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{"sheet":"Suppl Table 4","index":0,"n_rows":132,"n_cols":27,"rows_kept":132,"flags":["formulas_cached_only"]}
[null,null,"L01","N06","N05","J05","N02","M01","L04","S01","N03","G02","J01","C01","C09","B01","M02","G03","D11","N01","V08","N07","A10","C02","C07","H03","R03"]
[null,null,"L","N","N","J","N","M","L","S","N","G","J","C","C","B","M","G","D","N","V","N","A","C","C","H","R"]
["Anaemia","Blood",3,0,0,4,0,0,2,3,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Bone marrow failure","Blood",11,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Neutropenia","Blood",5,0,1,3,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Thrombocytopenia","Blood",4,0,0,3,0,0,1,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Aplastic anaemia","Blood",2,0,0,1,0,0,2,1,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Pancytopenia","Blood",0,0,0,2,0,0,0,2,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Leukopenia","Blood",2,0,0,1,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Myocardial infarction","Card",2,2,0,0,0,15,2,7,0,6,0,5,0,1,9,3,4,0,0,0,0,0,4,0,0]
["Cardiac failure","Card",5,0,9,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,3,0,0,0,0]
["Arrhythmia","Card",1,0,0,0,1,0,0,0,0,0,0,5,0,0,0,0,0,0,0,1,0,0,1,0,0]
["Cardiac failure congestive","Card",4,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3,0,0,0,0]
["Torsade de pointes","Card",2,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0]
["Cardiac arrest","Card",0,0,1,0,0,0,0,0,0,0,0,3,0,0,0,0,0,0,1,0,0,0,0,0,0]
["Tachycardia","Card",1,0,1,0,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,1,0,0]
["Coronary artery disease","Card",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,4,0,0]
["Congenital anomaly","Cong",4,0,0,2,0,1,7,2,3,1,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0]
["Congenital aortic valve stenosis","Cong",2,0,0,0,0,0,4,0,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Teratogenicity","Cong",3,0,0,1,0,0,2,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Deafness","Ear",1,2,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Blindness","Eye",1,0,0,0,0,0,0,0,2,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Gastrointestinal haemorrhage","Gastr",2,0,0,0,0,15,0,7,0,3,0,2,0,0,9,0,4,0,0,0,0,0,0,0,0]
["Peptic ulcer","Gastr",1,0,0,0,0,15,0,7,0,3,0,2,0,0,9,0,4,0,0,0,0,0,0,0,0]
["Diarrhoea","Gastr",5,0,0,0,0,1,2,0,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Nausea","Gastr",3,0,0,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0]
["Colitis","Gastr",1,0,0,0,0,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Vomiting","Gastr",3,0,0,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0]
["Stomatitis","Gastr",4,0,0,0,0,1,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Ascites","Gastr",4,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Pancreatitis","Gastr",0,0,0,2,0,0,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Abdominal pain","Gastr",0,0,0,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0]
["Intestinal perforation","Gastr",3,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Death","Genrl",16,3,24,5,13,0,7,2,6,0,1,3,10,0,0,1,0,6,1,3,1,0,0,0,5]
["Perforation","Genrl",5,0,0,0,0,15,2,7,0,3,0,2,0,0,9,0,4,0,0,0,0,0,0,0,0]
["Ulcer","Genrl",1,0,0,0,0,15,0,7,0,3,0,2,0,0,9,0,4,0,0,0,0,0,0,0,0]
["Pain","Genrl",1,2,1,0,3,0,2,1,3,0,0,0,0,0,0,1,0,1,0,1,1,2,0,0,0]
["Sudden death","Genrl",1,3,9,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Drug interaction","Genrl",1,0,0,0,6,0,0,0,0,1,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0]
["Fibrosis","Genrl",2,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,4,0,0,0,0,0,0]
["Asthenia","Genrl",1,0,1,0,0,0,0,1,3,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Oedema","Genrl",3,0,0,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0,1,0,2,0,0,0,0]
["Pyrexia","Genrl",2,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0]
["Necrosis","Genrl",5,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Discomfort","Genrl",0,2,0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Chest pain","Genrl",0,2,1,0,0,0,2,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0]
["Hyperplasia","Genrl",0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0]
["Malaise","Genrl",0,0,0,0,0,0,0,0,4,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0]
["Drug tolerance","Genrl",2,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Hepatotoxicity","Hepat",10,0,0,5,1,0,4,0,3,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0]
["Hepatic failure","Hepat",1,0,0,5,1,0,2,0,4,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0]
["Hepatitis","Hepat",0,0,0,11,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Liver disorder","Hepat",3,0,0,0,0,0,4,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0]
["Liver injury","Hepat",0,0,0,0,1,0,2,0,4,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0]
["Hepatomegaly","Hepat",0,0,0,9,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Acute hepatic failure","Hepat",0,0,0,0,1,0,0,0,4,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0]
["Chronic hepatitis","Hepat",0,0,0,5,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Jaundice","Hepat",0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0]
["Immunosuppression","Immun",1,0,0,2,0,0,6,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0]
["Hypersensitivity","Immun",5,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0]
["Immunodeficiency","Immun",0,0,0,6,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Anaphylactic reaction","Immun",5,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0]
["Infection","Infec",10,0,1,9,0,0,5,2,1,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0]
["Hepatitis A","Infec",0,0,0,11,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Hepatitis D","Infec",0,0,0,11,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Pneumonia","Infec",2,0,9,0,0,0,2,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Hepatitis B","Infec",0,0,0,9,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["HIV infection","Infec",0,0,0,6,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Chronic hepatitis B","Infec",0,0,0,5,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Pneumocystis jirovecii pneumonia","Infec",2,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Lactic acidosis","Metab",0,0,0,9,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0]
["Acidosis","Metab",0,0,0,9,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0]
["Decreased appetite","Metab",0,0,0,0,0,0,0,0,4,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3,0]
["Diabetes mellitus","Metab",0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,4,0,1,0,0,0,0]
["Obesity","Metab",0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,4,0]
["Rheumatoid arthritis","Musc",3,0,0,0,0,1,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Arthritis","Musc",2,0,0,0,0,1,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Muscular weakness","Musc",0,0,0,0,0,0,0,1,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Neoplasm malignant","Neopl",14,0,0,1,0,0,1,1,0,3,0,0,0,0,0,4,0,0,0,0,2,0,0,0,0]
["Lymphoma","Neopl",3,0,0,0,0,0,10,1,0,0,0,0,0,0,0,0,3,0,0,0,0,0,0,0,0]
["Breast cancer","Neopl",1,0,0,0,0,0,0,0,0,3,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0]
["Endometrial cancer","Neopl",0,0,0,0,0,0,0,0,0,3,0,0,0,0,0,4,0,0,0,0,0,0,0,0,0]
["Leukaemia","Neopl",5,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Cerebrovascular accident","Nerv",2,2,0,0,0,15,2,7,0,6,0,3,0,2,9,5,4,0,0,0,0,0,0,0,0]
["Coma","Nerv",1,0,7,0,10,0,0,0,1,0,0,0,0,0,0,0,0,3,2,3,0,0,0,0,0]
["Sedation","Nerv",0,0,7,0,11,0,0,0,1,0,0,0,0,0,0,0,0,2,0,3,0,0,0,0,0]
["Dementia","Nerv",0,0,18,0,0,0,0,0,0,3,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0]
["Seizure","Nerv",1,0,1,1,0,0,0,1,4,0,1,0,0,0,0,0,0,1,2,1,0,0,0,0,0]
["Paralysis","Nerv",1,0,0,0,0,0,0,0,0,0,0,0,0,5,0,0,0,0,1,0,0,0,0,0,0]
["Lethargy","Nerv",0,0,1,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0]
["Nervous system disorder","Nerv",0,0,0,0,1,0,0,0,0,0,0,0,0,5,0,0,0,0,0,0,0,0,0,0,0]
["Syncope","Nerv",0,2,1,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0]
["Epilepsy","Nerv",0,0,0,0,0,0,0,0,5,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Neurotoxicity","Nerv",3,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Neuropathy peripheral","Nerv",1,0,0,0,0,0,0,1,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Anaesthesia","Nerv",0,0,0,0,0,0,0,0,0,0,0,0,0,5,0,0,0,0,0,0,0,0,0,0,0]
["Myasthenia gravis","Nerv",0,0,0,0,0,0,0,1,0,0,3,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Pregnancy","Preg",7,0,0,3,11,1,9,1,3,2,2,0,10,0,0,1,0,1,0,2,0,4,0,1,0]
["Foetal death","Preg",5,0,0,0,0,0,7,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Delivery","Preg",0,0,0,0,1,1,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0]
["Depression","Psych",0,24,7,0,13,0,0,0,3,0,0,0,0,0,0,0,0,3,0,6,0,0,0,0,0]
["Substance abuse","Psych",0,7,3,0,13,0,0,0,0,0,0,0,0,0,0,0,0,6,0,4,0,0,0,0,0]
["Dependence","Psych",0,7,2,0,13,0,0,0,0,0,0,0,0,0,0,0,0,5,0,3,0,0,0,0,0]
["Nervousness","Psych",2,0,0,0,10,0,0,1,0,0,2,0,0,0,0,0,0,3,0,3,0,0,0,0,0]
["Psychotic disorder","Psych",0,4,18,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Completed suicide","Psych",0,21,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,0]
["Withdrawal syndrome","Psych",0,0,0,0,11,0,0,0,0,0,0,0,0,0,0,0,0,1,0,2,0,0,0,0,0]
["Social avoidant behaviour","Psych",0,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0]
["Renal impairment","Renal",1,0,0,2,0,0,1,1,0,0,2,0,0,0,0,0,0,0,0,0,1,0,0,0,0]
["Nephropathy toxic","Renal",3,0,0,2,0,0,1,1,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Acute kidney injury","Renal",0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,5,0,0,0,0,0,0]
["Renal failure","Renal",1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0]
["Endometrial hyperplasia","Repro",0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0]
["Genital haemorrhage","Repro",0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0]
["Respiratory depression","Resp",0,0,6,0,13,0,0,0,1,0,0,0,0,0,0,0,0,3,0,4,0,0,0,0,0]
["Dyspnoea","Resp",4,2,1,0,0,0,2,0,0,0,0,0,0,0,0,1,0,0,0,0,4,0,0,0,0]
["Pulmonary embolism","Resp",0,0,0,0,0,0,3,0,1,2,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0]
["Cough","Resp",2,0,0,0,0,0,2,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0]
["Asthma","Resp",0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,5]
["Bronchospasm","Resp",4,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Rash","Skin",3,0,0,2,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Toxic epidermal necrolysis","Skin",0,0,1,1,0,0,0,0,2,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Psoriasis","Skin",2,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
["Haemorrhage","Vasc",7,0,0,1,0,15,0,7,1,6,0,2,0,6,9,4,4,0,1,0,0,0,0,0,0]
["Infarction","Vasc",2,0,0,0,0,15,2,7,0,6,0,5,0,0,9,3,4,0,0,0,0,0,4,0,0]
["Hypotension","Vasc",5,0,1,0,2,0,0,1,1,1,0,1,0,1,0,0,0,0,0,0,1,1,0,0,0]
["Thrombosis","Vasc",1,0,0,0,0,0,5,1,0,3,0,0,0,0,0,5,0,0,0,0,0,0,0,0,0]
["Deep vein thrombosis","Vasc",0,0,0,0,0,0,3,0,0,3,0,0,0,0,0,5,0,0,0,0,0,0,0,0,0]
["Embolism","Vasc",1,0,0,0,0,0,3,0,0,2,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0]
["Hypertension","Vasc",0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,4,0,0,0,4,0,0]
["Haematoma","Vasc",0,0,0,0,0,0,0,0,0,0,0,0,0,5,0,0,0,0,0,0,0,0,0,0,0]
[null,"Total",50,33,27,21,18,17,15,15,11,11,11,10,10,10,9,9,7,7,7,6,6,5,5,5,5]