhabditis elegans] C14C6.6 gene33032 170 160 161 75 84 48 5.85495 5.31932 5.311971 2.504179 2.745499 1.551272 3.98982508922535e-05 -1.26064428619852 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein C14C6.6 {ECO:0000313|EMBL:CCD64462.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein C14C6.6 [Caenorhabditis elegans] F58G1.3 gene8815 75 94 112 38 36 52 4.24951 5.29758 6.46223 2.21464 2.1653 3.21881 0.00150904227393512 -1.17116879090663 down [T] Signal transduction mechanisms Molecular Function: hydrolase activity (GO:0016787);; K01090|0|cel:CELE_F58G1.3|F58G1.3; Protein F58G1.3; K01090 protein phosphatase [EC:3.1.3.16] (A) -- [TR] Signal transduction mechanisms;; General function prediction only Calcineurin-like phosphoesterase Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein F58G1.3 [Caenorhabditis elegans] clec-2 gene5237 3467 4233 1892 377 235 222 167.758 195.789 88.632 17.5069 11.4639 10.6818 8.43373258991866e-07 -3.53734666661957 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain Protein CLEC-2 {ECO:0000313|EMBL:CCD61973.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CLEC-2 [Caenorhabditis elegans] nspc-9 gene45016 260 243 289 90 64 63 421.1408 321.7978 395.132 130.4074 151.2797 129.3475 2.13614425988792e-12 -1.88307135091588 down -- -- -- -- -- -- -- -- Protein NSPC-9 {ECO:0000313|EMBL:CAA92174.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein NSPC-9 [Caenorhabditis elegans] col-62 gene1862 406 500 623 134 129 140 15.14718 18.97808 23.36655 5.00495 4.084008 5.05485 4.24105624544313e-09 -1.93818350687684 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-62 {ECO:0000313|EMBL:CAB01958.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-62 [Caenorhabditis elegans] C30H6.12 gene32841 25 31 42 266 256 324 3.466662 4.000709359 5.897584 33.688337252 35.74137 46.77378 1.12758691783023e-27 3.09535863462005 up -- -- -- -- -- -- -- -- Protein C30H6.12, isoform a {ECO:0000313|EMBL:CCG28140.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein C30H6.12, isoform a [Caenorhabditis elegans] ZK418.11 gene11328 13 10 6 24 24 38 0.799145107366 0.611590453908 0.387412100764 1.52107320768 1.750954 2.5998045796 0.00539249322414102 1.5552036708178 up -- -- Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; -- -- -- -- Ligand-binding domain of nuclear hormone receptor Protein ZK418.11 {ECO:0000313|EMBL:CCD61632.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZK418.11 [Caenorhabditis elegans] K07A1.4 gene2531 56 46 69 16 20 26 5.17619 4.16972 6.30625 1.53866 2.00486 2.70126 0.000624231238257704 -1.47801590484945 down -- -- -- -- -- -- -- -- Protein K07A1.4 {ECO:0000313|EMBL:CAB03166.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein K07A1.4 [Caenorhabditis elegans] K10G4.5 gene39550 121 90 70 205 188 261 3.00346207 2.219172325 1.667302 5.136648 4.746905 6.60393700001016 4.87414957683681e-05 1.20491772647687 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein K10G4.5 {ECO:0000313|EMBL:CAB07255.4} OS=Caenorhabditis elegans PE=4 SV=4 R General function prediction only Protein K10G4.5 [Caenorhabditis elegans] clec-75 gene14172 165 181 133 360 490 432 7.8672804889 4.8471123122 3.6683423131 11.82394156 18.4457141262 18.76873396 4.09837436968699e-09 1.40723684318015 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-75, isoform b {ECO:0000313|EMBL:CCD71971.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-75, isoform b [Caenorhabditis elegans] Y49E10.29 gene12926 114 134 140 71 64 44 2.91883 3.23342 3.33788 1.608026 1.32171 0.876311 0.000693738133979442 -1.13082653296115 down -- -- -- -- -- -- -- -- Protein Y49E10.29 {ECO:0000313|EMBL:CAM33505.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein Y49E10.29 [Caenorhabditis elegans] F22F7.2 gene33465 2505 2754 2512 5543 5640 5466 91.991004225 96.487714666 91.244140982 191.569295898 194.482515821 192.830694256 2.51392637935543e-09 1.08535853219667 up [S] Function unknown Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [S] Function unknown Saccharopine dehydrogenase Protein F22F7.2 {ECO:0000313|EMBL:CCD67441.1} OS=Caenorhabditis elegans PE=4 SV=2 G Carbohydrate transport and metabolism Protein F22F7.2 [Caenorhabditis elegans] fil-1 gene38493 151 160 148 71 63 54 12.063 12.8153 11.8184 5.74836 5.37894 4.65106 3.13207322804686e-05 -1.30213753339497 down -- -- Molecular Function: hydrolase activity (GO:0016787);; -- -- -- -- Lipase (class 2) Protein FIL-1 {ECO:0000313|EMBL:CAB01664.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein FIL-1 [Caenorhabditis elegans] D1054.18 gene36672 39 49 60 106 82 124 12.8125100000002 32.20237 5.3280314 9.91638474487 7.8035614016751 866.792700000091 0.00329629351590115 1.06153319958112 up -- -- -- -- -- -- -- -- Protein D1054.18, isoform a {ECO:0000313|EMBL:CAQ76464.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein D1054.18, isoform a [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_617 65 50 60 20 21 27 3.27692 2.49734 2.98921 1.02903 1.13848 1.49748 0.00133451244288796 -1.37805837434561 down -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EFP12628.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only -- F55A4.7 gene40972 15 19 17 42 44 59 6.03383 7.00081 6.70574 16.5347 20.1326 25.3826 0.00116547626974068 1.49417060902238 up -- -- -- -- -- -- -- Calponin family repeat Protein F55A4.7 {ECO:0000313|EMBL:CCD62877.1} OS=Caenorhabditis elegans PE=4 SV=4 KU Transcription;; Intracellular trafficking, secretion, and vesicular transport Protein F55A4.7 [Caenorhabditis elegans] dhs-9 gene10795 1950 1758 1555 3963 3237 4051 123.683014842 108.16004 98.435744293 248.21887 207.47698925 262.602521442 3.63485611647611e-09 1.08192905270825 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- K11163|0|cel:CELE_Y32H12A.3|dhs-9; Protein DHS-9; K11163 dehydrogenase/reductase SDR family member 1 [EC:1.1.-.-] (A) -- [R] General function prediction only short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase Protein DHS-9 {ECO:0000313|EMBL:CCD73961.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein DHS-9 [Caenorhabditis elegans] Y39B6A.27 gene40148 194 220 156 518 461 635 9.18838 10.2321 7.23981 23.8111 21.4558 28.6921 1.44288125703966e-09 1.4883530484545 up -- -- -- -- -- [S] Function unknown Ion channel regulatory protein UNC-93;; Major Facilitator Superfamily Protein Y39B6A.27 {ECO:0000313|EMBL:CAD31837.2} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein Y39B6A.27 [Caenorhabditis elegans] W08E12.2 gene13966 44 58 97 144 144 150 33.3997 39.71 70.9147 106.792 149.382 131.051 0.000487088609362371 1.12310841198653 up -- -- -- -- -- -- -- -- Protein W08E12.2 {ECO:0000313|EMBL:CCD74010.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein W08E12.2 [Caenorhabditis elegans] F56C3.9 gene41042 167 171 97 520 481 633 24.444986 23.36403890406 13.49629185806 73.81454 72.946643 95.25653 7.12464011835665e-15 1.8963239868886 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- BTB/POZ domain Protein F56C3.9 {ECO:0000313|EMBL:CCD69814.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein F56C3.9 [Caenorhabditis elegans] F25D1.5 gene36545 157 241 153 87 64 93 14.1285 22.0463 13.9084 8.0787 5.9442 8.80189 0.00353492998875018 -1.18820327795282 down [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- -- -- [R] General function prediction only Enoyl-(Acyl carrier protein) reductase;; short chain dehydrogenase;; KR domain Protein F25D1.5 {ECO:0000313|EMBL:CAA98264.1} OS=Caenorhabditis elegans PE=1 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein F25D1.5 [Caenorhabditis elegans] F56A4.3 gene33579 1949 1195 1289 782 503 566 261.895132025169 128.028247842 170.14060735502 98.0248 66.88658 73.7893143470091 0.00395018442654871 -1.27545212859325 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain Protein F56A4.3 {ECO:0000313|EMBL:CCD62313.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F56A4.3 [Caenorhabditis elegans] W03D8.8 gene525 58 45 28 150 150 210 2.493594 1.758084 1.027902 5.94018 5.88199 7.76338 2.87211236990387e-08 1.94766185695243 up [R] General function prediction only -- -- -- -- -- BAAT / Acyl-CoA thioester hydrolase C terminal;; Acyl-CoA thioester hydrolase/BAAT N-terminal region;; Dienelactone hydrolase family Protein W03D8.8 {ECO:0000313|EMBL:CCD73381.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein W03D8.8 [Caenorhabditis elegans] R01H2.2 gene11309 53 40 56 14 21 29 2.68693 1.90422 2.68929 0.699536 1.20815 1.55096 0.00702873233827867 -1.23308473148373 down -- -- -- -- -- -- -- Domain of unknown function (DUF316) Protein R01H2.2 {ECO:0000313|EMBL:CCD69283.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein R01H2.2 [Caenorhabditis elegans] C02F12.5 gene41809 215 226 240 598 426 422 48.05216 47.41121 52.8214 134.2029 117.2107 109.8432 0.000124567366824887 1.07139188218069 up -- -- Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; -- -- [O] Posttranslational modification, protein turnover, chaperones Kunitz/Bovine pancreatic trypsin inhibitor domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT30633.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein C02F12.5 [Caenorhabditis elegans] C08E3.1 gene4737 70 59 21 151 94 164 289.3911 208.9573 87.2552 789.849 588.823 1110.2 0.0061531464844104 1.43399368656286 up -- -- -- -- -- -- -- -- Protein C08E3.13 {ECO:0000313|EMBL:CCD63678.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C08E3.1 [Caenorhabditis elegans] col-110 gene14405 189 202 231 36 48 50 11.2345 11.631 13.5587 2.09287 2.957 2.94897 1.50722728898862e-14 -2.22847558657887 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-110 {ECO:0000313|EMBL:CCD69718.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-110 [Caenorhabditis elegans] C05D12.2 gene8320 285 388 325 670 699 804 4.6442181 6.3470765178 5.197926715 11.141006221 11.56723236 14.111057032 4.08505871894644e-07 1.10927133082684 up -- -- -- -- -- -- -- -- Protein C05D12.2 {ECO:0000313|EMBL:CAA90754.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C05D12.2 [Caenorhabditis elegans] Y37A1B.5 gene21938 7571 8455 7829 34398 31364 38419 323.399044403462 362.513390708804 334.629492751117 1504.69496062002 1398.706195 1796.25506695875 2.5439580939949e-28 2.11286587656045 up -- -- Molecular Function: selenium binding (GO:0008430);; K17285|0|cel:CELE_Y37A1B.5|Y37A1B.5; Protein Y37A1B.5, isoform A; K17285 selenium-binding protein 1 (A) -- [P] Inorganic ion transport and metabolism 56kDa selenium binding protein (SBP56);; Lactonase, 7-bladed beta-propeller Protein Y37A1B.5, isoform a {ECO:0000313|EMBL:CAA19490.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein Y37A1B.5, isoform a [Caenorhabditis elegans] Y116F11B.6 gene40421 27 27 20 62 46 61 1.707716 1.749487 1.22827 3.83209 2.847593 3.98778 0.00763499493869457 1.17754466837218 up -- -- -- -- -- -- -- -- Protein Y116F11B.6 {ECO:0000313|EMBL:CAB81974.2} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein Y116F11B.6 [Caenorhabditis elegans] C32C4.3 gene36585 30 40 36 13 12 8 2.387740241 3.08958 2.76989000005763 1.061915 1.03807000000004 0.701492 0.000943274049614278 -1.69782824020038 down -- -- -- -- -- -- -- -- Protein C32C4.3, isoform c {ECO:0000313|EMBL:CBL43416.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein C32C4.3, isoform c [Caenorhabditis elegans] clec-85 gene13870 2961 3962 2671 1209 1018 1226 257.25120504 331.291210298 223.915191967 100.746306253 89.9923552202 105.4857414 5.78722935989786e-07 -1.48754351776487 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-85, isoform a {ECO:0000313|EMBL:CCD83493.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-85 [Caenorhabditis elegans] col-60 gene1761 1105 1155 1230 360 374 319 73.21463 75.1965 81.05351 23.673733 24.665882922 21.35545355 2.15895968805557e-18 -1.74306612622169 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-60 {ECO:0000313|EMBL:CAA95812.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein COL-60 [Caenorhabditis elegans] tag-10 gene8956 408 360 337 1418 1396 1549 15.196511905 13.0720674731078 12.5521455992315 50.277762 50.29036126 55.0703688 4.56608162276658e-24 1.96721463562282 up [U] Intracellular trafficking, secretion, and vesicular transport -- -- -- -- -- WD40-like Beta Propeller Repeat Protein TAG-10, isoform a {ECO:0000313|EMBL:CAB05698.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein TAG-10, isoform a [Caenorhabditis elegans] pitr-4 gene36179 76 88 45 25 12 28 3.28088 3.83852 1.97116 1.1313 0.569446 1.35973 0.00224310382123109 -1.69818990677162 down [P] Inorganic ion transport and metabolism Molecular Function: inorganic phosphate transmembrane transporter activity (GO:0005315);; Biological Process: phosphate ion transport (GO:0006817);; Cellular Component: membrane (GO:0016020);; -- -- [P] Inorganic ion transport and metabolism Phosphate transporter family Protein PITR-4 {ECO:0000313|EMBL:CAB11776.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein PITR-4 [Caenorhabditis elegans] F57H12.6 gene18401 1231 1267 1109 621 441 460 177.075 176.275 156.653 89.5593 64.6668 68.9552 2.91658940625364e-10 -1.25937381040173 down -- -- -- -- -- -- -- -- Protein F57H12.6 {ECO:0000313|EMBL:CCD69772.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F57H12.6 [Caenorhabditis elegans] sams-5 gene17284 456 569 594 261 244 223 21.369308 26.810936 28.765043 12.76565129005 11.9227886348 11.00854740916 3.79362236196248e-07 -1.16740395313793 down [H] Coenzyme transport and metabolism Molecular Function: methionine adenosyltransferase activity (GO:0004478);; Biological Process: S-adenosylmethionine biosynthetic process (GO:0006556);; K00789|0|cbr:CBG19844|Hypothetical protein CBG19844; K00789 S-adenosylmethionine synthetase [EC:2.5.1.6] (A) Cysteine and methionine metabolism (ko00270);; Biosynthesis of amino acids (ko01230) [H] Coenzyme transport and metabolism S-adenosylmethionine synthetase, C-terminal domain;; S-adenosylmethionine synthetase, central domain;; S-adenosylmethionine synthetase, N-terminal domain S-adenosylmethionine synthase {ECO:0000256|RuleBase:RU000541} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 S Function unknown Protein SAMS-5, isoform a [Caenorhabditis elegans] cyp-25A2 gene10294 424 395 308 1552 1396 1734 18.1189 16.7845 13.1406 68.3846 62.6516 81.3046 4.28907576444548e-26 2.04090032952487 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-25A2 {ECO:0000313|EMBL:CAA91267.2} OS=Caenorhabditis elegans PE=3 SV=2 G Carbohydrate transport and metabolism Protein CYP-25A2 [Caenorhabditis elegans] gst-25 gene262 47 46 34 146 102 129 6.00176 5.58424 4.30007 17.7558 13.6916 16.2471 2.74309298112145e-06 1.55564655062164 up -- -- -- K00799|2.2403e-104|cbr:CBG06825|Cbr-gst-1; C. briggsae CBR-GST-1 protein; K00799 glutathione S-transferase [EC:2.5.1.18] (A) Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982) [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein GST-25 {ECO:0000313|EMBL:CCD70778.1} OS=Caenorhabditis elegans PE=3 SV=1 U Intracellular trafficking, secretion, and vesicular transport GST-25 [Caenorhabditis elegans] nlp-80 gene36794 637 850 379 1284 1097 1630 1744.101 1940.835 1073.9637 3146.498 3216.584 4078.127 0.00470931008371029 1.09174285512585 up -- -- -- -- -- -- -- -- Protein T04C12.3 {ECO:0000313|EMBL:CAB04677.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein T04C12.3 [Caenorhabditis elegans] gst-4 gene19246 4194 3692 3507 10718 8400 10524 277.131030284 227.492200000002 226.618000000071 738.333126 585.302768 722.244334 3.89286379483815e-14 1.36509954582621 up [O] Posttranslational modification, protein turnover, chaperones Molecular Function: protein binding (GO:0005515);; K00799|6.36308e-150|cel:CELE_K08F4.7|gst-4; Protein GST-4; K00799 glutathione S-transferase [EC:2.5.1.18] (A) Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982) [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein CBR-GST-4 {ECO:0000313|EMBL:CAP24347.1} OS=Caenorhabditis briggsae PE=3 SV=1 S Function unknown Protein GST-4 [Caenorhabditis elegans] cth-1 gene39024 223 193 223 519 464 413 11.0988786850164 9.54064089900071 11.2959927 22.4291006517004 18.2735700000003 18.23262815 3.01523620466243e-06 1.11251309386607 up [E] Amino acid transport and metabolism Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; K01758|0|cel:CELE_F22B8.6|cth-1; Protein CTH-1, isoform B; K01758 cystathionine gamma-lyase [EC:4.4.1.1] (A) Glycine, serine and threonine metabolism (ko00260);; Cysteine and methionine metabolism (ko00270);; Selenocompound metabolism (ko00450);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Cys/Met metabolism PLP-dependent enzyme;; Aminotransferase class I and II;; Methionine gamma-lyase;; DegT/DnrJ/EryC1/StrS aminotransferase family;; Aminotransferase class-V Protein CTH-1, isoform a {ECO:0000313|EMBL:CAB05492.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein CTH-1, isoform a [Caenorhabditis elegans] fbxa-182 gene5029 449 356 352 722 894 1113 11.2011109320834 8.81976793480024 8.531675994214 19.4001783156 19.91873420684 29.66872787364 0.000117739016938925 1.2242892095968 up -- -- -- -- -- -- -- FTH domain Protein FBXA-182 {ECO:0000313|EMBL:CCD70284.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein FBXA-182 [Caenorhabditis elegans] F26H9.5 gene2399 2948 3254 2903 17961 16943 21051 152.42238 167.593581 148.92897 934.385801 892.482776 1133.11647 4.90425165276644e-46 2.60581869358293 up [HE] Coenzyme transport and metabolism;; Amino acid transport and metabolism -- K00831|0|cel:CELE_F26H9.5|F26H9.5; Protein F26H9.5; K00831 phosphoserine aminotransferase [EC:2.6.1.52] (A) Glycine, serine and threonine metabolism (ko00260);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [HE] Coenzyme transport and metabolism;; Amino acid transport and metabolism Aminotransferase class-V Phosphoserine aminotransferase {ECO:0000256|RuleBase:RU004505} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein F26H9.5 [Caenorhabditis elegans] irg-4 gene20169 13352 18326 8129 3875 2543 2681 929.649 1269.485 556.4788 274.224 182.0703 199.1075 0.00129302224240569 -2.1424516548219 down -- -- -- -- -- -- -- CUB-like domain Protein F08G5.6 {ECO:0000313|EMBL:CAA94586.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F08G5.6 [Caenorhabditis elegans] F07G6.10 gene41140 51 79 90 26 25 19 73.2072 99.3245 118.516 38.6121 53.9696 35.8005 0.000166149552639753 -1.66658176483536 down -- -- -- -- -- -- -- -- Protein F07G6.10 {ECO:0000313|EMBL:CCD66892.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F07G6.10 [Caenorhabditis elegans] Y73C8C.3 gene33808 32 29 73 195 203 256 1.008670901 0.689604763683731 1.5366009 11.1974703231 10.5478598 15.066152012526 1.81929263166696e-13 2.27132403182185 up -- -- -- -- -- -- -- -- Protein Y73C8C.3 {ECO:0000313|EMBL:CCD67817.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein Y73C8C.3 [Caenorhabditis elegans] T10B5.8 gene33384 145 164 155 65 61 90 6.37915 6.93472 6.624422 2.739306 2.029634 3.70484 0.000399917450283241 -1.11669818272799 down [C] Energy production and conversion Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [CR] Energy production and conversion;; General function prediction only NADH:flavin oxidoreductase / NADH oxidase family Protein T10B5.8 {ECO:0000313|EMBL:CCD74228.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T10B5.8 [Caenorhabditis elegans] H20J04.1 gene5715 77 80 96 34 27 38 1.74262 1.84538 2.17938 0.825482 0.662317 0.988828 0.000307616611234354 -1.36816919391722 down -- -- -- -- -- -- -- Domain of unknown function Protein H20J04.1 {ECO:0000313|EMBL:CCD61676.1} OS=Caenorhabditis elegans PE=4 SV=1 B Chromatin structure and dynamics Protein H20J04.1 [Caenorhabditis elegans] icmt-1 gene1052 282 318 388 129 118 175 20.07823 21.05737 25.67362 8.27999 8.20088 10.65915 1.58229506302894e-06 -1.24143852991599 down [O] Posttranslational modification, protein turnover, chaperones Molecular Function: protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity (GO:0004671);; Biological Process: C-terminal protein methylation (GO:0006481);; Cellular Component: integral component of membrane (GO:0016021);; K00587|0|cel:CELE_F21F3.3|F21F3.3; Protein F21F3.3; K00587 protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100] (A) Terpenoid backbone biosynthesis (ko00900) [O] Posttranslational modification, protein turnover, chaperones Isoprenylcysteine carboxyl methyltransferase (ICMT) family;; Phospholipid methyltransferase Protein F21F3.3 {ECO:0000313|EMBL:CCD69818.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F21F3.3 [Caenorhabditis elegans] Y4C6B.4 gene15341 132 142 126 569 603 658 5.49521000048972 6.31650297209 4.7489212899 23.037095 26.02787 27.591205 4.13798429710149e-22 2.1801121111409 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein Y4C6B.4, isoform a {ECO:0000313|EMBL:CCD71125.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein Y4C6B.4, isoform a [Caenorhabditis elegans] ZK1225.4 gene3727 81 90 86 37 41 50 3.06635 3.45197 3.29884 1.47486 1.73611 2.14559 0.00819797862205267 -1.01918765778866 down -- -- -- -- -- [A] RNA processing and modification -- Protein ZK1225.4 {ECO:0000313|EMBL:CAA18371.1} OS=Caenorhabditis elegans PE=4 SV=1 A RNA processing and modification Protein ZK1225.4 [Caenorhabditis elegans] col-101 gene13287 6323 4451 5355 2586 1736 2017 339.8795 230.0567 278.5632 130.1196 88.4238 100.5555 3.61461003302717e-07 -1.36273559908954 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Nematode cuticle collagen N-terminal domain;; Collagen triple helix repeat (20 copies) Protein COL-101, isoform a {ECO:0000313|EMBL:CCD69690.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein COL-101 [Caenorhabditis elegans] cal-8 gene6109 49 48 31 93 67 113 12.4664 11.2194 7.74267 23.3508 19.489 31.6704 0.0078634778158735 1.07933989931427 up [TZDR] Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only Molecular Function: calcium ion binding (GO:0005509);; -- -- [T] Signal transduction mechanisms EF hand;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair;; EF hand;; Cytoskeletal-regulatory complex EF hand;; Secreted protein acidic and rich in cysteine Ca binding region;; Uncharacterised protein family (UPF0154) Protein CAL-8 {ECO:0000313|EMBL:CCD69292.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CAL-8 [Caenorhabditis elegans] gsto-2 gene11826 46 73 59 144 149 138 4.91347 7.68942 6.16644 15.328 16.0799 15.246 8.26598370363774e-05 1.26245324519156 up [O] Posttranslational modification, protein turnover, chaperones Molecular Function: protein binding (GO:0005515);; K00799|1.9647e-176|cel:CELE_C02D5.3|gsto-2; Protein GSTO-2; K00799 glutathione S-transferase [EC:2.5.1.18] (A) Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982) [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein C02D5.4 {ECO:0000313|EMBL:CCD62561.1} OS=Caenorhabditis elegans PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein GSTO-2 [Caenorhabditis elegans] nhr-11 gene18779 376 407 449 1385 1405 1488 15.556687556 17.222709 18.964508712 58.49286 59.47078418 63.2576 4.05247336408928e-20 1.78173578550099 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Nuclear receptor NHR-11 {ECO:0000313|EMBL:AAR11983.1} OS=Caenorhabditis elegans PE=2 SV=1 G Carbohydrate transport and metabolism Protein NHR-11, isoform a [Caenorhabditis elegans] dhs-20 gene37112 1941 2125 1512 3879 3581 4563 79.57526 81.875721 59.300872 141.5654 125.21834 165.1916 8.03942898950342e-09 1.09465270574459 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- -- -- [QR] Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain;; Fungal family of unknown function (DUF1776) Protein DHS-20 {ECO:0000313|EMBL:CAA98465.3} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein DHS-20 [Caenorhabditis elegans] cyp-13A5 gene7786 284 356 289 1277 1211 1109 10.948 13.8392 11.1874 50.9388 48.9633 46.7993 2.49838202385411e-22 1.93928024602541 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17861|0|cel:CELE_T10B9.2|cyp-13A5; Protein CYP-13A5; K17861 cytochrome P450, family 13 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Putative uncharacterized protein {ECO:0000313|EMBL:EGT38206.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-13A5 [Caenorhabditis elegans] lys-4 gene19808 80 81 107 322 230 264 12.5139 12.2967 16.245 50.2099 37.5138 43.48 1.92472928050471e-09 1.59110905815238 up -- -- Molecular Function: lysozyme activity (GO:0003796);; Biological Process: peptidoglycan catabolic process (GO:0009253);; Biological Process: cell wall macromolecule catabolic process (GO:0016998);; -- -- -- -- Glycosyl hydrolases family 25 Protein LYS-4 {ECO:0000313|EMBL:CAA97797.1} OS=Caenorhabditis elegans PE=4 SV=1 Z Cytoskeleton Protein LYS-4 [Caenorhabditis elegans] F25E5.8 gene35333 1296 1206 1641 3146 3098 3646 95.34659425 87.0979580000156 120.222862976133 227.328188014231 226.09693007827 267.403496062679 1.01034094352839e-11 1.24064355367297 up -- -- -- -- -- -- -- -- Protein F25E5.8, isoform a {ECO:0000313|EMBL:CCD65093.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F25E5.8, isoform a [Caenorhabditis elegans] sams-1 gene44869 5408 6199 4485 11126 11327 10570 130.2955 137.0081 104.9875 243.1462 233.16571 216.52624 4.66493558085639e-08 1.02365269292325 up [H] Coenzyme transport and metabolism Molecular Function: methionine adenosyltransferase activity (GO:0004478);; Biological Process: S-adenosylmethionine biosynthetic process (GO:0006556);; K00789|0|cel:CELE_C49F5.1|sams-1; Protein SAMS-1; K00789 S-adenosylmethionine synthetase [EC:2.5.1.6] (A) Cysteine and methionine metabolism (ko00270);; Biosynthesis of amino acids (ko01230) [H] Coenzyme transport and metabolism S-adenosylmethionine synthetase, C-terminal domain;; S-adenosylmethionine synthetase, central domain;; S-adenosylmethionine synthetase, N-terminal domain S-adenosylmethionine synthase {ECO:0000256|RuleBase:RU000541} OS=Caenorhabditis japonica PE=3 SV=1 BK Chromatin structure and dynamics;; Transcription Protein SAMS-1 [Caenorhabditis elegans] lipl-4 gene34978 87 66 36 128 121 165 5.2247550748 4.087452 2.1460005421 7.76184821375 7.7638007379 10.8657116253 0.00231254931720317 1.11797316706143 up [R] General function prediction only Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Partial alpha/beta-hydrolase lipase region;; alpha/beta hydrolase fold Lipase {ECO:0000256|PIRNR:PIRNR000862} OS=Caenorhabditis elegans PE=3 SV=1 I Lipid transport and metabolism Protein LIPL-4 [Caenorhabditis elegans] msd-4 gene10637 82 117 97 37 29 45 85.9181 110.914 98.157 38.9897 41.4603 54.9168 6.63383290761416e-05 -1.42846122950057 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Protein MSD-4 {ECO:0000313|EMBL:CCD66784.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein MSD-1 [Caenorhabditis elegans] ZC190.6 gene35803 7 12 19 53 51 71 0.596630842561 0.7545858301 1.4219307134 3.086481847 3.14617580489 5.519920322 5.00825006494415e-07 2.18871905373686 up -- -- -- -- -- -- -- -- Protein ZC190.6 {ECO:0000313|EMBL:CCD70124.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein ZC190.6 [Caenorhabditis elegans] K09C6.9 gene33147 240 173 233 122 74 75 38.9786 26.8177 36.6124 19.2513 12.5845 12.3181 2.71136049251764e-05 -1.26921767111416 down -- -- -- -- -- -- -- -- Protein K09C6.9 {ECO:0000313|EMBL:CCD71079.1} OS=Caenorhabditis elegans PE=4 SV=4 R General function prediction only Protein K09C6.9 [Caenorhabditis elegans] C12D5.9 gene35437 74 73 70 46 22 20 5.03315 5.11607 4.8498 3.2452 1.62397 1.5354 0.000998214520877758 -1.31790078974405 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein C12D5.9 {ECO:0000313|EMBL:CCD64277.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein C12D5.9 [Caenorhabditis elegans] acs-2 gene38765 1825 1306 2674 32200 32990 34427 170.7980559245 150.089222699582 251.9854605 743.72680314 761.8494 806.36508 1.80868069461288e-93 4.08540168846496 up [IQ] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; K01897|0|cel:CELE_F28F8.2|acs-2; Protein ACS-2; K01897 long-chain acyl-CoA synthetase [EC:6.2.1.3] (A) Fatty acid biosynthesis (ko00061);; Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; Peroxisome (ko04146) [I] Lipid transport and metabolism AMP-binding enzyme;; AMP-binding enzyme C-terminal domain Protein ACS-2 {ECO:0000313|EMBL:CAB03012.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein ACS-2 [Caenorhabditis elegans] fbxa-143 gene39035 44 72 66 156 164 155 2.944767 4.87477 4.409774 10.66293 11.395011 11.12516 9.54811626526227e-06 1.3704303981123 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-143 {ECO:0000313|EMBL:CAJ43453.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein FBXA-143 [Caenorhabditis elegans] C50B6.7 gene37864 331 318 288 98 94 85 9.40229 9.16581 8.26488 2.859 2.81302 2.64193 4.65217096879373e-12 -1.77236995536771 down [G] Carbohydrate transport and metabolism Molecular Function: catalytic activity (GO:0003824);; Biological Process: carbohydrate metabolic process (GO:0005975);; -- -- [G] Carbohydrate transport and metabolism Alpha amylase, catalytic domain;; Alpha amylase, C-terminal all-beta domain Alpha-amylase {ECO:0000256|RuleBase:RU361134} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein C50B6.7 [Caenorhabditis elegans] pfk-1.2 gene36133 106 122 138 51 50 45 2.71597 3.20453 3.65091 1.35455 1.38212 1.28068 6.36627804250023e-05 -1.34033213518557 down [G] Carbohydrate transport and metabolism Molecular Function: 6-phosphofructokinase activity (GO:0003872);; Biological Process: glycolytic process (GO:0006096);; K00850|0|cel:CELE_C50F4.2|pfk-2; Protein PFK-2; K00850 6-phosphofructokinase 1 [EC:2.7.1.11] (A) Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; RNA degradation (ko03018) [G] Carbohydrate transport and metabolism Phosphofructokinase Protein CBG19122 {ECO:0000313|EMBL:CAP36423.2} OS=Caenorhabditis briggsae PE=3 SV=2 R General function prediction only Protein PFK-2 [Caenorhabditis elegans] stdh-3 gene38072 5 16 3 33 44 30 0.407647 1.3226 0.29796 2.73551 3.74592 2.68389 3.8067309126192e-05 2.14672096939964 up [R] General function prediction only -- -- -- [I] Lipid transport and metabolism short chain dehydrogenase;; KR domain;; Fungal family of unknown function (DUF1776) Protein CBR-STDH-1 {ECO:0000313|EMBL:CAP30523.1} OS=Caenorhabditis briggsae PE=3 SV=1 R General function prediction only Protein STDH-3 [Caenorhabditis elegans] W03F9.4 gene32927 705 990 819 274 333 273 15.353055019099 21.7257750000038 17.6163200028398 5.7401500252903 6.88609 5.5163294 1.82576180537788e-10 -1.52773789730129 down -- -- Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; -- -- [I] Lipid transport and metabolism Choline/Carnitine o-acyltransferase Protein W03F9.4 {ECO:0000313|EMBL:CCD74278.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein W03F9.4 [Caenorhabditis elegans] gst-30 gene5890 126 132 129 474 338 389 16.0898 16.35077 16.74189 61.04942 44.47077 51.3322 2.32087351966814e-11 1.61922761521313 up -- -- Molecular Function: protein binding (GO:0005515);; K00799|3.64552e-157|cel:CELE_ZK546.11|gst-30; Protein GST-30; K00799 glutathione S-transferase [EC:2.5.1.18] (A) Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982) [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein GST-30 {ECO:0000313|EMBL:CCD73222.1} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein GST-30 [Caenorhabditis elegans] sri-36 gene5071 572 579 546 346 241 232 68.8106000388105 63.163200018989 60.1041000420165 36.013600205687 29.863740112084 27.204550290824 3.49249362115964e-06 -1.06588487193743 down -- -- -- -- -- -- -- Serpentine type 7TM GPCR chemoreceptor Sri;; Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Srd Protein SRI-36 {ECO:0000313|EMBL:CCD68471.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein SRI-36 [Caenorhabditis elegans] clec-166 gene13518 245 237 176 1130 1138 1358 12.091786 11.14712 8.411472 53.90481 55.17814 64.5779 1.77364387541261e-33 2.44877480175122 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-166 {ECO:0000313|EMBL:CCD63950.2} OS=Caenorhabditis elegans PE=4 SV=2 W Extracellular structures CLEC-166 [Caenorhabditis elegans] nspe-3 gene8735 0 3 1 47 25 48 0 62.2825 32.7816 923.569 859.993 1380.13 2.69026733301722e-09 4.89698775944121 up -- -- -- -- -- -- -- Protein of unknown function (DUF1412) Protein NSPE-3 {ECO:0000313|EMBL:CAB54403.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein NSPE-3 [Caenorhabditis elegans] ttr-42 gene41447 131 161 203 105 68 69 54.6849 59.6854 78.6455 42.9462 34.8039 32.1642 0.00376017017240986 -1.0478038422011 down -- -- -- -- -- -- -- Transthyretin-like family Protein TTR-42 {ECO:0000313|EMBL:CCD71666.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein TTR-42 [Caenorhabditis elegans] C45B2.1 gene42729 374 586 641 136 97 125 689.329 977.364 1127.47 256.201 282.235 301.151 5.25029592041405e-07 -2.17535065264838 down -- -- -- -- -- -- -- -- Protein C45B2.1 {ECO:0000313|EMBL:CCD63809.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C45B2.1 [Caenorhabditis elegans] EGAP4.1 gene43796 262 352 83 482 481 564 29.641027095448 37.66019547 12.183621052 53.364424973447 54.16418264 63.413609301 0.00749882167251827 1.1200024644009 up -- -- -- -- -- -- -- -- Protein M02D8.6 {ECO:0000313|EMBL:CCD68797.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein EGAP4.1 [Caenorhabditis elegans] F41C3.4 gene5813 1733 1890 2285 5997 5324 5941 173.814173826 153.9588385295 207.702019213 326.2807981213 287.45953601 332.151424674 4.86306406228319e-18 1.53227401860062 up -- -- -- -- -- [P] Inorganic ion transport and metabolism Got1/Sft2-like family Putative uncharacterized protein {ECO:0000313|EMBL:EFO91377.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein F41C3.4 [Caenorhabditis elegans] gcy-13 gene37478 13 21 6 28 56 52 0.253806410267902 0.416512510000024 0.13195523161 0.57204328219 1.22119820316599 1.13582679004402 0.00656167873063754 1.75511650854464 up [T] Signal transduction mechanisms Molecular Function: guanylate cyclase activity (GO:0004383);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: cGMP biosynthetic process (GO:0006182);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; -- -- [T] Signal transduction mechanisms Adenylate and Guanylate cyclase catalytic domain;; Receptor family ligand binding region;; Protein tyrosine kinase;; Protein kinase domain;; Heme NO binding associated Guanylate cyclase {ECO:0000256|RuleBase:RU003431} OS=Caenorhabditis elegans PE=3 SV=3 S Function unknown Protein GCY-13 [Caenorhabditis elegans] F28A12.3 gene35789 826 829 731 2705 2559 2757 32.6964740242199 31.9363400068369 29.61230649023 105.044800001167 97.857 102.6206 2.20545463784554e-21 1.73524079077697 up -- -- -- -- -- -- -- Activin types I and II receptor domain Protein F28A12.3 {ECO:0000313|EMBL:CCD70114.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F28A12.3 [Caenorhabditis elegans] F23B12.1 gene38287 81 90 84 20 46 30 5.73619 6.16219 5.77498 1.40305 3.27737 2.19231 0.00016150269842171 -1.42229375811564 down [T] Signal transduction mechanisms Molecular Function: hydrolase activity (GO:0016787);; -- -- [TR] Signal transduction mechanisms;; General function prediction only Calcineurin-like phosphoesterase Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein F23B12.1 [Caenorhabditis elegans] clec-143 gene7999 85 109 79 48 25 28 5.01951 6.4152 4.6748 2.84145 1.56425 1.79909 8.27352270357113e-05 -1.44910985424224 down -- -- -- -- -- -- -- von Willebrand factor type A domain;; von Willebrand factor type A domain Protein CLEC-143 {ECO:0000313|EMBL:CAA88487.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein CLEC-143 [Caenorhabditis elegans] C23F12.3 gene44020 15 17 11 28 41 41 0.576855 0.643302 0.403925 1.030580134214 1.44818 1.4388 0.00869171819573113 1.34254079245095 up -- -- -- -- -- -- -- -- Protein C23F12.3 {ECO:0000313|EMBL:CCD65282.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C23F12.3 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_531 50 43 45 105 107 107 1.12493134 1.044341 1.046925 2.619942 2.713044 2.586697 0.000755872325929623 1.19455849593464 up -- -- -- -- -- -- -- Protein of unknown function (DUF684);; Protein of unknown function (DUF684) Protein Y102A5C.4 {ECO:0000313|EMBL:CAA20945.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown -- Y39H10A.1 gene34034 157 144 50 290 287 413 65.8773 54.12 20.6182 115.056 150.126 180.537 0.000569953940082758 1.48364150252758 up -- -- -- -- -- -- -- -- Protein Y39H10A.1 {ECO:0000313|EMBL:CCD73282.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein Y39H10A.1 [Caenorhabditis elegans] aqp-1 gene6863 263 225 274 4350 3699 3938 25.042148362 21.3615585233 26.203071684 416.5920739493 381.6490878035 399.4010876603 1.3277231374688e-93 3.96063474883067 up [G] Carbohydrate transport and metabolism Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; K09886|0|cel:CELE_F32A5.5|aqp-1; Protein AQP-1, isoform B; K09886 aquaglyceroporin related protein, invertebrate (A) -- [G] Carbohydrate transport and metabolism Major intrinsic protein Protein AQP-1, isoform a {ECO:0000313|EMBL:CCD66276.1} OS=Caenorhabditis elegans PE=3 SV=2 O Posttranslational modification, protein turnover, chaperones Protein AQP-1, isoform a [Caenorhabditis elegans] T05E12.3 gene39444 186 209 104 460 365 351 17.309816 18.93835 9.62708 42.74855 36.20318 34.82873 1.32705003597427e-05 1.22340891581785 up -- -- Biological Process: protein homooligomerization (GO:0051260);; -- -- [P] Inorganic ion transport and metabolism BTB/POZ domain Protein T05E12.3 {ECO:0000313|EMBL:CAB04686.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein T05E12.3 [Caenorhabditis elegans] H12D21.5 gene38461 1714 1830 1609 11290 11735 13389 94.6637113241 96.82238882992 84.4468583323 611.93393637479 623.012271404676 707.515560163868 6.37118743305007e-54 2.80737374477892 up -- -- -- -- -- [V] Defense mechanisms -- Protein H12D21.5 {ECO:0000313|EMBL:CAB07431.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein H12D21.5 [Caenorhabditis elegans] msp-50 gene5999 71 92 122 37 22 27 32.5274 37.7011 53.0167 16.5567 12.1625 13.5167 0.000112050109674102 -1.74396425543423 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein MSP-31 [Caenorhabditis elegans] cpr-5 gene33206 1470 1019 1375 2806 3084 2914 74.1298 48.4355 67.3356 130.79594 142.6222488 131.861545222 1.98903047012766e-10 1.17321542703306 up -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; K01363|0|cel:CELE_W07B8.5|cpr-5; Protein CPR-5; K01363 cathepsin B [EC:3.4.22.1] (A) Lysosome (ko04142) [O] Posttranslational modification, protein turnover, chaperones Papain family cysteine protease Protein CBR-CPR-5 {ECO:0000313|EMBL:CAP22409.1} OS=Caenorhabditis briggsae PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein CPR-5 [Caenorhabditis elegans] T16H12.9 gene12363 254 257 189 452 421 548 15.707816 15.7852500000003 11.838476166272 27.74667 26.8605580128664 34.95096 2.74364441504808e-05 1.00805581421261 up -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EGT33751.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein T16H12.9 [Caenorhabditis elegans] aat-7 gene4633 11 13 6 57 51 39 0.532223368 0.632492932 0.313191795824 2.652453 2.55224320251 1.82455480422 9.68920271015587e-07 2.27959580584262 up [E] Amino acid transport and metabolism Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; -- -- [E] Amino acid transport and metabolism Amino acid permease;; Amino acid permease Protein AAT-7 {ECO:0000313|EMBL:CCD71779.2} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein AAT-7 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_52 58 33 51 23 9 8 1.356716 0.65059 0.97992 0.449851000055407 0.197522 0.16554183971 0.00083201696732994 -1.84528479639505 down -- -- -- -- -- -- -- -- -- K Transcription -- C09D4.3 gene1219 119 174 160 76 67 69 5.82719 8.33376 7.67254 4.272949 2.6203136 3.37004 0.000488377131404931 -1.10935129571552 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein kinase domain;; Protein tyrosine kinase Protein C09D4.3 {ECO:0000313|EMBL:CCD63888.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C09D4.3 [Caenorhabditis elegans] F46F2.5 gene46041 52 67 22 104 88 100 2.249516 2.83954 0.949972 4.39944 3.56853 4.0791 0.00512631282268377 1.03800540946635 up -- -- -- -- -- -- -- -- Protein F46F2.5 {ECO:0000313|EMBL:CAE17836.3} OS=Caenorhabditis elegans PE=4 SV=3 T Signal transduction mechanisms Protein F46F2.5 [Caenorhabditis elegans] fbxa-44 gene39360 58 99 78 181 129 219 4.09606 6.71043 5.43886 12.575 9.65606 16.13206 0.00515275687081728 1.15737829029061 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain;; F-box-like domain Protein FBXA-44 {ECO:0000313|EMBL:CAB04070.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein FBXA-44 [Caenorhabditis elegans] F55G11.2 gene20331 16048 18341 8629 4181 3034 3163 1130.84766 1269.9264 594.68772 299.78496 229.08803 241.10884 0.000543600624034467 -2.06476790502481 down -- -- -- -- -- -- -- CUB-like domain Protein F55G11.2 {ECO:0000313|EMBL:CAB05218.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F55G11.2 [Caenorhabditis elegans] clec-190 gene25715 266 195 149 102 55 56 29.4412 19.9028 15.6313 11.0844 6.36705 6.27185 0.00215293882523635 -1.53326106733595 down -- -- -- -- -- -- -- -- Protein CLEC-190 {ECO:0000313|EMBL:CAB70254.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CLEC-190 [Caenorhabditis elegans] ugt-18 gene37679 753 780 601 1739 1588 1779 29.55207 31.08794 23.72013 70.4415 65.336 76.4944 8.12437299443483e-11 1.24493324936933 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-18 {ECO:0000313|EMBL:CAA99950.2} OS=Caenorhabditis elegans PE=3 SV=2 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein UGT-18 [Caenorhabditis elegans] nhr-57 gene34170 488 368 341 3140 3214 3731 17.3173800339133 13.3799700255095 13.0975700340938 108.952700000009 116.761900000879 135.145400000594 2.9107439646879e-60 3.06065467736144 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) Nuclear receptor NHR-57 {ECO:0000313|EMBL:AAK17978.1} (Fragment) OS=Caenorhabditis elegans PE=2 SV=1 K Transcription nuclear receptor NHR-57 [Caenorhabditis elegans] C32H11.4 gene20310 10284 11174 7337 2314 1892 1936 666.043 705.842 464.019 145.804 120.21 121.278 4.596797086343e-12 -2.24274578244887 down -- -- -- -- -- -- -- CUB-like domain Protein C32H11.4 {ECO:0000313|EMBL:CAB05131.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C32H11.4 [Caenorhabditis elegans] T24E12.5 gene5563 348 314 228 699 792 792 7.40766254214 6.8371677515 5.0247429284514 15.776278 15.9119131068 17.45025669068 3.52852959288149e-10 1.34558989436369 up -- -- -- -- -- -- -- NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Protein T24E12.5 {ECO:0000313|EMBL:CCD69332.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein T24E12.5 [Caenorhabditis elegans] W09C2.8 gene19007 92 78 51 34 17 31 665.596 532.602 373.458 280.117 241.779 363.323 0.00265675334968792 -1.44461947428786 down -- -- -- -- -- -- -- -- Protein W09C2.8 {ECO:0000313|EMBL:CAX65078.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein W09C2.8 [Caenorhabditis elegans] Y69E1A.8 gene19550 44 48 65 13 20 24 3.0107851326 3.31245853101 4.4157611882 0.92539222084 1.4215517796 1.85223 0.000918631363164522 -1.47548094387827 down -- -- -- -- -- -- -- -- Protein Y69E1A.8 {ECO:0000313|EMBL:CAA22260.2} OS=Caenorhabditis elegans PE=4 SV=2 G Carbohydrate transport and metabolism Protein Y69E1A.8 [Caenorhabditis elegans] F14D2.19 gene5383 421 464 198 773 714 997 10.69922 12.81605 4.359339 18.21752 18.49847 26.19801 0.000943274049614278 1.1852110288281 up -- -- -- -- -- -- -- -- Protein F14D2.19 {ECO:0000313|EMBL:CCD69495.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F14D2.19 [Caenorhabditis elegans] nhr-221 gene33964 30 39 31 11 10 7 1.670303 2.1099286347 1.7048735827 0.6149854 0.6180077075 0.4006852064 0.000437721448450493 -1.85055797856169 down -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- -- -- Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Protein NHR-221 {ECO:0000313|EMBL:CCD63572.1} OS=Caenorhabditis elegans PE=3 SV=2 K Transcription Protein NHR-221 [Caenorhabditis elegans] F26A1.19 gene10621 192 213 98 348 331 456 47.33119 72.76871 39.58076 85.22704 36.25047 61.15563 0.000746241195654008 1.16158848254909 up -- -- -- -- -- -- -- -- Protein ACBP-7 {ECO:0000313|EMBL:CCD66806.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ACBP-7 [Caenorhabditis elegans] E01G6.3 gene44974 118 98 74 219 232 226 4.28854 3.575069 2.715638 8.00075 8.54811 8.924538 1.74564212332576e-05 1.2093276207785 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein E01G6.3 {ECO:0000313|EMBL:CAA93533.2} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein E01G6.3 [Caenorhabditis elegans] irld-14 gene38494 35 32 30 8 16 12 2.6496421385 2.455444241 2.4100969734 0.62151992072 1.3046720697097 1.1634598297 0.00659589126184467 -1.44316936024665 down -- -- -- -- -- -- -- Receptor L domain Protein IRLD-14 {ECO:0000313|EMBL:CAB01661.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein IRLD-14 [Caenorhabditis elegans] spch-2 gene1485 100 131 126 39 63 65 16.8425 21.1275 20.9125 6.51127 10.4492 10.8061 0.00120392641567711 -1.10905355950178 down -- -- -- -- -- -- -- -- Protein T27A3.4 {ECO:0000313|EMBL:CCD72004.1} OS=Caenorhabditis elegans PE=4 SV=1 H Coenzyme transport and metabolism Protein T27A3.4 [Caenorhabditis elegans] pals-15 gene3705 20 9 13 50 69 83 0.952323 0.489866 0.586791 2.46342 3.616554 4.777967 5.28113632462407e-07 2.25133947840147 up -- -- -- -- -- -- -- -- Protein F22G12.7 {ECO:0000313|EMBL:CAJ58497.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F22G12.7 [Caenorhabditis elegans] Y42H9AR.5 gene18445 119 141 108 53 39 73 61.44383 70.24237 52.95695 24.08926 25.32805 39.94314 0.000531649383325552 -1.1705478286113 down -- -- -- -- -- -- -- -- Protein Y42H9AR.5 {ECO:0000313|EMBL:CCD71170.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y42H9AR.5 [Caenorhabditis elegans] ZK512.7 gene12019 180 235 204 73 60 61 71.307 83.184 74.9769 28.5912 28.3663 27.0711 3.07892813556556e-09 -1.68791783930336 down -- -- -- -- -- -- -- -- Protein DECR-1.1 {ECO:0000313|EMBL:CCD69617.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK512.7 [Caenorhabditis elegans] acs-19 gene10303 5198 5028 7716 19194 18728 16926 133.172342 129.639969995 198.43716269 496.0409961 492.76024 459.7304715 1.71995062820078e-18 1.59690296155509 up [I] Lipid transport and metabolism Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; K01895|0|cel:CELE_C36A4.9|acs-19; Protein ACS-19, isoform B; K01895 acetyl-CoA synthetase [EC:6.2.1.1] (A) Glycolysis / Gluconeogenesis (ko00010);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200) [I] Lipid transport and metabolism AMP-binding enzyme;; AMP-binding enzyme C-terminal domain Acetyl-coenzyme A synthetase {ECO:0000256|RuleBase:RU361147} OS=Caenorhabditis elegans PE=3 SV=1 G Carbohydrate transport and metabolism Protein ACS-19, isoform a [Caenorhabditis elegans] far-3 gene37755 2586 2069 2722 12188 9484 10099 497.891 374.43 496.751 2335.18 1933.67 2078.54 5.84783406147691e-26 2.09133212222078 up -- -- Molecular Function: lipid binding (GO:0008289);; -- -- -- -- Nematode fatty acid retinoid binding protein (Gp-FAR-1) Protein FAR-3 {ECO:0000313|EMBL:CAB01422.1} OS=Caenorhabditis elegans PE=4 SV=1 TZ Signal transduction mechanisms;; Cytoskeleton Protein FAR-3 [Caenorhabditis elegans] odc-1 gene35117 1117 1003 881 2519 2339 2521 40.3716370796 36.601649719 33.418347 88.0152470986 81.90178 89.22907 4.76580212685095e-12 1.28389923415964 up [E] Amino acid transport and metabolism Molecular Function: catalytic activity (GO:0003824);; K01581|0|cel:CELE_K11C4.4|odc-1; Protein ODC-1; K01581 ornithine decarboxylase [EC:4.1.1.17] (A) Arginine and proline metabolism (ko00330);; Glutathione metabolism (ko00480) [E] Amino acid transport and metabolism Pyridoxal-dependent decarboxylase, pyridoxal binding domain;; Pyridoxal-dependent decarboxylase, C-terminal sheet domain CRE-ODC-1 protein {ECO:0000313|EMBL:EFP05480.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 T Signal transduction mechanisms Protein ODC-1 [Caenorhabditis elegans] col-122 gene18986 12466 13330 22028 5378 5180 5747 658.106 637.01 1060.83 248.098 231.925 235.719 0.00324234216900475 -1.56752321859535 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-122 {ECO:0000313|EMBL:CAA92476.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein COL-122 [Caenorhabditis elegans] C29F3.7 gene38670 4299 5215 3093 1374 1155 1231 182.940926 210.64534 125.03129 56.798929 49.710344 53.99511 3.59131525034919e-06 -1.75872031195105 down -- -- -- -- -- -- -- CUB-like domain Protein C29F3.7, isoform a {ECO:0000313|EMBL:CAB02803.3} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein C29F3.7, isoform a [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_744 154 177 125 46 87 53 1.86638 2.09478 1.48392 0.538124 0.983528 0.603773 3.05595466310628e-05 -1.30643425139143 down -- -- -- -- -- [R] General function prediction only Reverse transcriptase (RNA-dependent DNA polymerase);; Endonuclease-reverse transcriptase;; Endonuclease/Exonuclease/phosphatase family Reverse transcriptase {ECO:0000313|EMBL:AAC72298.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown PREDICTED: craniofacial development protein 2-like [Camponotus floridanus] icl-1 gene33104 20137 13457 22406 46405 60615 62696 318.113061893 207.94482 346.7200867383 704.343446 867.9810846682 912.011080687 4.94398775886664e-10 1.58479920542874 up [C] Energy production and conversion Molecular Function: isocitrate lyase activity (GO:0004451);; Molecular Function: malate synthase activity (GO:0004474);; Biological Process: glyoxylate cycle (GO:0006097);; Biological Process: carboxylic acid metabolic process (GO:0019752);; -- -- [C] Energy production and conversion Malate synthase;; Isocitrate lyase family;; Phosphoenolpyruvate phosphomutase Malate synthase {ECO:0000256|RuleBase:RU000555} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 R General function prediction only Protein ICL-1, isoform a [Caenorhabditis elegans] col-38 gene7335 2601 2992 3170 845 1040 785 186.491 207.368 223.202 59.7337 73.4991 55.5126 1.51930355929207e-21 -1.72864182827537 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-38 {ECO:0000313|EMBL:CAA90250.1} OS=Caenorhabditis elegans PE=4 SV=2 J Translation, ribosomal structure and biogenesis Protein COL-38 [Caenorhabditis elegans] lipl-5 gene32971 4618 4276 4638 17991 16043 18412 251.3511658424 228.38408715337 253.346283300668 955.567165801935 891.358380805342 993.409463460004 6.86142113961985e-27 1.94001703494958 up [R] General function prediction only Biological Process: lipid metabolic process (GO:0006629);; K01052|0|cbr:CBG01370|Hypothetical protein CBG01370; K01052 lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] (A) Steroid biosynthesis (ko00100);; Lysosome (ko04142) [I] Lipid transport and metabolism Partial alpha/beta-hydrolase lipase region;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family Lipase {ECO:0000256|PIRNR:PIRNR000862} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein LIPL-5, isoform a [Caenorhabditis elegans] lipl-1 gene37716 735 772 672 2322 2480 2419 43.9223 45.7305 39.7997 139.4527 155.9438 153.0293 1.43349372052801e-20 1.71477604506514 up [R] General function prediction only Biological Process: lipid metabolic process (GO:0006629);; K01052|0|cel:CELE_F54F3.3|lipl-1; Protein LIPL-1; K01052 lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] (A) Steroid biosynthesis (ko00100);; Lysosome (ko04142) [I] Lipid transport and metabolism Partial alpha/beta-hydrolase lipase region;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family Lipase {ECO:0000256|PIRNR:PIRNR000862} OS=Caenorhabditis elegans PE=3 SV=2 I Lipid transport and metabolism Protein LIPL-1 [Caenorhabditis elegans] C05C12.5 gene19667 64 81 94 28 45 46 10.067814461 11.5678653285 13.9706154551 4.720723 7.499436784 7.6617168689 0.00989568003518049 -1.01947109262613 down -- -- -- -- -- -- -- -- Protein C05C12.5 {ECO:0000313|EMBL:CAA92722.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C05C12.5 [Caenorhabditis elegans] pqn-60 gene33013 201 257 223 572 509 647 59.2508 69.4508 61.4307 165.334 168.981 206.491 3.84437448978458e-09 1.32975716286944 up -- -- -- -- -- -- -- Domain of unknown function DUF148 Protein PQN-60 {ECO:0000313|EMBL:CCD64483.1} OS=Caenorhabditis elegans PE=1 SV=1 K Transcription Protein PQN-60 [Caenorhabditis elegans] col-166 gene42822 0 0 0 24 1291 2850 0.021809 0.0266598 0.0186159 1.1368 60.6554 130.361 0.000432128345592913 Inf up -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-166, isoform b {ECO:0000313|EMBL:CCD74395.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein COL-166, isoform b [Caenorhabditis elegans] C34D4.2 gene18053 78 80 92 19 32 46 5.79845 5.78812 6.83194 1.42744 2.56866 3.58577 0.000286177207599295 -1.37900560170449 down [T] Signal transduction mechanisms Molecular Function: hydrolase activity (GO:0016787);; K01090|0|cel:CELE_C34D4.2|C34D4.2; Protein C34D4.2; K01090 protein phosphatase [EC:3.1.3.16] (A) -- [TR] Signal transduction mechanisms;; General function prediction only Calcineurin-like phosphoesterase Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273} OS=Caenorhabditis elegans PE=3 SV=2 O Posttranslational modification, protein turnover, chaperones Protein C34D4.2 [Caenorhabditis elegans] clec-9 gene39300 29 25 6 165 201 219 1.50312 1.19117 0.310932 7.73667 9.42226 9.58503 1.25973770375931e-24 3.27334670059235 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain Protein CLEC-9 {ECO:0000313|EMBL:CAB16536.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein CLEC-9 [Caenorhabditis elegans] oac-23 gene14138 139 139 87 50 55 51 4.26789 4.18286 2.536456 1.588886717 1.827849365 1.7138396307 0.000467709014207483 -1.23959752155874 down [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- -- -- Acyltransferase family Protein OAC-23 {ECO:0000313|EMBL:CCD70193.1} OS=Caenorhabditis elegans PE=4 SV=1 H Coenzyme transport and metabolism Protein OAC-23 [Caenorhabditis elegans] F21G4.3 gene44164 41 41 46 16 22 14 2.7598 2.78451039 3.09624 1.119411 1.581352 1.03403851 0.00636914270124873 -1.31378011244468 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein F21G4.3 {ECO:0000313|EMBL:CAB02666.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F21G4.3 [Caenorhabditis elegans] F10F2.2 gene10531 711 626 610 1411 1555 1451 9.90096 8.80682 8.53562 19.8259 22.59683 20.94959 2.36853270322593e-09 1.16770670817517 up [F] Nucleotide transport and metabolism -- K01952|0|cel:CELE_F10F2.2|F10F2.2; Protein F10F2.2; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] (A) Purine metabolism (ko00230) [F] Nucleotide transport and metabolism CobB/CobQ-like glutamine amidotransferase domain;; AIR synthase related protein, C-terminal domain;; AIR synthase related protein, N-terminal domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT52023.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein F10F2.2 [Caenorhabditis elegans] best-10 gene3992 25 23 26 7 5 9 1.4731756205 1.3312756272 1.491630534065 0.416779 0.3531113 1.035978 0.00197325383209462 -1.83151153251328 down -- -- -- -- -- [R] General function prediction only Bestrophin, RFP-TM, chloride channel Protein BEST-10 {ECO:0000313|EMBL:CAB05710.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein BEST-10 [Caenorhabditis elegans] col-135 gene25735 277 293 278 73 55 63 5.590735 6.215837 6.00505 1.54775444 1.19171169074 1.36566358332 4.00002734523678e-16 -2.16491964804925 down -- -- -- -- -- -- -- Collagen triple helix repeat (20 copies);; Protein of unknown function (DUF3113) Protein COL-135, isoform a {ECO:0000313|EMBL:CAD89749.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein COL-135, isoform a [Caenorhabditis elegans] col-19 gene40827 6581 8830 13213 3210 3054 3354 407.2149 518.466 791.272 185.9412 179.5728 192.3313 0.00562475641219402 -1.58824358596323 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Collagen {ECO:0000313|EMBL:AAA62505.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only collagen [Caenorhabditis elegans] cts-1 gene12399 13970 14339 15894 28554 32031 32402 473.826319 468.11234 545.07531 946.87366 983.915233 1001.9604310147 1.32654602317453e-07 1.05877998779788 up [C] Energy production and conversion Molecular Function: transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer (GO:0046912);; K01647|0|cel:CELE_T20G5.2|cts-1; Protein CTS-1; K01647 citrate synthase [EC:2.3.3.1] (A) Citrate cycle (TCA cycle) (ko00020);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230) [C] Energy production and conversion Citrate synthase Citrate synthase {ECO:0000256|RuleBase:RU000441} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 C Energy production and conversion Protein CTS-1 [Caenorhabditis elegans] msra-1 gene6892 865 823 609 2085 1665 2105 77.1882677 72.8918071047928 53.66881090087 203.7325069 151.0046338 197.066012 2.45911588335629e-12 1.33607338775237 up [O] Posttranslational modification, protein turnover, chaperones Molecular Function: peptide-methionine (S)-S-oxide reductase activity (GO:0008113);; Biological Process: oxidation-reduction process (GO:0055114);; K07304|3.7835e-153|cel:CELE_F43E2.5|msra-1; Protein MSRA-1; K07304 peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] (A) -- [O] Posttranslational modification, protein turnover, chaperones Peptide methionine sulfoxide reductase Protein MSRA-1 {ECO:0000313|EMBL:CCD63544.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein MSRA-1 [Caenorhabditis elegans] oac-9 gene1482 48 77 86 38 27 29 1.5914 2.55556 2.81178 1.31898 1.00614 1.12052 0.00758581781344346 -1.1811941691625 down -- -- Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [R] General function prediction only Acyltransferase family Protein OAC-9 {ECO:0000313|EMBL:CCD64209.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein OAC-9 [Caenorhabditis elegans] C36E6.8 gene46668 44 56 45 9 24 11 26.71611 29.03387 23.05613 4.589893 13.15942 9.250190863852 0.000149923492446196 -1.73298722329445 down -- -- -- -- -- -- -- -- Protein C36E6.8 {ECO:0000313|EMBL:CCD66903.1} OS=Caenorhabditis elegans PE=4 SV=1 A RNA processing and modification Protein C36E6.8 [Caenorhabditis elegans] T23F11.2 gene10545 94 98 103 29 32 50 7.683338 7.766969996 8.1409313435 2.507513 2.6552118281 4.28650556286 7.15536519665579e-05 -1.42367069227942 down -- -- -- -- -- -- -- -- Protein T23F11.2 {ECO:0000313|EMBL:CAA86457.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T23F11.2 [Caenorhabditis elegans] msp-40 gene5850 260 398 386 161 130 200 120.573 164.561 168.036 71.3707 69.7099 98.461 0.00107261120719262 -1.10198759052273 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein MSP-31 [Caenorhabditis elegans] ttr-14 gene44453 1070 1453 1545 610 714 612 40.69338 56.78758 60.36243 25.4306464 29.48553 27.30652 1.93763913099283e-05 -1.08515824505443 down -- -- Cellular Component: extracellular space (GO:0005615);; -- -- -- -- Transthyretin-like family Protein TTR-14 {ECO:0000313|EMBL:CAA92135.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein TTR-14 [Caenorhabditis elegans] F32H2.7 gene2309 246 322 345 144 170 145 13.2275 17.0075 18.3377 7.6163 8.98118 7.90175 0.000143575258802667 -1.00606840538226 down -- -- -- -- -- -- -- -- Protein F32H2.7 {ECO:0000313|EMBL:CAB04247.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F32H2.7 [Caenorhabditis elegans] lipl-3 gene33021 72 77 50 438 431 404 3.99887 4.22244 2.81218 24.0031 24.902 23.1214 1.33275176981445e-26 2.66396134595481 up [R] General function prediction only Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Partial alpha/beta-hydrolase lipase region;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family Lipase {ECO:0000256|PIRNR:PIRNR000862} OS=Caenorhabditis elegans PE=3 SV=2 K Transcription Protein LIPL-3 [Caenorhabditis elegans] aqp-7 gene41580 2068 2361 2009 5682 5562 5432 137.9974 146.0703 128.39924 361.669 365.9849 355.7029 2.53157758163109e-14 1.35928290494601 up [G] Carbohydrate transport and metabolism Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; K09886|0|cel:CELE_M02F4.8|aqp-7; Protein AQP-7; K09886 aquaglyceroporin related protein, invertebrate (A) -- [G] Carbohydrate transport and metabolism Major intrinsic protein Protein AQP-7 {ECO:0000313|EMBL:CCD66489.1} OS=Caenorhabditis elegans PE=3 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein AQP-7 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_606 712 837 839 1522 2110 2278 32.388244 36.420134 35.28682 65.36089 87.84772 101.28465 7.21306161040528e-06 1.29400304546326 up -- -- -- -- -- [R] General function prediction only -- Protein T09F5.12, isoform b {ECO:0000313|EMBL:CCF23443.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism -- F16B12.1 gene45607 20 13 23 63 41 43 0.6070007 0.3765131587 0.675497 1.872471 1.26498 1.3384505 0.00269081504418046 1.37599797559951 up -- -- -- -- -- -- -- CUB domain Protein F16B12.1 {ECO:0000313|EMBL:CAB02962.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein F16B12.1 [Caenorhabditis elegans] gst-19 gene8953 2618 2899 1777 9440 7843 9585 431.87 461.384 289.262 1531.68 1412.05 1618.25 7.62152993635793e-26 1.8677842899299 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein GST-19 {ECO:0000313|EMBL:CAB02294.1} OS=Caenorhabditis elegans PE=1 SV=1 O Posttranslational modification, protein turnover, chaperones Protein GST-19 [Caenorhabditis elegans] gcy-18 gene20285 188 181 130 333 452 434 2.8256427461 2.840642 1.930070985 5.227972382 7.31347834 7.225855 1.52863604221902e-07 1.27549986223165 up [T] Signal transduction mechanisms Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; K01769|0|cel:CELE_ZK896.8|gcy-18; Protein GCY-18; K01769 guanylate cyclase, other [EC:4.6.1.2] (A) Purine metabolism (ko00230) [T] Signal transduction mechanisms Adenylate and Guanylate cyclase catalytic domain;; Receptor family ligand binding region;; Protein kinase domain;; Protein tyrosine kinase Guanylate cyclase {ECO:0000256|RuleBase:RU003431} OS=Caenorhabditis elegans PE=2 SV=1 G Carbohydrate transport and metabolism Protein GCY-18 [Caenorhabditis elegans] gst-20 gene8946 2438 2104 2013 449 318 380 322.9716 267.9433 260.9545 58.57453 44.93261 49.7771 4.20918168294273e-41 -2.52942850997387 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain Protein GST-20 {ECO:0000313|EMBL:CAB07700.3} OS=Caenorhabditis elegans PE=1 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein GST-20 [Caenorhabditis elegans] srh-207 gene39953 238 270 210 534 504 557 13.224281 13.749868 11.225036 27.159185 24.2884600000001 23.59363 8.85665664008096e-07 1.13792670661739 up -- -- -- -- -- -- -- Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Sri;; Serpentine type 7TM GPCR chemoreceptor Str Protein SRH-207 {ECO:0000313|EMBL:CAB16545.2} OS=Caenorhabditis elegans PE=4 SV=2 I Lipid transport and metabolism Protein SRH-207 [Caenorhabditis elegans] bli-1 gene8087 1435 1431 1623 486 541 549 17.26184 16.66832 18.98304 5.54021 5.51072 5.70482 2.4375814113545e-15 -1.52430822702282 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Small acid-soluble spore protein O family;; Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain CRE-BLI-1 protein {ECO:0000313|EMBL:EFO86161.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein BLI-1 [Caenorhabditis elegans] lgc-54 gene35093 70 83 42 148 127 160 2.49412400000141 1.9699123 1.218681 4.54611331 4.999137 5.4082048 0.000391528580404732 1.14471211862639 up -- -- Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [T] Signal transduction mechanisms Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region Protein LGC-54 {ECO:0000313|EMBL:CCD68170.1} OS=Caenorhabditis elegans PE=3 SV=3 S Function unknown Protein LGC-54 [Caenorhabditis elegans] wrt-8 gene38664 106 123 71 34 54 44 3.67077 4.23041 2.44276 1.19298 1.83889 1.519 0.00383417565802946 -1.19682053774783 down -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; -- -- [T] Signal transduction mechanisms Hint module Protein CBR-WRT-4 {ECO:0000313|EMBL:CAP27407.1} OS=Caenorhabditis briggsae PE=4 SV=1 R General function prediction only Protein WRT-8 [Caenorhabditis elegans] ZK1251.3 gene19031 24 31 24 6 8 11 3.14788 4.00367 3.05076 0.793861 1.13935 1.49648 0.00361858805679287 -1.67248507247635 down -- -- Cellular Component: cytoplasm (GO:0005737);; Biological Process: lipid metabolic process (GO:0006629);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; -- -- [I] Lipid transport and metabolism 3-oxo-5-alpha-steroid 4-dehydrogenase;; Protein of unknown function (DUF1295) Protein ZK1251.3 {ECO:0000313|EMBL:CAA92499.1} OS=Caenorhabditis elegans PE=4 SV=1 B Chromatin structure and dynamics Protein ZK1251.3 [Caenorhabditis elegans] col-129 gene20019 6327 9302 9436 3063 2795 3086 287.8527864107 418.265413789217 436.4056773666 129.2027178883 113.746710275 130.8494655354 5.47478146000262e-07 -1.50064759379455 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-129, isoform a {ECO:0000313|EMBL:CAA92826.1} OS=Caenorhabditis elegans PE=1 SV=1 R General function prediction only Protein COL-129 [Caenorhabditis elegans] clec-42 gene39871 463 623 295 1626 1502 1735 16.0191 20.787 9.7646 54.344 49.4816 58.2346 3.79716198198523e-21 1.80362029791758 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms CUB domain;; Lectin C-type domain Protein CLEC-42 {ECO:0000313|EMBL:CAB04128.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CLEC-42 [Caenorhabditis elegans] ugt-41 gene35225 360 388 367 834 851 1132 15.26316 16.81122 15.99416 40.39577 42.00191 55.3097 8.17860547666124e-08 1.32349749960286 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-41 {ECO:0000313|EMBL:CCD69125.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein UGT-41 [Caenorhabditis elegans] T26H5.9 gene38712 115 105 78 285 178 311 798.676 745.862 607.136 2284.59 2518.51 3440.42 0.00130876269101204 1.36305794876441 up -- -- -- -- -- -- -- -- Protein T26H5.9, isoform a {ECO:0000313|EMBL:CAI79217.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein T26H5.9 [Caenorhabditis elegans] fmo-2 gene19438 274 318 519 2592 2695 2815 11.1974 13.0486 21.0552 108.887 115.57 129.493 1.43067435394137e-52 2.8514541205032 up [P] Inorganic ion transport and metabolism Molecular Function: N,N-dimethylaniline monooxygenase activity (GO:0004499);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; K00485|0|cel:CELE_K08C7.5|fmo-2; Protein FMO-2; K00485 dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] (A) Drug metabolism - cytochrome P450 (ko00982) [Q] Secondary metabolites biosynthesis, transport and catabolism Flavin-binding monooxygenase-like;; Pyridine nucleotide-disulphide oxidoreductase;; L-lysine 6-monooxygenase (NADPH-requiring);; Pyridine nucleotide-disulphide oxidoreductase;; NAD(P)-binding Rossmann-like domain;; Pyridine nucleotide-disulphide oxidoreductase Dimethylaniline monooxygenase [N-oxide-forming] {ECO:0000256|PIRNR:PIRNR000332} OS=Caenorhabditis elegans PE=2 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein FMO-2 [Caenorhabditis elegans] sodh-2 gene37246 238 305 259 86 61 59 13.91488 17.80181 14.60069 5.04598 3.5899 3.56482 1.63770741933496e-13 -1.97533606356058 down [R] General function prediction only Biological Process: oxidation-reduction process (GO:0055114);; K13953|0|cel:CELE_K12G11.4|sodh-2; Protein SODH-2; K13953 alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] (A) Glycolysis / Gluconeogenesis (ko00010);; Fatty acid degradation (ko00071);; Tyrosine metabolism (ko00350);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Degradation of aromatic compounds (ko01220) [Q] Secondary metabolites biosynthesis, transport and catabolism Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase CBN-SODH-2 protein {ECO:0000313|EMBL:EGT60304.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein SODH-2 [Caenorhabditis elegans] Y57G11C.6 gene24554 67 100 103 30 48 47 2.483158 3.71248 3.82453 1.163899 1.795044 1.80667 0.00276573991025465 -1.12413043672372 down -- -- Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase Protein Y57G11C.6 {ECO:0000313|EMBL:CAB16508.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein Y57G11C.6 [Caenorhabditis elegans] W06H8.2 gene34819 214 195 171 3768 3378 3642 9.232119 8.31096 6.983648 160.8775 145.79643 161.5054 1.40448020515422e-100 4.20309482359981 up [C] Energy production and conversion Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [CR] Energy production and conversion;; General function prediction only NADH:flavin oxidoreductase / NADH oxidase family Protein W06H8.2 {ECO:0000313|EMBL:CCD72164.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein W06H8.2 [Caenorhabditis elegans] oac-54 gene7559 7829 8143 5683 25358 23863 25411 305.7144 318.3916 219.44761 979.1499 925.1809 982.8332 1.51930355929207e-21 1.77156764389626 up -- -- Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [R] General function prediction only Acyltransferase family Protein OAC-54 {ECO:0000313|EMBL:CAA92707.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein OAC-54 [Caenorhabditis elegans] nhr-193 gene39147 100 68 83 170 184 185 5.0803544222 3.2461509866 4.341443236 9.16365070595649 10.023304777 10.299744 0.00033489151611233 1.08794511029144 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) Protein NHR-193 {ECO:0000313|EMBL:CAB05534.2} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein NHR-193 [Caenorhabditis elegans] F53H2.1 gene40566 115 98 61 220 222 201 2.77143400019361 2.243012 1.51547500300004 5.3175297259 5.4538460895 5.156403866 2.00030809251188e-05 1.21700630859793 up -- -- -- -- -- -- -- Protein of unknown function (DUF713) Protein F53H2.1 {ECO:0000313|EMBL:CAB63203.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F53H2.1 [Caenorhabditis elegans] nhr-21 gene6888 901 736 1063 3600 3111 3343 37.8085628571359 30.9302790353903 44.07833515 154.970775256647 130.373322523426 145.623508105832 1.4613636398625e-25 1.88153099009679 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Protein NHR-21, isoform e {ECO:0000313|EMBL:CCD69793.1} OS=Caenorhabditis elegans PE=3 SV=1 E Amino acid transport and metabolism Protein NHR-21, isoform e [Caenorhabditis elegans] H06I04.5 gene10091 88 137 136 55 68 54 1.20918750000003 1.89229140000739 1.918120413264 0.822959326159204 0.9406106146334 0.816354000000018 0.00244319521508534 -1.04189318206518 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; -- -- -- -- Protein-tyrosine phosphatase;; Domain of unknown function;; Dual specificity phosphatase, catalytic domain Protein H06I04.5 {ECO:0000313|EMBL:CCD72256.1} OS=Caenorhabditis elegans PE=4 SV=4 R General function prediction only Protein H06I04.5 [Caenorhabditis elegans] Y40H4A.2 gene38351 44 39 38 15 17 14 3.50757 3.09572 3.05697 1.23055 1.4607 1.20301 0.00403283203741885 -1.40947903948327 down [T] Signal transduction mechanisms Molecular Function: hydrolase activity (GO:0016787);; K01090|0|cel:CELE_Y40H4A.2|Y40H4A.2; Protein Y40H4A.2; K01090 protein phosphatase [EC:3.1.3.16] (A) -- [TR] Signal transduction mechanisms;; General function prediction only Calcineurin-like phosphoesterase Protein Y40H4A.2 {ECO:0000313|EMBL:CAA22302.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein Y40H4A.2 [Caenorhabditis elegans] T22B2.6 gene41911 118 87 73 38 45 44 24.2746 16.7108 14.0746 7.65321 9.96053 9.05346 0.00207038452833578 -1.14410495464774 down -- -- -- -- -- -- -- -- Protein T22B2.6 {ECO:0000313|EMBL:CCD71428.1} OS=Caenorhabditis elegans PE=4 SV=2 A RNA processing and modification Protein T22B2.6 [Caenorhabditis elegans] col-63 gene2074 2071 2214 2240 651 696 533 83.0829 89.3976 90.2385 25.8552 25.4813 20.9976 1.12224937986677e-22 -1.80952522663691 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-63 {ECO:0000313|EMBL:CAB03513.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-63 [Caenorhabditis elegans] Y52E8A.3 gene5699 285 255 132 83 54 69 88.3397 72.9853 39.5785 25.1619 18.8776 22.3024 0.00453800547569557 -1.71963144088293 down [OC] Posttranslational modification, protein turnover, chaperones;; Energy production and conversion Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: cell redox homeostasis (GO:0045454);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [R] General function prediction only Thioredoxin-like;; AhpC/TSA family;; Thioredoxin;; Redoxin;; Thioredoxin-like domain;; SCO1/SenC;; Thioredoxin Protein Y52E8A.3 {ECO:0000313|EMBL:CCD62413.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein Y52E8A.3 [Caenorhabditis elegans] K01A2.4 gene4291 71 116 79 183 240 175 6.98124 10.17081 9.02515 15.38669 25.47162 13.156540015 0.0001106354709592 1.1559621565491 up -- -- -- -- -- -- -- -- Protein K01A2.4 {ECO:0000313|EMBL:CCD61953.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein K01A2.4 [Caenorhabditis elegans] ugt-40 gene35214 352 344 261 834 665 864 11.6664972105 11.17211400022 8.62862900000009 25.075985 21.86642 28.26625 1.5114742493741e-09 1.29020357865065 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-40 {ECO:0000313|EMBL:CCD69119.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein UGT-40 [Caenorhabditis elegans] Y9D1A.1 gene6915 145 101 106 201 292 244 4.3111 3.20536 3.34848 6.17802 9.33292 8.08302 0.000300264901732872 1.05205088264713 up -- -- -- -- -- -- -- -- Protein Y9D1A.1 {ECO:0000313|EMBL:CCD68346.1} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein Y9D1A.1 [Caenorhabditis elegans] alh-2 gene33323 7 5 6 45 26 37 0.2411554902 0.201250685 0.221404958819 1.6209725963 0.921233517 1.2869528443 1.31205990300277e-06 2.56951886665937 up [C] Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [C] Energy production and conversion Aldehyde dehydrogenase family Protein ALH-2 {ECO:0000313|EMBL:CCD72650.1} OS=Caenorhabditis elegans PE=3 SV=3 R General function prediction only Protein ALH-2 [Caenorhabditis elegans] msp-49 gene5997 56 110 102 34 40 32 27.6831 48.0192 47.0718 16.1764 22.85 16.9141 0.00827437706301252 -1.35158405931668 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein MSP-49 [Caenorhabditis elegans] ZK616.65 gene15486 55 56 69 24 25 34 1.5433087 1.553122627 1.920087643 0.66839078 0.67473497 0.9241077107 0.00873320352731098 -1.13093270061053 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase Protein ZK616.65, isoform b {ECO:0000313|EMBL:CDK13607.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms ZK616.65, isoform a [Caenorhabditis elegans] gcy-5 gene7951 25 32 13 74 88 56 0.3889602 0.5248379 0.2020084 1.1137085 1.185932 0.8575042 4.73359522296171e-05 1.62641454693081 up [T] Signal transduction mechanisms Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; K01769|0|cel:CELE_ZK970.6|gcy-5; Protein GCY-5; K01769 guanylate cyclase, other [EC:4.6.1.2] (A) Purine metabolism (ko00230) [T] Signal transduction mechanisms Adenylate and Guanylate cyclase catalytic domain;; Receptor family ligand binding region;; Protein tyrosine kinase;; Protein kinase domain Guanylate cyclase {ECO:0000256|RuleBase:RU003431} OS=Caenorhabditis elegans PE=3 SV=1 E Amino acid transport and metabolism Protein GCY-5 [Caenorhabditis elegans] col-161 gene37861 3486 3764 3196 1780 1542 1532 202.155 204.894 176.119 95.9624 83.5053 83.2832 1.01326871550807e-09 -1.11978642117168 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-161 {ECO:0000313|EMBL:CAB02849.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein COL-161 [Caenorhabditis elegans] C15A11.7 gene1863 1038 1154 1011 489 417 477 70.19585 76.89909 67.78084 32.8174 28.55859 33.28994 1.70141515466227e-09 -1.22560052471965 down -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- -- -- Sulfite exporter TauE/SafE Protein C15A11.7, isoform a {ECO:0000313|EMBL:CAB01964.1} OS=Caenorhabditis elegans PE=4 SV=2 W Extracellular structures Protein C15A11.7, isoform a [Caenorhabditis elegans] nspc-10 gene45017 560 593 638 314 216 239 1113.364 1043.365 1189.28 605.882 627.654 551.4873 4.03747528747109e-08 -1.23461890982838 down -- -- -- -- -- -- -- -- Protein NSPC-10 {ECO:0000313|EMBL:CAD54145.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein NSPC-10 [Caenorhabditis elegans] Y51B9A.6 gene7631 75 57 60 115 146 133 4.003012 3.031964022 3.1544507 6.13365693 8.364260783 7.736401623 0.00235115307095826 1.02296372730539 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein Y51B9A.6, isoform a {ECO:0000313|EMBL:CAA19541.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y51B9A.6, isoform a [Caenorhabditis elegans] snf-5 gene8796 283 362 433 160 170 201 8.46492 10.7899 12.9675 4.77984 5.40996 6.46502 0.000543600624034467 -1.03561888489091 down -- -- Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; K05038|0|cel:CELE_Y46G5A.30|snf-5; Protein SNF-5; K05038 solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14 (A) -- [T] Signal transduction mechanisms Sodium:neurotransmitter symporter family Transporter {ECO:0000256|RuleBase:RU003732} OS=Caenorhabditis elegans PE=2 SV=1 I Lipid transport and metabolism Protein SNF-5 [Caenorhabditis elegans] C06B8.2 gene38728 125 97 118 387 328 306 5.884515508 4.2092627 5.18994300018003 17.905204 16.0510088000014 14.3603029003655 3.85861470955915e-10 1.57124903738937 up -- -- -- -- -- -- -- Protein of unknown function (DUF1647) Protein C06B8.2, isoform c {ECO:0000313|EMBL:CBL87047.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein C06B8.2, isoform c [Caenorhabditis elegans] C50F2.5 gene788 52 71 76 34 17 28 3.08032 4.18294 4.44576 2.05294 1.07992 1.84003 0.00106260529180819 -1.34771267366652 down -- -- Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- -- -- Protein-tyrosine phosphatase Protein C50F2.5 {ECO:0000313|EMBL:CCD67772.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C50F2.5 [Caenorhabditis elegans]