########################################################################################################### # # ENSG00000245532 NEAT1 # ########################################################################################################### GOID Ontology Pvalue FDR Term 1 GO:0006590 BP 0.00e+00 0.00e+00 thyroid hormone generation 2 GO:0071681 BP 0.00e+00 0.00e+00 cellular response to indole-3-methanol 3 GO:0042446 BP 1.63e-06 5.34e-04 hormone biosynthetic process 4 GO:0035635 BP 1.63e-06 1.41e-03 entry of bacterium into host cell 5 GO:0042026 BP 4.78e-06 1.51e-03 protein refolding 6 GO:0042403 BP 7.72e-06 1.90e-03 thyroid hormone metabolic process 7 GO:0070830 BP 1.92e-05 9.68e-03 bicellular tight junction assembly 8 GO:0006820 BP 8.07e-05 1.59e-02 anion transport 9 GO:0030878 BP 1.22e-04 2.01e-02 thyroid gland development 10 GO:0045717 BP 1.55e-04 2.18e-02 negative regulation of fatty acid biosynthetic process 11 GO:0007016 BP 1.04e-04 2.47e-02 cytoskeletal anchoring at plasma membrane --------------------------------------------------------------------------------------------------- GOID Ontology Pvalue FDR Term 1 GO:0015301 MF 8.07e-05 2.57e-02 anion:anion antiporter activity 2 GO:0004888 MF 1.69e-04 2.69e-02 transmembrane signaling receptor activity 3 GO:0003995 MF 3.94e-04 3.14e-02 acyl-CoA dehydrogenase activity 4 GO:0015106 MF 3.94e-04 3.14e-02 bicarbonate transmembrane transporter activity 5 GO:0043236 MF 1.22e-04 3.36e-02 laminin binding ########################################################################################################### # # ENSG00000230061 TRPM2-AS # ########################################################################################################### GOID Ontology Pvalue FDR Term 1 GO:0007186 BP 2.53e-08 1.97e-05 G-protein coupled receptor signaling pathway 2 GO:0035308 BP 2.42e-08 2.22e-05 negative regulation of protein dephosphorylation 3 GO:0071805 BP 5.35e-06 2.08e-03 potassium ion transmembrane transport 4 GO:0034629 BP 1.91e-05 8.81e-03 cellular protein complex localization 5 GO:0007603 BP 3.79e-05 9.81e-03 phototransduction, visible light 6 GO:0007601 BP 2.29e-05 1.30e-02 visual perception 7 GO:0048167 BP 4.55e-05 1.40e-02 regulation of synaptic plasticity 8 GO:0006811 BP 1.59e-04 2.47e-02 ion transport 9 GO:0007218 BP 1.38e-04 2.47e-02 neuropeptide signaling pathway 10 GO:0006813 BP 2.03e-04 2.63e-02 potassium ion transport 11 GO:0016192 BP 1.40e-04 3.21e-02 vesicle-mediated transport 12 GO:0050953 BP 1.55e-04 3.54e-02 sensory perception of light stimulus 13 GO:0007165 BP 3.76e-04 4.02e-02 signal transduction 14 GO:0019222 BP 4.66e-04 4.02e-02 regulation of metabolic process 15 GO:0042490 BP 4.66e-04 4.02e-02 mechanoreceptor differentiation 16 GO:0014050 BP 4.66e-04 4.56e-02 negative regulation of glutamate secretion 17 GO:0034316 BP 4.66e-04 4.56e-02 negative regulation of Arp2/3 complex-mediated actin nucleation 18 GO:2000969 BP 4.66e-04 4.56e-02 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 19 GO:0007399 BP 8.33e-04 4.97e-02 nervous system development 20 GO:0034765 BP 6.80e-04 4.97e-02 regulation of ion transmembrane transport 21 GO:0050896 BP 8.04e-04 4.97e-02 response to stimulus ----------------------------------------------------------------------------------------------------------------------------------------------------------- GOID Ontology Pvalue FDR Term 1 GO:0004930 MF 1.70e-09 4.83e-07 G-protein coupled receptor activity 2 GO:0004871 MF 5.83e-08 8.31e-06 signal transducer activity 3 GO:0003924 MF 1.26e-06 3.97e-04 GTPase activity 4 GO:0005249 MF 1.52e-05 1.44e-03 voltage-gated potassium channel activity 5 GO:0005525 MF 1.07e-05 1.68e-03 GTP binding 6 GO:0005267 MF 4.70e-05 3.35e-03 potassium channel activity 7 GO:0005216 MF 1.49e-04 8.47e-03 ion channel activity 8 GO:0047555 MF 2.99e-04 1.42e-02 3',5'-cyclic-GMP phosphodiesterase activity 9 GO:0005215 MF 5.18e-05 1.43e-02 transporter activity 10 GO:0005244 MF 4.13e-04 1.68e-02 voltage-gated ion channel activity 11 GO:0003910 MF 9.24e-04 3.24e-02 DNA ligase (ATP) activity 12 GO:0004864 MF 5.82e-04 3.24e-02 protein phosphatase inhibitor activity 13 GO:0016409 MF 7.93e-04 3.24e-02 palmitoyltransferase activity 14 GO:0019001 MF 6.40e-04 3.24e-02 guanyl nucleotide binding 15 GO:0019212 MF 9.24e-04 3.24e-02 phosphatase inhibitor activity 16 GO:0032190 MF 4.66e-04 3.24e-02 acrosin binding 17 GO:0070300 MF 6.40e-04 3.24e-02 phosphatidic acid binding 18 GO:0031683 MF 1.38e-03 4.36e-02 G-protein beta/gamma-subunit complex binding 19 GO:0008200 MF 1.53e-03 4.38e-02 ion channel inhibitor activity 20 GO:0000166 MF 1.74e-03 4.56e-02 nucleotide binding ########################################################################################################### # # ENSG00000265369 PCAT18 # ########################################################################################################### GOID Ontology Pvalue FDR Term 1 GO:0006590 BP 3.67e-12 3.36e-09 thyroid hormone generation 2 GO:0006629 BP 3.67e-07 2.97e-04 lipid metabolic process 3 GO:0008152 BP 1.17e-05 4.75e-03 metabolic process 4 GO:0007031 BP 5.05e-05 1.02e-02 peroxisome organization 5 GO:0009083 BP 3.90e-05 1.02e-02 branched-chain amino acid catabolic process 6 GO:0006631 BP 6.99e-05 1.13e-02 fatty acid metabolic process 7 GO:0055114 BP 1.78e-04 2.40e-02 oxidation-reduction process 8 GO:0006820 BP 8.07e-05 3.04e-02 anion transport 9 GO:0008544 BP 1.70e-04 3.04e-02 epidermis development 10 GO:0030878 BP 1.22e-04 3.04e-02 thyroid gland development 11 GO:0042446 BP 1.55e-04 3.04e-02 hormone biosynthetic process 12 GO:0045717 BP 1.55e-04 3.04e-02 negative regulation of fatty acid biosynthetic process 13 GO:0001523 BP 5.24e-04 3.86e-02 retinoid metabolic process 14 GO:0006694 BP 5.24e-04 3.86e-02 steroid biosynthetic process 15 GO:0033540 BP 3.94e-04 3.86e-02 fatty acid beta-oxidation using acyl-CoA oxidase 16 GO:0045329 BP 4.66e-04 3.86e-02 carnitine biosynthetic process 17 GO:0045541 BP 4.66e-04 3.86e-02 negative regulation of cholesterol biosynthetic process 18 GO:0021983 BP 2.91e-04 4.45e-02 pituitary gland development 19 GO:0003382 BP 5.08e-04 4.54e-02 epithelial cell morphogenesis 20 GO:0048562 BP 4.66e-04 4.54e-02 embryonic organ morphogenesis 21 GO:0060512 BP 4.66e-04 4.54e-02 prostate gland morphogenesis 22 GO:0071107 BP 4.66e-04 4.54e-02 response to parathyroid hormone 23 GO:0071681 BP 4.66e-04 4.54e-02 cellular response to indole-3-methanol 24 GO:0006473 BP 1.04e-04 4.83e-02 protein acetylation ------------------------------------------------------------------------------------------------------- GOID Ontology Pvalue FDR Term 1 GO:0016491 MF 3.84e-05 9.79e-03 oxidoreductase activity 2 GO:0015301 MF 8.07e-05 2.63e-02 anion:anion antiporter activity 3 GO:0015020 MF 2.11e-04 2.69e-02 glucuronosyltransferase activity 4 GO:0003995 MF 3.94e-04 4.29e-02 acyl-CoA dehydrogenase activity 5 GO:0015106 MF 3.94e-04 4.29e-02 bicarbonate transmembrane transporter activity 6 GO:0016758 MF 5.12e-04 4.35e-02 transferase activity, transferring hexosyl groups 7 GO:0016874 MF 7.41e-04 4.72e-02 ligase activity ########################################################################################################### # # ENSG00000245750 PCAT29 # ########################################################################################################### GOID Ontology Pvalue FDR Term 1 GO:0050896 BP 3.31e-08 2.80e-05 response to stimulus 2 GO:0006351 BP 4.11e-07 1.62e-04 transcription, DNA-templated 3 GO:0006355 BP 3.22e-07 1.62e-04 regulation of transcription, DNA-templated 4 GO:0008584 BP 3.64e-06 1.53e-03 male gonad development 5 GO:0071371 BP 1.91e-05 4.04e-03 cellular response to gonadotropin stimulus 6 GO:2000020 BP 1.91e-05 4.04e-03 positive regulation of male gonad development 7 GO:0045954 BP 1.58e-05 4.14e-03 positive regulation of natural killer cell mediated cytotoxicity 8 GO:0030325 BP 3.90e-05 6.59e-03 adrenal gland development 9 GO:0043401 BP 5.14e-05 7.07e-03 steroid hormone mediated signaling pathway 10 GO:0050911 BP 5.86e-05 7.07e-03 detection of chemical stimulus involved in sensory perception of smell 11 GO:0050909 BP 7.12e-05 7.52e-03 sensory perception of taste 12 GO:0007186 BP 9.65e-05 8.44e-03 G-protein coupled receptor signaling pathway 13 GO:0008585 BP 9.99e-05 8.44e-03 female gonad development 14 GO:0071044 BP 6.57e-05 1.29e-02 histone mRNA catabolic process 15 GO:0007608 BP 1.96e-04 1.51e-02 sensory perception of smell 16 GO:0050870 BP 9.99e-05 1.57e-02 positive regulation of T cell activation 17 GO:0045893 BP 3.42e-04 2.69e-02 positive regulation of transcription, DNA-templated 18 GO:0051891 BP 4.66e-04 3.28e-02 positive regulation of cardioblast differentiation 19 GO:0048856 BP 5.08e-04 3.38e-02 anatomical structure development 20 GO:0007275 BP 5.12e-04 3.60e-02 multicellular organism development 21 GO:0007165 BP 7.46e-04 4.50e-02 signal transduction 22 GO:0009952 BP 7.46e-04 4.50e-02 anterior/posterior pattern specification 23 GO:0035239 BP 9.24e-04 4.99e-02 tube morphogenesis ------------------------------------------------------------------------------------------------------------------------------------------------ GOID Ontology Pvalue FDR Term 1 GO:0003676 MF 9.31e-07 2.57e-04 nucleic acid binding 2 GO:0003700 MF 3.41e-06 4.14e-04 transcription factor activity, sequence-specific DNA binding 3 GO:0043565 MF 1.74e-06 4.14e-04 sequence-specific DNA binding 4 GO:0003677 MF 3.47e-06 4.78e-04 DNA binding 5 GO:0003707 MF 3.26e-05 1.59e-03 steroid hormone receptor activity 6 GO:0004930 MF 2.24e-05 1.83e-03 G-protein coupled receptor activity 7 GO:0004984 MF 5.86e-05 2.87e-03 olfactory receptor activity 8 GO:0004879 MF 7.12e-05 2.88e-03 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding 9 GO:0000981 MF 9.09e-05 3.18e-03 RNA polymerase II transcription factor activity, sequence-specific DNA binding 10 GO:0005496 MF 2.11e-04 6.45e-03 steroid binding 11 GO:0001227 MF 7.66e-05 7.05e-03 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding 12 GO:0030284 MF 4.66e-04 1.12e-02 estrogen receptor activity 13 GO:0004871 MF 4.34e-04 1.14e-02 signal transducer activity 14 GO:0033038 MF 9.67e-04 2.00e-02 bitter taste receptor activity 15 GO:0008526 MF 1.53e-03 2.62e-02 phosphatidylinositol transporter activity 16 GO:0008289 MF 2.44e-03 4.56e-02 lipid binding ########################################################################################################### # # ENSG00000224087 POTEF-AS1 # ########################################################################################################### GOID Ontology Pvalue FDR Term 1 GO:0061760 BP 0.00e+00 0.00e+00 antifungal innate immune response 2 GO:0050911 BP 3.84e-42 7.61e-40 detection of chemical stimulus involved in sensory perception of smell 3 GO:0007608 BP 1.69e-40 2.23e-38 sensory perception of smell 4 GO:0050896 BP 6.49e-32 6.42e-30 response to stimulus 5 GO:0007186 BP 2.06e-20 1.63e-18 G-protein coupled receptor signaling pathway 6 GO:0042742 BP 5.48e-12 3.62e-10 defense response to bacterium 7 GO:0006952 BP 4.25e-10 2.40e-08 defense response 8 GO:0007165 BP 8.14e-08 4.03e-06 signal transduction 9 GO:0050907 BP 1.16e-07 5.09e-06 detection of chemical stimulus involved in sensory perception 10 GO:0006346 BP 8.21e-07 3.25e-05 methylation-dependent chromatin silencing 11 GO:0031424 BP 1.95e-06 6.97e-05 keratinization 12 GO:0050829 BP 2.11e-06 6.97e-05 defense response to Gram-negative bacterium 13 GO:0010466 BP 1.28e-05 3.89e-04 negative regulation of peptidase activity 14 GO:0010951 BP 1.02e-04 2.88e-03 negative regulation of endopeptidase activity 15 GO:0007586 BP 4.23e-06 3.51e-03 digestion 16 GO:0042178 BP 7.72e-06 3.51e-03 xenobiotic catabolic process 17 GO:0070527 BP 4.39e-06 3.63e-03 platelet aggregation 18 GO:0007044 BP 7.72e-06 3.66e-03 cell-substrate junction assembly 19 GO:0071300 BP 1.36e-05 4.31e-03 cellular response to retinoic acid 20 GO:0045087 BP 2.47e-04 6.53e-03 innate immune response 21 GO:0042633 BP 2.99e-04 7.39e-03 hair cycle 22 GO:0042733 BP 5.14e-05 9.03e-03 embryonic digit morphogenesis 23 GO:1901687 BP 5.05e-05 9.03e-03 glutathione derivative biosynthetic process 24 GO:0045596 BP 4.37e-04 9.62e-03 negative regulation of cell differentiation 25 GO:0048665 BP 5.08e-04 1.06e-02 neuron fate specification 26 GO:0045777 BP 5.05e-05 1.08e-02 positive regulation of blood pressure 27 GO:0007275 BP 9.14e-05 1.24e-02 multicellular organism development 28 GO:0016573 BP 9.32e-04 1.76e-02 histone acetylation 29 GO:0099601 BP 9.24e-04 1.76e-02 regulation of neurotransmitter receptor activity 30 GO:0006936 BP 2.51e-04 3.44e-02 muscle contraction 31 GO:0007389 BP 3.29e-04 3.44e-02 pattern specification process 32 GO:0030850 BP 5.08e-04 3.44e-02 prostate gland development 33 GO:0060157 BP 4.66e-04 3.44e-02 urinary bladder development 34 GO:0072207 BP 4.66e-04 3.44e-02 metanephric epithelium development 35 GO:0090131 BP 4.66e-04 3.44e-02 mesenchyme migration 36 GO:1901318 BP 4.66e-04 3.44e-02 negative regulation of flagellated sperm motility 37 GO:0007195 BP 2.27e-03 3.60e-02 adenylate cyclase-inhibiting dopamine receptor signaling pathway 38 GO:0007283 BP 2.25e-03 3.60e-02 spermatogenesis 39 GO:0043266 BP 2.27e-03 3.60e-02 regulation of potassium ion transport 40 GO:0070268 BP 2.10e-03 3.60e-02 cornification 41 GO:0050830 BP 3.16e-03 4.81e-02 defense response to Gram-positive bacterium 42 GO:0060527 BP 9.24e-04 4.95e-02 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 43 GO:2000288 BP 9.24e-04 4.95e-02 positive regulation of myoblast proliferation ----------------------------------------------------------------------------------------------------------------------------------------- GOID Ontology Pvalue FDR Term 1 GO:0004984 MF 3.84e-42 6.11e-40 olfactory receptor activity 2 GO:0004930 MF 4.26e-25 3.39e-23 G-protein coupled receptor activity 3 GO:0004871 MF 9.88e-20 5.24e-18 signal transducer activity 4 GO:0005549 MF 3.22e-08 1.28e-06 odorant binding 5 GO:0030414 MF 1.19e-05 3.78e-04 peptidase inhibitor activity 6 GO:0043565 MF 1.74e-06 5.26e-04 sequence-specific DNA binding 7 GO:0008327 MF 3.90e-05 1.03e-03 methyl-CpG binding 8 GO:0004867 MF 1.04e-04 2.36e-03 serine-type endopeptidase inhibitor activity 9 GO:0000981 MF 1.60e-05 2.43e-03 RNA polymerase II transcription factor activity, sequence-specific DNA binding 10 GO:0001530 MF 1.77e-04 3.52e-03 lipopolysaccharide binding 11 GO:0043295 MF 1.04e-04 5.96e-03 glutathione binding 12 GO:0004364 MF 1.48e-04 7.05e-03 glutathione transferase activity 13 GO:0030548 MF 4.66e-04 7.41e-03 acetylcholine receptor regulator activity 14 GO:0031727 MF 4.66e-04 7.41e-03 CCR2 chemokine receptor binding 15 GO:0004869 MF 5.82e-04 8.42e-03 cysteine-type endopeptidase inhibitor activity 16 GO:0004993 MF 6.40e-04 8.49e-03 G-protein coupled serotonin receptor activity 17 GO:0030594 MF 7.93e-04 9.70e-03 neurotransmitter receptor activity 18 GO:0001591 MF 9.24e-04 1.05e-02 dopamine neurotransmitter receptor activity, coupled via Gi/Go 19 GO:0004402 MF 1.55e-03 1.64e-02 histone acetyltransferase activity 20 GO:0003779 MF 3.73e-04 1.89e-02 actin binding 21 GO:0005198 MF 2.08e-03 1.95e-02 structural molecule activity 22 GO:0004645 MF 4.66e-04 2.02e-02 phosphorylase activity 23 GO:0005109 MF 5.82e-04 2.15e-02 frizzled binding 24 GO:0035240 MF 5.32e-03 4.70e-02 dopamine binding 25 GO:0008236 MF 1.88e-03 4.90e-02 serine-type peptidase activity ########################################################################################################### # # ENSG00000255717 SNHG1 # ########################################################################################################### GOID Ontology Pvalue FDR Term 1 GO:0006664 BP 0.00e+00 0.00e+00 glycolipid metabolic process 2 GO:0061087 BP 0.00e+00 0.00e+00 positive regulation of histone H3-K27 methylation 3 GO:0006614 BP 2.57e-17 3.38e-14 SRP-dependent cotranslational protein targeting to membrane 4 GO:0019083 BP 1.37e-15 8.99e-13 viral transcription 5 GO:0000184 BP 6.02e-15 2.63e-12 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 6 GO:0006413 BP 2.32e-14 7.61e-12 translational initiation 7 GO:0006351 BP 7.58e-14 1.60e-11 transcription, DNA-templated 8 GO:0006355 BP 7.68e-14 1.60e-11 regulation of transcription, DNA-templated 9 GO:0006364 BP 1.00e-10 2.63e-08 rRNA processing 10 GO:0006412 BP 6.26e-09 1.37e-06 translation 11 GO:0006397 BP 3.00e-08 2.97e-06 mRNA processing 12 GO:0008380 BP 3.21e-08 2.97e-06 RNA splicing 13 GO:0000398 BP 7.83e-07 5.94e-05 mRNA splicing, via spliceosome 14 GO:0006954 BP 2.42e-06 4.55e-04 inflammatory response 15 GO:0051607 BP 6.54e-06 1.07e-03 defense response to virus 16 GO:0000028 BP 7.44e-06 1.09e-03 ribosomal small subunit assembly 17 GO:0042274 BP 2.96e-05 1.76e-03 ribosomal small subunit biogenesis 18 GO:0006120 BP 1.74e-05 2.28e-03 mitochondrial electron transport, NADH to ubiquinone 19 GO:0032481 BP 2.25e-05 2.69e-03 positive regulation of type I interferon production 20 GO:0006915 BP 3.08e-05 3.11e-03 apoptotic process 21 GO:0070301 BP 4.60e-05 4.32e-03 cellular response to hydrogen peroxide 22 GO:0002376 BP 9.94e-05 6.84e-03 immune system process 23 GO:0032981 BP 8.59e-05 6.84e-03 mitochondrial respiratory chain complex I assembly 24 GO:0050862 BP 1.04e-04 6.84e-03 positive regulation of T cell receptor signaling pathway 25 GO:0060444 BP 1.04e-04 6.84e-03 branching involved in mammary gland duct morphogenesis 26 GO:0097191 BP 9.36e-05 6.84e-03 extrinsic apoptotic signaling pathway 27 GO:0010501 BP 1.37e-04 7.62e-03 RNA secondary structure unwinding 28 GO:0006611 BP 1.22e-04 7.64e-03 protein export from nucleus 29 GO:2001241 BP 1.55e-04 8.84e-03 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 30 GO:0008630 BP 1.94e-04 1.06e-02 intrinsic apoptotic signaling pathway in response to DNA damage 31 GO:0000245 BP 2.11e-04 1.10e-02 spliceosomal complex assembly 32 GO:0045087 BP 2.47e-04 1.25e-02 innate immune response 33 GO:0006122 BP 2.99e-04 1.40e-02 mitochondrial electron transport, ubiquinol to cytochrome c 34 GO:0051881 BP 2.91e-04 1.40e-02 regulation of mitochondrial membrane potential 35 GO:0043491 BP 3.38e-04 1.53e-02 protein kinase B signaling 36 GO:0006099 BP 3.90e-04 1.71e-02 tricarboxylic acid cycle 37 GO:0002082 BP 4.66e-04 1.75e-02 regulation of oxidative phosphorylation 38 GO:0006924 BP 4.66e-04 1.75e-02 activation-induced cell death of T cells 39 GO:0051344 BP 4.66e-04 1.75e-02 negative regulation of cyclic-nucleotide phosphodiesterase activity 40 GO:0090131 BP 4.66e-04 1.75e-02 mesenchyme migration 41 GO:1901727 BP 4.66e-04 1.75e-02 positive regulation of histone deacetylase activity 42 GO:0006405 BP 3.99e-04 1.85e-02 RNA export from nucleus 43 GO:0001570 BP 5.24e-04 1.91e-02 vasculogenesis 44 GO:0050921 BP 1.55e-04 1.92e-02 positive regulation of chemotaxis 45 GO:0000380 BP 5.08e-04 2.23e-02 alternative mRNA splicing, via spliceosome 46 GO:1902041 BP 6.40e-04 2.27e-02 regulation of extrinsic apoptotic signaling pathway via death domain receptors 47 GO:1902600 BP 7.34e-04 2.53e-02 hydrogen ion transmembrane transport 48 GO:0007182 BP 9.24e-04 2.76e-02 common-partner SMAD protein phosphorylation 49 GO:0045345 BP 9.24e-04 2.76e-02 positive regulation of MHC class I biosynthetic process 50 GO:0051101 BP 9.24e-04 2.76e-02 regulation of DNA binding 51 GO:0070383 BP 9.24e-04 2.76e-02 DNA cytosine deamination 52 GO:0071359 BP 9.24e-04 2.76e-02 cellular response to dsRNA 53 GO:2001269 BP 9.24e-04 2.76e-02 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 54 GO:0002548 BP 2.91e-04 3.09e-02 monocyte chemotaxis 55 GO:0022904 BP 1.16e-03 3.34e-02 respiratory electron transport chain 56 GO:0051092 BP 1.17e-03 3.34e-02 positive regulation of NF-kappaB transcription factor activity 57 GO:0000381 BP 8.33e-04 3.47e-02 regulation of alternative mRNA splicing, via spliceosome 58 GO:0043536 BP 1.38e-03 3.78e-02 positive regulation of blood vessel endothelial cell migration 59 GO:0048872 BP 1.38e-03 3.78e-02 homeostasis of number of cells 60 GO:0000122 BP 1.03e-03 4.03e-02 negative regulation of transcription from RNA polymerase II promoter 61 GO:0006406 BP 1.06e-03 4.03e-02 mRNA export from nucleus 62 GO:0045869 BP 1.53e-03 4.09e-02 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 63 GO:0008637 BP 1.63e-03 4.27e-02 apoptotic mitochondrial changes 64 GO:0009611 BP 1.74e-03 4.49e-02 response to wounding 65 GO:0071260 BP 1.86e-03 4.69e-02 cellular response to mechanical stimulus 66 GO:0012501 BP 1.90e-03 4.70e-02 programmed cell death 67 GO:0006396 BP 1.47e-03 4.78e-02 RNA processing 68 GO:0030218 BP 1.55e-03 4.78e-02 erythrocyte differentiation 69 GO:0030521 BP 1.55e-03 4.78e-02 androgen receptor signaling pathway 70 GO:0048025 BP 1.38e-03 4.78e-02 negative regulation of mRNA splicing, via spliceosome 71 GO:2001014 BP 1.53e-03 4.78e-02 regulation of skeletal muscle cell differentiation 72 GO:0001768 BP 9.24e-04 4.80e-02 establishment of T cell polarity 73 GO:0045627 BP 9.24e-04 4.80e-02 positive regulation of T-helper 1 cell differentiation 74 GO:2000107 BP 9.24e-04 4.80e-02 negative regulation of leukocyte apoptotic process 75 GO:0002903 BP 2.27e-03 4.89e-02 negative regulation of B cell apoptotic process 76 GO:0007184 BP 2.27e-03 4.89e-02 SMAD protein import into nucleus 77 GO:0021915 BP 2.03e-03 4.89e-02 neural tube development 78 GO:0034341 BP 2.19e-03 4.89e-02 response to interferon-gamma 79 GO:0042117 BP 2.27e-03 4.89e-02 monocyte activation 80 GO:0042775 BP 2.27e-03 4.89e-02 mitochondrial ATP synthesis coupled electron transport 81 GO:0045944 BP 2.15e-03 4.89e-02 positive regulation of transcription from RNA polymerase II promoter 82 GO:1990314 BP 2.27e-03 4.89e-02 cellular response to insulin-like growth factor stimulus 83 GO:0016239 BP 2.52e-03 4.93e-02 positive regulation of macroautophagy 84 GO:0030316 BP 2.52e-03 4.93e-02 osteoclast differentiation 85 GO:0032735 BP 2.52e-03 4.93e-02 positive regulation of interleukin-12 production 86 GO:0043065 BP 2.47e-03 4.93e-02 positive regulation of apoptotic process 87 GO:0050728 BP 2.38e-03 4.93e-02 negative regulation of inflammatory response -------------------------------------------------------------------------------------------------------------------------------------------------- GOID Ontology Pvalue FDR Term 1 GO:0003676 MF 7.01e-18 1.87e-15 nucleic acid binding 2 GO:0003735 MF 3.83e-12 1.22e-09 structural constituent of ribosome 3 GO:0003677 MF 2.81e-10 4.03e-08 DNA binding 4 GO:0003723 MF 7.02e-09 6.71e-07 RNA binding 5 GO:0051536 MF 2.98e-07 4.75e-05 iron-sulfur cluster binding 6 GO:0046872 MF 1.31e-06 7.51e-05 metal ion binding 7 GO:0003823 MF 1.16e-06 2.51e-04 antigen binding 8 GO:0034987 MF 1.95e-06 2.51e-04 immunoglobulin receptor binding 9 GO:0005515 MF 4.78e-06 5.09e-04 protein binding 10 GO:0008121 MF 1.91e-05 1.22e-03 ubiquinol-cytochrome-c reductase activity 11 GO:0019843 MF 7.12e-05 3.24e-03 rRNA binding 12 GO:0051539 MF 6.16e-05 3.24e-03 4 iron, 4 sulfur cluster binding 13 GO:0008270 MF 9.84e-05 5.23e-03 zinc ion binding 14 GO:0008137 MF 1.54e-04 6.16e-03 NADH dehydrogenase (ubiquinone) activity 15 GO:0008177 MF 4.66e-04 1.49e-02 succinate dehydrogenase (ubiquinone) activity 16 GO:0047184 MF 4.66e-04 1.49e-02 1-acylglycerophosphocholine O-acyltransferase activity 17 GO:0003700 MF 4.41e-04 1.55e-02 transcription factor activity, sequence-specific DNA binding 18 GO:0008186 MF 4.66e-04 1.55e-02 RNA-dependent ATPase activity 19 GO:0003729 MF 6.90e-04 2.00e-02 mRNA binding 20 GO:0001665 MF 9.24e-04 2.05e-02 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity 21 GO:0004004 MF 9.28e-04 2.05e-02 ATP-dependent RNA helicase activity 22 GO:0008474 MF 9.24e-04 2.05e-02 palmitoyl-(protein) hydrolase activity 23 GO:1990948 MF 9.24e-04 2.05e-02 ubiquitin ligase inhibitor activity 24 GO:0003841 MF 9.67e-04 2.57e-02 1-acylglycerol-3-phosphate O-acyltransferase activity 25 GO:0031491 MF 9.67e-04 2.57e-02 nucleosome binding 26 GO:0004386 MF 1.59e-03 3.05e-02 helicase activity 27 GO:0004439 MF 2.27e-03 3.62e-02 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 28 GO:0016790 MF 2.27e-03 3.62e-02 thiolester hydrolase activity 29 GO:0030628 MF 2.27e-03 3.62e-02 pre-mRNA 3'-splice site binding 30 GO:0051537 MF 1.63e-03 3.99e-02 2 iron, 2 sulfur cluster binding 31 GO:0043995 MF 3.16e-03 4.31e-02 histone acetyltransferase activity (H4-K5 specific) 32 GO:0043996 MF 3.16e-03 4.31e-02 histone acetyltransferase activity (H4-K8 specific) 33 GO:0046972 MF 3.16e-03 4.31e-02 histone acetyltransferase activity (H4-K16 specific) 34 GO:0003682 MF 3.55e-03 4.64e-02 chromatin binding 35 GO:0005031 MF 2.19e-03 4.83e-02 tumor necrosis factor-activated receptor activity 36 GO:0070181 MF 2.27e-03 4.83e-02 small ribosomal subunit rRNA binding ########################################################################################################### # # ENSG00000228288 PCAN-R1 # ########################################################################################################### GOID Ontology Pvalue FDR Term 1 GO:0007283 BP 5.74e-21 2.25e-18 spermatogenesis 2 GO:0007049 BP 4.87e-17 2.24e-14 cell cycle 3 GO:0051301 BP 2.06e-14 3.16e-12 cell division 4 GO:0007059 BP 1.71e-13 1.97e-11 chromosome segregation 5 GO:0051321 BP 1.18e-11 1.09e-09 meiotic cell cycle 6 GO:0000278 BP 3.22e-11 2.47e-09 mitotic cell cycle 7 GO:0007062 BP 1.70e-10 1.12e-08 sister chromatid cohesion 8 GO:0048240 BP 3.18e-09 4.15e-07 sperm capacitation 9 GO:0007129 BP 6.52e-09 6.39e-07 synapsis 10 GO:0007140 BP 8.67e-08 6.80e-06 male meiosis 11 GO:0007141 BP 3.53e-07 2.27e-05 male meiosis I 12 GO:0034502 BP 1.95e-06 9.55e-05 protein localization to chromosome 13 GO:0007130 BP 1.63e-06 1.91e-04 synaptonemal complex assembly 14 GO:0030154 BP 7.96e-06 3.12e-04 cell differentiation 15 GO:0007565 BP 9.74e-07 5.08e-04 female pregnancy 16 GO:0007340 BP 1.10e-05 6.35e-04 acrosome reaction 17 GO:0007094 BP 1.58e-05 8.07e-04 mitotic spindle assembly checkpoint 18 GO:0007339 BP 3.29e-05 1.17e-03 binding of sperm to zona pellucida 19 GO:0030198 BP 4.46e-06 1.55e-03 extracellular matrix organization 20 GO:0034501 BP 6.57e-05 1.72e-03 protein localization to kinetochore 21 GO:0008608 BP 3.79e-05 1.74e-03 attachment of spindle microtubules to kinetochore 22 GO:0007286 BP 3.30e-05 1.93e-03 spermatid development 23 GO:0010389 BP 5.11e-05 2.14e-03 regulation of G2/M transition of mitotic cell cycle 24 GO:0071168 BP 6.57e-05 2.33e-03 protein localization to chromatin 25 GO:0006302 BP 8.59e-05 2.82e-03 double-strand break repair 26 GO:0007088 BP 9.99e-05 3.06e-03 regulation of mitotic nuclear division 27 GO:0007338 BP 1.50e-04 3.57e-03 single fertilization 28 GO:0007342 BP 1.55e-04 3.57e-03 fusion of sperm to egg plasma membrane 29 GO:0051310 BP 1.55e-04 4.45e-03 metaphase plate congression 30 GO:0035036 BP 2.19e-04 4.77e-03 sperm-egg recognition 31 GO:0000086 BP 1.82e-04 4.93e-03 G2/M transition of mitotic cell cycle 32 GO:0042476 BP 1.92e-05 5.01e-03 odontogenesis 33 GO:0007064 BP 2.19e-04 5.44e-03 mitotic sister chromatid cohesion 34 GO:0007131 BP 2.48e-04 5.44e-03 reciprocal meiotic recombination 35 GO:0090307 BP 2.48e-04 5.44e-03 mitotic spindle assembly 36 GO:0048477 BP 2.91e-04 5.99e-03 oogenesis 37 GO:0030326 BP 3.26e-05 6.81e-03 embryonic limb morphogenesis 38 GO:0007076 BP 3.94e-04 7.89e-03 mitotic chromosome condensation 39 GO:0034587 BP 3.94e-04 7.89e-03 piRNA metabolic process 40 GO:0006880 BP 4.66e-04 7.94e-03 intracellular sequestering of iron ion 41 GO:0007144 BP 4.66e-04 7.94e-03 female meiosis I 42 GO:0042138 BP 4.66e-04 7.94e-03 meiotic DNA double-strand break formation 43 GO:0045143 BP 4.66e-04 7.94e-03 homologous chromosome segregation 44 GO:0046602 BP 4.66e-04 7.94e-03 regulation of mitotic centrosome separation 45 GO:0071459 BP 4.66e-04 7.94e-03 protein localization to chromosome, centromeric region 46 GO:0007080 BP 5.82e-04 9.57e-03 mitotic metaphase plate congression 47 GO:0030199 BP 6.16e-05 9.79e-03 collagen fibril organization 48 GO:0048048 BP 6.57e-05 9.79e-03 embryonic eye morphogenesis 49 GO:0030261 BP 6.40e-04 1.00e-02 chromosome condensation 50 GO:2000117 BP 6.40e-04 1.00e-02 negative regulation of cysteine-type endopeptidase activity 51 GO:0000079 BP 9.32e-04 1.34e-02 regulation of cyclin-dependent protein serine/threonine kinase activity 52 GO:0007051 BP 1.16e-03 1.57e-02 spindle organization 53 GO:0043046 BP 1.16e-03 1.57e-02 DNA methylation involved in gamete generation 54 GO:1903507 BP 1.15e-03 1.74e-02 negative regulation of nucleic acid-templated transcription 55 GO:0001503 BP 1.59e-04 1.77e-02 ossification 56 GO:0001649 BP 1.70e-04 1.77e-02 osteoblast differentiation 57 GO:0001833 BP 1.55e-04 1.77e-02 inner cell mass cell proliferation 58 GO:0001824 BP 1.38e-03 2.01e-02 blastocyst development 59 GO:0040016 BP 1.53e-03 2.01e-02 embryonic cleavage 60 GO:0003341 BP 6.59e-04 2.20e-02 cilium movement 61 GO:0006270 BP 5.82e-04 2.20e-02 DNA replication initiation 62 GO:0036158 BP 6.40e-04 2.20e-02 outer dynein arm assembly 63 GO:0000070 BP 2.19e-03 2.80e-02 mitotic sister chromatid segregation 64 GO:0051026 BP 2.27e-03 2.83e-02 chiasma assembly 65 GO:0006890 BP 2.52e-03 2.90e-02 retrograde vesicle-mediated transport, Golgi to ER 66 GO:0060021 BP 4.43e-04 3.04e-02 palate development 67 GO:0060023 BP 4.66e-04 3.04e-02 soft palate development 68 GO:0060591 BP 4.66e-04 3.04e-02 chondroblast differentiation 69 GO:1904888 BP 4.66e-04 3.04e-02 cranial skeletal system development 70 GO:2000543 BP 4.66e-04 3.04e-02 positive regulation of gastrulation 71 GO:0045835 BP 2.27e-03 3.07e-02 negative regulation of meiotic nuclear division 72 GO:0010923 BP 2.82e-03 3.17e-02 negative regulation of phosphatase activity 73 GO:0007019 BP 3.16e-03 3.30e-02 microtubule depolymerization 74 GO:0051256 BP 3.16e-03 3.30e-02 mitotic spindle midzone assembly 75 GO:0051315 BP 3.16e-03 3.30e-02 attachment of mitotic spindle microtubules to kinetochore 76 GO:0006260 BP 3.59e-03 3.59e-02 DNA replication 77 GO:0007018 BP 3.52e-03 3.59e-02 microtubule-based movement 78 GO:0016477 BP 6.82e-04 3.94e-02 cell migration 79 GO:0030574 BP 7.34e-04 3.94e-02 collagen catabolic process 80 GO:0032331 BP 7.93e-04 3.94e-02 negative regulation of chondrocyte differentiation 81 GO:0034446 BP 6.59e-04 3.94e-02 substrate adhesion-dependent cell spreading 82 GO:0048566 BP 7.93e-04 3.94e-02 embryonic digestive tract development 83 GO:0006312 BP 4.17e-03 4.08e-02 mitotic recombination 84 GO:0045141 BP 3.16e-03 4.12e-02 meiotic telomere clustering 85 GO:0032570 BP 9.32e-04 4.22e-02 response to progesterone 86 GO:0046881 BP 9.24e-04 4.22e-02 positive regulation of follicle-stimulating hormone secretion 87 GO:0051726 BP 4.42e-03 4.23e-02 regulation of cell cycle 88 GO:0002062 BP 1.04e-03 4.51e-02 chondrocyte differentiation 89 GO:0008283 BP 5.39e-03 4.51e-02 cell proliferation 90 GO:0010529 BP 5.32e-03 4.51e-02 negative regulation of transposition 91 GO:0019886 BP 5.26e-03 4.51e-02 antigen processing and presentation of exogenous peptide antigen via MHC class II 92 GO:0034080 BP 5.06e-03 4.51e-02 CENP-A containing nucleosome assembly 93 GO:0051382 BP 5.32e-03 4.51e-02 kinetochore assembly 94 GO:0072520 BP 5.32e-03 4.51e-02 seminiferous tubule development 95 GO:0007052 BP 5.60e-03 4.60e-02 mitotic spindle organization 96 GO:0002009 BP 1.16e-03 4.81e-02 morphogenesis of an epithelium 97 GO:0007155 BP 1.29e-03 4.81e-02 cell adhesion 98 GO:0043280 BP 1.28e-03 4.81e-02 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 99 GO:0097191 BP 1.28e-03 4.81e-02 extrinsic apoptotic signaling pathway ------------------------------------------------------------------------------------------------------------------------------------ GOID Ontology Pvalue FDR Term 1 GO:0005201 MF 5.32e-07 1.47e-04 extracellular matrix structural constituent 2 GO:0010997 MF 1.95e-06 3.86e-04 anaphase-promoting complex binding 3 GO:0005520 MF 8.07e-05 1.12e-02 insulin-like growth factor binding 4 GO:0050840 MF 1.77e-04 1.64e-02 extracellular matrix binding 5 GO:0005178 MF 2.67e-04 1.85e-02 integrin binding 6 GO:0005509 MF 6.15e-04 3.41e-02 calcium ion binding ########################################################################################################### # # ENSG00000231806 PCAN-R2 # ########################################################################################################### GOID Ontology Pvalue FDR Term 1 GO:0007283 BP 2.93e-10 1.57e-07 spermatogenesis 2 GO:0007062 BP 3.89e-07 2.38e-04 sister chromatid cohesion 3 GO:2000647 BP 1.95e-06 1.76e-03 negative regulation of stem cell proliferation 4 GO:0000070 BP 9.99e-05 1.22e-02 mitotic sister chromatid segregation 5 GO:0044458 BP 8.07e-05 1.22e-02 motile cilium assembly 6 GO:0051301 BP 9.46e-05 1.22e-02 cell division 7 GO:0060046 BP 6.57e-05 1.35e-02 regulation of acrosome reaction 8 GO:0007342 BP 1.55e-04 2.13e-02 fusion of sperm to egg plasma membrane 9 GO:0007093 BP 3.38e-04 2.30e-02 mitotic cell cycle checkpoint 10 GO:0007286 BP 3.09e-04 2.30e-02 spermatid development 11 GO:0021591 BP 2.99e-04 2.30e-02 ventricular system development 12 GO:0060271 BP 2.78e-04 2.30e-02 cilium morphogenesis 13 GO:0051294 BP 4.66e-04 3.84e-02 establishment of spindle orientation ------------------------------------------------------------------------------------------- for MF: [1] "could not find anything!" ########################################################################################################### # # ENSG00000214548 MEG3 # ########################################################################################################### GOID Ontology Pvalue FDR Term 1 GO:0007565 BP 1.28e-15 1.10e-12 female pregnancy 2 GO:0030198 BP 1.35e-12 6.87e-10 extracellular matrix organization 3 GO:0030574 BP 9.26e-13 6.87e-10 collagen catabolic process 4 GO:0031424 BP 2.65e-08 1.13e-05 keratinization 5 GO:0060397 BP 7.14e-08 2.04e-05 JAK-STAT cascade involved in growth hormone signaling pathway 6 GO:0022617 BP 1.00e-07 3.41e-05 extracellular matrix disassembly 7 GO:0035987 BP 2.31e-07 5.89e-05 endodermal cell differentiation 8 GO:0048048 BP 3.55e-07 7.25e-05 embryonic eye morphogenesis 9 GO:0046881 BP 1.95e-06 3.31e-04 positive regulation of follicle-stimulating hormone secretion 10 GO:0030199 BP 3.06e-06 3.90e-04 collagen fibril organization 11 GO:0070208 BP 2.90e-06 3.90e-04 protein heterotrimerization 12 GO:0070234 BP 1.95e-06 4.17e-04 positive regulation of T cell apoptotic process 13 GO:0007155 BP 4.86e-06 5.51e-04 cell adhesion 14 GO:0001541 BP 6.15e-06 6.27e-04 ovarian follicle development 15 GO:0007186 BP 3.68e-06 6.34e-04 G-protein coupled receptor signaling pathway 16 GO:0001501 BP 9.76e-06 9.05e-04 skeletal system development 17 GO:0015671 BP 7.44e-06 1.07e-03 oxygen transport 18 GO:0042060 BP 8.76e-06 1.08e-03 wound healing 19 GO:0070268 BP 5.52e-06 1.24e-03 cornification 20 GO:0001503 BP 1.90e-05 1.55e-03 ossification 21 GO:0071230 BP 1.98e-05 1.55e-03 cellular response to amino acid stimulus 22 GO:0007399 BP 2.70e-05 1.97e-03 nervous system development 23 GO:0007292 BP 3.90e-05 3.34e-03 female gamete generation 24 GO:0016486 BP 3.90e-05 3.34e-03 peptide hormone processing 25 GO:0030325 BP 3.90e-05 3.34e-03 adrenal gland development 26 GO:0050911 BP 5.86e-05 4.18e-03 detection of chemical stimulus involved in sensory perception of smell 27 GO:0007267 BP 5.08e-05 5.71e-03 cell-cell signaling 28 GO:0032725 BP 6.57e-05 6.57e-03 positive regulation of granulocyte macrophage colony-stimulating factor production 29 GO:0001890 BP 1.07e-04 7.03e-03 placenta development 30 GO:0032940 BP 1.04e-04 7.08e-03 secretion by cell 31 GO:0044267 BP 1.42e-04 9.07e-03 cellular protein metabolic process 32 GO:0006703 BP 1.55e-04 9.47e-03 estrogen biosynthetic process 33 GO:0001649 BP 1.70e-04 1.00e-02 osteoblast differentiation 34 GO:0043542 BP 1.77e-04 1.00e-02 endothelial cell migration 35 GO:0007608 BP 1.96e-04 1.12e-02 sensory perception of smell 36 GO:0043434 BP 2.69e-04 1.44e-02 response to peptide hormone 37 GO:0030540 BP 4.66e-04 1.81e-02 female genitalia development 38 GO:0033278 BP 4.66e-04 1.81e-02 cell proliferation in midbrain 39 GO:0060065 BP 3.94e-04 1.81e-02 uterus development 40 GO:0061370 BP 4.66e-04 1.81e-02 testosterone biosynthetic process 41 GO:0071248 BP 4.66e-04 1.81e-02 cellular response to metal ion 42 GO:0099054 BP 4.66e-04 1.81e-02 presynapse assembly 43 GO:0007165 BP 3.76e-04 1.83e-02 signal transduction 44 GO:0006694 BP 5.24e-04 1.95e-02 steroid biosynthetic process 45 GO:0042541 BP 4.66e-04 2.16e-02 hemoglobin biosynthetic process 46 GO:0071800 BP 4.66e-04 2.16e-02 podosome assembly 47 GO:1900747 BP 4.66e-04 2.16e-02 negative regulation of vascular endothelial growth factor signaling pathway 48 GO:0034446 BP 6.59e-04 2.80e-02 substrate adhesion-dependent cell spreading 49 GO:0043277 BP 6.40e-04 2.80e-02 apoptotic cell clearance 50 GO:0061038 BP 9.24e-04 2.85e-02 uterus morphogenesis 51 GO:0061312 BP 9.24e-04 2.85e-02 BMP signaling pathway involved in heart development 52 GO:0000413 BP 8.33e-04 3.37e-02 protein peptidyl-prolyl isomerization 53 GO:0001957 BP 9.24e-04 3.37e-02 intramembranous ossification 54 GO:0032964 BP 9.24e-04 3.37e-02 collagen biosynthetic process 55 GO:0048642 BP 9.24e-04 3.37e-02 negative regulation of skeletal muscle tissue development 56 GO:0002062 BP 1.04e-03 3.45e-02 chondrocyte differentiation 57 GO:0030154 BP 1.05e-03 3.45e-02 cell differentiation 58 GO:0043524 BP 1.02e-03 3.45e-02 negative regulation of neuron apoptotic process 59 GO:0008284 BP 1.21e-03 3.59e-02 positive regulation of cell proliferation 60 GO:0042326 BP 1.16e-03 3.71e-02 negative regulation of phosphorylation 61 GO:0006898 BP 1.23e-03 3.79e-02 receptor-mediated endocytosis 62 GO:0043687 BP 1.28e-03 3.83e-02 post-translational protein modification 63 GO:0010700 BP 1.53e-03 3.87e-02 negative regulation of norepinephrine secretion 64 GO:0021520 BP 1.53e-03 3.87e-02 spinal cord motor neuron cell fate specification 65 GO:0036465 BP 1.53e-03 3.87e-02 synaptic vesicle recycling 66 GO:0045026 BP 1.53e-03 3.87e-02 plasma membrane fusion 67 GO:0055009 BP 1.53e-03 3.87e-02 atrial cardiac muscle tissue morphogenesis 68 GO:0001960 BP 1.53e-03 4.05e-02 negative regulation of cytokine-mediated signaling pathway 69 GO:0045650 BP 1.53e-03 4.05e-02 negative regulation of macrophage differentiation 70 GO:0046426 BP 1.55e-03 4.05e-02 negative regulation of JAK-STAT cascade 71 GO:0048672 BP 1.53e-03 4.05e-02 positive regulation of collateral sprouting 72 GO:0048705 BP 1.41e-03 4.05e-02 skeletal system morphogenesis 73 GO:0015884 BP 1.53e-03 4.29e-02 folic acid transport 74 GO:0002040 BP 2.19e-03 4.99e-02 sprouting angiogenesis 75 GO:0019221 BP 2.30e-03 4.99e-02 cytokine-mediated signaling pathway 76 GO:0030168 BP 2.20e-03 4.99e-02 platelet activation 77 GO:0033622 BP 2.27e-03 4.99e-02 integrin activation 78 GO:0060068 BP 2.27e-03 4.99e-02 vagina development 79 GO:0060346 BP 2.27e-03 4.99e-02 bone trabecula formation 80 GO:0061077 BP 2.03e-03 4.99e-02 chaperone-mediated protein folding 81 GO:2000774 BP 2.27e-03 4.99e-02 positive regulation of cellular senescence --------------------------------------------------------------------------------------------------------------------------------- GOID Ontology Pvalue FDR Term 1 GO:0005179 MF 8.19e-17 2.06e-14 hormone activity 2 GO:0005201 MF 5.32e-07 1.18e-04 extracellular matrix structural constituent 3 GO:0048407 MF 8.21e-07 1.18e-04 platelet-derived growth factor binding 4 GO:0005178 MF 3.96e-06 3.80e-04 integrin binding 5 GO:0005528 MF 7.44e-06 5.35e-04 FK506 binding 6 GO:0004930 MF 6.71e-06 5.72e-04 G-protein coupled receptor activity 7 GO:0005344 MF 4.78e-06 5.72e-04 oxygen transporter activity 8 GO:0002020 MF 2.80e-05 1.62e-03 protease binding 9 GO:0004222 MF 4.66e-05 2.24e-03 metalloendopeptidase activity 10 GO:0005518 MF 7.04e-05 2.90e-03 collagen binding 11 GO:0004984 MF 5.86e-05 3.75e-03 olfactory receptor activity 12 GO:0008237 MF 1.19e-04 4.28e-03 metallopeptidase activity 13 GO:0019825 MF 9.36e-05 4.72e-03 oxygen binding 14 GO:0001968 MF 1.48e-04 4.73e-03 fibronectin binding 15 GO:0020037 MF 1.15e-04 4.83e-03 heme binding 16 GO:0005044 MF 2.69e-04 7.73e-03 scavenger receptor activity 17 GO:0034711 MF 4.66e-04 1.22e-02 inhibin binding 18 GO:0005509 MF 6.15e-04 1.36e-02 calcium ion binding 19 GO:0016853 MF 5.91e-04 1.36e-02 isomerase activity 20 GO:0004871 MF 4.34e-04 1.59e-02 signal transducer activity 21 GO:0003755 MF 8.33e-04 1.71e-02 peptidyl-prolyl cis-trans isomerase activity 22 GO:0005125 MF 8.51e-04 3.06e-02 cytokine activity 23 GO:0005149 MF 6.40e-04 3.82e-02 interleukin-1 receptor binding 24 GO:0005506 MF 1.40e-03 3.85e-02 iron ion binding 25 GO:0008504 MF 1.53e-03 3.85e-02 monoamine transmembrane transporter activity 26 GO:0048018 MF 1.38e-03 3.85e-02 receptor agonist activity 27 GO:0008517 MF 9.24e-04 4.02e-02 folic acid transporter activity 28 GO:0016176 MF 2.27e-03 4.36e-02 superoxide-generating NADPH oxidase activator activity 29 GO:0043236 MF 2.52e-03 4.42e-02 laminin binding 30 GO:0046332 MF 2.61e-03 4.42e-02 SMAD binding 31 GO:0005539 MF 2.87e-03 4.59e-02 glycosaminoglycan binding 32 GO:0008083 MF 3.11e-03 4.68e-02 growth factor activity 33 GO:0050840 MF 3.25e-03 4.68e-02 extracellular matrix binding ########################################################################################################### # # ENSG00000249859 PVT1 # ########################################################################################################### GOID Ontology Pvalue FDR Term 1 GO:0006351 BP 6.78e-11 2.49e-08 transcription, DNA-templated 2 GO:0006355 BP 6.08e-11 2.49e-08 regulation of transcription, DNA-templated 3 GO:0050896 BP 8.34e-07 6.89e-04 response to stimulus 4 GO:0071371 BP 1.91e-05 7.90e-03 cellular response to gonadotropin stimulus 5 GO:0000122 BP 5.39e-05 1.53e-02 negative regulation of transcription from RNA polymerase II promoter 6 GO:0051923 BP 3.79e-05 2.09e-02 sulfation 7 GO:0097267 BP 3.79e-05 2.09e-02 omega-hydroxylase P450 pathway 8 GO:0009952 BP 9.64e-05 2.65e-02 anterior/posterior pattern specification 9 GO:0006068 BP 1.04e-04 2.88e-02 ethanol catabolic process 10 GO:0019216 BP 8.28e-05 2.88e-02 regulation of lipid metabolic process 11 GO:0021513 BP 4.66e-04 4.81e-02 spinal cord dorsal/ventral patterning 12 GO:0021517 BP 4.66e-04 4.81e-02 ventral spinal cord development 13 GO:0021631 BP 4.66e-04 4.81e-02 optic nerve morphogenesis 14 GO:0021696 BP 4.66e-04 4.81e-02 cerebellar cortex morphogenesis 15 GO:0045893 BP 3.42e-04 4.81e-02 positive regulation of transcription, DNA-templated 16 GO:0048856 BP 5.08e-04 4.81e-02 anatomical structure development 17 GO:0043401 BP 5.71e-04 4.87e-02 steroid hormone mediated signaling pathway -------------------------------------------------------------------------------------------------------------------------------------------- GOID Ontology Pvalue FDR Term 1 GO:0003676 MF 6.14e-20 1.53e-17 nucleic acid binding 2 GO:0003677 MF 6.46e-16 8.05e-14 DNA binding 3 GO:0046872 MF 4.84e-09 4.01e-07 metal ion binding 4 GO:0003700 MF 3.68e-07 2.29e-05 transcription factor activity, sequence-specific DNA binding 5 GO:0043565 MF 2.23e-04 1.19e-02 sequence-specific DNA binding 6 GO:0003707 MF 3.99e-04 1.77e-02 steroid hormone receptor activity 7 GO:0017150 MF 4.66e-04 2.32e-02 tRNA dihydrouridine synthase activity 8 GO:0000981 MF 4.62e-04 2.36e-02 RNA polymerase II transcription factor activity, sequence-specific DNA binding 9 GO:0004930 MF 6.01e-04 2.36e-02 G-protein coupled receptor activity 10 GO:0008527 MF 3.94e-04 2.36e-02 taste receptor activity 11 GO:0030284 MF 4.66e-04 2.36e-02 estrogen receptor activity 12 GO:0004879 MF 1.04e-03 2.65e-02 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding 13 GO:0033038 MF 9.67e-04 2.65e-02 bitter taste receptor activity 14 GO:0004984 MF 1.25e-03 2.89e-02 olfactory receptor activity 15 GO:0003723 MF 1.07e-03 4.43e-02 RNA binding 16 GO:0004062 MF 1.55e-04 4.80e-02 aryl sulfotransferase activity