Trait n_tot n_informative recent_pmid recent_year recent_size recent_nsignif size_tau size_se size_pval nsignif_tau nsignif_se nsignif_pval taudiff_z taudiff_p taudiff_str informative_nsignif robust_estimate_doubling Age-related macular degeneration 11 5 23455636 2013.1698630136987 9495.60043274432 19 1.237216055275475 0.09655983129190025 0.0010258440741677797 1.849674918468538 0.12476932443415097 0.0006659466051531858 -3.8819875179174654 0.00010360619660809743 saturating 47 True Alzheimer's disease 19 10 30636644 2019.0328767123287 9244.759496567505 54 3.1475389247378285 1.1491775712515084 0.025490610934332705 2.194374058580639 0.26634645959967757 3.531434710745155e-05 0.8080136394123106 0.4190827304057575 tie 83 False Alzheimer's disease (late onset) 12 6 30617256 2019.0191780821917 67025.4366542422 22 1.6970465541933903 0.3993632295043877 0.013164571477939611 2.4060891259697406 0.5038271474910747 0.008803704881638858 -1.1028650780258666 0.2700857616658985 tie 53 False Amyotrophic lateral sclerosis 12 5 29566793 2018.2191780821918 61743.30847289419 6 2.192062190578873 0.33163422643647794 0.007050413638946778 4.655084080971478 1.2067253351463405 0.030782153508772954 -1.9681092223078491 0.04905547196485876 saturating 18 False Asthma 21 9 32296059 2020.2876712328766 295550.4496098593 312 1.673931694099034 0.24885664217565 0.0002707746539220383 1.649125314283482 0.17058602839267892 2.672658504322121e-05 0.08221914852592214 0.9344724466751996 tie 542 True Asthma (childhood onset) 7 6 31669095 2019.813698630137 51964.39839555754 219 1.0625591828304637 0.1458531783411363 0.0018868068471629123 1.287712825225922 0.35235481565132304 0.02168345187998868 -0.5904136048454905 0.5549133917382219 tie 331 True Atrial fibrillation 10 6 29892015 2018.4438356164383 232656.1405260205 213 2.396630180774182 0.8145762830164418 0.04229719919620219 1.4699599094826648 0.16108436907677315 0.000800110807732556 1.1159983316550537 0.26442284873905086 tie 265 False Basal cell carcinoma 9 6 31174203 2019.4328767123288 120940.93870730934 71 1.755701623652959 0.466533245138967 0.019718560654782665 1.949452848387202 0.16015791473186997 0.0002614571756770711 -0.39279865030661737 0.6944682016133095 tie 131 True Bipolar disorder 13 10 31043756 2019.331506849315 49367.473680139236 32 2.854622251594595 0.6431295820757584 0.00217186685907104 2.6479448489452504 0.3076524791775575 2.5701528619310258e-05 0.2898995829940254 0.7718930606565455 tie 64 False Birth weight 7 4 31043758 2019.331506849315 321223 213 1.802118375406209 0.06949265460354223 0.0014836921452481514 1.3337059250378833 0.025342584309761464 0.00036086644885986133 6.332514541257745 2.4119754693897735e-10 discovering 280 True Body mass index 38 8 31669095 2019.813698630137 457822 1636 2.612356944924729 0.5336287029845607 0.0027233452440416092 1.286340479457561 0.12610514166838627 5.1713879981202135e-05 2.4182966486845836 0.015593358583270246 discovering 3320 False Breast cancer 28 5 29059683 2017.8109589041096 138039.9426741531 379 1.4922355727240155 0.1892130544538266 0.0042484367646782135 1.5706127726079029 0.1654046288380927 0.0024764685394996076 -0.3118657993515801 0.7551425152579132 tie 574 True Calcium levels 5 4 29403010 2018.0986301369862 71701 17 3.449662936823132 0.7838621541087801 0.047949592632624646 1.7854808037128462 0.4091697411658336 0.048711307292093525 1.8820728329816003 0.05982612738889862 tie 27 False Celiac disease 9 4 22057235 2011.849315068493 24267.559108327496 35 1.1036311546730289 0.16924135113800456 0.022717805490230582 1.0563328677135524 0.2297765228166085 0.04420257388140201 0.1657398093598419 0.8683617159596668 tie 69 True Chronic obstructive pulmonary disease 9 6 30804561 2019.1534246575343 123127.18790121446 102 1.7590843083082048 0.22954525661895844 0.0015585388675798959 1.6351491740133368 0.29132695259642205 0.004951151489648265 0.3341523663311653 0.7382645861771135 tie 133 True Chronotype 5 4 30696823 2019.0794520547945 449734 425 1.4458805378161852 0.15873808052181226 0.01183943565255349 0.44701976792899306 0.0849550545295167 0.03427213167277499 5.547930464313233 2.890707910984086e-08 discovering 449 True Colorectal cancer 30 14 31089142 2019.3671232876711 82912.80518893801 78 2.3702224606601914 0.22046936465083916 1.629250492324772e-07 2.325416513718738 0.21619534948898994 1.620500717144159e-07 0.14510479262719403 0.8846281343711667 tie 192 True Depression 4 4 30718901 2019.0958904109589 684816.7338614308 97 0.7002458818978508 0.10654528183449335 0.022376739427781976 0.6254063366953759 0.0749314414286509 0.014053128449935844 0.5745575008630006 0.5655906016141989 tie 228 True Educational attainment (years of education) 4 3 30038396 2018.558904109589 1131881 1640 1.6373260057080832 0.0935388156010457 0.036329968737431335 0.5629199829324962 0.03342604614847628 0.03775798500212922 10.816332734128093 2.8807475824852145e-27 discovering 1805 True Eosinophil counts 6 3 30595370 2018.9890410958903 440000 703 1.7993568694196374 0.05729471891451223 0.020264257593742195 1.4002675738432386 0.0468326039304585 0.02128411227694396 5.393109616195134 6.924867812560135e-08 discovering 917 True Glaucoma 7 4 30054594 2018.5698630136985 40529.80534846739 34 1.484077938626918 0.15981245371812722 0.01139810993691254 1.6764367343667474 0.08202082774367293 0.0023851626414585223 -1.0708529000617013 0.28423557661720555 tie 44 True HDL cholesterol 28 5 30275531 2018.7506849315068 297626 158 2.390263777982826 0.6888510773722247 0.04034846037371985 2.735818349737275 0.5853619419933643 0.01849979770077393 -0.38226269860247863 0.7022665197382749 tie 299 False Height 28 6 30595370 2018.9890410958903 458000 2413 1.8426452211780948 0.6192008447981757 0.040906790966548236 1.134904292577179 0.3135381792740106 0.022363774102791046 1.0197150560304344 0.30786361902352144 tie 2643 False Hypothyroidism 5 4 30595370 2018.9890410958903 459000 140 1.2045388279042426 0.18394204914599357 0.022534322600073736 1.1796554052015773 0.23213641322576256 0.03661033291365398 0.08401481493625965 0.9330446527978756 tie 167 True Inflammatory bowel disease 7 4 26192919 2015.5506849315068 32372.289045365345 165 1.6860884451646883 0.3562760337502719 0.04186519833578974 1.161275718568665 0.20073143984955724 0.02860287027759733 1.2833727589989952 0.1993615129157742 tie 282 True Intraocular pressure 12 5 29617998 2018.2383561643835 115486 320 2.245788660097669 0.6544605034115915 0.041492215220116126 0.9991450069600323 0.2739097982964608 0.03554910974759263 1.7571522606740093 0.07889185990704554 tie 396 False LDL cholesterol 22 7 30275531 2018.7506849315068 297626 125 1.7070189007683094 0.46022910113565924 0.013868367860013364 2.0746576449376524 0.6029936666662092 0.018423521309607293 -0.4846539378669765 0.6279218458662501 tie 244 False Lung cancer 13 9 28604730 2017.4465753424658 77094.8574361846 56 1.8337830874164212 0.48443174233880465 0.006843576235429374 1.92647217996443 0.2998713015018149 0.0003588896909541375 -0.16268834433204077 0.870763824597244 tie 79 True Male-pattern baldness 9 6 30573740 2018.9698630136986 205327 622 1.3829785783347908 0.26273236861986937 0.006238232494635828 1.1226698817256475 0.18485331047681122 0.003713364879002952 0.8103093323654035 0.41776241301571193 tie 1008 True Mean corpuscular hemoglobin 12 4 30595370 2018.9890410958903 443000 774 2.0414935025505154 0.24814675224008884 0.01445520419561725 1.498757030568259 0.07280604519071848 0.00235146472481435 2.098692893789779 0.03584398150922785 discovering 1073 True Mean platelet volume 10 4 27863252 2016.8794520547945 164454 294 1.2521227217620141 0.16569822407170867 0.017065258025942977 1.3094444541074493 0.20500121433165844 0.023643946075484843 -0.21746282658910843 0.8278476738829299 tie 338 True Menarche (age at onset) 9 5 30595370 2018.9890410958903 242000 316 2.52036304599028 0.7887825852600795 0.04951126224643887 1.267297112776287 0.3583984085530168 0.03847358627238367 1.446311103876153 0.14808996271988856 tie 473 False Migraine 6 6 27322543 2016.468493150685 200788.16423598546 44 1.230782314039031 0.2849841410880562 0.012459442839923339 1.2950516533283283 0.17064473409840777 0.0016169832879296727 -0.19348443445016034 0.8465795952410787 tie 85 True Neuroblastoma 3 3 22941191 2012.6712328767123 5602.666666666667 6 4.16490815315438 0.22761269084729352 0.03475676650973152 1.6663887359371408 0.03650133178233445 0.013942577511543064 10.838580981642359 2.259484624323956e-27 discovering 10 False Neuroticism 10 5 29942085 2018.482191780822 449484 371 1.1517447953947915 0.15869699329275727 0.0053975118144813415 0.384408569220791 0.02936889459291302 0.0009631700170673207 4.754497414044708 1.989406879004734e-06 discovering 535 True Osteoarthritis 4 4 30664745 2019.0575342465754 256039.8381269757 34 1.4510021401963296 0.2342284430002531 0.025081894294830088 1.3701517567093098 0.10451489618023485 0.005768310484688107 0.31522036265965253 0.7525943459237696 tie 37 True Parkinson's disease 17 6 28892059 2017.695890410959 76832.90012167432 40 1.9241533460755587 0.377479754187972 0.0069954193113581226 2.420229317859513 0.4322025901563985 0.004992928861965537 -0.8644878461660775 0.38731995405955566 tie 104 True Prostate cancer 30 9 29892016 2018.4438356164383 137933.11243886093 135 1.9872024585572607 0.2914114843195788 0.0002488244467953327 2.2479018623820006 0.2894685455285008 0.00011015272438338718 -0.6346965832466183 0.5256263224987442 tie 271 True Red blood cell count 9 3 30595370 2018.9890410958903 445000 851 1.8168912726635948 0.07387394249868866 0.02587040976665132 1.345650729054319 0.08759725788739048 0.04138337977839747 4.112441357683333 3.914969349915461e-05 discovering 1071 True Refractive error 5 4 32231278 2020.2438356164384 542934 448 1.4261911486795242 0.2470253817546281 0.028714544639949272 1.1104933431144934 0.22681473752211012 0.03927550429043957 0.9413693236731089 0.3465156283148547 tie 474 True Rheumatoid arthritis 24 7 24390342 2013.9835616438356 58392.070577325525 147 1.6807678906750938 0.20958278116219342 0.0004872858591818229 1.251341533253026 0.13688352206887983 0.00026245362092974507 1.7154830436277084 0.08625670158321554 tie 209 True Sarcoidosis 3 3 26051272 2015.7068493150684 5250.794672586016 6 1.8722374284867056 0.03426608496652027 0.011650248858051009 1.1969269668835456 0.03214879981642538 0.017095146642730187 14.372505193403859 7.699492878365484e-47 discovering 8 False Systemic lupus erythematosus 22 6 28714469 2017.5424657534247 26873.80285776456 126 2.9984725911082144 0.6077174059709943 0.007850407323319469 2.137531805393685 0.27862813570251294 0.001552174070778473 1.2877804495934857 0.1978223996478633 tie 251 False Systolic blood pressure 22 6 30595370 2018.9890410958903 422000 673 2.517722843848493 0.17762517829081612 0.00014383436103727326 1.4665763663408804 0.21241253730426174 0.00230798609904934 3.7962176366904736 0.0001469205288760399 discovering 1343 True Triglycerides 23 6 29507422 2018.1753424657534 283251 537 1.8482113444753177 0.5295650280178232 0.025121581684069156 1.7687486505941223 0.2024458102280594 0.0009456126642476125 0.14016013974691446 0.8885334648354664 tie 634 False Type 2 diabetes 61 10 30297969 2018.7698630136986 272025.74568937684 287 1.814020830466384 0.17851288482916344 7.528383388493077e-06 1.9568289952916387 0.28300121592829947 0.00012271388141067482 -0.4268038295160651 0.6695222169816799 tie 677 True Urate levels 11 9 31578528 2019.7534246575342 457690 466 1.429274364308548 0.2621265453626493 0.0009533401397865449 1.3010218559563786 0.09688592057542922 2.979406610070808e-06 0.4589317618326712 0.6462831693882842 tie 518 True Venous thromboembolism 9 5 31420334 2019.6246575342466 102866.95819249244 94 1.5218857533970975 0.179329450347566 0.0034354708113229714 1.6785074251631353 0.1499420500870063 0.0015280360531435373 -0.6700232492811516 0.5028429694873613 tie 113 True White blood cell count 13 5 30595370 2018.9890410958903 444000 715 1.7794010107458038 0.13349419330499926 0.0009126537485379707 1.2618609194507626 0.2174367811207945 0.010182549131092738 2.028408057114231 0.042518618463811185 discovering 925 True