>74-c -MGIII-----------LL--------------------------LRIKQQLIWMWRHLY ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYTYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAN------KYLGPSC SLS---------WLVQLFLNILAATRVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYP-- --MLW-----------VVS------------------IFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISS------MKSR------- ----S-SILLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.7-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYP-- --MPW-----------VVS------------------IFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISS------MKSR------- ----S-SILLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.1-s -MDIII-----------LL--------------------------LRIKQQLIWMWKHLY ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYP-- --MLW-----------VVS------------------IFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISS------MKSR------- ----S-SILLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.1-x -MDIII-----------LL--------------------------LRIKQQLIWMWKHLY ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFF------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYP-- --MLW-----------VVS------------------IFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISS------MKSR------- ----S-SILLPCF-------------------------GKR------------------- -------------------------------ELSQRIR---------------------- ------------------------------------------------------------ ------------- >74-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAFE---------NIVL---GI---------FLFF------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLCCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLC---------WLVQLFLNILAAARVSGPHYNKNTIN-RMHLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYLYSSILIIFTTY------------SKYP-- --MLW-----------VVS------------------IFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISS------MKSR------- ----S-SILLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.2-x -MDIII-----------LL--------------------------LRIKQQLIWMWKHLY ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFF------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRAMKTILILVCTFVL---SYSFSSIVAVFTTY------------SKYP-- --LLW-----------RIS------------------VFTLIEI---------------- ---C--FP-----------------------I-C--C---P--------------FV--- --------L-------------------------------ISN------MKSR------- ----S-SVFLPCF-------------------------CKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.1-p ---------------------------------------------------------MLY ------------------------------------------------------------ -------------------------------------------------------GIW-- ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSSILAYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANYLFIISKGIPQTL------------SDYGYKNFLDDFGCKLIMYIYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGSSC SLS---------WLVQLFLNILTAARVSGPHYNKNTTN-GMIHGYCSWF-ASGNFATVLY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATKTILILVCTFVL---SYSFSSILVIFTTY------------SKYP-- --MLW-----------VVS------------------VFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISS------MKSR------- ----F-SILLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.2-p ---------------------------------------------------------MLY ------------------------------------------------------------ -------------------------------------------------------GIW-- ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSSILAYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANYLFIISKGIPQTL------------SDYGYKNFLDDFGCKLIMYIYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGSSC SLS---------WLVQLFLNILTAARVSG-----------------------------LP VAYACLKD---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74-z -MG--------------------------------------------------------- ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFF------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-CSSVSMVSMLYRHKKQ----VKHIHSAQDF-- ---LKVSPEIRAMKTILILVCTFIL---SYSFSSMVAIVTAY------------SKYP-- --ELW-----------GVS------------------VFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------MKPI------- ----S-NLFLPCF-------------------------HNN------------------- -------------------------------FLKE------------------------- ------------------------------------------------------------ ------------- >80.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAFE---------NIAL---GI---------FLFS------------- ---QITVGMI------------GNSSILFYYVILKFTG---K-----HLMPKDL-IIEHL -------TVANCLFIISKGIPQTL------------SDYGLKDFLDDFGCKLIMYIYRI- ---TRGMSLYAMCLLSCF-------QAITISPSNS-RWM-KFKHRAT------KYLGPSC SLS---------WLVHSFLNILTPARVSGPSYSKNTTN-RMIYGYCSWF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSM-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------L-W--I---P--------------NA--- --------S-------------------------------VNK------V---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >80.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAFE---------NIAL---GI---------FLFS------------- ---QITVGMI------------GNSSILFYYVILKFTG---K-----HLMPKDL-IIEHL -------TVANCLFIISKGIPQTL------------SDYGLKDFLDDFGCKLIMYIYRI- ---TRGMSLYAMCLLSCF-------QAITISPSNS-RWM-KFKHRAT------KYLGPSC SLS---------WLVHSFLNILTPARVSGPSYSKNTTN-RMIYGYCSWF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSMLYRHKKQ----VKHIHRAQDF-- ---LKVSPEIRAMKTILILVCTFIL---SYSFSSMVAIVTAY------------SKYP-- --ELW-----------GVS------------------VFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------MKPI------- ----S-NLFLPCF-------------------------HNN------------------- -------------------------------FLKE------------------------- ------------------------------------------------------------ ------------- >80-z ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MAFE---------NIAL---GI---------FLFS------------- ---QITVGMI------------GNSSILFYYVILKFTG---K-----HLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SDYGLKDFLDDFGCKLIMYIYRI- ---TRGMSLYAMCLLSCF-------QAITISPSNS-RWM-KFKHRAT------KYLGPSC SLS---------WLVHSFLNILTPARVSGPSYSKNTTN-RMIYGYCSWF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-CSSVSMVSMLYRHKKQ----VKHIHSAQDF-- ---LKVSPEIRAMKTILILVCTFIL---SYSFSSMVAIVTAY------------SKYP-- --ELW-----------GVS------------------VFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------MKPI------- ----S-NLFLPCF-------------------------HNN------------------- -------------------------------FLKE------------------------- ------------------------------------------------------------ ------------- >74/80.1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MASE---------NIAL---GI---------FLFS------------- ---QITVGMI------------GNSLILFYYVILKFTG---K-----HLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SDYGLKDFLDDFGCKLIMYIYRI- ---TRGVSLYAMCLLSCF-------QAITISPSNS-RWM-MFKHRAT------KYLGPSC SFS---------WLVHSFLNILTPARVSGPSYNKNTTN-RMIYGYCSWF-ASGNFATALY VFLLCFSDGLCL-----------GLMA-GSSVSMVSMLYRHKKQ----VKHIHSAQDF-- ---LKVSPEIRAMKTILILVCTFIL---SYSFSSMVAIVTAY------------SKYP-- --ELW-----------G------------------------------------------- -------------------------------L-W--I---P--------------NA--- --------S-------------------------------VNK------V---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74/80.2-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MASE---------NIAL---GI---------FLFS------------- ---QITVGMI------------GNSLILFYYVILKFTG---K-----HLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SDYGLKDFLDDFGCKLIMYIYRI- ---TRGVSLYAMCLLSCF-------QAITISPSNS-RWM-MFKHRAT------KYLGPSC SFS---------WLVHSFLNILTPARVSGPSYNKNTTN-RMIYGYCSWF-ASGNFATALY VFLLCFSDGLCL-----------GLMA-GSSVSMVSMLYRHKKQ----VKHIHSAQDF-- ---LKVSPEIRAMKTILILVCTFIL---SYSFSSMVAIVTAY------------SKYP-- --ELW-----------GVS------------------VFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------MKPI------- ----S-NLFLHCF-------------------------HN-------------------- -------------------------------FLKE------------------------- ------------------------------------------------------------ ------------- >76-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----MTVGIF------------GNSSILFYYVILKLTG---K-----HLMPKDL-IIEHL -------TFANCLCIISKGIPQTL------------SDYGLKDFLDDFGCKLIMYIYRI- ---TRGVSFYAMCLLSCF-------QAITISPSNS-RWM-MLKYRGT------KYFGSSC SIS---------WLVHLFLNILIPARVSGPSYNKNITK-RMIYGSCSWF-SLSSFATALY LFLLCFSDGLCL-----------GLMA-GSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSFSSIVAIFTTY------------SKYP-- --LLW-----------RIS------------------VFTLIEI---------------- ---C--FP-----------------------I-C--C---P--------------FV--- --------L-------------------------------ISN------VKSR------- ----S-SVFLPCF-------------------------CKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >76.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----MTVGMF------------GNSLILFYYVILKLTG---K-----HLMPKDL-IIEHL -------TFANCLCIISKGIPQTL------------SDYGLKDFLDDFGCKLILYVYRI- ---TRGVSFYAMCLLSCF-------QAITISPSNS-RWM-MFKYRAT------KYFGSSC SIS---------WLVHLFLNILTPARVSGPSYNKNITK-RMIYGSCSWF-SLSNFATALY LFLLCFSDGLCL-----------GLMA-GSSVSMVSILYRHKKR----VKHIHSAQHF-- ---LKVSPEERATQTILILVCTFVL---SYSFSSIVAIFTTY------------SKYP-- --LLW-----------SIS------------------VFTLIEI---------------- ---C--FP-----------------------I-C--C---P--------------FV--- --------L-------------------------------ISN------MKSR------- ----A-SVFLPCF-------------------------CKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >76.2-m -MCF---------------------------------------------SGLIPIINLFY F----------------------------------------------------------- -----------------------------------------------------SIGIK-- ------------VAFE---------SIAL---GI---------FLFS------------- ---QMTVGMF------------GNSLILFYYVILKLTG---K-----HLMPKDL-IIEHL -------TFANCLCIISKGIPQTL------------SDYGLKDFLDDFGCKLILYVYRI- ---TRGVSFYAMCLLSCF-------QAITISPSNS-RWM-MFKYRAT------KYFGSSC SIS---------WLVHLFLNILTPARVSGPSYNKNITK-RMIYGSCSWF-SLSNFATALY LFLLCFSDGLCL-----------GLMA-GSSVSMVSILYRHKKR----VKHIHSAQHF-- ---LKVSPEERATQTILILVCTFVL---SYSFSSIVAIFTTY------------SKYP-- --LLW-----------SIS------------------VFTLIEI---------------- ---C--FP-----------------------I-C--C---P--------------FV--- --------L-------------------------------ISN------MKSR------- ----A-SVFLPCF-------------------------CKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >76-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----MTVGMF------------GNSLILFYYVILKLTG---K-----HLMPKDL-IIEHL -------TFANCLCIISKGIPQTL------------SDYGLKDFLDDFGCKLILYIYRI- ---TRGVSFYAMCLLSCF-------QAITISPSNS-RWM-MLKYRAT------KNVGPSC SIS---------WLVHLFLNILTPARVSGPSYNKNITK-RMIYGSCSWF-SLSNFGTALY LFLLCFSDGLCL-----------GLMA-GSSVSMVSILYRHKKR----VKHIHSAQHF-- ---LKVSPEDR------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >76-x -MC-----------------------------------------------------KQLY ------------------------------------------------------------ -------------------------------------------------------GIK-- ------------VAFE---------NIAL---GI---------FLFS------------- ---QMTVGMF------------GNSLILFYYVILKLTG---K-----HLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SDYGLKDFLDDFGCKLILYIYRI- ---TRGVSFYAMCLLSCF-------QAITISPSNS-RWM-MLKYRAT------KYFGPSC SIS---------WLVHLFLNTLTPARVSGPSYNKNITK-RMIYGSCSWF-SLSNFATALY LFLLCFSDGLCL-----------GLMA-GSSVSMVSMLYRHKKQ----VKHIHSAQDF-- ---LKVSPEIRAMKTILILVCTFIL---SYSFSSMVAIVTAY------------SKYP-- --ELW-----------G------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >76-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------MPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SDYGLKDFLDDFGCKLIMYIYRI- ---TRGVSFYAMCLLSCF-------QAITISPSNS-RWM-MLKYRAT------KYFGPSC SIS---------WLVHLFLNTLTPARVSGPSYNKNITK-RMIYGSCSWF-SLSNFATALY LFLLCFSDGLCL-----------GLMA-GSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYP-- --MLW-----------V------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.9-s -MDIII-----------LL--------------------------LRIKQQLIWMWKHLY ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSM-------------------------- ------------------------------------------------------------ --KVWLQE----KNTKIIH------------------CLAFLHD---------------- ------SQ-----------------------L-G-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.3-s -MDIII-----------LL--------------------------LRIKQQLIWMWKHLY ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYPML WVKVWLQE----KNTKIIH------------------CLAFLHD---------------- ------SQ-----------------------L-G-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.4-s -MDIII-----------LL--------------------------LRIKQQLIWMWKHLY ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYPML WVKMWLEE----RKRETIQ------------------RIFFLHD---------------- ------YQ-----------------------L-S--C---P--------------SE--- --------F-------------------------------KEI------LKDVLALGKAL ---SS-STFIIAM----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.11-s -MDIII-----------LL--------------------------LRIKQQLIWMWKHLY ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSM-------------------------- ------------------------------------------------------------ --KMWLEE----RKRETIQ------------------RIFFLHD---------------- ------YQ-----------------------L-S--C---P--------------SE--- --------F-------------------------------KEI------LKDVLALGKAL ---SS-STFIIAM----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.10-s ---------------------------------------------------MGPLWNRIF ------------------------------------------------------------ ------------------------------------------------------------ -------------------------DIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSM-------------------------- ------------------------------------------------------------ --KMWLEE----RKRETIQ------------------RIFFLHD---------------- ------YQ-----------------------L-S--C---P--------------SE--- --------F-------------------------------KEI------LKDVLALGKAL ---SS-STFIIAM----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.2-s -MDIII-----------LL--------------------------LRIKQQLIWMWKHLY ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYP-- --MLWV-----------VK------------------VLSLKKYPRMSGHGRGPKLDPYI SKAV--QP-----------------------T-S--C---T--------------LT--- --------I-------------------------------Y--------VKER------L ---SA-RKWTSCL-------------------------DLT------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.5-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVS----------------------------------------------------- ------------------K------------------VLSLKKYPRMSGHGRGPKLDPYI SKAV--QP-----------------------T-S--C---T--------------LT--- --------I-------------------------------Y--------VKER------L ---SA-RKWTSCL-------------------------DLT------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.6-s ---------------------------------------------------MIFS-RYPL ------------------------------------------------------------ -------------------------------------------------------GIR-- ------------MAFE---------NIVL---GI---------FLFS------------- ---QIAMGII------------GNSLILVYYVSLKLTG---K-----YLMPKDL-IIEHL -------TFANCLFIISKGIPQTL------------SNYGYKNFLDDFGCKLIIYAYRI- ---TRGMSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYP-- --MLWV-----------VK------------------VLSLKKYPRMSGHGRGPKLDPYI SKAV--QP-----------------------T-S--C---T--------------LT--- --------I-------------------------------Y--------VKER------L ---SA-RKWTSCL-------------------------DLT------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.12-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------M-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYP-- --MLWVKV----I---QVK------------------VLSLKKYPRMSGHGRGPKLDPYI SKAV--QP-----------------------T-S--C---T--------------LT--- --------I-------------------------------Y--------VKER------L ---SA-RKWTSCL-------------------------DLT------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >72-c ------------------------------------------------MEERKEGRKHRK KERRKEG--------------SI------------------------------QGR---- -------------------------------KEG-----------------KLNTGMK-- ------------MASE---------NVAM---GI---------FLFS------------- ---QMTVGML------------GNSSILFHYVILMFTG---K-----NLMPKDL-IIEHL -------TFANCLSIISRGIPQTL------------ADYGFKDFLDDTGCKLIVYIYRI- ---TRGVSLYAMCLLSCF-------QAITISPNNS-KGL-MLKQRVI------KYIGPSC SVS---------WLVHIFLNILTPARVSGPSYKKNVTN-MMSYAYCSWF-ASGNFATALY MFLLCFSDGLCL-----------GLMA-YSSVSMMIILYRHKRQ----VRHIHKAQYF-- ---LKQSPENRATQTILILVFTFII---SYSFSSIVVIFTTY------------SKYP-- --MLW-----------GVS------------------VFTFLEI---------------- ---C--FP-----------------------I-L--C---P--------------FV--- --------L-------------------------------LSN------MKPI------- ----S-SPFLPYF-------------------------VKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >72-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MASE---------NVAM---GI---------FLFS------------- ---QMTVGML------------GNSSILFYYVILMSTG---K-----NLMPKDL-IIEHL -------TFANCLSIISRGIPQTL------------ADYGFKDFLDVTGCKLIMYIYRI- ---TRGVSLYAMCLLSCF-------QAITISPNNS-KGL-MLKQRVI------KYIGPSC SVS---------WLVHIFLNILTPARVLGPSYKKNMTN-MMSYAYCSWF-SSGNFATALY MFLLCFSDGLCL-----------GLMA-CSSVSMIIILYRHKRQ----VRHIYKAQYF-- ---LKQSPENRATQTILILVFTFII---SYSFSSIVVIFTTY------------SKYP-- --MLW-----------GVS------------------VFTFVEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------LSN------MKPI------- ----S-RLFLPYF-------------------------VKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >72-z ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MASE---------NVAM---GI---------FLFS------------- ---QMTVGML------------GNSSILFYYVILMFTG---K-----NLMPKDL-IIEHL -------TFANCLSIISRGIPQTL------------ADYGFKDFLDDTGCKLIMYIYRI- ---TRGVSLYAMCLLSCF-------QAITISPNNS-KGL-MLKQRVI------KYIGPSC SVS---------WLVHIFLNILTPARVSGPSYKKNVTN-MMSYAYCSWF-ASGNFATALY MFLLCFSDGLCL-----------GLMA-CSSVSMIIILYRHKRQ----VRHIHKAQYF-- ---LKQSPENRATQTILILVFTFII---SYSFSSIVVIFTTY------------SKYP-- --MLW-----------GVS------------------VFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------LSN------MKPI------- ----S-SLFLPYF-------------------------VKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >72-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MASE---------NVAM---GI---------FLFS------------- ---QMTVGML------------GNSSILFYYVILMFTG---K-----NLMPKDL-IIEHL -------TFANCLSIISRGIPQTL------------ADYGFKDFLDYTGCKLIMYIYRI- ---KRGVSLYAMCLLSCF-------QAITISPNNS-KGL-MLKQRVI------KYIGPSC SVS---------WLVHIFLNILTPARVSGPSYKKNVTN-MMSYAYCSWF-ASGNFATALY MFLLCFSDRLCL-----------GLMA-CSSVSMIIIL---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >72-p ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MASE---------NVAM---GI---------FLFS------------- ---QITVGML------------GNSSILFYYVILMFTG---K-----NLMPKDL-IIEHL -------TFANCLSIISRGIPQTL------------ADYGFKYFLDDTGCKLIVYIYRI- ---TRGMSLYAMCLLSCF-------QAITISPNNS-KVL-MLKQRAI------KYIGPSC SVS---------WLVQVFLNILTPARVSGPSYKKNVTN-MMSYAYCSWF-ASGNFATALY MFLLCFSDGLCL-----------GLMA-CSSVSMTIILYRHKRQ----VRHIHKAQYF-- ---LKQSPENRATQTILILVCTFII---SYSFSSIVVIFTTY------------SKYP-- --MLW-----------GVS------------------VFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------LSN------MKPI------- ----S-RLFSPYF-------------------------FKK------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >242-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAFE---------NFAM---GI---------FLFS------------- ---QITVGML------------GNSSILFYYIILISTR---K-----PLMPKDL-IIEHL -------TFANCLSIISRGIPQTL------------SNYGFKDFLDDIGCKLINFIYRI- ---TRGMSLYAMCLLSCF-------QAITISPRNS-MWM-ILKHRAT------KYIGPSC SIS---------WLVHLFLNIMIPVRMSGPRYNKNVTN-WMDYEYCSWF-TPGNIGTALY MFLLSFSDVLCL-----------GLMA-CSSVSMVSILYRHKKQ----VKHIRSSQQV-- ---LNASPENRATQTILILVCTFVI---SYSFSSIVTVFISY------------SKHQ-- --MLL-----------GVS------------------LFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ITN------IKPG------- ----F-NLFLSCF-------------------------WKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >242-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAFE---------NFAV---GI---------FLFS------------- ---QITVGML------------GNSLILFYYITVITTG---K-----PLMPKDL-IIEHL -------TFANCLSVISKGIPQTL------------SDYGFKDFLDDIACKLINFIYRI- ---TRGMSLYSMCLLSCF-------QAITISPRNS-RWM-ILKRRAT------KYIGPSC SVG---------WLVHLFLNIMTPVRVSGPRYNKNVTM-IMDYEYCSWF-AHGNVGTALY MFLLSSSDVLCL-----------GLMA-CSSVSMVTILYRHKKQ----VKHIHSSQHI-- ---LNASPENRATLTILILVCTFVI---SYSFSSIVTVFTSY------------SKHQ-- --MLL-----------GVS------------------VFTFLEI---------------- ---G--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ITN------IKPG------- ----F-NLFLSCF-------------------------CKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >242-s -MS----------------K-----SV-----------------STQFQQRFT------- ------------------------S----------------------------QGE---- ---------------------------------------------------RHNHGINK- -------HRRKKMAFE---------NFAM---GI---------FLFS------------- ---QITVGML------------GNSSILFYYIILISTG---K-----PLMPKDL-IIEHL -------TFANCLSVISKGIPQTL------------SDYGFKDSLDDIGCKLINFIYRI- ---TRGMSLYTMCLLSCF-------QAITISPSNS-RWM-ILKHRAT------KYIGPSC SVS---------WLVHLFLNIMTPVRVSGPRYNKNVTN-WMDYEYCSWF-AHGNAGTALY MFLLSFSDVLCL-----------GLMA-CSSVSMVSILYRHKKQ----VKHIRRSQHV-- ---LNASPENRATQTILILVCTFVI---SYSFSSIVTVFTSY------------SKHQ-- --MLL-----------GVS------------------LFTFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ITN------MH-G------- ----M-EGVLSCL-------------------------LDSGSCPSYSPN---NPHRRGM AISHL----------------------GIAPSLPT------CI----------------- ------------------------------------------------------------ ------------- >242.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAFE---------NFAM---GI---------FLFS------------- ---QITVGML------------GNSSILFYYIILISTG---K-----PLMPKDL-IIEHL -------TFANCLSVISKGIPQTL------------SDYGFKDFLDDIGCKLINFIYRI- ---TRGMSLYTMCLLSCF-------QAITISPSNS-RWM-ILKHRAT------KYIGPSC SVS---------WLVHLFLNIMTPIRVSGPRYNKNVTN-WMDYEYCSWF-AHGNVGTALY MFLLSFSDVLCL-----------GLMA-CSSVSM-------------------------- ------------------------------EF---------------------------- ------------------------------------------------------------ ------FP-----------------------C-A--H---P------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >242.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------M---GI---------F---------------- ----------------------GNSSILFYYVILIFTG---K-----HLTPKDL-IIEHL -------TFANCLSIISKGIPQTL------------SDLGFKNFLDDIGCKLIMYIYRI- ---VRGMSLYAMCLLSCF-------QAITISPSNS-RWM-ILKHRAT------KYIGPSC SVS---------WLVHLFLNIMTPIRVSGPRYNKNVTN-WMDYEYCSWF-AHGNVGTALY MFLLSFSDVLCL-----------GLMA-CSSVSM-------------------------- ------------------------------EF---------------------------- ------------------------------------------------------------ ------FP-----------------------C-A--H---P------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >73-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MASE---------NFAM---GI---------FLFS------------- ---QTTVGML------------GNSSILFYYVILISTG---K-----PLMPKDL-IIEHL -------TFANCLSVISKGIPQTL------------LNYGFKDFLDDIGCKLINYVYRI- ---TRGMSLYSMCILSCF-------QAITISPNNY-RWV-TLKQRAT------KYIGPSC SVG---------WLVHLFLNIMIPVRVSGPRYNKNVTK-WKIYEYCSWF-TFGNVGDALY MFLLCFSDGLCL-----------GLMA-CSSVSMVSILYRHKRQ----VKYIHSSQQF-- ---LNASPENRATQSILILVCTFVI---SYLFSSIMVIFMSY------------SKYP-- --MLL-----------RVS------------------VFTFLET---------------- ---C--FP-----------------------I-V--C---P--------------FV--- --------L-------------------------------MSN------IKPS------- ----F-SLFLSCF-------------------------CK-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >73-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MASE---------NFAM---GI---------FLFS------------- ---QTTVGML------------GNSSILFYYIILISTG---K-----PLMPKDV-IIEHL -------TFANCLSVISKGIPQTL------------LNYGFKDFLDDIGCKLINYVYRI- ---TRGMSLYSMCILSCF-------QAITISPNNY-RWV-TLKQRAT------KYIGPSC SVG---------WLVHLFLNIMIPLRVSGPRYNKNVTK-WKIYEYCSWF-TFGNVGDALY MFLLCFSDGLCL-----------GLMA-CSSVSMVSILYRHKRQ----VKYIHSSQHF-- ---LNASPENRATQSILILVCTFVI---SYLFSSIMVIFMSY------------SKYP-- --MLL-----------RVS------------------VFTFLET---------------- ---C--FP-----------------------I-I--C---P--------------FV--- --------L-------------------------------MSN------IKPS------- ----F-SLFLSCF-------------------------CK-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >73-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MASE---------NFAM---GI---------FLFS------------- ---QTTVGML------------GNSSILFYYIILISTG---K-----PLMPKDV-IIEHL -------TFANCLTVISKGIPQTL------------LTYGFKDFLDDIGCKLINYVYRI- ---TRGMSLYSMCILSCF-------QAITISPNNY-RWV-TLKQRAT------KYIGPSC SVG---------WLVHLFLNIMIPLRVSGPRYNKNVTK-WKIYEYCSWF-TFGNVGHALY MFLLCFSDVLCL-----------GLMA-CSSVSMVSILYRHKRQ----VKYIHSSQHF-- ---LNASPENRATQSILILVCTFVI---SYLFSSIMVIFMSY------------SKYP-- --MLL-----------RVS------------------VFTFLET---------------- ---C--FP-----------------------I-I--C---P--------------FV--- --------L-------------------------------MSN------IKPS------- ----F-SLFLSCF-------------------------CK-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >73-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MASE---------NFAM---GI---------FLFS------------- ---QTTVGML------------GNSSILFYYIILISTG---K-----PLMPKDV-IIEHL -------TFANCLTVISKGIPQTL------------LTYGFKDFLDDIGCKLINYVYRI- ---TRGMSLYSMCILSCF-------QAITISPNNY-RWV-TLKQRAT------KYIGPSC SVG---------WLVHLFLNIMIPLRVSGPRYNKNVTK-WKIYEYCSWF-TFGNVGHALY MFLLCFSDGLCL-----------GLMA-CSSVSMVSILYRHKRQ----VKYIHSSQHF-- ---LNASPENRATQSILILVCTFVI---SYLFSSIMVIFMSY------------SKYP-- --MLL-----------RVS------------------VFTFLET---------------- ---C--FP-----------------------I-I--C---P--------------FV--- --------L-------------------------------MSN------IKPS------- ----F-SLFLSCF-------------------------CK-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >73-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MASE---------DFAM---GI---------FLFS------------- ---QTTVGML------------GNSSILFYYIILISTG---K-----PLMPKDV-IIEHL -------TFANCLSVISKGIPQTL------------LNYGFKDFLDDIGCKLINYVYRI- ---TRGMSLYSMCILSCF-------QAITISPNNY-RWV-TLKQRAT------KYIGPSC SVG---------WLVHLFLNIMIPLRVSGPRYNKNVTK-WEIYEYCSWF-TFGNVGAALY MFLLCFSDGLCL-----------GLMT-CSSVSMVSILYRHKRQ----VKYIHSSQHF-- ---LNASPENRATQSILILVCTFVI---SYLFSSIMVIFMSY------------FKYP-- --MLL-----------RVS------------------VFTFLET---------------- ---C--FP-----------------------I-I--C---P--------------FV--- --------L-------------------------------MSN------IKPS------- ----F-SLFLSCF-------------------------CK-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >73-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MASE---------NFAM---GI---------FLFS------------- ---QTTVGIL------------GNSSILFYYIILISTG---K-----PLMPKDL-IIEHL -------TFANCLSVISKGIPQTL------------LNYGFKDFLDDIGCKLINYVYRI- ---TRGMSLYAMCILSCF-------QAITISPNNS-WLV-ILKHRAT------KYIGPSC SVG---------WLVHLFLNIITPVRASGPRYNKNVTK-WKIYEYCSWF-TSGNVGDALY IFLLCLSDGLCL-----------GLMA-CSSVSMVSILYRHKRQ----VKYIHSTQHF-- ---LNTSPENRATQSILILVCTFVI---SYLLSSIMVIFMSY------------SKYP-- --MLL-----------RVS------------------VFTFLET---------------- ---G--FP-----------------------I-V--C---P--------------FV--- --------L-------------------------------MSN------IKPS------- ----F-SLSLSCF-------------------------CK-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >83-c -MC--------------YLQ----------------------------------EHKHTV ---VFSYE-------------VC-P----------------------------------- --------------------------------HIPL------YFWR------IDTGMK-- ------------MTSA---------NLVV---GI---------LLFS------------- ---QIVMGML------------GNSSILFYYAILIFTG---K-----HLMPKDL-IIEHL -------TFANCLSIISKGIPQTL------------SDLGFKNFLDDIGCKLIMYIYRI- ---VRGMSLYAMCLLSCF-------QAITISSRNS-RLM-ILKHKAT------KYIGPSC LVS---------WLVHLLLNIMTPVKVIGPISSKNVTN-MMSYGYCSWF-TSNNVATALY MFLLCFCDGLCL-----------SLMT-CSSVSMVSILYKHKRQ----VKHIHSAQQF-- ---LKVLPEDKATQIILILVCTFVI---SYSISSIRVIFTTY------------SEGS-- --VLW-----------GVS------------------VFIFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------IKCS------- ----F-KLFIPCC-------------------------GKR------------------- -------------------------------YLPPNIT---------------------- ------------------------------------------------------------ ------------- >83-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTSA---------NLAV---GI---------LLFS------------- ---QIVMGML------------GNSSILFYYVILIFTG---K-----HLMPKDL-IIEHL -------TFANCLSIISKGIPQTL------------SDLGFKNFLDDIGCKLIMYIYRI- ---VRGMSLYAMCLLSCF-------QAITISPRNS-RLM-ILKHRAM------KYIGPSC LVS---------WLVHLLLNIMTPVKVIGPIYSKNVTN-MMSYGYCSWF-TSSNVATALY MFLLCFCDGLCL-----------SLMT-CSSVSMVNILYKHKRQ----VKHIHSAQQF-- ---LKVLPEDKATQIILILVCTFVI---SYSISSIRVIFTSY------------SEGS-- --VLW-----------GVS------------------VFIFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------IKCS------- ----F-KLFLPCC-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >83.1-s -ML--------------WVKMVSRVRP-----------------RALILGEVG-YHPHAA DRLLWRWE-----------STVCGP----------------------------QGNAGVR ----LVGSSFSALQTPLSAAEELRMEWGILLQHFSLIISVDDYMIRDAEAPQLELGMK-- ------------MTSS---------NLVV---GI---------LLFS------------- ---QIVMGML------------GNSSILFYYVILIFTG---K-----HLTPKDL-IIEHL -------TFANCLSIISKGIPQTL------------SDLGFKNFLDDIGCKLIMYIYRI- ---VRGMSLYAMCLLSCF-------QAITISSRNS-RLM-ILKHRAM------KYIGPSC LVS---------WLVHLLLNIMTPVKVIGPISSKNVTN-VMSYGYCSWF-TSSNVATVLY MFLLCFCDGLCL-----------SLMT-CSSVSMVNILYKHKRQ----VKHIHSAQQL-- ---LKVLPEDKATQIILTLVCTFVI---SYSISSIRVIFTTY------------SEGS-- --VLW-----------GVS------------------VFIFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------IKCS------- ----F-KLLLPCC-------------------------GKR------------------- -------------------------------YLPPNIT---------------------- ------------------------------------------------------------ ------------- >83-x ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MIRDAETPQLELGMK-- ------------MTSS---------NLVV---GI---------LLFS------------- ---QIVMGML------------GNSSILFYYVILIFTG---K-----HLTPKDL-IIEHL -------TFANCLSIISKGIPQTL------------SDLGFKNFLDDIGCKLIMYIYRI- ---VRGMSLYAMCLLSCF-------QAITISSRNS-RLM-ILKHRAM------KYIGPSC LVS---------WLVHLLLNIMTPVKVIGPISSKNVTN-VMSYGYCSWF-TSSNVATALY MFLLCFCDGLCL-----------SLMT-CSSVSMVNILYKHKRQ----VKHIHSAQQL-- ---LKVLPEDKATQIILTLVCTFVI---SYSISSIRVIFTSY------------SEGS-- --VLW-----------GVS------------------VFIFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------IKCS------- ----F-KLFLPCC-------------------------SKR------------------- -------------------------------YLPPNII---------------------- ------------------------------------------------------------ ------------- >83.2-s -MISCC-----------GLKWCPASGP-----------------GLWILGEVG-YHPHAA DRLLWRWE-----------STVCGP----------------------------QGNAGVR ----LVGSSFSALQTPLSAAEELRMEWGILLQHFSLIISVDDYMIRDAEAPQLELGMK-- ------------MTSS---------NLVV---GI---------LLFS------------- ---QIVMGML------------GNSSILFYYVILIFTG---K-----HLTPKDL-IIEHL -------TFANCLSIISKGIPQTL------------SDLGFKNFLDDIGCKLIMYIYRI- ---VRGMSLYAMCLLSCF-------QAITISSRNS-RLM-ILKHRAM------KYIGPSC LVS---------WLVHLLLNIMTPVKVIGPISSKNVTN-VMSYGYCSWF-TSSNVATVLY MFLLCFCDGLCL-----------SLMT-CSSVSMVNILYKHKRQ----VKHIHSAQQL-- ---LKVLPEDKATQIILTLVCTFVI---SYSISSIRVIFTTY------------SEGS-- --VLW-----------GVS------------------VFIFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------IKCS------- ----F-KLLLPCC-------------------------GKR------------------- -------------------------------YLPPNIT---------------------- ------------------------------------------------------------ ------------- >83-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MTSS---------NLVV---GI---------LLFS------------- ---QIVMGML------------GNSSILFYYVILIFTG---K-----HLTPKDL-IIEHL -------TFANCLSIISKGIPQTL------------SDLGFKNFLDDIGCKLIMYIYRI- ---VRGMSLYAMCLLSCF-------QAITISSGNS-RLM-ILKHRAV------KYVGPSC LVS---------WLVHLLLNIMTPVKVIGPISSKNVTN-VMSYGYCSWF-TSSNVATALY MFLLCFCDGLCL-----------SLMT-CSSVSMVNILYKHKRQ----VKHIHSAQQL-- ---LKVLPEDKATQIILTLVCTFVI---SYSISSIRVIFTTY------------SEGS-- --VLW-----------GVS------------------VFIFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------IKCS------- ----F-KLFLPCC-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >81-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------MYIYRV- ---TRGMSLYAMCLLSCF-------QAITISPSNS-RWM-MLKHRAT------KYIGSSC LVS---------WLMQLLLNIMTLVKVTVPTYSKNVTN-TNSYGYCSWF-APSNLSTALY MFLLCFCDGLCL-----------SLMA-CSSVSMVNILYNHKRK----VKHIHSAQHL-- ---LKVSPEDRATKTVLILVCTFII---SYTISSIRVIFTTY------------SKVS-- --VIW-----------RVS------------------VFIFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------IKCS------- ----F-RLFLPFC-------------------------GKK------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >81.2-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MTSI---------NLPM---GI---------FLFS------------- ---QIVMGIF------------GNSSILFYYVIFIFSG---K-----HLMPKDM-IIEHL -------TLSNCLSLISKGIPQTL------------SDFGFKNFLDDIGCKVIMYIYRV- ---TRGMSLYAMCLLGCF-------QAITISPSNS-RWI-MLKHRAT------KYIGSSC LVS---------WLVNLLLNIMTLVKVTVPTYSKNVTN-TNSYGYCSWF-APSNLATALY MFLLCFCDGLCL-----------SLMA-CSSVSMMNILYKHKRQ----VKHIHSAQHL-- ---LKVSPEDRATQTILILVCTFII---SYTISSLRVIFTTY------------SNVS-- --EIW-----------RVS------------------VFIFLEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ISN------IKCS------- ----F-RLFLPFC-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >81.1-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MTSI---------NLPM---GI---------FLFS------------- ---QIVMGIF------------GNSSILFYYVIFIFSG---K-----HLMPKDM-IIEHL -------TLSNCLSLISKGIPQTL------------SDFGFKNFLDDIGCKVIMYIYRV- ---TRGMSLYAMCLLGCF-------QAITISPSNS-RWI-MLKHRAT------KYIGSSC LVS---------WLVNLLLNIMTLVKVTVPTYSKNVTN-TNSYGYCSWF-APSNLATALY MFLLCFCDGLCL-----------SLMA-CSSVSMMNILYKHKRQ----VKHIHSAQHL-- ---LKVSPEDRATQTILILVCTFII---SYTISSLRVIFTTY------------SNVS-- --EIW-----------RMNPHRYKQK---YHKHSYFYTYYYIHV---------------- ---C--MP-----------------------L-FL-C----------------------- --------------------------------------------------VCE------- ----F-FLHVCLCTTWIKYLQWSL-------------DGIKPC----------------- ------------------------------TCLCVNIGWWN------------------- ------------------------------------------------------------ ------------- >81-z -MA--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------QYVIDAVTLRLETGMK-- ------------MTSI---------NLPM---GI---------FLFS------------- ---QIVMGIF------------GNSSILFYYVIFIFSG---K-----HLMPKDM-IIEHL -------TLSNCLSLISKGIPQTL------------SDFGFKNFLDDIGCKVIMYIYRV- ---TRGMSLYAMCLLSCF-------QAITISPSNS-RWI-MLKHRAT------KYIGSFC LVS---------WLVNLLLNIMTLVKVTVPTYSKNVTN-TNSYGYCSWF-APSNLATALY MFLLCFCDGLCL-----------SLMA-CSSVSMMNILYK-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >78-s -----------------------------------------------MDTQFN--FKVVI IINLFT------------------------------------------------------ ----------------------------------------------------LLIGMK-- ------------MTPA---------NLAT---GI---------FFFF------------- ---HITVGIL------------GNSSILFHYVFMITTR---K-----HLMPKDV-IIKHL -------TFANCLTIISKGIPETL------------SNLGFKYFLDDIGCKLVVYIYRI- ---MRGMSLYAMCLLSCF-------QAITISPSNT-RWI-MFKHRAT------KYIGPSC SVS---------WLVYMLLNILIPARVLGPSYNKNVTN-MVNYGYCSWF-TSRNVATALY MFLLCFSDGLCL-----------GLMT-CSSISMVSVLYRHKRQ----VKHIHSAQHF-- ---LKVSPEDQATKTILSLVCTFVI---SYSISSIHVIFTVY------------FKGS-- --GLW-----------GVS------------------MFIFLEL---------------- ---C--FP-----------------------I-Y--F---P--------------FV--- --------L-------------------------------ITN------FKSS------- ----C-SLFLSFC-------------------------KKR------------------- -------------------------------WLPSNIA---------------------- ------------------------------------------------------------ ------------- >78-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MTPA---------SLAT---GI---------FFFF------------- ---HITVGIL------------GNSSILFHYVFMITTR---K-----HLMPKDV-IIKHL -------TFANCLTIISKGIPETL------------SDLGFKYFLDDIGCKLVVYIYRI- ---MRGMSLYAMCLLSCF-------QAITISPSNT-RWI-MFKHRAT------KYIGPSC SVS---------WLVYMLLNILTPARVLGPSYNKNVTN-MVNYGYCSWF-TSRNVATALY MFLLCFSDGLCL-----------GLMA-CSSISMVSVLYRHKRQ----VKHIHSAQHF-- ---LKVSPEDQATKTILILVCTFVI---SYSISSIHVIFTVY------------FKGS-- --GLW-----------GVS------------------MFIFLEL---------------- ---C--FP-----------------------I-Y--F---P--------------FV--- --------L-------------------------------ITS------FKSS------- ----C-SFFLSFC-------------------------KKR------------------- -------------------------------WLPSNIA---------------------- ------------------------------------------------------------ ------------- >78-x ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MTPA---------NLAT---GI---------FFFF------------- ---HITVGIL------------GNSSILFHYVFMITTR---K-----RLMPKDV-IIKHL -------TFANCLTIISKGIPEAL------------SDLGFKYFLDDIGCKLVVYIYRI- ---MRGMSLFAMCLLSCF-------QAITISHSNT-RWI-MFKHRAT------KYIGPSC SVS---------WLVYMLLNILTPARVLGPSYSKNVTN-MVNYGYCSWF-TSRNVATALY MFLLCFSDGLCL-----------GLMA-CSSISMVSVLYRHKRQ----VKHIHSAQHF-- ---LKVSPEDQATKTIFILVCTFVI---SYSISSIHVIFTVY------------FKGS-- --GLW-----------GVS------------------MFIFLEL---------------- ---C--FP-----------------------I-Y--F---P--------------FV--- --------L-------------------------------ITN------LKSS------- ----C-SLFLSFC-------------------------NKR------------------- -------------------------------WLPSNIA---------------------- ------------------------------------------------------------ ------------- >78-z -----------------------------------------------MDTQFN--FKVVI ILNLFT------------------------------------------------------ ----------------------------------------------------LLIGMK-- ------------MTPA---------NLAT---GI---------FFFF------------- ---HITVGIL------------GNSSILFHYVFMIITR---K-----RLMPKDV-IIKHL -------TFANCLTIISKGIPETL------------SDLGFKYFLDDIGCKLVVYIYRI- ---MRGMSLFAMCLLSCF-------QAITISHSNT-RWI-MFKHRAT------KYIGPSC SVS---------WLVYMLLNILTPARVLGPSYNKNVTN-MVNYGYCSWF-TSTNVATALY MLLLCFSDGLCL-----------GLMA-CSSISMVSVLYRHKRQ----VKHIHSAQHF-- ---LKVSPEDQATKTILILVCTFVI---SYSISSIHVIFTVY------------SKGS-- --GLW-----------GVS------------------MFIFLEL---------------- ---C--FP-----------------------I-Y--F---P--------------FV--- --------L-------------------------------ITN------LKSS------- ----C-GLFLSFC-------------------------NKR------------------- -------------------------------WLPSNIA---------------------- ------------------------------------------------------------ ------------- >75.1-c ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MR-- ------------MATR---------HFAM---GI---------FLFS------------- ---QITLGIL------------GNSSILFHYIFLILTG---K-----HLVPKDL-ILKHL -------TFANCLSIISRGIPRAM------------SDCGLKDFLDDIACKLIVYICRI- ---TRGMSLYAMCLLSCF-------QAITINPSNY-RCF-TLKHRAT------KYIGHCC SVS---------WLLHLFLNILTPARVSGPSYKKNVTN--MSYGYCSWI-ASDNVATALY MLLLCFSDALCL-----------TLMA-CSSVSMVSILYRHKRQ----VKHIHSVQHA-- ---LKDSPEDRATQTILILMCTFVL---SYSFSSIVVIFTTY------------SKYP-- --MLW-----------GVS------------------VLTFIEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------I-------------------------------ISN------MNFS------- ----S-SPFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >75.2-c ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MR-- ------------MATR---------HFAM---GI---------FLFS------------- ---QITLGIL------------GNSSILFHYIFLILTG---K-----HLVPKDL-ILKHL -------TFANCLSIISRGIPRAM------------SDCGLKDFLDDIACKLIVYICRI- ---TRGMSLYAMCLLSCF-------QAITINPSNS-RCF-TLKHRTT------KYIGHCC SVS---------WLLHLFLNILTPARVSGPNYKKNVTN--MSYGYCSWV-ASDNVATALY MLLLCFSDALCL-----------TLMA-CSSVSMVSILYRHKRQ----VKHIHSVQHA-- ---LKDSPEDRATQTILILMCTFVL---SYSFSSIVVIFTTY------------SKYP-- --MLW-----------GVS------------------VLTFIEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------I-------------------------------ISN------MNFS------- ----S-SPFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >75.1-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MR-- ------------MATR---------HFAM---GI---------FLFS------------- ---QITLGIL------------GNSSILFHYIFLILTG---K-----HLMPKDL-ILKHL -------TFANCLSIISRGIPRAM------------SDCGLKDFLDDIACKLIVYICRI- ---TRGMSLYAMCLLSCF-------QAITINPSNC-RCL-TLKHRAT------KYIGHCC SVS---------WLLHLFLNILTPARVSGPSYKKNVTN--MSYGYCSWV-ASGNVATALY MLLLCFSDALCL-----------TLMA-CSSVSMVSVLYRHKRQ----VKHIHSAQHA-- ---LKDSPEDRATQTILILMCIFVL---SYSFSSIVVILTTY------------SKYP-- --MLW-----------GVS------------------VLTFIEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------I-------------------------------ISN------MISS------- ----S-SPFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >75.1-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MR-- ------------MATR---------HFAM---GI---------FLFS------------- ---QITLGIL------------GNSSILFHYIFLILTG---K-----HLMPKDL-ILKHL -------TFANCLSIISRGIPRAM------------SDCGLKDFLDDIACKLIVYICRI- ---TRGMSLYAMCLLSCF-------QAITINPSNC-RCL-TLKHRAT------KYIGHCC SVS---------WLLHLFLNILTPARVSGPSYKKNVTN--MSYGYCSWV-ASGNVATALY MLLLCFSDALCL-----------TLMA-CSSVSMVSVLYRHKRQ----VKHIHSAQHA-- ---LKDSPEDRATQTILILMCIFVL---SYSFSSIVVILTTY------------SKYP-- --MLW-----------GVS------------------VLTFIEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------I-------------------------------ISN------MNSS------- ----S-SPFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >75.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------MPKDL-ILKHL -------TFANCLSIISRGIPRAM------------SDCGLKDFLDDIACKLIVYICRI- ---TRGMSLYAMCLLSCF-------QAITINPSNC-RCL-TLKHRAT------KYIGHCC SVS---------WLLHLFLNILTPARVSGPSYKKNVTN--MSYGYCSWV-ASGNVATALY MLLLCFSDALCL-----------TLMA-CSSVSMVSVLYRHKRQ----VKHIHSAQHA-- ---LKDSPEDRATQTILILMCIFVL---SYSFSSIVVILTTY------------SKYP-- --MLW-----------GVS------------------VLTFIEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------I-------------------------------ISN------MNSS------- ----S-SPFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >75.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MITLGIL------------GNSSILFHYIFLILTG---K-----HLMPKDL-ILKHL -------TFANCLSIISRGIPRAM------------SDCGLKDFLDDIACKLIVYICRI- ---TRGMSLYAMCLLSCF-------QAITINPSNC-RCL-TLKHRAT------KYIGHCC SVS---------WLLHLFLNILTPARVSGPSYKKNVTN--MSYGYCSWV-ASGNVATALY MLLLCFSDALCL-----------TLMA-CSSVSMVSVLYRHKRQ----VKHIHSAQHA-- ---LKDSPEDRATQTILILMCIFVL---SYSFSSIVVILTTY------------SKYP-- --MLW-----------GVS------------------VLTFIEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------I-------------------------------ISN------MISS------- ----S-SPFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >75-x ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MR-- ------------MATR---------HFAM---GI---------FLFS------------- ---QITLGIL------------VNSSILFHYIFLILTG---K-----HLMPKDL-ILKHL -------TFANCLSIISRGIPRAM------------SDCGLKDFLDDIACKLIVYICRI- ---TRGMSLYAMCLLSCF-------QAITINPSNC-RCL-TLKHRAT------TYIGHCC SVS---------WLLHLFLNILTPARVSGPSYKKNVTN--MSYGYCSWV-ASGNVATALY MFLLCFSDALCL-----------TLMA-CSSVSMVSVLYRHKRQ----VKHIHSAQHA-- ---LKDSPEDRATQTILILMCIFVL---SYSFSSIVVILTTY------------SKYP-- --MLW-----------GVS------------------VLTFIEI---------------- ---C--FP-----------------------I-F--C---P--------------FV--- --------I-------------------------------ISN------MISS------- ----S-NPILPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >75-p ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MR-- ------------MTTR---------LFAM---GI---------FLFS------------- ---QITLGIL------------GNSSILFHYIFLILTG---K-----HLMPKDL-ILKHL -------TFANCLSIISRGIPRAM------------SDCGLKDFLDDIACKLIVYICRV- ---TRGLSLYAMCLLSCF-------QAITINPSNS-RCL-TLKHRAN------KYIGHCC SVS---------WFLHLFLNILTPTRVSGPGYNKNVTN--MSYGYCSWV-ASGNVATALY MLLLCSSDVLCL-----------TLMA-CSSVSMVSILYRHKRQ----VKHIHSAQHA-- ---PKVSPEDRATQTILILMCIFVL---SYSFSSIVVIFTTY------------SKYP-- --MIW-----------GVS------------------VLTFIEI---------------- ---C--FP-----------------------I-F--C---P--------------FI--- --------I-------------------------------ISS------MNSS------- ----S-SPFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >73/242-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------M---GV---------FLFS------------- ---QITMGMI------------GNSSILLYYIILNFTR---K-----HLMPKDL-IIEHL -------IFANFLSIISRGIPKTL------------SAYGFKDFLDDIGCKLINYIYRI- ---TRGMSLYAMCLLSCF-------QAITINPSNS-RQM-IIKHKVT------KYIGPSC TVG---------WLVHLFLNVLTPARVSGPRYNKNVSM-RISYEYCSWF-ASGNVGTILY MFLLSFSDGLCL-----------GLMA-SSSTYMVSLLYRHKRK----VKHIHSSQHF-- ---LNVSPENKATQTILILVCMFIT---SYSFSSILIIFTTY------------SKYP-- --MLW-----------EVS------------------IFTFLEI---------------- ---W--FP-----------------------I-F--C---P--------------IV--- --------L-------------------------------IRN------MKPS------- ----F-SLLLPCF-------------------------VKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >73/242-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------M-IIKHKAS------KYIGPSC TVG---------WCVHLFLNVLTPVRVSGLRYNKNVST-RISYEYCSWF-ASGNVGTALY TFLLSFSDRLCL-----------SLMA-SSSTYMVSLLYRHKRK----VKHIHSSQHF-- ---LNVSPENKATQTILILICMFVT---SYSF--FLIVFATY------------SKYP-- --TLW-----------EVS------------------VFTFLEI---------------- ---C--FA-----------------------I-F--C---P--------------FV--- --------L-------------------------------IRN------MKPS------- ----L-PLLLPCF-------------------------VKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >77.1-c ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MISE---------NVTM---GI---------FLFC------------- ---QIIVGVL------------GNFSILFYYVILIFIG---K-----HLLPKDL-IIEHL -------TFSNCLTIILRGIPRTM------------SYFGFNVFLDDIGCKLIMYISRI- ---TRGMSMHATCILSCF-------QAITIRSSNF-KWM-KLKYKAT------KYIGPFC LVS---------WLFHLLLNILIPARVSGPSYKENVTN-RLSYEYCSLF-TSDHVGAALY MFLLCFSDVLCL-----------SLMA-CSSVSMVSTLYKHKRQ----VRNIHSAQHF-- ---QKVSPEDRASKNILILLCIFVI---SYSLSSLVAVIRTC------------SKYP-- --VPW-----------ALN------------------IFTLIEI---------------- ---C--FP-----------------------V-V--S---P--------------FV--- --------L-------------------------------ITN------MKLN------- ----F-SLFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >77-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------SHFGFNIFLDDIGCKLIMYISRI- ---TRGMSMYATCILSCF-------QAITIKSSNF-KWM-KLKYRAT------KYIGPFC LVS---------WLFHLLLNILIPARVSGPSYKENVTN-RLSYEYCSLF-TSDHVGAALY MFLLCFSDVLCL-----------SLMA-CSSVSMVSTLYKHKRQ----VRNIHSAQHF-- ---QKVSPEDRASKNILILLCIFVI---SYSLSSLVAVIRTC------------SKYP-- --VPW-----------ALN------------------IFTLIEI---------------- ---C--FP-----------------------V-V--C---P--------------FV--- --------L-------------------------------ITN------MKFN------- ----F-SLFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >77.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------SYFGFNIFLDDIGCKLIMYISRI- ---TRCMSMYATCILSCF-------QAITIRSSNF-KWM-KLKYRAT------KYIGPFC LVS---------WLFHLLLNILIPVRVSGPSSKENVTN-RLSYEYCSLF-TSDHVRAVLY MFLLCFSDVLCL-----------SLMA-CSSVSMVSTLYKHKRQ----VRNIHSAQHF-- ---QKVSPEDRASKIILIFLCIFVI---SYSLSSLVAVIRTC------------SKYP-- --VPW-----------ALN------------------IFTLIEI---------------- ---C--FP-----------------------V-V--C---P--------------FV--- --------L-------------------------------ITN------MKFN------- ----F-SLFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >77.2-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MISE---------NVTM---GI---------FLFC------------- ---QIIVGVL------------GNFSILFYYVILIFIG---K-----HLLPKDL-IIEHL -------TFANCLTIILRDIPRTM------------SYFGFNIFLDDIGCKLIMYISRI- ---TRCMSMYATCILSCF-------QAITIRSSNF-KWM-KLKYRAT------KYIGPFC LVS---------WLFHLLLNILIPVRVSGPSSKENVTN-RLSYEYCSLF-TSDHVRAVLY MFLLCFSDVLCL-----------SLMA-CSSVSMVSTLYKHKRQ----VRNIHSAQHF-- ---QKVSPEDRASKIILIFLCIFVI---SYSLSSLVAVIRTC------------SKYP-- --VPW-----------ALN------------------IFTLIEI---------------- ---C--FP-----------------------V-V--C---P--------------FV--- --------L-------------------------------ITN------MKFN------- ----F-SLFLPCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >77-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------MYISQI- ---TRGMPMYATCILSCF-------QAITIRSSNF-KWM-KLKYRAT------KYIGPFC LVS---------WLFHLLLNILIPARVPGPSYKENVTN-RLSYEYCSLF-TSDHVGAALY MFLLCFSDVLCL-----------SLMA-CSSVSMVSTLYKHKRQ----VRNIHSAQHF-- ---LKVSPEDRASKIILILLCIFVI---SYSLSSLVAVIRTC------------STYP-- --VPW-----------ALN------------------IFTLTEI---------------- ---I--FP-----------------------V-V--C---P--------------FV--- --------L-------------------------------ITN------MKFN------- ----F-SLFLLCF-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >77.2-c ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MISE---------NVTM---GI---------FLFC------------- ---QIIVGVL------------GNFSILFYYVILIFIG---K-----HLLPKDL-IIEHL -------TFSNCLTIILRGIPRTM------------SYFGFNVFLDDIGCKLIMYISRI- ---TRGMSMHATCILSCF-------QAITIRSSNF-KWM-KLKYKAT------KYIGPFC LVS---------WLFHLLLNILIPARVSGPSYKENVTN-RLSYEYCSLF-TSDHVGAALY MFLLCFSDVLCL-----------SLMA-CSSVSMLTT-------------HMHWWPS--- ----------------------VAL---LYSTCDDAAIERTMP---R-------TTHE-- --VPE-----------A------------------------------------------- ---------------------------------D--C---H--------------FCGLA SCQL--ESL-------------------------------TIS------SGLN------- ----YCCLVSAC------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >77.3-c ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MISE---------NVTM---GI---------FLFC------------- ---QIIVGVL------------GNFSILFYYVILIFIG---K-----HLLPKDL-IIEHL -------TFSNCLTIILRGIPRTM------------SYFGFNVFLDDIGCKLIMYISRI- ---TRGMSMHATCILSCF-------QAITIRSSNF-KWM-KLKYKAT------KYIGPFC LVS---------WLFHLLLNILIPARVSGPSYKENVTN-RLSYEYCSLF-TSDHVGAALY MFLLCFSDVLCL-----------SLMA-CSSVSMF----------------LHTY----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >77-p ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MPSE---------NFAM---GI---------FLSC------------- ---QIIVGIL------------GNSSIVFYYIILVFTG---K-----HLVPKDL-IIEHL -------TIANCLTIILRGIPQTM------------SYFGFKLFLDDIGCKLIVYISRV- ---TRGMSLYAMCLLSCF-------QAVTIRPSNS-RWT-KLKYRAT------NCIGPSC SVS---------WLFHLLLNILIATRVSGPTYKENVTN-RLSYAYCSLF-ASDIVETMLY MFILCFSDVLCL-----------CLMT-CSSVSMK------------------------- ---LTAVPRNKVTIQTFKLHC---------------------------------HDY--- ----W-----------TIS----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------CI-------------------------NDG------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >79-c ---------------------------------------------------MYYLQEQTH TVVMACE--------------AC------------------------------------- ---------------------PLR----------PL------YFW------KIDIGMK-- ------------MDPG---------NFAI---ET---------FLFC------------- ---QITVGMF------------GNSSILFYYIILIFTE---K-----HLTPKDL-IIEHL -------TFANYLTVILRGFPQTM------------AYFGFKNFLDDMGCKLIVYISRI- ---TRGMSLYAMCLLSCF-------QAITISPNNS-KWI-KLKYRAT------KYIGPSC SVS---------WLVHLLLNILTPLRVSGPNYKKNATN-RLSYGYCSLF-ASDSVATTLY ISLVCFSDVFCL-----------GLMA-CSSISMVSILYRHKRQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILLCTFVI---SYSFSSIVAMIRTY------------LKYP-- --VIW-----------GVN------------------IFTSLEI---------------- ---F--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ITN------MKSS------- ----F-NLFLLCL-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >79-s ------------------------------------------------------------ ---MACE--------------AC------------------------------------- ---------------------PLR----------PL------YFW------KIDIGMK-- ------------MDPG---------NFAI---ET---------FLFC------------- ---QITVGMF------------GNSSILFYYIILIFTE---K-----HLTPKDL-IIEHL -------TFANYLTVILRGFPQTM------------SYFGFKNFLDDRGCKLIVYISRI- ---TRGVSLYAMCLLSCF-------QAITISPNNS-RWI-KLKYRAT------KYIGPSC SVS---------WLVHLLLNILTPLRESGTNYKKNATN-RLSYGYCSLF-ASDSVATTLY ISLVCFSDVFCL-----------GLMA-CSSISMVSILYRHKRQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILLCTFVI---SYSFSSIVAIIRTY------------LNYP-- --VIW-----------GVN------------------IFTSLEI---------------- ---F--FP-----------------------M-F--C---P--------------FV--- --------L-------------------------------ITN------MRSS------- ----S-NLFLPCL-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >79-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MDPG---------NFAI---ET---------FLFC------------- ---QITVGMF------------GNSSILFYYIILIFTE---K-----HLTPKDL-IIEHL -------TFANYLTVILRGFPQTM------------SYFGFKNFLDDMGCKLIVYISRI- ---TRGVSLYAMCLLSCF-------QAITISPNNS-RWI-KLKYRAT------KYIGPSC SVS---------WLVHLLLNILTPLRESGTNYKKNATN-RLSYGYCSLF-ASDSVATTLY ISLVCFSDVFCL-----------GLMA-CSSISMVSILYRHKRQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILLCTFVI---SYSFSSIVAIIRTY------------LNYP-- --VIW-----------GVN------------------IFTSLEI---------------- ---F--FP-----------------------M-F--C---P--------------FV--- --------L-------------------------------ITN------MRSS------- ----S-NLFLPCL-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >79-x ---------------------------------------------------MYYLQEQTH TVVMACE--------------TC------------------------------------- ---------------------PLR----------PL------YFW------EIDIGMK-- ------------MDPG---------NFAI---ET---------FLFC------------- ---QITVGMF------------GNSSILFYYIILIFTE---K-----HLTPKDL-IIEHL -------TFANYLTVILRGFPQTM------------SYFGFKNFLDDIGCKLIVYISRI- ---TRGVSLYAMCLLSCF-------QAITISPNNS-RWI-KLKFRAT------KYIGPSC SVS---------WLVHLLLNILTPLRESGTNYKKNATN-RLSYGYCSLF-ASDSVATTLY ISLVCVSDVFCL-----------GLMT-CSSISMVSILYRHKRQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILLCTFVI---SYSFSSIVAIIRTY------------LNYP-- --VIW-----------GVN------------------IFTSLEI---------------- ---F--FP-----------------------M-F--C---P--------------FV--- --------L-------------------------------ITN------MRSS------- ----S-NLFLPCL-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >79-z -----------------------------------------------------------M DVQCLCD--------------RTY------------------------------------ --------------------SHLR--------------------------------MK-- ------------MDPG---------NFAI---ET---------FLFC------------- ---QITVGMF------------GNSSILFYYIILIFTE---K-----HLTPKDL-IIEHL -------TFANYLTVILRGFPQTM------------SYFGFKNFLDDMGCKLIVYISRI- ---TRGVSLYAMCLLSCF-------QAITISPNNS-RWI-KLKFRAT------KYIGPSC SVS---------WLVHLLLNILTPLRESGTNYKKNATN-RLSYGYCSLF-ASDSVATTLY ISLVCVSDVFCL-----------GVMA-CSSISMVSILYRHKRQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILLCTFVI---SYSFSSIVAVIRTY------------LNYP-- --VIW-----------GVN------------------IFTSLEI---------------- ---F--FP-----------------------M-F--C---P--------------FV--- --------L-------------------------------ITN------MRSS------- ----S-NLFLPCL-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >238-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MDPG---------NFAI---ET---------FLFC------------- ---QITVGMF------------GNSSILFYYFILIFTE---K-----HLTPKVL-IIEHL -------TFANYLTVILRGFPQTM------------SYFGFKNFLDDMECKLIVYISRI- ---TRGVSLYAMCLVSCF-------QAITISPNNS-RWI-KLKYRAT------KYIGPSC SVS---------WLVHLLLNILTPLRESGTNYKKNATN-RLSYGYCSLF-ASDSVATTLY ISLVCFSDVFCL-----------GLMA-CSSISMVSILYRHKRQ----VKHNHSAQHF-- ---LKVSPEDRATQTILILLCTFVI---SYSFSSIVAIIRTY------------LNYP-- --VIW-----------GVN------------------IFTSLEI---------------- ---F--FP-----------------------M-F--C---P--------------FV--- --------L-------------------------------ITN------MRSS------- ----S-NLFLPCL-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >3-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MGPG---------NFAI---ET---------FLFC------------- ---QITVGMF------------GNSSIPFYYIILIFTE---K-----HLTPKDL-IIEHL -------TFANYLTVILRGFPQTM------------SYFGFKNFLDDMGCKLLVYISRI- ---TRGVSLYAMCLLSCF-------QAITTSPNNS-RWI-KLKYRAT------KYIGPSC SVS---------CLVHLLLNILTPLRESGTNYKKNATN-RLSYGYCSLF-ASDSVATTLY ISLVCFSDVFCL-----------GLMA-CSSISMVSILYRHKRQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILLCTFVI---SYSFSSIVAIIRTY------------LNYP-- --VIW-----------GVN------------------IFTSLEI---------------- ---F--FP-----------------------M-F--C---P--------------FV--- --------L-------------------------------ITN------MRSS------- ----S-NLFLPCL-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >2-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ------------MDPG---------NFAI---ET---------FLFC------------- ---QITVGMF------------GNSSILFYYIILIFTE---K-----HLTSKDL-IIEHL -------TFANYLTVILRGFPQTM------------SYFGFKNFLDDMGCKLIVYISRI- ---TRGVSLYALCLLSCF-------QAITTSPNNS-RWI-KLKYRAT------KYIGPSC SVS---------CLVHLLLNILTPLRESGTNYKKNATN-RLSYGYCSLF-ASDSVATTLY ISLVCFSDVFCL-----------GLMA-CSSISMVSILYRHERQ----VKHIHSAQYF-- ---LKVYPEDRATQTILILLCTFVI---SYSFSSIVAIIRTY------------LNYP-- --VIW-----------GVN------------------IFTSLEI---------------- ---F--FP-----------------------M-F--C---P--------------FV--- --------L-------------------------------ITN------MRSS------- ----S-NLFLPCL-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >79-p ---------------------------------------------------MCYLQEQTH TVVMACE--------------TC------------------------------------- ---------------------SLR----------PL------HFW------KIDIGMK-- ------------MDPG---------NFAI---ET---------FLFC------------- ---QITVGMF------------GNSSILFYYIILIFTE---K-----HLTPKDL-IIEHL -------TFANCLTIILRGYPQTM------------TYFGFKNFLDDMGCKLIVYISRI- ---TRGMSLYAMCLLSCF-------QAITISPNNS-KWI-KLKYRAT------KYIGPSC SVS---------WLVHLLLNILTPLRVSGPNYKKNATN-RLNYGYCSLF-ASGSVATTLY ISLVCFSDVLCL-----------CLLA-CSSVSMVSILYKHKRQ----VKHIHSAQHF-- ---LNISPEDRATQTILILLCTFVI---SYSFSSIVAIIRTC------------LKYP-- --VIW-----------GVN------------------IITSLEI---------------- ---F--FP-----------------------I-F--C---P--------------FV--- --------L-------------------------------ITN------MKSS------- ----S-SLFLPCL-------------------------GKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >81-s ------------------------------------------------MQHFTRIHLHVR VRNL-------------------------------------------------------- ------------------------------------------------------LGMK-- ------------MTSI---------NLPM---GI---------FLFF------------- ---QILMGIF------------GNSSILFYYVIFIFSG---K-----YLMPKDM-IIEHV -------TLSNCLSLISKGIPQTL------------SDFGFKNFLGDIGCKVIMYIYRV- ---TRGMSLYAMCLLSCF-------QAITISPSNS-KWI-MLKHRAT------KYIGSSC LVS---------WLVNLLLNIMMLVKVTVPHLQQK------------------------- ------CD-------------------------------KHK------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >74.8-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MSLYAMCLLSCF-------QAITISPNYS-RWM-MFKHRAT------KYLGPSC SLS---------WLVQLFLNILAAARVSGPHYNKNTTN-RMNLGYCSSF-ASGNFATALY LFLLCFCDGLCL-----------GLMA-YSSVSMVSILYRHKKQ----VKHIHSAQHF-- ---LKVSPEDRATQTILILVCTFVL---SYSYSSILIIFTTY------------SKYP-- --MLWWLSSEFIKKYPRMSGHGRDPSLTIYFQGCTTNFMYFDHI---------------- ---C--EG-----------------------E-IV-C---Q--------------KVD-- --QLPRSDI-------------------------------MTH------VDSG------- ------N----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >82-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKPE---------NMVM---GI---------VFIL------------- ---QTTVGIL------------VNSSVLLHYLIPGFTG---K-----GLKLKTL-IVKHL -------TLANSLSIISRGIPQIM------------AEFGMKYFLDDIGCKLVLYLYRV- ---SRGGSLYTTCLLSCF-------QATIISSSST-KWM-KFKHKAI------KYMGPSC SLS---------WPMHLLLNVMILVAVTSSSNRRNATK-KLTYVYCSAS-VSGTVATPLY MLLLSFTDVLCL-----------SLMS-WASVFMLSILHRHKRQ----VQYIHGAQHS-- ---LRVSPEARATQTILILACTFVT---FYSISSIMVLYSAL------------FGNP-- --GLW-----------VIN------------------IISGLET---------------- ---C--YP-----------------------I-F--C---S--------------FV--- --------L-------------------------------ICN------NSSA------- ----S-RLYLPCW-------------------------WKH------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >82.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKPE---------NMVM---GI---------VFIL------------- ---QTTVGIL------------VNSSVLLHYLVPGFTG---K-----GLKLKTL-IVKHL -------TLANSLSIISRGIPQIM------------AEFGMKYFLDDIGCKLVLYLYRV- ---SRGVSLYTTCLLSCF-------QAAIISSSTT-KWM-KFKHKAI------KYMGPSC SLS---------WPMNLLLNVMILVTVTSSSNRRNATK-KLTYGYCSAS-VSGTIATPLY MLLLSFTDVLCL-----------SLMS-WASVFMLSILHRHKRQ----VQYIHGAQHS-- ---LRVSPEARATQTILILACTFVT---FYSISSIMVLYSAL------------FGNP-- --GLW-----------VIN------------------IISVLET---------------- ---C--YP-----------------------I-F--C---S--------------FV--- --------L-------------------------------ISN------NSSA------- ----S-RLYLHCW-------------------------WKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >82-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKPE---------NMVM---GI---------VFIL------------- ---QTTVGIL------------VNSSVLLHYLVPGFTG---K-----GLKLKTL-IVKHL -------TLANSLSIISRGIPQIM------------AEFGMKYFLDDIGCKLVLYLYRV- ---SRGVSLYTTCLLSCF-------QATIISSSTT-KWM-KFKHKAI------KYMGPSC SLS---------WPLNLLLNVMILVTVTSSSNRRNATK-KLTYGYCSAS-VSGTIATPLY MLLLSFTDVLCL-----------SLMS-WASVFILSILHRHKRQ----VQYIHGAQHS-- ---LRVSPEARATQTILILACTFVT---FYSISSIMVLYSAL------------FGNP-- --GLW-----------VIN------------------IISVLET---------------- ---C--YP-----------------------I-F--C---S--------------FV--- --------L-------------------------------ISN------NSSA------- ----S-RLYLHCW-------------------------WKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >82.2-m ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------K-- ------------MKPE---------NMVM---GI---------VFIL------------- ---QTTVGIL------------VNSSVLLHYLVPGFTG---K-----GLKLKTL-IVKHL -------TLANSLSIISRGIPQIM------------AEFGMKYFLDDIGCKLVLYLYRV- ---SRGVSLYTTCLLSCF-------QAAIISSSTT-KWM-KFKHKAI------KYMGPSC SLS---------WPMNLLLNVMILVTVTSSSNRRNATK-KLTYGYCSAS-VSGTIATPLY MLLLSFTDVLCL-----------SLMS-WASVFMLSILHRHKKQ----VQYIHGVQHF-- ---LRVSPEARATQTILILACTFVT---FYSISSIMVLYSAL------------FGNP-- --GLW-----------VIN------------------IISVLET---------------- ---C--YP-----------------------I-F--C---S--------------FV--- --------L-------------------------------ISN------NSSA------- ----S-RLYLHCW-------------------------WKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >82.3-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKPE---------NMVM---GI---------VFIL------------- ---QTTVGIL------------VNSSVLLHYLVPGFTG---K-----GLKLKTL-IVKHL -------TLANSLSIISRGIPQIM------------AEFGMKYFLDDIGCKLVLYLYRV- ---SRGVSLYTTCLLSCF-------QAAIISSSTT-KWM-KFKHKAI------KYMGPSC SLS---------WPMNLLLNVMILVTVTSSSNRRNATK-KLTYGYCSAS-VSGTIATPLY MLLLSFTDVLCL-----------SLMS-WASVFMLSILHRHKKQ----VQYIHGVQHF-- ---LRVSPEARATQTILILACTFVT---FYSISSIMVLYSAL------------FGNP-- --GLW-----------VIN------------------IISVLET---------------- ---C--YP-----------------------I-F--C---S--------------FV--- --------L-------------------------------ISN------NSSA------- ----S-RLYLHCW-------------------------WKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >82.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------M-KFKHKAI------KYMGPSC SLS---------WPMNLLLNVMILVTVTSSSNRRNATK-KLTYGYCSAS-VSGTIATPLY MLLLSFTDVLCL-----------SLMS-WASVFMLSILHRHKKQ----VQYIHGVQHF-- ---LRVSPEARATQTILILACTFVT---FYSISSIMVLYSAL------------FGNP-- --GLW-----------VIN------------------IISVLET---------------- ---C--YP-----------------------I-F--C---S--------------FV--- --------L-------------------------------ISN------NSSA------- ----S-RLYLHCW-------------------------WKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >82.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------M---------LYIV------------- ---KP----------------------------PGYS-----------IKVK-------- ------------------------------------------------------------ --------------------------------------Y-KFTPNVI------KYMGPSC SLS---------WPMNLLLNVMILVTVTSSSNRRNATK-KLTYGYCSAS-VSGTIATPLY MLLLSFTDVLCL-----------SLMS-WASVFMLSILHRHKRQ----VQYIHGAQHS-- ---LRVSPEARATQTILILACTFVT---FYSISSIMVLYSAL------------FGNP-- --GLW-----------VIN------------------IISVLET---------------- ---C--YP-----------------------I-F--C---S--------------FV--- --------L-------------------------------ISN------NSSA------- ----S-RLYLHCW-------------------------WKR------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >84-c ------------------------------------------------------MNTHLN AFFLGV------------------------------------------------------ ------------------------------------------LMWLN----MFIPGEK-- -----------NMAPE---------NLPV---GI---------LFFS------------- ---QTAVGIL------------GNWSILLHYVTSVING---K-----SLMPKDQ-ILKHL -------TLANSLVIISRVTPHIM------------VQLGLQYLLDDLLCKLTLYSNRV- ---SRGISLHCTCLLSCF-------QAITISLSHS-RLM-ALTHSVS------KYMIQFC SIS---------WLLHLLLNIKTAIDVIGPNTIKNVTR-KIMLGYCSAF-AFSNGVTGLH LFFVCFTDGLCL-----------SIMV-WASIFMVKILYRHKSQ----LQYIHSAHHP-- ---LRVSPEDKATKTILILVCTFVL---SYSMSFILIIYTVV------------FDNP-- --RLW-----------IIN------------------IFTFLDT---------------- ---C--FP-----------------------T-F--C---P--------------FI--- --------L-------------------------------ISN------NQST------P ------KNPLPCC-------------------------SRRNL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >84.1-s ------------------------------------------------------MNTHLN AFFLGV------------------------------------------------------ ------------------------------------------LMWLN----LSIPGEK-- -----------NMAPE---------NLPV---GI---------LFFS------------- ---QTAVGIL------------GNWSILLHYVTSVITG---K-----SLMPKDQ-ILKHL -------TLANSLVIISRVTPHIM------------VQLGLQYLLDDLLCKLTLYSNRV- ---SRGISLHCTCLLSCF-------QAITISLSHS-RLM-TLTHSVS------KYMIQFC SIS---------WLLHLLLNIKTAIDVIGPNTIKNVTR-KIMLGYCSAF-SFSNGVTGLH LFFVCFTDGLCL-----------SIMV-WASIFMVKILYRHKSQ----LQYIHSAHHP-- ---LRVSPEDKATKTILILVFTFVL---SYSMSFILIIYTVV------------FDNP-- --RLW-----------IIN------------------IFTFLDT---------------- ---C--FP-----------------------T-F--C---P--------------FI--- --------L-------------------------------ISN------NQST------P ------KNALPCC-------------------------SRRNL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >84.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAPE---------NLPV---GI---------LFFS------------- ---QTAVGIL------------GNWSILLHYVTSVITG---K-----SLMPKDQ-ILKHL -------TLANSLVIISRVTPHIM------------VQLGLQYLLDDLLCKLTLYSNRV- ---SRGISLHCTCLLSCF-------QAITISLSHS-RLM-TLTHSVS------KYMIQFC SIS---------WLLHLLLNIKTAIDVIGPNTIKNVTR-KIMLGYCSAF-AFSNGVTGLH LFFVCFTDGLCL-----------SIMV-WASIFMVKILYRHKSQ----LQYIHSAHHP-- ---LRVSPEDKATKTILILVFTFVL---SYSMSFILIIYTVV------------FDNP-- --RLW-----------IIN------------------IFTFLDT---------------- ---C--FP-----------------------T-F--C---P--------------FI--- --------L-------------------------------ISN------NQST------P ------KNALPCC-------------------------SRRNL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >84-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAPE---------NLPV---GI---------LFFS------------- ---QTAVGIL------------GNWSILLHYVTSVITG---K-----SLMPKDQ-ILKHL -------TLANSLVIISRVTPHIM------------VQLGLQYLLDDLLCKLTLYSNRV- ---SRGISLHCTCLLSCF-------QAITISLSHS-RLM-TLTHSVS------KYMIQFF SIS---------WLLHLLLNIKTAIDVIGPNTIKNVTR-KIMLGYCSAF-AFSNGVTGLH LFFVCFTDGLCL-----------SIMV-WASIFMVKILYRHKSQ----LQYIHSAHHP-- ---LRVSPEDKATKTILILVFTFVL---SYSMSFILIIYTVV------------FDNP-- --RLW-----------IIN------------------IFTFLDT---------------- ---C--FP-----------------------T-F--C---P--------------FI--- --------L-------------------------------ISN------NQST------P ------KNALPCC-------------------------SRRNL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >84-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAPE---------NLPV---GI---------LFFS------------- ---QTAVGIL------------GNWSILLHYVTSVITG---K-----SLMPKDQ-ILKHL -------TLANSLVIISRVTPHIM------------VQLGLQYLLDDLLCKLTLYSNRV- ---SRGISLHCTCLLSCF-------QAITISLSHS-RLM-TLTHSVS------KYMIQFF SIS---------WLLHLLLNIKTAIDVIGPNTIKNVTR-KIMLGYCSAF-AFSNGVTGLH LFFVCFTDGLCL-----------SIMV-WASIFMVKILYRHKSQ----LQYIHSAHHP-- ---LRVSPEDKATKTILILVFTFVL---SYSMSFILIIYTVV------------FDNP-- --RLW-----------IIN------------------IFTFLDT---------------- ---C--FP-----------------------T-F--C---P--------------FI--- --------L-------------------------------ISN------NQST------P ------KNALPCC-------------------------SRRNL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >84.2-m ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWLN----LFIPGEK-- -----------NMAPE---------NLPV---GI---------LFFS------------- ---QTAVGIL------------GNWSILLHYVTSVITG---K-----SLMPKDQ-ILKHL -------TLANSLVIISRVTPHIM------------VQLGLQYLLDDLLCKLTLYSNRV- ---SRGISLHCTCLLSCF-------QAITISLSHS-RLM-TLTHSVS------KYMIQFC SIS---------WLLHLLLNIKTAIDVIGPNTIKNVTR-KIMLGYCSAF-AFSNGVTGLH LFFVCFTDGLCL-----------SIMV-WASIFMVKILYRHKSQ----LQYIHSAHHP-- ---LRVSPEDKATKTILILVFTFVL---SYSMSFILIIYTVV------------FDNP-- --RLW-----------IIN------------------IFTFLDT---------------- ---C--FP-----------------------T-F--C---P--------------FI--- --------L-------------------------------ISN------NQST------P ------KNALPCC-------------------------SRRNL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >84-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAPE---------NLPV---GI---------LFFS------------- ---QTAVGIL------------GNWSILLHYVMSIITG---K-----SLMPKDQ-ILKHL -------TLANSLVIISRVTPHIM------------VQLGLQYLLDDLLCKLTLYSNRV- ---SRGISLHCTCLLSCF-------QAITINLSHS-RLM-TLTHFVS------KYMIQFC SIS---------WLLHLLLNIKTAVDVIGPNTIKNVTR-KIMLGYCSAF-AFGNGVTGLH LFFVCFTDGLCL-----------SIMV-WASIFMVKILYRHKSQ----LHYIHSAHHL-- ---LRVSPEDRATKTILILVCTFVL---SYSMSFILIIYTVV------------FDNP-- --RLW-----------IIN------------------IFTFLDT---------------- ---C--FP-----------------------T-F--C---P--------------FI--- --------L-------------------------------ISN------NQST------P ------KNPLSCC-------------------------SRRIFIMVT------------C VLC--------------------------------------------------------- ------------------------------------------------------------ ------------- >84.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAPE---------NLPV---GI---------LFFS------------- ---QTAVGIL------------GNWSILLHYVTSVITG---K-----SLMPKDQ-ILKHL -------TLANSLVIISRVTPHIM------------VQLGLQYLLDDLLCKLTLYSNRV- ---SRGISLHCTCLLSCF-------QAITISLSHS-RLM-TLTHSVS------KYMIQFC SIS---------WLLHLLLNIKTAIDVIGPNTKK-------------------------- ----------C-----------------------------------------HQENH--- ----------------------------------VGILFSIF------------FQQW-- --CYW------------------------------------------------------- -------P-----------------------T-FVLC---L--------------FH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >84.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAPE---------NLPV---GI---------LFFS------------- ---QTAVGIL------------GNWSILLHYVTSVITG---K-----SLMPKDQ-ILKHL -------TLANSLVIISRVTPHIM------------VQLGLQYLLDDLLCKLTLYSNRV- ---SRGISLHCTCLLSLLPSNHNQPQSLQADDTYT-LCL-KIHDSVL------LYKLAST SASKHQDSYRCDWTKYY---------------KK-------------------------- ----------C-----------------------------------------HQENH--- ----------------------------------VGILFSIF------------FQQW-- --CYW------------------------------------------------------- -------P-----------------------T-FVLC---L--------------FH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >235-c -M---------------ELKSVP-----------------------LKRSSAV-CFTLQS ASRV------------------CK------------------------------GN---- ---------------------SVS----------RM---------------WVQSSGN-- ----------DGMTAR---------NMAL---GI---------IFLS------------- ---QTALGLL------------GNSSVFFNYLLLYFSR---Y-----KLNSTDW-MLNYL -------VVANFLTLLCKGVPQTM------------AAFGLKDFLSDFGCNLLFYIHKM- ---GRGTCICSSSLMSAF-------QAITISNRNF-MWE-EFKTKSS------KFSGFFL CLC---------CILNILMSTYNLFYMTGKLGHRNMTI-IQDFGFC-SV-CLDKTGQILH TIFLPLPDVVYL-----------GLLV-WASISTVLILHRHKQR----LEHIPRNKHS-- ---SQSSTESRVIKTILLQLSTFML---FYIISCLFQLFLSF------------LHNP-- --SWL-----------LIN------------------ISIVISG---------------- ---C--FP-----------------------A-V--S---P--------------FL--- --------L-------------------------------MNQ-------YSI------A ----S-SHCVP---------------------------CMRN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >235.1-s ML---------------SVPHLP-----------------------LHDSQ--------- ------------------------------------------------------------ ----------------------------------------------------VQPSGN-- ----------DGMTAR---------NMAL---GI---------IFLS------------- ---QTALGLL------------GNSSVFFNYLLLYFSS---Y-----KLNSTDW-MLNYL -------VVANFLTLLCKGVPHIM------------AAFGLKDFLSDFGCNLLFYIHKM- ---GRGTCICSSSLMSVF-------QAITISNRNF-MWK-EFKAKSS------KFSGFFL CLC---------CTLNILMSTYNLFYMTGKLGHRNMTI-IQDFGFC-SV-CLDKTGQILH TIFLPVPDVVYL-----------GLLV-WTSISTVLILHRHKQR----LEHIPRNKHS-- ---SQSSTESRVIKTILLQLSTFML---CYIISCLFQLFLSF------------LHNP-- --SWL-----------LIN------------------ISIVISG---------------- ---C--FP-----------------------A-V--S---P--------------FL--- --------L-------------------------------MNH-------YSI------A ----S-SHCVP---------------------------CMRNWQNLI------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >235-m ML---------------SVPHLP-----------------------LHDSQ--------- ------------------------------------------------------------ ----------------------------------------------------VQPSGN-- ----------DGMTAR---------NMAL---GI---------IFLS------------- ---QTALGLL------------GNSSVFFNYLLLCFSR---Y-----KLNSTDW-MLNYL -------VVANFLTLLCKGVPQTM------------AAFGLKDFLSDFGCNLLFYIHKM- ---GRGTCICSSSLMSVF-------QAITISNRNF-MWK-EFKAKSS------KFSGFFL CLC---------CTLNILMSTYNLFYMTGKLGHRNMTI-IQDFGFC-SV-CLDKTGQILH TIFLPLPDVVYL-----------GLLV-WTSISTVLILHRHKQR----LEHIPRNKHS-- ---SQSSTESRVIKTILLQLSTFML---CYIISCLFQLFLSF------------LHNP-- --SWL-----------LIN------------------ISIVISG---------------- ---C--FP-----------------------A-M--S---P--------------FL--- --------L-------------------------------MNH-------YSI------A ----S-SHCVP---------------------------CMRNWQNLI------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >235-z ML---------------SVPHLP-----------------------LHDSQ--------- ------------------------------------------------------------ ----------------------------------------------------VQPSGN-- ----------DGMTAR---------NMAL---GI---------IFLS------------- ---QTALGLL------------GNSSVFFNYLLLYFSR---Y-----KLNSTDW-MLNYL -------VVANFLTLLCKGVPQTM------------AAFGLKDFLSDFGCNLLFYIHKM- ---GRGTCICSSSLMSVF-------QAITISNRNF-MWK-EFKAKSS------KFSGFFL CLC---------CTLNILMSTYNLFYMTGKLGHRNMTI-IQDFGFC-SV-CLDKTGQILH TIFLPLPDVVYL-----------GLLV-WTSISTVLILHRHKQR----LEHIPRNKHS-- ---SQSSTESRVIKTILLQLSTFML---CYIISCLFQLFLSF------------LHNP-- --SWL-----------LIN------------------ISIVISG---------------- ---C--FP-----------------------A-M--S---P--------------FL--- --------L-------------------------------MNH-------YSI------A ----S-SHCVP---------------------------CMRNWQNLI------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >235-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTAR---------NMAL---GI---------IFLS------------- ---QTALGLL------------GNSSVFFNYLLLYFSR---Y-----KLNSTDW-MLNYL -------VVANFLTLLCKGVPQTM------------AAFGLKDFLSDFGCNLLFYIHKM- ---GRGTCICSSSLMSFF-------QAIIISNRNF-MWK-EFKAKSS------KFSGFFL CLC---------CTLNILMSTYNLFYMTGKLGHRNMTI-IQDFGFC-SV-CLDKTGQILH TIFLPLPDVVYL-----------GLLV-WTSISTVLILHRHKQR----LEHIPRNKHS-- ---SQSSTESRVIKTILLQLSTFML---CYIISCLFQLFLSF------------LHNP-- --SWL-----------LIN------------------ISIVISG---------------- ---C--FP-----------------------A-M--S---P--------------FL--- --------L-------------------------------MNH-------YSI------A ----S-SHCVP---------------------------CMRNWQNLI------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >235.3-s -M---------------ELKSVP-----------------------LKRSSAV-CFTLQS ASRV------------------CK------------------------------GN---- ---------------------SVS----------RM---------------WVQPSGN-- ----------DGMTAR---------NMAL---GI---------IFLS------------- ---QTALGLL------------GNSSVFFNYLLLYFSS---Y-----KLNSTDW-MLNYL -------VVANFLTLLCKGVPHIM------------AAFGLKDFLSDFGCNLLFYIHKM- ---GRGTCICSSSLMSVF-------QAITISNRNF-MWK-EFKAKSS------KFSGFFL CLC---------CTLNILMSTYNLFYMTGKLGHRNMTI-IQDFGFC-SV-CLDKTGQILH TIFLPVPDVVYL-----------GLLV-WTSISTVLILHRHKQR----LEHIPRNKHS-- ---SQSSTESRVIKTILLQLSTFML---CYIISCLFQLFLSF------------LHNP-- --SWL-----------LIN------------------ISIVISG---------------- ---C--FP-----------------------A-V--S---P--------------FL--- --------L-------------------------------MNH-------YSI------A ----S-SHCVP---------------------------CMRNWQNLI------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >235.2-s ML---------------SVPHLP-----------------------LHDSQ--------- ------------------------------------------------------------ ----------------------------------------------------VQPSGN-- ----------DGMTAR---------NMAL---GI---------IFLS------------- ---QTALGLL------------GNSSVFFNYLLLYFSS---Y-----KLNSTDW-MLNYL -------VVANFLTLLCKGVPHIM------------AAFGLKDFLSDFGCNLLFYIHKM- ---GRGTCICSSSLMSVF-------QAITISNRNF-MWK-EFKAKSS------KFSGFFL CLC---------CTLNILMSTYNLFYMTGKLGHRNMTI-IQDFGFC-SV-CLDKTGQILH TIFLPVPDVVY-------------------------------------LEHIPRNKHS-- ---SQSSTESRVIKTILLQLSTFML---CYIISCLFQLFLSF------------LHNP-- --SWL-----------LIN------------------ISIVISG---------------- ---C--FP-----------------------A-V--S---P--------------FL--- --------L-------------------------------MNH-------YSI------A ----S-SHCVP---------------------------CMRNWQKPD------------M IRNI-------------------------------------------------------- ------------------------------------------------------------ ------------- >236.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------M---------IFIC------------- ---LTIIGIL------------GNFTLLYHYIYFYLTR---Y-----RLRSTDW-ILIHL -------IVANILTVLCKGVPQTI------------SSFGFTDFLNDIGCKLVSSLHRV- ---GRGASIGSTSLLSVF-------QAIVISPRNS-RDS-ELKVRTH------KCICCSV YLN---------WVIYLLISSVNLVHMRARYGNESTNN-LKSFIYCYSV-HHDPTSDILY ATLLSGPEVILL-----------GLML-WASGSMVLTLYRHKQM----MQYISRTSLS-- ---SRSSPESRATKTILLLVCTFVS---FYTISSACQSFGAL------------LYNP-- --KWS-----------LVN------------------MTAMTSL---------------- ---L--FP-----------------------T-V--C---P--------------FL--- --------H-------------------------------MSQ-------DSR------I ----S-SYL------------------------------KRNIHFP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >236.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MEAS---------ELSI---RM---------VFIF------------- ---LTTIGIL------------GNFTLLYHYIYFYLTR---Y-----RLRSTDW-ILIHL -------IVANILTVLCKGVPQTI------------SSFGFTDFLNDIGCKLVSSLHRV- ---GRGASIGSTSLLSVF-------QAIVISPRNS-RDS-ELKVRTH------KCICCSV YLN---------WLIYLFINSVNLVYLRARNGNESTTN-LKSFFFCYSV-RHDPTSDILY ATLLSSPEVILL-----------GLML-WASGSMVLTLYRHKQM----MQYISRTSLS-- ---SRSSPESRATKTILLLVCTFVS---FYTISSACQSFGAL------------LYNP-- --KWS-----------LVN------------------MTAMTSL---------------- ---L--FP-----------------------T-V--C---P--------------FL--- --------H-------------------------------MSQ-------DSR------I ----S-SYL------------------------------KRNIHFP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >236-s ------------------MDSFR-----------------------IENGDCVSTFTLPC RIL--------------------------------------------------------- ----------------------------------------------------SLRTRT-- ----------DSMEAS---------ELSI---GM---------IFIC------------- ---LTIIGIL------------GNLTLLYHYIYFYLTR---Y-----RLRSTDW-ILIHL -------IVANILTVLCKGVPQTI------------SSFGFTDFLNDIGCKLVSSLLRV- ---GRGAGIGSTSFLSVF-------QAIIISPRNS-RNS-ELKVRTH------KCICCSV YLN---------WVIYLLISSVNLVHMRARYGNESTTN-LKSFIYCYSV-RHDPTSDILY ATLLSGPEVLLL-----------GLML-WASGSMVLTLYRHKQM----MQYMSRTSLS-- ---SRSSPESRATKTILLLVCTFVS---FYTISSVCQSFGAL------------LYNP-- --SWF-----------LVT------------------MTAMSSL---------------- ---L--FP-----------------------I-V--C---P--------------FL--- --------L-------------------------------MSQ-------DSR------I ----F-S----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >236-x ------------------MDSFR-----------------------IENGDCVSTFTLPC RIL--------------------------------------------------------- ----------------------------------------------------SLRTRT-- ----------DSMEAS---------ELSI---GM---------IFIS------------- ---LTITGIL------------GNLTLLYHYIYFYLTR---Y-----RLRSTDW-ILIHL -------IVANILTVLCKGVPQTI------------SLFGFTDFLNDIGCKLVCSLRRV- ---GRGAGIGSTSFLSVF-------QAIIISPRNS-RNS-ELKVRTH------KCICCSV YLN---------WVIYLLISSVNLVHMRARYGNESTTN-LKSFIYCYSV-RHDPTSDILY ATLLSGPEVLLL-----------GLML-WASGSMVLTLYRHKQT----MQYMSRTSLS-- ---SRSAPESRATKTILLLVCTFVS---FYTISSVCQSFGAL------------LYNP-- --SWF-----------LVN------------------MTAMSSL---------------- ---L--FP-----------------------T-V--C---P--------------FL--- --------L-------------------------------MSQ-------DSR------I ----S-S----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >236-z ------------------MDSFR-----------------------IENGDCVSTFTLPC RIL--------------------------------------------------------- ----------------------------------------------------SLRTRT-- ----------DSMEAS---------ELSI---GM---------IFIS------------- ---LTITGIL------------GNLTLLYHYIYFYLTR---Y-----RLRSTDW-ILIHL -------IVANILTVLCKGVPQTI------------SLFGFTDFLNDIGCKLVCSLRRV- ---GRGAGIGSTSFLSVF-------QAIIISPRNS-RNS-ELKVRTH------KCICCSV YLN---------WVIYLLISSVNLVHMRARYGNESTTN-LKSFIYCYSV-RHDPTSDILY ATLLSGPEVLLL-----------GLML-WASGSMVLTLYRHKQM----MQYMSRTSLS-- ---SRSAPESRATKTILLLVCTFVS---FYTISSVCQSFGAL------------LYNP-- --SWF-----------LVN------------------MTAMSSL---------------- ---L--FP-----------------------T-V--C---P--------------FL--- --------L-------------------------------MSQ-------DSR------I ----S-S----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >236-m ------------------MDSFR-----------------------IENGDCVSTFTLPC RIL--------------------------------------------------------- ----------------------------------------------------SLRTRT-- ----------DNMEAS---------ELSI---GI---------IFIS------------- ---LTIIGIL------------GNVTLLYHYTYFYLTR---Y-----KLRSTDW-ILIHL -------IVANILTVLCKGVPQTI------------SSFGFKDFLNDIGCKLVSSLHRV- ---GRGTGIGSTSFLSVF-------QAIIISPRNS-RDS-ELKVRTH------KCICCSV YLN---------WVIYLLISSVNLVHMRARYGNESTTN-LKSFIYCYSV-RHDPTSDILY ATLLSGPEVLLL-----------GLML-WASGSMVLTLYRHKQM----MQYMSRTSLS-- ---SRSSPESRATKTILLLVCTFVS---FYTISSVCQSFGAL------------LYNP-- --KWS-----------LVN------------------ITAMSSL---------------- ---L--FP-----------------------T-V--C---P--------------FL--- --------L-------------------------------MSQ-------DSR------I ----S-SYL------------------------------KRNIHFP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >236-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MEAS---------ELSI---GM---------IFTS------------- ---LTIIGIL------------GNFTLLYHYMYIYITR---Y-----RIRSTDW-ILIHL -------IVANILTLLCKGVPQTI------------YSFGFKDFLDDIGCKLVSSFHRV- ---GRGAGIGSTSFLSVF-------QAIIIRPRNS-RDS-ELKVRTH------ECICCSV YLN---------WVIYLLISSINLVHMRAKHGNESTAN-LKSFMYCYSV-RHDPTSDILY TTLLSGPEVLLL-----------GLML-WASGSMVLTLYMHKQM----MQYMSRSSLS-- ---SRYSPVSRATKTILLLVCTFVS---FYTISCLCQSFGAL------------LYNP-- --SWF-----------VVN------------------ITAMSSL---------------- ---L--FP-----------------------A-L--C---P--------------FL--- --------L-------------------------------MSQ-------DSR------I ----S-SYL------------------------------KRNRHFP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >233/236-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MATC---------ELAV---GV---------IFLS------------- ---QTVIGVL------------GNFSLLCHYLFLYLIG---Y-----RLLSTDW-IVMHL -------TVANILTLLCKGVPQTI------------AGFGSKDFLNDIGCKLVFSFHRV- ---GRSVGVGSTSFLSVF-------QAIIIRLRNT-RSS-DFKVKTH------KCICYSV YLS---------WLIHFFISSVNLMHMRAKYINETTTE-LKSFLYCYWD-CHDKTRDILY AALLLAPDIIFL-----------GLMV-WASSCMVLTLYRHKQK----MQQMPRNKMS-- ---SKSSPESRATKTILLLVCTFVS---FYTLSSLCQLFGAL------------LYKP-- --SWS-----------LVN------------------VTAMASL---------------- ---L--FP-----------------------T-V--C---P--------------FL--- --------L-------------------------------MSR-------DSR------V ----S-SFFLP---------------------------STRNRTFPK------------T SEDE------------------------------IN------------------------ ------------------------------------------------------------ ------------- >233-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDTS---------ELSV---GV---------IILC------------- ---QTLIGVL------------ANSSLLYHYMFLYLTR---D-----RLRSTDW-ILMHL -------IAANILTVLFKGIPQTM------------AAFGLKDFLNDIGCKLIFSFRRI- ---GRGVCIGSTSFLSVY-------QAIMISPRDS-RYS-ELKLKMH------KCIGYSV YLN---------WVMHFIISSVNFVHMRAKYSNESTTN-LKSFIYCYAV-RHDPTSDILY AALVSSPDILLL-----------GLMI-YASGFMVLTLYRHKQR----MQQMPRINVS-- ---SKSSPASRATKTILLLVSIFVS---CYTISTICQLLATL------------MLNP-- --SWS-----------LAN------------------VAAMSSL---------------- ---V--FP-----------------------T-V--C---P--------------FL--- --------L-------------------------------VSH-------DLR------A ----S-NFCLS---------------------------LKRNI-FPK------------P VAKS-------------------------------------------------------- ------------------------------------------------------------ ------------- >233-s ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------MRGET-- ----------DCMDAS---------ELSV---GV---------IILF------------- ---QTMIGVL------------ANSSLLYHYMFLYLTR---D-----RLRSIDW-ILVHL -------IAANILTVLFKGIPQTI------------AAFGLKDFLNDIGCKLIFSFRRI- ---GRGVCIGSTSFLSVY-------QAIMISPRDS-RHS-ELKLKMH------KCIGYSV YLN---------WVIHFIISSVNLVHMRAKYSNESTTN-LKSFIYCYAV-RHDPTSDILY AALVSSPDILLL-----------GLML-YASGFMVLTLYRHKQR----MQQMPRMNVS-- ---SKSTPASRATKTILLLVSIFVS---CYTISTICQLLATL------------MHNP-- --SWS-----------LAN------------------VAAMSSL---------------- ---V--FP-----------------------T-V--C---P--------------FL--- --------L-------------------------------MSH-------DSR------A ----S-SFCLP---------------------------LKRNI-SPK------------P LAKS-------------------------------------------------------- ------------------------------------------------------------ ------------- >233-m ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------MRGGT-- ----------DCMDAS---------ELSV---GV---------IILF------------- ---QTMIGVL------------ANSSLLYHYMFLYLTR---D-----RLRSIDW-ILVHL -------IAANILTVLFKGIPQTI------------AAFGLKDFLNDIGCKLIFSFRRI- ---GRGVCIGSTSFLSVY-------QAIMISPSDS-RHS-ELKLKMH------KCIGYSV YLN---------WVIHFIISSVNLVHMRAKYSNESTTN-LKSFIYCYAV-RHDPTSDILY AALVSSPDILLL-----------GLML-YASGFMVLTLYRHKQR----MQQMPRMNVS-- ---SKSTPASRATKTILLLVSIFVS---CYTISTICQLLATL------------MHNP-- --SWS-----------LAN------------------VAAMSSL---------------- ---V--FP-----------------------T-V--C---P--------------FL--- --------L-------------------------------MSH-------DSR------A ----S-SFCLP---------------------------LKRNI-SPK------------P LAKS-------------------------------------------------------- ------------------------------------------------------------ ------------- >233-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDAS---------ELSV---GV---------IILF------------- ---QTMIGVL------------ANSSLLYHYMFLYLTR---D-----RLRSTDW-ILMHL -------IAANILTVLFKGIPQTI------------AAFGLKDFLNDIGCKLIFSFRRI- ---GRGVCIGSTSFLSVY-------QAIMISPRDS-RHS-ELKLKMH------KCIGYSV YLN---------WVIHFIISSVNLVHMRAKYSNESTTN-LKSFIYCYAV-RHDPTSDILY AALVSSPDILLL-----------GLML-YASGFMVLTLYRHKQR----MQQMPRMNVS-- ---SKSTPASRATKTILLLVSIFVS---CYTISTICQLLATL------------MHNP-- --SWS-----------LAN------------------VAAMSSL---------------- ---V--FP-----------------------T-V--C---P--------------FL--- --------L-------------------------------MSH-------DSR------A ----S-SFCLP---------------------------LKRNI-SPK------------P LAKS-------------------------------------------------------- ------------------------------------------------------------ ------------- >237-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MENS---------DIVI---SV---------IFLS------------- ---QTVVGIL------------GNSFLVYHYLMLYYMG---C-----RLKFTDW-ILQHL -------IVANFLTLLCKGIPHTV------------SAFGLKNFLDDIGCKLIFYLHRI- ---GRGVSISSTCFLSVF-------QAITLSPSAS-RWT-QLKAKSP------SYIASCV YMS---------WALSFLVNIAFPMYMRARQNNRNITR-LRVYDICSTV-HHDEVCDIIS AVLLSIPDVVFM-----------VLML-WSSGYMVCILYRHKQR----MKHIHRSTFS-- ---FRSSAEFRATKSILLLVSTFVF---FYTISCLFQINMAL------------FHNP-- --TSL-----------WVN------------------MASVVTA---------------- ---C--FP-----------------------T-V--S---P--------------FL--- --------V-------------------------------ISS----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >237-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MENS---------DIVI---SV---------IFLS------------- ---QTVVGIL------------GNSFLVYHYLMLYYMG---C-----RLKFTDW-ILQHL -------IVANFLTLLCKGIPHTV------------SAFGLKNFLNDIGCKLTFYLHRI- ---GRGVSISSTCFLSVF-------QAITISPSAS-R-T-QLKAKSP------SYIASCV YMS---------WALSFLVNIAFPMYMRARQNNRNITR-LRVYDICSTV-HHDKVSDIIN AVLLSIPDVVFM-----------VLMV-WSSGYMVCILYRHKQR----MKHIHRSTFS-- ---FRSSAEFRATKTILLLVSTFVI---FYTISCLFQINLAL------------FHNP-- --TSL-----------WVN------------------MASVVTA---------------- ---C--FP-----------------------T-V--S---P--------------FL--- --------V-------------------------------ISS----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >237-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MENS---------DIVI---SV---------IFLS------------- ---QTVVGIL------------GNSFLVYHYLMLYYMR---C-----RLKFTDW-ILQHL -------IVANFLTLLCKGIPHTV------------SAFGLKNFLDDIGCKLTFYLHRI- ---GRGVSISSTCFLSVF-------QAITISPSAS-RWT-QLKAKSP------SYIASCV YMS---------WALSFLVNIAFPMDMRARQNNRNITR-LRVYGICSTV-HHNKVSDIIN AVLLSIPDVVFM-----------VLMV-WSSGYMVCILYRHKQR----MKHIHRSTFS-- ---FRSSAEFRATKTILLLVSTFVF---FYTISCLFQINLAL------------FHNP-- --TSL-----------WVN------------------MASVVTA---------------- ---C--FP-----------------------T-V--S---P--------------FL--- --------V-------------------------------ISS----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >237-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MENS---------DIVI---SV---------IFLS------------- ---QTVVGIL------------GNSFLVYHYLMLYYMR---C-----RLKFTDW-ILQHL -------IVANFLTLLCKGIPHTV------------SAFGLKNFLNDIGCKLTFYLHRI- ---GRGVSISSTCFLSVF-------QAITISPSAS-RWT-QLKAKSP------SYIASCV YMS---------WALSFLVNIAFPMDMRARQNNRNITR-LRVYDTCSTV-HHNKVGDIIN AVLLSVPDVVFM-----------VLMV-WSSGYMVCILYRHKQR----MKHIHRSTFS-- ---FRSSAEFRATKTILLLVSTFVF---FYTISCLFQINLAL------------FHNP-- --TSL-----------WVN------------------MASVVTA---------------- ---C--FP-----------------------T-V--S---P--------------FL--- --------V-------------------------------ISS----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >237-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MENS---------DIVI---SV---------IFLS------------- ---QTVVGIL------------GNSFLVYHYLMLYYMR---C-----RLKFTDW-ILQHL -------IVANFLTLLCKGIPHTV------------SAFGLKNFLNDIGCKLTFYLHRI- ---GRGVSISSTCFLSVF-------QAITISPSAS-RWT-QLKAKSP------SYIASCV YMS---------WALSFLVNIAFPMDMRARQNNRNITR-LRVYDTCSTV-HHNKVGDIIN AVLLSVPDVVFM-----------VLMV-WSSGYMVCILYRHKQR----MKHIHRSTFS-- ---FRSSAEFRATKTILLLVSTFVF---FYTISCLFQINLAL------------FHNP-- --TSL-----------WVN------------------MASVITA---------------- ---C--FP-----------------------T-V--S---P--------------FL--- --------V-------------------------------ISS----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >237.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGYS---------DVVV---SV---------IFLS------------- ---QTVVGVL------------GNSFLAYHYLMLYFVG---C-----RLKFTDW-ILQHL -------IVANFLTLLCKGIPHTM------------SAFGLKVFLSDIGCKLIFYAHRI- ---GRGVSISSTCFLSVF-------QAITISPNAS-RWT-QLKVKSP------SYIASCV YMS---------WVLSFIVNIAFPMYMTARQDNRNISR-LRVYDFCSTV-HLDKITDILS AIFLPIPDVVFM-----------LLML-WSSGYMVCILYRHKQR----MKHIHRSTFS-- ---FRSSAEFRATKTILLLVSTFVF---FYTISCILQINMSL------------WHSP-- --TSL-----------WVN------------------MASVVAA---------------- ---G--FP-----------------------T-V--S---P--------------FL--- --------V-------------------------------ISN----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >237.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MENS---------DVVI---GV---------IFLS------------- ---QTIFGFL------------GNSFLVYHYLMLYFVG---C-----KLKFTDW-ILQHL -------IVANFLTLLCKGIPHTV------------SAFGLKDFLDDIGCKLIFYLHRI- ---GRGVSISSTCFLSVF-------QAITISPNAS-RWT-QLKVKSP------SYIASCV YMS---------WVLSFIVNIAFPMYMTARWYNRNITR-LRVFEFCSSV-QHDKTSDIVN AVFISIPDVLLV-----------VLML-WSSGYMVCILYRHKQR----MKHIHRSNFS-- ---FKSSAEFRATKIILLLVSTFVF---FYTISCILQINMSL------------THNP-- --NSL-----------WVN------------------MASIVAA---------------- ---C--FP-----------------------A-V--S---P--------------FL--- --------V-------------------------------ISRSLCSACAGNR------I ----S------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >234-c ------------------------------------------------MKQVVHAYLLMQ NPR--------------------------------------------------------- ----------------------------------------------------DQAEGS-- ----------RQIMSG---------DMAI---GV---------ILVS------------- ---QTVAGVL------------GNSCLLYNYIVLYFKS---Y-----KLKHMDW-ILTHL -------IVSNFLTLLCKGVPQAM------------AAFGFQCFFNDFECKLLSYLHRV- ---GRGVSFGSACLLSVF-------QVITISPEDA-IWT-IFKNKAP------KYISSSL YLT---------WILSLLFSIVSLKYMSAKLCNVNNTN-LKDLGYCSSL-FFDKTAEVLH AVHVIIPGAVCM-----------FFML-CSSGSMVLILHRHKQR----MEHMIRRNVF-- ---PRSSHESRATQTILLLVSTFVC---FYTLSTLLTICLNF------------LVNL-- --TWH-----------LVS------------------IHSIFSM---------------- ---C--FA-----------------------S-V--S---P--------------YL--- --------L-------------------------------MRH-------GSS------T ----S-IHCFAWV------------------------NYQKS------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >234-s ------------------------------------------------MKQVVHAYLLMQ NPR--------------------------------------------------------- ----------------------------------------------------DQAEGS-- ----------HQITSG---------DMAI---GV---------ILVS------------- ---QTVAGVL------------GNSCLLYNYIVLYFKS---Y-----KLKHMDW-ILMHL -------IVSNFLTLLCKGVPQAM------------AAFGFQCFFNDFECKLLSYLHRV- ---GRGVSFGSACLLSVF-------QVITISPEDA-IWT-IFKKKAP------KYISSSL YLT---------WILSLLFSIVSLKYMSAKLCNVNNTN-LKDLGYCSSL-SFDKTAEVLH AAHVIIPGAVCM-----------FFML-CSSGSMVLILHRHRQR----MEHMIRSNIF-- ---PRS------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >234-x ------------------------------------------------MKQVVHAYLLMQ SPR--------------------------------------------------------- ----------------------------------------------------DQAEGS-- ----------HQITSG---------DMAI---GV---------ILVS------------- ---QTVAGVL------------GNSCLFYNYVVLYFKS---Y-----KLKHMDW-ILMHL -------IVSNFLTLLCKGVPQAM------------AAFGFQCFFNDFECKLLSYLHRV- ---GRGVSFGSACLLSVF-------QVITISPEDA-IWT-IFKKKAP------KYISSSL YLT---------WILSLLFSIVSLKYMSAKLCNLNNTN-LKDLGYCSSL-SFDKTAEVLH AAHVIIPGAVCM-----------FFML-CSSGSMVLILHRHRQR----MEHMIRSNIF-- ---PRSSHESRATQTILLLVSTFVC---FYTLSTLLTICLNF------------LVNL-- --TWH-----------LVS------------------IHAIFSM---------------- ---C--FA-----------------------S-V--S---P--------------YL--- --------L-------------------------------MRH-------GSS------T ----S-IHCFAWV------------------------NYQKS------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >234-z ------------------------------------------------MKQVVHAYLLMQ NPR--------------------------------------------------------- ----------------------------------------------------DQAEGS-- ----------HQITSG---------DMAI---GV---------ILVS------------- ---QTVAGVL------------GNSCLLYNYIVLYFKS---Y-----KLKHMDW-ILMHL -------IVSNFLTLLCKGVPQAM------------AAFGFQCFFNDFECKLLSYLHRV- ---GRGVSFGSACLLSVF-------QVITISPEDA-IWT-IFKKKAP------KYISSSL YLT---------WILSLLFSIVSLKYMSAKLCNLNNTN-LKDLGYCSSL-SFDKTAEVLH AAHVIIPGAVCM-----------FFML-CSSGSMVLILHRHRQR----MEHMIRSNIF-- ---PRSSHESRATQTILLLVSTFVC---FYTLSTLLTICLNF------------LVNL-- --TWH-----------LVS------------------IHAIFSM---------------- ---C--FA-----------------------S-V--S---P--------------YL--- --------L-------------------------------MRH-------GSS------T ----S-IHCFAWV------------------------NYQKS------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >234-m ------------------------------------------------MKQVVHAYLLMQ NPR--------------------------------------------------------- ----------------------------------------------------DQAEGS-- ----------HQITSG---------DMAI---GV---------ILVS------------- ---QTVAGVL------------GNSCLLYNYIVLYFKS---Y-----KLKHMDW-ILMHL -------IVSNFLTLLCKGVPQAM------------AAFGFQCFFNDFECKLLSYLHRV- ---GRGVSFGSACLLSVF-------QVITISPEDA-IWT-ILKKKAP------KCISSSL YLT---------WILSLLFSIVSLKYMSAKLCNVNNTN-LKDLGYCSSL-SFDKTAEVLH AAHVIIPGAVCM-----------FFML-CSSGSMVLILHRHRQR----MEHMIRSNIF-- ---PRSSHESRATQTILLLVSTFVC---FYTLSTLLTICLNF------------LVNL-- --TWH-----------LVS------------------IHAIFSM---------------- ---C--FA-----------------------S-V--S---P--------------YL--- --------L-------------------------------MRH-------GSS------T ----S-IHCFAWV------------------------NYQKS------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >232-c ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MLN-- ----------NIMESR---------NMAI---GI---------GLSL------------- ---QSILGIL------------GNFALLFYYLTLYHKE---H-----TLKIRDM-ILIHV -------LTSNSLIIISKGFPQIM------------GAFGWNQLFNDVGCKLILYVQRL- ---SRNMSIITTCLLSVF-------QAITISPRNS-HWK-KFKIKST------KFMGLPI SLF---------WILIMLVNMLFPVYTSTKKNSKNKTQ-KRDSEFCHSL-GRDKIVDILY TAFCVFPEVVFS-----------LLIV-CSSTFMIAILHVHKKR----VQHILCTHTY-- ---PRRSPENRATQTILILVCTFLA---FYTLSSILQGYLAL------------SHDP-- --IWW-----------VMN------------------TTAIISM---------------- ---G--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------DFT------V ----S-RFCFT---------------------------WIKNIEKM-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >232.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MESR---------NMAI---GI---------GLSL------------- ---QSILGIL------------GNFSLLFYYLILYYKE---H-----TLKIRDM-ILVHV -------LTSNSLIIISKGFPQIM------------GAFGWNQLFNDVGCKLILYVQRL- ---SRNMSIITTCLLSVF-------QAITISPRNS-HWK-KFKVKST------KFMGLAI SLF---------WILFMLVNMLFPVYTSTKTNSKNKTQ-KRDSEFSHSL-GRDKIVDILY TTLCVFPEVVFS-----------LLIV-CSSTFMIAILHVHKKR----VQHILCTHTY-- ---PRKSPENRATQTILILVCTFLA---FYTLSSVLQG---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >232-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MESR---------NMAI---GI---------GLSL------------- ---QSILGIL------------GNFSLLFYYLILYYKE---H-----ILKIRDM-ILVHV -------LTSNSLIIISKGFPQIM------------GAFGWNQLFNDVGCKLILYVQRL- ---SRNMSIITTCLLSVF-------QAITISPRNS-RWK-KFKVKST------KFMGLPI SLF---------WILFMLVNMLFPVYTSTKTNSKNKTQ-KRDSEFCHSL-GRDKIVDILY TALCVFPEVVFS-----------LLIV-CSSTFMIAILHVHKKR----VQHVLCTHTY-- ---PRRSPENRATQTILILVCTFLA---FYTLSSVLQGYIAL------------SHDP-- --SWW-----------VMN------------------TTAIISM---------------- ---G--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MNR-------DFT------V ----F-RFCFT---------------------------WIRNIEKT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >232-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MESR---------NMAI---GI---------GLSL------------- ---QSILGIL------------GNFSLLFYYLILYYKE---H-----TLKIRDM-ILVHV -------LTSNSLIIISKGFPQIM------------GAFGWNQLFNDVGCKLILYVQRL- ---SRNMSIITTCLLSVF-------QAITISPRNS-HWK-KFKVKST------KFMGLPI SLF---------WILFMLVNMLFPVYTSTKTNSKNKTQ-KRDSEFCHSL-GRDKIVDILY TALCVFPEVVFS-----------LLIV-CSSTFMIAILHVHKKR----VQHILCTHTY-- ---PRRSPENRATQTILILVCTFLA---FYTLSSVLQGYIAL------------SHDP-- --SWW-----------VMN------------------TTAIISM---------------- ---G--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSR-------DFT------V ----F-RFCFT---------------------------WIRNIEKM-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >232-m -MLCD-----------------------------------------LEIGSTVILAH--- ---------------------TCP------------------------------------ ---------------------NLE----------NLLQYIVHK--CDYYHNLKEKTLN-- ----------DLMESR---------NMAI---GV---------GLSL------------- ---QSILGIL------------GNFSLLFYYLILYYKE---H-----TLKIRDM-ILVHV -------LTSNSLIIISKGFPQIM------------GAFGWNQLFNDVGCKLILYVQRL- ---SRNMSIITTCLLSVF-------QAITISPRNS-HWK-KFKVKST------KFMGLPI SLF---------WILFMLVNMLFPVYTSTKTNSKNKTQ-KRDSEFCHSL-GRDKIVDILY TALCVFPEVVFS-----------LLIV-CSSTFMIAILHVHKKR----VQHILCTHTY-- ---PRRSPENRATQTILILVCTFLA---FYTLSSVLQGYIAL------------SHDP-- --SWW-----------VMN------------------TTAIISM---------------- ---G--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSR-------DFT------V ----S-RFCFT---------------------------CIRNIEKT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >232.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------M-ILVHV -------LTSNSLIIISKGFPQIM------------GAFGWNQLFNDVGCKLILYVQRL- ---SRNMSIITTCLLSVF-------QAITISPRNS-HWK-KFKVKST------KFMGLAI SLF---------WILFMLVNMLFPVYTSTKTNSKNKTQ-KRDSEFCHSL-GRDKIVDILY TTLCVFPEVVFS-----------LLIV-CSSTFMIAILHVHKKR----VQHILCTHTY-- ---PRKSPENRATQTILILVCTFLA---FIHSLQFCKA-ILL------------FH---- ----------------------------------------MIPV---------------- ---G--G----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >229-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFG---------NLAI---GI---------VLSL------------- ---QSALGIL------------GNFSLLFYYLVLYNKE---H-----TLKIIDI-ILIHV -------FTSNSLIIFSKGLPEVL------------AVFGWNELFDDVGCKLIMFVRRV- ---SRSMSISMTCLLSVF-------QAITISTRNS-CWK-EFKEQTA------KFMGLFI SLC---------WILFMLVNMLFPVYTSTNRNSKNKTQ-KKDIEFCHSI-GRDKMVDIMY TAFCVFPEVLFS-----------LLIV-CSSTTMIVILYGHKKR----VQHILHTHAS-- ---PRMSAENRATQTILILVFTFLA---FYTLSSILQGYVAL------------SHDP-- --SWW-----------VMN------------------ITTIISM---------------- ---C--FP-----------------------A-I--G---P--------------FV--- ----------------------------------------MSR-------DFT------V ----S-RICFT---------------------------CIRNLKLP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >229-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFG---------NLAM---GI---------VLSL------------- ---QSALGIL------------GNFSLLFYYLVLYNKE---R-----TLKIIDI-ILIHV -------FTSNSLIIFSKGLPEVL------------AVFGWNDLFDDVGCKLIMYVRRV- ---SRSMSISMTCLLSVF-------QAITISTRNS-CWK-EFKEQTA------KFMGLFI SLC---------WILFMLVNMLFPVYTSTNRNSKNKTQ-KKDIEFCHSV-GRDKMVDIMY TAFCVFPEVLFS-----------LLIV-SSSTTMIVILYGHKKR----VQHILHTHAS-- ---PRTSAENRATQTILILVCTFLA---FYTLSSVLQGYVAL------------SHDP-- --SWW-----------VMN------------------ITTIISM---------------- ---G--FP-----------------------A-I--G---P--------------FV--- ----------------------------------------MSR-------DFT------V ----S-RFCFT---------------------------CIGNLKLP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >229-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFG---------NLAM---GI---------VLSL------------- ---QSALGIL------------GNFSLLFYYLVLYNKE---R-----TLKIIDI-ILIHV -------FTSNSLIIFSKGLPEVL------------AVFGWNDLFDDVGCKLIMYVRRV- ---SRSMSISMTCHLSVF-------QAITISTRNS-CWK-EFKEQTA------KFVGLFI SLC---------WILFMLVNMLFPVYTSTNRNSKNKTHTKKDIEFCHSV-GRDKMVDIMY TAFCVFPEVLFS-----------LLIV-SSSTTMIVILYGHKKR----VQHILHTHAS-- ---PRSSAENRATQTILILVCTFLA---FYTLSSVLQGYVAL------------SHDP-- --SWW-----------VMN------------------ITTIISM---------------- ---G--FP-----------------------A-I--G---P--------------FV--- ----------------------------------------MSR-------DFT------V ----S-RLCFT---------------------------CIRNLKLP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >229-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFG---------YVAM---GI---------VLSF------------- ---QSALGIL------------GNFSILFYYLILYNKK---R-----TLKIIDI-ILIHV -------FTSNSLIILSKGLPEVL------------AVFGWNELFDDVGCKLIMYVRRV- ---SRSMSISMTCLLSVF-------QAITISTTNS-CWK-EFKEQTA------KFMGLFI SLC---------WILFMLVNMLFPVYTSTNRNGKNKTQ-KKDIEFCHSV-GRDKMVDIMY TAFCVFPEVLFS-----------LLIV-CSSTSMIVILYGHKKR----VQHILHTHAS-- ---PRSSAENRATQTILILVFTFLA---FYTLSSILQGYVAL------------SHDP-- --SCW-----------VMN------------------ITTVISM---------------- ---C--FP-----------------------A-I--G---P--------------FV--- ----------------------------------------MSR-------DFT------V ----S-RFCFT---------------------------CIRNLKLP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >226-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLK---------TMIV---GI---------VISL------------- ---QTALGIL------------GNVTLLFYYLIIYYNE---H-----TLKKIDM-ILIHV -------FTSNFLTILSKGLPEVV------------RAFGWKQLFSDVGCKLTFYFQRL- ---ARSMSISTTCFLSVF-------QAITISPRNS-CLK-EYKTKTT------TFMGLSF SLC---------WILFILVNMLLPMYTATNRNKKNKTQ-KRDFEFCHSI-GRDKLVDIMY TAFCVFPEVLCS-----------LLIV-SSSAFMIFILYGHKKR----VQHTLHIHAS-- ---IRNSAEIRATHTILTLVCTFLA---FYTLSSILQGYIAL------------SNNP-- --SWW-----------VMN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------IV--- ----------------------------------------MSR-------DFV------I ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >226-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLR---------TMIV---GI---------VLSL------------- ---QTALGIL------------GNVSLLFYYLIIYYNE---H-----TMKKIDM-ILIHV -------FTSNFLTILSKGLPEVV------------KAFGWKQLFSDVGCKLT-YFQRL- ---ARSMSISTTCFLSVF-------QAITISPRNS-CLK-EYKTKTT------KFMGLFF SLC---------WILFILVNMLFPMYTATNRNKKNKTQ-KTDFEFCHSI-GRDKLVYIMY TAFCVFPEVLFS-----------LLIV-SSSAFMIFILYGHKKR----VQHTLHIHAS-- ---IRNSAENRATHNILTLVCTFLA---FYTLSSILQGYIAL------------SNNP-- --SWW-----------VMN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------IV--- ----------------------------------------MSP-------DFA------I ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >226-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLR---------TMIV---GI---------VLSL------------- ---QTALGIL------------GNVSLLFYYLIIYYNE---H-----TMKKIDM-ILIHV -------FTSNFLTILSKGLPEVV------------KAFGWKQLFSDVGCKLTNYFQRL- ---ARSMSISTTCFLSVF-------QAITISPRNS-CLK-EYKTKTT------KFMGLFF SLC---------WILFILVNMLFPIYTATNRNKKNKTQ-KRDFEFCHSI-GRDKLVDIMY TAFCVFPEVIFS-----------LLIV-SSSAFMIFILYGHKKR----VQHTLHIHAS-- ---IRNSAENRATHNILTLVCTFLA---FYTLSSILQGYIAL------------SNNP-- --SWW-----------VMN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------IV--- ----------------------------------------ISP-------DFA------I ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >226-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLR---------TMIV---GI---------VLSL------------- ---QTALGIL------------GNVSLLFYYLIIYYNE---H-----TMKKIDM-ILIHV -------FTSNFLTILSKGLPEVV------------KAFGWKQLFSDVGCKLTNYFQRL- ---ARSMSISTTCFLSVF-------QAITISPRNS-CLK-EYKTKTT------KFMGLFF SLC---------WILFILVNMLFPMYTATNRNKKNKTQ-KRDFEFCHSI-GHDKLVDIMY TAFCVFPEVLFS-----------LLIV-SSSAFMIFILYGHKKR----VQHTLHIHAS-- ---IRNSAENRATHNILTLVCTFLA---FYTLSSILQGYIAL------------SNNP-- --SWW-----------VMN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------IV--- ----------------------------------------MSP-------DFA------I ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >226-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLR---------TMVV---GI---------VLSL------------- ---QTALGIL------------GNVSLLFYYLIIYYNE---H-----TMKKIDM-ILIHV -------FTSNFLTILSKGLPEVV------------KAFGWKQLFSDVGCKLTYYFQRL- ---ARSMSISTTCFLSVF-------QAITISPRNS-CLK-EYKTKTT------KFMGLFF SLC---------WILFILVNMLFPMYTATNTNKKNKTQ-KRDFEFCHSI-GHDKLVDIMY TAFCVFPEVLFS-----------LLIV-SSSAFMIFILYGHKKR----VQHTLHIHAS-- ---IRNSAENRATHNILTLVCTFLA---FYTLSSILQGYIAL------------SNNP-- --SWW-----------VMN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------IV--- ----------------------------------------MSP-------DFA------I ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >228-c -MVQP-----------------------------------------RKVQTMLWLR---- ------------------------------------------------------------ ----------------------------------DMIVAII----------QRKQLLN-- ----------DRMDFR---------DMAV---GI---------VLSF------------- ---EILLGIL------------GNFSLLFYYLILYYKE---H-----TLRIIDM-ILIHV -------FTSNSLILLSKGPPEVM------------GAFGSKQLFNDVGCKLILYVQRI- ---ARCMSITTTCFLSVF-------QAITISPRNS-CWK-EFKVKTT------KFMGLSI SFY---------WVMFTLLNMLFPLYTASNSNRENRTQ-KSDSEFCHSG-GRDKIVDLLY AAFCVFPEVLFS-----------ILIV-VSSTFMIVILYRHKKR----VQHILHKHAS-- ---LRISAENRATQTILVLVFTFLV---FNTLSSILHGYIAL------------SHDP-- --NWW-----------VMN------------------ITAIIAL---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------DFT------A ----S-RCCFT---------------------------WIK------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >228-m -MAQP-----------------------------------------RKVQTMLWLR---- ------------------------------------------------------------ ----------------------------------DMIVAII----------QRKKLLN-- ----------DRMDFR---------DMAV---GI---------VLSF------------- ---EILLGIL------------GNFSLLFYYLILYYKE---H-----TLKIIDM-ILIHV -------FTSNALILLSKGPPEVM------------GAFGSKQLFNNVGCKLILYVQRI- ---ARCMSITTTCFLSVF-------QAITISPSNS-CWK-EFKVKTT------KFMGLSI SFY---------WVMFILLNMLFPLYTASNSNRENRTQ-KSDSEFCHSG-GRDKIVDLLY AAFCVFPEVLFS-----------LLIV-VSSTFMIVILYRHKKR----VQHILHKHAS-- ---LRISAENRATQTILVLVFTFLV---FNTLSSILHGYIAL------------SHDP-- --NWW-----------VMN------------------ITAIIAL---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------DFT------A ----S-RCCFT---------------------------WIKII----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >228-x -MAQP-----------------------------------------RKVQTMLWLR---- ------------------------------------------------------------ ----------------------------------DMIVAII----------QRKKLLN-- ----------DRMDFR---------DMAV---GI---------VLSF------------- ---EILLGIP------------GNFSLLFYYLILYYKE---H-----TLKTIDM-ILIHV -------FTSNSLILLSKGPPEVM------------GAFGSKQLFNDVGCKLILYVQRI- ---ARCMSITTTCFLSVF-------QAITISPRNS-CWK-EFKVKNT------KFMGLSI SFC---------WVMFMLLNMLFPLYTASNSNRENKTQ-KSDSEFYHSA-GRDKIVDLLY AAFCVFPEVLFS-----------LLIV-VSSTFMIVILYRHKKR----VQHILHKHAS-- ---LRISAENRATKTILVLVFTFLV---FNTLSSILHGYIAL------------SHDP-- --NWW-----------VMN------------------ITAIIAL---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------DFT------A ----F-RCCFT---------------------------WIKII----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >228-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFR---------DMAV---GI---------VLSV------------- ---EILLGIL------------GNFSLLFYYLILYYKE---H-----TLKIIDM-ILIHV -------FTSNSLILLSKGPPEVM------------GAFGSKQLFNDVGCKLILYVQRI- ---ARCMSITTTCLLSVF-------QAITISPRNS-CWK-EFKIKTT------KFMGLSI SLC---------WVMFMLLNMLFPLYTTTKSNRENKTQ-KSDSEFCHSG-GRDKIVDLLY AAFCVFPEVLFS-----------LLIV-VSSTFMIVILYRHKKR----VQHILYKHAS-- ---LRISAENRATQTILILVFTFLV---FNTLSSILHGYIAL------------SHDP-- --NWW-----------VMN------------------ITAIIAL---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------DFT------V ----S-RFCFT---------------------------WIKKNINIK------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >228-s -MTQP-----------------------------------------RKVQTMLWLR---- ------------------------------------------------------------ ----------------------------------DMIVAII----------QRKKLLN-- ----------DRMDFR---------DMAV---GI---------VLSF------------- ---EILLGIL------------GNLSLLFYYLILYLKE---H-----TLKTIDM-ILIHV -------FTSNSLILLSKGPPEVM------------GAFGSKQLFNDVGCKLILYVERI- ---ARCMSITTTCFLSVF-------QAITISPRNS-CWK-EFKVKTT------KFMGLSI SFY---------WVMLMLLNMLFPLYTASNSNRENKTQ-KSDSEFCHVV-GRDKIVDVLY --FVCFRKSYF--------------------------LY------------------S-- ---L-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >225-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MESR---------NMAI---GI---------ILLV------------- ---QSVLGIL------------GNIFLLLYYLILYYKE---C-----TLKIVDL-ILTHV -------FTSNFLIILSKGPAQIM------------AAFGWNQFFNDVGCKYILYIQRL- ---GRSMSISTTCLLSVF-------QAITISPRNS-YRK-EIKIKTT------KFIGFLI LLC---------WIVCLLVNTFFPLNASTKRKSKNKTQ-KRGFEFCLSQ-GRDKVVDTVY IAFWVFPEVLFS-----------VLIV-CSSTFMIVTLYGHKKR----VQGILSTHAS-- ---QQMSPENRATQKILALVCTFLA---FYTLSSILQGYIAL------------SHNP-- --SWW-----------VMN------------------ITSIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------YSI------F ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >225-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MESR---------NMAI---GI---------ILLV------------- ---QSVLGIL------------GNIFLLLYYLILYYKE---C-----TLKIVDL-ILTHV -------FTSNFLIILSKGPAQIM------------AAFGWNQFFNDVGCKHILYIQRL- ---GRSMSISTTCLLSVF-------QAITISPRNS-YWK-EIKIKTT------KLIGLLI LLC---------WIVCLLVNTFFPLNASTKRNSKNKTQ-KRGFEFCLSQ-GRDKVVDTVY IAFWVFPEVLFS-----------VLIV-CSSTFMIVTLYGHKKR----VQGILSTHAS-- ---QRMSPENRATQKILTLVCTFLA---FYTLSSILQGYIAL------------SHNP-- --SWW-----------VMN------------------ITSIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------YSI------F ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >225.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MESR---------NMAI---GI---------ILLV------------- ---QSILGIL------------GNIFLLLYYLILYYKE---C-----TLKIVDL-ILIHV -------FTSNFLIILSKGPAQIM------------AAFGWNQFFNDVGCKHILYIQRL- ---GRSMSISTTCLLSVF-------QAITISPRNS-YWK-EIKIKTT------KLIGLLI LLC---------WIVCLLVNTFFPLNASTKRNSKNKTQ-KRGFEFCLSQ-GRDKVVDTVY IAFWVFPEVLFS-----------VLIV-CSSTFMIVTLYGHKKR----VQGILSTHAS-- ---QRMSPENRATQKILTLVCTFLA---FYTLSSILQGYIAL------------SHNP-- --SWW-----------VMN------------------ITSIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------YSI------F ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >225.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------AAFGWNQFFNDVGCKHILYIQRL- ---GRSMSISTTCLLSVF-------QAITISPRNS-YWK-EIKIKTT------KLIGLLI LLC---------WIVCLLVNTFFPLNASTKRNSKNKTQ-KRGFEFCLSQ-GRDKVVDTVY IAFWVFPEVLFS-----------VLIV-CSSTFMIVTLYGHKKR----VQGILSTHAS-- ---QRMSPENRATQKILTLVCTFLA---FYTLSSILQGYIAL------------SHNP-- --SWW-----------VMN------------------ITSIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------YSI------F ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >225-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------AAFGWNQFFNDVGCKHILYIQRL- ---GRSMSISTTCLLSVF-------QAITISPRNS-YWK-EIKIKTT------KLIGLLI LLC---------WIVCLLVNTFFPLNASTKRNSKNKTQ-KRGFEFCLSQ-GRDKVVDTVY IAFWVFPEVLFS-----------VLIV-CSSTFMIVTLYGHKKR----VQGILSTHAS-- ---QRMSPENRATQKILTLVCTFLA---FYTLSSILQGYIAL------------SHNP-- --SWW-----------VMN------------------ITSIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------YSI------F ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >225-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------AAFGWNQFFNDVGCKHILYIQRL- ---GRSMSISTTCLLSVF-------QAITISPRNS-YWK-EIKIKTT------KLIGLLI LLC---------WIVCLLVNTFFPLNASTKRNSKNKTQ-KRGFEFCLSQ-GRDKVVDTVY IAFWVFPEVLFS-----------VLIV-CSSTFMIVTLYGHKKR----VQGILSTHAS-- ---QRMSPENRATQKILTLVGTFLA---FYTLSSILQGYIAL------------SHNP-- --SWW-----------VMN------------------ITSIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MSH-------YSI------F ----S-RFCFT------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >241-p ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MD-- ----------DKMESR---------NLAI---GI---------VLSL------------- ---QGVFGIL------------GNFSLLFHYLLLYYNE---G-----KLKTIDL-ILTHV -------FTANSLVIFSKGMLQIT------------GAFEWNQFFNGIGCNIILYILRL- ---GRSMSTYTTCLVSVF-------QAITISPWKS-CWK-DLIVKIR------RLMGFFI LIF---------WVIHMMMNMIFPIYSSTRRKTKNTTQ-KR-YGFCSSFLGHNNVRESLY TAFWVFPEVLLS-----------VVLV-ISSITMIVILYGHKKR----VQNIHSARVS-- ---PRNSPETRATQNILVLVCTFLT---FYTLTSILQGFITF------------SQNP-- --SWW-----------LVN------------------ITAIISM---------------- ---C--FP-----------------------T-V--G---P--------------FV--- ----------------------------------------MSR-------DII------L ----S-RSCLS---------------------------WMRNI----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >241.1-s -M---------------MIKSFALKQS-CY--------AADYSFAISHIHIQVW------ ---------------------EC------------------------------------- ---------------------SVK----------GLIEACLFVLFCFL-NDLNRKVMD-- ----------DKMGSR---------NLAI---GI---------VLSL------------- ---QGIFGIL------------GNFSLLFHYLLLYYNE---G-----KLKTIDL-ILTHV -------FTANSLIIFSKGMLQIT------------GAFGWNQFFNDIGCNLILYILRL- ---GRSMSIYTTCLVSVF-------QAITISPWKS-YWK-DLIVKIR------RLMGFFI SLC---------WILHMMVNMIFPMYPSTKGKTKNITQ-KRKYEFCSSFPGRDNIVESLY IAFWVFPEVLLS-----------VVLV-ISSITMIVILYGHKKM----VQHIHSSHVS-- ---PRNSPESRATQKILVLVCIFLT---FYTLSSILQGFITF------------SQNP-- --SWW-----------LIN------------------ITAIISM---------------- ---C--FP-----------------------T-V--G---P--------------FI--- ----------------------------------------MSH-------DII------L ----S-RFCLS------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >241.2-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MS-- ----------NHL----------------------------------------------- -----------------------------------------S-----KPRII-------- ------------------GMLQIT------------GAFGWNQFFNDIGCNLILYILRL- ---GRSMSIYTTCLVSVF-------QAITISPWKS-YWK-DLIVKIR------RLMGFFI SLC---------WILHMMVNMIFPMYPSTKGKTKNITQ-KRKYEFCSSFPGRDNIVESLY IAFWVFPEVLLS-----------VVLV-ISSITMIVILYGHKKM----VQHIHSSHVS-- ---PRNSPESRATQKILVLVCIFLT---FYTLSSILQGFITF------------SQNP-- --SWW-----------LIN------------------ITAIISM---------------- ---C--FP-----------------------T-V--G---P--------------FI--- ----------------------------------------MSH-------DII------L ----S-RFCLS------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >241-x ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MS-- ----------NHL----------------------------------------------- -----------------------------------------S-----KPRII-------- ------------------GMLQIT------------GAFGWNQFFNDIGCNLILYILRL- ---GRSMSIYTTCLVSVF-------QAITISPWKS-YWK-DLIVKIR------RLMGFFI SLC---------WILHMMVNMVFPMYPSTKGKTKNITQ-KRKYEFCSSFPGRDNIVESLY IAFWVFPEVLLS-----------VVLV-ISSITMIVILYGHKKM----VQHIHSSHVS-- ---PRNSPESRATQKILVLVCTFIT---FYTLSSILQGFITF------------SQNP-- --SWW-----------LVN------------------ITAIISM---------------- ---C--FP-----------------------T-V--G---P--------------FV--- ----------------------------------------MSH-------DII------L ----S-RFCLS------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >241-z ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MS-- ----------NHL----------------------------------------------- -----------------------------------------S-----KPRII-------- ------------------GMLQIT------------GAFGWNQFFNDIGCNLILYILRL- ---GRSMSIYTTCLVSVF-------QAITISPWKS-YWK-DLIVKIR------RLMGFFI SLC---------WILHMMVNTVFPMYPSTKGKTKNITQ-KRKYEFCSSFPGRDNIVESLY IAFWVFPEVLLS-----------VVLV-ISSITMIVILYGHKKM----VQHIHSSHVS-- ---PRNSPESRATQKILVLVCTFIT---FYTLSSILQGFITF------------SQNP-- --SWW-----------LVN------------------ITAIISM---------------- ---C--FP-----------------------T-V--G---P--------------FV--- ----------------------------------------MSH-------DII------L ----S-RFCLS------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >227-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLR---------TMTI---GI---------VISF------------- ---QTALGIL------------ENFFLLFYYLILYFNE---H-----TLKVIYR-IFIHM -------FLSNSLIIISIGIPGAF------------GAFGWNLVFNDFGCKLLLYTQRL- ---ARSMSISTTCLLSVF-------WVITISPRNY-CWK-EFKIKTT------KFVNLSI CLS---------WILLMLVNMLFPVYTTTKRNLENVTQ-MSDSQFCYSV-DHDKIVYLMY ISFCMFPEVLFS-----------VLLV-CSSIFMIVILYVHKKR----VQHTLHAHSS-- ---LRTSTENRAVQTILVLVCTFVV---FCTLSSILLGYIAL------------LDNP-- --SRW-----------LIN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------IGY-------DFT------V ----F-RFCFT---------------------------WTR------------------- -----------------------------------NIKIP-------------------- ------------------------------------------------------------ ------------- >227.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------MLVNMLFPVYTTTKRNLENVTQ-MSDSQFCYSV-DHDKIVYLLY IAFCMFPEVLFS-----------VLLV-CSSIFMIVILYVHKKR----VQHTLHAHSS-- ---LRTSTENRAVQTILVLVCTFVV---FCTLSSILLGYIAL------------LDNP-- --SRW-----------LMN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------IGC-------DFS------V ----F-RFCFT---------------------------WTR------------------- -----------------------------------NIKIP-------------------- ------------------------------------------------------------ ------------- >227.1-s -M---------------ILTYTYSKQE-NF--------SICFN---SEIQLLPRFK---- ------------------------------------------------------------ ----------------------------------------------------KKKMLK-- ----------ARMDLR---------TMAI---GI---------VLSL------------- ---QTALGIL------------GNFFLLFYYLILYFNE---H-----TLKVIYR-IFIHM -------FISNSLINISIGIPGAF------------EAFGWNLVFSDFGCKLLFYIQRL- ---ARSMSISTTCLLSVF-------WVITISPRNY-CWK-EFKIKTT------KFVNLSI CLS---------WILLMLVNMLFPVYTTTKRNLENVTQ-MSDSQFCYSV-DHDKIVYLLY IAFCMFPEVLFS-----------VLLV-CSSIFMIVILYVHKKR----VQHTLHAHSS-- ---LRTSTENRAVQTILVLVCTFVV---FCTLSSILLGYIAL------------LDNP-- --SRW-----------LMN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------IGC-------DFS------V ----F-RFCFT---------------------------WTR------------------- -----------------------------------NIKIP-------------------- ------------------------------------------------------------ ------------- >227-x ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MLK-- ----------ARMDLR---------TMAI---GI---------VLSL------------- ---QTALGIL------------GNFFLLFYYLILYFKE---H-----TLKVIYR-IFIHM -------FISNSLINISIGIPGAF------------EAFGWNLVFSDFGCKLLFYIQRL- ---ARSMSISTTCLLSVF-------WVITISPRNY-CWK-EFKIKTT------KFVNLSI CLS---------WILLMLVNMLFPVYTTTKRNLENVTQ-MSDSQFCYSV-DHDKIVYLLY IAFCMFPEVLFS-----------VLLV-CSSIFMIVILYVHKKR----VQHTLHAHSS-- ---LRTSTENRAVQTILVLVCTFVV---FCTLSSILLGYIAL------------LDNP-- --SRW-----------LMI------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------IGC-------DFT------V ----F-RFCFT---------------------------WTR------------------- -----------------------------------NIKIP-------------------- ------------------------------------------------------------ ------------- >227-z ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MLK-- ----------ARMDLR---------TMAI---GI---------VLSL------------- ---QTALGIL------------GNFFLLFYYLILYFNE---H-----TLKVIYR-IFIHM -------FISNSLINISIGIPGAF------------EAFGWNLVFSDFGCKLLFYIQRL- ---ARSMSISTTCLLSVF-------WVITISPRNY-CWK-EFKIKTT------KFVNLSI CLS---------WILLMLVNMLFPVYTTTKRNLENVTQ-MSDSQFCYSV-DHDKIVYLLY IAFCMFPEVLFS-----------VLLV-CSSIFMIVILYVHKKR----VQHTLHAHSS-- ---LRTSTENRAVQTILVLVCTFVV---FCTLSSILLGYIAL------------LDNP-- --SRW-----------LMI------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------IGC-------DFT------V ----F-RFCFT---------------------------WTR------------------- -----------------------------------NIKIP-------------------- ------------------------------------------------------------ ------------- >227-m ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MLK-- ----------ARMDLR---------TMAI---GI---------VLSL------------- ---QTALGIL------------GNFFLLFYYLILYFNK---H-----TLKVIYR-IFIHM -------FISNSLINISIGIPGAF------------EAFGWNLVFNDFGCKLLFYIQRL- ---ARSMSISTTCLLSVF-------WVITISPRNY-CWK-EFKIKTT------KFVNLSI CLS---------WILLMLVNMLFPVYTTTKRNLENVTQ-MSDSQFCYSV-DHDKIVYLLY IAFCMFPEVLLS-----------ILLV-CSSIFMIVILYVHKKR----VQHTLHAHSS-- ---LRTSTENRAVQTILVLVCTFVV---FCTLSSILLGYIAL------------LDNP-- --SRW-----------LMN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------IGC-------DFT------L ----F-RFCFT---------------------------WTR------------------- -----------------------------------NIKIP-------------------- ------------------------------------------------------------ ------------- >227-p ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MLK-- ----------ARMDLR---------TMTI---GI---------VLSL------------- ---QTALGVL------------GNFFLLFYYLILYFNE---H-----TLKVVYR-IFVHM -------FISNSLIIISIGITGAF------------GAFGWNLVFNDLGCKLLIYVQRL- ---ARSMSISTTCLLSVF-------WVITISPRNS-CWK-EFKIKTT------KFVNLSI CLC---------WILLMLVNMFFPVYTTIKRNLENMTQ-MSDSQFCYSV-DHDKIVHLLY IAFCMFPEVLFS-----------VLLV-CCSSFMTIILCKHKKR----VQHTLRAHSS-- ---LRTSTENRAVQTILVLVCTFLL---FCTLSSILLVCIAL------------LDNP-- --SGW-----------LVN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------IGC-------DFT------V ----F-RFCFT---------------------------WTR------------------- -----------------------------------NIKIP-------------------- ------------------------------------------------------------ ------------- >224-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLK---------DLII---GT---------VFLF------------- ---QSTVGIL------------GNFSLLTSYLFNYYSK---H-----KIKTTNL-ILTHL -------FTANFLILLSKGLLHTM------------ENFGLKEFINDFGCKFLLYIQRL- ---GRNMSISTTCFLSVF-------QAITISPRTS-FSM-SLKLKSP------NHIGLFT SLC---------WILYMALNLIFPVYMYNKENRANFTH-KNHLKYCSIV-VHDDFISSLY TAFIVLPEILFS-----------FLII-WSSSSMVVILYMHRQS----VQHIHSINIS-- ---SRTSPESRAIHRILALVFTFIG---FYALSSILQGCIAL------------VYNP-- --GWW-----------LVN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------FM--- ----------------------------------------MNH-------NST------R ----P-RLNFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >224-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLK---------DLII---GT---------VFLF------------- ---QSTVGIL------------GNFSLLTSYLFNYYSK---H-----TIKTTNL-ILTHL -------FTANFLILLSKGLLHTM------------QTFGLKEFINDFGCKFLLYIQRL- ---GRNMSISTTCFLSVF-------QAITISPRTS-FSM-SLKLKSP------NHIGLFT SLC---------WILYMTLNLIFPVYMYNKENRKNLTH-KNHWKHCSTV-VHDDFISSLY TAFIVLPEILFS-----------FIII-WSSSSMVVVLYMHRQS----IQHIHSINIG-- ---SRTSPESRATHRILALVSTFIG---FYALSSILQGYIAL------------VYNP-- --GWW-----------LVN------------------ITAIISI---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MNH-------DST------R ----P-RLSFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >224.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------QTFGLKGFINDFGCKFLLYIQRL- ---GRNMSISTTCFLSVF-------QAITISPRTS-FSM-SLKLKSP------NHIGLFT SLW---------WILYMALNLIFPVYMYNKENRKNLTH-KNHFKHCSTV-VHDDFISSLY TAFIVLPEILFS-----------FIII-WSSSSMVVVLYMHRQS----IQHIHSINIG-- ---SRTSPESRATHRILALVSTFIG---FYALSSILQGYIAL------------VYNP-- --GWW-----------LVN------------------ITAIISI---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MNH-------DST------R ----P-RLSFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >224.3-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLK---------DLII---GT---------VFLF------------- ---QSTVGIL------------GNFSLLTSYLFNYYSK---H-----TIKTTNL-ILTHL -------FTANFLILLSKGLLHTM------------QTFGLKGFINDFGCKFLLYIQRL- ---GRNMSISTTCFLSVF-------QAITISPRTS-FSM-SLKLKSP------NHIGLFT SLW---------WILYMALNLIFPVYMYNKENRKNLTH-KNHFKHCSTV-VHDDFISSLY TAFIVLPEILFS-----------FIII-WSSSSMVVVLYMHRQS----IQHIHSINIG-- ---SRTSPESRATHRILALVSTFIG---FYALSSILQGYIAL------------VYNP-- --GWW-----------LVN------------------ITAIISI---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MNH-------DST------R ----P-RLSFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >224-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------QTFGLKGFINDFGCKFLLYIQRL- ---GRNMSISTTCFLSVF-------QAITISPRTS-FSM-SLKLKSP------NHIGLFT SLC---------WILYMALNLIFPVYMYNKENRKNLTH-KNHFKHCSTV-VHDDFISSLY TAFIVLPEILFS-----------FIII-WSSSSMVVVLYMHRQS----IQHIHSINIG-- ---SRTSPESRATHRILALVSTFIG---FYALSSILQGYIAL------------VYNP-- --GWW-----------LVN------------------ITAIISI---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MNH-------DST------R ----P-RLSFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >224-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLK---------DLII---GT---------VFLF------------- ---QSTVGIL------------GNFSLLTSYLFNYYSK---H-----TIKTTNL-ILTHL -------FTANFLILLSKGLLHTV------------QTFGLKGFINDFGCKFLLYIQRL- ---GRNMSISTTCFLSVF-------QAITISPRTS-FSM-SLKLKSP------NHIGLFT SLC---------WILYMALNLIFPVYMYNKENRKNLTH-KNHFKHCSTV-VHDDFISSLY TAFIVLPEILFS-----------FIII-WSSSSMVVVLYMHRQS----IQHIHSINIG-- ---SRTSPESRATHRILALVSTFIG---FYALSSILQGYIAL------------VYNP-- --GWW-----------LVN------------------ITAIISI---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MNH-------DST------R ----P-RLSFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >224.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MVVVLYMHRQS----IQHIHSINIG-- ---SRTSPESRATHRILALVSTFIG---FYALSSILQGYIAL------------VYNP-- --GWW-----------LVN------------------ITAIISI---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MNH-------DST------R ----P-RLSFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >224.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLK---------DLII---GT---------VFLF------------- ---QSTVGIL------------GNFSLLTCYLFNYYIK---H-----TIKTTNL-ILTHL -------FTANFLLLLSKGLLHTM------------QTFGIKGFINDFCCKFLLYIQRL- ---GRNMSISTTCFLSVF-------QAITISPRNS-FSM-SLKLKAP------NHIGLFT SLF---------WILYMALNLIFPVYMYNKENIKNLTH-KNHLKYCSIV-VHDDFTSSLY TAFFVLPEILFS-----------FIII-WSSISMVIILYMHRQS----VQHIHSITTG-- ---YRTCPESIATHRILALVSTFIG---FYALSSILQGCIAL------------VYNP-- --DWW-----------LVN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MNH-------DST------M ----P-RLSFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >224.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDLK---------DLII------------------------------- ------------------------------------------------------------ ------------------GLLHTM------------QTFGIKGFINDFCCKFLLYIQRL- ---GRNMSISTTCFLSVF-------QAITISPRNS-FSM-SLKLKAP------NHIGLFT SLF---------WILYMALNLIFPVYMYNKENIKNLTH-KNHLKYCSIV-VHDDFTSSLY TAFFVLPEILFS-----------FIII-WSSISMVIILYMHRQS----VQHIHSITTG-- ---YRTCPESIATHRILALVSTFIG---FYALSSILQGCIAL------------VYNP-- --DWW-----------LVN------------------ITAIISM---------------- ---C--FP-----------------------T-L--G---P--------------FV--- ----------------------------------------MNH-------DST------M ----P-RLSFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >185-c ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MMK-- ----------HRIDFW---------NLTT---RI---------ILLS------------- ---QTTVGIL------------VNFSLMFYYLVLYYRK---C-----RLKPTDF-ILLHL -------LAANSLFIISSGVPHII------------ALWGLKQFLNGIVCELLFYIQGF- ---GRSVSIWTTCLLSVF-------QAMTISPRKS-CWK-DHKVKAL------THSGCSI SLM---------WVLHMLIHFIIFVYPFIKKDSKNVTK-LQDFGYCSIV-KKQNITEFLY AALVMFPEFFFS-----------VLIA-WSSGSMVVILLKHKQR----VQHIHRTHVS-- ---RRNSPESRATENILALVSTFLA---FYTLSSILRGCIAL------------LYNY-- --NWW-----------LMN------------------INHVTSL---------------- ---C--FP-----------------------S-F--G---P--------------CV--- --------F-------------------------------MRS-------YSL------M ----S-RFNLV---------------------------HLRKTNLSP------------- -----------------------------------NLVINM------------------- ------------------------------------------------------------ ------------- >185.1-s ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MMK-- ----------HRIDFW---------NLAT---RI---------ILLS------------- ---QTTVGIL------------VNFSLMFHYLVLYYRE---C-----RLKPTDF-ILLHL -------LAANSLFILSSGVPHII------------VLWGLKQFLNDIVCEFLFYIQGF- ---GRSVSIWTTCLLSVF-------QAMTISPRKS-CWK-DHKVKAI------MHNGCSI SLM---------WVLHMLMHFIIFVYPFIRMNSKNVTK-LQDFGYCSVV-KKQNITEFLY AALVMFPEFFFS-----------VLIA-WSSGSMIVILFKHKKR----VQHIHSTHVS-- ---RRNSPESIATQNILALVSTFLA---FYTLSSILRGCIAL------------LYNY-- --NWW-----------LMN------------------INHITSL---------------- ---C--FP-----------------------S-F--G---P--------------CV--- --------F-------------------------------MRS-------YSL------M ----S-RFNLA---------------------------HLRKTNLSP------------- -----------------------------------NLVINM------------------- ------------------------------------------------------------ ------------- >185-m ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MMK-- ----------HRIDFW---------NLAT---RI---------ILLS------------- ---QTTVGIL------------VNFSLMFHYLVLYYRE---C-----RLKPTDF-ILLHL -------LAANSLFILSSGVPHII------------AFWGLKQFLNDIVCEFLFYIQGF- ---GRSVSIWTTCLLSVF-------QAMTISPRKS-CWK-DHKVKAI------MHNGCSI SLM---------WVLHMLMHFIIFVYPFIKMNSKNVTK-LQDFGYCSVV-KKQNITEFLY AALVMFPEFFFS-----------VLIA-WSSGSMIVILFKHKKK----VQHIHSTHVS-- ---RRNSPESRATQNILALVSTFLA---FYTLSSILRGCIAL------------LYNY-- --NWW-----------LMN------------------INHITSL---------------- ---C--FP-----------------------S-F--G---P--------------CV--- --------F-------------------------------MRS-------YSL------M ----S-RFNLA---------------------------HLRKINLSP------------- -----------------------------------NLVINM------------------- ------------------------------------------------------------ ------------- >185-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MTISPRKS-CWK-DHKVKAI------MHNGCSI SLM---------WVLHMLMHFIIFVYPFIRMNSKNVTK-LQDFGYCSVV-KKQNITEFLY AALVMFPEFFFS-----------VLIA-WSSGSMIVILFKHKQR----VLHIHTTHVS-- ---RRNSPESRATQNILALVSTFLA---FYTLSSILRGCIAL------------LYNY-- --NWW-----------LMN------------------INHITSL---------------- ---C--FP-----------------------S-F--G---P--------------CV--- --------F-------------------------------MRS-------YSL------M ----S-RFNLA---------------------------HLRK------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >185.2-s ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MMK-- ----------HRIDFW---------NLAT---RI---------ILLS------------- ---QTTVGIL------------VNFSLMFHYLVLYYRE---C-----RLKPTDF-ILLHL -------LAANSLFILSSGVPHII------------VLWGLKQFLNDIVCEFLFYIQGF- ---GRSVSIWTTCLLSVF-------QAMTISPRKS-CWK-DHKVKAI------MHNGCSI SLM---------WVLHMLMHFIIFVYPFIRMNSKNVTK-LQDFGYCSVV-KKQNITEFLY AALVMFPEFFFS-----------VLIA-WSSGSMIVILFKHKKR----VQHIHSTHVS-- ---RRNSPESIATQNILALVSTFLA---FYTLSSILRGCIAL------------LYNY-- --NWW-----------LMN------------------INHITSL---------------- ---C--FS-----------------------V-F--W---A--------------MC--- --------F-------------------------------HEK-------L--------- ---------LP---------------------------HV-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >184-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ----------HRIAFW---------NLAA---RI---------TLLS------------- ---QTTVGIL------------VNFFLMFYYLVLYYRK---C-----RLKPTDF-ILLHL -------LAANSLFILSSGVPHII------------GLWGLKQFLNDIVCELLFYIQGF- ---GRSVSIWTTCLLSVF-------QAMTISPRKS-CWK-DHKVKAV------KHISSSI SLM---------WILHMLIHFFILVYPFIKMNSKNVTK-LQDFGYCSIV-KKENITEFLY AAFVMFPEFFFS-----------VLIA-WSSGSMIVILFKHKQR----VLHIHSTHVS-- ---RRNSPESRATQNILALVSTFLA---FYTLSSILRGYIIL------------LYNY-- --NWW-----------LMN------------------INHIISL---------------- ---C--FP-----------------------S-F--G---P--------------CV--- --------F-------------------------------IKS-------YSL------M ----S-RCNLA---------------------------HLRKNNNKP------------- --------------------------------------IS-------------------- ------------------------------------------------------------ ------------- >184.2-z ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MK-- ----------HRIDFW---------NLAA---RI---------TLLS------------- ---QTTVGIL------------VNFFLMFYYLVLYYRE---C-----RLKPTDF-ILLHL -------LAANSLFILSSGVPHII------------GLWGLKQFLNDIVCELLFYIQGF- ---GRSVSIWTTCLLSVF-------QAMTISPRKS-CWK-DHKVKAV------KHISCSI SLM---------WILHMLIHFFILVYPFIKMNSKNVTK-LQDFGYCSIV-KKENITEFLY AALVMFPEFFFS-----------VLIA-WSSGSMIVILFKHKQR----VLHIHSTHVS-- ---RRNSPESRATQNILALVSTFLA---FYTLSSILRGYIIL------------LYNY-- --NWW-----------LMN------------------INHITSL---------------- ---C--FP-----------------------S-F--G---P--------------CV--- --------F-------------------------------IKS-------YSL------M ----S-RCNLG---------------------------HLRKNNNKP------------- --------------------------------------IS-------------------- ------------------------------------------------------------ ------------- >184.1-z ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MMK-- ----------HRIDFW---------NLAT---RI---------ILLS------------- ---QTTVGIL------------VNFSLMFHYLVLYYRE---C-----RLKPTDF-ILLHL -------LAANSLFILSSGVPHII------------GLWGLKQFLNDIVCELLFYIQGF- ---GRSVSIWTTCLLSVF-------QAMTISPRKS-CWK-DHKVKAV------KHISCSI SLM---------WILHMLIHFFILVYPFIKMNSKNVTK-LQDFGYCSIV-KKENITEFLY AALVMFPEFFFS-----------VLIA-WSSGSMIVILFKHKQR----VLHIHSTHVS-- ---RRNSPESRATQNILALVSTFLA---FYTLSSILRGYIIL------------LYNY-- --NWW-----------LMN------------------INHITSL---------------- ---C--FP-----------------------S-F--G---P--------------CV--- --------F-------------------------------IKS-------YSL------M ----S-RCNLG---------------------------HLRKNNNKP------------- --------------------------------------IS-------------------- ------------------------------------------------------------ ------------- >240-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLAI---RI---------IFLS------------- ---QITIGIL------------GNVSLLFFYLVLYYRE---S-----ILKPTEL-ILMHL -------MAANIIIILSAGVPQTI------------TIWGLKQLLNDFGCKFLLYIHAI- ---GRSVSIFTTCLLSVF-------QAMTISPRKF-CGK-DHKVTIE------KYLGCFI SFL---------WVMYILVNLIFFVYTFIKKNSKNETR-KRNFGYCSTV-GSDNISDSLY AALVMCPEVVFS-----------VLIA-WSSGSMIVILYRHKKK----VQYIYRTRVS-- ---RRDYPESRATRNILAQVFTFLA---FYTLSSMLRGSIAL------------LPNQ-- --NLW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--G---P--------------FV--- --------L-------------------------------MSH-------YSF------V ----S-RFIFI---------------------------WLRKKICSF------------- ------------------------------------FKIITI------------------ ------------------------------------------------------------ ------------- >240.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MEFW---------NLAI---RI---------IFLS------------- ---QITIGIL------------GNVSLLFFYLFLYYKE---S-----ILKPTEL-ILMHL -------MAANIIIILSAGVPQTI------------TIWGLKQLLNDFGCKFLLYIHAI- ---GRSVSIFTTCLLSVF-------QAMTINPRKF-CGK-DHKVTIE------KYLGCFI SFL---------WVLYILVNLIFLVYTFIKKNSKNQTR-KRNFGYCSTV-GSDNISDSLY ATLVMCPEVFFS-----------VLIA-WSSGYMIAILYRHKKK----VQYIYSTRVS-- ---RRDYPESRATRNILAQMFTFLA---FYTLSSMLRGSIAL------------LPNQ-- --NLW-----------LMT------------------ISHLTSL---------------- ---C--FP-----------------------T-F--G---P--------------FV--- --------L-------------------------------MSH-------YSF------V ----S-RFIYV---------------------------WLRKRICSF------------- ------------------------------------FKL--------------------- ------------------------------------------------------------ ------------- >240-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLAI---RI---------IFLS------------- ---QITIGIL------------GNVSLLFFYLFLYYKE---S-----ILKPTEL-ILMHL -------MAANIIIILSAGVPQTI------------TIWGLKQLLNDFGCKFLLYIHAI- ---GRSVSIFTTCLLSVF-------QAMTISPRKF-CGK-YHKVTIE------KYLGCFI SFL---------WVLYILVNLIFLVYTFIKKNSKNETR-KRNFGYCSTV-GSDNISDSLY AALVMCPEVFFS-----------VLIA-WSSGSMIAILYRHKKK----VQYIYSTRVS-- ---RRDYPESRATRNILAQVFTFLA---FYTLSSMLRGSTAL------------LPNQ-- --NLW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--G---P--------------FV--- --------L-------------------------------MSH-------YSF------V ----S-RFIFV---------------------------WLRKRICSF------------L -----------------------------------NYKM--------------------- ------------------------------------------------------------ ------------- >240.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MEFW---------NLAI---RI---------IFLS------------- ---QITIGIL------------GNVSLLFFYLFLYYKE---S-----ILKPTEL-ILMHL -------MAANIIIILSAGVPQTI------------TIWGLKQLLNDFGCKFLLYIHAI- ---GRSVSIFTTCLLSVF-------QAMTINPRKF-CGK-DHKVTIE------KYLGCFI SFL---------WVLYILVNLIFLVYTFIKRIAK--IR-QEN------------------ VILDTAPQ---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >240.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MFHFL--------------------SL-GLVHL -------GKFN------------------------------------FPC-----VH--- ----------------IY-------Q---------------------------------- ------------------------------KNSKNQTR-KRNFGYCSTV-GSDNISDSLY ATLVMCPEVFFS-----------VLIA-WSSGYMIAILYRHKKK----VQYIYSTRVS-- ---RRDYPESRATRNILAQMFTFLA---FYTLSSMLRGSIAL------------LPNQ-- --NLW-----------LMT------------------ISHLTSL---------------- ---C--FP-----------------------T-F--G---P--------------FV--- --------L-------------------------------MSH-------YSF------V ----S-RFIYV---------------------------WLRKRICSF------------L -----------------------------------NYNI--------------------- ------------------------------------------------------------ ------------- >71-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLAI---RI---------IFLS------------- ---QTATGIL------------GNVFLIFYYLVLYYRE---C-----TLKPTDL-ILMNL -------LAANLVILLSIGVPQTM------------AIWGLKEFLNHLECELLLFIQGF- ---SRSMSICTICLLSVF-------QTLTISPKKF-CWK-YYKSKAA------KYIGSCT SLL---------WVLHVLINFIFFLYTFIKRNNTNVTR-TRDFGYCSHT-GSDDISDLIY AALVVCPEVFFS-----------VLTV-FTSVSMIVILYRHKKR----VQHIRSTHGS-- ---SRYSPESRATQNILTVVSTFLA---FCSLTTILRGCVAL------------FHGH-- --SWW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSI------V ----S-RLSLV---------------------------WLRKKKIS-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >71.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLAI---RI---------IFLL------------- ---QTVTGIL------------GNVFLIFYYLVLYYRE---C-----TLKPTDL-ILMNL -------MAANLVILLSIGVPQTM------------AIWGLKEFLNHLECELLLFIQGF- ---SRSMSICTICLLSVF-------QTLTISPKKF-CWK-YYKSKAA------KYIGSCT SLL---------WVLHMLINFIFVLYTFIKRNNTNVTR-TRDFGYCSLI-GSDDISDSLY AALVVCPEVFFS-----------VLTA-LASVSMIVILYRHKKR----VQHIRSTHGS-- ---SRYSPESRATQNILTVVSTFLA---FCTLTSILRGCVAL------------FHGH-- --SWW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSI------V ----S-RLSLV---------------------------WLRKKNIS-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >71.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLAI---RI---------IFLL------------- ---QTVTGIL------------GNVFLIFYYLVLYYRE---C-----TLKPTDL-ILMNL -------MAANLVILLSIGVPQTM------------AIWGLKEFLNHLECELLLFIQGF- ---SRSMSICTICLLSVF-------QTLTISPKKF-CWK-YYKSKAA------KYIGSCT SLL---------WVLHMLINFIFFLYTFIKRNNTNVTR-TRDFGYCSLI-GSDDISDSLY AALVVCPEVFFS-----------VLTA-LASVSMIVILYRHKKR----VQHIRSTHGS-- ---SRYSPESRATQNILTVVSTFLA---FCTLTSILRGCVAL------------FHGH-- --SWW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSI------V ----S-RLSLV---------------------------WLKKKNIS-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >71.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLAI---RI---------IFLL------------- ---QTVTGIL------------GNVFLIFYYLVLYYRE---C-----TLKPTDL-ILMNL -------MAANLVILLSIGVPQTM------------AIWGLKEFLNHLECELLLFIQGF- ---SRSMSICTICLLSVF-------QTLTISPKKF-CWK-YYKSKAA------KYIGSCT SLL---------WVLHMLINFIFVLYTFIKRNNTNVTR-TRDFGYCSLI-GSDDISDSLY AALVVCPEVFFS-----------VLTA-LASVSMIVILYRHKKR----VQHIRSTHGS-- ---SRYSPESRATQNILTVVSTFLA---FCTLTSILRGCVAL------------FHGH-- --SWW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSI------V ----S-RLSLV---------------------------WLRKK-ISH------------- -----------------------------------NSLIAQLFTHS-------------- ------------------------------------------------------------ ------------- >71-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLAI---RI---------IFLS------------- ---QTVTGTL------------GNVFLIFYYLVLYYRE---C-----TLKPTDL-ILMNL -------MAANLVILLSIGVPQTM------------AIWGLKEFLNHLECEILLFVQGF- ---SRSMSICTICLLSVF-------QTLTISPKKF-CWK-YYKSKAA------KYIGSCT SLL---------WVLHVLINFIFFLYTFIKRNNTNVTR-TRDFGYCSLI-GSDDISDSLY AALVVCPEVFFS-----------VLIA-FTSVSMIVILYRHKKS----VQHIRSTHGS-- ---SRYSPESRATQNILTVVSTFLA---FCTLTSILRGCVAL------------FHGH-- --SWW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSI------V ----S-RLSLV---------------------------WLRKK-ISH------------- -----------------------------------NSLIAQLFTHST------------- -L--------------IGQ----------------------------------------- ------------- >71.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLEI---RI---------IFLS------------- ---QTVTGTL------------GNVFLIFYYLVLYYRE---C-----TLKPTDL-ILMNL -------MAANLVILLSIGVPQTM------------AIWGLKEFLNHLECEILLFIQGF- ---SRSMSICTICLLSVF-------QTLTISPKKF-CWK-YYKSNAA------KYIGSCT SLL---------WVLHMLINFIFFLYTFIKRNNRNVTR-TRDFGYCSLI-GSDDISDLLY AALVVCPEVFFS-----------VLTA-FTSVSMIVILYRHKKR----VQHIRSTHGS-- ---SRYSPESRATQNILTVVSTFLA---FCSLTTILRGFVAL------------FHGH-- --SWW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSI------V ----S-RLSLV---------------------------WLRKK-ISH------------- -----------------------------------NSLIAQLFTHSS------------- -L--------------IGQ----------------------------------------- ------------- >71.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLEI---RI---------IFLS------------- ---QTVTGTL------------GNVFLIFYYLVLYYRE---C-----TLKPTDL-ILMNL -------MAANLVILLSIGVPQTM------------AIWGLKEFLNHLECEILLFIQGF- ---SRSMSICTICLLSVF-------QTLTISPKKF-CWK-YYKSNAA------KYIGSCT SLL---------WVLHMLINFIFFLYTFIKRNNRNVTR-TRDFGYCSLI-GSDDISDLLY AALVVCPEVFFS-----------VLTA-FTSVSMIVILYRHKKR----VQHIRSTHGS-- ---SRYSPESRATQNILTVVSTFLA---FCSLTTILRGFVAL------------FHGH-- --SWW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSI------V ----S-RLSLV---------------------------WLRKK-ISH------------- -----------------------------------NSLIAQLFTHS-------------- ------------------------------------------------------------ ------------- >71.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLAI---RI---------IFLL------------- ---QTVIGIL------------GNVFLIFYYLVLYYRE---C-----TLKPTDL-ILMNL -------MAANLVILLSIGVPQKM------------AIWGLKEFLNHLECEILLFVQGF- ---SRSMSICTICLLSVF-------QTLTISPKKF-CWK-YYKSNAA------KYIGSCT SLL---------WVLHVLINFIFFLYTFTKRNNTNVTR-TRDFGYCSLI-GSDDISDSLY AALVVCPEVFFS-----------VLTA-LASVSMIVILYRHKKS----VQHIRSTHGS-- ---SRYSPESRATQNILTVVSTFLA---FCSLTTILRGFVAL------------FHGH-- --SWW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSI------V ----S-RLSLV---------------------------WLRKKNIS-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >71.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------AIWGLKEFLNHLECEILLFVQGF- ---SRSMSICTICLLSVF-------QTLTISPKKF-CWK-YYKSNAA------KYIGSCT SLL---------WVLHVLINFIFFLYTFTKRNNTNVTR-TRDFGYCSLI-GSDDISDSLY AALVVCPEVFFS-----------VLTA-LASVSMIVILYRHKKS----VQHIRSTHGS-- ---SRYSPESRATQNILTVVSTFLA---FCSLTTILRGFVAL------------FHGH-- --SWW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSI------V ----S-RLSLV---------------------------WLRKKNIS-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >71.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDFW---------NLAI---RI---------IFLS------------- ---QTATGIL------------GNFFLIFYYLTLYYRE---C-----TLKPTDL-ILMNL -------MAANLVILLAIGVPQTM------------AIWGLKEFLNHLECDLLLFIQGF- ---GRSVSIYTICLLFVF-------QTVTISPKKF-GWK-YYKSKAV------KHIGSCT SLL---------WVLPMLINFILFLYTFIKRNNTNVTR-IRDFGYCSLT-GSDDISDLLY TVLVVCPEVFFS-----------MLTA-LASVSMIVILYRHKKR----VQHIHSTHGS-- ---SQYSPESRATQSILTVVSTFLA---FCTLTSILRGCVAL------------FHGH-- --SWW-----------LMN------------------INHLTSL---------------- ---C--FP-----------------------T-F--S---P--------------FV--- --------L-------------------------------MSH-------YSI------V ----S-RLSLV---------------------------CFRKK-KSH------------- -----------------------------------NSLIAQLFTHS-------------- ------------------------------------------------------------ ------------- >71.2-p -M---------------LL------------------------------TLFFWSYN--- ---------------------FCGH----------------------------PG----- ----------------------------------------------------KEIVLN-- ----------DIMDLW---------NMAI---RI---------IFLL------------- ---QTTTGIF------------GNSSLILYYLICYYKK---Y-----TLKPTDF-ILFHI -------MTANALIILSLGVPQTL------------SVWGLKEFLNNFGCDLLLYIQGF- ---GRRVSICMTCLLSIF-------QTITINPRKL-CWK-YHKVVAS------KVIGCSI SLF---------WVLHMLINFIFFVYTSIKRNRKNVTR-IRDLGYCFLI-GSDDISDFLY TALVVCPEVIFS-----------VFIA-WSSGSMIVILYRHKQR----VQYIHSSHRS-- ---CRCSTESRATQNILALLSTFLT---CYTLSSILRGCIAF------------LHNH-- --NWW-----------LMN------------------INHFISL---------------- ---C--FP-----------------------S-F--A---P--------------FV--- --------L-------------------------------ISH-------YSM------V ----S-RFSLY---------------------------WLRKKK---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >68-c -M---------------PLNGEG-K------------------------TVSIWPYNISL NDEYSK------------------------------------------------------ ---------------------IMK----------KMGVAEI-----------QENQTQ-- ----------SKMDFW---------NMGI---KI---------LFLS------------- ---QITTGIL------------GNFSLIIYYVV-NYIE---H-----TLKPTDL-ILMHL -------MTSNALMVLSTGVFHTM------------AAFGLTHLLNDLGCRLILYIQRV- ---GRSISIGTTCLLSIF-------QAITINDRVS-CYK-GQKIKSA------KYIGYSI SLL---------WVLHMLINFILFVDIFIKRNRNNMTR-DHDFKYYSIV-ERNEFSDSLY VALVVCPEIFSS-----------VLIT-CSSGSMIGILYRHKQR----VQHIRSFHVS-- ---TRNSPEWRATQNILVLVSTFLA---FYTLSSVLQGCIAL------------LNNP-- --NWW-----------LVN------------------ITRLTFL---------------- ---C--FP-----------------------T-F--A---P--------------CV--- --------L-------------------------------MSH-------YSF------M ----P-RFSLV---------------------------WTWNKTS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >68.1-s ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------MDVAII-----------KENQTQ-- ----------SKMDFW---------NMGI---KI---------LFLS------------- ---QTTTGIL------------GNFSLIIYYVV-NYIV---H-----TLKPTDL-ILMHL -------MTSNALMVLSTGVLHTM------------AVFGLAHLLNDLGCRLILYIQRV- ---GRSTSIGTICLLSIF-------QAITISHRVS-CYK-GQKIKSS------KYIGYSI SLL---------WVLHMFLNFILYVDIFIKSNRNNMTR-DRDFKYYSIV-ERNEFSDSLY VALVVCPEIFSS-----------VLIT-CSSGSMIGILYRHKQR----VQHIRSFHVS-- ---SRNSPEWRATQNILVLVSTFLA---FYTLSSVLQGCIAL------------LNNP-- --NWW-----------LVN------------------ITRLTSL---------------- ---C--FP-----------------------T-F--A---P--------------CV--- --------L-------------------------------MSH-------YSF------I ----S-RFSLV---------------------------WTWNKTS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >68.2-s ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------MGVAII-----------KENQTQ-- ----------SKMDFW---------NMGI---KI---------LFLS------------- ---QTTTGIL------------GNFSLIIYYVV-NYIV---H-----TLKPTDL-ILMHL -------MTSNALTVLSTGVLHTM------------AAFGLAHLLNDLGCRLILYIQRV- ---GRSTSIGTICLLSIF-------QAITISHRVS-CYK-GQKIKSS------KYIGYSI SLL---------WVLHMILNFILCVDIFIKSNRNNMTR-DRDFKYYSIV-ERNEFSDSLY VALVVCPEIFSS-----------VLIT-CSSGSMIGILYRHKQR----VQHIRSFHVS-- ---SRNSPEWRATQNILVLVSTFLA---FYTLSSVLQGCIAL------------LNNP-- --NWW-----------LVN------------------ITRLTSL---------------- ---C--FP-----------------------T-F--A---P--------------CV--- --------L-------------------------------MSH-------YSF------I ----S-RFSLV---------------------------WTWNKTS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >68-m ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------MGVAII-----------KENQTQ-- ----------SKMDFW---------NMGI---KI---------LFLS------------- ---QTTTGIL------------GNFSLIIYYVV-NYIV---H-----TLKPTDL-ILMHL -------MTSNALMVLSTGVLHTM------------AAFGLAHLLNDLGCRLILYIQRV- ---GRSTSIGTICLLSIF-------QAITISHRVS-CYK-GQKIKSS------KYIGYSI SLL---------WVLHMFLNFILFVDIFIKRNRNNMTS-DRDFKYYSIV-ERNEFSDSLY VALVVCPEIFSS-----------VLIT-CSSGSMIGILYRHKQR----VQHIRSFHVS-- ---SRNSPEWRATQNILVLVSTFLA---FYTLSSVLQGCIAL------------LNNP-- --NWW-----------LVN------------------ITRLTSL---------------- ---C--FP-----------------------T-F--A---P--------------CV--- --------L-------------------------------MSH-------YSF------M ----P-RFSLV---------------------------WTWNKTS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >68-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------AAFGLAHLLNDLGCRLILYIHRV- ---GRSTSIGTICLLSIF-------QAITISHRVS-CYK-GQKVKSS------KYIGYSI SLL---------WVLHMFLNFILFVDIFIKRNRNNMTR-DSDFKYYSIV-ERNEFSDSLY VALVVCPEIFSS-----------VLIT-CSSGSMIGILYRHKQR----VQHIRSFHVS-- ---SRNSPEWRATQNILVLVSTFLA---FYTLSSVLQGCIAL------------LNNP-- --NWW-----------LVN------------------ITRLTSL---------------- ---C--FP-----------------------T-F--A---P--------------CV--- --------L-------------------------------MSH-------YSL------M ----P-RFSLV---------------------------WTWNKTS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >68-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MHL -------MTSNALMVLSTGVLHTM------------AAFGLAHLLNDLGCRLILYIHRV- ---GRSTSIGTICLLSIF-------QAITISHRVS-CYK-GQKVKSS------KYIGYSI SLL---------WVLHMFLNFILFVDIFIKRNRNNMTR-DRDFKYYSIV-ERNEFSDSLY VALVVCPEIFSS-----------VLIT-CSSGSMIGILYRHKQR----VQHIRSFHVS-- ---SRNSPEWRATQNILVLVSTFLA----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >68-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------AAFGLTHLLNDLGCRLILYIQRV- ---GRSTSIGTTCLLSIF-------QAITISHRES-CYT-CQIVKSS------KYIGYSI SLL---------WVLHMFINFILFVDIFIKSNRNNLTR-NRDFKYYSIV-ERNELSDSLY AALVVCPEIFSS-----------VLIT-CSSGSMIGILYKHKQR----VQHIRSFHVS-- ---SRNSPEWRATQNILVLVSTFLA---FYTLSSILQGCIAL------------LNNP-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >69-s -M---------------CTRTPC-K------------------------------YN-SR CDRFSKNGHSFSSSYHLQGVLQCQC----------------------------MGT---- ---------------------GRQ----------KMGVAII-----------KENQAQ-- ----------SKMDFR---------NLAI---KI---------IFLS------------- ---QTTIGIL------------GNFSLIIYYVV-YSID---H-----TLKPTDL-ILMHL -------VTSNALMVLSTGVPHTM------------AAFGLTHLLNDLGCRLILYIQRV- ---GRSISIGSTCLLSIF-------QAIIISHRES-CYK-GQKVKSA------KYVGYSL SLL---------WVLHIFINFILFVDIFIKRNRNNMTR-DRDFKYCYIV-GQNEFSDLLY VALVVCPEILSS-----------VLIT-YSSGSMIGILYRHKQR----VQHIRSFHVS-- ---SRSSPEWRATQNILVLVSTFLG---FYTLSSILQGCIAL------------LNNP-- --NWW-----------LLN------------------INRLTSL---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSF------M ----P-KLSLT---------------------------WIRNKTS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >69.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------AAFGLTHLLNDLGCRLILYIQRV- ---GRSISIGSTCLLSIF-------QAIIISHRES-CYK-GQKVKSA------KYVGYSL SLL---------WVLHIFINFILFVDIFIKRNRNNMTR-DRDFKYCYIV-GQNEFSDLLY VALVVCPEILSS-----------VLIT-YSSGSMIGILYRHKQR----VQHIRSFHVS-- ---SRNSPEWRATQNILVLVSTFLG---FYTLSSILQGCIAL------------QNNP-- --NWW-----------LLN------------------INRLTSM---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSF------M ----P-KLSLT---------------------------WIRNKTS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >69.2-m ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------MGVATI-----------KENQAQ-- ----------SKMDFR---------NLAI---KI---------IFLS------------- ---QTTIGIL------------GNFSLIIYYVV-YYIV---Y-----TLKPTDL-ILMHL -------VTSNALMVLSTGVPHTM------------AAFGLTHLLNDLGCRLILYIQRV- ---GRSISIGSTCLLSIF-------QAIIISHRES-CYK-GQKVKSA------KYVGYSL SLL---------WVLHIFINFILFVDIFIKRNRNNMTR-DRDFKYCYIV-GQNEFSDLLY VALVVCPEILSS-----------VLIT-YSSGSMIGILYRHKQR----VQHIRSFHVS-- ---SRNSPEWRATQNILVLVSTFLG---FYTLSSILQGCIAL------------QNNP-- --NWW-----------LLN------------------INRLTSM---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSF------M ----P-KLSLT---------------------------WIRNKTS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >69-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MHL -------VTSNALMVLSTGVPHTM------------AAFGLTHLLNDLGCRLILYIQRV- ---GRSISIGSTCLLSIF-------QAIIISHWKS-CYK-GQKVKSA------KYVGYSL SLL---------WVLHIFINFILFVDIFIKRNRDNMTR-DRDFKYCYIV-GQNEFSDLLY VALVVCPEILFS-----------VLIT-YSSGSMIGILYRHKQR----VQHIRSLHVS-- ---SRNSPEWRATQNILVLVSTFLG---FYTLSSILQGCIAL------------LNNP-- --NWW-----------LLN------------------INRLTSM---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSF------M ----P-KLSLT---------------------------WIRNKTS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >69-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------AAFGLTHLLNDLGCRLILYIQRV- ---GRSISIGSTCLLSIF-------QAIIISHRES-CYK-GQKVKSA------KYVGYSL SLL---------WVLHIFINFILFVDIFIKRNRDNMTR-DRDFKYCYIV-GQNEFSDLLY VALVVCPEILFS-----------VLIT-YSSGSMIGILYRHKQR----VQHIRSLHVS-- ---SRNSPEWRATQNILVLVSTFLG---FYTLSSILQGCIAL------------LNNP-- --NWW-----------LLN------------------INRLTSM---------------- ---C--FP-----------------------T-F--A---P--------------FV--- --------L-------------------------------MSH-------YSF------M ----P-KLSLT---------------------------WIRNKTS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >67.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGFR---------NLAI---KI---------LFLS------------- ---QTTTGIL------------GNFSLLIYYLV-YYIQ---H-----ALKPTDL-ILMHL -------MASNALIVLSAGIPHTL------------AAFELKQFLNDFGCRLILYIQSV- ---GRSVSISTTCLLSVF-------QAITISHRES-CCN-DQKVNAA------KYIGCSI FSL---------WVLFIIIHFIFFVYILVKRNSKNMTR-IRNFEYCSFG-GGDDINASLY TALAVCPEIFFS-----------LLIA-WSSVFMIVILYRHKQR----FQHIHSNTVY-- ---SRISPESRATQKILVLVCTFLA---FFTISSVLKGCISH------------LHNL-- --NWW-----------FVN------------------ITRLTSL---------------- ---C--FP-----------------------S-F--G---P--------------FV--- --------L-------------------------------MSH-------CTF------M ----P-RLSLI---------------------------WIRNKIS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >67-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGFR---------NLAI---KI---------LFLS------------- ---QITTGIL------------GNFSLLIYYLV-YYIQ---H-----ALKPTDL-ILMHL -------MASNALIVLFTGMPHTL------------AAFEIKQFLNDLGCRLILYIQSV- ---GRSVSISTTCLLSVF-------QAITISHRKS-CCK-DQKVNAA------KFIGCCI FSL---------WVLFVIIHFIFFAYILVKRNSKNMTR-NRNFEYCSIR-GGDDINASLY TALVVCPEIFFS-----------VLIA-WSSVSMIVILYRHKQR----FQHIHSNTIY-- ---SRISPESRATQKILVLVCTFLA---FYTISSVLQGCIAL------------LHNH-- --NWW-----------LVN------------------ITRLTSL---------------- ---C--FP-----------------------S-F--G---P--------------FV--- --------L-------------------------------MNH-------CTF------V ----P-RLSLI---------------------------WMWNKIT--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >67.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGFR---------NLAI---KI---------LFLS------------- ---QITSGIL------------GNFSLLIYYLV-YYIQ---H-----ALKPTDL-ILMHL -------MASNALIVLFTGMPHTL------------AAFEIKQFLNDLGCRLILYIQSV- ---GRSVSVSTTCLLSVF-------QAITISHRKS-CFK-DQKVNAA------KYIGCCI FSL---------WVLFVIIHFIFFAYILVKRNSKNMTR-NRNFEYCSIR-GGDDINASLY TALVVCPEIFFS-----------VLIA-WSSVSMIVILYRHKQT----FQHIHSNTIY-- ---SRISPESRATQKILVLVCTFLA---FYTISSVLQGCIAL------------LHNH-- --NWW-----------LVN------------------ITRLTSL---------------- ---C--FP-----------------------S-F--G---P--------------FV--- --------L-------------------------------MNH-------CTF------V ----P-RLSLI---------------------------WMWNKIT--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >67.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------MPHTL------------AAFEIKQFLNDLGCRLILYIQSV- ---GRSVSVSTTCLLSVF-------QAITISHRKS-CFK-DQKVNAA------KYIGCCI FSL---------WVLFVIIHFIFFAYILVKRNSKNMTR-NRNFEYCSIR-GGDDINASLY TALVVCPEIFFS-----------VLIA-WSSVSMIVILYRHKQT----FQHIHSNTIY-- ---SRISPESRATQKILVLVCTFLA---FYTISSVLQGCIAL------------LHNH-- --NWW-----------LVN------------------ITRLTSL---------------- ---C--FP-----------------------S-F--G---P--------------FV--- --------L-------------------------------MNH-------CTF------V ----P-RLSLI---------------------------WMWNKIT--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >67-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGFR---------NLAI---KI---------LFLS------------- ---QITTGIL------------GNFSLLIYYLV-YYIQ---H-----ALKPTDL-ILMQL -------MASNALIVLSRGMPHTL------------AAFELKQFLNDLGCRLILYIQSV- ---GQSVSISTTCLLSVF-------QAITISRRKS-CCK-DQKVNAA------KYIWCCI FSL---------WVLFIIIHFIFFAYILVKRNSKNMTR-NRNFEYCSIR----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >67-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGFR---------NLAI---KI---------LFLS------------- ---QITTGIL------------GNFSLLIYYLV-YYIQ---H-----ALKPTDL-ILMQL -------MASNALIVLSRGMPHTL------------AAFELKQFLNDLGCRLILYIQSV- ---GQSVSISTTCLLSVF-------QAITISRRKS-CCK-DQKVNAA------KYIWCCI FSL---------WVLFIIIHFIFFAYILVKRNSKNMTR-NRNFEYCSI------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >67.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MEFW---------NMII---KI---------ILLL------------- ---QITIGIL------------GNVSLLIYYIF-DYIE---H-----TLKTTDW-ILMHL -------MGSNALIVLSKGVPHTL------------AAFGMKQFLNDVGCTLVLYIQRV- ---GRSVSISTTCLLSIF-------QAITISHRKS-CCK-DQKMKAA------EYISCST SLL---------WVLSMIINFIFFAYIIVKRNSKNMTR-NRDFEYCSTA-GRDEINDLIY AALVTCPEIFFS-----------VLIA-WSSSSMIVILYKHKQR----VKHIHSHHVF-- ---RRNSPESIATQNILVLVSTFLA---FYTVSSVLQGCLAL------------LYNH-- --TWW-----------LVN------------------ITRITSL---------------- ---C--FP-----------------------S-F--G---P--------------LV--- --------L-------------------------------TSH-------YSI------L ----P-RHSLV---------------------------MIRNKV---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >66-c ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MPN-- ----------HKMDLG---------NLAI---KI---------IFLL------------- ---QTTVGIL------------GNFYLLIQHLV-YYAE---Y-----TLKHTDL-ILMHL -------WGANALIVLSTGVLYTM------------AAFGLKQFLNDFGCRLSLYIQRL- ---GRSVSIGTTCFLSVF-------QAITISHRES-CCK-DQKAKVA------KYIGFSI FLL---------WVLSMFIHLIFFLEIFLKRNSKNMTR-KLDFEYCSYV-NHFEINHLVY AALVMFPEIFFS-----------AVIA-WCSGSMTVILYRHKKR----VQHIYSSHVS-- ---RRNSPESRAIQTILSLVFFFLA---FYTLSSILRGYIAL------------LHNP-- --SWG-----------VVM------------------VNRLTSL---------------- ---C--FP-----------------------S-F--G---P--------------II--- --------F-------------------------------INN-------YSV------M ----P-RLSLV---------------------------WIRNTNP--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >66-s ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MPN-- ----------HKIDLG---------NLSI---KI---------IFLL------------- ---QTTVGIL------------GNFYLLILHLV-YYAE---Y-----TLKHTAL-ILMHL -------WGANALIVLSTGVPYTM------------AAFGLKQFLNDFGCRLSLYIQRL- ---GRSVSIGTTCFLSVF-------QAITISHRES-CCK-DQKAKVA------KYIGFSI FLL---------WVLSIFIHFIFFLEIFLKRNSKNMTR-KLDFEYCSYV-NHFEINHSVY AALVMCPEIFFS-----------VVIA-WSSGSMTVILYRHKKR----VQHIHSSQVS-- ---RRNSPESRAIQTILSLVFFFLA---FYTLSSILRGYIAL------------VHNP-- --SWC-----------LVM------------------VNRLTSL---------------- ---C--FP-----------------------S-F--G---P--------------FV--- --------L-------------------------------INN-------YSV------R ----P-RLSLI---------------------------WMRNINP--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >66-m ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MPN-- ----------HKIDLG---------NLSI---KI---------IFLL------------- ---QTTVGIL------------GNFYLLILHLV-YYAE---Y-----TLKHTAL-ILMHL -------WGANALIVLSTGVPYTM------------AAFGLKQFLNDFGCRLSLYIQRL- ---GRSVSIGTTCFLSVF-------QAITISHRES-CCK-DQKAKVA------KYIGFSI FLL---------WVLSIFIHFIFFLEIFLKRNSKNMTR-KLDFEYCSYV-NHFEINHSVY AALVMCPEIFFS-----------VVIA-WSSGSMTVILYRHKKR----VQHIHSSQVS-- ---RRNSPESRAIQTILSLVFFFLA---FYTLSSILRGYIAL------------VHNP-- --SWC-----------LVM------------------VNRLTSL---------------- ---C--FP-----------------------S-F--G---P--------------FV--- --------L-------------------------------INN-------YSV------R ----P-RLSLV---------------------------WMRNINP--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >66-x ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MPN-- ----------HKIDLG---------NLSI---KI---------IFLL------------- ---QTTVGIL------------GNFYLLILHLV-YYAE---Y-----TLKHTAL-ILMHL -------WGANALIVLSTGVPYTM------------AAFGLKQFLNDFGCRLSLYIQRL- ---GRSVSIGTTCFLSVF-------QAITISHRES-CCK-DQKAKVA------KYIGFSI FLL---------WVLSIFIHFIFFLEIFLKRNSKNMTR-KLDFEYCSYV-NHFEINHSVY AALVMCPEIFFS-----------VVIA-WSSGSMTVILYRHKKR----VQHIHSSQVS-- ---RRNSPESRAIQTILSLVFFFLA---FYTLSSILRGYIAL------------VHNP-- --SWC-----------LVM------------------VNRLTSL---------------- ---C--FP-----------------------S-F--G---P--------------FV--- --------L-------------------------------INN-------YSV------R ----P-RLSLV---------------------------WMRNNNP--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >66-p ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MIN-- ----------HKMDLG---------NLAI---KI---------MFLL------------- ---QTTAGIL------------GNFSLLIQHLV-YYAE---Y-----TLKHTDM-ILMNL -------WGANALIVLSVGVPYTM------------AAFGLKQFLNDFGCRLSLYIQRV- ---GRSVSIGTTCFLSVF-------QAINISHRES-CCK-DQKAKVA------KYIGYSI SLL---------WVLSMFIHFIFFVEIFLKRNSKNMTR-KLDFEYCSYV-NHFEINGSVY AALVMCPEIFFS-----------VVIV-WSSGSTTVILYRHKKR----VQHIHSSQVS-- ---RRHSAESRAIKTILSLVFSFLA---FYSLSSILRGYIAL------------LHNP-- --SWG-----------LVM------------------VNRLSSL---------------- ---C--FP-----------------------S-F--G---P--------------FV--- --------L-------------------------------INH-------YPV------M ----P-RLRLV---------------------------WMRNTNP--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >231-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------MYTERV- ---GRSVSIGTICLLSVF-------QAITISPSDS-CLN-GLKVKVP------KYISLSI FLC---------WVLFLGLNMISPMYVYIKWNSNNVTY-KRTSNYCFSL-GHDEFSGPMI TTFFVFPEVLFA-----------ILIV-WSGSLMVIILYRHKQR----VQHIHCTYAP-- ---TRTSHESRATKNILVLVSLFIG---FYSLSSILHTCVAL------------FCGA-- --GWW-----------LIN------------------ITVIIHL---------------- ---C--FP-----------------------T-L--G---P--------------FI--- ----------------------------------------VTP-------DTA------L ----P-RFSLS---------------------------WIRNTERT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >231.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML------------- ---TSSV----------------------------------------------------- --------------LEKRIVLQTM------------QTFGMELFFNVFVCKFPMYTERV- ---GRSVSIGTICLLSVF-------QAITISPSDS-CLN-GLKVKVP------KYISLSI FLC---------WVLFLGLNMISPMYVYIKWNSNNVTY-KITSNYCFSL-GHDEFTGPMI TTFFVFPEVLFA-----------ILIV-CSGSLMVVILYRHKQR----VQHIHSTYAP-- ---TRTSHESRATKNILVLVSIFIG---FYSLSSILHTCLAL------------FCGA-- --GWW-----------MIN------------------ITVIIHL---------------- ---C--FP-----------------------T-L--G---P--------------FI--- ----------------------------------------VTH-------DSA------L ----P-RFSLS---------------------------WIRNTGRT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >231.2-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML------------- ---TSSV----------------------------------------------------- --------------LEKRIVLQTM------------QTFGMELFFNVFVCKFPMYTERV- ---GRSVSIGTICLLSVF-------QAITISPSDS-CLN-GLKVKVP------KYISLSI FLC---------WVLFLWLNMISPMYVYIKWNSNNVTY-KRTSNYCFSL-GHDEFTGPMI TTFFVFPEVLCA-----------ILIV-CSGSLMVIILYRHKQR----VQHIHSTYAP-- ---TRTSHESRATKNILVLVSLFIG---FYSLSSILHTCVAL------------FCGA-- --GWW-----------MIN------------------ITVIIHL---------------- ---C--FP-----------------------T-L--G---P--------------FI--- ----------------------------------------VTH-------DTA------L ----P-RFSLS---------------------------WIRNTGRT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >231.1-s ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MVN-- ----------DKMDSK---------NLAI---FV---------ILIL------------- ---QCSVGIL------------KNICLLSYYLMLHYNK---H-----TLKRIDL-IFMNM -------FIANFFIIFSRIVLQTM------------QTFGMELFFNVFVCKFPMYTERV- ---GRSVSIGTICLLSVF-------QAITISPSDS-CLN-GLKVKVP------KYISLSI FLC---------WVLFLGLNMISPMYVYIKWNSNNVTY-KITSNYCFSL-GHDEFTGPMI TTFFVFPEVLFA-----------ILIV-CSGSLMVVILYRHKQR----VQHIHSTYAP-- ---TRTSHESRATKNILVLVSIFIG---FYSLSSILHTCLAL------------FCGA-- --GWW-----------MIN------------------ITVIIHL---------------- ---C--FP-----------------------T-L--G---P--------------FI--- ----------------------------------------VTH-------DSA------L ----P-RFSLS---------------------------WIRNTGRT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >231.2-s ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MVN-- ----------DKMDSK---------NLAI---FV---------ILIL------------- ---QCSVGIL------------KNICLLSYYLMLHYNK---H-----TLKRIDL-IFMNM -------FISNFFIIFSRIVLQTM------------QTFGMELFFNVFVCKFPMYTERV- ---GRSVSIGTICLLSVF-------QAITISPSDS-CLN-GLKVKVP------KYISLSI FLC---------WVLFLGLNMISPMYVYIKWNSNNVTY-KITSNYCFSL-GHDEFTGPMI TTFFVFPEVLFA-----------ILIV-CSGSLMVVILYRHKQR----VQHIHSTYAP-- ---TRTSHESRATKNILVLVSIFIG---FYSLSSILHTCLAL------------FCGA-- --GWW-----------MIN------------------ITVIIHL---------------- ---C--FP-----------------------T-L--G---P--------------FI--- ----------------------------------------VTH-------DSA------L ----P-RFSLS---------------------------WIRNTGRT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >231-m ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MVN-- ----------DKMDSK---------NLAI---FV---------ILIL------------- ---QCSVGIL------------KNICLLSYYLMLHYNK---H-----TLKRIDL-IFMNM -------FIANFFIIFSRIVLQTM------------QTFGMELFFNVFVCKFPMYTERV- ---GRSVSIGTICLLSVF-------QAITISPSDS-CLN-GLKVKVP------KYINLSI FLC---------WVLFLGLNMISPMYVYIKWNSNNVTY-KRTSNYCFSL-GHDEFTGPMI TTFFVFPEVLFA-----------ILIV-CSGSLMVNILYRHKQR----VQHIHSTYAP-- ---TRTSHESRATKNILVLVSLFIG---FYSLSSILHTCVAL------------FCGA-- --GWW-----------MIN------------------ITVIIHL---------------- ---C--FP-----------------------T-L--G---P--------------FI--- ----------------------------------------VTQ-------DTA------L ----P-RFSLS---------------------------WIRNTGRT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >231.1-x ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MVN-- ----------DKMDSK---------NLAI---FV---------ILIL------------- ---QCSVGIL------------KNICLLSYYLMLHYNK---H-----TLKQIDL-IFMNM -------FIANFFIIFSRIVLQTM------------QTFGMELFFNVFVCKFPMYTERV- ---GRSVSIGTICLLSVF-------QAITISPSDS-CLN-GLKVKVP------KYISLSI FLC---------WVLFLWLNMISPMYVYIKWNSNNVTY-KRTSNYCFSL-GHDEFTGPMI TTFFVFPEVLCA-----------ILIV-CSGSLMVIILYRHKQR----VQHIHSTYAP-- ---TRTSHESRATKNILVLVSLFIG---FYSLSSILHTCVAL------------FCGA-- --GWW-----------MIN------------------ITVIIHL---------------- ---C--FP-----------------------T-L--G---P--------------FI--- ----------------------------------------VTH-------DTA------L ----P-RFSLS---------------------------WIRNTGRT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >231-z ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MVN-- ----------DKMDSK---------NLAI---FV---------ILIL------------- ---QCSVGIL------------KNICLLSYYLMLHYNK---H-----TLKQIDL-IFMNM -------FIANFFIIFSRIVLQTM------------QTFGMELFFNVFVCKFPMYTERV- ---GRSVSIGTICLLSVF-------QAITISPSDS-CLN-GLKVKVP------KYISLSI FLC---------WVLFLWLNMISPMYVYIKWNSNNVTY-KRTSNYCFSL-GHDEFTGPMI TTFFVFPEVLCA-----------ILIV-CSGSLMVIILYRHKQR----VQHIHSTYAP-- ---TRTSHESRATKNILVLVSLFIG---FYSLSSILHTCVAL------------FCGA-- --GWW-----------MIN------------------ITVIIHL---------------- ---C--FP-----------------------T-L--G---P--------------FI--- ----------------------------------------VTH-------DTA------L ----P-RFSLS---------------------------WIRNTGRT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >231-p ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MVN-- ----------DRMDSK---------NLAI---FV---------ILIL------------- ---QCSMGIL------------KNFCLLSYYLMLHYNK---H-----TLKPVDF-IFMNM -------FIANFFIIFSRIVLQTM------------ETFGKELFFNVFVCKFPMYTERV- ---GRSVSIGTICLLSVF-------QAITISPSDS-CLS-GLKVKVS------KYISLSI FLC---------WVLFLGLNMIPPMYAYIKCNSNNVTH-IRTSKYCFSL-GHDEFTGSMV TTVFVFPEVFFA-----------ILIV-WSGSLMVVILYRHKQR----VQHIHCTYVS-- ---NRTSHESRATKSILVLVSVFIG---FYSLSSILHTCVAL------------FCGA-- --GWW-----------LVN------------------ITVIIHL---------------- ---C--FP-----------------------T-L--G---P--------------FI--- ----------------------------------------VSH-------GTA------L ----P-RFSLS---------------------------CIRNTGRP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >230-c -------------------------------------------------MRNVWWHI--- ------------------------------------------------------------ ---------------------------------------------------LKSVFLS-- ----------HNMDAR---------NWGI---GI---------IYLL------------- ---QSTVGIL------------GNISLLSYYLVIYYKK---H-----KQKPTDL-IIMHL -------IIVNILIVLSKGVSVTM------------AAFGLKLFFDDWSYQFFMYVLRV- ---SRSMSIVTICLLSVI-------QAITIIPRNS-CWK-NIRVKSP------KDISLCI SLC---------WVLYIFINVIFPLYMSITFTGKNKTK-DTNFKLYTIV-GYDKNTVSLY ISFFVFPEILFS-----------GLIT-WSGRSVIVILYRHKQQ----VQYIRSTHAS-- ---PSSTHESRAIQSILVLVSIFMV---FYTLSAILHAYNAL------------FHSS-- --NWW-----------LMN------------------FTNIITL---------------- ---C--IP-----------------------T-S--I---P--------------FV--- --------L-------------------------------MSQ-------SSP------L ----S-KPCFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >230-s -------------------------------------------------MRSVWWHI--- ------------------------------------------------------------ ---------------------------------------------------LKSVFLS-- ----------HNMDAR---------NLVI---GI---------IYLL------------- ---QSTVGIL------------GNTFLLSYYLVIYYKK---H-----KRKPTDL-IIMHL -------IIVNILIMLSKGMSITM------------GALGLKLFFDDWSYQFFMYVLRV- ---FRSMSIVTICLLSVF-------QTITIIPRNS-CWK-NIRVKSP------KDISLCI SLC---------WVLYIFINVIFPLYMSITFTGKNKTK-DTNFKLYTIV-GYDKNTVSLY ITFFVFPEILFS-----------GLIT-WSGSSVIVILYRHKQQ----VQYVRSTHAS-- ---SSSTPESRAIQSILVLVSIFMA---FYTFSAILHAYNAL------------FHSS-- --NWW-----------LMT------------------FANIISL---------------- ---C--IP-----------------------T-S--I---P--------------FV--- --------L-------------------------------MSQ-------SSP------L ----S-KLCFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >230-m -------------------------------------------------MRSVWWHI--- ------------------------------------------------------------ ---------------------------------------------------LKSVFLS-- ----------HNMDAR---------NLGT---GI---------IYLL------------- ---QSTVGIL------------GNTFLLSYYLIIYYKK---H-----KRKPTDL-IIMHL -------IIVNILIMLSKGMSITM------------GALGLKLFFDDWSYQFFMYVLRV- ---FRSMSIVTICLLSVF-------QTITIIPRNS-CWK-NIRVKSP------KNISLCI SLC---------WVLYIFINVIFPLYMSITFTGKNKTK-DTNFKLYTIV-GYDKNTVSLY ITFFVFPEILFS-----------GLIT-WSGSSVIVILYRHKQQ----VQYVRSTHAS-- ---PSSTPESRAIQSILVLVSIFMA---FYTLSAILHAYNAL------------FHSS-- --NWW-----------LMT------------------FANIISL---------------- ---C--IP-----------------------T-S--I---P--------------FV--- --------L-------------------------------MSQ-------SSP------L ----S-KLCFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >230-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDAR---------NLGI---GI---------IYLL------------- ---QSTVGIL------------GNTFLLSYYLVIYYKK---H-----KRKPTDL-IIMHL -------IIVNILIMLSKGVSITM------------GALGLKLFFDDWSYQFFMYVLRV- ---FRSMSIVTICLLSVF-------QTITIIPRNS-CWK-NIRVKSP------KDISLCI SLC---------WVLYIFINVIFPLYMSITFTGKNKTK-DTNFKLYTIV-GYDKNTVSLY ITFFVFPEILFS-----------GLIT-WSGSSVIVILYRHKQQ----VQYVRNTHAS-- ---SSSTPESRAIQSILVLVSIFMA---FYTLSAILHAYNAL------------FHSS-- --NWW-----------LMT------------------FANIISL---------------- ---C--IP-----------------------T-S--I---P--------------FV--- --------L-------------------------------MSQ-------SSP------L ----S-KLCFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >230-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDAR---------NLGI---GI---------IYLL------------- ---QSTVGIL------------GNTFLLSYYLVIYYKK---H-----KRKPTDL-IIMHL -------IIVNILIMLSKGVSITM------------GALGLKLFFDDWSYQFFMYALRV- ---FRSMSIVTICLLSVF-------QTITIIPRNS-CWK-NIRVKSP------KDISLCI SLC---------WVLYIFINVIFPLYMSITFTGKNKTK-DTNFKLYTIV-GYDKNTVSLY ITFFVFPEILFS-----------GLIT-WSGSSVIVILYRHKQQ----VQYVRNTHAS-- ---SSSTPESRAIQSILVLVSIFMA---FYTLSAILHAYNAL------------FHSS-- --NWW-----------LMT------------------FANIISL---------------- ---C--IP-----------------------T-S--I---P--------------FV--- --------L-------------------------------MSQ-------SSP------L ----S-KLCFL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >230-p -------------------------------------------------MRSVWLHI--- ------------------------------------------------------------ ---------------------------------------------------LKSVFLS-- ----------HNMDAR---------NLGI---GI---------IYLL------------- ---QSTVGIL------------GNISLLFYYLVIYYKI---P-----KRKPTDL-IIMHL -------IIVNILIILSKGMSKTM------------TTFGLKLFFNDWSYQFFMYVLRV- ---FRSMSVVTICLLSVF-------QAITIIPRNS-CWK-NLRVKSP------KDISLCI SLS---------WVLYIFINLIFPLYMSITFTGKNKTE-DTNFKLYTIV-GYDKNTVSLY ISFFVFPEILFS-----------GLIT-WSGSSVIVILYRHKQR----VQYIRSTHAS-- ---LSSTPESRATQSILVLVSIFMT---FYTLSAILHAYNAV------------FHSS-- --NWW-----------LIN------------------FTNIITL---------------- ---C--IP-----------------------T-S--I---P--------------FV--- --------L-------------------------------MNK-------LSP------L ----S-KP---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal71-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MSLLFLL------------SNPLL----------Q---T-----VRDKTHG-FDSHV HNNAHNSHAANAVIILSSGVPHTM------------SAFGRNQFLNSFVCKLLLYIHGF- ---RRSISIGTSCFLSVF-------QTMTISPRES-CWK-NQNDKAG------KYIGCPI IIL---------WVFYMLINFISSLNTLNNWKSKHVTR-EQDFGYCSIV-GHNEISEFLY AALVVCPEVLFS-----------VLIS-YSRGFMIALLL--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >70-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTSR---------DLIL---GI---------FFLS------------- ---QIVLGML------------GNSALLCCFIIADFTE---V-----RTRPIDL-IVKHL -------TWANIMVVLCKGIPQTM------------TAFGHTYFLDDITCKLVFYLHRV- ---CRGFSLGCTCLLSVF-------QAITISLINS-KSA-QFKARAP------KIISSSL VLC---------WSLCLLVNTFMILTVTDMRDKRNLTE-FRQLVYCSAV-KNFKHIHTVY AIILAFSDVICL-----------GLMV-CTSGSMVLFLVKHKQK----VQYIHRS-LA-- ---TKSFNETKATQSICMLVSSFVV---LYGTSFILMMYFSF------------QDRT-- --DTW-----------LVS------------------VNVAMSA---------------- ---C--FP-----------------------A-L--C---P--------------FL--- --------L-------------------------------TRN-------YTR------V ----F-KLCSI------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >70.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTSR---------DLTL---GI---------FFLS------------- ---QIVLGML------------GNSALLCCFIIADFTG---V-----RTRPIDL-IVKHL -------TWANIMVVLCKGIPQTM------------TAFGHTYFLDDITCKLVFYLHRV- ---CRGFSLGCTCLLSVF-------QAITISLNNS-KSA-QFKARAP------KIISSSL VLC---------WSLCLLVNTFMILTVTDMKDKRNLTE-FRQLVYCSAV-KNFKHIHTVY AIILAFSDAICL-----------GLMV-CTSGSMVLFLVKHKQK----VQYIHRS-LA-- ---TKSFNETKATQSICMLVSSFVV---LYGTSFILMMYFSF------------QDGT-- --DTW-----------LVS------------------VNVAMSA---------------- ---C--FP-----------------------A-L--C---P--------------FL--- --------L-------------------------------TRN-------YTR------V ----F-KLCSI------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >70.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------ML------------GNSALLCCFIIADFTG---V-----RTRPIDL-IVKHL -------TWANIMVVLCKGIPQTM------------TAFGHTYFLDDITCKLVFYLHRV- ---CRGFSLGCTCLLSVF-------QAITISLNNS-KSA-QFKARAP------KIISSSL VLC---------WSLCLLVNTFMILTVTDMKDKRNLTE-FRQLVYCSAV-KNFKHIHTVY AIILAFSDAICL-----------GLMV-CTSGSMVLFLVKHKQK----VQYIHRS-LA-- ---TKSFNETKATQSICMLVSSFVV---LYGTSFILMMYFSF------------QDGT-- --DTW-----------LVS------------------VNVAMSA---------------- ---C--FP-----------------------A-L--C---P--------------FL--- --------L-------------------------------TRN-------YTR------V ----F-KLCSI------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >70-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTSR---------DLTL---GI---------FFLS------------- ---QIVLGML------------GNSALLCCFIIADFTG---V-----RTRPIDL-IVKHL -------SWANIMVVLCKGIPQTM------------TAFGHTYFLDDITCKLVFYLHRV- ---CRGFSLGCTCLLSVF-------QAITISLNNS-KSA-QFKARAP------KIISSSL VLC---------WSLCLLVNTFMILTVTDMRDKRNLTE-FRQLVYCSAV-KNFKHIHTVY AIILAFSDVICL-----------GLMV-CTSGSMVLFLVKHKQK----VQYIHRS-LA-- ---TKSFNETKATQSICMLVSSFVV---LYGTSFILMMYFSF------------QDGT-- --DTW-----------LVS------------------VNVAMSA---------------- ---C--FP-----------------------A-L--C---P--------------FL--- --------L-------------------------------TRN-------YTR------V ----F-KLCSI------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >70-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTSR---------DLTL---GI---------FFLS------------- ---QIVLGML------------GNSALLCCFIIADFTG---V-----RTRPIDL-IVKHL -------TWANIMVVLCKGIPQTM------------TAFGHTYFLDDITCKLVFYLHRV- ---CRGFSLGCTCLLSVF-------QAITISLNNS-KSA-QFKARAP------KIISSSL VLC---------WSLCLLVNTFMILTVTDMRDKRNLTE-FRQLVYCSAV-KNFKHIHTVY AIILAFSDVICL-----------GLMV-CTSGSMVLFLVKHKQK----VQYIHRS-LA-- ---TKSFNETKATQSICMLVNSFVV---LYGTSFILMMYFSF------------QDGT-- --DTW-----------LVS------------------VNVAMSA---------------- ---C--FP-----------------------A-L--C---P--------------FL--- --------L-------------------------------TRN-------YTR------V ----F-KLCSI------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >88.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MPPS---------DTNF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFVK--PY-----LKKLIDS-VFMHL -------TIVNMSTIMFTLLKDIM------------FSFRVPNFLDDVGCKAVLFSFRL- ---SRGLSICTTSVLSTF-------QVITITPSKS-KFVSWLKPRLS------TWIFSSL LCS---------WIINLLIYGFMIDLVVAKTNMTLVGR-GFSHGYCQRK-KFGKQNSEWL FSFLITHDFFYM-----------SVMM-WASLYMVIFLYRHRKT----AQHLHSPNLS-- ---SQSSPEHKATHSILFLVSCFVL---TYWLNNSITLYG-FYTK---------EKIPR- ----------------LEA------------------IDTILTA---------------- ---S--YP-----------------------T-I--C---P--------------FL--- --------L-------------------------------MKN-------NKV------I ----L-QFISSFSVL-------------------------RMTCFQS------SLPG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >88-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MPPS---------DTIF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFFK--PH-----LKKLIDS-VFMHL -------TIVNMSTIMFTLLKDIM------------FSFRVPNFLDDVGCKAVFFSLRV- ---SRGLSICTTSVLSTS-------QVITITPNNP-TFVSWLKPRLS------TWIFSSL LCS---------WIINLLIYGFMIDLVVAKTNMTLVGR-GFSHGYCQRK-KFGKQNSEWL FSFLIIHDFFYM-----------SVMM-WASLYMVIFLYRHRKL----AQHLHSPNLS-- ---SQSSPERKATHSILFLVSCFVL---TYWLNNFITFYG-FNTK---------ERNPR- ----------------LEA------------------INTILIT---------------- ---S--YP-----------------------T-I--C---P--------------FL--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTCFQS------SLPG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >88-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MHL -------TIVNMSTIVFTLLKDIM------------FSFRVPNFLDDVGCKAVFFSLRV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WIINLLIYGFMIDLVVAKTNMSLVGR-GFSHGYCQRK-KFGKQNSEWL FSFLITHDFFYM-----------SVMM-WASLYMVIFLYRHRKL----AQHLHSPNLS-- ---SQSSPERKATHSILFLVSCFVL---TYWLNNFITFYG-FNTK---------ERNPR- ----------------LEA------------------INTILIT---------------- ---S--YP-----------------------T-I--C---P--------------FL--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTCFQS------SLPG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >88.3-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLPS---------DTIF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFFK--PH-----LKKLIDS-VFMHL -------TIVNMSTIMFSMIKDIM------------FSFRVPNFLDDVGCKAVLFSFRL- ---SRGLSICTTSVLSTF-------QVITITPSKS-KWVSWLKPRLS------TWIFSSL LCS---------WLINLLIYGYMLDLVIAKTNNSHVGR-GYSHGYCQNK-KYGTHDSGWF FSLIITHDLIYV-----------AVMM-WASLYMVIFLYRHR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >88.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLPS---------DTIF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFFK--PH-----LKKLIDS-VFMHL -------TIVNMSTIMFSMIKDIM------------FSFRVPNFLDDVGCKAVLFSFRL- ---SRGLSICTTSVLSTF-------QVITITPSKS-KWVSWLKPRLS------TWIFSSL LCS---------WLINLLIYGYMLDLVIAKTNNSHVGR-GYSHGYCQNK-KVGKQNSEWF FSFLITHDFFYM-----------SVMM-WASLYMVIFLYRHR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >86.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLPS---------DTIF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFFK--PH-----LKKLIDS-VFMHL -------TIVNMSTIMFSLIKDIM------------FSFRVPNFLDDIGCKAVLFSFRV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLLIYGYMLDLVIAKTNNSHVGR-GYSHGYCQNK-KYGSHDSGWF FSLIITHDLIYV-----------AVMM-WASLYMVIFLYRHRKT----AQHLHSPNLS-- ---SQPSPERKATHSILFLVSCFVL---TYWLNNSITLYG-FYTK---------EKIPR- ----------------LEA------------------IDTILTT---------------- ---S--YP-----------------------T-I--C---P--------------FL--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTSFQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >86-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLPS---------DTIF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFFK--PH-----LKKLIDS-VFMHL -------TIVNMSTIMFSLVKDIM------------FSFRVPNFLDDIGCKTVLFSFRV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLLIYGYMLDLVIAKTNNSHVGR-GYSHGYCQNK-KYGSHNSGWF FSLIITHDLIYV-----------TVMM-WASLYMVIFLYRHRKT----AQHLHSPNLS-- ---SQPSPERKATHSILFLVSCFVL---TYWLNNSITLYG-FYTK---------EKIPR- ----------------LEA------------------IDTILTT---------------- ---S--YP-----------------------T-I--C---P--------------FL--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTSFQS------SLHS--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >86-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------MLDLVIAKTNNSHVGR-GYSHGYCQNK-KYGSHNSGWF FSLIITHDLIYV-----------TVMM-WASLYMVIFLYRHRKT----AQHLHSPNLS-- ---SQPSPERKATHSILFLVSCFVL---TYWLNNSITLYG-FYTK---------EKIPT- ----------------LEA------------------IDTILTT---------------- ---S--YP-----------------------T-I--C---P--------------FL--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTSFQS------SLHS--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >86.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------MSVDTHCPE--PG-----FEAL--------- ---------------------HTQ------------SKRRVPNFLDDIGCKAVLFSFRV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLLIYGYMLDLVIAKTNNSHVGR-GYSHGYCQNK-KYGSHDSGWF FSLIITHDLIYV-----------AVMM-WASLYMVIFLYRHRKT----AQHLHSPNLS-- ---SQPSPERKATHSILFLVSCFVL---TYWLNNSITLYG-FYTK---------EKIPR- ----------------LEA------------------IDTILTT---------------- ---S--YP-----------------------T-I--C---P--------------FL--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTSFQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >86/88-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLLS---------DTIF---QI---------FLVF------------- ---QFCLGVI------------GNSSLLMLYIYTFIFR--PH-----FKKLIDS-VFMHL -------TIVNMSTIMLSMIKDIM------------FSFRVPNFLDDVGCKAVLFSFRV- ---SRGLSICTTSVLSTS-------QVITISPSNS-KLASWLKPRLS------TWTFSSL LFS---------WLINLLIYGLMLDFVIAKTNITLVGR-GYSHGYCQNK-NFGNQNSGWF FGLIIIHDLIYV-----------AVMM-WASLYMVIFLIRHRKT----AQHLHSPNLS-- ---SQPSPERKATHSILSLVSCFVL---TYWLNNSITLYG-FYTK---------EKIPR- ----------------LEA------------------INTILTT---------------- ---S--YP-----------------------T-I--C---T--------------FL--- --------L-------------------------------MKN-------NKV------I ----L-QFISSFSVL-------------------------RMTCFQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------MLDMVIAKTNKTHVGS-GYSDGYCQNK-HFGNQNSGSF FSLILTHDLFYV-----------AVMV-WASLYMVIFLYRHYKR----SQHLHSRSIS-- ---SQSSPERKATHNILSLVSFFVL---IYCLNNSITLYC-FYTK---------EKIPR- ----------------LES------------------INAILTA---------------- ---C--YP-----------------------T-I--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QLASSFSVL-------------------------RMTCLQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MFPS---------DTFF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFFK--PH-----FKKLVDS-VFMHL -------TIVNMLTIAFTLIKDIM------------LSFGVPNFLDDIGCKTVLFSFRV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLVIYGYMLDMVIAKTNKTDVGN-GYSDGYCQNK-HFGNHNSGSF FSLILTHDLFYV-----------AVMV-WASLYMVIFLYRHYKR----SQHLHSRSLS-- ---SQSSPERKATHNILSLVSSFVL---IYCLNNSITLYG-FYTK---------EKIPR- ----------------LES------------------INAILTT---------------- ---C--YP-----------------------T-V--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QFASSFSVL-------------------------RVTCLQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MFPS---------DTFF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFFK--PH-----FKKLVDS-VFMHL -------TIVNMLTIAFTLIKDIM------------LSFGVPNFLDDIGCKTVLFSFRV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLVIYGYMLDMVIAKTNKTDVGN-GYSDGYCQNK-HFGNHNSGSF FSLILTHDLFYV-----------AVMV-WASLYMVIFLYRHYKR----SQHLHSRSLS-- ---SQSSPERKATHNILSLVSSFVL---IYCLNNSITLYG-FYTK---------EKIPR- ----------------LES------------------INAILTT---------------- ---C--YP-----------------------T-V--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QFASSFSVL-------------------------RVTCLQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MFPS---------DTFF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFFK--PN-----FKKLVDS-VFMHL -------TIVNMLTIAFTLIKDIM------------LSFGVPNFLDDIGCKTVLFSFRV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLVIYGYMLDMVIARTNKTHVGN-GYLDGYCQNK-HFGNHNSGSF FSLILTHDLFYV-----------AVMV-WASLYMVIFLYRHYKR----SQHLHSRSLS-- ---SQSSPERKATHNILSLVSCFVL---IYCLNNSITLYG-FYTK---------EKIPR- ----------------LES------------------INAILTT---------------- ---C--YP-----------------------T-V--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QFASSFSVL-------------------------RMTCLQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MFPS---------DTFF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFFK--PN-----FKKLVDS-VFMHL -------TIVNMLTIAFTLIKDIM------------LSFGVPNFLDDIGCKTVLFSFRV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLVIYGYMLDMVIARTNKTHVGN-GYSDGYCQNK-HFGNHNSGSF FSLILTHDLFYV-----------AVMV-WASLYMVIFLYRHYKR----SQHLHSRSLS-- ---SQSSPERKATHNILSLVSCFVL---IYCLNNSITLYG-FYTK---------EKIPR- ----------------LES------------------INAILTT---------------- ---C--YP-----------------------T-V--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QFASSFSVL-------------------------RMTCLQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MFSS---------DTFF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFFFK--PH-----FKKLVDS-VFMHL -------TIVNMLTIAFTLIKDIM------------LSFGVPNFLDDIGCKTVLFSFRV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLVIYGYMLDMVIAKTNKTHVGN-GYSDGYCQNK-HFGNHNSGSF FSLLLTHDLFYV-----------AVMV-WASLYMVIFLYRHYKR----SQHLHSRSLS-- ---SQSSPERKATHNILSLVSCFVL---IYCLNNSITLYG-FYTK---------EKIPR- ----------------LES------------------INAILTT---------------- ---C--YP-----------------------T-V--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTCHQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------MSVD--PHCAERGFEAL--------- ----------------HTQSKR-----------------------------------RV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLVIYGYMLDMVIAKTNKTDVGN-GYSDGYCQNK-HFGNHNSGSF FSLILTHDLFYV-----------AVMV-WASLYMVIFLYRHYKR----SQHLHSRSLS-- ---SQSSPERKATHNILSLVSSFVL---IYCLNNSITLYG-FYTK---------EKIPR- ----------------LES------------------INAILTT---------------- ---C--YP-----------------------T-V--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QFASSFSVL-------------------------RVTCLQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------MSVD--PHCAERGFEAL--------- ----------------HTQSKR-----------------------------------RV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLVIYGYMLDMVIAKTNKTHVGN-GYSDGYCQNK-HFGNHNSGSF FSLLLTHDLFYV-----------AVMV-WASLYMVIFLYRHYKR----SQHLHSRSLS-- ---SQSSPERKATHNILSLVSCFVL---IYCLNNSITLYG-FYTK---------EKIPR- ----------------LES------------------INAILTT---------------- ---C--YP-----------------------T-V--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTCHQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89.4-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------MSVD--PHCAERGFEAL--------- ----------------HTQSKRSTSVQDSRKPGKGVRSFGIG------------FTDRV- ---SRGLSICTTSVLSTF-------QVITITPSNS-KWASWLKPRLS------TWIFSSL LCS---------WLINLVIYGYMLDMVIAKTNKTHVGN-GYSDGYCQNK-HFGNHNSGSF FSLLLTHDLFYV-----------AVMV-WASLYMVIFLYRHYKR----SQHLHSRSLS-- ---SQSSPERKATHNILSLVSCFVL---IYCLNNSITLYG-FYTK---------EKIPR- ----------------LES------------------INAILTT---------------- ---C--YP-----------------------T-V--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTCHQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89.3-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------MSVD--PHCAERGFEAL--------- ----------------HTQSKR-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------RHYKR----SQHLHSRSLS-- ---SQSSPERKATHNILSLVSCFVL---IYCLNNSITLYG-FYTK---------EKIPR- ----------------LES------------------INAILTT---------------- ---C--YP-----------------------T-V--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTCHQS------SLHG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLPS---------DTFF---QI---------FLIF------------- ---QFCLGVI------------GNSSLLMLYVYTFLFK--PN-----FKKLIDS-VFMHL -------TIVNMLTITFTLIKDIM------------LSFGVPHFLDDIGCKAVLFSCRV- ---SRGLSICTTSVLSTS-------QVITISPSNS-KLASWLKPRLS------TWIFSSL LCS---------WFINVVIYGYMLDMVIAKNNKTQVGN-GYSDGYCQNK-YFGNHNSGSF FSLILTHDLFYV-----------AVMV-WASFYMVIFLYRHYKR----AQHLHSPSLS-- ---SQSSPERKATHSILSLVSCFVL---IYCLNNSITLYG-FYTK---------EKIPR- ----------------LES------------------INSILTT---------------- ---C--YP-----------------------T-I--C---P--------------FF--- --------L-------------------------------MKN-------NKV------I ----L-QFASSFSVL-------------------------RMTCLQS------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >89.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------MVDMVIAKTNNTHVGH-GYLDGYCQNK-QFGNHNSGSF FSIIIIHDLFYV-----------AVMM-WASLYLVIFLYRHRKK----SQHLHSPSLS-- ---SQPSPEHKATHSILSLVSCFVL---IYWLNNSVSLYG-FYAK---------EKIPI- ----------------LES------------------INVILTA---------------- ---C--YP-----------------------T-I--C---P--------------FL--- --------L-------------------------------MKN-------NKV------I ----L-QFTSSFSVL-------------------------RMTCLKV--------HSTAE QKSTL---------------------------------VIKTVS---------------- ------------------------------------------------------------ ------------- >85-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSFP--------SKTLL---GV---------IFIS------------- ---EFCVGII------------GNSLLLVLYVYNFLVK--AH-----FNRQIDP-IFMHL -------MIVNMLTIIFSMIPYIT------------SSFGVPSFLNSAGCKAFQYVYRV- ---TRAMSISTTSILSSF-------QAITITPSNS-KWA-WLKPKLS------TWTFCSF LFS---------WFINLVIYVQLIKTVIAKTNYTDVDY-GYSHVYCGSS-PVEYPNPGLF LSVIITRDLLFL-----------VIMM-WTSLYMVTLLFRHHKR----AQHLRNPRLS-- ---SQKSPEHKATHTILLLVNCFVF---FYLLNIFATLYDRFCTR---------ERTPS- ----------------LGA------------------IIAIMAS---------------- ---F--YP-----------------------T-L--C---P--------------FL--- --------L-------------------------------MNT-------NKI------I ----S-QCISSLLVFI---------------EPLVIDM---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >85-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSFP--------SNTLL---GV---------FFIS------------- ---EFCVGVI------------GNSLLFVLYVYNFWVK--VH-----FSRLIDP-IFMHL -------MIVNILTIIFAMIPYIT------------SSFGVPSFLDNAGCKAFVYVYRV- ---SRAMSISSTSILSTF-------QAITITPSNS-KLA-WLKPKLS------KWTFCTF LFS---------WFINLVIYVHLIENVVAKTNYTDVDY-GYSHVYCGSG-PVEYPNPGLF LSIIITRDLLFL-----------VIMI-WTSLYMVTLLYRHRKR----ARHLRNPSLS-- ---SQQSPEHKATRTILLLVSCFVF---FYLLNNLATLYDRFYIR---------GKTGN- ----------------LGA------------------IITIMAS---------------- ---F--YP-----------------------T-L--C---P--------------FL--- --------L-------------------------------MNN-------NKI------I ----S-QCISSIHIFK---------------ESLVTDMKPRCPHQQT------SLSSD-- -----------LC------------------------DMLKVVW--------LW------ --------------------------------NPY------------------------- ------------- >85.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLFP--------SNTIL---GV---------FVIS------------- ---EFCVGVL------------GNSLLLMLYIFNFWVK--AH-----FNRQIDP-IFMHL -------MIVNMLTIIFAMIPYIT------------SSFGVPSFLHDAGCKAFVYVYRV- ---SRAMSISSTSILSTF-------QAITITPSNS-KWA-WLKPKLS------KWTFCTF LFS---------WFINMVIYVHLIENVIAKTNYTSVNS-GYSHVYCESS-PVEYPNPGFF LGVIITRDLVLL-----------VIMM-STSLSMVTLLYRHHKR----AQHLRNQRLS-- ---SQKSPEQKATHTILLLVNCFVF---FYLLNNLITLYDRFYTR---------GKTGN- ----------------LGA------------------IITIVAS---------------- ---F--YP-----------------------T-L--C---P--------------FL--- --------L-------------------------------MNS-------NKVYFFPSYI ----Q-RAIGD------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >85.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLFP--------SNTIL---GV---------FVIS------------- ---EFCVGVL------------GNSLLLMLYIFNFWVK--AH-----FNRQIDP-IFMHL -------MIVNMLTIIFAMIPYIT------------SSFGVPSFLHDAGCKAFVYVYRV- ---SRAMSISSTSILSTF-------QAITITPSNS-KWA-WLKPKLS------KWTFCTF LFS---------WFINMVIYVHLIENVIAKTNYTSVNS-GYSHVYCESS-PVEYPNPGFF LGVIITRDLVLL-----------VIMM-STSLSMVTLLYRHHKT----AQHLRNQRLS-- ---SQKSPEQKATHTILLLVNCFVF---FYLLNNLITLYDRFYTR---------GKTGN- ----------------LGA------------------IITIVAS---------------- ---F--YP-----------------------T-L--C---P--------------FL--- --------L-------------------------------MNS-------NKVYFFPSYI ----Q-RAIGD------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >85-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLFP--------SNTIL---GV---------FVIS------------- ---EFCVGVL------------GNSLLLMLYIFNFWVK--AR-----FNRQIDP-IFMHL -------MIVNMLTIIFAMIPYIT------------SSFGVPSFLHDAGCKAFVYIYRV- ---SRAMSISSTSILSTF-------QAITITPSNS-KWA-WLKPKLS------KWTFCTF LFS---------WFINMVIYVHLIENVIAKTNYTGVNY-GYSHVYCESS-PVEYPNPGFF LGVIITRDLVLL-----------VIMM-WTSLSMVTLLYRHHKR----AQHLRNPRLS-- ---SQKSPEHKATHTILLLVNCFVF---FYLLNNLITLYDRFYTR---------GRTGN- ----------------LGA------------------IITIVAS---------------- ---F--YP-----------------------T-L--C---P--------------FL--- --------L-------------------------------MNS-------NKMYFFPSYI ----Q-RAIGD------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >85-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLFP--------SNTIL---GV---------FVIS------------- ---EFCVGVL------------GNSLLLMLYIFNFWVK--AR-----FNRQIDP-IFMHL -------MIVNMLTIIFAMIPYIT------------SSFGVPSFLHDAGCKAFVYVYRV- ---SRAMSISSTSILSTF-------QAITITPSNS-KWV-WLKPKLS------KWTFCTF LFS---------WFINMVIYVHLIENVIAKTNYTGVNY-GYSHVYCESG-PVEYPNPGFF LGVIITRDLVLL-----------VIMM-WTSLSMVTLLYRHHKR----AQHLRNPRLS-- ---SQKSPEHKATHTILLLVNCFVF---FYLLNNLITLYDRFYTR---------GRTEN- ----------------LGA------------------IITIVAS---------------- ---F--YP-----------------------T-L--C---P--------------FL--- --------L-------------------------------MNS-------NKVYFFPSYI ----Q-RAIGD------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >85-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLFP--------SNTIL---GV---------FVIS------------- ---EFCVGVL------------GNSLLLMLYIFNFWVK--AR-----FNRQIDP-IFMHL -------MIVNMLTIIFAMIPYIT------------SSFGVPSFLHDAGCKAFVYVYRV- ---SRAMSISSTSILSTF-------QAITITPSNS-KWA-WLKPKLS------KWTFCTF LFS---------WFINMVIYVHLIENVIAKTNYTGVNY-GYSHVYCESS-PVEYPNPGFF LGVIITRDLVLL-----------VIMM-WTSLSMVTLLYRHHKR----AQHLRNPRLS-- ---SQKSPEHKATHTILLLVNCFVF---FYLLNNLITLYDRFYTR---------GRTEN- ----------------LGA------------------IITIVAS---------------- ---F--YP-----------------------T-L--C---P--------------FL--- --------L-------------------------------MNS-------NKVYFFPSYI ----Q-RAIGD------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >87-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MYLR---------NLIS---GF---------FLLS------------- ---QVFIALM------------GNLLLFILHMYIFLVQ--PH-----QKKPIDI-IFTHL -------MLVNVFSIVFKLMPDVM------------RSFAVRILFHDVACKAVLYAYSA- ---TRGLSLCTILLLSVF-------QAITLSSKHS-KWA-WLKSKLE------SCIFPLF LIM---------WIINTFLYFSMVENIKEKINFTFVDS-RYSQIYCRSS-QVRHHTTKSL VTALIIRDVLFV-----------FLMI-WSSLYMVSLLFRHNRS----TRHVHSFSVS-- ---LHASSEKRATHSILLLVAFFVF---FYCSNTFVTFFSLYQPK---------SNP--- ----------------VLDL-----------------IGGVLSS---------------- ---G--YP-----------------------T-V--C---P--------------YV--- --------L-------------------------------LNN-------RKL------I ----S-KFISSFSNF-------------------------KCTFFA-------------- -----------------RGCHC-------------------------------------- ------------------------------------------------------------ ------------- >87-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MFLR---------NLIS---GF---------FLLS------------- ---EVFIGLM------------GNLLLFILYMYIFLIQ--PH-----QKKPIDM-IFTHL -------MLVNVLSIMFKLIPDVM------------RSFAVRILFHDVACKAVLYAYSV- ---TRGLSLCTILLLSVF-------QAITLSSKHS-KWA-WLKSKLE------SCIFPLF LII---------WIINTFLYLPMVENVKGKINFTLMDS-RYSQIYCRSS-QVRHHTTMSL VTALIIRDVLFV-----------FLMI-WSSLYMVSLLFRHNRS----TRHVHSFSVS-- ---LHASSEKRATHSILLLVAFFVF---FYCSNTFVTFYSLYRPK---------SNP--- ----------------VLDL-----------------IGGVLSS---------------- ---G--YP-----------------------T-V--C---P--------------YV--- --------L-------------------------------LNN-------RKL------I ----S-KFISSFSQF-------------------------KCTFFA-------------- -----------------RGCHG-------------------------------------- ------------------------------------------------------------ ------------- >87.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MYLR---------NLIS---GF---------FLLS------------- ---EVFIGLM------------GNLLLFILYMYIFLVQ--PH-----QKKPIDM-IFTHL -------MLVNVLSIMFKLMPDVM------------RSFAVRILFHDVACKAVLYAYSV- ---TRGLSLCTILLLSVF-------QAITLSSKHS-KWA-WLKSKLE------SCIFPLF LIM---------WIINTFLYLPMVENVKGKINFTFVDS-RYSQIHCRSS-QVRHHTTKSL VTALIIRDVLFV-----------FLMI-WSSLYMVSLLFRHNRS----TRHVHSFSVS-- ---LHASSEKRATHSILLLVAFFVF---FYCSNTFVTFYSLYRPK---------SNP--- ----------------ILDL-----------------IGGVLSS---------------- ---G--YP-----------------------T-V--C---P--------------YV--- --------L-------------------------------LNN-------RKL------I ----S-KFISSFSNF-------------------------KCTFFA-------------- -----------------RGCHG-------------------------------------- ------------------------------------------------------------ ------------- >87-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------M----------------------------------------------- ----------------------GNLLLFILYMYIFLVQ--PH-----QKKPVDM-IFTHL -------MLVNVLSIMFKLMPDVM------------RSFAVRILFHDVVCKAVLYAYSV- ---TRGLSLCTILLLSVF-------QAITLSSKHS-KWA-WLKSKLE------SCIFPLF LIM---------WIINTFLYLPMVENIKGKINFTFVDS-KYSQIYCRSS-QVRHHTTKSL VTALIIRDVLFV-----------FLMI-WSSLYMVSLLFRHNRS----TRHVHSFSVS-- ---LHASSEKRATHSILLLVAFFMF---FYCSNTFVTFYSLYQPK---------SNP--- ----------------VLDL-----------------IGGVLSS---------------- ---G--YP-----------------------T-V--C---P--------------YV--- --------L-------------------------------LNN-------RKL------I ----S-KFISSFSNF-------------------------KCTFFA-------------- -----------------RGCHC-------------------------------------- ------------------------------------------------------------ ------------- >87-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MYLR---------NLIS---GF---------FLLS------------- ---EVFVGLM------------GNLLLFILYMYIFLVQ--PH-----QKKPIDM-IFTHL -------MLVNVLSIMFKLMPDVM------------RSFAVRILFHDVVCKAVLYAYSV- ---TRGLSLCTILLLSVF-------QAITLSSKHP-KWA-WLKSKLE------SCIFPLF LIM---------WIINTFLYLPMVANIKGKINFTFVDS-RYSQIYCRSS-QVRHHTTKSL VTALIIRDVLFV-----------FLMI-WSSLYMVSLLFRHNRS----TRHVHSFSVS-- ---LHASSEKRATHSILLLVAFFMF---FYCSNTFVTFYSLYQPK---------SNP--- ----------------VLDL-----------------IGGVLSS---------------- ---G--YP-----------------------T-V--C---P--------------YV--- --------L-------------------------------LNN-------RKL------I ----S-KFISSFSNF-------------------------KCTFFA-------------- -----------------RGCHC-------------------------------------- ------------------------------------------------------------ ------------- >87-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MYLR---------NLIS---GF---------FLLS------------- ---EVFIGLM------------GNLLLFILYMYIFLVQ--PH-----QKKPIDM-IFTHL -------MLVNVLSIMFKLMPDVM------------RSFAVRILFHDVVCKAVLYAYSV- ---TRGLSLCTILLLSVF-------QVITLSSKHS-KWA-WLKSKLE------SCIFPLF FIM---------WIINTFLYLPMVENIKGKINFTFVDS-RYSQIYCRSS-QVRHHTTKSL VTALIIRDVLFV-----------FLMI-WSSLYMVSLLFRHNRS----TRHVHSFSVS-- ---LHASSEKRATHSILLLVAFFVF---FYCSNTFVTFYSLYQPK---------SNP--- ----------------VLDL-----------------IGGVLSS---------------- ---G--YP-----------------------T-V--C---P--------------YV--- --------L-------------------------------LNN-------RKL------I ----S-KFISSFSNF-------------------------KCTFFA-------------- -----------------RGCHC-------------------------------------- ------------------------------------------------------------ ------------- >87.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------M-IFTHL -------MLVNVLSIMFKLMPDVM------------RSFAVRILFHDVACKAVLYAYSV- ---TRGLSLCTILLLSVF-------QAITLSSKHS-KWA-WLKSKLE------SCIFPLF LIM---------WIINTFLYLPMVENVKGKINFTFVDS-RYSQIHCRSS-QVRHHTTKSL VTALIIRDVLFV-----------FLMI-WSSLYMVSLLFRHNRS----TRHVHSFSVS-- ---LHASSEKRATHSILLLVAFFVF---FYCSNTFVTFYSLYRPK---------SNP--- ----------------ILDL-----------------IGGVLSS---------------- ---G--YP-----------------------T-V--C---P--------------YV--- --------L-------------------------------LNN-------RKL------I ----S-KFISSFSNF-------------------------KCTFLQGDAMANLTLHTDPT LANSL---------PHEQNSHSM-----P--EYII------------------------- ---------------------------------P-------------------------- ------R------ >87.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MYLR---------NLIS---GF---------FLLS------------- ---EVFIGLM------------GNLLLFILYMYIFLVQ--PH-----QKKPIDM-IFTHL -------MLVNVLSIMFKLMPDVM------------RSFAVRILFHDVACKAVLYAYSV- ---TRGLSLCTILLLSVF-------QAITLSSKHS-KWA-WLKSKLE------SCIFPLF LIM---------WIINTFLYLPMVENVKGKINFTFVDS-RYSQIHCRSS-QVRHHTTKSL VTALIIRDVLFV-----------FLMI-WSSLYMVSLLFRHNRS----TRHVHSFSVS-- ---LHASSEKRATHSILLLVAFFCV---FLLFKYLCHLLFTLPTQ---------EQPNIG -SDWWS---------FIIR----------------------------------------- ------LP-----------------------N----CL--P------------------- --------LC-----------------------------SVEQ----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >192.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIL------------GNTLIFVRHIYMPALW---I-----EKKPVDL-ILIHL -------AFSNIIIICSTGIRDIA------------TVFYFRNFLGDTGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAITISPRTA-LWT-KLKPQTA------CQVLPFI LVF---------WIVNVLISSNLLSYIKAGSSLNKSVA-ATFIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHRR----VLYLYSSRSA-- ---NNSAPEIRATWSVLTLMTCFLF---FYWVDFILSFYTGFSVT----------HDSS- ----------------SLN------------------MKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DFR------V ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >192.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIL------------GNTLIFVRHIYMPALW---I-----EKKPVDL-ILIHL -------AFSNIIIICSTGIRDIA------------TVFYFRNFLGDTGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAITISPRTA-LWT-KLKPQTA------CQVLPFI LVF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHRR----VLYLYSSRSA-- ---NNSAPEIRATWSVLTLMTCFLF---FYWVDFILSFYTGFSVT----------HDSS- ----------------SLN------------------MKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DFR------V ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >192.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIL------------GNTLIFVRHIYMPALW---I-----EKKPVDL-ILIHL -------AFSNIIIICSTGIRDIA------------TVFYFRNFLGDTGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAITISPRTA-LWT-KLKPQTA------CQVLPFI LVF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHRR----VLYLYSSRSA-- ---NNSAPEIRATWSVLTLMTCFLF---FYWVDFILSFYTGFSVT----------HDSS- ----------------SLN------------------MKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DFR------V ----P-NVFHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >192.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIL------------GNTLIFVRHIYMPALW---I-----EKKPVDL-ILIHL -------AFSNIIIICSTGIRDIA------------TVFYFRNFLGDTGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAITISPRTA-LWT-KLKPQTA------CQVLPFI LVF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHRR----VLYLYSSRSA-- ---NNSAPEIRATWSVLTLMTCFLF---FYWVDFILSFYTGFSVT----------HDSS- ----------------SLN------------------MKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVR------V ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >192-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIL------------GNTLIFVRHIYMPALW---I-----EKKPVDL-ILIHL -------AFSNIIIICSTGIRDIA------------TVFYFRNFLGDTGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAITISPRTA-LWT-KLKPQTA------CQVLPFI LVF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLYSSRSA-- ---NNSAPEIRATWRVLTLMTCFLF---FYWVDFILSFYTGFSVT----------HDSS- ----------------SLN------------------MKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DFR------V ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >192.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIL------------GNTLIFVRHIYMPALW---I-----EKKPVDL-ILIHL -------AFSNIIIICSTGIRDIA------------TVFYFRNFLGDTGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAITISPRTA-LWT-KLKPQTA------CQVLPFI LVF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHRR----VLYLYSSRSA-- ---NNSAPEIRATWSVLTLMTCFLF---FYWVDFILSFYTGFSVT----------HDSS- ----------------SLN------------------MKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DFR------V ----L-SGLDSVGL---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >192-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIL------------GNTLIFVRHIYMPALW---I-----EKKPVDL-ILIHL -------AFSNIIIICSTGIRDIA------------TVFYFRNFLGDTGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTA-LWT-KLKPQTA------CQVLPFI LVF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLYNSRFA-- ---NNSPPEIRATWSVLILMTCFLF---FYWVDFILSFYTGFTVT----------RNFT- ----------------LLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVR------V ----P-NVSHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >192-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIL------------GNILIFVRHTYMPALW---I-----EKKPVDL-ILIHL -------AFSNLIIICSTGIRDIA------------TVFYFRNFLGDTGCKTVVYLARM- ---AQGLSICTTCLLSVV-------QAVTVNPRTS-LWT-KLKPQTA------CQVLPFI LVF---------WIVNVLISSNLLSYIKAGSGLNGSVA-AMYIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLHSSRST-- ---NNSPPEIRATWSVLTLMTCFLF---FYWVDLILSFYTGFSVT----------HDSS- ----------------SLN------------------MKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DIR------V ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >192.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIL------------GNTLIFVRHIYMPALW---I-----EKKPVDL-ILIHL -------AFSNIIIICSTGIRDIA------------TVFYFRNFLGDTGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAITISPRTA-LWT-KLKPQTA------CQVLPFI LVF---------WIVNVLISSNLLSYIKAGSGWNRSVA-ATFIGHCYML-PSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLHSSRSA-- ---NNSPPEIRATWSVLILMACFLF---FYWVDFILSFYTGFTVT----------HDST- ----------------LLN------------------IKVFLEF---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVH------P ----P-HVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >218-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MN-----------KITQ---AI---------VFLS------------- ---LAGPGIV------------GNILVFMRYVYTSALG---T-----EKRPIDL-ILIHL -------AFSNLIIICSTGVTDIV------------TVFYFRNFLGDIGCKTMVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-IWT-KLKPQTS------CQVLPFL VLF---------WIVNVLISSNLLSYIKAGSGLNRSVV-AMYIGHCYML-QSRHIIKWLF LSLMTLRDIIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLHSSRSA-- ---NNSPPEIRATWSVLILMACFLF---FYWVDFILSFYTGFTVT----------HDST- ----------------LLN------------------IKVFLEF---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVH------P ----P-HVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >218-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MN-----------KITQ---AI---------VFLS------------- ---LAGPGVV------------GNILVFMRYVYTSALG---T-----EKRPIDL-ILIHL -------ALSNLIIICSTGVTDIV------------TVFYFRNFLGDIGCKMMVYLARM- ---SRGLSICTTCLLSVV-------QAVTISPRTT-IWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKAGSGLNRSVV-ATYIGHCYML-QSRHTIKWLF LSLMTLRDVIFQ-----------SLMG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >218.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MN-----------KITQ---AI---------VFLS------------- ---LAGPGIV------------GNILVFMRYVYTSALG---T-----EKRPIDL-ILIHL -------ALSNLI-ICSTGVTDIV------------TVFYFRNFLGDIGCKMMVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-IWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-PSRHIIKWLF LSLMSLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLHSSRFA-- ---NNSPPEIRATWSVLILMAFFLF---FYWVDFILSFYTGFTVT----------HDST- ----------------LLN------------------IKVFLEF---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVH------P ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >218.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MN-----------KITQ---AI---------VFLS------------- ---LAGPGIV------------GNILVFMRYVYTSALG---T-----EKRPIDL-ILIHL -------ALSNLIIICSTGVTDIV------------TVFYFRNFLGDIGCKMMVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-IWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-PSRHIIKWLF LSLMSLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLHSSRFA-- ---NNSPPEIRATWSVLILMAFFLF---FYWVDFILSFYTGFTVT----------HDST- ----------------LLN------------------IKVFLEF---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVH------P ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >218.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MN-----------KITQ---AI---------VFLS------------- ---LAGPGVV------------GNILVFMRYVYTSALG---T-----EKRPIDL-ILIHL -------ALSNLIIICSTGVTDIV------------TVFYFRNFLGDIGCKMMVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-IWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-PSRHIIKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLHSSRFA-- ---NNSPPEIRATWSVLILMAFFLF---FYWVDFILSFYTGFTVT----------HDST- ----------------LLN------------------IKVFLEF---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVH------P ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >218-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MN-----------KITQ---AI---------VFLS------------- ---LAGPGIV------------GNILVFMRYVYTSALG---T-----EKRPIDL-ILIHL -------ALSNLIIICSTGVTDIV------------TVFYFRNFLGDIGCKMMVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-IWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-PSRHIIKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLHSSRFA-- ---NNSPPEIRATWSVLILMAFFLF---FYWVDFILSFYTGFTVT----------HDST- ----------------LLN------------------IKVFLEF---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVH------P ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >218.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MMVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-IWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-PSRHIIKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLHSSRFA-- ---NNSPPEIRATWSVLILMAFFLF---FYWVDFILSFYTGFTVT----------HDST- ----------------LLN------------------IKVFLEF---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVH------P ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >218-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MN-----------KITQ---AI---------VFLS------------- ---LAGTGIV------------GNILVFMRYVYTSALG---T-----EKRPIDL-ILIHL -------AFSNLIIICSTGVTDIV------------TVFYFRNFLGDIGCKTMVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWS-KLKPQTS------WQVLPFL LLF---------WIVNILISSNLLSYIKSGSGSNRSVA-ATFIAHCYML-PSRHIIKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLHSSRFA-- ---NNSPPEIRATWSVLILMACFLF---FYWIDFILSFYTGFTVT----------HDST- ----------------LLN------------------IKVFLEF---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVH------P ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >201-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------M- ---ARGLSICTTCLLSVV-------QAVTISLRTT-IWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKAGSGLNRSVV-AMYIGHCYML-QSRHIIKWLF LSLMTLRDIIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLQSSRSA-- ---NSSPPEIRATWSVLILMVCFLF---FYWVDFIISFYTGFTVA----------HDSI- ----------------LLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVC------V ----P-NALHPH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >201-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKWN---------NITL---GI---------VFLS------------- ---LAGPGIL------------GNILVFVRYVHNSALE---T-----EKKPVDL-ILIHL -------AFSNMIIICSTGIRDLA------------TVFYFRNFLGDFGCKAAVYLARM- ---ARGLSICTTCLLSVL-------QAVTISPRTT-LWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKAGSGLNGSVA-AMYIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHKR----VLYLHSSRSA-- ---NNSPPEIRATWSVLILMTCFLF---FYWVDFIISFYTGFTVS----------HDSI- ----------------VLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVR------V ----P-NALHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >201-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKWD---------NITL---AI---------VFLS------------- ---LAGPGIV------------GNILVFVRYVHNSALG---T-----EKKPVDL-ILIHL -------AFSNLIIICSTGIKDLA------------AVFSFRNFLGDIGCKAAVYLARM- ---ARGLSICTTCLLSVL-------QAVTISPRTT-IWT-KLKPQTS------FQVLPFL LLF---------WIVSVLISSNLLSYIKAGSGLNRSIV-ATYIGHCYML-QSRHIIKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLYSSRSA-- ---NNSPPEIRATWSVLILMACFLF---FYWVDFIISFYTGFTVA----------HDSI- ----------------LLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVR------V ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >201-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NITL---TI---------VFLS------------- ---LAGPGIV------------GNILVFVRYVHNSALG---T-----EKKPLDL-ILIHL -------AFSNLIIICSTGIRDLA------------TVFSFRNFLGDIGCKAAVYLARM- ---ARGLSICTTCLLSVL-------QAVTISPRTT-IWT-KLKPQTS------FQVLPFL LLF---------WIVNVLISSNLLSYIKAGSGLNRSVV-ATYIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLHSSRSA-- ---NNSPPEIRATWSVLILMACFLF---FYWVDFIISFYTGFTVA----------HDSI- ----------------LLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVH------V ----P-NVLRAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >198-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWS---------NVIH---TI---------IFLS------------- ---LIGPGIM------------GNILMFARLGFTSALE---T-----EKKPIDL-ILIHL -------VFSNMIIICTTGLKELA------------TVFYFRNFLGDIGCKTTVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-FWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKAGSSLNRSVA-IMYIGHCYML-PSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLHSSRSA-- ---NNSPPEIRATWSVLILMACFLF---FYWVDFILSFYTGFTVT----------HDSL- ----------------SLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------NVR------V ----P-NILHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >198.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWS---------NVIH---TI---------IFLS------------- ---LTVPGIM------------GNILMFARLGYTSALE---T-----EKKPIDL-ILIHL -------VFSNMVIICTTGLKELA------------TVFYFRSFLGDIGCKTTVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-FWT-KFKPQTS------CQVLPFL LLF---------WIVNVLISS-------------------------------RHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHKR----VLYLYSSRFA-- ---KNSPPEIRATWSILILMACFLF---FYWVDFILSFYTGFTVT----------HDSI- ----------------SLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------NVR------V ----P-NTLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >198.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWS---------NVIH---TI---------IFLS------------- ---LTVPGIM------------GNILMFARLGYTSALE---T-----EKKPIDL-ILIHL -------VFSNMVIICTTGLKELA------------TVFYFRSFLGDIGCKTTVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-FWT-KFKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKGGSSLNRSVA-IMYIGHCYML-PSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHKR----VLYLYSSRFA-- ---KNSPPEIRATWSILILMACFLF---FYWVDFILSFYTGFTVT----------HDSI- ----------------SLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------NVR------V ----P-NTLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >198.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWS---------NVIH---TI---------IFLS------------- ---LIGPGIM------------GNILMFARLGYTSALE---T-----EKKPIDV-ILIHL -------VFSNMIIICTTGLKELA------------TVFYFRSFLGDIGCKTTVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-FWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKGGSSLNRSVA-IMYIGHCYML-PSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHKR----VLYLYSSRFA-- ---NNSPPEIRATWSILILMACFLF---FYWVDFILSFYTGFTVT----------HDSI- ----------------SLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------NVR------V ----P-NTLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >198.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWS---------NVIH---TI---------IFLS------------- ---LIGPGIM------------GNILMFARLGYTSALE---T-----EKKPIDL-ILIHL -------VFSNMIIICTTGLKELA------------TVFYFRSFLGDIGCKTTVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-FWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKGGSSLNRSVA-IMYIGHCYML-PSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHKR----VLYLYSSRFA-- ---NNSPPEIRATWSILILMACFLF---FYWVDFILSFYTGFTVT----------HDSI- ----------------SLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------NVR------V ----P-NTLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >198.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------M- ---ARGLSICTTCLLSVV-------QAVTISPRTT-FWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKGGSSLNRSVA-IMYIGHCYML-PSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHKR----VLYLYSSRFA-- ---NNSPPEIRATWSILILMACFLF---FYWVDFILSFYTGFTVT----------HDSI- ----------------SLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------NVR------V ----P-NTLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >198-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWS---------NVIH---TI---------IFLS------------- ---LIGPGIM------------GNILMFARLGYTSALE---T-----EKKPIDL-ILIHL -------VFSNMIIICTTGLKELA------------TVFYFRSFLGDIGCKTTVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-FWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKAGSSLNRSVA-ATFIGHCYML-QSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLYNSRFA-- ---NNSPPEIRATWSVLILMACFLF---FYWVDFIISFYTGFTVA----------HDSI- ----------------SLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------NVR------V ----P-NTLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >198.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------M------------GS------------------------------------ ---------NRHIPICPQSHRPLAH--------NSCASSYVKKIIDQI-C-----LALMT SPVSRGLSICTTCLLSVV-------QAVTISPRTT-FWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLSYIKGGSSLNRSVA-IMYIGHCYML-PSRHIIKWFF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYNHHKR----VLYLYSSRFA-- ---NNSPPEIRATWSILILMACFLF---FYWVDFILSFYTGFTVT----------HDSI- ----------------SLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------NVR------V ----P-NTLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >215-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIV------------GNMLIFIRHIYMPALR---T-----EKKPVDI-IIINL -------AFSNMITICTTGIKDIA------------TVFYFRNFLGDIGCKAVVFLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTS-LWT-KLKPQTA------CQVIPFI LVF---------WIFNGLISSNLLSYIKGGSSLNRSVA-STFIGHCYML-QSRHIIKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLHSSRST-- ---NNSPPEIRATWSVLTLMTCFLF---FYWVDFILSFYHGFTVT----------HESI- ----------------LLN------------------IKVFLEL---------------- ---G--YV-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------YIH------Y ----P-NVLHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >215-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIV------------GNMLIFIRHIYMPALG---T-----EKKPVDL-IVIHL -------AFSNMITICTTGIKDIA------------TVFYFRNFLGDIGCKAVVFLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTS-LWT-KLKPQTA------CQIIPFI LVF---------WIFNGLISSNLLSYIKGGSSLNRSVA-ATFIGHCYML-QSRHTIKWIF LSLMTLRDVIFQ-----------SLMG-WSSGSMALNLYKHHKR----VLYLYSSRFA-- ---NNSPPEIRATWSVLILMTCFLL---FYWADFILSFYHGFTVT----------HESI- ----------------LLN------------------IKVFLEL---------------- ---G--YV-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------YIH------S ----P-NVFHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >215-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIV------------GNMLIFIRHIYMPALG---T-----EKKPVDL-IVIHL -------AFSNMITICTTGIKDIA------------TVFYFRNFLGDIGCKAVVFLARM- ---ARGLSICTTCLLSVV-------QAITISPRTS-LWT-KLKPQTA------CQIIPFI LVF---------WIFNGLISSNLLSYIKGGSSLNRSVA-ATFIGHCYML-QSRHTIKWIF LSLMTLRDVIFQ-----------SLMG-WSSGSMALNLYKHHKR----VLYLYSSRFA-- ---NNSPPEIRATWSVLILMTCFLL---FYWADFILSFYHGFTVT----------HESI- ----------------LLN------------------IKVFLEL---------------- ---G--YV-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------YIH------P ----P-NVFHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >215-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIV------------GNMLIFIRHIYMPALG---T-----EKKPVDL-IVIHL -------AFSNMITICTTGIKDIA------------TVFYFRNFLGDIGCKAVVFLARM- ---TRGLSICTTCLLSVV-------QAVTISPRTS-LWT-KLKPQTA------CQIIPFI LVF---------WIFNGLISSNLLSYIKGGSSLNRSVA-ATFIGHCYML-QSRHTIKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALNLYKHHKR----VLYLYSSRFA-- ---NNSPPEIRATWSVLILMTCFLL---FYWADFILSFYHGFTVT----------HESI- ----------------LLN------------------IKVFLEL---------------- ---G--YV-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------YIH------S ----P-NVFHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >215-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIH---TI---------IFLS------------- ---LTGPGIV------------GNMLIFIRHIYMSALG---T-----EKKPVDL-IVIHL -------AFSNMITICTTGIKDIA------------TVFYFRNFLGDIGCKAVVFLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTS-LWT-KLKPQTA------CQIIPFI LVF---------WIFNGLISSNLLSYIKGGSSLNRSVA-AIFIGHCYML-QSRHTIKWLF LFLMTLRDVIFQ-----------SLMG-WSSGSMALNLYKHHKR----VLYLYSSRFA-- ---NNSPPEIRATWSVLILMTCFLL---FYWADFILSFYHGFTVT----------HESI- ----------------LLN------------------IKVFLEL---------------- ---G--YV-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------YIH------S ----P-NVFHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >246-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKWN---------NIIQ---AI---------VFIS------------- ---LTGPGTV------------GNILVFMRHVYTSALG---I-----AKRPVDL-IIIHL -------AFSNLIIICNTGVRDVA------------TVFYFRNFLGDIGCKTVIYLARM- ---ARGLSICTTCLLSVV-------QDVTINPRTT-LWT-KLKPQTS------CQVLPFL LLF---------WIVNVLISSNLLCYIKAGGGLNRSIA-ATFIGHCYML-PSRH-IKWLF LSLMTLRDIIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLYNSRSA-- ---NSSPPEIRATWSVLILMACFLF---FYWVDFIISFYTGSTVT----------RNFT- ----------------LLN------------------IKIFLEL---------------- ---G--YA-----------------------S-F--S---P--------------FV--- --------L-------------------------------ISR-------DVH------V ----P-NVSHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >246-x ------------------------------------------------M----------- ------------------------------------------------------------ -----------------------------------------------------CFFKKNF PSI------KQKMKWN---------NIIQ---AI---------VFLS------------- ---LTGPGTV------------GNILVFMRHVYTSALG---I-----AKKPVDL-IIIHL -------AFSNLIIIYSTGVRDVA------------TVFYFRNFLGDIGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWT-KLKPQTS------SQVLPFL LLF---------WIVNVLISSNLLCYIKAGGGLNRSIA-AAFIGHCYML-PSRH-IKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLYNSRFA-- ---NNSPPEIRATWSVLILMTCFLF---FYWVDFILSFYTGFTVT----------RNFT- ----------------LLN------------------IKTFLEL---------------- ---G--YA-----------------------S-F--S---P--------------YV--- --------L-------------------------------ISR-------DVR------V ----P-NVSHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >246-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKWN---------NIIQ---AI---------VFLS------------- ---LTGPGTV------------GNILVFMRHVYTSALG---I-----AKKPVDL-IIIHL -------AFSNLIIIYSTGVRDVA------------TVFYFRNFLGDIGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWT-KLKPQTS------SQVLPFL LLF---------WIVNVLISSNLLCYIKAGGGLNRSIA-AAFIGHCYML-PSRH-IKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLYNSKFA-- ---NNSLPEIRATWSVLILMTCFLF---FYWVDFIISFYTGFTVT----------RNFT- ----------------LLN------------------IKILLEL---------------- ---G--YA-----------------------S-F--S---P--------------FV--- --------L-------------------------------ISR-------DVR------V ----P-NVSHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >246-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKWN---------NIIQ---TI---------VFLS------------- ---LTGPGTV------------GNILVFMRHVYTSALG---I-----AKKPVDL-IIIHL -------AFSNLIIICSTGVRDVA------------TVFYFRNFLGDIGCKTVVYLARM- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWT-KLKPQTS------SQILPFL LLF---------WIVNVLISSNLLCYIKAGGGLNRSIA-AAFIGHCYML-PSRH-IKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKH----VLYLYSSKFA-- ---NNSLLEIRATWSVLILMTCFLLLGRFHY----------------------------- ----------------------------------------FLLH---------------- ---R--FH-----------------------S-D--S---K--------------FY--- --------F-------------------------------IKY----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >194-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------MSPRTT-IWK-KAKPQTS------RQVLTYV FLF---------WILNILTSSNLLYYITAGSGMNRSGV-TGYIGYCYML-PSKHIVKWLF LLLMAVRDLVFQ-----------SLMG-WSSGYISFHLYKHHKR----VLYLHSCRFV-- ---NSFSPEIRAAQSVVILMSCFLF---FYWADFIFSLYTGSMVS----------HDSI- ----------------ILN------------------IKTCLVL---------------- ---G--YA-----------------------V-L--S---P--------------FI--- --------L-------------------------------MNR-------DVP------V ----A-KS---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >194-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIQ---TI---------VFLS------------- ---LTGPGIV------------GNILMFVRLVYTSAFR---T-----EKKPVNL-ILIHL -------AFSNLIILCSTGIRDIA------------TVFYFRNFLGDIGCKAVVYLARM- ---ARGLSICTTCLLSTV-------QAVTISPRTT-IWK-KAKPQTS------RQVLTYV FLF---------WILNILTSSNLLYYITAGSGMNRSGV-TGYIGHCYML-PSKHTVKWLF LLLMAVRDLVFQ-----------SLMG-WSSGYISFHLYKHHKR----VLYLHSCRFV-- ---NTFSPEIRAAQSVVILMSCFLF---FYWADFIFSLYTGSMVS----------HDSI- ----------------ILN------------------TKTCLVL---------------- ---G--YA-----------------------V-L--S---P--------------FI--- --------L-------------------------------MNR-------DVP------V ----A-KS---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >194-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIQ---TM---------VFLS------------- ---LTGPGIV------------GNILMFVRLVYTSAFR---T-----EKKTVNL-ILIHL -------AFSNLIILCSTGIRDIA------------TVFYFRNFLGDIGCKAVVYLARM- ---ARGLSICTTCLLSTV-------QAVTMSPRTT-IWK-KAKPQTS------RQVLTYV FLF---------WILNILTSSNLLYYITAGSGMNRSGV-TGYIGYCYML-PSKHTVKWLF LLLMAVRDLVFQ-----------SLMG-WSSGYISFHLYKHHKR----VLYLHSCRFV-- ---NTFSPEIRAAQSVVILMSCFLF---FYWADFIFSLYTGSMVS----------HDSI- ----------------ILN------------------IKTCLVL---------------- ---G--YA-----------------------V-L--S---P--------------FI--- --------L-------------------------------MNR-------DVP------V ----A-KS---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >194-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIQ---TI---------VFLS------------- ---LTGPGIV------------GNILMFVRLVYTSAFR---T-----EKKTVNL-ILIHL -------AFSNLIILCSTGIRDIA------------TVFYFRNFLGDIGCKAVVYLARM- ---ARGLSICTTCLLSTV-------QAVTMSPRTT-IWK-KAKPQTS------RQVLTYV FLF---------WILNILTSSNLLYYITAGSGMNRSGV-TGYIGYCYML-PSKHTVKWLF LLLMAVRDLVFQ-----------SLMG-WSSGYISFHLYKHHKR----VLYLHSCRFV-- ---NTFSPEIRAAQSVVILMSCFLF---FYWADFIFSLYTGSMVN----------HDSI- ----------------ILN------------------IKTCLVL---------------- ---G--YA-----------------------V-L--S---P--------------FI--- --------L-------------------------------MNR-------DVP------V ----A-KS---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >194-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWN---------NIIQ---TI---------VFLS------------- ---LTGPGIV------------GNILMFVRLVYTSAFR---T-----EKKPVNL-ILIHL -------AFSNLIILCSTGIRDIA------------TVFYFRNFLGDIGCKAVVYLARM- ---ARGLSICTTCLLSAV-------QAVTMSPRTT-IWK-KAKPQTS------RQVLTYV FLF---------WILNILTSSNLLYYITAGSSMNRSGV-TGYIGYCYML-PSKHTVKWLF LLLMAVRDLVFQ-----------SLMG-WSSGYISFHLYKHHKC----VLYLHSCRFV-- ---NTFSPEIRAAQSVVILMSCFLF---FYWADFIFSLYIGSMVS----------HDSI- ----------------ILN------------------IKTCLEL---------------- ---G--YA-----------------------V-L--S---P--------------FI--- --------L-------------------------------MNR-------DVP------V ----A-KSYSFH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >194-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNWS---------NIVQ---TI---------VFLS------------- ---LTGPGIV------------GNILMLVRLVYTSAFR---T-----EKKPVNL-ILIHL -------AFSNMIIICSTGIRDIA------------TVFYFRNFLGDIGCKAVVYLARL- ---ARGLSICTTCLLSMV-------QAVTMSPRTT-IWK-KAKPQTS------WQVLTYV FLF---------WILNILTSSNLLYYITAGSGMNRSGV-TGYIGYCYML-PSRHIVKWLF LLLMAVRDLVFQ-----------SLMG-WSSGYISFRLYKHHKR----VLYLHSCRFV-- ---NSFSPEIRAAQSVVILMSCFLF---FYWADFTFSLYTGYMVS----------HDSI- ----------------ILN------------------IKTCLVL---------------- ---G--YA-----------------------V-L--S---P--------------FI--- --------L-------------------------------MNR-------DVP------V ----A-KS---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >216-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWS---------DLFQ---GI---------IFIS------------- ---LTGFGVL------------GNIILFVRHVYTFIMG---S-----ENKNIDV-IFIHL -------AFVNTIIIYCIGVRNIA------------TIFYIRNFLSDVGCKTIVYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLK----------LHVLAFL LLF---------WIFNSLISSNLLYYITAGSSMNRSEI-GMFTGYCYML-PSKHTVKWLF LSFMALRDVIFQ-----------SLMG-WSSGSMALHLYKHHVR----VLYLHSSRSA-- ---NNSRPEIRATQRVLTLMACFLF---FYWADFIFSLYIGSTVK----------NDIT- ----------------IPN------------------MKALLVL---------------- ---S--YA-----------------------G-L--S---P--------------FI--- --------L-------------------------------IIW-------DVH------I ----A-KICSVS------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >216.1-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MFT-----------------SLAFSGFF LVL------TMKIIWS---------DLVQ---GI---------IFIS------------- ---LTGFGVL------------GNFILFVRHVYTFIMG---S-----ENKNIDV-IFIHL -------AFVNTIIIYCIGVRNIA------------TVFYIRNFLSDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLKPQTA------WHILAFL LLF---------WIFNSLISSNLLHYITADSSMNRSEI-GMFTGYCYML-PSKPTVKWLF LSFMALRDVIFQ-----------SLMG-WSSGSMVLHLYKHHVR----VLYLHSYRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYWADFIFSLYIGSTVK----------NDFT- ----------------IPN------------------MKALLVL---------------- ---S--YA-----------------------G-L--S---P--------------FI--- --------L-------------------------------IIW-------DVH------I ----A-KICSVS------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >216-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWS---------DLVQ---GI---------IFIS------------- ---LTGFGVL------------GNFILFVRHVYTFIMG---S-----ENKNIDV-IFIHL -------AFVNTIIIYCIGVRNIA------------TVFYIRNFLSDVGCKTIVYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLK----------QHILAFL FLF---------WIFNSLISSNLLHYITAGSSMNRSEI-GMFTGYCYML-PSKPTVKWLF LSFMALRDVIFQ-----------SLMG-WSSGSMVLHLYKHHVR----VLYLHSSRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYWTDFIFSLYIGSTVK----------NDFT- ----------------IPN------------------MKALLVL---------------- ---S--YA-----------------------G-L--S---P--------------FI--- --------L-------------------------------IIW-------DVH------I ----A-KICSVS------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >216.1-z ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MFT-----------------SLAFSGFF LVL------TMKIIWS---------DLIQ---GI---------IFIS------------- ---LTGFGVL------------GNFILFVRHVYTFIMG---S-----ENKNIDV-IFIHL -------AFVNTIIIYCIGVRNIA------------TVFYIRNFLSDVGCKTIVYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLK----------LHVHAFL FLF---------WIFNSLISSNLLHYITAGSSMNRSEI-GMFTGYCYML-PSKPTVKWLF LSFMALRDVIFQ-----------SLMG-WSSGSMALHLYKHHVR----VLYLHSSRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYWADFIFSLYIGFTVK----------NDFT- ----------------IPN------------------MKALLVL---------------- ---S--YA-----------------------G-L--S---P--------------FI--- --------L-------------------------------IIW-------DVH------I ----A-KICSVS------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >216.2-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MFT-----------------SLAFSGFF LVL------TMKIIWS---------DLVQ---GI---------IFIS------------- ---LTGFGVL------------GNFILFVRHVYTFIMG---S-----ENKNIDV-IFIHL -------AFVNTIIIYCIGVRNIA------------TVFYIRNFLSDVGCKTIIYLERV- ---ARGLPICTTCLLSMV-------QAVTISPRTT-LWR-KLKPQTA------WHILAFL LLF---------WIFNSLISSNLLHYITADSSMNRSEI-GMFTGYCYML-PSKPTVKWLF LSFMALRDVIFQ-----------SLMG-WSSGSMVLHLYKHHVR----VLYLHSYRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYWADFIFSLYIGSTVK----------NDFT- ----------------IPK------------------YESIVST---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >216.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWK---------DLIQ---RV---------IFIS------------- ---LTGIGVL------------GNIILFVKHVHTFIMG---R-----ENKNIDV-ILIHL -------AFVNIIIIYCIGVRTIA------------MIFYIRNFLDDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLK----------LHVHAFL FLF---------WIFNSLISSNLLHYITAGSSMNRSEI-GMFTGYCYML-PSKPTVKWLF LSFMALRDVIFQ-----------SLMG-WSSGSMALHLYKHHVR----VLYLHSSRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYWADFIFSLYIGFTVK----------NDFT- ----------------IPN------------------MKALLVL---------------- ---S--YA-----------------------G-L--S---P--------------FI--- --------L-------------------------------IIW-------DVH------I ----A-KICSVS------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202/216-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWS---------DLIQ---KI---------IFIS------------- ---LIGLGVL------------GNIILFVRHVYTFIMG---P-----ENKNIDV-MLIHL -------AFVNTIIIYCIGVRDIA------------TIFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLKPQTA------WHILAVL LLF---------WIFNSLISSNLLHYITPGSSMNRSEI-GMFTGYCYML-PSKPTVKWLF LSFMALRDVIFQ-----------SLMG-WSSGSMALHLYKHHVH----VLYLHSSRSA-- ---NNSRPEIRATQRVLTLMTCFL------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >245-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIQ---SI---------IFLS------------- ---LTGLGVL------------GNIILFVRHLYTFIIG---P-----DKKNLDV-IIIHL -------AFVNTIIIYCIGVRDIA------------TSFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLKPQTA------GHILVFL LLF---------WIFNSLISSNLLHYITPGSSMNRSEI-GMFTGYCYML-PSKPTVKWLF LSFMALRDVIFQ-----------SLMG-WSSGSLALHLYKHHVR----VLYLHSSRSA-- ---NNSRPEIRATQRVLTLMACFLF---FYWADFIFSLYIGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIK-------DAR------V ----S-KPCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >245.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIQ---SI---------IFLS------------- ---LTGLGVL------------GNIILFVRHLYTFIIG---P-----DKKKLDV-IIIHL -------AFVNTIIIYCIGVRDIA------------TIFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLKPQTA------WHILAFL LLF---------WIFNSLISSNLLHYITPGSSMNRSEI-GKFTGYCYML-PSKPTVKWLF LSFMALRDVIFQ-----------SLMG-WSSGSLALHLYKHHVR----VLYLHSSRSA-- ---NNSRPEIRATQRVLTLMACFLF---FYWADLIFSLYIGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIK-------DAR------V ----S-KPCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >245.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIQ---SI---------IFLS------------- ---LTGLGVL------------GNIILFVRHLYTFIIG---P-----DKKKLDV-IIIHL -------AFVNTIIIYCIGVRDIA------------TIFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLKPQTA------WHILAFL LLF---------WIFNSLISSNLLHYITAGSSMNRSEV-GMFTGYCYML-PSRNIVKWLF LSFMAFRDVIFQ-----------SLMG-WSSGSMALHLYKHH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202/216-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWK---------DLIQ---RV---------IFIS------------- ---LTGIGVL------------GNIILFVKHVHTFIMG---R-----ENKNIDV-ILIHL -------AFVNIIIIYCIEVRTIA------------MIFYIRNFLDDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTA------WHVIAFL LLF---------WIFNSLISSNLLHYITAGSSMNRSEI-GIFTGYCYML-PSKPTVKWLF LSFMALRDVIFQ-----------SLMG-WSSGSLALHLYKHHVR----VLYLHSSRSA-- ---NNSRPEIRATQRVLTLMACFLF---FYWADLIFSLYIGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIK-------DAR------V ----S-KPCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >223.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWS---------DLIQ---KI---------IFIS------------- ---LIGLGVL------------GNIILFVRHLYTFIMG---P-----ENKNIDV-ILIHL -------AFVNTIIIYCIGVRDIA------------TSFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTIISRTT-LWR-KLKPQTA------WHVIAFL LLF---------WIFNSLISSNLLHYITVGSSMNSSEV-GMFTGYCYML-PSRHTVKWLF LSLMTLRDVIFQ-----------GLMG-WSSGSMALHLYKHHKR----VLYLHRSRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >223-m ----------------------------------------------MSME---------- -QRTEGPRIK---------AGICKQKNLC-IY---------------IIHCSFHGRKQKT HRH---------------------E---LDHAYF-------------------LVFLRFF LAL------AMKIIWS---------DLIQ---KI---------IFIS------------- ---LIGLGVL------------GNIILFVRHLYTFIMG---P-----ENKNIDV-ILIHL -------AFVNTIIIYCIGVRDIA------------TIFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLKPQTA------WHVIAFL LLF---------WIFNSLISSNLLHYITVGSSMNSSEV-GMFTGYCYML-PSRHTVKWLF LSLMTLRDVIFQ-----------GLMG-WSSGSMALHLYKHHKR----VLYLYSSRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---N--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------ITG-------NVH------D ----A-KPCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >223-z ------------------------------------------------ME---------- -PRTEGPRIK---------AGICKQKNLC-TY---------------IIHCSFHGRNQKT HRH---------------------E---LDHAYF-------------------LVFLRFF LAL------AMKIIWS---------DLIQ---RI---------IFIS------------- ---LIGLGVL------------GNIILFVRHLYTFIMG---P-----ENKNIDV-ILIHL -------AFVNTIIIYCIGVRDIA------------TIFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLKPQTA------WHVIAFL LLF---------WIFNSLISSNLLHYITVGSSMNSSEV-GMFTGYCYML-PSRHTVKWLF LSLMTLRDVIFQ-----------GLMG-WSSGSMALHLYKHHKR----VLYLHSSRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYWADFIFSLYTGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---N--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------ITG-------NVH------D ----A-KPCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >223.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------MV-------QAVTIISRTT-LWR-KLKPQTA------WHVIAFL LLF---------WIFNSLISSNLLHYITVGSSMNSSEV-GMFTGYCYML-PSRHTVKWLF LSLMTLRDVIFQ-----------GLMG-WSSGSMALHLYKHHKR----VLYLHRSRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---N--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------ITG-------NVH------S ----A-KPCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWK---------DLIE---RI---------IFIS------------- ---LTGIGVL------------GNIILFVKHVYTFIMG---R-----ENKNIDV-ILIHL -------AFVNTVIIYCIGIRTIA------------MIFYIRNFLDDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LCR-KLKPQTL------WHVLGFL LLF---------WIFNSLISSNLLHYITAGSSMNRSVV-GMFTGYCYIL-PSRNTVKWMF ISLMAVRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLHSSRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVA----------NDFT- ----------------IPS------------------MKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIF-------DVH------I ----A-KTCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWK---------DLIQ---RV---------IFIS------------- ---LTGIGAL------------GNIILFVKHVHTFIMG---R-----ENKNIDI-ILIYL -------AFVNIIIIYCIGVRTIA------------MIFYIRNFLDDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTP------WHVLAFL FLF---------WIFNSLISSNLLHYITAGSSMNRSVV-GMFTGYCYIL-PSRNTVKWMF ISLMAVRDVIFQ-----------GLMG-WSSGSMALHLYKHHKR----VLYLHSSRSA-- ---DNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVA----------NDFT- ----------------IPS------------------MKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIF-------DVH------I ----A-KTCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWK---------DLIQ---RV---------IFIS------------- ---LTGIGVL------------GNIILFVKHVHTFIMG---R-----ENKNIDV-ILIHL -------AFVNIIIIYCIGVRTIA------------MIFYIRNFLDDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTP------WHVLAFL LLF---------WMFNSLISSNLLHYITAGSSMNRSVV-GMVTGYCYIL-PSRNTVKWMF ISLMAVRDVIFQ-----------GLMG-WSSGSMALHLYKHHKR----VLYLHSSRSA-- ---DNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVA----------NDFT- ----------------IPS------------------MKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIF-------DVH------I ----A-KTCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202.1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWK---------DLIQ---RV---------IFIS------------- ---LTGIGVL------------GNIILFVKHVHTFIMG---R-----ENKNIDV-ILIHL -------AFVNIIIIYCIEVRTIA------------MIFYIRNFLDDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTP------WHVLVFL LLF---------WIFNSLISSNLLHYITAGSSMNRSVV-GMFTGYCYIL-PSRNTVKWMF ISLMAVRDVIFQ-----------GLMG-WSSGSMALHLYKHHKR----VLYLHSSRSA-- ---DNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVA----------NDFT- ----------------IPS------------------MKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIF-------DVH------I ----A-KTCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >193.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIE---GT---------IFLS------------- ---LIGLGVL------------GNKILFVRHLYAVIMG---P-----EKKIIDV-IFIHL -------AFVNTIIIYCIGVRNIA------------TSFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTINPRTT-LWR-KLKPQTT------WHVLAFL LLF---------WIFNSLISSNLLHYITAGSSMNRSVA-GMFTGYCYML-PSRHTVKWLF LSFMALRDVIFQ-----------GLMG-CSSGSMSLRLYKHHVR----VLYLHSSRSA-- ---DNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------ITG-------DVH------I ----A-KPCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >193.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIE---GT---------IFLS------------- ---LIGLGVL------------GNKILFVRHLYAVIMG---P-----EKKIIDV-IFIHL -------AFVNTIIIYCIGVRNIA------------TSFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTINPRTT-LWR-KLKPQTT------WHVLAFL LLF---------WIFNSLISSNLLHYITAGSSMNRSVA-GMFTGYCYML-PSRHTVKWLF LSFMALRDVIFQ-----------GLMG-CSSGSMSLRLYKHHVR----VLYLHSSRSA-- ---DNSRPEIRATQRVLTLMTCFLF---FYWADFIFSLYTGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FI--- --------L-------------------------------IIR-------DIC------V ----P-KPCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >193-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MSCLL-----------------PCVSEKVF LVL------SMKMIWS---------DLIE---GT---------IFLS------------- ---LIGLGVL------------GNKILFVRHLYAVIMG---P-----ENKIIDV-ILIHL -------AFVNTIIIYSIGVRNIA------------TSFYIRNFLGNVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTA------WHVLAFL LLF---------WIFNSLISSNLLHYITAGSSMNKSVV-GMFTGYCYML-PSRHTVKWLF LSFMALRDVIFQ-----------GLMG-CSSGSMSLRLYKHHVR----VLYLYSSGSA-- ---NNSRPEIRATQRVLTLMICFLF---FYLADFIFSLYTGSTVT----------RDST- ----------------ILN------------------IKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FI--- --------L-------------------------------IIK-------DIC------V ----P-KTCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >193-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MSCLL-----------------PCVSEKVF LVL------SMKMIWS---------DLIE---GT---------IFLS------------- ---LVGLGVL------------GNKILFVRHLYAVIMG---P-----ENKIIDV-ILIHL -------AFVNTIIIYCIGVRNIA------------TVFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTT------WHVLVFL ILF---------WIFNSLISSNLLHYITAGSSMNRSVV-GMFTGYCYML-PSRHTVKWLF LSFMALRDVIFQ-----------GLMG-CSSGSMSLRLYKHHVR----VLYLYSSGSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVT----------RDST- ----------------ILN------------------IKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FI--- --------L-------------------------------IIK-------DIC------V ----P-KTCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >193-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIE---GT---------IFLS------------- ---LIGLGVL------------GNKILFVRHLYAVIMG---P-----ENKIIDV-ILIHL -------AFVNTIIIYCIGVRDIA------------TFFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTINPRTT-LWR-KLKPQTT------WHVLVFL ILF---------WIFNSLISSNLLHYITAGRSMNRSVV-GMFTGYCYML-PSRHTVKWLF LSFMALRDVIFQ-----------GLMG-CSSGSMSLRLYKHHVR----VLYLYSSGSA-- ---NNSRPEIRATQRVLTLMTCFL------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >193.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIK---GT---------IFLS------------- ---LIGLGVL------------GNKILFVRHLYAVIMG---P-----ENKNIDV-ILIHL -------AFVNTIIIYCIGVRDIA------------TIFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLKPQTT------WHVLVFL ILF---------WIFNSLISSNLLHYITAGRSMNRSVV-GMFTGYCYML-PSRHTVKWLF LFFMALRDVIFQ-----------GLMG-CSSGSMSLRLYKHHVR----VLYLYSSGSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYLADFILSLYTGSTVT----------RDST- ----------------ILN------------------IKAFLVL---------------- ---C--YA-----------------------G-L--S---P--------------FI--- --------L-------------------------------IIK-------DIC------V ----P-KTCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >193.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIK---GT---------IFLS------------- ---LIGLGVL------------GNKILFVRHLYAVIMG---P-----ENKNIDV-ILIHL -------AFVNTIIIYCIGVRDIA------------TIFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KLKPQTT------WHVLVFL ILF---------WIFNSLISSNLLHYITAGRSMNRSVV-GMFTGYCYML-PSRHTVKWLF LFFMALRDVIFQ-----------GLMG-CSSGSMSLRLYKHHVR----VLYLYSSGSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVA----------NDFT- ----------------MPS------------------MKAFLVL---------------- ---S--YA-----------------------G-L--S---S--------------FV--- --------L-------------------------------IIF-------DVH------I ----A-KTCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >193-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIE---GT---------VFLS------------- ---LIGLGVL------------GNKILFVRQLYAVIMG---P-----ENKIVDV-ILIHL -------AFVNTIIIYCIGVRNIA------------TSFYIRNFLGDVGCKIIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTA------WHVLAFL FLF---------WIFNSLISSNLLHYITAGSSMNRSVV-GMFTGYCYML-PSRNIVKWLF LSLMTLRDVIFQ-----------GLMG-CSSGSMALRLYKHHVH----VLYLYSSRSA-- ---NNSRPEIRATQRVLTLMTCFLF---FYLADFIFSVYIGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIR-------DIC------A ----R-KSCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >204-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIA---GT---------IFLS------------- ---LILLGFL------------GNNILIVRHLYVVIIG---P-----EKKIIDI-ILIHL -------AFVNTIIIYCIGIRNIA------------TSFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTP------WHILAFL LLF---------WIFNSLISSNLLHYITAGSSINRSVV-GMFTVYCYML-PSRNTVKWLF LSFMAFRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLHSSRSA-- ---DNSRPEIRATQRVLTLMTCFLF---FYWADFIFSLYTGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FI--- --------L-------------------------------IIR-------DIC------V ----P-KPCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >204.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MSCLL-----------------PCVSEKAF LVL------SMKMIWS---------DLIA---GT---------IFLS------------- ---LILLGVL------------GNNMLFVRHLYVVIIG---P-----EKKIIDV-ILVHL -------AFVNTIIIYCIGVRNIA------------TSFYIRNFLGDVGCKIIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KFKPQTA------WHVLAFL LLF---------WIFNSLISSNLLHYITAGSSMNRSEV-GMFTVYCYML-PSRNIVKWLF LSFMAFRDVIFQ-----------SLMG-WSSGSMALHLYKHNKR----VLYLHSSRSA-- ---NNARPEIRATQRVLTLMTCFLF---FYLADFIFSLYIGSTVT----------HDST- ----------------ILY------------------IKAFLV----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >204.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MSCLL-----------------PCVSEKAF LVL------SMKMIWS---------DLIA---GT---------IFLS------------- ---LILLGVL------------GNNMLFVRHLYVVIIG---P-----EKKIIDV-ILVHL -------AFVNTIIIYCIGVRNIA------------TSFYIRNFLGDVGCKIIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTA------WHVLAFL LLF---------WIFNSLISSNLLHYITAGSSMNRSEV-GMFTVYCYML-PSRNIVKWLF LSFMAFRDVIFQ-----------SLMG-WSSGSMALHLYKHNKR----VLYLHSSRSA-- ---NNARPEIRATQRVLTLMTCFLF---FYLADFIFSLYIGSTVT----------HDST- ----------------ILY------------------IKAFLVL---------------- ---S--YV-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIW-------DIC------V ----P-NLCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >204-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKMIWS---------DLIA---GT---------IFLS------------- ---LILLGVL------------GNNMLFVRHLYVVIIG---P-----EKKIIDV-ILVHL -------AFVNTIIIYCIGVRNIA------------TSFYIRNFLGDVGCKIIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KFKPQTA------WHILAFL LLF---------WIFNTLISSNLLHYITAGSSMNSSEV-GMFTVYCYML-PSRNIVKWLF LSFMAFRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLHSSRSA-- ---NNARPEIRATQRVLTLMTCFLF---FYLADFIFSLYIGSTVT----------HDST- ----------------ILY------------------IKAFLVL---------------- ---S--YV-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIW-------DIC------V ----P-NLCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >245-p ---------------------------------------------MVLMSNCQH-HLCVS GSKKKWHKKK---------MRYYKQGSLS-IF---------------IRHYSFH-RKQKS HRH---------------------E---LHHVYFL------------------VFLKRFF LVL------GNKMIWS---------DLIQ---SM---------IFLS------------- ---LTGLGVL------------GNNILFVRHLYTFIIG---P-----DKKNLDV-IVIHL -------AFVNTIIIYCIGVRNIV------------TIFYTRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSMV-------QAVTISPRTT-LWR-KFKPQTA------WHVLAFL LFF---------WIFNSLISSNLLHYITAGNSMNGSEV-AMFTGYCYML-PSKHTVKWLF LSLMALRDVIFQ-----------GLMS-WSSGSMALHLYKHHVR----VLYLHSSRSA-- ---NNSRPEIRATQIVLALMACFLL---FYWADFIFSFYTGSTVT----------HDST- ----------------ILN------------------IKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIK-------DAC------V ----L-KPCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKINWN---------DLIQ---KV---------IFIS------------- ---LTGFGVL------------GNIILFVRHVYTFIMG---P-----ENKNIDV-ILIHL -------AFVNTIIICCIGVRTIA------------MSFYIRNFLDDVGCKTIIYVERV- ---ARGLSICSTCLLSMV-------QAVTISPRTI-LWR-KLKPQTA------WPVLAFL LLF---------WIFNSLISSNLLHYITLGISMNRSVV-GMFTGYCYML-PSRNIVKWLF LSLMTLRDVIFQ-----------GLMG-CSSGSMALRLYKHHVH----VLYLYSSRSA-- ---NNSRPEIRATQRVLTLMTCFLI---FHLADFIFSLYTGSTVT----------NDFT- ----------------IPN------------------MKALLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------ISW-------DVH------I ----A-KTCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKINWN---------DLIQ---KV---------IFIS------------- ---LTGFGVL------------GNIILFVRHVYTFIMG---P-----ENKNIDV-ILIHL -------AFVNTIIICCIGVRTIA------------MSFYIRNFLDDVGCKTIIYVERV- ---ARGLSICSTCLLSMV-------QAVTISPRTI-LWR-KLKPQTA------WPVLAFL LLF---------WIFNSLISSNLLHYITLGISMNRSVV-GMFTGYCYML-PSRNTVKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLHSSRST-- ---NNSPPEIRATWSVLTLMTCFLF---FYWVD--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal193-p ----------------------------------------------MSME---------- -PRTEGPRIK---------S---------------------------------------- ------------------------------------------------------------ -AL------VMKIIWS---------DHIQ---KI---------IFIS------------- ---LIGLGVI------------GNIILFVRHLYTFIMG---P-----ENKNIDV-ILIHL -------AFVNTIIIYCVGVRDIA------------TIFYIRNFLGDVGCKTVIYLERV- ---ARGLSICTTCLLSMV-------QAVTIRPRTT-LWR-KLKPQTS------WHVLAFL LLF---------WIFNSLISSNLLYYIKAGSSMNRSEV-AMFTGYCYML-PSRHTIKWLF LSLMTLRDVIFQ-----------SLMG-WSSGSMALHLYKHHKR----VLYLHSSRST-- ---NNSPPEIRATWSVLTLMTCFLF---FYWVD--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202.2-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWK---------DLIQ---RV---------IFIS------------- ---LTGIGVL------------GNIILFVKHVHTFIMG---R-----ENKNIDV-ILIHL -------AFVNIIIIYCIEVRTIA------------MIFYIRNFLDDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTA------WHVIAFL LLF---------WIFNSLISSNLLHYITVGSSMNSSEV-GMFTGYCYML-PSRHTVKWLF LSLMTLRDVIFQ-----------GLMG-WSSGSMALHLNKRHKHLHFTVLGLQTITSQ-- ---KSELPR-------------------------GFSLS--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >223-x ------------------------------------------------ME---------- -PRTEGPRIK---------AGICKQKNLC-TY---------------TIHCSFHGRNQKT HKH---------------------E---LDHAYF-------------------LVFLRFF LAL------AMKIIWS---------DLIQ---KI---------IFIS------------- ---LIGLGVL------------GNIILFVRHLYTFIMG---P-----ENKNIDV-ILIHL -------AFVNTIIIYCIGVRDIA------------TFFYIRNFLGDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LSR-KL------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MKIIWK---------DLIQ---RV---------IFIS------------- ---LTGIGAL------------GNIILFVKHVHTFIMG---R-----ENKNIDI-ILIYL -------AFVNIIIIYCIGVRTIA------------MIFYIRNFLDDVGCKTIIYLERV- ---ARGLSICTTCLLSVV-------QAVTISPRTT-LWR-KLKPQTP------WHVLAFL FLF---------WIFNSLISSNLLHYITAGSSMNRSVV-GMFTGYCYIL-PSRNTVKWMF ISLMAVRDVIFQV--S-----WAGVVGPWLSICISI-----------------TSVSS-- ---TFTVPGLQ-----------------------------------------------T- ----------------ILG------------------QKSELPR---------------- ---G--FS-------------------------L--S----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------MPCLLPCLSQKGFP------------SSEHEDNLEGPY------------ -------------------------------PK-----R-KLKPQTP------WHVLAFL FLF---------WIFNSLISSNLLHYITAGSSMNRSVV-GMFTGYCYIL-PSRNTVKWMF ISLMAVRDVIFQ-----------GLMG-WSSGSMALHLYKHHKR----VLYLHSSRSA-- ---DNSRPEIRATQRVLTLMTCFLF---FYLADFIFSLYTGSTVA----------NDFT- ----------------IPS------------------MKAFLVL---------------- ---S--YA-----------------------G-L--S---P--------------FV--- --------L-------------------------------IIF-------DVH------I ----A-KTCCVP------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >195-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIWS---------ELIQ---RV---------IFLS------------- ---LIGLGIL------------GNILIFVRHVHIFTMG---S-----EKKPIDL-IFTHL -------AFSNVIIIGTSGIRYVA------------TKLHFKNVLGVAGCKTLVYLGRV- ---ARGLSICTTCLLSMV-------QAVTISPRTS-FLR-KFRPQTI------WQVLPSL LLL---------CIFNVLISSNLLHHITVGSSLNRSRA-GAYYGYCYML-PSRYTVKWLF LSLMTLRDVIFQ-----------CLMG-WSSGYMALRLYKHHKR----VLYLHTSRLA-- ---NNASPEIRATWSVLILMTCFLL---YYFGDYILSFYIGSVLT----------LDSI- ----------------ILN------------------IRIFLVI---------------- ---G--CA-----------------------A-L--S---P--------------SV--- --------L-------------------------------LIK-------DFH------L ----I-SCWRTQWRG--------------EETTFYNN-PSR------------------- ------------------------------------------------------------ --------------------------------N--------------------------- ------------- >195-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MMIWS---------VLIQ---RV---------IFLS------------- ---LIGLGIL------------GNILIFVRHVLTFTMG---S-----EKKPIDL-IFTHL -------AFSNVIIIGTSGIRYVA------------TKLHFKNVLGVAGCKTLVYLGRV- ---ARGLSICTTCLLSMV-------QAVTISPRTS-FLR-KFRPQTI------WQVLPSL LLL---------CIFNVLISSNLLHHITVGSSLNTSRA-GVYYGYCYML-PSRYTVKWLF LSLMTLRDVIFQ-----------CLMG-WSSGYMALRLYKHHKC----VLYLHTSRLA-- ---NNASPEIRATWSVLILMTCFLL---YYFGDYILSFYIGSVLT----------LDSI- ----------------ILN------------------IRIFLVI---------------- ---G--YA-----------------------A-L--S---P--------------FV--- --------L-------------------------------LIK-------DFH------L ----I-SCWHTHWRV--------------KETTFYNN-PSS------------------- ------------------------------------------------------------ --------------------------------N--------------------------- ------------- >195-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIWS---------ELIQ---RV---------IFLS------------- ---LIGLGIL------------GNILIFVRHVLTFTMG---S-----EKKPIDLIIFTHL -------AFSNVIIIGTSGIRYVA------------TKLHFKNGLGIAGCKTLVYLGRV- ---ARRLSICTTCLLSMV-------QVVTISPRTS-FLR-KFRPQTI------WQVLPSL LLL---------CIFNVLISSNLLHHITVGSSLNRSRA-GVYYEYCYML-PSRYTVKWLF LRLMTLRDVIFQ-----------CLMG-WSSGYMALRLYKHHKC----VLYLHTSRLA-- ---NNASPEIRATWSVLILMTCFLL---YYFGDYILSFYIGSVLT----------LDSI- ----------------ILN------------------IRIFLVI---------------- ---G--YA-----------------------A-L--S---P--------------FV--- --------L-------------------------------LIK-------DFH------L ----I-SCWHTHWQV--------------EETTFYNN-PSS------------------- ------------------------------------------------------------ --------------------------------N--------------------------- ------------- >202.4-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MG---P-----ENKNTDI-IFVYL -------AFVNTTIIYCLGVRNTV------------TIFYIRNFLGDIACKTIVYLEMI- ---AHGLSMTSA------------------PPVSL-VWS-RLSPSVPGPHCGESSIHGMF LPFSS------SWILNSPISSNLLHYITAGSSMNSSET-GMFTGYCYML-ASSHTVKWLF LSLMALRDVIF---Q--------GLMG-WSSGSMALHLYKRHKHLHFTVLGLQTITSQ-- ---KSELPR-------------------------------GFSLS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >202.5-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MG---P-----ENKNTDI-IFVYL -------AFVNTTIIYCLGVRNTV------------TIFYIRNFLGDIACKTIVYLEMI- ---AHGLSMTSA------------------PPVSL-VWS-RLSPSVPGPHCGESSIHGMF LPFSS------SWILNSPISSNLLHYITAGSSMNSSET-GMFTGYCYML-ASSHTVKWLF LSLMALRDVIFPGSH--------GLEQ-WVHGSPSV------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >191-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KFIE---KM---------VFLF------------- ---MILVGTL------------GNMSVSVNYMLSWWRS---T-----GKKPIHL-ILVHL -------TFTNIILLLAKGLPKTV------------AAFGLRNFLDDIGCKVIVYLERV- ---ARGLSICTSSLLTVI-------QAIIVSPRAS-GWR-RLRPKSA------WHILPFL SFF---------WIFNSLISIHLVHFITS-TGLNISHL-KNSDNYCYFI-LPSQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTHPELRAAQSVLLLMLCFAL---FYWTDCAFSLIISISLV----------ENSL- ----------------IVN------------------IQECLTL---------------- ---A--YA-----------------------S-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----A-GCCSAQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >191-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MWKE-- ----------VKMVL----------KFIE---KM---------VFLF------------- ---MILVGTL------------GNMSVSVNYMFSWWRS---T-----GKKPIHL-ILIHL -------AFTNIILLLAKGLPKTI------------AAFGLRNFLDDIGCKVIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRPTSA------WHILPFL SFF---------WTFNSLISIHLIHSITS-TGLNISHL-KNSDNYCYFI-LPSQKIKWIV LLLMILRDAVFQ-----------GAMG-GASGYMVFLLHKYHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSISLV----------ENSL- ----------------IVN------------------IQECLTL---------------- ---A--YA-----------------------S-F--S---P--------------LV--- --------L-------------------------------IHR-------DGV------L ----A-GCCSAQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >191-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KFIE---KM---------VFLF------------- ---MILVGTL------------GNMSVSVNYMLSWWRS---T-----GKKPIHL-ILIHL -------AFTNIILLLAKGLPKTV------------AAFGLRNFLDDIGCKVIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRPTSA------WHILPFF SFF---------WTFNSLISIHLIHSITS-TGLNISHL-KNSDNYCYFI-LPSQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQQ----VLYLQNSKLL-- ---YRTPPELRVAQSVLLLMLCFVF---FYWTDCAFSLILSISLV----------ENSL- ----------------IVN------------------IQECLTL---------------- ---A--YA-----------------------S-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----A-GCCSAQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >191-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KFIE---KM---------VFLF------------- ---MILVGTL------------GNMSVSVNYMFIWGRS---T-----GKKPIHL-ILIHL -------AFTNIILLLAKGLPKTI------------AAFGLRNFLDDTGCKIIVYLERV- ---ARGLSICTSSLLAMV-------QAIIISPRGS-GWR-RLRPKSA------WHILPFL SFF---------WTFNSLISIHLIHSITS-TGLNTSHL-KNSDNYCYFI-LPSQKTKWIV LPLLVMRDAVFQ-----------GAMG-GASGYMVFLLHKHHQ----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >191-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIN---KVN-------KISLF------------- ---MTVVGTL------------GNMFVSVNYTFSYWGS---S-----EKKPIYL-TLIHL -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSFLTVV-------QAIIISPRAS-GWS-RLRPKSA------WHILPFL SFF---------WTFNSLISIHLIHSITS-TGLNISHL-KNRDNYCYFI-LPSQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSISLV----------ENSL- ----------------IVN------------------IQECLTL---------------- ---A--YA-----------------------S-F--S---P--------------LV--- --------L-------------------------------IHR-------DGV------L ----T-GCCSAQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >214-c -MHLPLPREHKKMLLYQLCYSDPCLAL-----------------LILSLK---------- ----------------------C----IF-I----------------------------- -----------------------------------------------------LHTRK-- ----------EEMIW----------KLIK---KI---------LFLF------------- ---MTMLGIL------------GNMSVSVNYMFCWWGS---P-----EKKSVHL-ILIHL -------TFTNIIILLTKGLQKTI------------VAFGLRNFLNNLGCKIIVYLERV- ---SHGLSLCTSSLLTVV-------QAIIISPRPS-GWR-RLRPKSV------WNILPFF LFF---------WIFNALISMNLINSITS-TRLNISQL-KSDDNYCYFM-LPSQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSLSSR----------DNTL- ----------------TVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ERWHVQSKK------------------L-----RNCLSF--------------- ICSTRK----------------------------KKLSVLQY------------------ ----------------CG------------------------------------------ ------------- >214.3-s -MHLPLPLEHKKMLLYQLCCSDPCLAL-----------------LMLSLK---------- ----------------------C----IF-I----------------------------- -----------------------------------------------------LHTRK-- ----------EEMIW----------KLIK---KI---------LFLF------------- ---MTMLGIL------------GNMFVSVNFMLSWWGS---P-----EKKSVHL-ILIHL -------AFTNIIILLTKGLQKTI------------VAFGLRNFLNNLGCKIIVYMERV- ---AHGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSV------WHILPFF LLF---------WILNALISMNLINSITS-IRLNISQL-KSDDNYCYFM-LPSQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLVLSLSSR----------DKTL- ----------------TVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----F-ECCHAQLKK------------------L-----RNCLSF--------------- ICSTRK----------------------------KKLSVLQH------------------ ----------------CG------------------------------------------ ------------- >214.1-s -MHLPLPLEHKKMLLYQLCCSDPCLAL-----------------LMLSLK---------- ----------------------C----IF-I----------------------------- -----------------------------------------------------LHTRK-- ----------EEMIW----------KLIK---KI---------LFLF------------- ---MTMLGIL------------GNMFVSVNFMLSWWGS---P-----EKKSVHL-ILIHL -------AFTNIIILLTKGLQKTI------------VAFGLRNFLNNLGCKIIVYMERV- ---AHGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSV------WHILPFF LLF---------WILNALISMNLINSITS-IRLNISQL-KSDDNYCYFM-LPSQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLVLSLSSR----------DKTL- ----------------TVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----F-ECCHAQLKK------------------L-----RNCLSF--------------- ICSTRK----------------------------KKLSVLQH------------------ ----------------CG------------------------------------------ ------------- >214-z -MHLPLPLEHKKMLLYQLCCSDPCLAL-----------------LMLSLK---------- ----------------------C----IF-I----------------------------- -----------------------------------------------------LHTRK-- ----------EEMIW----------KLIK---KI---------LFLF------------- ---MTMLGIL------------GNMFVSVNFMLSWWGS---P-----EKKSVHL-ILIHL -------AFTNIIILLTKGLQKTI------------VAFGLRNFLNNLGCKIIVYMERV- ---AHGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSV------WHILPFF LFF---------WILNALISMNLINSITS-TRLNISQL-KSDDNYCYFM-LPSQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYIVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWTDCAFSLVLSLSSR----------DKTL- ----------------TVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ERCHAQSKK------------------L-----RNCLSF--------------- ICSTRK----------------------------KKLSVLQH------------------ ----------------CG------------------------------------------ ------------- >214-m -MRLPLPLEHKKMLLYQLWCSDPCLAL-----------------LMLSLK---------- ----------------------C----IF-I----------------------------- -----------------------------------------------------LHTRK-- ----------EEMIW----------KLIK---KI---------LFLF------------- ---MTMLGIL------------GNMFVSVNFMLSWWGS---P-----EKKSVHL-ILIHL -------AFTNIIILLTKGLQKTI------------VAFGLRNFLNNLGCKIIVYMERV- ---AHGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSV------RHILPFF LFF---------WILNALISMNLINSITS-TRLNISQL-KSDDNYCYFM-LPSQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLVLSLSSR----------DKTL- ----------------TVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----F-ECCHAQLKK------------------L-----RNCLSF--------------- ICSTRK----------------------------KKLSVLQH------------------ ----------------CG------------------------------------------ ------------- >214-x -MHLPLPLEHKKMLLYQLCCSDPCLAL-----------------LMLSLK---------- ----------------------C----IF-I----------------------------- -----------------------------------------------------LHTRK-- ----------KEMIW----------KLIK---KI---------LFLF------------- ---MTMLGIL------------GNMFVSVNFMLSWWGS---P-----EKKSVHL-ILIHL -------AFTNIIILLTKGLQKTI------------VAFGLRNFLNNLGCKIIVYMERV- ---AHGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSV------WHILPFF LFF---------WILNALISMNLINSITS-TRLNISQL-KSDDNYCYFM-LPSQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYIVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIINISSR----------DTTL- ----------------MIN------------------TREFLTL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----N-KFWHAQWEK------------------L-----RKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >214.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MTMLGIL------------GNMFVSVNFMLSWWGS---P-----EKKSVHL-ILIHL -------AFTNIIILLTKGLQKTI------------VAFGLRNFLNNLGCKIIVYMERV- ---AHGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSV------WHILPFF LLF---------WILNALISMNLINSITS-IRLNISQL-KSDDNYCYFM-LPVRK----- ------------------------------------------------------------ -------------------------------SNGLFSLLWS------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >214-p -MPLPLPLEHKKTLLYQMCCSDPCLAL-----------------LMLFLK---------- ----------------------C----IF-I----------------------------- -----------------------------------------------------LHTRK-- ----------EEMIW----------TLIK---KI---------LFLF------------- ---MTVLGIL------------GNMSVSVNYMFSWWGG---P-----EKKLIHL-ILIHL -------AFTNIVILLTKGLQKTI------------VAFGMRNFLEDIGCEIIVYLERV- ---AHGLSLCTSSLLTVV-------QAIIISPRAS-GWK-RLRPKSA------WHILPFF VFF---------WVFNALISMNLINSITS-TRLNISQL-KSDDNYCYFM-LPSQKIKLIV LPLLVLRDAVFQ-----------GTMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFAF---FYWTDCAFSLVLSLSSR----------DNTL- ----------------TVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------NGF------L ----A-EYWHAQSKK------------------L-----RKCLAF--------------- ICSTRK----------------------------KKLSVLQY------------------ ----------------CG------------------------------------------ ------------- >199-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIL----------KLIK---KI---------LFLF------------- ---MTVLGIL------------GNMSVSVNYMFSWWGS---P-----EKKPVHL-ILIHL -------AFTNTVILLAKGLPKTI------------VAFGLSNFLDDSGCKIIVYLERV- ---AHGLSLCASSLLTVV-------QAIIISPRTS-GWR-MLRPKSA------WHILPFF LFF---------WLFSALISMNLIHSITS-TRLNISQF-KSDSNNCYFM-LPSQKIKGIV LPLMVLRDAIFQ-----------GAMG-GASGYMVFLLYKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSLSSR----------DNTL- ----------------MVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ERWHVQWEK------------------L-----RKCLLF--------------- ICSTRK----------------------------KKLSVLHY------------------ ----------------CG------------------------------------------ ------------- >199.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIL----------KLIK---KI---------LFLF------------- ---MTVLGIM------------GNMSVSVNYMFSCWGS---P-----EKKPVHL-ILIHL -------AFTNTVILLAKGLPKTI------------VAFGLRNFLDDSGCKIIVYLERV- ---AHGLSLCASSLLTVV-------QAIIISPRAS-GWR-MLRPKSA------WHILPFF LFF---------WLFSALINMNLINSITS-TRLNISQF-KTDSNNCYFM-LPSQKIKGIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLYKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMFCFVF---FYWTDCAFSLILSLSSK----------DNTL- ----------------MVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ERWHVQWEK------------------L-----RKCLLF--------------- ICSTRK----------------------------KKLSVLQY------------------ ----------------CG------------------------------------------ ------------- >199.2-m -MHPPLPLEHQKMLSCKMCCSDPCPAL-----------------LILSLK---------- ----------------------C----IC-I----------------------------- -----------------------------------------------------LHTRK-- ----------EEMIL----------KLIK---KI---------LFLF------------- ---MTVLGIM------------GNMSVSVNYMFSCWGS---P-----EKKPVHL-ILIHL -------AFTNTVILLAKGLPKTI------------VAFGLRNFLDDSGCKIIVYLERV- ---AHGLSLCASSLLTVV-------QAIIISPRAS-GWR-MLRPKSA------WHILPFF LFF---------WLFSALINMNLINSITS-TRLNISQF-KTDSNNCYFM-LPSQKIKGIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLYKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMFCFVF---FYWTDCAFSLILSLSSK----------DNTL- ----------------MVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ERWHVQWEK------------------L-----RKCLLF--------------- ICSTRK----------------------------KKLSVLQY------------------ ----------------CG------------------------------------------ ------------- >199.1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MA---------------------------------- ------------------------------------------------------------ -------SLCASSLLTVV-------QAIIISPRAS-GWR-MLRPKSA------WHILPFF LFF---------WLFSALINMNLINSITS-TRLNISQF-KTDSNNCYFM-LPSQKIKGIV LPLMVLRDAVFQ-----------SAMG-GASGYMVFLLYKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSLSSR----------DNTL- ----------------MVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ERWHVQWEK------------------L-----RKCLLF--------------- ICSTRK----------------------------KKLSVLQY------------------ ----------------CG------------------------------------------ ------------- >199-s -MHPPLPLEHQKMLSCKMCCSDPCLAL-----------------LTLSLK---------- ----------------------C----IC-I----------------------------- -----------------------------------------------------LHTRK-- ----------EEMIL----------KLIK---KI---------LFLF------------- ---MTVLGIM------------GNMSVSVNYMFSWWGG---A-----EKKPVHL-ILIHL -------AFTNTVILLAKGLPKTI------------VAFGLRNFLDDSGCKIIVYLERV- ---AHGLSLCASSLLTVV-------QAIIISPRAS-GWR-ILRPKSA------WHILPFF LFF---------WLFSALININLINSITS-TRLNISQF-KTDNNNCYFM-LPSQKIKGIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHHH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSLSSR----------DNTL- ----------------MVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ERWHVQWEK------------------L-----RKCLLF--------------- ICSTRK----------------------------KKLSVLQY------------------ ----------------CG------------------------------------------ ------------- >206/209.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIE---EI---------IFPS------------- ---MTVLGTL------------GNMSVSVNFMFSWWGS---P-----EKKPIHL-ILIHL -------AFTNIIILLTKGLPKTV------------VAFGLRNFLDAIGCKIIVYLGRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWS-RLRPKSA------WHILPFF SFF---------WILNAFISVNLIHSIRS-TGMNTSQ---NSDNYCYLT-SESQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----ILYLQTSKLL-- ---YRTPPELRAAQSVFLLMLCFVF---FYWIDCAFSLIFSLSSR----------DNTL- ----------------VAN------------------TEEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHK-------DGL------L ----V-ECWHAQWEK------------------L-----RKCHSH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206/209.3-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIK---EI---------TFLL------------- ---ITVIGTL------------GNVSVSVNYMFNWWRG---P-----EKKPIYL-ILIHL -------AFTNILILLTKGLPKTV------------AAFGLRNFLDDIGCKIIVYLTRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-KLKPKSA------WHILLFF LYF---------WILNGLISMNLIHSITS-TGLNISQL-KNSDNYCYFM-LESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCVFSVIISISSR----------DNTL- ----------------MAN------------------TGEFLTL---------------- ---G--YA-----------------------T-F--G---P--------------LV--- --------L-------------------------------IHK-------DGF------L ----V-ECWHAQWEK------------------L-----RKCHSH--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >206/209.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------MNLIHSITS-TGLNISQL-KNSDNYCYFM-LESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----ILYLQTSKLL-- ---YRTPPELRAAQSVFLLMLCFVF---FYWIDCAFSLIFSLSSR----------DNTL- ----------------VAN------------------TEEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHK-------DGL------L ----V-ECWHAQWEK------------------L-----RKCHSH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206/209.3-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIN---EI---------VFLF------------- ---ITVVGTL------------GNMSVSVNYMFNWWRG---P-----EKKPIHL-ILIHL -------AFTNILILLTKGLPKTI------------AAFGLRNFLDDIGCKTIVYLERV- ---ARGLSICTSSLLTVV-------QATIISPRAS-GWN-RLRPKYA------WHILLFF LYF---------WILNGLISMNLIHSITS-TGLNISQL-KNSDNYCYFM-LESQEIKWIV LPLMVLRDAVFQ-----------AAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDSAFSLILSLSSR----------DNTW- ----------------MVN------------------TQEFIIL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGF------L ----V-ECWHAQWEK------------------L-----RKYFSH--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >206-c -------------MHPG------------------------------------------- ------------------------------YKF--------------------------- -----------------------------------------------------FLTKK-- ----------REMVL----------KYIK---EI---------IFIF------------- ---ITVFGTL------------GNMYVSVNYMFSWWGN---P-----EKKSVHL-ILIHL -------AFTNILILLTKGLPKTV------------AAFGLRNFLDAIGCKIIVYLGRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-RWS-RLRPRST------WHILLFF LYF---------WILNALMSMNLIHSITS-AGLNISQL-KNSNNYCYLM-QESQEIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSIFLLMLCFVF---FYWIDCTYSLILSLSSR----------DNTL- ----------------MAN------------------TQEFLTL---------------- ---G--YA-----------------------T-F--G---P--------------LV--- --------L-------------------------------IHK-------DGL------L ----V-GCWHAQWEK------------------L-----RKCHFH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206-s --------MLLQNVLTGSMSRITEVFF-----------------KSL------------- ----------------------C----ILDTSF--------------------------- -----------------------------------------------------FLTRK-- ----------KEMVL----------KYIK---EI---------IFIF------------- ---ITVIGTL------------GNMSVSVNYMFSWWGN---P-----EKKSVHL-ILIHL -------AFTNIIILLTKGLPKIV------------AVFSLRNFLDDIGCKIIVYLGRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-RWS-RLRPRSA------WHILLFF LYF---------WVLNALMSMNLIHSITS-AGLNMSQL-KNSNNYCYLM-QESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLFLQNSKLL-- ---YRTPPELRAAQSIFLLMLCFVF---FYWTDCTFSLILSISSR----------DNTL- ----------------IAN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ECCHVKWEK------------------L-----RKCHSH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIK---EI---------IFIF------------- ---ITVIGTL------------GNMSVSVNYMFSWWGN---P-----EKKSVQL-ILIHL -------AFTNIIILLTKGLPKTV------------AAFGLRNFLDAIGCKIIVYLGRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-RWS-RLRPRSA------WHILLFF LYF---------WILNALMSMNLIHSITS-VGLNMSQL-KNSNNYCYLM-QESQEIKWIF LPLMVLRDALFQ-----------GAMG-GASGYMVFLLHKHHQH----VLFLQSSKLL-- ---YRTPPELRAAQSIFLLMLCFVF---FYWTDCTFSLILSLSSR----------DNTL- ----------------IAN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ECWHAQWEK------------------L-----RKCHSH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIK---EI---------IFTF------------- ---ITVIGTL------------GNMSVSVNYMFSCWGN---P-----EKKSVHL-ILIHL -------AFTNIIILLTKGLPKTV------------AAFGLRNFLDAIGCKIIVYLGRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-RWS-RLRPRSA------WHILLFF LYF---------WILNALMSMNLIHSITS-AGLNMSQL-KNSNNYCYLM-QESQEIKWIV LPLMILRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSLFSR----------DNTL- ----------------IAN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ECWYAQMEK------------------L-----RKCHSH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206-x --------MLLQNVLIGSMSRITEVFF-----------------ESL------------- ----------------------C----ILDTSF--------------------------- -----------------------------------------------------FLTRK-- ----------KEMVL----------KYIK---EI---------IFTF------------- ---ITVIGTL------------GNMSVSVNYMFSWWGN---P-----EKKSVHL-ILIHL -------AFTNIIILLTKGLPKTV------------AAFGLRNFLDAIGCKIIVYLGRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-RWS-RLRPRSA------WHILLFF LYF---------WILNALMSMNLIHSITS-VGLNMSQL-KNSNNYCYLM-QESQEIKWIV LPLMILRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSLFSR----------DNTL- ----------------IAN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ECWHA------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >209-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIK---EI---------IFTF------------- ---ITVVGTL------------GNTSVFVNYMFSWWGN---P-----EKKSVQL-ILIHL -------AFTNIIILLTKGLPKTV------------AAFGLRNFLDAIGCKIIVYLGRV- ---AHGLSICTSSLLTVV-------QAIIISPRAS-RWS-RLRPRSA------WHILLFF LYF---------WILNALMSMNLIHSITS-TDLNMSQR-KNSNNYCYLM-QENQEIEWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSNLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIFSLSSR----------DNTL- ----------------VAN------------------TEEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ECWHAQWEK------------------L-----RRCHSH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206/209.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIK---EI---------IFIF------------- ---ITVVGTL------------GNMSVSVNYMFSWWGN---S-----EKKSVHL-ILIHL -------AFTNIIILLTKGLPKTV------------AAFGLRNFPDAIGCKIIVYLGRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-RWS-RLRPRSA------WHILLFF LYF---------WILNALISMNLIHAITS-AGLNISQL-KNSNNYCYLM-LENQEVKWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQSSKLL-- ---YRTPPELRAAQSVFLLMLCFVF---FYWTDCAFSLILSLFSR----------DNRL- ----------------MAN------------------TQEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHK-------NGL------L ----V-GCWHAQWEK------------------L-----RKCYSH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206/209.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIK---EI---------IFIF------------- ---ITVVGTL------------GNMSVSVNYMFSWWGN---S-----EKKSVHL-ILIHL -------AFTNIIILLTKGLPKTV------------AAFGLRNFPDAIGCKIIVYLGRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-RWS-RLRPRSA------WHILLFF LYF---------WILNALISMNLIHAITS-AGLNISQL-KNSNNYCYLM-LENQEVKWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQSSKLL-- ---YRTPPELRAAQSVFLLMLCFVF---FYWTDCAFSLILSLFSR----------DNRL- ----------------MAN------------------TQEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHK-------NGL------L ----V-GCWHAQWEK------------------L-----RKCYSH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206/209-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIK---EI---------NFIF------------- ---ITVVGTL------------GNMSVSVNYMFSWWGN---P-----EKKSVHL-ILIHL -------AFTNIIILLTKGLPKTV------------AAFGLRNFPDAIGCKIIVYLGRV- ---ARGLSICTSSLLTVV-------QAIIISPRSS-RWS-RLKPRSA------WHILLFF LYF---------WILNALISMNLIHAITS-TGLNISQL-KNSNNYCYFM-LENQEVKWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVFLLMLCFVF---FYWTDCAFSIILSLFSR----------DNRL- ----------------MAN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ECWYAQMEK------------------L-----RKCHSH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206/209-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------MNLIHAITS-TGLNISQL-KNSNNYCYFM-LENQEVKWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVFLLMLCFVF---FYWTDFAFSLILSLFSR----------DNRL- ----------------MAN------------------TQEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ECWHAQWKK------------------L-----RKCHSH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >206/209.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KFIK---KI---------IFLF------------- ---ITVLGIL------------GNLLVSLNYMFSWCGG---S-----EKKLIHR-ILIHL -------VFTNILILLTKGLPKTI------------VAFGLRNFLDDIGCKIIVYLERV- ---GRGLSICTSSLLTVV-------QAIIISPRAS-GWN-RLRPKSA------WNILLFF LYF---------WIINALISMNLIHSITS-TGLNISQL-KKSDKYCYFM-LESQEIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSLSSR----------DNTL- ----------------MAN------------------TQEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHK-------DGL------L ----V-ECWHSQWEK------------------L-----RKCLSH--------------- L-------------------------------------NV-------------------- ------------------------------------------------------------ ------------- >206/209.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYTK---KI---------IFLS------------- ---TTVVGTL------------GNMSVSVNYMFNWWGS---P-----EKKPIHL-ILIHL -------AFTNILILLTNGLPKTI------------AAFGLRNFLDAIGCKIIVYLGRV- ---ARGLSISTSSLLTVV-------QAIIISPRAS-GWN-RLRPKSA------WNILLFF LYF---------WIINALISMNLIHSITS-TGLNISQL-KKSDKYCYFM-LESQEIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSLSSR----------DNTL- ----------------MAN------------------TQEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHK-------DGL------L ----V-ECWHSQWEK------------------L-----RKCLSH--------------- L-------------------------------------NV-------------------- ------------------------------------------------------------ ------------- >199/214-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIK---EI---------IFLF------------- ---MTVVGTL------------GNMSVSANYMFSWWGI---P-----EKKPIHI-ILIHL -------AFTNIIVLLTKGLQKTV------------AAFGLRNFLDDIGCKIIVYLTRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWS-RLRPKSA------WHILPFF SFF---------WILNAFISVNLIHSIRS-TGMNTSQ---NSDNYCYLT-SESQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSLSSR----------DNTL- ----------------TVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ERWHVQSKK------------------L-----RNCLSF--------------- ICSTRK----------------------------KKLSVLQY------------------ ----------------CG------------------------------------------ ------------- >220-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------MFSWWGS---P-----EKRPIHL-ILIHL -------TFTNIILLLAKGLQNTI------------IVFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSVLTVV-------QAIIISPRAS-GWR-RLRPKSA------WHILPFF SFF---------WILNAFISVNLIHSIRS-TGMNTSQ---NSDNYCYLT-SESQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >220-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---KT---------IFLF------------- ---MTMVGIL------------GNMSVSVHYMFSWWGS---P-----EKKPIHL-ILTHL -------TFTNIILLLAKGLQKTI------------IVFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSVLTVV-------QAIIISPRAS-GWR-RLRPKSA------WHILPFF SFF---------WILNAFISVNLIHSIRS-KGMNTSQH-KNSDDYCYLT-PESQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWTDCALSLFLSLSLG----------DSSL- ----------------MIN------------------IQGFLTL---------------- ---G--YA-----------------------I-F--S---P--------------FV--- --------L-------------------------------IQR-------DGL------I ----P-VCWHAQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >217-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---ET---------IFLF------------- ---MTMVGIL------------GNMSVSVNYMFSWWGS---P-----EKKPIHL-ILTHL -------SFTNIVLLLAKGLQKTI------------TVFGLRNFLDDIGCKIIVYLDRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWS-RLRPKSA------WHILPFF SFF---------WILNGLISMNLIHSITS-TGLNMSQL-SNSNNYCYFM-PESREIKWIV LPLMVLRDAVFQ-----------GAMG-GASGHMIFLLHKHHQH----VLYLQNSKLL-- ---YRTPP---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >217-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---ET---------IFLF------------- ---MTMVGIL------------GNMSVSVHYMFSWWGS---P-----EKKPIHL-ILTHL -------SFTNIILLLAKGLQKTI------------TVFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWS-RLRPKSA------WHILPFF SFF---------WILNGLISMNLIHSITS-TGLNMSQL-NNSKNYCYFM-PESREIKWIV LPLMVLRDAVFQ-----------GAMG-GASGHMIFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCALSLFLSLSLG----------DSSL- ----------------MIN------------------IQKVLTL---------------- ---G--YA-----------------------V-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----P-ACWHAQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >217.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---ET---------IFLF------------- ---MTMVGIL------------GNMSVSVNYMFSWWGS---P-----EKKPIHL-ILTHL -------SFTNIILLLAKGLQKTI------------TVFGLRNFLDDIGCKIIVYLDRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWS-RLRPKST------WHILPFF SFF---------WILNGLISMNLIQSITS-AGLNMSQL-SNSNNYCYFM-PESREIKWIV LPLMVLRDAVFQ-----------GAMG-GASGHIIFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWTDCALSLFLSLSLG----------DRSL- ----------------MIN------------------IQKVLTL---------------- ---G--YA-----------------------V-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------M ----P-ACWHAQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >217.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGL----------QFIK---ET---------IFLF------------- ---MTMVGIL------------GNMSVSVNYMFSWWGS---P-----EKKPIHL-ILTHL -------SFTNIILLLAKGLQKTI------------TVFGLRNFLDDIGCKIIVYLDRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWS-RLRPKST------WHILPFF SFF---------WILNGLISMNLIQSITS-AGLNMSQL-SNSNNYCYFM-PESREIKWIV LPLMVLRDAVFQ-----------GAMG-GASGHIIFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWTDCALSLFLSLSLG----------DRSL- ----------------MIN------------------IQKVLTL---------------- ---G--YA-----------------------V-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------M ----P-ACWHAQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >219.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---EI---------FFFF------------- ---MTMVGIL------------GNMSVSVHYMFSWWGS---P-----EKKPIHL-ILTHL -------TFTNIILLLAKGLQKTI------------TVFRLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSFLTVV-------QAIIISPRAS-GWS-RLRPKSA------WHVLPFF SFF---------WVLNASISVNLIHSIRS-IGMNTSQH-KNSDNYCYMT-LESQEMKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLFLSLSLG----------DYLL- ----------------MVS------------------IHESVTL---------------- ---V--YA-----------------------I-S--S---P--------------LL--- --------L-------------------------------IHR-------DGL------L ----T-ECCHSQWET------------------L-----RKFLSL--------------- L-------------------------------------YFQ------------------- ------------------------------------------------------------ ------------- >219.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---EI---------FFFF------------- ---MTMVGIL------------GNMSVSVHYMFSWWGS---P-----EKKPIHL-ILTHL -------SFTNIILLLAKGLQKTI------------TVFRLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSFLTVV-------QAIIISPRAS-GWS-RLRPKSA------WHVLPFF SFF---------WVLNASISVNLIHSIRS-IGMNTSQH-KNSDNYCYMT-LESQEMKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >219-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---EI---------FFFF------------- ---MTMVGIL------------GNMSVSVHYMFSWWGS---P-----EKKPIHL-ILTHL -------SFTNIILLLAKGLQKTI------------TVFRLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSFLTVV-------QAIIISPRAS-GWS-RLRPRSA------WHILPFL SFF---------WVLNASISVNLIHSIRS-IGMNTSQH-KNSDNYCYMT-LESQEMKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >219-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---EI---------FFFF------------- ---MTMVGIL------------GNMSVSVHYMFSWWGS---P-----EKKPIHL-ILTHL -------TFTNIILLLAKGLQKTI------------TVFRLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSFLTVV-------QAIIISPRAS-GWS-RLRPKSA------WHILPFF SFF---------WIFNGLISVNLIHSIRS-IGMNTSQH-KNSDNYCYMT-LESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQQ----VLYFQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLFLSLSLG----------DYLL- ----------------MVS------------------IHESVTL---------------- ---G--YA-----------------------V-S--S---P--------------LL--- --------L-------------------------------IHR-------DGL------L ----T-ECCHSQWET------------------L-----RNCLSL--------------- L-------------------------------------YFQ------------------- ------------------------------------------------------------ ------------- >189-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIN---KI---------IFLF------------- ---MTVVGIL------------GNMSVSANYMFSWWGS---P-----EKKPIHV-ILIHL -------AFINIIILLTKGLPKTV------------AAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWS-RLRPKST------WHILPFF SFF---------WILNGLISMNLIQSITS-AGLNMSQL-SNSNNYCYFM-PESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSIILSLSSR----------DNTL- ----------------MAN------------------TLEFVTL---------------- ---G--CA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ECWYVQMEK------------------L-----RKCLSH--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >189-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIN---KI---------IFLF------------- ---MTVVGTL------------GNMSVSANYMFSWWGS---P-----EKKPIHV-ILIHL -------AFTNIIILLTKGLPKTV------------AAFGLRNFLDDIGCKIIVYLTRV- ---ARGLSICTRSLLTVV-------QAIIISPRAS-GWR-RLRPKSA------RHILPFF SFF---------WILNGLISMSLIHSITG-TGFNISQL-KNSDNYCYFM-QESQEIKGIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWTDCAFSIILSLSSR----------DNTL- ----------------VAN------------------TLEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHK-------DGL------L ----V-ECWHAQMEK------------------L-----RKCLSH--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >200-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------MNLIHSITG-TGFNISQL-ENSDSYCYFM-QESQGIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLILSLSSR----------DKTL- ----------------MEN------------------TQEFLAL---------------- ---G--YA-----------------------S-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DCWHAQWEK------------------L-----RKCHFH--------------- L-------------------------------------NVQ------------------- ------------------------------------------------------------ ------------- >200.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLLQ----PMSSRKFLKPKAAT---------VFCNPFVRRIRMFVKAK WVRMRCMGFFSGLPLHEQCLHYGKHVVSVNYMFSWWGS---P-----EKKPIHL-ILTHL -------AFTNILILLTKGLQKTV------------AAFGLRNFLDDIGCKSIVYLERV- ---SRGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRTKSA------RHILPFL LFF---------WILNGLISMNLIHSITG-TGFNISQL-ENSDSYCYFM-LESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASSYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLILSLSSR----------DKTL- ----------------MVN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DCWHAQMEK------------------L-----RKCYSR--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >200.4-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------MFSWWGS---P-----EKKPIHL-ILTHL -------AFTNILILLTKGLQKTV------------AAFGLRNFLDDIGCKSIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRTKSA------RHILPFL LFF---------WILNGLISMNLIHSIIS-TGMNISQH-KNSDNYCYFM-QESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >200.5-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIL----------KYIK---EI---------IFPS------------- ---MTVLGTL------------GNMFVSVNYMFSWWGS---P-----EKKPIHL-ILTHL -------AFTNILILLTKGLQKTV------------AAFGLRNFLDDIGCKSIVYLERV- ---SRGLSICTSSLL-------------IISPRAS-GWR-RLRTKSA------RHILPFL LFF---------WILNGLISMNLIHSITG-TGFNISQL-ENSDSYCYFM-LESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASSYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLILSLSSR----------DKTL- ----------------MVN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DCWHAQMEK------------------L-----RKCYSR--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >200.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIL----------KYIK---EI---------IFPS------------- ---MTVLGTL------------GNMFVSVNYMFSWWGS---P-----EKKPIHL-ILTHL -------AFTNILILLTKGLQKTV------------AAFGLRNFLDDIGCKSIVYLERV- ---SRGLS---------------------ISPRAS-GWR-RLRTKSA------RHILPFL LFF---------WILNGLISMNLIHSITG-TGFNISQL-ENSDSYCYFM-LESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASSYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLILSLSSR----------DKTL- ----------------MVN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DCWHAQMEK------------------L-----RKCYSR--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >200.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIL----------KYIK---EI---------IFPS------------- ---MTVLGTL------------GNMFVSVNYMFSWWGS---P-----EKKPIHL-ILTHL -------AFTNILILLTKGLQKTV------------AAFGLRNFLDDIGCKSIVYLERV- ---SRGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRTKSA------RHILPFL LFF---------WILNGLISMNLIHSITG-TGFNISQL-ENSDSYCYFM-LESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASSYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLILSLSSR----------DKTL- ----------------MVN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DCWHAQMEK------------------L-----RKCYSR--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >200.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MFCE------------- ---LYVLGTL------------GNMFVFVNYMFSWWGS---P-----EKKPIHL-ILIHL -------AFTNIIILLTKGLQKTI------------AAFGLRNFLDDIGCKSIVYLERV- ---SRGLSICTSSLLTVV-------QAITISPRAS-GWR-RLRTKSA------WHILPFL LFF---------WILNGLISMNLIHSITG-TGFNISQL-ENRDSYCYFM-LESQEIKWIV LPLMVMRDAVFQ-----------SALG-GASGYMIFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFAF---FYWTDCAFSLILSLSSR----------DKTL- ----------------MVN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DWWHAQMEK------------------L-----RKCYSR--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >200.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIL----------KYIK---EI---------IFPS------------- ---MTVLGTL------------GNMFVFVNYMFSWWGS---P-----EKKPIHL-ILIHL -------AFTNIIILLTKGLQKTI------------AAFGLRNFLDDIGCKSIVYLERV- ---SRGLSICTSSLLTVV-------QAITISPRAS-GWR-RLRTKSA------WHILPFL LFF---------WILNGLISMNLIHSITG-TGFNISQL-ENRDSYCYFM-LESQEIKWIV LPLMVMRDAVFQ-----------SALG-GASGYMIFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFAF---FYWTDCAFSLILSLSSR----------DKTL- ----------------MVN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DWWHAQMEK------------------L-----RKCYSR--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >200.2-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MFCE------------- ---LYVLGTL------------GNMFVSVNYMFSCWRS---P-----EKKPIHL-ILIHL -------AFTNILILLTKGLQKTV------------AAFGLRNFLDDTGCKSIVYLERV- ---SRGLSICTSSLLTVV-------QAIIISPRAS-GWR-KLRPKSA------WHILPFL LFF---------WILNGLISRNLIHSITG-TGFNISQL-ENSDSYCYFM-LESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---CRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLILSLCSR----------DKTM- ----------------MVN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DCRHAQMEK------------------L-----RKCHSR--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >200.1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIL----------KYIK---EI---------IFPS------------- ---MTVLGTL------------GNMFVSVNYMFSCWRS---P-----EKKPIHL-ILIHL -------AFTNILILLTKGLQKTV------------AAFGLRNFLDDTGCKSIVYLERV- ---SRGLSICTSSLLTVV-------QAIIISPRAS-GWR-KLRPKSA------WHILPFL LFF---------WILNGLISRNLIHSITG-TGFNISQL-ENSDSYCYFM-LESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---CRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLILSLCSR----------DKTM- ----------------MVN------------------TQEFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DCRHAQMEK------------------L-----RKCHSR--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >247-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------MNLIHSIIS-TGMNISQH-KNSDNYCYFM-QESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQQ----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLISSLSSR----------DNAL- ----------------IVN------------------TLEFLSL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DFWHTQMEK------------------L-----RKCHSH--------------- L-------------------------------------FVQ------------------- ------------------------------------------------------------ ------------- >247-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIE---EI---------IFPS------------- ---MTVLGTL------------GNMSVSVNFMFSWWGS---P-----EKKPIHL-ILIHL -------AFTNIILLLTKGLPKAI------------ETFGIRNFLDDIGCKIIVYLGRV- ---ARGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKST------RHILPFL LFF---------WILNGLISMNLIHSIIS-TGMNISQH-KNSDNYCYFM-QESQEIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQQ----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLISSLSSR----------DNEL- ----------------MVN------------------TLEFLSL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DFSHAQMEK------------------L-----RKCHSH--------------- S-------------------------------------FVQ------------------- ------------------------------------------------------------ ------------- >247.1-x ----MTAFQTQENATVQICCSYTYLAL-----------------KRLSSEC----V---- ----------------------C----IL-YTS--------------------------- -----------------------------------------------------FSPRK-- ----------EDMVL----------KYIE---EI---------IFPS------------- ---MTVLGTL------------GNMSVSVNFMLSWWGS---P-----EKKPIHL-ILIHL -------AFTNIILLLTKGLPKAI------------ETFGIRNFLDDIGCKIIVYLGRV- ---ARGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSA------QHILPFL LFF---------WILNGLISMNLIHSIIS-TGMNISQH-KNSDNYCYFM-QESQEIKWIV LPLMVLRDALFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWTDCAFSLISSLSSR----------DNTL- ----------------MVN------------------TLEFLSL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DFWHAQMEK------------------L-----RKCHSH--------------- L-------------------------------------FVQ------------------- ------------------------------------------------------------ ------------- >247.2-z ----MTAFQTQENATVQICCSYTYLTL-----------------KRLSSEC----V---- ----------------------C----IL-YTS--------------------------- -----------------------------------------------------FSPRK-- ----------EEMIL----------KYIE---EI---------IFPS------------- ---MTVLGTL------------GNMSVSVNFMLSWWGS---P-----EKKPIHL-ILIHL -------AFTNIILFLTKGLPKAI------------ETFGIRNFLDDIGCKIIVYLGRV- ---ARGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSA------QHILPFL LFF---------WILNGLISMNLIHSIIS-TGMNISQH-KNSDNYCYFM-QESQEIKWIV LPLMVLRDALFQ-----------GAMG-GASGYMIFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWTDCAFSLISSLSSR----------DNTL- ----------------MVN------------------TLEFLSL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DFWHAQMEK------------------L-----RKCHSH--------------- L-------------------------------------FVQ------------------- ------------------------------------------------------------ ------------- >247.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIL----------KYIK---EI---------IFPS------------- ---MTVLGTL------------GNMSVSVNFMLSWWGS---P-----EKKPIHL-ILIHL -------AFTNIILFLTKGLPKAI------------ETFGIRNFLDDIGCKIIVYLGRV- ---ARGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSA------QHILPFL LFF---------WILNGLISMNLIHSIIS-TGMNISQH-KNSDNYCYFM-QESQEIKWIV LPLMVLRDALFQ-----------GAMG-GASGYMIFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWTDCAFSLISSLSSR----------DNTL- ----------------MVN------------------TLEFLSL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-DFWHAQMEK------------------L-----RKCHSH--------------- L-------------------------------------FVQ------------------- ------------------------------------------------------------ ------------- >247.2-x ----MTAFQTQENATVQICCSYTYLAL-----------------KRLSSEC----V---- ----------------------C----IL-YTS--------------------------- -----------------------------------------------------FSPRK-- ----------EDMVL----------KYIE---EI---------IFPS------------- ---MTVLGTL------------GNMSVSVNFMLSWWGS---P-----EKKPIHL-ILIHL -------AFTNIILLLTKGLPKAI------------ETFGIRNFLDDIGCKIIVYLGRV- ---ARGLSLCTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSA------QHILPFL LFF---------WILNGLISMNLIHSIIS-TGMNISQH-KNSDNYCYFM-QESQEIKWIV LPLMVLRDALFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLVLSLSSR----------DKTL- ----------------TVN------------------PRELLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ERCHAQSKK------------------L-----RNCLSF--------------- ICSTRK----------------------------KKLSVLQH------------------ ----------------CG------------------------------------------ ------------- >217/219/220-z ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMVL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------AAFGLRNFLDDIGCKTIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRTKSA------WHILPFL LFF---------WILNGLISMNLIHSITS-TGLNMSQL-SNSNSYCYFM-PESREIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCALSLFLSLSLG----------DSFL- ----------------MIN------------------IQKVLTL---------------- ---G--YA-----------------------V-F--S---P--------------LV--- --------L-------------------------------IQR-------DGL------L ----P-ACWHVQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >205-c ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EEMVL----------NYIN---KI---------ISLF------------- ---MTVFGTL------------GNMSVSVNYMFSWWGS---P-----EKKSIHL-ILIHM -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRGS-GWR-KLKPKSA------WHILPFF SFF---------WILNALISTNLIHSIKS-ASMNISQH-INDENYCYFT-LQNQDIKWIF LILMVLRDTVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLLNSNLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIINISSR----------DTSL- ----------------MIN------------------TREFLTL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----S-KIWHAHWEK------------------L-----RKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >210.1-c ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EEMVL----------NYIN---KI---------ISLF------------- ---MTVFGTL------------GNMSVSVNYMFSWWGS---P-----EKKSIHL-ILIHM -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRGS-GWR-KLKPKSA------WHILPFF SFF---------WILNALISTNLIHSIKS-ASLNISQH-INDDNYCYFM-LENEKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLLNSNLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIISISAR----------ENSL- ----------------MVN------------------TRDFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-KFWHAQWEK------------------L-----RKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >210-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MFL----------NYIN---KI---------ISLF------------- ---MTVFGTL------------GNMSVSVNYMFSWWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRGS-GWR-KLKPKSA------WHILPFF SFF---------WILNALISTNLIHSIKS-ASINISQR-INDDNYCYFM-LENEKIKWVV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQQ----VLYLLNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLIISISSR----------DNNL- ----------------MLN------------------TREFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-KFWHAQWEK------------------L-----RKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >205.1-s ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMFL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------LVFGLRNFLDDIGCKIIVYLERM- ---ARGLSICTSSLLTVL-------QAIIISPRAS-GWR-RLKPKSA------WHILPFF SFF---------WILNALISTNLIHFIRS-TSLNISQH-INDEKYCYFT-LQNQDIKWIF LILMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRAPPEMRAAQSVLLLMLCFVF---FYWTDCAFSLIISISSS----------DTTL- ----------------MIN------------------TREFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----N-KFWHAQWEK------------------L-----RKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >205.3-s ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMVL----------NYIN---KI---------IFLF------------- ---MTVFGTL------------GNMSVSVNYMFSWWGS---P-----EKKPIYL-ILIHL -------AFTNILILLAKGLPKTI------------LVFGLRNFLDDIGCKIIVYLERM- ---ARGLSICTSSLLTVL-------QAIIISPRAS-GWR-RLKPKSA------WHILPFF SFF---------WILNALISTNLIHFIRS-TSLNISQH-INDEKYCYFT-LQNQDIKWIF LILMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRAPPEMRAAQSVLLLMLCFVF---FYWTDCAFSLIISISSS----------DTTL- ----------------MIN------------------TREFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----N-KFWHAQWEK------------------L-----RKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >205-x ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMVL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRGS-GWR-KLKPKSA------WHILPFF SFF---------WILNALISTNLIHSIRS-TSLNISQH-INDENYCYFT-LQNQDIKWIF LIFMVLRDTVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLLNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIINISSR----------DTTL- ----------------MIN------------------TREFLTL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----N-KFWHAQWEK------------------L-----RKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >205-m ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EEMVL----------NYIN---KI---------IFPF------------- ---MTMFGTL------------GNMSVSVNYMFSCWGS---P-----EKKPIYL-ILIHL -------AFTNILILLAKGLPKTI------------LVFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLKPKSA------WHILPFF SFF---------WILNGLISTNLIHFIRS-TSLNISQH-INDENYCYFT-LQNQDIKWIF LILMVLRDTVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLLNSNLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSIIINISSR----------DTTL- ----------------MIN------------------TREFLTL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----N-KFWHAQWEK------------------L-----RKYL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >210-x ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMVL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRGS-GWR-KLKPKSA------WHILPFF SFF---------WILNALISTNLIYSIKS-ASMNISQR-INDDNYCYFM-LENKKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIISISSR----------DNNL- ----------------MLN------------------TREFLTL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-KFWHAQWEK------------------L-----RKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >210-z ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMVL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRGS-GWR-KLRPKSA------WHILPFF SFF---------WILNALISTNLIYSIKS-ASMNISQR-INDDNYCYFM-LENEKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIISISSR----------DNNL- ----------------MLN------------------TLEFLTL---------------- ---G--CA-----------------------T-F--R---P--------------FV--- --------L-------------------------------IHR-------DGL------Q ----V-KFWHAQWEK------------------L-----RKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >210.2-c ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EEMVL----------NYIN---KI---------ISLF------------- ---MTVFGTL------------GNMSVSVNYMFSWWGS---P-----EKKPIHI-ILIHL -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVI-------QAIIVSPRAS-GWR-RLRPKSA------WHILPFL SFF---------WIFNSLISIHLVHFITS-TGLNISHL-KNSDNYCYFI-LPSQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLLNSNLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIISISAR----------ENSL- ----------------MVN------------------TRDFLAL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-KFWHAQWEK------------------L-----RKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >205.2-s ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMFL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------LVFGLRNFLDDIGCKIIVYLERM- ---ARGLSICTSSLLTVL-------QAIIISPRAS-GWR-RLKPKSA------WHILPFF SFF---------WILNALISTNLIHFIRS-TSLNISQH-INDEKYCYFT-LQNQDIKWIF LILMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSIILSLSSR----------DNTL- ----------------MAN------------------TLEFVTL---------------- ---G--CA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----V-ECWYVQMEK------------------L-----RKCLSH--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >203.4-s ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMFL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------AAFGLRNFLDDIGCKTIVYLERV- ---SRGLSICTSSLLTVV-------QAIIISPRTS-GWR-RLRPKSA------WHILPFF SFF---------WILNALISTNLIHSIRS-TSLNISQH-INDENYCYFM-LENQKMKLVV LHLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVFLLMLCFVF---FYWTDCALSLIISISAR----------ENSL- ----------------MVN------------------TRNFLAL---------------- ---G--YA-----------------------T-F--C---P--------------FV--- --------L-------------------------------IHR-------DGL------W ----L-NFGMLSGRN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >203-m ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMVL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIYL-ILIHM -------AFTNILILLAKGLPKTI------------AAFGLRNFLDDIGCKTIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRTS-GWR-RLRPKSA------WHILPFF SFF---------WILNALISTNLIHSIRS-TSLNISQH-INDENYCYFM-LENQKIKLIV LHLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVFLLMLCFVF---FYWTDCALSLIISISAR----------ENSL- ----------------MVN------------------TRNFLAL---------------- ---G--YA-----------------------T-F--C---P--------------FV--- --------L-------------------------------IHR-------DGL------W ----L-NFGMLCGRN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >203-x ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMVL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------AAFGLRNFLDDIGCKTIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRTS-GWR-RLRPKSA------WHILPFF SFF---------WILNALISTNLIHSIRS-TSLNISQH-INDENYCYFM-LEKQKIKLIV LHLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVFLLMLCFVF---FYWTDCALSLIISISAR----------ENSL- ----------------MVN------------------TRNFLAL---------------- ---G--YA-----------------------T-F--C---P--------------FV--- --------L-------------------------------IHR-------DGL------W ----L-NFGMLSGRN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >203.3-s ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMFL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------LVFGLRNFLDDIGCKIIVYLERM- ---ARGLSICTSSLLTVL-------QAIIISPRAS-GWR-RLKPKSA------WHILPFF SFF---------WILNALISTNLIHSIRS-TSLNISQH-INDENYCYFM-LENQKMKLVV LHLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVFLLMLCFVF---FYWTDCALSLIISISAR----------ENSL- ----------------MVN------------------TRNFLAL---------------- ---G--YA-----------------------T-F--C---P--------------FV--- --------L-------------------------------IHR-------DGL------W ----L-NFGMLSGRN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >203.1-s ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMFL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLAICTSSLLTVV-------QAIIISPRGS-GWR-KLKPKSA------WHILPFF SFF---------WILNALISTNLIHSIK-------------------------------- -------------------------------------MNKYE--------YITTYK---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >203.2-s ------------------------------------------------------------ ------------------------------MQV--------------------------- -----------------------------------------------------FLPRK-- ----------EKMFL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------AAFGLRNFLDDIGCKTIVYLERV- ---SRGLSICTSSLLTVV-------QAIIISPRTS-GWR-RLRPKSA------WHILPFF SFF---------WILNALISTNLIHSIK-------------------------------- -------------------------------------MNKYE--------YITTYK---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal203-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MFL----------KYIK---DI---------IFLF------------- ---MTVVGTL------------GNMSVSVNYTFSCWGS---P-----EKKPIHL-ILIHM -------AFTNILILLAKGLPKTI------------AAFGLRNFLDDIGCKIIVYMERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWS-RLRPKST------WHILPFL SFF---------WILNALISMNLIYSITS-TGLNISQH-VNDDNYCYFT-LESQKIKWIV LPLMVLRDTVFQ-----------GAMG-GASGYMAFLLQKHHQH----VLYLLNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIISISAR----------NNTF- ----------------MIN------------------TRNFLTL---------------- ---G--YA-----------------------T-F--S---P--------------FM--- --------L-------------------------------IHR-------DGL------L ----V-KFWHAQWE---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >213-c -----------------MCSSDPYLAL-----------------LMLSLK---------- ----------------------C----IC-I----------------------------- -----------------------------------------------------LYTRK-- ----------EEMIL----------KILK---EI---------TFLV------------- ---MTVLGIL------------GNMSVSVNYMFSWWGS---P-----EKKPIHL-ILTHL -------SFTNIVLLLAKGLQKTI------------TVFGLRNFLDDIGCKIIVYLDRV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-MLRPKSA------WHILLFF LFF---------WILNALISVSLIHSTTN-TRLNVSQL-KSDDNYCYFM-LPIQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHK-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >213.2-p -----------------MYSSDPYLAL-----------------LMLSLK---------- ----------------------C----IC------------------------------- ----------------------------------------------------ILYTRK-- ----------EEMTL----------KILK---EI---------TFLV------------- ---MTVLGIL------------GNMSVSVNYMFSWWGS---H-----EKKPIHL-ILIHL -------IFTNIIILLVKGLPKTI------------AAFGLRNFLDDIGCKIIVYMERL- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSA------WHILPFF SFF---------WILNALISTNLIHSIRS-TGLNISQH-DNDDNYCYFM-LENEKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLILSLSLE----------VNIL- ----------------MVN------------------TRDFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----A-ECWHAHMEK------------------L-----RKCLSH--------------- L-------------------------------------YVQ------------------- ------------------------------------------------------------ ------------- >213.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIL----------KILK---EI---------TFLI------------- ---MTVLGIL------------GNMSVSVNYMFSWWGS---P-----EKKSVHL-ILIHL -------IFTNIIILLVKGLPKTI------------AAFGLRNFLDDIGCKIIVYMERL- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSA------WHILLFF LFF---------WILNALISVNLIHSTTN-TRLNVSQL-KSDDNYCYFM-LPIQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYVAFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLFLTLSSE----------VNIL- ----------------MVN------------------TRDFLTL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-ECRHVQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >213.1-m ---------------------------------------------MLALRN----YIQIN TP-------------------WC----MC-LFVTPLTPCLPEYWDPDSLRVE--GPTESS LRHNTASCTLKNTIMQNVQFRSMSS---ITDAFFKM----------------YLHTRK-- ----------EEMIL----------KILK---EI---------TFLI------------- ---MTVLGIL------------GNMSVSVNYMFSWWGS---P-----EKKPIHL-ILIHL -------IFTNIIILLVKGLPKTI------------AAFGLRNFLDDIGCKIIVYMERL- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRLKSA------WHILLFF LFF---------WILNALISVNLIHSTTN-TRLNVSQL-KSDDNYCYFM-LPIQKIKWIV LPLMVVRDAVFQ-----------GAMG-GASGYVAFLLHKHHQH----VLYFQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLFLTLSSE----------VNIL- ----------------MVN------------------TRDFLTL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-ECRHVQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >213.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MIL----------KILK---EI---------TFLI------------- ---MTVLGIL------------GNMSVSVNYMFSWWGS---P-----EKKPIHL-ILIHL -------IFTNIIILLVKGLPKTI------------AAFGLRNFLDDIGCKIIVYMERL- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRLKSA------WHILLFF LFF---------WILNALISVNLIHSTTN-TRLNVSQL-KSDDNYCYFM-LPIQKIKWIV LPLMVVRDAVFQ-----------GAMG-GASGYVAFLLHKHHQH----VLYFQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLFLTLSSE----------VNIL- ----------------MVN------------------TRDFLTL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-ECRHVQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >213-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------MFSWWGS---P-----EKKPIHL-ILIHL -------IFTNIIILLVKGLPKTI------------AAFGLRNFLDDIGCKIIVYMERL- ---TRGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRTKSS------WHILLFF LFF---------WILNALISVNLIHSTTN-TRLNVSQL-KSDDNYCYFM-LPIQKIKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLFLTLSSE----------VNIL- ----------------MVN------------------TRDFLTL---------------- ---G--YA-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----V-ECRHVQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >208-s -----------------MFAS--------------------------------------- -----------------------------WTHV--------------------------- -----------------------------------------------------FLPRK-- ----------KEMVL----------KYIN---KVN-------KISLF------------- ---MTVVGTL------------GNMFVSVNYTFSYSGS---S-----EKKPIYL-ILIHL -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSFLTVI-------QAVIISPRAS-GWS-RLRPESA------WHILPFF SSF---------WILNALISINLIYSIRS-TSLNISQQ-INYENSCYFT-VENQEIKWIF LILMVLRDALFQ-----------VAMG-GASGYMIFLLHKHHHH----VLYLQNSKFL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIINISSK----------DNTL- ----------------MIN------------------TREFLTL---------------- ---C--YP-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----S-KIWHAYWEK------------------L-----SKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >208-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIN---KVN-------KISLF------------- ---MTVVGTL------------GNMFVSVNYTFSYWGS---S-----EKKPIYL-ILIHL -------AFTNILILLTKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSFLTVV-------QAVIISPRAS-GWN-RLRPESA------WHILPFF SSF---------WILNALISINLIHSIRS-TSLNISQQ-INYENSCYFT-VENQEIKWIF LILMVLRDALFQ-----------VAMG-GASGYMVFLLHKHHHH----VLYLQNSKFL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIINISSK----------DNTL- ----------------MIN------------------TREFLTL---------------- ---C--YP-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----S-KFWHAHWEK------------------L-----SKCL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >208-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KYIN---KVN-------KISLF------------- ---MTVVGTL------------GNMFVSVNYTFSYWGS---S-----EKKPIYL-TLIHL -------AFTNILILLAKGLPKTI------------LAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSFLTVI-------QAVIISPRAS-GWS-RLRPESA------WHILPFF SSF---------WILNALISINLIHSIRS-TSLNISQQ-INYENSCYFT-VENQEIKWIF LILMVLRDALFQ-----------GAMG-GASGYMVFLLHKHHHH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWTDCAFSLIINISSK----------DNTL- ----------------MIN------------------TREFLTL---------------- ---C--YP-----------------------T-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----S-KFWHAHWEK------------------L-----SKCF----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >222-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---ET---------IFFF------------- ---MTMIGTL------------GNISVSVDYFFCLLEG---V-----KKKPIHL-ILIHL -------AFTNILILLTKGFRKTV------------AAFGLRNFLDDIGCKSIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSA------WHILPFF SFF---------WILNGLISVNLIHSTTN-TRLNISHF-RGDESNCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >222-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---ET---------FFFF------------- ---MTTIGTL------------GNMSVSVDYFFRLLEG---V-----KKKPIQL-ILIHL -------AFTNILILLTKGFRKTV------------AAFGLRNFLDDIGCKSIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSA------WHILPFL SFF---------WVLNGLISVNLIHSTTN-TRLNVSHF-RGDENNCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLYKHHQH----VFYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSFFLSLSLE----------EYSL- ----------------MVN------------------IHEFLTL---------------- ---G--YA-----------------------I-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----T-EQWET----------------------L-----KQCGSH--------------- LSDQ-------------------------------------------------------- ------------------------------------------------------------ ------------- >222-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---ET---------FFFF------------- ---MTMIGTL------------GNISVSVDYFFRLLEG---V-----KKKPIHL-ILIHL -------AFTNILILLTKGFRKTV------------AAFGLRNFLDDIGCKSIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRPKYA------WHILPFL SFF---------WVLNGLISVNLIHSTTN-TRLNISHF-RGDESNCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLYKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCVFSFFLSLSLE----------EYSL- ----------------MVN------------------IHEFLTL---------------- ---G--YA-----------------------I-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----T-EQWET----------------------L-----KQCVSH--------------- LSDQ-------------------------------------------------------- ------------------------------------------------------------ ------------- >188/222.1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---EI---------FFFF------------- ---MTMIGTL------------GNISVSVDYFFRLLEG---V-----KKKPIHL-ILIHL -------AFTNILILLTKGFRKTV------------AAFGLRNFLDDIGCKIIVYLERM- ---ARGLSICTSSFLTVV-------QAIIISPRAS-GWR-RLRPKSA------WHILPFF SFF---------WILNALISVNLIHSTTN-TKLNVSQL-RGDDSNCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMMCFVF---FYWTDCAFSFFLSLSLE----------EYSL- ----------------MVN------------------IHEFLTL---------------- ---G--YA-----------------------I-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----A-EQWET----------------------L-----KQCVSH--------------- LSDQ-------------------------------------------------------- ------------------------------------------------------------ ------------- >188-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---ET---------FFFF------------- ---MTMIGTL------------GNISVSVDYFFHLLEG---V-----KKKPIHL-ILIHL -------AFTNILILLTKGFRKTV------------AAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPTGS-GWR-RLRPKSA------WHILPFF SFF---------WILNALISMNLTHSIRS-TGLNISQL-RNGDNYCYIM-LESQEIKWIF LILMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQQ----VLYLQNSKFL-- ---YKTPPELRAAQSVLLLMLCFVF---FYWTDCAFSFFLSLSLE----------EYSL- ----------------MVN------------------IHEFLTL---------------- ---G--YA-----------------------I-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----A-EQWET----------------------L-----KQCVSH--------------- LSDQ-------------------------------------------------------- ------------------------------------------------------------ ------------- >188-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---EI---------FFFF------------- ---MTMIGTL------------GNISVSVDYFFRLLEG---V-----KKKPIHL-ILIHL -------AFTNIIILLTKGFRKTV------------AAFGLRNFLDDIGCKFIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPTGS-WWR-RLRPKSA------WHILSFF SFF---------WILNALISMNLTHSIRS-TGLNISQL-RNGDNYCYIM-LESQEIKWIL LIIMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMMCFVF---FYWTDCAFSFFLSLSLE----------EYSL- ----------------MVN------------------IHEFLTL---------------- ---G--YA-----------------------I-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----A-EQWET----------------------L-----KQCVSH--------------- LSDQ-------------------------------------------------------- ------------------------------------------------------------ ------------- >188-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---EI---------FFFF------------- ---MTMIGTL------------GNISVSVDYFFRLLEG---V-----KKKPIHL-ILIHL -------AFTNIIILLTKGFRKTV------------AAFGLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSLLTVV-------QAIIISPTGS-WWR-RLRPKSA------WHILSFF SFF---------WILNALISTNLTHSIRS-TGLNISQL-RNGDNYCYIM-LESQEIKWIL LIIMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMMCFVF---FYWTDCAFSFFLSLSLE----------EYSL- ----------------MVN------------------IHEFLTL---------------- ---G--YA-----------------------I-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----A-EQWET----------------------L-----KQCVSH--------------- LSDQ-------------------------------------------------------- ------------------------------------------------------------ ------------- >188.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGL----------QFIK---ET---------IFLF------------- ---MTIIGTL------------GNISVSVDYFFRLLEG---V-----KKKPIHL-ILIHL -------AFINILVLLPKGFRKTI------------ASFGLRNFLDDIGCKIIVYLERM- ---TRGLSICTSSLLTVI-------QAIIISPRAS-GWR-RLKPKSA------WHILPFF SFF---------WILNALISTNLIHSIRS-IGLNISQL-KNGANYCYIM-LENQEIKWIV LIIMVLRDVVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLFLSFSSE----------EYSL- ----------------MLN------------------IHEFLTI---------------- ---G--YA-----------------------I-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----A-EQWET----------------------L-----KQCFSH--------------- LSAQLT----------------------------RKNSLLQR------------------ ----------------CG------------------------------------------ ------------- >188.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------QFIK---ET---------IFLF------------- ---MTMIGTL------------GNISVSVDYFFLLLEG---V-----KKKPIHL-ILIHL -------TFTNILILLTKGFRKTI------------AAFGLRNFLDDIGCKIIVYLERV- ---GRGLSICTSSLLTVV-------QAIIISPRAS-GWN-RLKPKSA------WHILPFF SFF---------WILNALISTNLIHSIRS-TGLNISQL-RNGDNYCYIM-LESQEIKWIL LIIMVLRDAAFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLFLSFSSE----------EYSL- ----------------MLN------------------IHEFLTI---------------- ---G--YA-----------------------I-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----A-EQWET----------------------L-----KQCFSH--------------- LSAQLT----------------------------RKNSLLQR------------------ ----------------CG------------------------------------------ ------------- >188/222-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KFIK---KM---------LFPS------------- ---MTVVGIL------------GNMSVSVNYMFSWWGS---P-----EKKLIHL-ILIHL -------TFTNIILLLAKRLPKTK------------AAFGLRNFLGDIGCKIIIYLERV- ---ARGLSICTSSLLTVV-------QAIIISPRRS-GWQ-RLRPKSA------WHLLPFF SFF---------WVFNALISVNLIHSTTS-TRLNVSQL-RGDEGYCYFI-LPSQKIKWIF FPLMVLRDVVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDSAFSLIINMSLM----------ENSL- ----------------IIN------------------IQEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGL------L ----T-GFWHVQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >212.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KFIK---KM---------LFPS------------- ---MTVVGIL------------GNMSVSVNYMFSWWGS---P-----EKKLIHV-ILIHL -------AFTNIILLLAKRLPKTK------------AAFGLRNFLDDIGCKTIVYLERM- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-KLRPKSA------WHILPFL SFF---------WLLNASISVNLIHSTTN-TRLNVSQL-RSDESDCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLYKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIINMSLM----------EIP-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >212.3-s --------------------------M-----------------LPLSYKH----HG--- ------------------------------VAL--------------------------- -EHYTG-----------------------------------------------CHPED-- ----------VKMVL----------KFIK---KM---------LFPS------------- ---MTVVGIL------------GNMSVSVNYMFSWWGS---P-----EKKLIHV-ILIHL -------AFTNIILLLAKRLPKTK------------AAFGLRNFLDDIGCKTIVYLERM- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-KLRPKSA------WHILPFL SFF---------WLLNASISVNLIHSTTN-TRLNVSQL-RSDESDCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLYKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIINMSLM----------ENSL- ----------------IIN------------------IQEFVTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGV------L ----T-GFWHVHLGK------------------L-----RKC------------------ RS--------------------------------------FI------------------ ----------------CSI------------------------------------SVGRR LSVLQYYG----- >212.4-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KFIK---KM---------LFPS------------- ---MTVVGIL------------GNMSVSVNYMFSWWGS---P-----EKKLIHV-ILIHL -------AFTNIILLLAKRLPKTK------------AAFGLRNFLDDIGCKTIVYLERM- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-KLRPKSA------WHILPFL SFF---------WLLNASISVNLIHSTTN-TRLNVSQL-RSDESDCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLYKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLII-------------------- ------------------------------------------------------------ -------------------------------------------------------IC--- --------L--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >212-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KFIK---KM---------LFPS------------- ---MTVVGIL------------GNMSVSVNYMFSWWGS---P-----EKKLIHV-ILIHL -------AFTNIILLLAKRLPKTK------------AAFGLRNFLDDIGCKTIVYLERM- ---ARGLSICTSSLLTVV-------QAITISPRAS-GWR-KLRPKSV------WHILPFL SFF---------WVLNASISVNLIHSTTN-TKLNVSQL-RSDESDCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLYKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWIDCAFSLIINISLM----------ENSL- ----------------IIN------------------IQEFVTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGV------L ----T-GFWHVHLGKQKMSLIY----------LF-----NKCWEKTLSSSVLW------V RSDP-T----------------------------KKVKNLFI------------------ ----------------LTF------------------------------------PGDSS LELRINYKLTL-- >188/222.2-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KFIK---KM---------LFPS------------- ---MTVVGIL------------GNMSVSVNYMFSWWGS---P-----EKKLIHI-ILIHL -------AFTNIILLLAKRLPKTK------------AAFGLRNFLDDIGCKIIVYLERM- ---ARGLSICTSSFLTVV-------QAIIISPRAS-GWR-RLRPKSA------WHILPFF SFF---------WILNALISVNLIHSTTN-TKLNVSQL-RGDDSNCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMMCFVF---FYWTDCAFSFFLSLSLE----------EYSL- ----------------MVN------------------IHEFLTL---------------- ---G--YA-----------------------I-F--S---P--------------FV--- --------L-------------------------------IHR-------DGL------L ----A-EQWET----------------------L-----KQCVSH--------------- LSDQ-------------------------------------------------------- ------------------------------------------------------------ ------------- >188/212/222.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------KFIK---KM---------LFPS------------- ---MTVVGIL------------GNMSVSVNYMFSWWGS---P-----EKKLIHI-ILIHL -------AFTNIILLLAKRLPKTK------------AAFGLRNFLDAIGCKIIVYLERM- ---ARGLSICTSSLLTVV-------QAVIISPRAS-GWR-KLRPKSA------WHILPFF SFF---------WILNGLISVNLIHSTTN-TRLNISHF-RGDESNCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPE--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >219.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MTMVGIL------------GNMSVSVHYMFSWWGS---P-----EKKPIHL-ILTHL -------TFTNIILLLAKGLQKTI------------TVFRLRNFLDDIGCKIIVYLERV- ---ARGLSICTSSFLTVV-------QAIIISPRAS-GWS-RLRPKSA------WHVLPFF SFF---------WVLNASISVNLIHSIRS-IGMNTSQH-KNSDNYCYMT-LESQEMKWIV LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWADCAFSLFLSLSLG----------DYLL- ----------------M-------------------------KL---------------- ---S--GS-----------------------L-A--H---P--------------LT--- --------CSDQPPKFGGSQTKMATAAAVAQGDSPAGRAAVLR-------SGL------W ----P-GVPCPQ-RV------------------LP---QRPCASA--------------- --SSRRCQ-----------------------VLWRTLSPVQTNFPSSAGPGQRWRPLLLW PRATPQPGGQPSSGPDCGQV------------SPAHKGRCLSGPVPPPLPEAVRLSGAPS HLFRPIY------ >188/212/222-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------MNLIHSIIS-TGMNISQH-KNSDNYCYFM-QESQEIKWIV LPLMVLRDALFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIINISLM----------ENSL- ----------------IIN------------------IQEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGV------L ----T-GFWHVHLGK------------------L-----RKCCSF--------------- TCSISV---------------------------GRRLSVLQY------------------ ----------------YG------------------------------------------ ------------- >188/212/222.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTW-----------------QVSPSQS-CPRVCLQ------------- --------------------HRGPEGV--------------------KKKPIHL-ILIHL -------AFTNILILLTKGFRKTV------------AAFGLRNFLDDIGCKIIVYLERM- ---ARGLSICTSSLLTVV-------QAVIISPRAS-GWR-KLRPKSA------WHILPFF SFF---------WILNGLISVNLIHSTTN-TRLNISHF-RGDESNCYFM-LPSQKIKWIF LPLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCAFSLIINISLM----------ENSL- ----------------IIN------------------IQEFLTL---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------L-------------------------------IHR-------DGV------L ----T-GFWHVHLGK------------------L-----RKCRSF--------------- TCSISV---------------------------GRRLSVLQY------------------ ----------------YG------------------------------------------ ------------- >212.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------M----------------------------LFPS------------- ---MTVVGIL------------GNMSVSVNYMFSWWGS---P-----EKKLIHV-ILIHL -------AFTNIILLLAKRLPKTK------------AAFGLRNFLDDIGCKTIVYLERM- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-KLRPKSA------WHILPFL SFF---------WLLNASISVNLIHSTTN-TRLNVSQL-RSDESDCYFM-LPSQKIKWIF LPLMVLRMQCFR-----------VPWE-GPVATWYFFSTN-----------TINMSST-- ---FRTP---------------------------SFSTELPLS----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >196-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKL----------KIVLNISEIT--------VFLL------------- ---LTGLGTV------------ANISIFVNYICTFMGS---------GKKSIHL-ILIHL -------ALTNITLLFSKVMPVTI------------AALGLRHFLGDVGCHVIVYLERM- ---ARGLSICTSSLLTVV-------QAVIMSPRVS-WWG-RLRLRSK------WHVLLSL FFL---------WILNMLTSMNLLLSIRD-TATDTLQL-RQISEYCYFK-KESQKRNNIF LILMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCVVSLYLSSSLN----------NDSL- ----------------TMH------------------FQEFLTI---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IHR-------DGL------L ----A-ECCHAH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >196-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKL----------KIVLNISEIT--------VFLL------------- ---FTGLGTV------------ANVSIFVNYICTFMGS---------GKKSIYL-ILIHL -------ALTNITLLFSKVMPVTI------------AALGLRHFLGDIGCHVIVYLERM- ---ARGLSICTSSLLTVV-------QAVIMSPRAS-WWG-RLRLRSK------WHVLLSL FFL---------WILNTLISMNLLLSIRD-TATDTLQL-RQISEYCYFK-KESQKRNNIF LILMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRAPPEMRAAQSVLLLMLCFVF---FYWTDCVVSLYLSSSLN----------NDSL- ----------------TIH------------------FQEFLTV---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IQR-------DGL------L ----A-ECCHAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >196-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKL----------KIVLNISEIT--------VFLL------------- ---FTGLGTV------------ANVSIFVNYICTFMGS---------GKKSIYL-ILIHL -------ALTNITLLFSKVMPVTI------------AALGLRHFLGDIGCHVIVYLERM- ---ARGLSICTSSLLTVV-------QAVIMSPRAS-WWG-RLRLRSK------WHVLLSL FFL---------WILNTLISMNLLLSIRD-TATDTLQL-RQISEYCYFK-KESQKRNNIF LILMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTP----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >196.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCVVSLYLSSSSN----------NDSL- ----------------TIH------------------FQEFLTI---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IQR-------DGL------L ----A-ECCHAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >196.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKL----------KIVLNISEIT--------VFLL------------- ---FTGLGTV------------ANVSIFVNYICTFMGS---------GKKSIYL-ILIHL -------ALTNITLLFSKVMPVTI------------AALGLRHFLGDIGCHVIVYLERM- ---ARGLSICTSSLLTVV-------QAVIMSPRAS-WWG-RLRLRSK------WHVLLSL FFL---------WILNMLISMNFLLSIRD-TATDTLQL-RQISEYCYFK-KESQRRNNIF LILMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCVVSLYLSSSSN----------NDSL- ----------------TIH------------------FQEFLTI---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IQR-------DGL------L ----A-ECCHAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >196.3-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLS--------------------------------------------- ------------------------------------------------------------ ------------------------------------AAPRLKH------CA-----ERM- ---ARGLSICTSSLLTVV-------QAVIMSPRAS-WWG-RLRLRSK------WHVLLSL FFL---------WILNMLISMNFLLSIRD-TATDTLQL-RQISEYCYFK-KESQRRNNIF LILMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFVF---FYWTDCVVSLYLSSSSN----------NDSL- ----------------TIH------------------FQEFLTI---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IQR-------DGL------L ----A-ECCHAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >196-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------MPVTI------------AALGLRHFLGDIGCHVIVYLERM- ---ARGLSICTSSLLTVV-------QAVIMSPRAS-WWG-RLRLRSK------WHVLLSL FFL---------WILNTLISMNLLLSIRD-TATDTLQL-RQISEYCYFK-KESQKRNNIF LILMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPEMRAAQSVLLLMMCFVF---FYWTDCVVSLYLSSSSN----------NDSL- ----------------TIH------------------FQEFLTV---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IQR-------DGI------L ----A-ECCHAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >196-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKL----------KIVLSISEIT--------IFLL------------- ---LIGLGTV------------VNVFIFVNYICTFMGS---------GKKSIHL-ILIHL -------ALTNITLLFSKAMPVTI------------AAFGLRHFLGDVGCHIFVYLERM- ---ARGLSICTSSLLTVV-------QAVIMSPRVS-WWG-RLRLRSK------WHVLLSV FFF---------WILNMLISMNLLFSIRD-IATDTLQL-SKNSEYCYFK-KESQKRNNIF LILMVLRDAAFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFIF---IYWTDCVVSLYLSSSWN----------NDSL- ----------------TVH------------------FQEFLTV---------------- ---G--YA-----------------------V-F--S---P--------------FI--- --------L-------------------------------IHR-------DGL------L ----A-ECCHAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >197-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------DPVKGT------------VFLC------------- ---LTGLGTV------------GNSLVFVSYMHMFQST---------EQKPIHL-ILAHL -------TLTNIIMLLSKGMPKTI------------EAFNFGNYLNDTSCKAVVYLARV- ---SRGLSICTSSLLTVV-------QAITISPRHS-MWQ-RLNLKTP------QHILFSL LCL---------WILNSLISMNLLSYIKNVSSLNITQF-KKKGNYCYFL-PESWITRWIF LTLM-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >197.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------DPVKGT------------VFLC------------- ---LTGLGTV------------GNSLVFVSYMHMFQST---------EQKPIHL-ILAHL -------TLTNIIMLLSKGMPKTI------------EAFNFGNYLNDTSCKAVVYLARV- ---SRGLSICTSSLLTVV-------QAITMSPRHS-MWQ-RLNLKTP------QHTLFSL LCL---------WILNSLISMNLPYYIKNVSSLNITQF-KKNGNYCYFL-PESWITRWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWADCFISLFFTFSIE----------NHST- ----------------VLY------------------VPEFLTL---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IHR-------DEH------V ----I-KCFHTQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >197-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------DPVKGT------------VFLC------------- ---LTGLGTV------------GNSLVFVSYMHMFQST---------EQKPIHL-ILAHL -------TLTNIIMLLSKGMPKTI------------EAFNFGNYLNDTSCKAVVYLARV- ---SRGLSICTSSLLTVV-------QAITMSPRHS-MWQ-RLNLKTP------QHTLFSL LCL---------WILNSLISMNLPYYIKNVSSLNITQF-KKNGNYCYFL-PESWITRWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWADCFISLFFTFSIE----------NHST- ----------------VLY------------------VPEFLTL---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IHR-------DEH------V ----I-KCFHTQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >197-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------DPVKGT------------VFLC------------- ---LTGLGTV------------GNSLVFVSYMHMFQST---------EQKPIHL-ILAHL -------TLTNIIMLLSKGMPKTI------------EAFNFGNYLNDTSCKAVVYLARV- ---SRGLSICTSSLLTVV-------QAITMSPRHS-MWQ-RLNLKTP------QHTLFSL LCL---------WILNSLISMNLPYYIKNVSSLNITQF-KKNGNYCYFL-PESWITRWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWADCFISLFFTFSIE----------NHST- ----------------VLY------------------VPEFLTL---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IHR-------DEH------V ----I-KCFHTQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >197-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------DPVKGT------------VFLC------------- ---LTGLGTV------------GNSLVFVSYMHMFQST---------EQKPIHL-ILAHL -------TLTNIIMLLSKGMPKTI------------EAFNFGNYLNDTSCKAVVYLARV- ---SRGLSICTSSLLTVV-------QAITMSPRHS-MWQ-RLNLKTP------QHTLFSL LCL---------WILNSLISMNLPYYIKNVSSLNITQF-KKNGNYCYFL-PESWITRWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWADCFISLFFTFSIE----------NHST- ----------------VLY------------------VPEFLTL---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IHR-------DEH------V ----I-KCFHTQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >197.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------DPVKGT------------VFLC------------- ---LTGLGTV------------GNSLVFVSYMHMFQST---------EQKPIHL-ILAHL -------TLTNIIMLLSKGMPKTI------------EAFNFGNYLNDTSCKAVVYLARV- ---SRGLSICTSSLLTVV-------QAITMSPRHS-MWQ-RLNLKTP------QHTLFSL LCL---------WILNSLISMNLPYYIKNVSSLNITQF-KKNGNYCYFL-PESWITRWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPLN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >197.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------MSPRHS-MWQ-RLNLKTP------QHTLFSL LCL---------WILNSLISMNLPYYIKNVSSLNITQF-KKNGNYCYFL-PESWITRWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVLLLMLCFLF---FYWADCFISLFFTFSIE----------NHST- ----------------VLY------------------VPEFLTL---------------- ---G--YA-----------------------V-L--S---P--------------FM--- --------L-------------------------------IHR-------DNM------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >211-s --------------------------M-----------------LQTSLEA--------- -PR--------------------------------------------------------- ---------------------------------------------------PLAFPRSSI ---P---TSDLRMVL----------DPVKGT------------VFLC------------- ---LTGLGTV------------GNSLVFVSYMHMFQST---------EQKPIHL-ILAHL -------AFTNIIMLFSKGIRRTI------------GAFNFDNFLNDTSCKVVVYLTRV- ---SRGLSICTSSLLTVV-------QAITISPRHS-MCQ-RLKLKTP------QHILSSL LCL---------WILNSLISMNLLSYVKNVNCVNITQF-REDGDFCYFL-PESWITRWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQNSKLL-- ---YRTPPELRAAQSVILLMMCFIF---FYWADCFISLFFTLTIE----------NYST- ----------------VLD------------------VPEFLTI---------------- ---G--YA-----------------------V-L--S---P--------------FI--- --------L-------------------------------IHR-------DGH------L ----I-KCCHTQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >211-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVL----------DPVKGT------------VFLC------------- ---LTGLGTV------------GNSLVFVSYMHMFQST---------EQKPIHL-ILAHL -------AFTNIIMLFSKGIRRTI------------GAFNFDNFLDDTSCKVAVYLARV- ---SRGLSICTSSLLTVV-------QAITISPRHS-MCQ-RLKLKTP------QHILSSL LCL---------WILNSLISMNLLSYVKNVNRVNITQF-REDGDFCYFL-PESWITRWIF LTLMVLRDAVFQ-----------GAMG-GASGYMVFLLHKHHQH----VLYLQTSKLL-- ---YRTPPELRAAQSVLLLMMCFIF---FYWADCFISLFFTLTIE----------NYST- ----------------VLD------------------VPEFLTI---------------- ---G--YA-----------------------V-L--S---P--------------FI--- --------L-------------------------------IHR-------DEH------L ----I-KCCHTQ------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >213.1-p -----------------MYSSDPYLAL-----------------LMLSLK---------- ----------------------C----IC------------------------------- ----------------------------------------------------ILYTRK-- ----------EEMTL----------KILK---EI---------TFLV------------- ---MTVLGIL------------GNMSVSVNYMFSWWGS---H-----EKKPIHL-ILIHL -------IFTNIIILLVKGLPKTI------------AAFGLRNFLDDIGCKIIVYMERL- ---ARGLSICTSSLLTVV-------QAIIISPRAS-GWR-RLRPKSA------WPILLFF LFF---------L-----------------------------DTQCFDK-CEPNP----- ------------------------------------LYHK-------------------- -----------------------------YKIECITT----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >213.1-s ---------------------------------------------MHALRN----YIQIN TP-------------------LC----MC-LFVTPLTPCLPEYWDPDSMRVE--GPTESS PRHNTASCTLKNTIMQNVQFRSMSS---ITDAFFKM----------------YLHTRK-- ----------EEMIL----------KILK---EI---------TFLI------------- ---MTVLGIL------------GNMSVSVNYMFSWWGS---P-----EKKSVHL-ILIHL -------IFTNIIILLVKGLPKTI------------AAFGLRNFLDDIGCKIIVYMERL- ---ARGLSICTSSLLTVV-------QAIIISPR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >199.2-x ------------------------------------------------MQN--------- ------------------------------------------------------------ -----------------VLFRSMSS---ITDAFFKMY--------------FILHTRK-- ----------EEMIL----------KLIK---KI---------LFLF------------- ---MTVLGIM------------GNMSVSVNYMFSWWEG---A-----EKKPVHL-ILIHL -------AFTNTVILLAKGLPKTI------------VAFGLRNFLDDLGCKIIVYLERV- ---AHGLSLRQQ------------------SPHCG-PGH-HHQPQSI------------- ------------WMEDAQAKVCMAH-------------------------------PSIL LILLVI------QCINKYEPNKF-----------------HHKY---------------- ---------------------------K-------------------------------- --------------------------------------TEYITI---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal32-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MIFS- FFYF--------WSFNLSFSSNRIFYVGAYTNMSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTSRDVFLV-----------GVML-TTSAYMVIILFRHQRQ----CKHLHSNSH--- ---LRASPEKRATQIILLLVFFFVV---MYWVDFIISSSSVLLWR----------YDPV- ----------------ILT------------------VQKFVMC---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DNR------I ----I-IMLENMQ--------------------------SK------------------- -------------------HCQN---------FFKCFFFFFLK---------------TY ------------------------------------------------------------ ------------- >39.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-IFCQL -------TFIHIIMVITGWDIFTT------------EMFDLLNIENDIICKATSYLNRA- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMISS- FFYI--------WSFNLLFIINRIFYTGAYTNVSDTNQ-LKVTKYCSLF-PMNNIIKGLA STIVTLRDVFLV-----------GVML-STSTYMVIILFRHQRQ----CKHLHSKSQ--- ---LRASPEKRATQTILLLVVFFVV---LYWVDFIMSFRTIHLWM----------YDPV- ----------------MLT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----I-TMLKNMQ--------------------------KV------------------- -------------------CHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >39.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-ISCQL -------TFIHIIMVITGWDIFTA------------DMFDLLNIENDIICKATSYLNRA- ---MRGLSISITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLLFIINRIFYTGAYTNVSDTNQ-VKVTKYCSLF-PMNNIINGLA LTVVTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSKCQ--- ---LRASPEKRATQTILLLVVFFVV---LYWVDFIMSFRTFHLWM----------YDPV- ----------------MLT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------IIS-------DNR------I ----I-TMLKNMQ--------------------------KV------------------- -------------------CHQI---------CKKVYFFSYF------------------ ------------------------------------------------------------ ------------- >39.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-ISCQL -------TFIHIIMVITGWDIFTA------------DMFDLLNIENDIICKATSYLNRA- ---MRGLSISITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLLFIINRIFYTGAYTNVSDTNQ-VKVTKYCSLF-PMNNIINGLA LTVVTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---LYWVDFIMSFRTFHLWM----------YDPV- ----------------MLT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------IIS-------DNR------I ----I-TMLKNMQ--------------------------KV------------------- -------------------CHQI---------CKKVYFFSYF------------------ ------------------------------------------------------------ ------------- >39.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVFYV------------- ---QAVLGTL------------ANIFLLFFYTIIILC----H-----RSKPMDL-ISCQL -------TFIHIIMVITGWDIFTA------------DMFDLLNIENDIICKATSYLNRA- ---MRGLSISITCLLSVF-------QAVMISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLLFIINRIFYTGAYTNVSDTNQ-VKVTKYCSLF-PMNNIINGLA STIVTLRDVFLV-----------GVML-STSTYMVIILFRHQRQ----CKHLHSKSQ--- ---LRASPEKRATQTILLLVVFFVV---LYWVDFIMSFRTFHLWM----------YDPV- ----------------MLT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------IIS-------DNR------I ----I-TMLKNMQ--------------------------KV------------------- -------------------CHQI---------CKKV------------------------ ------------------------------------------------------------ ------------- >39.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-ISCQL -------TFIHIIMVITGWDIFTA------------DMFDLLNIENDIICKATSYLNRA- ---MRGLSISITCLLSVF-------QAVMISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLLFIINRIFYTGAYTNVSDTNQ-VKVTKYCSLF-PMNNIINGLA STIVTLRDVFLV-----------GVML-STSTYMVIILFRHQRQ----CKHLHSKSQ--- ---LRASPEKRATQTILLLVVFFVV---LYWVDFIMSFRTFHLWM----------YDPV- ----------------MLT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------IIS-------DNR------I ----I-TMLKNMQ--------------------------KV------------------- -------------------CHQI---------CKKV------------------------ ------------------------------------------------------------ ------------- >39.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-ISCQL -------TFIHIIMVITGWDIFTA------------DMFDLLNIENDIICKATSYLNRV- ---MRGLSISITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLLFIINRIFYTGAYTNVSDTNQ-VKVTKYCSLF-PMNNIINGLA STIVTLRDVLLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSKSQ--- ---LRASPEKRATQTILLLVVFFVV---LYWVDFIMSFRTFHLWM----------YDPV- ----------------MLT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------IIS-------DNR------I ----I-TMLKNMQ--------------------------KV------------------- -------------------CHQI---------CKKV------------------------ ------------------------------------------------------------ ------------- >39.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVFYV------------- ---QAVLGTL------------ANIFLLFFYTIIILC----H-----RSKPMDL-ISCQL -------TFIHIIMVITGWDIFTT------------EMFDLLNIENGIICKATSYLNRV- ---MRGLSICITYLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLLFIINRIFYTGAYTNVSDTNQ-VKVTKYCSLF-PMNNIINGLA STIVTLRDVLLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSKSQ--- ---LRASPEKRATQTILLLVVFFVV---LYWVDFIMSFRTFHLWM----------YDPV- ----------------MLT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------IIS-------DNR------I ----I-TMLKNMQ--------------------------KV------------------- -------------------CHQI---------CKKV------------------------ ------------------------------------------------------------ ------------- >33.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVFYV------------- ---QAVLGTL------------ANIFLLFFYTIIILC----H-----RSKPMDL-ISCQL -------TFVHIIMVITGWDIFTT------------DMFDLLNIENDFICKATSYLNRV- ---MRGISICITCLLSVF-------QAVTISPNTS-VLA-KFKYKLK------KYMISS- FFYF--------WSFNLSFSINRIFYTGAYTNVSETNQ-LKVTKYCSIF-PMDYIIKGLI STMTALRDVFLV-----------GVML-TTSAYMIIILFRHQRQ----CMHLHSDSH--- ---LRASPEKRATHIILLLVFFYVV---MYWIDFIMSSRTVLLWM----------YDPV- ----------------LLT------------------VQKFVIN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----N-IMIKNMQ--------------------------KV------------------- -------------------CHQI---------FFKF-NFSFL------------------ ------------------------------------------------------------ ------------- >33.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVFYV------------- ---QAGLGTL------------ANIFLLFFYTIIILC----H-----RSKPMDL-ISCQL -------TFVHIIMVITGWDIFTT------------DMFDLLNIENDFICKATSYLNRV- ---MRGISICITCLLSVF-------QAVTISPNTS-VLA-KFKYKLK------KYMISS- FFYF--------WSFNLSFSINRIFYTGAYTNVSETNQ-LKVTKYCSIF-PMDYIIKGLI STMTALRDVFLV-----------GVML-TTSAYMIIILFRHQRQ----CMHLHSDSH--- ---LRASPEKRATHIILLLVFFYVV---MYWIDFIMSSRTVLLWM----------YDPV- ----------------LLT------------------VQKFVIN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----N-IMIKNMQ--------------------------KV------------------- -------------------CHQI---------FFKF-NFSFL------------------ ------------------------------------------------------------ ------------- >33.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------LLS-------NVSYV------------- ---QAGLGTL------------ANIFLLFFYTIIILC----H-----RSKPMDL-ISCQL -------TFVHIIMVITGWDIFTT------------DMFDLLNIENDFICKATSYLNRV- ---MRGISICITCLLSVF-------QAVTISPNTS-VLA-KFKYKLK------KYMISS- FFYF--------WSFNLSFSINRIFYTGAYTNVSETNQ-LKVTKYCSIF-PMDYIIKGLI STMTALRDVFLV-----------GVML-TTSAYMIIILFRHQRQ----CMHLHSDSH--- ---LRASPEKRATHIILLLVFFYVV---MYWIDFIMSSRTVLLWM----------YDPV- ----------------LLT------------------VQKFVIN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----N-IMIKNMQ--------------------------KV------------------- -------------------CHQI---------FFKF-NFSFL------------------ ------------------------------------------------------------ ------------- >33-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVFYV------------- ---QAGLGTL------------ANIFLLFFYTIIILC----H-----RSKPMDL-ISCQL -------TFVHIIMVITGWDIFTT------------DMFDLLNIENDFICKATSYLNRV- ---MRGISICITCLLSVF-------QAVTISPNTS-LLA-KFKYKFK------KYMISS- FFYF--------WSFNLSFSINRIFYTGAYTNVSETNQ-LKVTKYCSLF-PMDYIIKGLI STMTALRDVFLV-----------GVML-TTSAYMIIILFRHQRQ----CMHLHSDSH--- ---LRASPEKRATHIILLLVFFYVV---MYWIDFIMSSRTVLLWM----------YDPV- ----------------LLT------------------VQKFVIN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----N-IMIKNMQ--------------------------KV------------------- -------------------CHQI---------FFKV------------------------ ------------------------------------------------------------ ------------- >33-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVFYV------------- ---QAGLGTL------------ANIFLLFFYTIIILC----H-----RSKPMDL-ISCQL -------TFVHIIMVITGWDIFTT------------DMFDLLNIENDFICKATSYLNRV- ---MSGISICITCLLSVF-------QAVMISPNTS-LLA-KFKYKLK------KYMIFS- FFYF--------WSFNLSFSINRIFYTGAYTNVSETNQ-LKVTKYCSIF-PMDYIIKGLI STMTALRDVFLV-----------GVML-TTSAYMIIILFRHQRQ----CMHLHSDSH--- ---LRASPEKRATHIILLLVFFYVV---MYWIDFITSSRTVLLWM----------YDPV- ----------------LLT------------------VQKFVIN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----N-IMIKNMQ--------------------------KV------------------- -------------------CHQI---------FFKF-NFSFI------------------ ------------------------------------------------------------ ------------- >33-x ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MN-- --------NFPIMF------------------SLN-------NVFYV------------- ---QAGLGTL------------ANIFLLFFYTIIILC----H-----RFKPMDL-ISCQL -------TFVHIIMVITGWDIFTT------------DMFDLLNIENDFICKATSYLNRV- ---MRGISICITCLLSVF-------QAVMISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIFYTGAYTNVSETNQ-LKVTKYCSIF-PMDYIIKGLI STMTALRDVFLV-----------GVML-TTSAYMIIILFRHQRQ----CMHLHSDSH--- ---LRASPEKRATHIILLLVFFYVV---MYWIDFIMSSRTVLLWM----------YDPV- ----------------LLT------------------VQKFVIN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----N-IMIKNMQ--------------------------KV------------------- -------------------CHQI---------FFKF-NFSFI------------------ ------------------------------------------------------------ ------------- >39-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVFYV------------- ---QAVLGTL------------ANIFLLFFYTIIILC----H-----RFKPMDL-ISCQL -------TFVHIIMVITGWDIFTT------------DMFDLLNIENDFICKATSYLNRV- ---MRGISICITCLLSVF-------QAVMISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIFYTGAYTNMSETNQ-VKVTKYCSLF-PMNNIINGLA STIVTLRDVLLV-----------GVML-TTSTYMVIILF--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >38-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-ISCQL -------TFIHIIMVITGWDIFTA------------DMFDLLNIENDIICKATSYLNRA- ---MRGLSISITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLLFIINRIFYTGAYTNVSDTNQ-VKVTKYCSLF-PMNNIIRGLI STIITLRDVFFV-----------GVML-STSTYMLIVLFRHQRQ----CKHLHSDSH--- ---LRASPEKRATQTILLLVFFYVV---MYWVDFIMSSRTVFLWM----------FDLV- ----------------MLT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----I-MILKSMQ--------------------------KI------------------- -------------------WHQI---------F--------------------------- ------------------------------------------------------------ ------------- >38-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NIFYF------------- ---QAGLGTL------------ANIFLLIFYTIIILC----H-----RSKPMDL-ISCQL -------TFIHIIMVITGWDIFTT------------EMFDLLNIENDIICKATSYLNRA- ---MRGLSISITCLLSVF-------QAVTISPNSA-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIFYTGAYINVSETNQ-VKVTKYCSLF-PMNNIIRGLI STIITLRDVFFV-----------GVML-STSTYMVIILFRHQRQ----CKHLHSDSH--- ---LRASPEKRATQTILLLVFFYVV---MYWVDFIMSSRTVFLWM----------YDPV- ----------------MLT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----L-MILKSMQ--------------------------KI------------------- -------------------WHQI---------F--------------------------- ------------------------------------------------------------ ------------- >38-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NIFYF------------- ---QAGLGTV------------ANIFLLIFYTIIILC----H-----RSKPMDL-ISCQL -------TFIHIIMVITGWDIFTA------------DMFDLLNIENDIICKATSYLNRA- ---MRGLSISITCLLSVF-------QAVTISPNSS-LLA-KLKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIFYTGAYTNMSETNQ-VKVTKYCSLF-PMNNIIRGLI STIITLRDVFFV-----------GVML-STSTYMLIVLFRHQRQ----CKHLHSKSH--- ---LRASPEKRATQTILLLVFFYVI---MYWVDFIMSSRTVFLWM----------FDPV- ----------------MLI------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----L-MILKSMQ--------------------------KI------------------- -------------------WHRF---------FKKC-NFSLM------------------ ------------------------------------------------------------ ------------- >38-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NIFYF------------- ---QAGLGTL------------ANIFLLIFYTIIILC----H-----RSKPMDL-ISCQL -------TFVHIIMVITGWDIFTT------------DMFDLLNIENDFICKATSYLNRV- ---MSGISICITCLLSVF-------QAVMISPNTS-LLA-KFKYKLK------KYMIFS- FFYF--------WSFNLSFSINRIFYTGAYTNMSETNQ-VKVTKYCSLF-PMNNIIRGLI STIITLRDVFFV-----------GVML-STSTYMLIVLFRHQRQ----CKHLHSKSH--- ---LRASPEKRATQTILLLVFFYVI---MYWVDFIMSSRTVFLWM----------FDPV- ----------------MLT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------I ----L-MILKSMQ--------------------------KI------------------- -------------------WHRF---------FKKC-NFSLM------------------ ------------------------------------------------------------ ------------- >38/39.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVFYV------------- ---QAGLGTL------------ANIFLLFFYTIIILC----H-----RPKPMDL-ISCQL -------TFIHIIMVITGWDIFTT------------DMFDLLNIENDIICKATAYLKRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLG-KFKHKLK------KYMIYS- FFYF--------WAFNLSFTINRIFYCGAYTNMSETNQ-LKVTKYCSLF-PMNHIIRGLI STITISRDVFLV-----------GVML-TTSAYMVIILFRHQRQ----CKHLHGISH--- ---LRASPEKRATQTILLLVF--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >38/39.4-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MFDLLNIENDIICKATSYLNRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------TYMIYS- LFYF--------WAFNLSFTINRIFYCGAYTNMSETNQ-LKVTKYCSLF-PMNHIIRGLI STITISRDVFLV-----------GVML-TTSAYMVIILFRHQRQ----CKHLHGISH--- ---LRASPEKRATQTILLLVF--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >38/39.3-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVFYV------------- ---QAGLGAL------------ANIFLLFFYTIIILC----H-----KPKPMDL-ISCQL -------TFIHIIMVITGWDIFTT------------DMFDLLNIENDIICKATAYLKRV- ---MRGLSICITCLLSVF-------QAVTISPNSS-LLG-KFKHKLK------KYTIYS- FFYF--------WAFNLSFTINRIFFCGAYTNVSETNQ-LKITKYCSIF-PMNHIINGLV STITTIRDVFLV-----------GVML-TTSTYMVIILSRHQRQ----CKHLHGISH--- ---LRASPEKRATQTILLLVFFYVV---LYWMDFIISSSAIHLWM----------YDPV- ----------------MLT------------------VQTFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DTR------I ----I-TMLKKYA--------------------------NV------------------- -------------------CHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >38/39.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NIFYF------------- ---QAGLGTL------------ANIFLLFFYTIIILC----H-----KPKLMDL-ISCQL -------TFIHIIMVITGWDIFTS------------DMFDLLNIENDIICKATSYLNRV- ---MRGLSICITCLLSVF-------QAVTISPNNS-LLA-KFKHKLK------KYTIYS- FFYF--------WAFNLSFTINRIFYCGAYTNMSETNQ-LKVTKYCSLF-PMNYITRGLI STIITLRDVFFV-----------GVML-TTSAYMVIILFRHQRQ----CKHLHGISH--- ---PRGSPERKATYIILLLVFFNVV---MY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >39.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVFYV------------- ---QAVLGTL------------ANIFLLFFYTIIILC----H-----RSKPMDL-ISCQL -------TFVHIMMFLTGGDIWLT------------DLFESLNIENNFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMISS- FFYI--------WSFNLLFIINRIFYTGAYTNVSDTNQ-LKVTKYCSLF-PMNNIIKGLA STIVTLRDVFLV-----------GVML-STSTYMVIILFRHQRQ----CKHLHSKSQ--- ---LRASPE--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal34-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MC------------------SKN-------S--WS------------- ---HQG-----------------------------------H-----RPKPTDL-ISCQL -------SFVHIMVVLIGGDILLA------------DIFESLNIGNDFKCKTTFYLFRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMISS- FFYF--------WSFNLSFSINHIIYTGAYTNVSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-V--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------YHQI---------F--------------------------- ------------------------------------------------------------ ------------- >36/37.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NILDF------------- ---QTGLGAI------------ANIFLLFFYTMIILC----H-----RSKPMDL-ISCQL -------TFSHIMMFLTGGHAWLK------------DFFGSMNIGNDFICKAIAYINRV- ---MRGLSICITCLLSVF-------QAVTISPNSS-LLA-KFKHKLK------TYMIYS- LFYF--------WSFNLSFSSNRIFYTGAYTNVSETNQ-LKVTKYCSLF-PMNYIIKGLI LTMTTLRDVFLV-----------GVML-TTSMYMVIILFRHQRQ----CKHLHSISQ--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISSSSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-MMLKNMQ--------------------------KL------------------- -------------------CHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >36/37.3-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MIYS- LFYF--------WSFNLSFSINRIIYTGAYTNVSETSQ-LKVTKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISQ--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISSSSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-MMLKNMQ--------------------------KL------------------- -------------------CHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >35.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NILYF------------- ---QAGLGAI------------ANIVLLFFYTIIILC----H-----RSKPMDM-ISCQL -------TFIHIMLFLTGGHAWLT------------DFFVSLNIGNDFICKATAYINRV- ---MRGLSICITCLLSVF-------QAVTISPNNS-LLA-KFKHKLK------KYMIYS- FFYF--------WSLNLSFSINHIIYTGAYTNVSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTSRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------LKKV------------------------ ------------------------------------------------------------ ------------- >35-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDM-ISCQL -------TFIHIMMFLTGGQVWLT------------DFFVSLNIGNDFICKATAYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIIYTGAYTNVSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >37.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MNYIIRGLI LTMTTLRDVFLV-----------GVML-TMSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------F--------------------------- ------------------------------------------------------------ ------------- >37.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NILNF------------- ---QTGLGAI------------ANIFLLFFYTMIILC----H-----RSKPMDM-ISFQL -------TFIHIMMFLTGGHAWLK------------DFLGSLNIGNDFICKATAYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIIYTGAYTNVSETNQ-LKVTKSCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TMSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------F--------------------------- ------------------------------------------------------------ ------------- >37.3-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDM-ISFQL -------TFIHIMMFLTGGHAWLK------------DFLGSLNIGNDFICKATAYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIIYTGAYTNVSETNQ-LKVTKSCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TMSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------F--------------------------- ------------------------------------------------------------ ------------- >36/37-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NILNF------------- ---QTGLGAI------------ANIFLLFFYTMIILC----H-----RSKPMDL-ISFQL -------TFIHIMMFLTGGHAWLK------------DFLGSLNIGNDFICKATAYINRV- ---MRGLSICITCLLSVF-------QAVMISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIIYTGAYTNVSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >36/37-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NILNF------------- ---QTGLGAI------------ANIFLLFFYTMIILC----H-----RSKPMDL-ISFQL -------TFIHIMMFLTGGHAWLK------------DFLGSLNIGNDFICKATAYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIIYTGAYTNVSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >36.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NILNF------------- ---QTGLGAI------------ANIFLLFFYTMIILC----H-----RSKPMDM-ISFQL -------TFIHIMMFLTGGHAWLK------------DFLGSLNIGNDFICKATAYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSLNLSFSINHIIYTGAYINGSETNQ-LKVTKSCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TMSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------EKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >36.3-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDM-ISFQL -------TFIHIMMFLTGGHAWLK------------DFLGSLNIGNDFICKATAYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSLNLSFSINHIIYTGAYINGSETNQ-LKVTKSCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TMSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------EKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >34-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NILNF------------- ---QTGLGAI------------ANIFLLFFYTMIILC----H-----RSKPMDM-ISCQL -------TFIHTMMCLTGGNVWLT------------DLLGSLNIVNDFICKATFYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIIYTGAYTNVSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >35.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NILYF------------- ---QAGLGAI------------ANIVLLFFYTIIILC----H-----RSKPMDM-ISCQL -------TFIHIMLFLTGGHAWLT------------DFFVSLNIGNDFICKATAYINRV- ---MRGLSICITCLLSVF-------QAVTISPNNS-LLA-KFKHKVK------KYMISS- FFYF--------WSFNLSFSINRIIYTGAYTNVSETSQ-LKVIKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----S-MMLKNMQ--------------------------K-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >35.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NILYF------------- ---QAGLGAI------------ANIVLLFFYTIIILC----H-----RSKPMDM-ISCQL -------TFIHIMLFLTGGHAWLT------------DFFVSLNIGNDFICKATAYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMISS- FFYF--------WSFNLSFSINRIIYTGAYTNVSETSQ-LKVIKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATHTILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----S-MMLKNMQ--------------------------K-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >35.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATHTILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----S-MMLKNMQ--------------------------K-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal33-p ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------M-- --------HFPIMF------------------SLN-------NVLYF------------- ---QAGLGTL------------ANIFLLFFYTIIILC----H-----RSKPMDL-ISCQL -------TFVHIMMFLTGGDIWLT------------DLFESLNIENDFICKATFYINRV- ---MRGLSICITCLLSVF-------QAVTISPNSS-LLA-KFKHKLK------KYMIFS- FFYF--------WSFNLSFSSNRIFYVGAYTNVSETNQ-LKVTKYCSLF-PINHIIRGLI LTITTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISQ--- ---LRASPEKRATQTILLLVIFFVV---MYWMDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVLN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISA-------DNR------M ----I-ITLKNMQ--------------------------KI------------------- -------------------CHQI---------FLKG-SHP-------------------- ------------------------------------------------------------ ------------- >basal34-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIIYTGAYTNMSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTSRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISH--- ---LRASPEKRATQIILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------M ----I-ITLKNMQ--------------------------KI------------------- -------------------CHQI---------FKKG------------------------ ------------------------------------------------------------ ------------- >basal33.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MY---------------------------------------------- -----------------------------FYN--ILCREEIH-----R------------ ------------------------------------EIYQ--NIGNDVQYGTSKFRDRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIFS- FFYF--------WSFNLSFSSNRIFYVGAYTNMSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTSRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISH--- ---LRASPEKRATQIILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------M ----I-ITLKNMQ--------------------------KI------------------- -------------------CHQI---------FKKG------------------------ ------------------------------------------------------------ ------------- >basal33.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVLYF------------- ---QVGLGTL------------ANIFLLFFYTVIILC----H-----RSKPMDL-ISCQL -------TFVHIMMFLTGGDIWLT------------DLFESLNIENDFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIFS- FFYF--------WSFNLSFSSNRIFYVGAYTNMSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTSRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISH--- ---LRASPEKRATQIILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------M ----I-ITLKNMQ--------------------------KI------------------- -------------------CHQI---------FKKG------------------------ ------------------------------------------------------------ ------------- >32-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVLYF------------- ---QVGLGTL------------ANIFLLFFYTIIILC----H-----RSKPMDL-ISCQL -------TFVHIMMFLTGGDIWLT------------DLFESLNIENDFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIFS- FFYF--------WSFNLSFSSNRIFYVGAYTNMSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTSRDVFLV-----------GVML-TTSAYMVIILFRHQRQ----CKHLHSNSH--- ---LRASPEKRATQIILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------IIS-------DNR------M ----I-ITLKNMQ--------------------------KI------------------- -------------------CHQI---------F--------------------------- ------------------------------------------------------------ ------------- >basal33-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NVLYF------------- ---QVGLGTL------------ANIFLLFFYTVIILC----H-----RSKPMDL-ISCQL -------TFVHIMMFLTGGDIWLT------------DLFESLNIENDFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVMISPNTS-LLA-KFKHKLK------KYMIYS- FFYF--------WSFNLSFSINRIFYTGAYTNMSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTSRDVFLV-----------GVML-TTSAYMVIILFRHQRQ----CKHLHSNSH--- ---LRASPEKRATQIILLLVVFFVV---MYWVDFII------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal33-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NILYF------------- ---QTGLGVL------------ANMFLLTFYIFTIPC----H-----SPKPVHL-MSCQL -------TFIHIIMVLTGWDIWLT------------DMFELLNIENDFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMIFS- FFYF--------WSFNLSFSINRIFYTGAYTNMSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSNSH--- ---LRASPEKRATQIILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DNR------M ----I-ITLKNMQ--------------------------KI------------------- -------------------CHQI---------F--------------------------- ------------------------------------------------------------ ------------- >36.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------M-VSKGL -------VIIKIL----------------------------------------------- --------ICIKKKPSNS-------KTESLSGH--------------------------- ------------------HCINHIIYTGAYINGSETNQ-LKVTKSCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TMSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------EKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >36-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------M-VSKGL -------VIIKIL----------------------------------------------- --------ICLKTKNSNS-------KTESLSGH--------------------------- ------------------HCINRIIYTGAYTNVSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IILKSMQ--------------------------KL------------------- -------------------WHQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >36/37.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MIYS- LFYF--------WSFNLSFCINRIFYTGAYTNMSETNQ-LKVTKYCSLF-PMNYIIKGLI LTMTTLRDVFLV-----------GVML-TTSMYMVIILFRHQRQ----CKHLHSISQ--- ---LRASPEKRATQTILLLVFFFVV---MYWVDFIISSSSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-MMLKIMP--------------------------PD------------------- -------------------F---------------------------------------- ------------------------------------------------------------ ------------- >34-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLN-------NILYF------------- ---QAGLGAM------------ANIFLLFFYTMIILC----H-----RSKPMDM-ISCQL -------TFVHTMMCLTGGNVWLT------------DLLGSLNIVNDFICKATFYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKYKLK------KYMISS- FFYF--------WSFNLSFSINRIFYAGAYTNVSETNQ-LKVTKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISH--- ---FRASPEKRATQTILLLLVFFVV---MYWVDFIISSSSVLLWM----------YDPV- ----------------MLT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-IQ-KKCK--------------------------NY------------------- -------------------ASRY---------FKKC-NFPLI------------------ ------------------------------------------------------------ ------------- >34-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MHH- FLYLK-------YASSMCLSINRIIYTGAYTNVSETNQ-LKVIKYCSLF-PMNYIIRGLI LTMTTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----S-MMLKICK--------------------------NY------------------- -------------------ATRF---------LKKC-NFLLI------------------ ------------------------------------------------------------ ------------- >11-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NALYI------------- ---QAGLGVL------------ANMFLLVFYIFIILG----H-----RPKPMDL-ISCQQ -------TFIHIMLFFTAGDILHT------------DIFESLNIENDFKCKTTFYICRV- ---MRGLSICTTCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYTINA- FFYI--------WSFNLSFSSNLIFYVGAYSNVSETNQ-MKVTKHCSLF-PMNYITRGLI LSVTTSRDVFLV-----------GVML-ITSTYMVIILFRHQRQ----CKHLHSISH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSSSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-NSLKNLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >11.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF---------------------------------------------- --------------------------------FKGPG----H-----RPKPMDL-ISCQQ -------TFIHIMLFFTAGDILHT------------DIFESMNIENDFKCKTTFYICRV- ---MRGLSICTTCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYTINA- FFYI--------WSFNLSFSSNLIFYVGAYTNVSETNQ-MKVTKYCSLF-PMNYIIRGLI LTVTTSRDVFLV-----------GVML-ITSTYMVIILCRHQRQ----CKHLHSISH--- ---LRASPEKKATQTILLLVIYFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------VLT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-NLLKNLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >11.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-ISCQQ -------TFIHIMLFFTAGDILHT------------DIFESMNIENDFKCKTTFYICRV- ---MRGLSICTTCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYTINA- FFYI--------WSFNLSFSSNLIFYVGAYTNVSETNQ-MKVTKYCSLF-PMNYIIRGLI LTVTTSRDVFLV-----------GVML-ITSTYMVIILFRHQRQ----CKHLHSIRH--- ---LRASPEKKATQTILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-NLLKNLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >11.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NALYI------------- ---QAGLGVL------------ANMCLLVFYIFIILG----H-----RPKPMDL-ISCQQ -------TFIHIMLFFTAGDILHT------------DIFESMNIENDFKCKTTFYICRV- ---MRGLSICTTCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYTINA- FFYI--------WSFNLSFSSNLIFYVGAYTNVSETNQ-MKVTKYCSLF-PMNYIIRGLI LTVTTSRDVFLV-----------GVML-ITSTYMVIILFRHQRQ----CKHLHSIRH--- ---LRASPEKKATQTILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-NLLKNLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >11-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NALYI------------- ---QAGLGVL------------ANMCLLVFYIFIILG----H-----RPKPMDL-ISCQQ -------TFIHIMLFFTAGDILHT------------DIFESMNIESDFKCKTTFYICRV- ---MRGLSICTTCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYTINA- FFYI--------WSFNLSFSSNLIFYVGAYTNVSETNQ-MKVTKYCSLF-PMNYIIRGLI LTVTTSRDVFLV-----------GVML-STSTYMVIILFRHQRQ----CKHLRSNSH--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-NLLKNLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >11-z -M---------------------------------------------------------- ---------------------------LE------------------------------- --------------------------------------------------DRRPLASA-- --------SLSLMF------------------SLE-------NALYI------------- ---QAGLGVL------------ANMCLLVFYIFIILG----H-----RPKPMDL-ISCQQ -------TFIHIMLFFTAGDILHT------------DIFESMNIENDFKCKTTFYICRV- ---MRGLSICTTCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYTINA- FFYI--------WSFNLSFSSNLIFYVGAYSNVSETNQ-MKVTKYCSLF-PMDYIIRGLI LTVTTSRDVFLV-----------GVML-ITSTYMVIILFRHQRQ----CKHLHSIRQ--- ---LRASPEKKATQTILLLVIFFVV---MYWVDFIISTTSVLLWI----------YDPV- ----------------SLM------------------VQKFLMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------IGS-------DNR------I ----I-IMVKNMY--------------------------SK------------------- -------------------HH--------------------------------------- ------------------------------------------------------------ ------------- >11-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NVLYI------------- ---QAGLGVL------------ANMFLLVFYIFIILG----H-----RPKPMDL-ISCQL -------TFIHIMLFFTAGDILHR------------DIFETLNIENDFKCKITFYICRV- ---MRGLSICTTCLLSVF-------QAVTISPNTS-LLA-KFKHKLK------KYMTNA- FFYI--------WSFNLFFSSNLIFYVGAYTNVSETNQ-MKVTKYCSLF-PINHIIRGLI LTITTLRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISQ--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISFTSILLWV----------YDPV- ----------------VLT------------------VQMFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-NLLKNLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >13-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MFLLIFYIFIILG----H-----RPKPIDL-ISCQL -------TFVHILMILTGGNVMLT------------DIFESLNVENDFKCKTIFYISRV- ---MRGLSISTTCLLSVI-------QAVTISPSTS-MLA-KFKHKLR------KHMVNAS FFYI--------WSFNFSLSSILIFYTGGFTNVSETKQ-MKITKSCSIL-PMNYIIRGMV VTVTTIRDVFLV-----------GVML-ITSIYMVIILFRHQRQ----CKHLHSINH--- ---LRESPEKRATQTILLLVVFFVV---MYWVDFILSSTSVTLWT----------YDPV- ----------------ILT------------------VQKFLMN---------------- ---A--YP-----------------------I-I--T---P--------------LL--- --------Q-------------------------------ISS-------DKR------V ----I-NVLKTLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >13-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NVLYF------------- ---QAGFGFL------------ANMFLLVFYIFIILG----H-----RPKLIDL-ISCQL -------TFVHILMILTGGNVMLT------------DIFESLNVENDIKCKATLYTNRV- ---MRGLSISITCLLSVI-------QAVTISPSTS-MLA-KFKHKLR------KHMVNAS FFYI--------WSFNFSLSSILIFYTGGFTNVSETKQ-MKITKSCSIL-PMNYIIRGMV VTVTTVRDVFLV-----------GVML-ITSAYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFILSSTSVTLWM----------YDPV- ----------------ILT------------------VQKFLMN---------------- ---A--YP-----------------------I-I--T---P--------------LL--- --------Q-------------------------------ISS-------DKR------V ----I-NVMKTLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >13-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NVLYF------------- ---QAGLGFI------------ANMFLLVFYIFIILG----H-----RPKLIDL-ISCQL -------TFVHILMILTGGNVMLA------------DIFESLNVENDIKCKATLYTNRV- ---MRGLSISITCLLSVI-------QAVTISPSTS-MLA-KFKHKLR------KHMVNAS FFYI--------WSFNFSLSSILIFYTGGFTNVSETKQ-MKITKSCSIL-PMNYIIRGMV VTVTTVRDVFLV-----------GVML-ITSAYMVIILFRHQRQ----CKHLHSINN--- ---LRTSPEKRATQTILLLVVFFVV---LYWVDFILSSTSVTLWM----------YDPV- ----------------ILT------------------VQKFLMN---------------- ---A--YP-----------------------I-I--T---P--------------LL--- --------Q-------------------------------ISS-------DKR------V ----I-NVMKTLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >13-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NILYF------------- ---QAGLGFL------------ANMFLLVFYIFIILG----H-----RPKLIDL-ISCQL -------TFVHILMILTGGNVMLT------------DIFESLNVENDIKCKATLYTNRV- ---MRGLSISITCLLSVI-------QAVTISPSTS-MLA-KFKHKLR------KHMVNAF FFYI--------WSFNFSLSSILIFYTGGFTNVSETKQ-MKITKSCSIL-PMNYIIRGIV VTVTTVRDVFLV-----------GVML-ITSAYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFILSSTSVTLWM----------YDPV- ----------------ILT------------------VQKFLMN---------------- ---T--YP-----------------------I-I--T---P--------------LL--- --------Q-------------------------------ISS-------DKR------V ----I-NVMKTLQ--------------------------SK------------------- -------------------CY--------------------------------------- ------------------------------------------------------------ ------------- >13-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NILYF------------- ---QAGLGFL------------ANMFLLVFYIFIILG----H-----RPKLIDL-ISCQL -------TFIHILMILTGGNVMLT------------DIFESLNVENDIKCKATLYTNRV- ---MRGLSISITCLLSVI-------QAVTISPSTS-MLA-KFKHKLR------KHMVNAF FFYI--------WSFNFSLSSILIFYTGGFTNVSETKQ-MKITKSCSIL-PMNYIIRGIV VTVTTVRDVFLV-----------GVML-ITSAYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFILSSTSVTLWM----------YDPV- ----------------ILT------------------VQKFLMN---------------- ---T--YP-----------------------I-I--T---P--------------LL--- --------Q-------------------------------ISS-------DMR------V ----I-NVMKTLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >13-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MRGLSICITCLLSVI-------QAVTISPSTS-ILA-KFKHKLR------KHMVNAS FFYI--------CSFNFSLSSILIFYVGGFTNMSETKQ-MKITKSCLIL-PMNYIIRGMV VTVTIVRDVFFV-----------GVML-ITSTYMVIILFRHQRQ----CQHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFILSSSSVLLWM----------YDPV- ----------------VLI------------------VQKFVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------L ----I-NVLKTLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >244-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ML------------------SIQ-------NVLYF------------- ---QAGLGVL------------ANMFLVCFYIYIILC----H-----RPKSTDM-ISCQL -------TFVHIIMLLTGGNIWLT------------DIFESLNIENGFICKATFYISRV- ---MRGLSMCITCLLSVF-------QAVTISPSTS-LLA-KFKQKLK------KYMIYS- FLCI--------WFFNLSFNSNQIFYVGAYTNVSGTNQ-MKATKSCSLL-PMNYIIRGLI LTVTTSRDMFLV-----------GVML-TTSTYMVIILFRHQRQ----CKYLHSISH--- ---PRASPEKKATQTILLLVVCFVV---MYWVDFIISMTSFLLWM----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISF-------DSR------I ----I-IMLKKLQ--------------------------SK------------------- -------------------YHHT---------FF-------------------------- ------------------------------------------------------------ ------------- >244-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------PIQ-------NVLYF------------- ---QAGLGVL------------ANMFLVCFYIYIILC----H-----KPKSTDM-ISCQL -------TFVHIIMLLTGGNIWLT------------DIFESLNIENGFICKATFYISRV- ---MRGLSMCITCLLSVF-------QAVTISPSTS-LLA-KFKQKLK------KYMIYS- FLCI--------WFFNLSFNSNQIFYVGAYTNVSGTNQ-MKATKSCSLL-PMNYIIRGLI LTVTTSRDMFLV-----------GVML-TTSTYMVIILFRHQRQ----CKYLHSISH--- ---LRASPEKKATQTILLLVVCFVV---MYWVDFIISMTSFLLWR----------YDSV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISF-------DSR------I ----I-IMLKKIQ--------------------------SK------------------- -------------------YHHT---------FLKK-RCLIS-----------------S L---------------KTI-F--------------------------------------- ------------- >244-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SIQ-------NVLYF------------- ---QAGLGVL------------ANMFLVCFYIYIILC----H-----KPKSTDM-ISCQL -------TFVHIIMLLTGGNIWLT------------DIFESLNIENGFICKATFYISRV- ---MRGLSMCITCLLSVF-------QAVTISPSTS-LLA-KFKQKLK------KYMIYS- FLCI--------WFFNLSFNSNQIFYVGAYTNVSGTNQ-MKATKSCSLL-SMIYIIRGLI LTVTTSRDMFLV-----------GVML-TTSTYMVIILFRHQRH----CKYLHSINH--- ---LRASPEKKATQTILLLVVCFVV---MYWVDFIISMTSFLLWM----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISF-------DSR------I ----I-IMLKKLQ--------------------------SK------------------- -------------------YHHT---------FFKK-RCLIS-----------------S L---------------KTI-F--------------------------------------- ------------- >244.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SIK-------NVLYF------------- ---QAGLGVL------------ANMFLVCFYIYIILG----H-----RPKFTDM-ISCQL -------TFVHIIMLFTGGDIWLT------------DIFESLNIENGFKCKATFYISRV- ---MRGLSMCITCLLSVF-------QAVTISPSTS-LLA-KFKQKLK------KYMIYF- FLCI--------WSFNLFFTSNQIFYVGAYINVSGTNQ-MKATKHCSLL-PMNYIIRGLI LTVTTSRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSANH--- ---LRASPEKRATQAILLLVVCFVA---MYWVDFIISMTSFLLWM----------YDSV- ----------------ILT------------------VQKFLMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISF-------DSR------I ----I-IMLKKLE--------------------------SK------------------- -------------------HRHT---------FF-------------------------- ------------------------------------------------------------ ------------- >244.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SIK-------NVLYF------------- ---QAGLGVL------------ANMFLVCFYIYIILG----H-----RPKFTDM-ISCQL -------TFVHIIMLFTGGDIWLT------------DIFESLNIENGFICKATFYISRV- ---MRGLSMCITCFLSVF-------QAVTISPSTS-LLA-KFKQKPK------KYMIYF- FLCI--------WSFNLFFTSNQIFYVGAYINVSGTNQ-MKATKHCSLL-PMNYIIRGLI LTVTTSRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSANH--- ---LRASPEKRATQAILLLVVCFVA---MYWVDFIISMTSFLLWM----------YDSV- ----------------ILT------------------VQKFLMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISF-------DSR------I ----I-IMLKKLE--------------------------SK------------------- -------------------HRHT---------FF-------------------------- ------------------------------------------------------------ ------------- >5-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SIK-------NVLYF------------- ---QAGLGVL------------ANMFLVCFYIYIIVC----H-----RSKPTDL-ISCQL -------TFVHIIMFLTGGDIWLT------------DLFELLNIENDIKCKTTFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPNTT-SLA-KFKHKLK------KYMIYA- FLCM--------WSFNLSFSTNQIFFVGAYTNVSETEQ-MKATKYCSLL-PMNNIIRGLI LTVTTSRDVFLV-----------GVML-TTSTYMVIILSRHQRQ----CKHLHSISH--- ---LSASPEKRATQTILLLVFFFVV---MYWVDFIISTTSFLLWM----------YDPV- ----------------ILT------------------LQKFLMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISF-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HHHI---------YF-------------------------- ------------------------------------------------------------ ------------- >5-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SIK-------NVLYF------------- ---QAGFGVL------------ANMFLVCFYIYIILG----H-----RPKPTDL-ISCQL -------TFVHIIMFLTGGDIWLT------------DFFELLNIENDIKCKATFYISRV- ---MRGLSMCTTCLLSVY-------QAVTICPSTI-LLA-KFKHKLK------KYMIYA- FLCM--------WSFNLSFNSNQIFFVGAYTNASETQQ-MKATKYCSLL-PMNNIIRGLI LTVTTSRDVFLI-----------GVML-TTSTYMVIILSRHQRQ----CKHLHSISH--- ---MRASPEKRATQTILLLVFFFVA---MYWVDFIISTTSFLLWR----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------FSS-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HHHM---------YFKKYIFTLL------------------ ------------------------------------------------------------ ------------- >5-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SIK-------NVLYF------------- ---QAGFGVL------------ANMFLVCFYIYIILG----H-----RPKPTDL-ISCQL -------TFVHIIMFLTGGDIWLT------------DFFELLNIENDIKCKATFYISRV- ---MRGLSMCTTCLLSVY-------QAVTICPSTT-LLA-KFKHKLK------KYMIYA- FLCM--------WSFNLSFNSNRIFFVGAYTNASETQQ-MKATKYCSLL-PMNNIIRGLI LTVTTSRDVFLI-----------GVML-TTSTYMVIILSRHQRQ----CKHLHSISH--- ---MRASPEKRATQTILLLVFFFVA---MYWVDFIISTTSFLLWR----------YDPV- ----------------ILT------------------IQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------FSS-------DNR------I ----I-IMVKNL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >5-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SIK-------NVLYF------------- ---QAGFGVL------------ANMFLVCFYIYIILG----H-----RPKPTDL-ISCQL -------TFVHIIMFLTGGDIWLT------------DFFELLNIENDIKCKATFYISRV- ---MRGLSMCTTCLLSVY-------QAVTICPSTT-LLA-KFKHKLK------KYMIYA- FLCM--------WSFNLSFNSNRIFFVGAYTNVSETQQ-MKATKYCLLL-PMNNIIRGLI LTVTTSRDVFLI-----------GVML-TTSTYMVIILSRYQRQ----CKHLHSISH--- ---MRASPEKRATQTILLLVFFFVA---MYWVDFIISTTSFLLWR----------YDPV- ----------------ILT------------------IQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------FSS-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HHHM---------YF-------------------------- ------------------------------------------------------------ ------------- >5-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SIK-------NVLYF------------- ---QAGFGVL------------ANLFLVCFYIYIILG----H-----RRKPTDL-ISCQL -------TFVHIIMFLTGGDIWLT------------DFFELLNIENDIKCKATFYISRV- ---MRSLSMCTTCLLSVF-------QAVTICPSTT-LLA-KFKHKLK------KYMIYA- FLCM--------WSFNLSFNSNQIFFVGAYTNVSETKQ-MKATKYCSLL-PMNNIIRGLI LTVTTSRDVFLI-----------GVML-TTSTYMVIILSRHQRQ----CKHLHSISH--- ---MRASPEKRATQTILLLVFFFVV---MYWVDLIISMTSFLLWR----------YDPV- ----------------ILT------------------VQKFLMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------FSS-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HHHM---------YFKKYVFTLLYK--------------TY ------------------------------------------------------------ ------------- >6.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMFLVCFYIYIILG----H-----RPKPTDL-ISCQL -------TLVHIMMFLTGGDVWLT------------DLFESLNIENDFKCKAIFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPNTT-FLA-KYKQKLK------NYMIYA- FLCM--------WSFNLSFTSNRIFFVGAYTNVSETKQ-MKATKYCSLL-PMNNIIRGVI LTVTTSRDVFLV-----------GAML-TTSTYMVIILSRHQRQ----CKHLHSISH--- ---MRASPEKRATQTILLLVVFFVV---MYWVDFIISTTSFLLWR----------YDPV- ----------------ILT------------------LQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------VSF-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HYHL---------YF-------------------------- ------------------------------------------------------------ ------------- >6.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMFLVCFYIYIILG----H-----RPKPTDL-ISCQL -------TLVHIMMFLTGGDVWLT------------DLFESLNIENDFKCKATFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPNTT-FLA-KYKQKLK------NYMIYA- FLCM--------WSFNLSFTSNRIFFVGAYTNVSETKQ-MKATKYCSLL-PMNNIIRGVI LTVTTSRDVFLV-----------GAML-TTSTYMVIILSRHQRQ----CKHLHSISH--- ---MRASPEKRATQTILLLVVFFVV---MYWVDFIISTTSFLLWR----------YDPV- ----------------ILT------------------LQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------VSF-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HYHL---------YF-------------------------- ------------------------------------------------------------ ------------- >6.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLK-------NVLYF------------- ---QAGFGVL------------ANMFLVCFYIYIILG----H-----RPKPTDL-ISCQL -------TLVHIMMFLTGGDVWLT------------DLFESLNIENDFKCKATFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPNTT-FLA-KYKQKLK------NYMIYA- FLCM--------WSFNLSFSSNRIFFVGAYTNVSETKQ-MKATKYCSLL-PMNNIIRGVI LTVTTSRDVFLV-----------GAML-TTSTYMVIILSRHQRQ----CKHLHSINH--- ---MRASPEKRATQTILMLVVFFVV---MYWVDFIISTTSFLLWR----------YDPV- ----------------ILT------------------LQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------VSF-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HYHL---------YF-------------------------- ------------------------------------------------------------ ------------- >6.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------M-------HLNYF------------- ---R------------------------------LSG----H-----RPKPTDL-ISCQL -------TLVHIMMFLTGGDVWLT------------DLFESLNIENDFKCKATFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPNTT-FLA-KYKQKLK------NYMIYA- FLCM--------WSFNLSFSSNRIFFVGAYTNVSETKQ-MKATKYCSLL-PMNNIIRGVI LTVTTSRDVFLV-----------GAML-TTSTYMVIILSRHQRQ----CKHLHSINH--- ---MRASPEKRATQTILMLVVFFVV---MYWVDFIISTTSFLLWR----------YDPV- ----------------ILT------------------LQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------VSF-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HYHL---------YF-------------------------- ------------------------------------------------------------ ------------- >6-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLK-------NVLYF------------- ---QSGLGVL------------ANMFLVCFYIYIILG----S-----RPKPTDL-ISCQL -------TLVHIMMFLTGGDVWLT------------DLFESLNIENNFKCKATFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPNTT-FLA-KYKQKLK------NYMIYA- FLCM--------WSFNLSFSSNRIFFVGAYTNASETQQ-MKATKYCSLL-PMNNIIRGLI LTVTTSRDVFLI-----------GVML-TTSTYMVIILSRHQRQ----CKHLHSISH--- ---MRASPEKRATQTILLLVVFFVV---MYWVDFIISTTSLLLWR----------YDPV- ----------------ILT------------------LQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------VSF-------DNR------I ----I-IMLKNIR--------------------------SKTTIYIF------------- -----------------KNMFLL---------FFQN-LLIFSY---------------LY V---------------HGL-FYSACLYA--F--PC-AHRGEK-I---------------- ----SWHPMELDL >17/31-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------AFK-------NVLYF------------- ---QAGLGVL------------ANMFLLCFYIFILIG----H-----RPKPMDL-ISCQL -------SFIHMMMFLTGGDLLLT------------DIFASLNIDNDFKCKATFYISRV- ---TRGLSICTTCLLSVF-------QAVTISPNTS-VLA-NFKQKLK------KYMIYV- FLCI--------WSFNLSYSSNRIFYVRGFTNVSETNQ-MQVTESCSLF-RMNYIIRVFI FTVTTSRDVFLV-----------GVML-ITSTYMVIILCRHQRQ----CKHLHSIKH--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFVISTISVLLWM----------YDPV- ----------------ILR------------------VQKFVMY---------------- ---A--FP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNMH--------------------------SK------------------- -------------------HHQR---------FFGD-FFLFL------------------ ------------------------------------------------------------ ------------- >17.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------AFK-------NVLYF------------- ---QAGLGVL------------ANMFLLCFYIFILIG----H-----RPKPTDL-ISCQL -------TFIHMMMFLTGGDLLLT------------DIFSSLNIDNDFKCKTTFYISRV- ---TRGLSICTTCLLSVF-------QAVTISPKTS-VLA-NFKQKLK------KYMTYV- FLCI--------WSFNLSYSSNRIFYVHGFTNVSETNQ-MQVTESCSLF-RMNYIIRVFI FTVTTSRDVFLV-----------GVML-ITSTYMVIILCRNQRQ----CKHLHSINH--- ---LRASPEKRATQAILLLVIFFVV---MYWVDFIISSTSVLLWM----------YDPI- ----------------ILQ------------------VQKFVMY---------------- ---A--FP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-VMLKNMH--------------------------SK------------------- -------------------HHQR---------FF-------------------------- ------------------------------------------------------------ ------------- >17.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MMMFLTGGDLLLT------------DIFSSLNIDNDFKCKTTFYISRV- ---TRGLSICTTCLLSVF-------QAVTISPKTS-VLA-NFKQKLK------KYMTYV- FLCI--------WSFNLSYSSNRIFYVHGFTNVSETNQ-MQVTESCSLF-RMNYIIRVFI FTVTTSRDVFLV-----------GVML-ITSTYMVIILCRNQRQ----CKHLHSINH--- ---LRASPEKRATQAILLLVIFFVV---MYWVDFIISSTSVLLWM----------YDPI- ----------------ILQ------------------VQKFVMY---------------- ---A--FP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-VMLKNMH--------------------------SK------------------- -------------------HHQR---------FF-------------------------- ------------------------------------------------------------ ------------- >17/31-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------TFK-------NVLYF------------- ---QTGLGVL------------ANMFLLCFYIFILIG----H-----RPKPTDL-ISCQL -------TFIHMMMFLTGGDLLLT------------EIFVSLNIDNDFKCKATFYISRV- ---TRGLSICTTCLLSVF-------QAVTISPNTS-LLA-NFKQKLK------KYMTYV- FLCI--------WSFNLSYSSNRIFYVRGFTNVSETNQ-MRVTESCSLL-RMNYIIRVLI FTVTTSRDVFLV-----------GVML-ITSTYMVIVLC--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >31-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------AFK-------NVLYF------------- ---QAGLGVL------------ANMFLLCFYIFILIG----H-----RPKPMDL-ISCQL -------SFIHMMMFLTGGDLLLT------------DIFASLNIDNDFKCKATFYISRV- ---TRGLSICTTCLLSVF-------QAVTISPNTS-VLA-NFKPKLK------KYMTYV- FLCI--------WSFNLSYSSNRFFYVHGFTNVSETNL-MQVTESCSLF-RMNYIIRGLM LTVSISRDVFLV-----------GIMM-TTSTYMVIILCRHQRQ----CKHLHSIRH--- ---LRASPEKKATQTILLLVIFFVV---MYWVDFIISSTSVLLWR----------YDPV- ----------------ILW------------------VQKFVMY---------------- ---A--FP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNMH--------------------------SK------------------- -------------------HHQR---------FFGD-FFLFL------------------ ------------------------------------------------------------ ------------- >31-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------AFK-------NVLYF------------- ---QAGLGAL------------ANMFLLCFYIFIFIG----H-----RPKPTDL-ISCQL -------TFIHMMMFLTGGDLLLT------------DIFATLSIENDVKCKATFYISRV- ---TRGLSICTTCLLSVF-------QAITISPNTS-MLA-NFKPKLK------KYMTYV- FLCI--------WSFNLSYSSNRFFYVHGFTNVSETNQ-MQVTESCSLF-PMNYIIRGLM LTVSICRDVFLV-----------GIMM-TTSTYMVIILCRHQRQ----CKHLHSISH--- ---LRASPEKRATQAILLLVIFFVV---MYWVDFIISSTSVLLWM----------YDPI- ----------------ILQ------------------VQKFVMY---------------- ---A--FP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNMH--------------------------SK------------------- -------------------HHQR---------FFLK-QF--------------------- ------------------------------------------------------------ ------------- >31.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------AFK-------NVLYF------------- ---QAGLGAL------------ANMFLLCFYIFIFIG----H-----RPKPTDL-ISCQL -------TFIHMMMFLTGGDLLLT------------DIFATLSIENDVKCKATFYISRV- ---TRGLSICTTCLLSVF-------QAVTISPNTS-MLA-NFKPKLK------KYMTYV- FLCI--------WSFNLSYSSNRFFYVHGFTNVSENNQ-MQVTESCSLF-PMNYIIRGLM LTVSICRDVFLV-----------GIMM-TTSTYMVIILCRHQRQ----CKHLHSISH--- ---LRASPEKRATQAILLLVIFFVI---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILR------------------VQKFVMY---------------- ---A--FP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNMH--------------------------SK------------------- -------------------HHQS---------FF-------------------------- ------------------------------------------------------------ ------------- >31.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MMMFLTGGDLLLT------------DIFATLSIENDVKCKATFYISRV- ---TRGLSICTTCLLSVF-------QAVTISPNTS-MLA-NFKPKLK------KYMTYV- FLCI--------WSFNLSYSSNRFFYVHGFTNVSENNQ-MQVTESCSLF-PMNYIIRGLM LTVSICRDVFLV-----------GIMM-TTSTYMVIILCRHQRQ----CKHLHSISH--- ---LRASPEKRATQAILLLVIFFVI---MYWVDFIISSTSVLLWM----------YDPV- ----------------ILR------------------VQKFVMY---------------- ---A--FP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNMH--------------------------SK------------------- -------------------HHQS---------FF-------------------------- ------------------------------------------------------------ ------------- >31-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------AFK-------NVLYF------------- ---QAGLGAL------------ANMFLLCFYIFIFIG----H-----RPKPTDL-ISCQL -------TFIHMMMFLTGGDLLLT------------DIFATLSIENDVKCKATFYISRV- ---TRGLSICTTCLLSVF-------QAVTISPNTS-MLA-NFKPKLK------KYMTYV- FLCI--------WSFNLSYSSNRFFYVHGFTNVSETNQ-MQVTESCSLF-PMNYIIRGLI LTVAISRDVFLV-----------GLML-TTSTYMVIILCRHQRQ----CKHLHSISH--- ---LRASPEKRATQAILLLVIFFVV---MYWVDFIISSTSVLLWM----------YDPI- ----------------ILQ------------------VQKFVMY---------------- ---A--FP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNMH--------------------------SK------------------- -------------------HHQS---------FF-------------------------- ------------------------------------------------------------ ------------- >27-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMSLLCFYIFIIVG----H-----RPKPTDL-ISCQL -------TFIHIMVCLTGGDLLLT------------DIFESLNINNDFKCKATFYISRV- ---MRCLSICTTCLLSVF-------QAVTISPSTS-CLA-KFKQKLR------KYMVYI- FLCI--------WSFSFSYSSSRIFYVRGFTNVSESNQ-MQITKSCLLF-RMNSIIRVFI FTVTTSRDVFLV-----------G------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >20-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMSLLCFYIFIIVG----H-----RPKPTDL-ISCQL -------TFIHIMVFLTGGDLLLT------------DIFESLNINNDFKCKATFYISRV- ---MRCLSICTSCLLSVF-------QAVTISPSTS-CLA-KFKQKLR------KYMVYV- FLCI--------WSFSFSYSSSRIFYVRGFTNVSETNQ-MQITKSCLLF-RMNSIIRVFI FTVTTSRDVFLV-----------GMML-TTSTYMVIILCRHQRQ----CKHLHSIKH--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISTISVLLWR----------YDTV- ----------------ILR------------------VQKFLMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMVKNMY--------------------------SK------------------- -------------------HHQR---------FF-------------------------- ------------------------------------------------------------ ------------- >27.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVCLTGGDLLLT------------DIFESLNINNDFKCKATFYISRV- ---MRCLSICTTCLLSVF-------QAVTISPSTS-CLA-KFKQKLR------KYMVYV- FLCI--------WSFSFSYSSSRIFYVRGFTNVSETNQ-MQITKSCLLF-RMNSIIRVFI FTVTTSRDVFLV-----------GMML-TTSTYMVIILCRHQRQ----CKHLHSISH--- ---LRVSPEKRATQTILLLVIFFVV---MYWVDFIIST---------------------- ------------------------------------------------------------ -------------------------------T-I--S---P--------------LV--- --------Q-------------------------------IGS-------DNR------I ----I-IMVKNMY--------------------------SK------------------- -------------------HHQR---------FL-------------------------- ------------------------------------------------------------ ------------- >27.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ML------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMSLLCFYIFIIVG----H-----RPKPTDL-ISCQL -------TFIHIMVCLTGGDLLLT------------DIFESLNINNDFKCKATFYISRV- ---MRCLSICTTCLLSVF-------QAVTISPSTS-CLA-KFKQKLR------KYMVYV- FLCI--------WSFSFSYSSSRIFYVRGFTNVSETNQ-MQITKSCLLF-RMNSIIRVFI FTVTTSRDVFLV-----------GMML-TTSTYMVIILCRHQRQ----CKHLHSISH--- ---LRVSPEKRATQTILLLVIFFVV---MYWVDFIISTTSVLLWI----------YDPV- ----------------SLM------------------VQKFLMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------IGS-------DNR------I ----I-IMVKNMY--------------------------SK------------------- -------------------HHQR---------FL-------------------------- ------------------------------------------------------------ ------------- >27.2-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ML------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMSLLCFYIFIIVG----H-----RPKPTDL-ISCQL -------TFIHIMVCLTGGDLLLT------------DIFESLNINNDFKCKATFYISRV- ---MRCLSICTTCLLSVF-------QAVTISPSTS-CLA-KFKQKLR------KYMVYV- FLCI--------WSFSFSYSSSRIFYVRGFTNVSETNQ-MQITKSCLLF-RMNSIIRVFI FTVTTSRDVFLV-----------GMML-TTSTYMMIILCRHQRQ----CKHLHSIKH--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISTTSVLLWI----------YDPV- ----------------SLM------------------VQKFLMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------IGS-------DNR------I ----I-IMVKNMY--------------------------SK------------------- -------------------HHQR---------FL-------------------------- ------------------------------------------------------------ ------------- >27-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ML------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMSLLCFYIFIIVG----H-----RPKPTDL-ISCQL -------TFIHIMVCLTGGDLLLT------------DIFESLNINNDFKCKATFYISRV- ---MRCLSICTTCLLSVV-------QAVTISPSTS-CLA-KFKQKLR------KYMVYV- FLCI--------WSFSFSYSSSRIFYVRGFTNVSETNQ-MQITKSCLLF-RMNSIIRVFI FTVTTSRDVFLV-----------GVML-TTSTYMVIILCRHQRQ----CKHLHSIKH--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISTTSVLLWI----------YDPV- ----------------SLM------------------VQKFLMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------IGS-------DNR------I ----I-IMVKNMY--------------------------SK------------------- -------------------HHQR---------FL-------------------------- ------------------------------------------------------------ ------------- >27.1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ML------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMSLLCFYIFIIVG----H-----RPKPTDL-ISCQL -------TFIHIMVCLTGGDLLLT------------DIFESLNINNDFKCKATFYISRV- ---MRCLSICTTCLLSVF-------QAVTISPSTS-CLA-KFKQKLR------KYMVYV- FLCI--------WSFSFSYSSSRIFYVRGFTNVSETNQ-MQITKSCLLF-RMNSIIRVFI FTVTTSRDVFLV-----------GMML-TTSTYMMIILCRHQRQ----CKHLHSIKH--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISTTSVLLWI----------YDPV- ----------------SLM------------------VQKFLMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------IGS-------DNR------I ----I-IMLKNMH--------------------------SK------------------- -------------------HHQS---------FF-------------------------- ------------------------------------------------------------ ------------- >27.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVCLTGGDLLLT------------DIFESLNINNDFKCKATFYISRV- ---MRCLSICTTCLLSVF-------QAVTITPSTS-CLA-KFKQKLR------KYMVYV- FLCI--------WSFSFSYSSSRIFYVRGFTNVSETNQ-MQITKSCLLF-RMNSIIRVFI FTVTTSRDVFLV-----------GMML-TTSTYMVIILYRHQRQ----CKHLHSIKH--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISTTSVLLWI----------YDPV- ----------------SLM------------------VQKFLMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------IGS-------DNR------I ----I-IMVKNMY--------------------------SK------------------- -------------------HHQR---------FL-------------------------- ------------------------------------------------------------ ------------- >27.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMSLLCFYIFIIVG----H-----RPKPTDL-ISCQL -------TFIHIMVCLTGGDLLLT------------DIFESLNINNDFKCKATFYISRV- ---MRCLSICTTCLLSVF-------QAVTITPSTS-CLA-KFKQKLR------KYMVYV- FLCI--------WSFSFSYSSSRIFYVRGFTNVSETNQ-MQITKSCLLF-RMNSIIRVFI FTVTTSRDVFLV-----------GMML-TTSTYMVIILYRHQRQ----CKHLHSIKH--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISTTSVLLWI----------YDPV- ----------------SLM------------------VQKFLMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------IGS-------DNR------I ----I-IMVKNMY--------------------------SK------------------- -------------------HHQR---------FL-------------------------- ------------------------------------------------------------ ------------- >20/27-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SFK-------NVLYF------------- ---QAGVGVL------------ANMSLLCFYIFIIVG----H-----RPKPTDL-ISCQL -------SFIHIMVLLTGGDLLLT------------DIFESLNINNDFKCKATFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPSTS-CLA-RFKQKLR------KYLIYV- FLCI--------WSFSLSYSSSRIFYVRGFTNVSETNQ-MQVTKSCLLF-RMSSIIRVFI FTVTTSRDVCLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISH--- ---PRASPEKRATQTILLLVVFFVV---MFWVDFIISTTSVLLWM----------YDPV- ----------------SLM------------------VQKFLTY---------------- ---V--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMVKNMH--------------------------SK------------------- -------------------HHQI---------FF-------------------------- ------------------------------------------------------------ ------------- >9.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QAGLGVL------------ANMVLLLFYIFIILG----H-----RPKPTDL-ISCQL -------TFVHIIMVLIGGDILLT------------DIFELLNIENDFKCKAIFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPSTS-LLA-KFKQKLK------KYMVCV- FLCI--------WFFNLAFSTNRIFYVGGFTNVSETNQ-MQVTKFCSLL-PMNIITRGLI FTISTSRDVFLV-----------GVML-TTSVYMVITMFRYQRQ----CKYLYSISH--- ---LRESPEKRATQSILLLVSFFVL---MYWVDFIISFTSDTIWM----------YHPV- ----------------ILT------------------LQRFMMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----K-TMLKNLQ--------------------------SK------------------- -------------------HQLN---------FF-------------------------- ------------------------------------------------------------ ------------- >9.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QTGLGVL------------ANTVLLFFYVFIILG----H-----RPKPTDL-ISCQL -------TFVHIIMVLIGGDILLT------------DIFELLNIENDFKCKAIFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPSTS-LLA-KFKQKLK------KYMVCV- FLCI--------WFFNLAFSTNRIFYVGGFTNVSETNQ-MQVTKFCSLL-PMNIITRGLI FTISTSRDVFLV-----------GVML-TTSVYMVITMFRYQRQ----CKYLYSISH--- ---LRESPEKRATQSILLLVSFFVL---MYWVDFIISFTSDTIWM----------YHPV- ----------------ILT------------------LQRFMMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----K-TMLKNLQ--------------------------SK------------------- -------------------HQLN---------FF-------------------------- ------------------------------------------------------------ ------------- >9/10.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QAGLGVL------------ANMVLLLFYIFIILG----H-----RPKPTDL-ISCQL -------SFVHIIMVLTGGDILLT------------DLFELLNIENDFKCKTIFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPSTS-FLA-KFKQKLK------KYMVCV- FLCI--------WSFNLAFSTNRIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNYIIRGLI FTISISRDVFLV-----------GVML-TTSVYMVIILCRHQRQ----CKHLHSFSH--- ---LRESPEKRATQTIMLLVSFFVV---LYWMDFIISFTSEMLRM----------YDPV- ----------------ILT------------------LQKFMMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLK-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >9/10.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QAGLGVL------------ANMVLLLFYIFIILG----H-----RPKPTDL-ISCQL -------SFVHIIMVLTGGDILLT------------DLFELLNIENDFKCKTIFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPSTS-FLA-KFKQKLK------KYMVCV- FLCI--------WSFNLAFSTNRIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNIIIRGLI FTISTSRDVFLV-----------GVML-TTSVYMVIFLFKHQRQ----CKHLHSFSH--- ---LRESPEKRATQTIVLLVSFFVV---MYWVDFIISFTSDMIWM----------YDPL- ----------------ILT------------------LQKFMMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HQQR---------FFNK-DFFFSL----------------- ------------------------------------------------------------ ------------- >9-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QAGLGVL------------ANMVLLLFYIFIILG----H-----RPKPTDL-ISCQL -------TFVHIIMVLTGGDILLT------------DLFELLNIENDLKCKTIFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPSTS-FLA-KFKQKLK------KYMVCV- FLCI--------WSFNLAFSTNRIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNIIIRGLI FTISTSRDVFLV-----------GVML-TTSVYMVITMFRYHRQ----CKYLYSISH--- ---LRESPEKRATQTILLLVSFFVV---MYWVDFIISFTSDMIWM----------YDPL- ----------------ILT------------------VQKFMMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HQ--------------------------------------- ------------------------------------------------------------ ------------- >10-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QAGLGVL------------ANMVLLLFYIFIILG----H-----RPKPTDL-ISCQL -------TFVHIIMVLTGGDILLT------------DLFELLNIENDLKCKTIFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPNTS-LMA-KFKQKLK------KYMACV- FLCI--------WSFNLAFSTNRIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNIIIRGFI FTISTSRDVFLV-----------GVML-TTSVYMVITMFRYHRQ----CKYLYSISH--- ---LRESPEKRATQTIVLLVSFFVV---MYWVDFIISFTSDMIWM----------YDPL- ----------------ILT------------------VQKFMMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HQQR---------FFNK-DIFFSL----------------- ------------------------------------------------------------ ------------- >10-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QAGLGVL------------ANMVLLLFYIFIILG----H-----RPKPTDL-ISCQL -------TFVHIIMVLTGGDILLT------------DLFELLNIENDFKCKTIFYISRV- ---MRGLSICTTCLLSVF-------QAVTISPNTS-LLA-KFKQKLK------KYMVCV- FLCI--------WSFNLAFSTNRIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNIIIRGFI FTISTSRDVFLV-----------GVML-TTSVYMVITMFRYHRQ----CKYLHSISH--- ---LRESPEKRATQTILLLVSFFVV---MYWVDFIISFTSDMIWM----------YDPL- ----------------ILT------------------VQKFMMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HQQR---------FFNK-DFFFSL----------------- ------------------------------------------------------------ ------------- >7/8-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MTHV- FLCI--------WFFNFSFSTNQIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNYIIRGLI FTISTSRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTIVLLVSFFVV---LYWMDFIMSFTSDMLWM----------YDTV- ----------------ILT------------------LQKFMMY---------------- ---A--YP-----------------------T-V--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNIQ--------------------------SK------------------- -------------------HHLS---------FS-------------------------- ------------------------------------------------------------ ------------- >7-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MTHV- FLCI--------WFFNFSFSTNQIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNYIIRGLI FTISISRDVFLV-----------GVML-TTSVYMVIFLFRHQRQ----CKHLHSFSH--- ---LRESPEKRATQTIMLLVSFFVV---LYWMDFIISFTSEMLRM----------YDPV- ----------------ILT------------------LQKFMMY---------------- ---A--YP-----------------------T-V--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNIQ--------------------------SK------------------- -------------------HHHS---------FS-------------------------- ------------------------------------------------------------ ------------- >7-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MVVLIGGDILLA------------DIFESLNIGNDFKCKTTFYLFRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-VLA-KFKQKVK------KYMTHV- FLCI--------WFFNLSFSTNQIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNYIIRGLI FTISISRDVFLV-----------GVML-TTSVYMVIILCRHQRQ----CKHLHSFSH--- ---LRESPEKRATQTIMLLVSFFVV---LYWMDFIISFTSEMLRM----------YDPV- ----------------ILT------------------LQKFMMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLK-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >7-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QTGLGVL------------ANTVLLFFYVFIILG----H-----RPKPTDL-ISCQL -------SFVHIMVVLIGGDILLA------------DIFESLNIGNDFKCKTTFYLFRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-VLA-KFKQKVK------KYMTHV- FLCI--------WFFNLSFSTNQIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNYIIRGLI FTISISRDVFLV-----------GVML-TTSVYMVIFLFRHQRQ----CKHLHSFSH--- ---PRESPEKRATQTIMLLVSFFVV---LYWMDFIISFTSEMLRM----------YDPV- ----------------ILT------------------LQKFMMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNIQ--------------------------SK------------------- -------------------CHPS---------FSLK-DFFFFI----------------- ------------------------------------------------------------ ------------- >7-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QTGLGVL------------ANTVLLFFYVFIILG----H-----RPKPTDL-ISCQL -------SFVHIMVVLIGGDILLA------------DIFESLNIGNDFKCKTTFYLFRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKQKVK------KYMTHV- FLCI--------WFFNLSFSSNQIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNHIIRGLI FTISISRDVFLV-----------GVML-TTSVYMVIFLFRHQRQ----CKHLHSFSH--- ---LRESPEKRATQTIMLLVSFFVV---LYWMDFIISFTSEMLWM----------YDPV- ----------------ILT------------------LQKFMMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNIQ--------------------------SK------------------- -------------------CHPS---------FSLK-DFFFFI----------------- ------------------------------------------------------------ ------------- >8-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QTGLGVL------------ANTVLLFFYVFIILG----H-----RPKPTDL-ISCQL -------SFVHIMMVLIGGDILLA------------DIFESLNIGNDFKCKTTFYLFRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-VLA-KFKQKVK------KYMTHV- FLCI--------WFFNLSFSTNRIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNHITRGLI FTISISRDVFLV-----------GVML-TTSVYMVIFLFRHQRQ----CKHLHSFSH--- ---LRESPEKRATQTIVLLVSFFVV---MYWVDFIISFTSDMIWM----------YDPV- ----------------ILT------------------LQKFMMY---------------- ---A--YP-----------------------T-V--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNIQ--------------------------SK------------------- -------------------HHLS---------FS-------------------------- ------------------------------------------------------------ ------------- >7/8-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------NVLYF------------- ---QTGLGVL------------ANTVLLFFYVFIILG----H-----RPKPTDL-ISCQL -------SFVHIMVVLIGGDILLA------------DIFESLNIGNDFKCKTTFYLFRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LLA-KFKQKVK------KYMTHV- FLCI--------WFFNLSFSSNQIFYVGGFTNVSETNQ-MQVTKSCSLL-PMNIIIRGFI FTISTSRDVFLV-----------GVML-TTSVYMVITMFRYHRQ----CKYLYSISH--- ---LRESPEKRATQTIVLLVSFFVV---MYWVDFIISFTSDMIWM----------YDPL- ----------------ILT------------------VQKFMMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNLQ--------------------------SK------------------- -------------------HQ--------------------------------------- ------------------------------------------------------------ ------------- >7/8.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------TVLYF------------- ---QTGLGVL------------ANTVLLFFYIFIILG----H-----RPKPTDL-ISCQL -------AFVHIMMVLIGGDILLA------------DIFESLNIGNDFKCKTTFFLFRV- ---MRGLSICITCLLSVF-------QAVIISPNTS-LLA-KFKQKVK------KYMAHV- FLCI--------WFFNLSFSTNRIFYVGGFTNVSETTQ-MQVTKSCSLL-PMNYIIRGLI FTISTSRDVFLV-----------GVML-TTSVYMVIFLFRHQRQ----CKHLHGINH--- ---LRESPEKRATQTILLLVSFFVV---MYWMDFIISFTSDMLWR----------YDPV- ----------------ILT------------------VQKFMMY---------------- ---A--YP-----------------------T-V--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKKL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >7/8.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFK-------TVLYF------------- ---QTGLGVL------------ANTVLLFFYIFIILG----H-----RPKPTDL-ISCQL -------AFVHIMMVLIGGDILLA------------DIFESLNIGNDFKCKTTFFLFRV- ---MRGLSICITCLLSVF-------QAVIISPNTS-LLA-KFKQKVK------KYMAHV- FLCI--------WFFNLSFSTNRIFYVGGFTNVSETTQ-MQVTKSCSLL-PMNYIIRGLI FTISTSRDVFLI-----------GVML-TTSAYMVIFLFRHQRQ----CKHLHGISQ--- ---LRASPEKRATQTILLLVSFFVV---MYWMDFIISFTSDMLW---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >7/8.3-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MRGLSISITCLLSVF-------QAVTISSSTS-LLA-KFKQTVK------KYMTHV- FLCI--------WFFNLSFSTNRIFYVGGFTNVSETTQ-MQVTKSCSLL-PMNYIIRGLI FTISTSRDVFLV-----------GVML-TTSVYMVIFLFRHQRQ----CKHLHGINH--- ---LRESPEKRATQTILLLVSFFVV---MYWMDFIISFTSDMLWR----------YDPV- ----------------ILT------------------VQKFMMY---------------- ---A--YP-----------------------T-V--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKKL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >29-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------LFK-------NVLYF------------- ---QAGFGLL------------ANMFLLFFYTFIILG----H-----RPKPTDL-ISCQL -------TFVHIMMFLTGGDIWLT------------DIFETLNIENDFKCKTIFYISRV- ---MRGLSICTTCLLSVV-------QAVTISPSTS-LLA-KFKQRLK------MYLIYA- FFCI--------WSFNLLYSSNQILYVGGFTNLSETNQ-MKVTKSCTLL-PKNYIIKGLI LTVSISRDVFLV-----------GVML-ITSTYMVIILCRHQRQ----CKHLHSIKH--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFVISTISVLLW---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >29.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------LFK-------NVLYF------------- ---QAGLGVL------------VNMFLLFFYIFIILG----H-----RPKPTDL-ISCQL -------TFVHIMMFLAGGDIWLT------------DIFETLNIENDFKCKTIFYISRV- ---MRGLSICNTCLLSVV-------QAVTISPSTS-LLA-KFKPRLK------MYLIYA- SFCI--------WSFNLLYSSNQILYVGGFTNLSETNQ-MKVTKSCTLL-PKNYIIKGLI LTVSISRDIFLV-----------GVML-TTSTYMLNILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------VLT------------------VQKFVMC---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DSR------I ----I-IMLENMQ--------------------------SK------------------- -------------------HRQN---------FF-------------------------- ------------------------------------------------------------ ------------- >29-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------LFK-------NVLYF------------- ---QAGLGVL------------ANMFLLFFYIFIILG----H-----RPKPTDL-ISCQL -------TFVHIMMFLAGGDIWLT------------DIFETLNIENDFKCKTIFYISRV- ---MRGLSICNTCLLSVV-------QAVTISPSTS-LLA-KFKPRLK------MYLIYA- FFCI--------WSFNLLYSSNQILYVGGFTNLSETNQ-MKVTKSCTLL-PKNYIIKGLI LTVSISRDVFLV-----------GVML-TTSTYMLNILFRHQRQ----CKHLHSISY--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSTSVMLWM----------YDPV- ----------------VLT------------------VQKFVMC---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DNR------I ----I-IMLENMQ--------------------------SK------------------- -------------------HRQN---------FF-------------------------- ------------------------------------------------------------ ------------- >29-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------LFK-------NVLYF------------- ---QAGLGVL------------ANMFLLFFYTFIILG----H-----RPKPTDL-ISCQL -------TFVHIMMFLAGGDIWLT------------DIFETLNIENDFKCKTIFYISRV- ---MRGLSICNTCLLSVV-------QAVTISPSTS-LLA-KFKPRLK------MYLIYA- FFCI--------WSFNLLYSSNQILYVGGFTNLSETNQ-MKVTKSCTLL-PKNYIIKGLI LTVSISRDVFLV-----------GVML-TTSIYMLNILFRHQRQ----CKHLHSISY--- ---LRASPEKRATQTILLLVIFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------VLT------------------VQKFVMC---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DNR------I ----I-IMLENMQ--------------------------SK------------------- -------------------HRQN---------FF-------------------------- ------------------------------------------------------------ ------------- >29-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MMFLAGGDIWLT------------DIFETLNIENDFKCKTIFYISRV- ---MRGLSICTTCLLSVV-------QAVTISPSTS-LLA-KFKQRLK------MYLIYA- FFCI--------WSFNLLYSSNQILYVGGFTNLSETNQ-MKVTKSCTLL-PKNYIIKGLI LTVSISRDVFLV-----------GVML-TTSIYMLNILFRHQRQ----CKHLHSISY--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------VLT------------------VQKFVMC---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DNR------I ----I-IMLENMQ--------------------------SK------------------- -------------------HRQN---------FFKY-VFSFL------------------ ------------------------------------------------------------ ------------- >29.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------MLG----H-----RPKPTDL-ISCQL -------TFVHIMMFLAGGDIWLT------------DIFETLNIENDFKCKTIFYISRV- ---MRGLSICNTCLLSVV-------QAVTISPSTS-LLA-KFKPRLK------MYLIYA- SFCI--------WSFNLLYSSNQILYVGGFTNLSETNQ-MKVTKSCTLL-PKNYIIKGLI LTVSISRDIFLV-----------GVML-TTSTYMLNILFRHQRQ----CKHLHSINH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------VLT------------------VQKFVMC---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DSR------I ----I-IMLENMQ--------------------------SK------------------- -------------------HRQN---------FFLNTFFLFFKD------------ILIY F----------------------------------------------------------- ----YLYV----- >16.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------LFN-------NVLYF------------- ---QAGFGLL------------ANMFLLFFYTFIILG----H-----RPKPTDL-ISCQL -------TFVHIIMFLTGGDIWLT------------DIFETLNIENDFKCKTIFYISRV- ---MRGLSICTTCLLSVV-------QAVTISPSTS-LLA-KFKQRLK------MYLIYA- FFCI--------WSFNLSFSSRLIFYVAGFTNVSENHQ-MKVTKSCSLF-PMNYIIRGLI LTVTMSRDVFLV-----------GVML-TTSAYMLNILFRHQRQ----CKHLHSIRH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSTSVLLWR----------YDPV- ----------------VLT------------------VQKFVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------ENR------I ----I-TMLKNRQ--------------------------SK------------------- -------------------HLQN---------VF-------------------------- ------------------------------------------------------------ ------------- >16.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------LFN-------NVLYF------------- ---QAGFGLL------------ANMFLLFFYTFIILG----H-----RPKPTDL-ISCQL -------TFVHIIMFLTGGDIWLT------------DIFETLNIENDFKCKTIFYISRV- ---MRGLSICTTCLLSVV-------QAVTISPSTS-LLA-KFKQRLK------MYLIYA- FFCI--------WSFNLSFSSRLIFYVAGFTNVSENHQ-MKVTKSCSLF-PMNYIIRGLI LTVTMSRDVFLV-----------GVML-TTSAYMLNILFRHQRQ----CKHLHSIRH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSTSVLLWR--------------- ----------------LFT------------------VLGMVSI---------------- ---S--W-------------------------------------------------I--- --------S-------------------------------CFK-------PNR------F ----D-LLLH-------------------------------------------------- ---------------------EH---------FL-------------------------- ------------------------------------------------------------ ------------- >5/6/244-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMFLLSFYIFIILG----Q-----RPKPTDM-ISCQL -------TFVHIMMFLTAGDIWLT------------DIFALLNIENDFKCKATFYLSRV- ---MRGLSICTTCLLSVV-------QAVSISSSYS-LLS-KFKQKLK------KYMTYA- FLSI--------WSFNISFCSNQIFYVGAYINVSETSQ-MKVSEICSLL-PMNYMIRGVI LIVTTSRDVFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISQ--- ---LRASPEKRATQIILLLVIFFVV---MYWVDFIISTTSFMLWK----------YDPV- ----------------ILT------------------LQKFLMN---------------- ---A--YP-----------------------T-V--T---P--------------LV--- --------Q-------------------------------ISI-------DNR------I ----I-IMLKKLA--------------------------VKT------------------ -------------------PPYI---------FLKK-CFLCSF----------------- ------------------------------------------------------------ ------------- >4-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMFLLCFYIYIILG----H-----RPKPTDL-ISCQL -------TFVHIIMFLTAGDIWLT------------DLLASLNIENDVKCKTTFYINRA- ---MRGLSICITCLLSVF-------QAVTISPSTS-LLA-NFKRKVK------KYMISA- LFYI--------WVFNFSVSTDIIFSVGGFTNVSENKQ-MKVSKSCSLF-PMSYIIRVFI LTVTMSRDVCLV-----------GVML-TTSTYMVIILFWHQRQ----CKHLQSISH--- ---QRASPEKRATQTILLLVIFFVV---MYWVDFTISSTSILLWM----------YDPV- ----------------ALT------------------VQKFVVN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------YNR------I ----I-NRLKNLQ--------------------------SK------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >4-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MISA- LFCI--------WLFNFSVSTDIIFYVGGFTNVSENKQ-IMVTKSCSLL-PLNYIIRGLI LTMTILRDVFLV-----------GVML-TTSVYMVIFLFRHQRQ----CKHLHSISH--- ---LRASPEKRATQTIVLLVVFFVV---MYWVDFTISSTSILLWM----------YDPV- ----------------LLT------------------AQKFVVN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-NRLKNLQ--------------------------SQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >4-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLK-------NVLYF------------- ---QAGLGVL------------ANMFLLCFYIYIILG----H-----RPKPTDL-TSCQL -------TFVHIMMLLTGGDILLT------------DLLASLNTENDFKCKATFYINRM- ---MRGLSISATCLLSVF-------QAVTISPNTS-LLA-NFKQKVK------KYMISA- LFCI--------WFFNFSVSTDIIFYVGGFTNVSENKQ-IMVTKSCSLL-PLNYIIRGLI LTMTILRDVFLV-----------GVML-TTSVYMVIFLFRHQRQ----CKHLHSISH--- ---LRASPEKRATQTIVLLVVFFVV---MYWVDFIISSTSVLLWM----------YDPV- ----------------LLT------------------AQKFVVN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-NRLKNLQ--------------------------SQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >19.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFE-------NVLYI------------- ---QAGLGLL------------PNMFLLFFYNFIILG----N-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNMLA------------IILESLKFGNGIKCKTTFYINRV- ---MRGLSICITCLLSVS-------QAITISPSTS-LLA-KFKSKVK------KHIIYA- FFYL--------WSFNLSFSSRWIFYVAGFTNVSENHQ-MKVTKSCSLF-PMNYIIRGLV LTVTMSRDICLV-----------GVML-ITSTYMVIILFRHQRQ----CKHLHSIRH--- ---LRASPEKRATQTILLLVVFFVV---MNWVDFIISSTSVLLWR----------YDPV- ----------------VLT------------------VQKFVMC---------------- ---A--FP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------ENR------I ----I-IMLKSRQ--------------------------SK------------------- -------------------HCQN--------VF--------------------------- ------------------------------------------------------------ ------------- >19.3-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFE-------NVLYI------------- ---QAGLGLL------------PNMFLLFFYNFIILG----N-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNMLA------------IILESLKFGNGIKCKTTFYINRV- ---MRGLSICITCLLSVS-------QAITISPSTS-LLA-KFKSKVK------KHIIYA- FFYL--------WSFNLSFSSRWIFYVAGFTNVSENYQ-MKVTKSCSLF-PMNYIIRGFI LTVTMSRDVFLV-----------GVML-STSTYMLIILFRHQRQ----CKHLHSKSQ--- ---LRASPE--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >19.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFE-------NVLYI------------- ---QAGLGLL------------PNMFLLFFYNFIILG----N-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNMLA------------IILESLKFGNGIKCKTTFYINRV- ---MRGLSICITCLLSVS-------QAITISPSTS-LLA-KFKSKVK------KHIIYA- FFYL--------WSFNLSFSSRWIFYVAGFTNVSENHQ-MKVTKSCSLF-PMNYIIRGLV LTVTMSRDICLV-----------GVML-ITSTYMVIILFRHQRQ----CKHLHSIRH--- ---LRASPEKRATQTILLLVVFFVV---MYWLDFIISFTSTLLWM----------YDPV- ----------------VLT------------------VQKFVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-HILKKFTP-S----------------------ASR------------------- -------------------FSKK------------------------------------- ------------------------------------------------------------ ------------- >19.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILKSLKFGNVIKCKTTFYINRV- ---MRGLSICITCLLSVS-------QAITISPSTS-LLA-KFKSKVK------KHIIYA- FFYL--------WSFNLSFSIRWIFFVAGFTNVSENHQ-MKVTKSCSLF-PMNYIIRGLF LTVTMSRDICLV-----------GVML-ITSTYMVIILCRHQRQ----CKHLHSISY--- ---LRASPEKRATQTILLLVVFFVV---MYWLDFIISFTSTLFWM----------YDPV- ----------------ILT------------------VQQFVMY---------------- ---A--YP-----------------------T-I--A---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-HILKKFTP-S----------------------ASR------------------- -------------------FSKK------------------------------------- ------------------------------------------------------------ ------------- >19-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MRGLSICITCLLSVS-------QAITISPSTS-LLA-KFKSKVK------KHIIYA- FFYL--------WSFNLSFSSRWIFFVAGFTNVSENHQ-MKVTKSCSLF-PMNYIISGLF LTVTMSRDICLV-----------GVML-ITSTYMVIILCRHQRQ----CKHLHSISY--- ---LRASREKRATQTILLLVVFFVV---MYWFDFIISFTSTLFWM----------YDPV- ----------------ILT------------------VQQFVMY---------------- ---A--YP-----------------------T-I--A---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-HILKKFTP-S----------------------ASR------------------- -------------------FSKK------------------------------------- ------------------------------------------------------------ ------------- >19-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NIFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILS----D-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKFGKDIKCKTTFYINRV- ---MRGLSICITCLLSVS-------QAITISPSTS-LLA-KFKSKVK------KHIIYA- FFYL--------WSFNLSFSSRWIFFVAGFTNVSENHQ-MKVTKSCSLF-PMNYIIRGLF LTVTMSRDICLV-----------GVML-ITSTYMVIILCRHQRQ----CKHLHSISY--- ---LRASPEKRATQTILLLVVFFVV---MYWLDFIISFTSTLFWM----------YDPV- ----------------ILT------------------VQQFVMY---------------- ---A--YP-----------------------T-I--A---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-HILKKFTP-S----------------------ASR------------------- -------------------FSKK-----GLFLFL-------------------------- ------------------------------------------------------------ ------------- >19-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SFE-------NVLYI------------- ---QAGLGLL------------PNMFLLFFYTFIILG----H-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKFGNGIKCKTTFYINRV- ---MRGLSICITCLLSVS-------QAITISPSTS-LLA-KFKSKVK------KHIIYA- FFYL--------WSFNLSFSSRWIFYVAGFTNVSENRQ-MKVTKSCSLF-PMNYIIRGLF LTVTMSRDICLV-----------GVML-ITSTYMVIILCRHQRQ----CKHLHSISY--- ---LRASPEKRATQNILLLVVFFVV---MYWVDFIISFTSTLFWM----------YDPV- ----------------ILT------------------VQQFVMY---------------- ---A--YP-----------------------T-I--A---P--------------LV--- --------Q-------------------------------ISS-------DKR------I IHILI-HILKKFTP-S----------------------ASR------------------- -------------------FSKK------------------------------------- ------------------------------------------------------------ ------------- >19-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NVLYI------------- ---QVGLGLL------------PNMFLLFFYNFIILG----D-----RPKPMDL-ISCQL -------TFVHIMMILSEGDNLLA------------NILESLKFGNDIKCKITFYINRV- ---MRGLSICITCLLSIS-------QAVTISPSTS-SMA-KFKNKVK------KHIIYA- FFYL--------WSFNLSFSSRWIFYVAGFTNVSENYQ-MKVTKSCSLF-PMNYIFRGFI LTVIISRDVFLV-----------GVML-TTSTYMVIILCRHQRQ----CKHLHSISH--- ---LRASPEKRATQTILLLVVFFVV---MYWLDFIISFTSILFWR----------YDPV- ----------------ILT------------------VQKFVMY---------------- ---T--YP-----------------------T-I--A---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-HILKFFTP-N----------------------TSR------------------- -------------------FSKK------------------------------------- ------------------------------------------------------------ ------------- >28-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NVFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILG----D-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKFGNDVKCKTTFYINRV- ---MRGLSVCITCLLSVF-------QAVTISPSTS-LLA-KFKNKVK------THIIYA- FFYF--------WSFNLSFSSRLIVYVAGFTNVSETYQ-MKVTKSCSLY-PMNYIIRGSI LTVIIARDVFLV-----------GVML-TTSTYMVITLCRHQMQ----CKHLHNINC--- ---LRASPEKRATQTILLLVVFFVV---MYWLDFIISFTSTLSWK----------YVPV- ----------------VLT------------------VQKLVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DKR------I ----I-SILKNMH--------------------------SK------------------- -------------------FY--------------------------------------- ------------------------------------------------------------ ------------- >28-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NVFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILG----D-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKFGNDVKCKTTFYINRV- ---MRGLSICITCLLSVF-------QAVTISPSTS-LLA-KFKNKVK------THIIYA- FFYF--------WSFNLSFSSRLIFYVAGFTNVSETYQ-MKVTKSCSLY-PMNYIIRGSI LTVIIARDVFLV-----------GVML-TTSTYMVITLCRHQMQ----CKHLHNISY--- ---LRTSPEKRATQTILLLVVFFVV---MYWLDFIISFTSTLSWK----------YVPV- ----------------VLT------------------VQKLVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DKR------I ----I-SILKSMH--------------------------SK------------------- -------------------FH--------------------------------------- ------------------------------------------------------------ ------------- >28-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NVFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILG----D-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKFGNDVKCKTTFYINRV- ---MRGLSICITCLLSVF-------QAVTISPSTS-LLA-KFKNKVK------THIISA- FFYF--------WSFNLSFSSRLIFYVAGFTNVSETYQ-MKVTKSCSLY-PMNYIIRGSI LTVIIARDVFLV-----------GVML-TTSTYMVITLCRHQMQ----CKHLHNISY--- ---LRASPEKRATQTILLLVVFFVV---MYWLDFIISFTSTLSWK----------YVPV- ----------------VLT------------------VQKLVMY---------------- ---A--YP-----------------------T-L--T---P--------------LV--- --------Q-------------------------------ITS-------DKR------I ----I-SILKNMH--------------------------SK------------------- -------------------FHQI---------F--------------------------- ------------------------------------------------------------ ------------- >28-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NIFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILS----D-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKFGNDVKCKTTFYINRV- ---MRGLSICITCLLSVF-------QAVTISPSTS-LLA-KFKNKVK------THIIYA- FFYF--------WSFNLSFSSRLIFYVAGFTNVSETYQ-MKVTKSCSLY-PMNYIIRGSI LTVIIARDVFLV-----------GVML-TTSTYMVITLCRHQMQ----CKHLHNISY--- ---LRASPEKRATQTILLLVVFFVV---MYWLDFIISFTSTLSWM----------YVPV- ----------------VLT------------------VQKLVMY---------------- ---A--YP-----------------------T-L--T---P--------------LV--- --------Q-------------------------------ITS-------DKR------I ----I-SILKNMH--------------------------SK------------------- -------------------FHWI---------F--------------------------- ------------------------------------------------------------ ------------- >28-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NIFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILS----D-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKFGKDIKCKTTFYINRV- ---MRGLSICITCLLSVF-------QAVTISPSTS-LLA-KFKNKVK------THIIYA- FFYF--------WSFNLSFSSRLIFYVAGFTNVSETYQ-MKVTKSCSLY-PMNYIIRGSI LTVIIARDVFLV-----------GVML-TTSTYMVITLCRHQMQ----CKHLHNISY--- ---LRASPEKRATQTILLLVVFFVV---MYWLDFIISFASTLSWM----------YVPV- ----------------VLT------------------VQKLVMY---------------- ---A--YP-----------------------T-L--T---P--------------LV--- --------Q-------------------------------ITS-------DKR------I ----I-SILKNMH--------------------------SK------------------- -------------------FH--------------------------------------- ------------------------------------------------------------ ------------- >18-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NVFYI------------- ---QAGLGVL------------ANMFLLFFYTSKILG----D-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKFGNDVKCKTTFYINRV- ---MRGLSVCITCLLSVF-------QAVTISPSTS-LLA-KFKNKVK------THIIYA- FFYF--------WSFNLSFSSRLIVYVAGFTNVSETYQ-MKVTKSCSLF-PMNYIIRGLV LTVAVSRDVFLV-----------GLML-TTSTYMVIILCRHQRQ----CKHLHSNSH--- ---LRASPEKRATQTILLLVVFFVV---MYWLDFIISFTSSLSWM----------YVPV- ----------------VLT------------------VQKLVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DKR------I ----I-STLKNVH--------------------------SK------------------- -------------------FH--------------------------------------- ------------------------------------------------------------ ------------- >18.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NVFYI------------- ---QAGLGIL------------ANMFLLFFYTSIILG----D-----RPKPMDL-ISSQL -------TFIHIMMILSEGDNLLA------------NILESLKLGNDIKCKTTFYINRV- ---MRGLSVCITCLLSVF-------QAVTISPSTS-FLA-QFKNKVK------THIIYA- FFYF--------WSFNLSFSSRLIFYVAGFTNVSGTHQ-MKVTKSCSLF-PMNYIIRGLI LTVAISRDVFLV-----------GLML-TTSTYMVIILCRHQKQ----CKHLHSNSH--- ---IRASPEERATQTILLLVVFFVV---MYWLDFIISFTSTLSWM----------YVPV- ----------------VLT------------------VQKLVMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------ITS-------DKR------I ----I-SILKNVH--------------------------SK------------------- -------------------FH--------------------------------------- ------------------------------------------------------------ ------------- >18-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NVFYI------------- ---QAGLGIL------------ANLFLLFFYTSKILV----D-----RPKPMDL-ISSQL -------TFIHIMMILSEGDNLLA------------NILESLKLGNDIKCKTTFYINRV- ---MRGLSVCITCLLSVF-------QAVTISPSTS-FLA-QFKNKVK------THIIYA- FFYF--------WSFNLSFSSRLIFYVAGFTNVSGTHQ-MKVTKSCSLF-PMNYIIRGLI LTVAISRDVFLV-----------GLML-TTSTYMVIILCRHQRQ----CKHLHSNSH--- ---IRASPEERATQTILLLVVFFVV---MYWLDFIISFTSTLSWM----------YVPV- ----------------VLT------------------VQKLVMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------ITS-------DKR------I ----I-SILKNVH--------------------------SK------------------- -------------------FH--------------------------------------- ------------------------------------------------------------ ------------- >18-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NVFYI------------- ---QAGLGIL------------ANLFLLFFYTSKILV----D-----RPKPMDL-ISSQL -------TFIHIMMILSEGDNLLA------------NILESLKLGKDIKCKTTFYINRV- ---MRGLSVCITCLLSVF-------QAVTISPSTS-FLA-QFKNKVK------THIIYA- FFYF--------WSFNLSFSSRLIFYVAGFTNVSGTHQ-MKVTKSCSLF-PMNYIIRGLI LTVAISRDVFLV-----------GLML-TTSTYMVIILCRHQRQ----CKHLHSNSH--- ---IRASPEERATQTILLLVVFFVV---MYWLDFIISFTSTLSWM----------YVPV- ----------------VLT------------------VQKLVMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------ITS-------DKR------I ----I-SILKNVH--------------------------SK------------------- -------------------FH--------------------------------------- ------------------------------------------------------------ ------------- >18.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ML---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ FFYF--------WSFNLSFSSRLIFYVAGFTNVSGTHQ-MKVTKSCSLF-PMNYIIRGLI LTVAISRDVFLV-----------GLML-TTSTYMVIILCRHQKQ----CKHLHSNSH--- ---IRASPEERATQTILLLVVFFVV---MYWLDFIISFTSTLSWM----------YVPV- ----------------VLT------------------VQKLVMY---------------- ---A--YP-----------------------T-I--S---P--------------LV--- --------Q-------------------------------ITS-------DKR------I ----I-SILKNVH--------------------------SK------------------- -------------------FH--------------------------------------- ------------------------------------------------------------ ------------- >18/19/28-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NIFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILS----D-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKLGNDIKCKTTFYINRV- ---MRGLSVCITCLLSVF-------QAVTISPSTS-FLA-QFKNKVK------THIIYA- FFYF--------WSFNLSFSSRLIFYVAGFTNVSGTHQ-MKVTKSCSLF-PMNYIIRGLI LTVAISRDVFLV-----------GLML-TTSTYMVIILCRHQRQ----CKHLHSISH--- ---LRASPEKRATQAILLLVIFFVV---MYWVDFIISSTSVLLWM----------YDPI- ----------------ILQ------------------VQKFVMY---------------- ---A--FP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-IMLKNMH--------------------------SK------------------- -------------------HHQS---------FF-------------------------- ------------------------------------------------------------ ------------- >243-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NVFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILG----E-----RPKPMDL-ISCQL -------TFVHIMMILSEGDNLLA------------NILESLKLGNNIKCKTTFYINRV- ---MRGLSICVTCLLSVF-------QAITISPSTS-FLG-KFKNKVK------TRIIYA- FFYF--------WSFNLSFSSRLIFYVAGFINVSETHQ-MKVTKSCSLF-RMNYIIRELI LTVIISRDVFLV-----------GVML-TTSTYMVVILFRHQRQ----CKHLHGINH--- ---LRASPEKRATQTILLLLVFYVV---MYWVDLIISMTSTLSWM----------YDPD- ----------------VLT------------------VQKFVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------V ----I-SILKNLH--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >243.2-s ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------M-- --------YSSLMS------------------SLE-------NILYI------------- ---QAGLGVL------------ANMFLLFFYTSIILG----D-----RPKPMDL-ISCQL -------TLIHIMMILSEGDNLLA------------NILESLKLGNDIKCKTTFYINRV- ---MRGLSICITCLLSVF-------QAITISPSTS-LLA-KFKNKVK------THIMYA- FFYF--------WSFNLSFSSRLIVYVAGYINVSETYQ-MKVTKSCSLF-RMNYIIRELI LTVVISRDVFLV-----------GVML-TTSTYMVITLFKHERQ----CKHLHSIRN--- ---LRASPEKRATQTILLLVVFFVV---MYWLDLIISITSTLSWM----------YDPD- ----------------VLT------------------VQKFVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------V ----I-SILNNFH--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >243.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ML---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ FFYF--------WSFNLSFSSRLIVYVAGYINVSETYQ-MKVTKSCSLF-RMNYIIRELI LTVVISRDVFLV-----------GVML-TTSTYMVITLFKHERQ----CKHLHSIRN--- ---LRASPEKRATQTILLLVVFFVV---MYWLDLIISITSTLSWM----------YDPD- ----------------VLT------------------VQKFVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------V ----I-SILNNFH--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >243-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NVFYI------------- ---QAGLGIL------------ANLFLLFFYTSKILV----D-----RPKPMDL-ISSQL -------TFIHIMMILSEGDNLLA------------NILESLKLGKDIKCKTTFYINRV- ---MRGLSICITCLLSVF-------QAITISPSTS-LLA-KFKNKVK------THIMYA- FFYF--------WSFNLSFSSRLIVYVTGYINVSETYQ-MKVTKSCSLF-RMNYIIRELI LTVMISRDVFLV-----------GVML-TTSTYMVITLCKHERQ----CKHLHSIRN--- ---LRASPEKRATQTILLLVVFFVV---MYWLDLIISITSTLSWM----------YDPD- ----------------VLT------------------VQKFVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------V ----I-SILNNFH--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >243-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLE-------NIFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILS----D-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKFGKDIKCKTTFYINRV- ---MRGLSICITCLLSVF-------QAITISPSTS-LLA-KFKNKVK------THIMYA- FFYF--------WSFNLSFSSRLIVYVTGYINVSETYQ-MKVTKSCSLF-RMNYIIRELI LTVMISRDVFLV-----------GVML-TTSTYMVITLCKHERQ----CKHLHSIHN--- ---LRASPEKRATQTILLLVVFFVV---MYWLDLIISITSTLSWM----------YDPN- ----------------VLT------------------VQKFVMY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------V ----I-SILNNFH--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >basal18-p ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MN-- --------ILYTMS------------------SLE-------NVFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILG----E-----RPKPMDL-ISCQL -------TFVHIMMILSEGDNLLA------------NILESLKLGNDIKCKTTFYINRV- ---MRGLSVCITCLLSVF-------QAVTISPSTS-LLA-QFKNKVK------RHIIYA- FFYF--------WSFNLSFSSRLIFYVAGFTNVSETHQ-MKVSKSCLLF-PMNHIIRGLM LTVVMSRDVFLV-----------GIMM-TTSAYMVIILFRHQRQ----CKHLHGISH--- ---QRASPEKRATQTILLLVIFF------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >21-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SSN-------TVLYF------------- ---QAGFGVL------------VNMFLLFFYTFIILC----H-----RPKPMDL-ISCQL -------TFIHIMMILTGGD-----------------ILESLKFGNDVKCKTVFYINRV- ---MRGLSICITCLLSVF-------QAITISPSTS-LFA-KFKQKLK------TYMMYA- FFYL--------WSFNVLFSSRWFFYVAGFTNMSETHQ-MKVSQSCFLY-PVNHIIRGLM LTVAMSRDVFLV-----------GVMM-TTSTYMVIILFRHQRQ----CKHLHSIRH--- ---LRASPEKRATQMILILVVFFVV---MYWVDFIISFTSILLWV----------YDPV- ----------------VLT------------------VQMFVMN---------------- ---I--YP-----------------------I-I--T---P--------------VV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNFR--------------------------SE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >21-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SSN-------TVLYF------------- ---QAGFGVL------------VNMFLLFFYTFIILC----H-----RPKPMDL-FSCQL -------TFIHIMMILTGGDTLLA------------DILESLKFGNDVKCKTIFYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LFA-KFKQKLK------KYMMYA- FFYL--------WSFNVLFSSRWFFYVAGFTNMSETHQ-MKVSKSCFLY-PVNHIIRGLM LTVAMSRDVFLV-----------GVMM-TTSTYMVIILFRHQRQ----CKHLHSISN--- ---LRGSPEKRATQIILLLVVFFVV---MYWVDFIISFTSILLWV----------YDPV- ----------------VLT------------------VQMFVMN---------------- ---I--YP-----------------------T-I--T---P--------------VV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNLR--------------------------SE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >21-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SSN-------TVLYF------------- ---QAGFGVL------------VNMFLLFFYTFIILC----H-----RPKPMDL-FSCQL -------TFIHIMMILTGGDTLLA------------DILESLKFGNDVKCKTVFYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTS-LFA-KFKQKLK------KYMMYA- FFYL--------WSFNVLFSSRWFFYVAGFTNMSETHQ-MKVSKSCFLY-PVNHIIRGLM LTVAMSRDIFLV-----------GVMM-TTSIYMVIILFRHQRQ----CKHLHSISN--- ---LRGSPEKRATQIILLLVVFFVV---MYWVDFIISFTSILLWV----------YDPV- ----------------VLT------------------VQMFVMN---------------- ---I--YP-----------------------T-I--T---P--------------VV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNLR--------------------------SE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >21-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SSN-------TVLYF------------- ---QAGFGVL------------VNMFLLFFYTFIILC----H-----RPKPMDL-FSCQL -------TFIHIMMILTGGDTLLA------------DILESLKFGNDIKCKTVFYINRV- ---MRGLSICITCLLSVF-------QAVTISPNTF-LFA-KFKQKLK------KYMMYA- FFYL--------WSFNVLFSSRWFFYVAGFTNMSETHQ-MKVSKSCFLY-PVNHIIRGLM LTVAMSRDVFLV-----------GVMM-TTSTYMVIILFRHQRQ----CKHLHSISN--- ---LRGSPEKRATQIILLLVVFFVV---MYWVDFIISFTSILLWA----------YDPV- ----------------VLT------------------VQMFVMN---------------- ---I--YP-----------------------T-I--T---P--------------VV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNLR--------------------------SE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >21.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SSN-------TVRYF------------- ---QAGFGVL------------VNMFLLFFYTFIILG----H-----RPKPMDL-ISCQL -------TFIHIMMILTGGDILFA------------DILESLKFGNDVKCKTTFYINRV- ---MRGLSICITCLLSVF-------QAVTISPSTS-LLA-KFKHKVK------THIIYA- FSLL--------WSFNLSFSSRLIFYVAGFTNVSETHQ-MKVSKSCLLF-PMNHIIRGLM LTVVMSRDVFLV-----------GIMM-TTSAYMVIILFRHQRQ----CKHLHGISH--- ---QRASPEKRATQTILLLVIFFVV---MYWVDFIISFTSILLWV----------YDPV- ----------------VLT------------------VQMFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNLK--------------------------SK------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >21.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MI------------------TLG-------TLIFTA------------ W-EEISL---------------KQKFQKQNHSMVIFG----H-----RPKPMDL-ISCQL -------TFIHIMMILTGGDILFA------------DILESLKFGNDVKCKTTFYINRV- ---MRGLSICITCLLSVF-------QAVTISPSTS-LLA-KFKHKVK------THIIYA- FSLL--------WSFNLSFSSRLIFYVAGFTNVSETHQ-MKVSKSCLLF-PMNHIIRGLM LTVVMSRDVFLV-----------GIMM-TTSAYMVIILFRHQRQ----CKHLHGISH--- ---QRASPEKRATQTILLLVIFFVV---MYWVDFIISFTSILLWV----------YDPV- ----------------VLT------------------VQMFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNLK--------------------------SK------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >22/23-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QSGLGVL------------ANMFLLTFYIFIILC----H-----RPKPMDL-ISCQL -------SFVHIMMFLTAGDIWLS------------DLFESLNIEKDFVCKATFYTSRV- ---MRGLSMCITCLLSVF-------QAVTISPSTS-LLA-KFKHKLK------KYIICA- FFYF--------WSFNLSFSSSLFFSVGAYNNMSDTNQ-MKVTKYCSHF-PMNNFIKELN VIVSTLRDVFLV-----------EVML-TTSVYMVIILYRHQRQ----CKHLHSIRH--- ---LRASPEKRATQTILLLVVFFVV---MYWVDFIISSTSVLLWR----------YDPV- ----------------VLT------------------VQKFVVN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I ----I-NVLKNLW--------------------------LK------------------- -------------------S---------------------------------------- ------------------------------------------------------------ ------------- >22.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------ML-TTSIYMVIILYRHQRK----CKHLHSIRH--- ---LRTSPEKKATQTILLLLVFFVV---MYWVDLIISSTSVLLWR----------YDPI- ----------------ILT------------------VQKFVVN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNLW--------------------------LK------------------- -------------------CHQT---------V--------------------------- ------------------------------------------------------------ ------------- >22.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QSGLGVL------------ANMFLLFFYIFIILG----H-----RPKPMDL-ILCQF -------SFVHILMFLTAGDIWLS------------DLFESLNIENDFICKATFYTGRV- ---MRGLSMCITCLLGVF-------QAVTISPSTS-LLA-KFKHKLK------KYIIYA- VFYI--------WFLNFSINSHMIVYVGGFNNRSETNQ-MRITKTCSHF-PMNNIIKELI LTVITLKDVFLV-----------GVML-TTSIYMVIILYRHQRK----CKHLHSIRH--- ---LRTSPEKKATQTILLLLVFFVV---MYWVDLIISSTSVLLWR----------YDPI- ----------------ILT------------------VQKFVVN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNLW--------------------------LK------------------- -------------------CHQT---------V--------------------------- ------------------------------------------------------------ ------------- >22-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-ILCQF -------SFVHIIMFLTGGDIWLT------------DLFESLNIENDFKCKATFYTGRV- ---MRGLSMCITCLLGVF-------QAVTISPSTS-LLA-KFKHKLK------KYIIYA- VFYI--------WFLNFSINSHMIIYVGGFNNVSETNQ-MRITKTCSHF-PMNYIIRELI LTVTTLRDVFLV-----------GVML-TTSIYMVIILYRHQRQ----CKHLHSIRH--- ---LRASPEKKATQTILLLLVFFVV---MYWVDLIISSTSVLLWR----------YDPV- ----------------ILT------------------VQKFVVN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNLW--------------------------LK------------------- -------------------CHQT---------V--------------------------- ------------------------------------------------------------ ------------- >23-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLFI------------- ---QSGLGVL------------ANMFLLIFYILIILG----H-----RPKPMDL-ISCQL -------SFVHIMMLLTAGDNWFT------------DLFESLNIKNDFICKAAFYTSRV- ---MRGLSMGITCLLSVF-------QAVTISPSTS-LLT-KFKHKLK------NYIIYA- VFYI--------CFFNFSINSHMIVYVGGFNNVSKTNQ-MRITKTCSHF-PMNNIIKELI LTVITLKDVFLV-----------GVML-TTSIYMVIILYRHQRK----CKHLHSIRH--- ---LRASPEKKATQTILLLVVFFVV---MYWVDLIISSTSVLLWM----------YDPV- ----------------ILT------------------VQKFVVN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNLW--------------------------LK------------------- -------------------CHQT---------V--------------------------- ------------------------------------------------------------ ------------- >24.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NILYF------------- ---QAGLGVL------------ANMFLLTFYIFTIPG----H-----KPKPVDL-ISCQL -------TFIHIIMVLTGWDIWLT------------DMFELLNIENDFKCKATFYINRV- ---MRGLSISITCLLSVF-------QAVTISPSDS-LLA-KFKHKLK------KYIIYA- FFYV--------WSFNLSFSSNQFFSVGAYANLSETSQ-MKVTNYCSHF-PINIVIRGLI LTVTTLRDVFLV-----------GVML-TTSAYMIVFLFRHQRL----CQHLHSIRH--- ---LRASPEKKATQIILLLVVFFVV---MYWVDFFISSTSVLLWR----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DDR------I ----I-NVLENLW--------------------------P-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >24-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NILYF------------- ---QAGLGVL------------ANMFLLTFYIFTIPC----H-----SPKPVDL-ISCQL -------TFIHIIMVLTGWDIWLT------------DMFELLNIENDFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTISPSTS-LLA-KFKHKLK------KYIIYA- FFYV--------WSFNLSFSSNQFFSVGAYANLSETSQ-MKVTNYCSHF-PMNNVIRGLI LTVTTLRDVCLV-----------GVML-TTSSYMVVFLCRHQRQ----CQHLHSIRH--- ---LRASPEKKATQIILLLVVFFVV---MYWVDFFISSTSILLWR----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ITS-------DDR------I ----I-NVLKNLW--------------------------P-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >24-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NILYF------------- ---QAGLGVL------------ANMFLLTFYIFTIPC----H-----SPKPVDL-ISCQL -------TFIHIIMVLTGWDIWLT------------DMFELLNIENDFKCKATFYINRV- ---MRGLSICITCPLSVF-------QAVTISPSTS-LLA-KFKHKLK------KYIIYA- FFYV--------WSFNLSFSSNQFFSVGAYANLSETSQ-MKVTNYCSHF-PMNNIIRGLI LTVTTLRDVFLV-----------GVML-TTSSYMVVFLCRHQRQ----CQHLHSIRH--- ---LRASPEKKATQIILLLVVFFVV---MYWVDFFISSTSILLWR----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DER------I ----I-NVLKNLW--------------------------P-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >24-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NILYF------------- ---QAGLGVL------------ANMFLLIFYIFTIPC----H-----SPKPVHL-MSCQL -------TFIHIIMVLTGWDIWLT------------DMFELLNIENDFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTISPSAS-LLA-KFKHKLK------KYIIYA- FFYV--------WSFNLSFSSNQFFSVGAYANLSETSQ-MKVTNYCSHF-PMNNVIRGLI LTVTTLRDVFLV-----------GVML-TTSSYMVVFLCRHQRQ----CQHLHSIRH--- ---LRASPEKKATQIILLLVVFFVV---MYWVDFFISSTSILLWR----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DER------I ----I-NVLKNLW--------------------------P-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >24-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SSN-------TVLYF------------- ---QAGFGVL------------VNMFLLFFYTFIILC----H-----RPKPMDL-FSCQL -------TFIHIMMILTGGDTLLA------------DILESLKFGNDVKCKTVFYINRV- ---MRGLSICITCLLSVF-------QAVTISPSAS-LLA-KFKHKLK------KYIIYA- FFYV--------WSLNLSFSSNQFFSVGAYANLSETSQ-MKVTNYCSHF-PMNNVIRGLI LTVTTLRDVFLV-----------GVML-TTSSYMVVFLCRHQRQ----CQHLHSIRH--- ---LRASPEKKATQIILLLVVFFVV---MYWVDFFISSTSILLWR----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ITS-------DDR------I ----I-NVLKNLW--------------------------P-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >24-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QAGLGVL------------ANMFLLTSYSFTISA----H-----SPKPVDL-ISCQL -------TFIHIIMVLTGWDIWLT------------DMFELLNIENDVKCKATFYINRV- ---MRGLSICTTCLLSVF-------QAVTISPSAS-LLA-KFKHKLK------KFIIYA- FFYV--------WSFNLSFSSNQFFSVGAYTNLSETSQ-MQVTNYCSHF-PINNIIRGLI LTVTTLRDVFLV-----------GVML-STSAYMVIFLFRHQRQ----CQHLHSIRK--- ---LRASPEKKATQIILLQVVFFVV---MYWVDFIISSTSVLLWR----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---I--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I --------FK-------------------------------------------------- -------------------CHQA---------FFKGVISVFFK-------------KEIY F---------------SGLCHHRATLDLNSVDSPT-VSRGLSTP---------------- ----QAH------ >26.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QSGLGVL------------ANMFLLIFYIFIILG----H-----RPKPIDL-ISCQL -------NFVHIIMVLTAGDIWLS------------DLFESLNMENNFKCKAIFYINRV- ---MRGLSICITCLLSVF-------QIVTMSPSTS-FLA-KFKHTLK------KYIIYV- FFYF--------WLFNLSFSSNQLFSASAYTNVSDTNQ-MKISKYCSYF-PTNKIIRGLI LTVTTLRDVFLV-----------GVMV-TTSAYMVLLLFRHQRQ----CKHLHSIKY--- ---WRASPEKKATQTILVLVVFFVV---MYWVDLIISSTSVLLWR----------YDTV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I --------LK-------------------------------------------------- -------------------CHQA---------FFKGAIFVFFK-------------M-IF I---------------PLVCA--------SIIPPW-I----------------------- ------------- >26.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QSGLGVL------------ANMFLMIFNIFIILG----H-----RPKPIDL-ISCQL -------NFVHIMMFLTAGDIWLT------------DLFASLNIENNFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTMSPSTS-FLA-KFKHTLK------KYIIYV- FFYF--------WLFNLSFNSNQLFSAGAYTNVSDTNQ-MKISKYCSYF-PTNKIIRGLI LTVTTLRDVFLV-----------GVMV-TTSAYMVLLLFRHQRQ----CKHLHSINY--- ---WRASPEKKATQTILVLVVFFVV---MYWVDLIISSTSVLLWR----------YDTV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I --------LK-------------------------------------------------- -------------------CHQA---------FFKGAIFVFFK-------------KDIY S---------------SGLCQHHATLDLNSVDSPT-VSGGISTI---------------- ----QVH------ >26-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QSGLGVL------------ANMFLLIFYIFIVLG----H-----RPKPIDL-ISCQL -------NFVHIMMFLTAGDIWLT------------DLFASLNIENNFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTMSPSTS-FLA-KFKHTLK------KYIIYI- FFYF--------WLFNLSFSSNQLFSAGAYTNVSDTNQ-MKISKYCSYF-PTNKIIRGLI LTVTTLRDVFLV-----------GVMV-TTSAYMVLLLFRHQKQ----CKHLHSINY--- ---WRASPEKKATQTILVLVVFFVV---MYWVDLIISSTSVLLWR----------YDTV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I --------LK-------------------------------------------------- -------------------CHQA---------FFKGAIFVFFK-------------KDIY S---------------SGLCQHHATLDLNSVDSPT-VSGGISTI---------------- ----QVH------ >26-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QSGLGVL------------ANMFLLIFYIFIILG----H-----RPKPIDL-ISCQL -------NFVHIMMFLTAGDIWLT------------DLFASLNIENNFKCKATFYINRV- ---MRGLSICNTCLLSVF-------QAVTMSPSTS-FLA-KFKHTLK------KYIIYV- FFYF--------WLFNLSFSSNQLFSAGAYTNVSDTNQ-MKISKYCSYF-PTNKIIRGLI LTVTTLRDVFLV-----------GVMV-TTSAYMVLLLFRHQRQ----CKHLHSINY--- ---WRASPEKKATQTILVLVVFFVV---MYWVDLIISSTSVLLWR----------YDTV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I --------LK-------------------------------------------------- -------------------CHQA---------FFKGAIFVFFK-------------KDIY S---------------SGLCQHHATLDLNSVDSPT-VSGGISTI---------------- ----QVH------ >26.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QSGLGVL------------ANMFLLIFYIFIILG----H-----RPKPIDL-ISCQL -------NFVHIMMFLTAGDIWLT------------DLFASLNIENNFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTMSPSTS-FLA-KFKHTLK------KYIIYV- FFYF--------WLFNLSFSSNQLFSAGAYTNVSDTNQ-MKISKYCSYF-PTNKIIRGLI LTVTTLRDVFLV-----------GVMV-TTSAYMVLLLFRHQRQ----CKHLHSINY--- ---WRASPEKKATQTILVLVVFFVV---MYWVDLIISSTSVLLWR----------YDTV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I --------LK-------------------------------------------------- -------------------CHQA---------FFKGAIFVFFK-------------KDIC S---------------SGLCQHHATLNLNSVDSPT-VSGGISTI---------------- ----QVH------ >26.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NILYF------------- ---QAGLGVL------------ANMFLLTFYIFTIPC----H-----SPKPVDL-ISCQL -------TFIHIIMVLTGWDIWLT------------DMFELLNIENDFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTMSPSTS-FLA-KFKHTLK------KYIIYV- FFYF--------WLFNLSFNSNQLFSAGAYTNVSDTNQ-MKISKYCSYF-PTNKIIRGLI LTVTTLRDVFLV-----------GVMV-TTSAYMVLLLFRHQRQ----CKHLHSINY--- ---WRASPEKKATQTILVLVVFFVV---MYWVDLIISSTSVLLWR----------YDTV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I --------LK-------------------------------------------------- -------------------CHQA---------FFKGAIFVFFK-------------KDIY S---------------SGLCQHHATLDLNSVDSPT-VSGGISTI---------------- ----QVH------ >26.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QSGLGVL------------ANMFLLIFYIFIILG----H-----RPKPIDL-ISCQL -------NFVHIMMFLTAGDIWLT------------DLFASLNIENNFKCKATFYINRV- ---MRGLSICITCLLSVF-------QAVTMSPSTS-FLA-KFKHTLK------KYIIYV- FFYF--------WLFNLSFSSNQLFSAGAYTNVSDTNQ-MKISKYCSYF-PTNKIIRGLI LTVTTLRDVFLV-----------GVMV-TTSAYMVLLLFRHQRQ----CKHLHSINY--- ---WRASPEKKATQTILVLVVFFVV---MYWVDLIISSTSVLLWR----------YDTV- ----------------ILT------------------VQKFVMN---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----S-MMLKNMQ---------------------------K------------------- ------------------LCNQI---------FKKV------------------------ ------------------------------------------------------------ ------------- >26-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QSGLGVL------------ANMFLLIFYIFIILR----H-----RPKPIDL-ISCQL -------NFVHIIMFLTAGDIWLS------------DLFASLNIENDFKCKATFYINRV- ---MRGLSLCITCFLSVF-------QAVTMSPSTS-FLA-KFKRTLK------KYIIYI- FFYF--------WLFNLSFSSNQLFSAGAYTNVSNTNQ-MKIEKYCSHI-PTNNLIRGLI LAVTILRDMFLV-----------GVML-TTSAYMVLFLFRHQRQ----CKHLHSIKY--- ---WRASPEKKATQTILVLVVFFVV---MYWVDLIILSTSVLLWR----------YDPV- ----------------ILT------------------VQKFVMN---------------- ---I--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DNR------I --------FK-------------------------------------------------- -------------------CHQA---------FFKGVISVFFK-------------KEIY F---------------SGLCHHRATLDLNSVDSPT-VSRGLSTP---------------- ----QAH------ >24.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NILYF------------- ---QAGLGVL------------ANMFLLTFYIFTIPG----H-----KPKPVDL-ISCQL -------TFIHIIMVLTGWDIWLT------------DMFELLNIENDFKCKATFYINRV- ---MRGLSISITCLLSVF-------QAVTISPSDS-LLA-KFKHKLK------KYIIYA- FFYV--------WSFNLSFSSNQFFSVGAYANLSETSQ-MKVTNYCSHF-PINIVIRGLI LTVTTLRDVFLV-----------GVML-TTSAYMIVFLFRHQRL----CQHLHSIRH--- ---LRASPEKKATQIILLLVVFFVV---MYWVDFFISSTSVLLWRGHMRSLDSLELDFA- ----------------VLSQ--VDSHLCC-LQF-LPIMNKAAVN---------------- ---IVEYPKERRPRGRKCPPTGVFKKQETKKM-V--T---P--------------LS--- --------E-------------------------------KRP-------KN-------- --------FR-------------------------------------------------- -------------------IGQD---------IQP------------------------- -------------------------------------KRDLT------------------ ------------- >25/30-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLM-------NILYF------------- ---QAGLGVL------------ANTFLLCFYTFTILG----H-----RSKPMDL-TSCQL -------TFAHILFLLTGGDNWLA------------VILESLNIENDFKCKTIFYISRV- ---MRGFSICITCLLSVF-------QAVTISPHTS-LLA-KFKHKLK------TYIIYA- VFYI--------WFFNFLVNSHMIFYVGGFNNVSETNQ-IRVTKSCSLF-LMNYIISGLI FTVTTFRDVFLV-----------GVML-ITNAYIVIILFRHQRH----CKHLHSIRH--- ---LRVSPEKRATQTILLLVVFFVV---MYWVDFIISSTSLLLWM----------YDPV- ----------------ILT------------------VQKLVVT---------------- ---A--YP-----------------------T-I--T---P--------------LI--- --------Q-------------------------------ISS-------DKR------V ----I-NVLKNLQ--------------------------SK------------------- -------------------CQQI---------F--------------------------- ------------------------------------------------------------ ------------- >30-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLK-------NILYF------------- ---QAGLGIL------------ANTFLLCFYTFTILG----H-----RSKPMDP-TSCQL -------TFAHILFLLAGGDNWLA------------VILESLNIENDFKCKAIFYTSRV- ---MRGFSICITCLLSVF-------QAVTISPHTS-LLA-KFKHKLN------TYIFYA- VLYI--------WFFNFLANSHMIFYVGGFNNVSETNQ-MRVTQSCSLF-PMNYVISGLI FTVTTFRDVFLV-----------GVML-ITSAYIVIILFRHQRH----CRHLHSIRH--- ---LRVSPEKRATQTILLLVVFFVV---MYWVDFIISSTSLLLWM----------YDPV- ----------------ILT------------------VQKLVVT---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------V ----I-NVLKNSQ--------------------------SK------------------- -------------------CQQI---------F--------------------------- ------------------------------------------------------------ ------------- >30-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLK-------NILYF------------- ---QAGLGIL------------ANTFLLCFYTFTILG----H-----RSKPMDP-TSCQL -------TFAHILFLLAGGDNWLA------------VILESLNIENDFKCKAIFYTSRV- ---MRGFSICITCLLSVF-------QAVTISPHTS-LLA-KFKHKLN------TYIFYA- VLYI--------WFFNFLANSHMIFYVGGFNNVNETNQ-MRVTQSCSLF-LMNYVISGLI FTVTTFRDVFLV-----------GVML-ITSAYIVIILFRHQRH----CRHLHSIRH--- ---LRVSPEKRATQTILLLVVFFVV---MYWVDFIISSTSLLLWM----------YDPV- ----------------ILT------------------VQKLVVT---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------V ----I-NVLKNSQ--------------------------SK------------------- -------------------CQQI---------F--------------------------- ------------------------------------------------------------ ------------- >25-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLT-------NILCF------------- ---QAGLGIL------------ANTFLLCFYTFTILG----H-----RSKPMDL-TSCQL -------TFAHILFLLAGGDNWLA------------VILESLNIENDFKCKAIFYTSRV- ---MRGFSICITCLLSVF-------QAVTISPHTS-LLA-KFKHKLK------TYIIYA- VFYI--------WFFNFLVCSHMLVYVGGFNNVSETNQ-MRVTESCSLF-LMNYIISGLI FTVTTFRDVFLV-----------GVML-ITNAYIVIILFRHQRH----CKHLHSIRH--- ---LRVSPEKRATQTILLLVVFFVV---MYWVEIIISSTSLLLWM----------YDPV- ----------------ILT------------------VQKLVVT---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------L ----I-NVLKNLQ--------------------------SK------------------- -------------------CQQN---------F--------------------------- ------------------------------------------------------------ ------------- >25-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLT-------NILYF------------- ---QAGLGIL------------ANTFLLCFYTFTILG----H-----RSKPMDP-TSCQL -------TFAHILFLLAGGDNWLA------------VILESLNIENDFKCKAIFYTSRV- ---MRGFSICITCLLSVF-------QAVTISPHTS-LLA-KFKHKLK------TYIIYA- VFYI--------WFFNFLVCSHMLVYVGGFNNVSETNQ-MRVTESCSLF-FMNYIISELI FTVTTFRDVFLV-----------GVML-ITNAYIVIILFRHQRH----CKHLHSIRH--- ---LRVSPEKRATQTILLLVVFFVV---MYWVEIIISSTSLLLWI----------YDPV- ----------------FLT------------------VQKLVVT---------------- ---A--YP-----------------------T-V--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------V ----I-NVLKNLQ--------------------------SK------------------- -------------------CQQI---------F--------------------------- ------------------------------------------------------------ ------------- >25-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLT-------NILYF------------- ---QAGLGIL------------ANTFLLCFYTFTILC----H-----RSKPMDL-TSCQL -------TLAHILFLLAGGDNWLA------------VILESLNIENDFKCKAIFYTNRV- ---MRGFSICITCLLSVF-------QAVTISPHTS-LLA-KFKHKLK------TYIIYA- VFYI--------WFYNFLVCSHLLVYVGGFNNVSETNQ-MRVTESCSLF-LMNYIISGLI FTVTTFRDVFLV-----------GVML-ITNAYIVIILFRHQRH----CKHLHSIRH--- ---LRVSPEKRATQTILLLMVFFVV---MYWVEIIISSTSLLLWM----------YDPG- ----------------FLT------------------VQKLIVT---------------- ---V--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------V ----I-NVLKNLQ--------------------------SK------------------- -------------------CQQI---------F--------------------------- ------------------------------------------------------------ ------------- >25-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLK-------NILYF------------- ---QAGLGIL------------ANTFLLCFYTFTILG----H-----RSKPMDL-TSCQL -------TFAHILFLLTGGDNWLA------------VILESLNIESDFKCKAIFYTSRV- ---MRGFSICITCQLSVF-------QAVTISPHTS-LLA-KFKHKLK------TYIIYA- VFYI--------WFFNFLVCSHLLVYVGGFNNVSETNQ-MRVTESCSLF-LMNYVISGLI FT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >25/30-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------M-------NILYF------------- ---QAGLGVL------------ANNFLLCFYTFTIPG----H-----RPKPMDL-TSCQL -------TFAHIFFLITGGDNWLT------------DILESLNIETDFKCKTIFYTSRV- ---MRGFSIYITCLLSVF-------QAVTISPHTS-LLA-KFKHKLK------KYSIYT- VFYI--------WFFNFSINSH-IFYVGGFNNVSETNQ-MRVTKSCSLF-PMNYIISGLI FTVSTFRDVFLV-----------GVML-ITNAYIVIILFIHQRH----CKHLHSIRH--- ---LRLSPEKGPPR------------------------PSYYLWF-------------S- ----------------LWS------------------CTGWTSS---------------- ---S--YP--------------------------------PPS--CN------GCMT--- --------Q-------------------------------LS------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >12-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MFLLVFYIFIILG----H-----RPKPMDL-ISCQL -------SFVHIMMFLTGENFWLA------------DIFESLNVENDFKCKATFYTKRV- ---MRGLSICITCLLSVF-------QAVTISHRNS-LLA-KIKHRLK------KYMINA- LFYI--------WSFNLSFSSNLIFYVGGFTNVSQSKQ-LKVTKSCSLF-PINYIVRSLI LTVTTSRDMFLV-----------GVML-TTSTYMVIILCRHQRQ----CKHLH------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >12-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MT------------------SLSFMSSLLENILYF------------- ---QAGLGVL------------ANIFLLVFYIFIILG----H-----RPKPMDL-IFCQL -------TFVHIMMFLAGENFWLA------------DIFESLNVENDFKCKVTFYTKRV- ---MRGLSICITCLLSVF-------QAVIINHRNS-LMA-KIKDRLK------KYMINI- LFYI--------WSFNLSFSSNLIFYVGGFTNVSQTKQ-LKVTKSCSLF-PMNYIVRSLI LTVTTSRDMFLV-----------GIML-TTSTYMVIVLCRHQRQ----CKHLHSITPC-- ---LRASPETRATHIILLLVFFFVV---MYWVDFIISSTSILLWI----------YDPV- ----------------ILI------------------VQKFVVN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----T-SMVKNLQ--------------------------SQ------------------- -------------------CY--------------------------------------- ------------------------------------------------------------ ------------- >12.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLSFMPSLLENILYF------------- ---QAGLGVL------------ANIFLLVFYVFIILG----H-----RPKPMDL-ISCQL -------TFVHIMMFFAGENFWLA------------DIFESLNVENDFKCKATFYTKRV- ---MRGLSICITCLLSVF-------QAVMISHRNS-LLA-KIKHRLK------KYMINT- LFYI--------WSFNLSFSSNLIFYVGGFTNVSQTKQ-LKVTKSCSLI-PMNYIVRSLI LTVTTSRDMFLV-----------GIML-TTSTYMVIILCRHQRQ----CKHLHSITPC-- ---LRASPETRATHIILLLVFFFVV---MYWVDFIISFTSILLWI----------YDPV- ----------------ILI------------------VQKFVVN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----T-RMVKNLQ--------------------------SQ------------------- -------------------CY--------------------------------------- ------------------------------------------------------------ ------------- >12.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-ISCQL -------TFVHIMMFFAGENFWLA------------DIFESLNVENDFKCKATFYTKRV- ---MRGLSICITCLLSVF-------QAVMISHRNS-LLA-KIKHRLK------KYMINT- LFYI--------WSFNLSFSSNLIFYVGGFTNVSQTKQ-LKVTKSCSLI-PMNYIVRSLI LTVTTSRDMFLV-----------GIML-TTSTYMVIILCRHQRQ----CKHLHSITPC-- ---LRASPETRATHIILLLVFFFVV---MYWVDFIISFTSILLWI----------YDPV- ----------------ILI------------------VQKFVVN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----T-RMVKNLQ--------------------------SQ------------------- -------------------CY--------------------------------------- ------------------------------------------------------------ ------------- >12-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MT------------------SLFFMSSLLENILYF------------- ---QAGLGVL------------ANIFLLVFYIFIILG----H-----RPKPMDL-ISCQL -------TFVHIMMFLAGENFWLA------------DIFESLNVENDFKCKVTFYTKRV- ---MRGLSICITCLLSVF-------QAVMISHRNS-LLA-KIKHRLK------KYMINT- LFYI--------WSFNLSFSSNLIFYVGGFTNVSQTKQ-LKVTKSCSLF-PMNYIVRSLI LTVTTSRDMFLV-----------GIML-TTSTYMVIILCRHQRQ----CKHLHSITPC-- ---LRASPETRATHIILLLVFFFVV---MYWLDFIISFTSILLWI----------YDPV- ----------------ILI------------------VQKFVVN---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----T-SMVKNLQ--------------------------SQ------------------- -------------------CY--------------------------------------- ------------------------------------------------------------ ------------- >14-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SPSYMSSLLENILYF------------- ---QAGLGVL------------ANIFLLVFYIFIILG----Y-----RPKPMDL-ISCQL -------TFAHIMMFLAGENFLFA------------NIFESLNVENDFKCKATFYTKRV- ---MRGLSICITCLLSVI-------QAVTISHRNS-LLA-KFKHRLK------IYMINA- LFYI--------WTFNLSFSSNLIFYVGGFTNVSQTNQ-LKVTKSCSLL-PMNYIIRGLI LTVITSRDMFLV-----------GVML-TTSAYMVIFLFRHQRQ----CKHLHSISH--- ---LRASPEKRATQTILLLVF--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >14.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLSFMSSLLENILYF------------- ---QAGLGVL------------ANIFLLVFYIFIILG----H-----RPKPMDL-IFCQL -------TFVHIMMFLAGENFWLA------------NIFESLNVENDFKCKATFYTKRV- ---MRGLSICITCLLSVF-------QAVMISHRNS-LLA-KFKHKLK------IYMINA- LFYI--------WTFNLSLSSNLIFYVGGFTNMSQTKQ-LKVTKSCSLI-PMNYIVRGLI LTVISSRDMFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISH--- ---LRASPEKRATQTILLLVVFFVI---MYWVDFIISSTSILLWM----------YDPV- ----------------IMI------------------VQKLVVN---------------- ---A--YP-----------------------T-I--T---P--------------FV--- --------Q-------------------------------ISS-------DTR------V ----I-RVVKNWH--------------------------S-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >14.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLSFMSSLLENILYF------------- ---QAGLGVL------------ANIFLLVFYIFIILG----H-----RPKPMDL-IFCQL -------TFVHIMMFLAGENFWLA------------NIFESLNVENDFKCKATFYTKRV- ---MRGLSICITCLLSVF-------QAVMISHRNS-LLA-KFKHKLK------IYMINA- LFYI--------WTFNLSLSSNLIFYVGGFTNMSQTKQ-LKVTKSCSLI-PMNYIVRGLI LTVISSRDMFLV-----------GVML-TTSTYMVIILFRHQRQ----CKHLHSISH--- ---LRASPEKRATQTILLLVVFFVI---MYWVDFIISSTSILLWM----------YDPV- ----------------IMI------------------VQKLVVN---------------- ---A--YP-----------------------T-I--T---P--------------FV--- --------Q-------------------------------ISS-------DTR------V ----I-RVVKNWH--------------------------S-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >14.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MDL-ISCQL -------TFVHIMMFLAGENFWLA------------NIFESLNVENDFKCKATFYTKRV- ---MRGLSICITCLLSVF-------QAVMISHRNS-LLA-KFKHKLK------IYMINA- LFYI--------WTFNLSLSSNLIFYVGGFTNMSQTKQ-LKVTKSCSLI-PMNYIIRGLI LTVISSRDMFLV-----------GVML-TTSTYMVIILCRHQRQ----CKHLHSTSH--- ---LRASPEKRATQTILLLVVFFVI---MYWVDFIISSTSILLWM----------YDPV- ----------------IMI------------------VQKFVVN---------------- ---A--YP-----------------------A-I--T---P--------------FV--- --------Q-------------------------------ISS-------DTR------V ----I-RVVKNWH--------------------------S-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >14.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLSFMSSLLENILYF------------- ---QAGLGVL------------ANIFLLVFYIFIILG----H-----RPKPMDL-ISCQL -------TFVHIMMFLAGENFWLA------------NIFESLNVENDFKCKATFYTKRV- ---MRGLSICITCLLSVF-------QAVMISHRNS-LLA-KFKHKLK------IYMINA- LFYI--------WTFNLSLSSNLIFYVGGFTNMSQTKQ-LKVTKSCSLI-PMNYIIRGLI LTVISSRDMFLV-----------GVML-TTSTYMVIILCRHQRQ----CKHLHSTSH--- ---LRASPEKRATQTILLLVVFFVI---MYWVDFIISSTSILLWM----------YDPV- ----------------IMI------------------VQKFVVN---------------- ---A--YP-----------------------A-I--T---P--------------FV--- --------Q-------------------------------ISS-------DTR------V ----I-RVVKNWH--------------------------S-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >14-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SLSFMSSLLENILYF------------- ---QAGFGVL------------ANIFLLVFYIFIILC----H-----RPKPMDL-ISCQL -------TFVHIMMFLAGENFWLA------------NIFESLNVENDFKCKATFYTKRV- ---MRGLSICITCLLSVF-------QAVMISHRNS-LLA-KFKHKLK------IYMINA- LFYI--------WTFNLSFSSNLIFYVGGFTNMSQTKQ-LKVTKSCSLI-PMNYIVRGLI LTVISSRDMFLV-----------GVML-TTSTYMVIILCRHQRQ----CKHLHSISH--- ---LRASPEKKATQTILLLVVFFVI---MYWVDFIISSTSILLWM----------YDPV- ----------------IMI------------------VQKLVVN---------------- ---A--YP-----------------------A-I--T---P--------------FV--- --------Q-------------------------------ISS-------DTR------V ----I-RVVKNWH--------------------------S-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >14-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MT------------------SLSFMSSLLENILYF------------- ---QAGLGVL------------ANIFLLVFYIFIILG----H-----RPKPMDL-IFCQL -------TFVHIMMFLAGENFWLA------------NIFESLNVENDFKCKATFYTKRV- ---MRGLSICITCLLSVF-------QAVMISHRNS-LLA-KFKHKLK------KYMINT- LFYI--------WSFNLSFSSNLIFYVGGFTNVSQTKQ-LKVTKSCSLF-PMNYIVRGLI LTVMSSRDMFLV-----------GVML-TTSTYMVIILCRHQRQ----YKHLHSISH--- ---LRASPEKRATQTILLLVVFFVI---MYWVDFIISSTSILLWM----------YDPV- ----------------III------------------VQKLVVN---------------- ---A--YP-----------------------A-I--T---P--------------FV--- --------Q-------------------------------ISS-------DTR------V ----I-RVVKNWH--------------------------S-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >15-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SVE-------NVLYF------------- ---QAGFGVL------------PNVFLLLFYIFIILG----H-----RPKPTDL-ISCQL -------TLVHIIMFLTGGNIWLA------------DIFGFLNIENDIKCKATFYTSRV- ---TRGLSICITCLLSVF-------QAVTISPSTS-MLA-KFKQKLK------KYMNNA- LFYI--------WFFNLSVCSNMLFFVGGFTNVSETKQ-VKVTKSCSLF-PMNYIIRELI VILSTSRDVFLV-----------AVML-TTSAYMVNILHRHQRQ----YKHLHSIKS--- ---LRTSPEKKATQTILLLVVFFVV---MYWVDFIISFTSLLLWM----------YDPV- ----------------VLT------------------VQKFLIY---------------- ---A--YP-----------------------T-I--T---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-NVLKNLQ--------------------------SK------------------- -------------------CH--------------------------------------- ------------------------------------------------------------ ------------- >19.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSL-----------------NVR-------QLLHK------------- ---QSD-----------------------------------E-----RP----------L -------YLHHLPLECIPG-----------------------------------YHNQ-- -------------------------------SSTS-LLA-KFKSKVK------KHIIYA- FFYL--------WSFNLSFSIRWIFFVAGFTNVSENHQ-MKVTKSCSLF-PMNYIIRGLF LTVTMSRDICLV-----------GVML-ITSTYMVIILCRHQRQ----CKHLHSISY--- ---LRASPRKEPPKTILLLVVFFVV---MYWLDFIISFTSTLFWM----------YDPV- ----------------ILT------------------VQQFVMY---------------- ---A--YP-----------------------T-I--A---P--------------LV--- --------Q-------------------------------ISS-------DKR------I ----I-HILKKFTP-S----------------------ASR------------------- -------------------FSKK------------------------------------- ------------------------------------------------------------ ------------- >26.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MS------------------SIK-------NVLYF------------- ---QSGLGVL------------ANMFLLIFYIFIILG----H-----RPKPIDL-ISCQL -------NFVHIIMVLTAGDIWLS------------DLFESLNMENNFKCKAIFYINRV- ---MRGLSICITCLLSVF-------QIVTMSPSTS-FLA-KFKHTLK------KYIIYV- FFYF--------WLFNLSFSSNQLFSASAYTNVSDTNQ-MKISKYCSYF-PTNKIIRGLI LTVTTLRDVFLV-----------GVMV-TTSAYMVLFLFRHQRQ----CKHLHSINLI-- ---HDINKPKDKNHMIITL------------------------------NAEKA-FDK-- -------------------------------------IQ--------------------- ------NPF----------------------------------------------MI--- --------K-------------------------------VLE-------KSG------I LGPYL-NIIKEIY--------------------------SK------------------S VPNTKLNEEKLEAIPLKSGTRQGC----PLSPY--------------------------- ------------------------------------------------------------ ------------- >29.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MMFLAGGDIWLT------------DIFETLNIENDFKCKTIFYISRV- ---MRGLSICNTCLLSVV-------QAVTISPSTS-LLA-KFKPRLK------MYLIYA- SFCI--------WSFNLLYSSNQILYVGGFTNLSETNQ-MKVTKSCTLL-PKNYIIKGLI LTVSISRDIFLV-----------GVML-TTSTYMLNILFRHQRQ----CKHLHSINH--- ---LRASLRKGPPR------------------------PSYCWWF----SLCH------- ----------------VLGG-----------------LHHLI------------------ -------------------------------H-L--S---P--------------VM--- --------D-------------------------------V------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >18/28-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MF------------------SLE-------NVFYI------------- ---QAGLGVL------------ANMFLLFFYTSIILG----D-----RSKPMDL-ISCQL -------TFIHIMMILSEGDNLLA------------NILESLKFGNDVKCKTTFYINRV- ---MRGLSICITCLLSVF-------QAVTISPSTS-LLA-KFKKKQK------Q------ -------------------------------NQNQKNR-LFSAHYQASF------IAGLF SAVSQ-----LA-----------SISS-SLST----------------CAH--------- ------------------------------------------------------------ -------------------------------QG--------------------------- ------MP-----------------------------------------------LM--- --------H-------------------------------LS------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >11.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MQ--------------------N-------NFLHM------------- ---QGNERPL--------------------YL---------H-----HLPPECV-PGCH- ----------H------------------------------------------------- ------------------------------QSNTS-LLA-KFKHKLK------KYTINA- FFYI--------WSFNLSFSSNLIFYVGAYTNVSETNQ-MKVTKYCSLF-PMNYIIRGLI LTVTTSRDVFLV-----------GVML-ITSTYMVIILCRHQRQ----CKHLHSISH--- ---LRASPEKKG------------------------------------------------ ------------------------------------------------------------ ------HP-D---------------------H-L--A---AGDLLCGHVLGGLHHLI--- --------H-------------------------------LST-------VMD------V ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >46-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKA---------NILCTDTNMK-------VILFS------------- ---EVSVGIS------------ANSILFIAHLCMFLGE---N-----RPKPIDL-YIIFF -------SLTHLMLLVTIGLIAV-------------DIFMPGGRWDSTTCKFLMYLHIV- ---LRGPTLCATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF LFL---------CVLYMSLSSELL-SITAPLNLTSENF-LYVTQSCSIL-PMSYSRKSMF STKMAIREAFLI-----------GLMA-LSSGYMVAFLWSHKKQ----AQNLHSTRLS-- ---SKASPEQRATRTIMLLMSIFVV---FYILDSVIFYLRMKF-----------KDDSI- ----------------------------------FVCVQIIVSH---------------- ---S--FA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFFWSMC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >46-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKA---------NIFCTDTNMK-------VILFS------------- ---EVSVGIS------------ANSILFISHLCMFLGE---S-----RPKPIDL-YIAFF -------SLTHLMLLVTMGLIAV-------------DMFMPGGRWDSTTCTFLMYLHIV- ---LRGPTLCATCLLNVL-------WTITLSPRNS-CLT-KFKHKSP------HHISGAF LFL---------CVLYMSLSSELL-SITASLNLTSENF-LYVSQSCSIL-PMSYSIKSMF STKMAIREAFLI-----------GLMV-LSSGYMVALLWSHKKQ----AQHLHSNSLS-- ---LKASPEQRATRTIMLLMSFFVV---FYILDSVIFYSRMKF-----------KDDSI- ----------------------------------FVCVQIIVSH---------------- ---S--YV-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFFWSLC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >53-c ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MFGGF LLFASYP---HTMNKD---------NLLHIDTNIK-------ITLLA------------- ---EVSVGIS------------ANSILFIAYLCMFLGE---N-----RSKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMPWGRWDSTTCQSLIYLHRL- ---LRGLTLSATCLLNVL-------WTIALSPRSS-CLT-KFKHKSL------QHISCAF LFF---------CVLYMSFNSHFFISIIASPNLTLENF-MYVTQSCSLL-PLSYFRKSMF STPMAIREAFLI-----------SLMA-LSSGYMVALLWRHKKK----AQHLRSTSLS-- ---SKASPEQRATRTIMLLMSFFVV---FYILDTVIFHSRMKF-----------KDGSI- ----------------------------------LYCVQIIVSH---------------- ---S--YV-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFLRSMC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >44.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLLITMGLIAV-------------DMFMSQGRWDSTTCQSLIYLHRL- ---LRGLTLCATCLLNVL-------WTITLSSRSS-CLT-KFKHKYP------HHISGVF LFL---------CVLYMSFSSHFLV-ITGTPNLTSENF-LYVTQSCSLL-PMSYSRKSMF FMPVAIREAILI-----------GLMA-LSSGYMVAFLWKHKKQ----AQHLHSTSLS-- ---SKASPEQRATRTILLLMSFFVV---FYILDTVIFHSRMKF-----------KDGSI- ----------------------------------LYCIQIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFLRSMC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >44-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------MSFSSHFLLLITGTPNLTSENF-MYVTQSCSLL-PMSYSRTSMF STPVAIRETFLI-----------SLMA-LSSGYMVALLWRHKKQ----AQHLHSTSLS-- ---LKASPEERAIRSIMLLMGFFVV---LYILENVVFYSRMKF-----------KDGSI- ----------------------------------LYCVQIIVSH---------------- ---S--YV-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFLRSMC--------------------------GRIANI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >44.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------MSFSSHFLVSMTVTPNLTSENF-MYVTQSCSLL-PMSYSRTSMF STPVAIRETFLI-----------SLMA-LSSGYMVALLWRHKKQ----AQHLRSTSLS-- ---SKASPEQRATRTILLLMSFFVV---FYILDTVIFHSRMKF-----------KDGSI- ----------------------------------LYCFQIIVSH---------------- ---S--YV-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFLRSMC--------------------------GRIANI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >44.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKA---------NLLHIDTNIK-------ITLLA------------- ---EVSVGIS------------ANSILFIAYLCMLLGE---N-----RHKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMPWGRWDSTTCQSLIYLHRF- ---LRGLTLCATCLLNVL-------WTITLSSRNS-CLA-KFKHKYP------HHISGAF LFL---------CVLYMSFSSHFLVSMTVTPNLTSENF-MYVTQSCSLL-PMSYSRTSMF STPVAIRETFLI-----------SLMA-LSSGYMVALLWRHKKQ----AQHLRSTSLS-- ---SKASPEQRATRTILLLMSFFVV---FYILDTVIFHSRMKF-----------KDGSI- ----------------------------------LYCFQIIVSH---------------- ---S--YV-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFLRSMC--------------------------GRIANI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >44-x ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MFGGF LLFSSYP---HTMNKA---------NLLHIDTNIK-------ITLLA------------- ---EVSVGIS------------ANSILFIAYLCMLLGE---N-----RHKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMPRGRWDSTTCQSLIYLHRF- ---LRGLTLCATCLLNVL-------WTITLSSRNS-CLA-KFKHKYP------HHISGAF LFL---------CVLYMSFSSHFLLLITGTPNLTSENF-MYVTQSCSLL-PMSYSRTSMF STPVAIRETFLI-----------SLMA-LSSGYMVAFLWRHKKQ----AQHLRSTSLS-- ---SKASPEQRATRTILLLMSFFVV---FYILDTVIFHSRMKF-----------KDGSI- ----------------------------------LYCVQIIVSH---------------- ---S--YV-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFLRSMC--------------------------VRIANIRLF------------ -------SDG-------------------------------------------------- -------------------------------YGP-------------------------- ------------- >44-z ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MFGGF LLFSSYP---HTMNKA---------NLLHIDTNIK-------ITLLA------------- ---EVSVGIS------------ANSILFIAYLCMLLGE---N-----RPKPIDL-YVAFL -------SLTQLMLLITMGLIAV-------------DMFMPRGRWDSTTCQSLIYLHRF- ---LRGLTLCATCLLNVL-------WTITLSSRNS-CLA-KFKHKYP------HHISGAF LFL---------CVLYMSFSSHFLLLITGTPNLTSENF-MYVTQSCSLL-PMSYSRTSMF STPVAIRETFLI-----------SLMA-LSSGYMVAFLWRHKKQ----AQHLRSTSLS-- ---SKASPEQRATRTILLLMSFFVV---FYIFDTVIFHSRMKF-----------KDGSI- ----------------------------------LYCVQIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------M ----I-KFWGSKC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >44-c ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MFGGF LLFASYP---HTMNKD---------NLLHIDTNIK-------ITLLA------------- ---EVSVGIS------------ANSILFIAYLCMFLGE---N-----RSKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMPWGRWDSTTCQSLIYLHRF- ---LRGLTLCATCLLNIL-------WTITLSSRSS-CLT-KFKYKYP------HHISGAF LFL---------CVLYMSLSSHFLLLITGTPNLTSENF-MYVTQSCSLL-PMSYSRTSMF STAIAIRETFHI-----------SLMA-LCSGYMVALLWKHKKQ----AWDLHSTSLS-- ---SKASPVQRATRTIMLLMSFFVV---LYVLENAVFHSRMKF-----------KDGSI- ----------------------------------LYCVQIIASH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKR------M ----I-KFWGSMF--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >40-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MILGE---N-----RPKPIDL-YITFL -------SLTQLIFLITMGLIAV-------------DMFISQGIWDSTTCQSLIYLHRL- ---LRGLSLCATCLLNVL-------WTITLTSRSF-CST-KFKHKSP------HHISGAF IFF---------CVLYMSFSSHLFISIIATHNLTSEDF-MYVTQSCSIL-PMSYSRTSMF SAPMAIRETFLV-----------SLMA-LSSGYMVALLQRHQKQ----AQHLHSTSLS-- ---SKTSPEQRATRTIMLLMSFFVV---LYILENAVFYSRIKF-----------KDGSI- ----------------------------------LYCIQIILCH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFWESKC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >40.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKA---------NMLRTDKDMQ-------IILFS------------- ---EVSVGIS------------ANSILFIAHVCMILGE---N-----RPKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFLSQGIWDSTTCQSLIYLHRL- ---LRGLSLCATCLLNIL-------WTITLSSRSF-CST-KFKHKSP------HHISGAF IFF---------CVLYMSFSSHLFISIIATHNLTSENF-IYVTQSCSLL-PLSYSRTSMF SAPMAIREAFLV-----------SLMA-LSSGYMVALLWRHKKQ----AQHLHSTSLS-- ---SKASPEQRATRTILLLMSFFVV---LYILENAVFYSRIKF-----------KDGSI- ----------------------------------LYCVQIILCH---------------- ---S--YA-----------------------T-V--N---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFWESKC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >40.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------MF SAPMAIREAFLV-----------SLMA-LSSGYMVALLWRHKKQ----AQHLHSTSLS-- ---SKASPEQRATRTILLLMSFFVV---LYILENAVFYSRIKF-----------KDGSI- ----------------------------------LYCVQIILCH---------------- ---S--YA-----------------------T-V--N---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFWESKC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >40.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKA---------NILQTDTNMQ-------IILFS------------- ---EVSVGIS------------ANSILFIAHFCMTLGE---N-----RPKPINL-YIAFL -------SLTQLMLLITMGLIAV-------------DMLMSQGIWDSTTCQSLIYLHRL- ---LRGLTLCATCLLNVL-------WTITLSSRSF-CLT-KFKYKSP------HHISGAF LFF---------CALYMSFSSHLFLSIIATPNLTSEDF-MYVTQSCSVL-PMSYSRTSMF SVPMAIRETFLV-----------SLMA-LSSGYMVALLWRHKKQ----AQHLHSTSLS-- ---LKASPEERAIRSIMLLMGFFVV---LYILENVVFYSRMKF-----------KDGSI- ----------------------------------LYCVQIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------M ----I-KFWGSKC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >40-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTKA---------NILQTDTNMQ-------IILFS------------- ---EVSVGIS------------ANSILFIAHFCMTLGE---N-----RPKPINL-YIAFL -------SLTQLMLLITMGLISV-------------DMLMSQGIWDSTTCQSLIYLHRL- ---LRGLTLCATCLLNVL-------WTITLSSRSF-CLT-KFKYKSP------HHISGAF LFF---------CALYMSFSSHLFLSITATPNLTSEDF-MYVTQSCSVL-PMSYSRTSMF SVPMAIRETFLV-----------SLMA-LSSGYMVDLLWRHKKQ----AQHLHSTNLS-- ---SKASPEERATRSIMLLMGFFVV---LYILENVVFYSRMKF-----------KDGSI- ----------------------------------LYCVQIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------M ----I-KFWGSKC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >40-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTKA---------NILQTDTNMQ-------IILFS------------- ---EVSVGIS------------ANSILFIAHFCMTLGE---N-----RPKPINL-YIAFL -------SLTQLMLLITMGLISV-------------DMLMSQGIWDSTTCQSLIYLHRL- ---LRGLTLCATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF LFF---------CALYMSFSSHLFLSIIATPNLTSEDF-MYVTQSCSLL-PMSYSRTSMF SVPMDIRETFLV-----------SLMA-LSSGYMVDLLWRHKKQ----AQHLHSTSLS-- ---SKASPEKRATRSIMLLMGFFVV---LYILENVVFYSRMKF-----------KDGSI- ----------------------------------LYCVQIIVSH---------------- ---S--YV-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFL--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >40.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MTKA---------NILQTDTNMQ-------IILFS------------- ---EVSVGIS------------ANSILFIAHLCMILGE---N-----RTKPIDL-YIAFL -------SLTHLMLLITMGLIAV-------------DMFISRGRWDSTTCQSLIYLHRL- ---LRGLSLCATCLLNIL-------WTITLSSRSS-CLT-KFKHKSP------HHISGAF IFF---------CALYMSFSSHLFLSITGTPNLTSDNF-MYVTQSCSLL-PMSYSRTSMF SALMAIREAFLI-----------SIMA-LSSGYMVALLWRHKKQ----ARHLHSTSLS-- ---SKASPEQRATRTILLLMSFFVV---LYVLENAVFYSRMKF-----------KDGSI- ----------------------------------LYCVQIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------M ----I-KFWESMC--------------------------GRIVNP--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >40.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKA---------NLLYTDTNMK-------IFFIS------------- ---EVSVGIS------------ANSVLFIAHLCMILGE---N-----RPKPIDL-CIAFF -------SLTHLMLLITMGLIVA-------------DMFMSQGRWDSTTCKSLIYLHRL- ---LRGLTLSATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF IFF---------CALYMSFSSHLFLSITGTPNLTSDNF-MYVTQSCSLL-PMSYSRTSMF SALMAIREAFLI-----------SIMA-LSSGYMVALLWRHKKQ----ARHLHSTSLS-- ---SKASPEQRATRTILLLMSFFVV---LYVLENAVFYSRMKF-----------KDGSI- ----------------------------------LYCVQIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------M ----I-KFWESMC--------------------------GRIVNP--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >41-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MMNKA---------NLLYTDTNMK-------TFLFS------------- ---EVSVGIS------------ANSMLFIAHICIFLGE---N-----RPKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFISQGIWDSTTCQSLIYLHRL- ---LRGLTLCATCLLNVL-------WTITLSPRSF-CLT-KFKYKSP------YHISGAF IFF---------CAFYMSFSSHLFLSIIATLNLTSEDF-MYVTQSCSLL-PMSYSRTSMF STAIAIRETFHI-----------SLMA-LCSGYMVALLWKHKKQ----AWDLHSTSLS-- ---SKASPVQRATRTIMLLMSFFVV---LYVLENAVFHSRMKF-----------KDGSI- ----------------------------------LYCVQIIASH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKR------M ----I-KFWGSMF--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >41-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MMNKA---------NLLYTDTNMK-------TFLFS------------- ---EVSVGIS------------ANSMLFIVHICILLGE---N-----RPKPINL-YIAFL -------SLTQLMLLITMGLIVA-------------DMFMSQGIWDSITCQSLIYLHRL- ---LRGLTLCATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF LFF---------CALYMSFSSHLFLSIIATPNLTSEDF-MYVTQSCSLL-SMSYSRTSMF STAIAIREAFLI-----------SLFA-LCSGYMVALLWRHKKQ----AWDLHSTNVS-- ---SKSSPEQRATRTIMLLMSFFVV---LYVLENAVFHSRMKF-----------KDGSM- ----------------------------------LYCVQIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------L-------------------------------ICT-------EKR------M ----I-KFWGSMF--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >41-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MMNKA---------NLLYTDTNMK-------TFLFS------------- ---EVSVGIS------------ANSMLFIAHICILLGE---N-----RPKPINL-YIAFL -------SLTQLMLLMTMGLIVA-------------DMFMSQGIWDSITCQSLIYLHRL- ---LRGLTLCATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF LFF---------CALYMSFSSHLFLSIIATPNLTSEDF-MYVTQSCSLL-SMSYSRTSMF STAIAIREAFLI-----------SLFA-LCSGYMVALLWTHKKQ----AWDLHSTNLS-- ---SKSSPEQRATRTIMLLMSFFVV---LYVLENAVFHSRMKF-----------KDGSM- ----------------------------------LYCVQIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------L-------------------------------ICT-------EKR------K ----I-KFWGSMF--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >53-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKA---------NLLHTDINLK-------ITLFS------------- ---EVSVGIS------------ANSILIFAHLCMLLGE---N-----RPKPIDL-YIAFF -------SLTQLMLLITMGLIAV-------------DMFMPWGRWDSTTCQSLIYLHRL- ---LRGLTLSATCLLNVL-------WTITLSPRSS-YLT-KFKHKSL------QHISCAF LFL---------CVLYMSFNSHLFISIIAYPNLTLENF-MYVTQSCSLI-PLSYFRKSMF SIPMAIREALLI-----------GLMA-LSGGYMVAHLWRHKKQ----AQHLHRTSLS-- ---SKASPEQRATRTIMLLMSFFVV---LYILDLVIFHSRMKF-----------KDGSI- ----------------------------------LYGVQIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKR------I ----T-NFLRSMC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >44.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKA---------DLLHIDTNIK-------ITFLA------------- ---EVSVGIS------------ANSIVFFAHICKRLGE---N-----RPKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMSQGRWDSTTCKPLIYLHRL- ---LRGLTICATCLLNVL-------WTITLSSRNS-CLT-KFKHKYP------HHISGVF FFL---------CVLYMSFSSHFLVSLTATPNLTSKDF-MYVTQSCSLL-PMSYSRKSMF STPVAIRETFLI-----------SLMA-LSSGYMVTLLWKHKKQ----VRHLHSTSLS-- ---SKASPEQRATRTILLLMSFFVV---FYILSIVIFHSRMKF-----------KDGPI- ----------------------------------FYFVQIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFLRSVF--------------------------DRIKNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >44.3-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKA---------DLLHIDTNIK-------ITFLA------------- ---EVSVGIS------------ANSIVFFAHICKRLGE---N-----RPKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMSQGRWDSTTCKPLIYLHRL- ---LRGLTICATCLLNVL-------WTITLSSRNS-CLT-KFKHKYP------HHISGVF FFL---------CVLYMSFSSHFLVSLTATPNLTSKDF-MYVTQSCSLL-PMSYSRKSMF STPVAIRETFLI-----------SLMA-LSSGYMVTLLWKHKKQ----VRHLHSTSLS-- ---SKASPEQRATRTILLLMSFFVV---FYILDSVIFYSRMKF-----------KDGSI- ----------------------------------FVFVQIIVSN---------------- ---S--FA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFFWSVC--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >49-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKA---------NLLHTDTNMK-------ITLFS------------- ---EVSVGIS------------ANTILFFARLCKLLGE---N-----RPKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMPWERWDSTTCQLLIYLHRL- ---LRGLTLCATCLLNVL-------WTITLSPRSS-CLT-KFKHKSL------HNISGAF LFF---------CVLYVSFSSHVLVSIIATPNLTSEDF-VYVTHSCSLL-PMSYSRENRF ATLMAIRETFLI-----------SLMA-LSSGYMVALLWRHKKQ----VQYLHSTSLS-- ---SKASPEQRATRTILLLMSFFVV---LYTLERLVFQSRLKF-----------KDCSI- ----------------------------------FYFVHIIVSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFWESTF--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >49-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MK-------IILFS------------- ---EVSVGIS------------ANT----ARLCKLLGE---N-----KPKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMPWGRWDSTTCQSLIYLHRL- ---LRGLALSATCLLNVL-------WTITLSSRSS-CLT-KFKHKSP------HHISGAF LFF---------YVLYMSFSSHVFISIIATPNLTSEDF-MYVTQSCSLL-PMSYSRESRF STLMAIRETFLI-----------SLMA-LFSGYMVALLWRHKKQ----AQHLRSTSLS-- ---SKAFPEQRATRTIMLLMSLFVV---LYILERVVFQSRLKF-----------KDCSV- ----------------------------------FYFVHIIMSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFCESIF--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >49-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKA---------NLLHTDNNMK-------IILFS------------- ---EVSVGIS------------ANTILFFARLCKLLGE---N-----KPKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMPWGRWNSTTCQSLIYLHRL- ---LRGLALSATCLLNVL-------WTITLSSRSS-CLT-KFKHKSP------HHISGAF LFF---------YVLYMSFSSHVLVSIIVTPNLTSEDF-MYVTQSCSLL-PMSYSRESRF STLMAIRETFLI-----------SLMA-LSSGYMVALLWRHKKQ----AQHLRSTSLS-- ---SKASPEQRATRTIMLLTSLFVV---LYILERVVFQSRLKF-----------KDCSV- ----------------------------------FYFVHIIMSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFWESIF--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >49-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSEA---------NLLYTDNNMK-------IILFS------------- ---EVSVGIS------------ANTILFFARLCKLLGE---N-----KPKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFIPWGRWNSTTCQSLIYLHRL- ---LRGLALSATCLLNVL-------WTITLSSRSS-CLT-KFKHKSP------HHISGAF LFF---------NVLYMSFSSHVLVSIIATPNLTSEDF-MYVTQSCSLL-PTSYSRESRF STLMAIRETFLI-----------SLMT-LSSGYMVALLWRHKKQ----AQHLRSTSLS-- ---SKAFPEQRATRTIMLLMSLFVV---LYILERVVFQSRLKF-----------KDCSV- ----------------------------------FYFVHIIMSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFWESIF--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >49-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSEA---------NLLHTDNNMK-------IILFS------------- ---EVSVGIS------------ANTILFFARLCKLLGE---N-----KPKPIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMPWGRWNSTTCQSLIYLHRL- ---LRGLALSATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF LFF---------NVLYMSFSSHVLVSIIATPNLTSEDF-MYVTQSCSLL-PTSYSRESRF STLMAIRETFLI-----------SLMT-LSSGYMVALLWRHKKQ----AQHLRSTSLS-- ---SKAFPEQRATRTIMLLMSLFVV---LYILERVVFQSRLKF-----------KDCSV- ----------------------------------FYFVHIIMSH---------------- ---S--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------ICT-------EKH------I ----I-KFWESIF--------------------------GRIVNI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >50.2-s ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------MFGGF LLFPSYP---HTMNKA---------NLLHIDTNIK-------ITLLA------------- ---EVSVGIS------------ANSILFIAYLCMLLGE---N-----RHKLIDL-YIAFL -------SLTQLMLLITMGLIAV-------------DMFMPWGRWDSTTCQSLIYLHRL- ---LRGLALSATCLLNVL-------WTITLSSRSS-CLT-KFKHKSP------HHISGAF LFF---------CVLYMSFSSHLLVSIIATFNSTSDNF-LYVTQSCSIL-PVSYSRTSIL STMMTMREAFLI-----------GLMA-LSSGYVVVLLWRHKKQ----ARHLHSTSLS-- ---SKASPEQRATRTIMLLMGFFVV---LYILDTVIFQARLKF-----------KDVST- ----------------------------------FFCVKIIMSH---------------- ---S--YA-----------------------T-F--S---P--------------FV--- --------F-------------------------------ICN-------DKY------M ----I-KFVTSMC--------------------------GRIVNV--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >50.4-s -M---------------------------------------------------------- ------------------------------------------------------------ --------------------------------------------------SQLRNRVARF LLFASYP---HTMSKA---------NLLHTDNNMK-------ITLFS------------- ---EVSVGIS------------ANSILFVVHLCKLLHE---N-----KPKPIDL-YVAFF -------SITQLMLLITMGLIAV-------------DMFMPWGRWDSTTCQSLIYLHRL- ---LRGLTFCATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF LFF---------CVLYMSFSSHLLVSIIATFNSTSDNF-LYVTQSCSIL-PVSYSRTSIL STMMTMREAFLI-----------GLMA-LSSGYVVVLLWRHKKQ----ARHLHSTSLS-- ---SKASPEQRATRTIMLLMGFFVV---LYILDTVIFQARLKF-----------KDVST- ----------------------------------FFCVKIIMSH---------------- ---S--YA-----------------------T-F--S---P--------------FV--- --------F-------------------------------ICN-------DKY------M ----I-KFVTSMC--------------------------GRIVNV--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >50-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKA---------NLLHTDNNMK-------ITLFS------------- ---EVSVGIS------------ANSILFVVHLCKLLHE---N-----KPKPIDL-YIAFF -------SITQLMLLITMGLIAV-------------DMFMPWGRWDSTTCQSLIYLHRL- ---LRGLTFCATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF LFF---------CVLYMSFSSHLLVSIIATFNSTSDNF-LYVTQSCSIL-PVSYSRTSIL STMMTMREAFLI-----------GLMA-LSSGYVVVLLWRHKKQ----ARHLHSTSLS-- ---SKASPEQRATSTIMLLMGFFVV---LYILDTVIFQARLKF-----------KDVST- ----------------------------------FFCVKIIISH---------------- ---S--YA-----------------------T-F--S---P--------------FV--- --------F-------------------------------ICN-------DKY------M ----I-KFVTSMC--------------------------GRIVNV--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >50-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKA---------NLLHTDNNMK-------ITLFS------------- ---EVSVGIS------------ANSILFVVHLCKLLHE---N-----KPKPIDL-YVAFF -------SITQLMLLITMGLIAL-------------DMFMPWGRWDSTTCQSLFYLHRL- ---LRGLTFCATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF LFF---------CVLYMSFSSHLLVSIIATFNSTSDNF-LYVTQSCSIL-PVSYSRTSIL STMMTMREAFLI-----------GLMA-LSSGYVVVLLWRHKKQ----ARHLHSTSLS-- ---SKASPEQRATRTIMLLMGFFVV---LYILDTVIFQARLKF-----------KDVST- ----------------------------------FFCVKIIMSH---------------- ---S--YA-----------------------T-F--S---P--------------FV--- --------F-------------------------------ICN-------DKY------M ----I-KFVTSMC--------------------------GRIVNV--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >50-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKA---------NLLHTDNNMK-------ITLFS------------- ---EVSVGIS------------ANSILFVVHLCKLLHE---N-----KPKPIDL-YVAFF -------SITQLMLLITMGLIAL-------------DVFMPWGRWDSTTCQSLIYLHRL- ---LRGLTFCATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF LFF---------CVLYMSFSSHLLVSIIATFNSTSDNF-LYVTQSCSIL-PVSYSRTSIL STMMTMREAFLI-----------GLMA-LSSGYVVVLLWRHKKQ----ARHLHSTSLS-- ---STASPEQRATRTIMLLMGFFVV---LYILDTVIFQARLKF-----------KDVST- ----------------------------------FFCVKIIMSH---------------- ---S--YA-----------------------T-F--S---P--------------FV--- --------F-------------------------------ICN-------DKY------M ----I-KFVTSMC--------------------------GRIVNV--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >50.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKA---------NLLHTDNNMK-------ITLFS------------- ---EVSVGIS------------ANSILFVVHLCKLLHE---N-----KPKPIDL-YVAFF -------SITQLMLLITMGLIAV-------------DMFMPWGRWDSTTCQSLIYLHRL- ---LRGLALSATCLLNVL-------WTITLSSRSS-CLT-KFKHKSP------HHISGAF LFF---------CVLYMSFSSHLLVSIIATFNSTSDNF-LYVTQSCSIL-PVSYSRTSIL STMMTMREAFLI-----------GLMA-LSSGYVVVLLWRHKKQ----ARHLHSTSLS-- ---SKASPEQRATRTIMLLMGFFVV---LYILDTVIFQARLKF-----------KDVST- ----------------------------------FFCVKIIMSH---------------- ---S--YA-----------------------T-F--S---P--------------FV--- --------F-------------------------------ICN-------DKY------M ----I-KFVTSMC--------------------------GRIVNV--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >40.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKA---------NILQTDTNMQ-------IILFS------------- ---EVSVGIS------------ANSILFIAHFCMTLGE---N-----RPKPINL-YIAFL -------SLTQLMLLITMGLIAV-------------DMLMSQGIWDSTTCQSLIYLHRL- ---LRGLTLCATCLLNVL-------WTITLSSRSF-CLT-KFKYKSP------HHISGAF LFF---------CALYMSFSSHLFLSIIATPNLTSEDF-MYVTQSCSVL-PMSYSRTSMF SVPMAIRETFLV-----------SLMP-CPVG----TWW-----------------LSYG --GTRSRP---------------------------------------------------- ------------------------------------------------------------ ---S--TF-----------------------T-A--P---A--------------FL--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >50.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSKA---------NLLHTDNNMK-------ITLFS------------- ---EVSVGIS------------ANSILFVVHLCKLLHE---N-----KPKPIDL-YVAFF -------SITQLMLLITMGLIAV-------------DMFMPWGRWDSTTCQSLIYLHRL- ---LRGLTFCATCLLNVL-------WTITLSPRSS-CLT-KFKHKSP------HHISGAF LFF---------CVLYMSFSSHLLVSIIATFNSTSDNF-LYVTQSCSIL-PVSYSRTSIL STMMTMREAFLI-----------GLMA-LSSGYVVVLLWRHKKQ----AVIFTAPVFLQK HPQSKEPPGPSCCSWASLWFS--------------TFWTQLFS-----------KQG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >42-c ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSEI LFFSTQSMFSHTMNKN---------SRLHTHSIIG-------KTFFS------------- ---EIGIGIS------------GNSFLLLFHILKFMRG---N-----RPRLIDL-PIGLL -------SLIHLLMLLVAAFIAT-------------DIFISWRDWDDITCKFLVYLYRV- ---LRGFSLCTTSMLSVL-------QAIILSPRSS-CLA-KFKHISP------HHILCAI LFL---------SVLYMLISSQLLVSIIATPNLTMNDF-IYVTQSCSIL-PLSYLMQSIY STLLAIREFFLI-----------SLMV-LSNWYMVALLCMHRKQ----TQNLHGTNLS-- ---PKKSPEQSATQTILMIMSFFVL---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYSMELFIMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MSI-------EKH------I ----V-NFLRSLG--------------------------KRVI----------------- -----------------------------------NLNLH-------------------- ------------------------------------------------------------ ------------- >42-p ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSEI LFFSPQPLFSHTMDKN---------SRLHTNSKIG-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHTLRFIRG---H-----RPRLTDL-PIVLL -------SLIHLLMLLVAAFIAT-------------DIFISWRGWDDIICKLLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KLKHISP------HHISGAI LFL---------SVLYMLISSQLLVSIIATPNLTMNDF-IYVTQSCSIL-PLSYLMQSIY STLLTIREFFLI-----------SLMV-LSNWYMVALLCMHRKQ----TQHLQGTSLS-- ---PKKSPEQSATQTILMLMSFFVL---MTIYDTMVSCSRTMF-----------LNDPT- ----------------------------------SYSIELFIMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NFLRSIG--------------------------KRVI----------------- -----------------------------------NLNLH-------------------- ------------------------------------------------------------ ------------- >42.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLSIL-------QAIILSPRSS-CLA-KFKHISP------HHISGAI LFL---------SVLYMLIGSQLLVSIIATPNLTMNDF-IYVTQSCSIL-PLSYLMQSIY STLLAIREFFLI-----------SLMV-LSNWYMVALLCMHRKQ----TQHLHGTNLS-- ---P-KIPEQSATQTILMLMSFFVL---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYSIELFIMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >42.3-s ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------M LFL----------------------------SLYV-------RTFFS------------- ---EIGIGIS------------GNSFLLLVHILKFIRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAFIAT-------------DIFISRRGWDDIICKFLVYLYRV- ---LRGFSLCTTSMLSIL-------QAIILSPRSS-CLA-KFKHISP------HHISGAI LFL---------SVLYMLIGSQLLVSIIATPNLTMNDF-IYVTQSCSIL-PLSYLMQSIY STLLAIREFFLI-----------SLMV-LSNWYMVALLCMHRKQ----TQHLHGTNLS-- ---PQKSPEQSATQTILMLMSFFVL---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYSIELFIMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >42.1-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MGDV LFFSPQSMFSHTMNKN---------SILHTHSIIG-------KTFFS------------- ---EIGIGIS------------GNSFLLLVHILKFIRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAFIAT-------------DIFISRRGWDDIICKFLVYLYRV- ---LRGFSLCTTSMLSIL-------QAIILSPRSS-CLA-KFKHISP------HHISGAI LFL---------SVLYMLIGSQLLVSIIATPNLTMNDF-IYVTQSCSIL-PLSYLMQSIY STLLAIREFFLI-----------SLMV-LSNWYMVALLCMHRKQ----TQHLHGTNLS-- ---PQKSPEQSATQTILMLMSFFVL---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYSIELFIMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NFLRSLG--------------------------KRVI----------------- -----------------------------------NFNLH-------------------- ------------------------------------------------------------ ------------- >42-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MGDI LFSSPQSMFSHTMNKN---------SILHTHSIIG-------KTFFS------------- ---EIGIGIS------------GNSFLLLVHILKFIRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAFIAT-------------DIFISRRGWDDIICKFLVYLYRV- ---LRGFSLCTTSMLSIL-------QAIILSPRSS-CLA-KFKHISP------HHISGAI LFL---------SVLYMLIGSQLLVSIIATPNLTMNDF-IYVTQSCSIL-PLSYLMQSIY STLLAIREFFLI-----------SLMV-LSNWYMVALLSMHRKQ----TQHLHGTNLS-- ---PKKSPEQSATQTILMLISFFLL---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYSIELFIMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NFLRSLG--------------------------KRVI----------------- -----------------------------------NFNLH-------------------- ------------------------------------------------------------ ------------- >42.4-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRR-----------YM---- ------LELCTTSMLSIL-------QAIILSPRSS-CLA-KFKHISP------HHISGAI LFL---------SVLYMLIGSQLLVSIIATPNLTMNDF-IYVTQSCSIL-PLSYLMQSIY STLLAIREFFLI-----------SLMV-LSNWYMVALLCMHRKQ----TQHLHGTNLS-- ---PQKSPEQSATQTILMLMSFFVL---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYSIELFIMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NFLRSLG--------------------------KRVI----------------- -----------------------------------NFNLH-------------------- ------------------------------------------------------------ ------------- >42-x ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MGDI LFFSPQSMFSHTTNKN---------SRLHTHPNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLLMAFMAT-------------DIFISQRGWDDIICKFLVYLYGV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KFKHISP------HHISGAI LFL---------SVLYMLISSQLLVSIIATPNLTMNDF-IYVTQSCSIL-PLSYLMQSIY STLLAIREFFLI-----------SLMV-LSNWYMVALLCMHRKQ----TQHLHGTNLS-- ---PQKSPEKSATQTILMLMSFFVM---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYSIELFIMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NFLRSLG--------------------------KRVI----------------- -----------------------------------NFNLH-------------------- ------------------------------------------------------------ ------------- >43.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLLVAAFIAT-------------DIFISWRDWDDITCKFLVYLYRV- ---LRGFSLCTTSMLSVL-------QAIILSPRSS-CLA-KFKHISP------HHILCAI LFL---------SVLYMLISSQLLVSIIATPNLTTNNF-LYVTQSCSIL-PLSYLLKRIN SMLLAIREFFLI-----------SPMV-LSTWYMVALLCMHRKH----TQHLQETRLS-- ---LKKSPEQSAIQTILMHMSFFVL---MTIYDNIVSCLRTMF-----------LNDPI- ----------------------------------SYSIEHFMIH---------------- ---L--YA-----------------------T-V--S---P--------------FV--- --------L-------------------------------MSN-------ETH------I ----V-TFLKSIG--------------------------KRMI----------------- -----------------------------------NLNLH-------------------- ------------------------------------------------------------ ------------- >43.2-c ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSNI LFFSPWSLFSHTMNKN---------SRLHTNSNIG-------NILFS------------- ---EIGIGIT------------GNSFLLLFHILKFIRG---N-----RPRLTDL-PIGLL -------SLIHLLMLLVAAFIAT-------------DIFISWRDWDDITCKFLVYLYRV- ---LRGFSLCTTSMLSVL-------QAIILSPRSS-CLA-KFKHISP------HHILCAI LFL---------SVLYMLISSQLLVSIIATPNLTTNNF-IYVTQSCSIL-LLSYLVKSIN SMLLAIREFFLI-----------SLMV-LSTWYMVALLCMHRKQ----TQHLQETRLY-- ---LKKSPEQSAVQTILMLMSFFVV---MNIYDNIVPCLRTMF-----------LNDPI- ----------------------------------PYSIELFMIH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MSN-------EKH------I ----V-TFLKSIG--------------------------KRMI----------------- -----------------------------------NLNLH-------------------- ------------------------------------------------------------ ------------- >43.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLSVL-------QAIILSPRSS-CLA-KFKHISL------HHILCAI LFL---------SVLYMLISSQLLVSIIATPNLTTNDL-TYVTQSCYIL-PLSYLVESIN STLLAIREYFLI-----------SLMF-LSTWYIVALLCMHRKQ----TQHLQETRLS-- ---LKKSPEKSATQTILMLMTFFVL---MTIYDNIVSCLRTML-----------LNDPT- ----------------------------------SYSIELFMIH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MSN-------E--------- ------------------------------------------------------------ -------------------------------------NI--------------------- ------------------------------------------------------------ ------------- >43.2-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSKI LFFSPCSLFSHTMNKN---------SRLHTNSNIG-------NTFFS------------- ---EIGIGIT------------GNSFLLLYHILKFIRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAFIAT-------------DIFISRRGWDDIICKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KFKHISL------HHILCAI LFL---------SVLYMLISSQLLVSIIATPNLTTNDL-TYVTQSCYIL-PLSYLVESIN STLLAIREYFLI-----------SLMF-LSTWYIVALLCMHRKQ----TQHLQETRLS-- ---LKKSPEKSATQTILMLMTFFVL---MTIYDNIVSCLRTML-----------LNDPT- ----------------------------------SYSIELFMIH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MSN-------EKH------I ----V-NFLRSMG--------------------------KRMI----------------- -----------------------------------NLNLH-------------------- ------------------------------------------------------------ ------------- >43-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSKI LFFSPCSLFSHTMNKN---------SRLHTNSNIG-------NTFFS------------- ---EIGIGIT------------GNSFLLLYHILKFIRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAFIAT-------------DIFISRRGWDDIICKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLS-KFKHISL------HHILCAI LFL---------SVLYMLISSQLLVSIIATPNLTTNDL-TYVTQSCSIL-PLSYLVESIN STLLAIREYFLI-----------SLMF-LSTWYIVALLCMHRKQ----TQHLQETRLS-- ---LKKSPEQSATQTILMLMTFFVL---MTIYDNIVSCLRTML-----------LNDPT- ----------------------------------SYSIELFMIH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MSN-------EKH------I ----V-NFLRSMG--------------------------KRMI----------------- -----------------------------------NLNLH-------------------- ------------------------------------------------------------ ------------- >43-z ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSKI LFFSPCSLCSHTMNKN---------SRLHTNSNIG-------NTFFS------------- ---EIGIGIT------------GNSFLLLFHIIKFIRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAFIAT-------------DIFISRRGWDDIICKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLS-KFKHISL------HHILCAI LFL---------SVLYMLISSQLLVSIIATPNLTTNDL-TYVTQSCSIL-PLSYLVESIN STLLAIREYFLI-----------SLMF-LSTWYIVALLCMHRKQ----TQHLQETRLS-- ---LKKSPEQSATQTILMLMTFFVL---MTIYDNIVSCLRTML-----------LNEPT- ----------------------------------SYSIELFLIH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MSN-------EKH------I ----V-NFLRSMG--------------------------KRMI----------------- -----------------------------------NLNLH-------------------- ------------------------------------------------------------ ------------- >42/43-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSEI LFFSPQPLFPCTMNKN---------SRLHTNFNIG-------NIFFS------------- ---EIGIGIS------------GNSFLLLFNILKFIRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAFIAT-------------DIFISRRGWDDIICKFLVYLYRV- ---LRGFSLCTTSMLSVL-------QAIILSPRSS-CLA-KFKHKSP------HHISCTI IFL---------SVLYMLIGSHLL-SIIATPNLTTNDF-IYIIQSCSIL-SLSYLMQSIY STLVAIREVFLI-----------SLMV-LSTWYMVALLCMYRKQ----TQHLQGSRLS-- ---QKNSPEQSATQIILMLMSFFVL---MTIYDIMVCCSRAMF-----------LNDPT- ----------------------------------SYSIKLFIMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NFLRSLG--------------------------KRVI----------------- -----------------------------------NFNLH-------------------- ------------------------------------------------------------ ------------- >48-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPSSS-CLA-KFKRKSP------HNISCAI IFP---------SVLYMSISSHLFISITATPNLTMNDF-LYVSQSCSLL-PLSYLMKSMY STLLVLREVFLI-----------GLMV-LSNSYMVALLCMHRKQ----AQHLQSTSLS-- ---LKASAEQRATQTILMLMTFFVL---MSIFDSIVSCSRTMF-----------LDDPT- ----------------------------------SYSIHIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >47.6-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLHRS- ---LRGLSLCTTSMLSVL-------QAIILSPRIS-YLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-FYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKTAPEQRATQTS-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >47.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLHRS- ---LRGLSLCTTSMLSVL-------QAIILSPRIS-YLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-FYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKTAPEQRATQTILMLMTFFVL---MSTFDSIVSSSRTMF-----------LDDQT- ----------------------------------CYSLYIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------L ----V-NFLRSMG--------------------------EWII----------------- -----------------------------------NM----------------------- ------------------------------------------------------------ ------------- >47.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RPRLTDL-PIVLL -------SLIHLLMLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRIS-YLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-LYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKTAPEQRATQTILMLMTFFVL---MSTFDSIVSSSRTMF-----------LDDPT- ----------------------------------CYSLYIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKN------L ----V-NFLRSMC--------------------------ECII----------------- -----------------------------------NM----------------------- ------------------------------------------------------------ ------------- >47.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RPRLTDL-PIVLL -------SLIHLLMLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRIS-YLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-LYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKTAPEQRATQTILMLMTFFVL---MSTFDSIVSSSRTMF-----------LDDPT- ----------------------------------CYSLYIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKK------F ----S------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >48-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRRC-CLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNDF-LYVSQSCSLL-PLSYLMQSIY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKASAEQRATQTILMLMTFFVL---MSIFDSIVSCSRTMF-----------LDDPT- ----------------------------------SYSIHIFVMH---------------- ---I--YA-----------------------I-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >48-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRSY-CLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLLISITATPNLTMNDF-LYVSQSCSLL-PLSYLMQSIY STLLVLREVFLI-----------GLMV-LSTSYMVALLYMHRKQ----AQNLQGTSLS-- ---LKASAEQRATQTILMLMTFFVL---MSIFDSIVSCSRTMF-----------LDDPT- ----------------------------------SYSIHIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------IST-------EKH------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >47.8-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRSC-CLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-LYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKTAPEQRATQTILMLMTFFVL---MS------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >47.4-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RSRLTDL-PIGLL -------SLIHLLMLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRSC-CLA-KFKHKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-LYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKTAPEQRATQTILMLMTFFVL---MSTFDSIVSSSRTMF-----------LDDPT- ----------------------------------CYSLYIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------L ----V-NFLRSMG--------------------------EWII----------------- -----------------------------------NM----------------------- ------------------------------------------------------------ ------------- >47.9-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RSRLTDL-PIGLL -------SLIHLLMLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRSC-CLA-KFKHKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-LYVSQSCSLY-P--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >47-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRSY-CLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLFISITATLNLTMNNF-LYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKASAEQRATQTILMLMTFFVL---MSIFDSIVSSSRAMF-----------LDDST- ----------------------------------CYSIYIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------L ----V-NFFRSMC--------------------------EWII----------------- -----------------------------------NM----------------------- ------------------------------------------------------------ ------------- >47/48-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLYHIIKFFRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAFIAT-------------DIFISRRGWDDIICKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSC-CLA-KFKRKSS------HNISCAI IFL---------IVLYMSISSHLFISITATPNLTVNNF-LYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >48.1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLLVAAVIAT-------------DIFISRRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRIS-YLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-LYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKTAPEQRATQTILMLMTFFVL---MSILDSIVSCSRAMF-----------LDDPT- ----------------------------------SYSIHIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >48.2-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLLVAAVIAT-------------DIFISRRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRSC-CLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-LYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKTAPEQRATQTILMLMTFFVL---MSILDSIVSCSRAMF-----------LDDPT- ----------------------------------SYSIHIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >45-p ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSEI LFFSPQPLFLHMMNKN---------SRFHTHSNIK-------NTFFL------------- ---EIGIGIS------------GNSFLLLFHIRKFIRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVMAFIAT-------------DIFISWREWDDIICKFLVYLYRV- ---LRGLSLCTISMLSVL-------QAIILSPRSS-CLA-KFKHKSH------HHISRGI IFL---------SVLYMLISSHILLSIIATPNLTRNDF-LYVTQSCSIL-PLSYLMQSMY STLLALREFFLI-----------SLMV-LSTLYMVVLLCRHRKQ----AQNLQGTSLS-- ---LKASAEQRATQTILMLMTFFVL---MSIFDSIVSCSRTMF-----------LDDPT- ----------------------------------SYSIHIFVMH---------------- ---I--YT-----------------------T-V--S---P--------------FV--- --------F-------------------------------IST-------EKQ------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >45.2-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSEI LFFSPHPLFSHMMNKN---------SRLHTHSNIK-------NTLFS------------- ---EIGIGIL------------GNSFLLLFHILKFIRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLLMAFIAT-------------DIFISCRGWDDITCKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KLKHKSP------HHISCAI IFL---------SVLYMLISSHILLSIIATPNMTRNDF-LYVTQSCSIL-PLSYVMQSTY STLLALREVFLI-----------SLMV-LSTLYMVVLLCRHRKQ----AQHLQGTNLS-- ---LKASAEQRATQTILMLMTFFVL---MSIFDSIVSCSRTMF-----------LDDPT- ----------------------------------SYSIHIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >45.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLSVL-------QAIILSPRSS-CLA-KLKHKYP------HHISCAI IFL---------SVLYMLISSHILLSIIATPNLTRNDF-LYVTQSCSIL-PLSYVMQSMY STLLALREVFLI-----------SLMV-LSTLYMVVLLCRHRKQ----AQHLQGTSLS-- ---PKASAEQRATQTILMLMTFFVL---MSIFDSIVSCSRTMF-----------LDDPT- ----------------------------------SYSIHIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >45.2-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSEI LFFSPQPLFSHMMNKN---------SRLHTHSNIK-------NTFFS------------- ---EIGIGIL------------GNSFLLLFHILKFIRG---H-----RLRLTDL-PIGLL -------SLIHLLMLLLMAFIAT-------------DIFISRRGWDDIICKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KLKHKYP------HHISCAI IFL---------SVLYMLISSHILLSIIATPNLTRNDF-LYVTQSCSIL-PLSYVMQSMY STLLALREVFLI-----------SLMV-LSTLYMVVLLCRHRKQ----AQHLQGTSLS-- ---PKASAEQRATQTILMLMTFFVL---MSIFDSIVSCSRTMF-----------LDDPT- ----------------------------------SYSIHIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >45-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLLLMAFIAT-------------DIFISRRGWDDIICKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KLKHKSP------HHISCAI IFL---------SVLYMLISSHILLSITATPNLTMNDF-LYVSQSCSLL-PLSYLVQSMY STLLALREVFLI-----------SLMV-LSTLYMVVLLCRHRKQ----AQHLQGTSLS-- ---FKASAEQRATQTILMLMTFFVL---MSIFDSIVSCSRTMF-----------LDDPT- ----------------------------------SYSIHIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >45.1-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MSEI LFFSPQPLFSHMTNKN---------SRLHTHSNIK-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHILKFIRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLLMAFIAT-------------DIFISRRGWDDIICKFLVYLYGV- ---LRGLSLCTTSMLSVL-------QAIILSPRSY-CLA-KLKHKSP------HHISCAI IFL---------SVLYMLISSHILLSIIATPNLTRNEF-LYVTQSCSRL-PLSYLVQSMY STLLALREVFLI-----------SLMV-LSTLYMVVLLCRHRKQ----AQHLQGTSLS-- ---FKASAEQRATQTILMLMTFFVL---MSIFDSIVSCSRTMF-----------LDDPT- ----------------------------------SYSIHIFAMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NILRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >45.1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLLVAAVIAT-------------DIFISRRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KLKHKSP------HHISCAI IFL---------SVLYMLISSHILISITATPNLTMNDF-LYVSQSCSLL-PLSYPVQSMY STLLALREVFLI-----------SLMV-LSTLYMVVLLCRHRKQ----AQHLQGTSLS-- ---FKASAEQRATQTILMLMTFFVL---MS------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >45.2-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLLVAAVIAT-------------DIFISRRGWNDIICKFLVYLYRS- ---LRGLSLCTTSMLSVL-------QAIILSPRIS-YLA-KFKHKSP------HHISCDI IFL---------SVLYMLIGSHILVSIIATPNLTRNDF-LYVTQSCSIL-PLSYVMQSMY STLLALRKVFLI-----------SLMV-LSTSYMVVLLYRHRKQ----AQHLQGTSLS-- ---LKASAEKRATQTILMLMTFFVL---MS------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >47/48-p -----------------------------------------------MVRG--------- ------------------------------------------------------------ --------------------------------------------------AELPRKMSEI LFFSPQPFFSLVMNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFIRG---H-----RSRLTDL-PIGLL -------SLIHILMLLVAAFIAT-------------DIFNSWRAWDDTICKFLVYLYRV- ---LRGLSLCTISMLSVL-------QAIILSPRSS-CLA-KLKHKSL------HHISCAI IFL---------SVLYMSISSHLLISIIATPNLTTNNF-LYVSQSCSIL-PLSYLMQSIY STLLVIREVFLI-----------GLMV-FSTSYMVALLSMHRKQ----VQNLHGTRFS-- ---LKSAPEQRATQTILMLMIFFVL---MSIFDSIVSCSRTMF-----------LDDPT- ----------------------------------CYSLHIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------L ----L-NFLRSMG--------------------------ER------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >47.7-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEN---------SRLHTHSNIR-------NTFFS------------- ---EIGIGIS------------GNSFLLLFHIIKFFRG---H-----RPRLTDL-PIGLL -------SLIHLLMLLVAAVIAT-------------DIFISWRGWNDIICKFLVYLHRS- ---LRGLSLCTTSMLSVL-------QAIILSPRIS-YLA-KFKRKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-F-------------------- ------------------------------------------------------------ -----------------------------------------MF-----------L----- ------------------------------------------------------------ ------------------------------------S---P--------------AL--- --------F-------------------------------YP------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >51-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MMNEN---------SRVHTHSNLR-------HIFFS------------- ---EIGIGIS------------GNSFLLLFHILKFIHG---H-----RSRLSDL-PIGLL -------SLIHLLMLLVMAFIAT-------------DIFISWRGWDDIICKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KFKRKSL------HHISCAI LFL---------SVLYMLIGSQLLVSIIATPNLTTNDF-IYVTQSCSIL-PLSYVMQSMF STLLVIRDVFLI-----------SLMV-LSTWYMVALLCRHRKK----TQHLQGTSLS-- ---PKTSPKQRATQTLLMLMSFFVL---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYNMQIFVVH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NCLRSV------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >51-x ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MNEI LFFSPQPLFSHMMNEN---------SRVHTHSNLR-------HIFFS------------- ---EIGIGIS------------GNSFLLLFHILKFIHG---H-----RSRLSDL-PIGLL -------SLIHLLMLLVMAFIAT-------------DIFISWRGWDDIICKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KFKRKSL------HHISCAI LFL---------SVLYMLIGSQLLVSIIATPNLTTNDF-IYVTQSCSIL-PLSYVMQSMF STLLVIRDVFLI-----------SLMV-LSTWYMVALLCRHRKK----TQHLQGTSLS-- ---PKTSPKQRATQTLLMLMSFFVL---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYNMQIFVVH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NCLRSV------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >51-z ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MNEI LFFSPQPLFSHMMNEN---------SRVHTHSNLR-------HIFFS------------- ---EIGIGIS------------GNSFLLLFHILKFIHG---H-----RSRLSDL-PIGLL -------SLIHLLMLLVMAFIAT-------------DIFISWRGWDDIICKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KFKRKSL------HHISCAI LFL---------SVLYMLIGSQLLVSIIATPNLTTNDF-IYVTQSCSIL-PLSYVMQSMF STLLVIRDVFLI-----------SLMV-LSTWYMVALLCRHRKK----TQHLQGTSLS-- ---PKTSPKQRATQTLLMLMSFFVL---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYNMQIFVVH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NCLRSV------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >51-m -----------------------------------------------MMRG--------- ------------------------------------------------------------ --------------------------------------------------AELPGVMNEI LFFSPQPLFSHMMNEN---------SRVHTHSNLR-------HIFFS------------- ---EIGIGIS------------GNSFLLLFHILKFIHG---H-----RSRLSDL-PIGLL -------SLIHLLMLLVMAFIAT-------------DIFISWRGWDDIICKFLVYLYRV- ---LRGLSLCTTSMLSVL-------QAIILSPRSS-CLA-KFKRKSL------HHISCAI LFL---------SVLYMLIGSQLLVSIIATPNLTTNDF-IYVTQSCSIL-PLSYVMQSMF STLLVIRDVFLI-----------SLMV-LSTWYMVALLCRHRKK----TQHLQGISLS-- ---PKTSPKQRATQTLLMLMSFFVL---MTIYDTIVSCSRTMF-----------LNDPT- ----------------------------------SYNMQIFVVH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------I ----V-NCLRSV------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >47.5-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLSVL-------QAIILSPRSC-CLA-KFKHKSS------HNISCAI IFL---------SVLYMSISSHLFISITATPNLTMNNF-LYVSQSCSLL-PLSYLMQSMY STLLVLREVFLI-----------GLMV-LSTSYMVALLCMHRKQ----AQNLQGTSLS-- ---LKTAPEQRATQTILMLMTFFVL---MSTFDSIVSSSRTMF-----------LDDPT- ----------------------------------CYSLYIFVMH---------------- ---I--YA-----------------------T-V--S---P--------------FV--- --------F-------------------------------MST-------EKH------L ----V-NFLRSMG--------------------------EWIIICES------------L LMVKILKKEG-------MCWHQTCQSWHAVYVLFQMLNM--------------------- ------------------------------------------------------------ ------------- >52.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKD---------NTLYCSVYIR-------NAFFS------------- ---EIGIGIS------------ANSCLLLFHTFMFIHG---H-----RARLTDL-PIGFV -------ALIHLVMLLLAAYITE-------------DFFMSSGGWDLITCKLVIFSHRF- ---FRSLSVCATCLLSVF-------QAIILCPQSS-HLA-KFKQNSP------HQLSYFF IFL---------SIFSTSISSQILIAAIATRNVTSVNL-IYITNSCSFL-PLSSSIQHTF STLLAFRNVFVI-----------GLMG-LSTCYMATLLCRHKTR----SQRLQNSKLS-- ---PKATPEQRALRTILMLMSFFLL---MSTFDSIISYSRTIL-----------KGNPL- ----------------------------------PYCVQILVAH---------------- ---S--YA-----------------------A-V--S---P--------------LL--- --------V-------------------------------LSN-------EKR------I ----T-NLLISMY--------------------------EKVVL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >52.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKD---------NTLYCSVYIR-------NAFFS------------- ---EIGIGIS------------ANSCLLLFHTFMFIHG---H-----RARLTDL-PIGFV -------ALIHLVMLLLAAYITE-------------DFFMSSGGWDLITCKLVIFSHRF- ---FRSLSVCATCLLSVF-------QAIILCPQSS-HLA-KFKQNSP------HQLSYFF IFL---------SIFSTSISSQILIAAIATRNVTSVNL-IYITNSCSFL-PLSSSIQHTF STLLAFRNVFVI-----------GLMG-LSTCYMATLLCRHKTR----SQRLQNSKLS-- ---PKATPEQRALRTILMLMSFFLL---MSTFDSIISYSRTIL-----------KGNPL- ----------------------------------PYCVQILVAH---------------- ---S--YA-----------------------A-V--S---P--------------LL--- --------V-------------------------------LSN-------EKR------I ----T-NLLISMY--------------------------EKVVL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >52-s -M---------------SIWVTPQFADHCVVCSCALGDGLYLLSRGPSMRRIHRDYS--- -------------------TFTC----LT------------------------------- --------------TKMIQFKTTFG---I---------------------AQLNGHKRQL LHASTQ----HNMNKD---------NKVYCSVYIR-------NAFFS------------- ---EIGIGIS------------ANSCLLLFHTFMFIRG---H-----RARLTDL-PIGFV -------ALIHLVMLLLAAYITR-------------DFFMSSGGWDDITCKLVIFLHRF- ---FRSLSVCATCLLSIY-------QAIILCPQSS-RLA-KFKHNSP------HQLSYFF IFL---------SIFYTSISSQILIAAIPTQNITFVNL-IYITNSCSFL-PLSSSMQHTF STLLAFRNVFVI-----------GLMG-LSTCYMATLLCRHKTR----SQRLQNSKLS-- ---PKATPEQRALRTILMLMSFFLL---MSTFDNIISYSRTIL-----------QGNPL- ----------------------------------PYCVQILVAH---------------- ---S--YA-----------------------A-V--S---P--------------LL--- --------V-------------------------------LSN-------EKR------I ----T-NLLISMY--------------------------EKVVL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >52.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKD---------HTLYCSVYIR-------NAFFS------------- ---EIGIGIS------------ANSCLLLFHTFMFIRG---H-----RPRLTDL-PIGFV -------ALIHLVMLLLAAYITE-------------DFFMSSGGWDDITCKLVIFLHRF- ---FRSLSVCATCLLSVF-------QAIILCPQSS-HLA-KLKQNSP------HQLSYFF IFL---------SIFYTSISSHILIAAIPTQNITFVNL-IYITNSCSFL-PLSSSMQHTF STLLAFRNVFVI-----------GLMG-LSTCYMATLLCRHKTR----SQRLQNSKLS-- ---PKATPEQRALRTILMLMSFFLL---MSTFDSIISYSRTIL-----------QGNPL- ----------------------------------PFCFQILVAH---------------- ---S--YA-----------------------A-V--S---P--------------LL--- --------V-------------------------------LSN-------EKR------I ----T-NLLISMY--------------------------EKIVL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >52.1-z ------------------------------------------------MRTIHRDYS--- -------------------TFIC----LT------------------------------- --------------TKMIQIKTTFG---I---------------------SQLNGHKRQL LRASTQ----HNMNKD---------HTLYCSVYIR-------NAFFS------------- ---EIGIGIS------------ANSCLLLFHTFMFIRG---H-----RPRLTDL-PIGFV -------ALIHLVMLLLAAYITR-------------DFFMSSGGWDDITCKLVIFLHRF- ---FRSLSVCATCLLSVF-------QAIILCPQSS-HLA-KFKQNSP------HQLSYFF IFL---------SIFYTSISSHILIAAIPTQNITFVNL-IYITNSCSFL-PLSSSMQHTF STLLAFRNVFVI-----------GLMG-LSTCYMATLLCRHKTR----SQRLQNSKLS-- ---PKATPEQRALRTILMLMSFFLL---MSTFDSIISYSRTIL-----------QGNPL- ----------------------------------PYCVQILVAH---------------- ---S--YA-----------------------A-V--S---P--------------LL--- --------V-------------------------------LSN-------EKH------I ----T-NLLISMY--------------------------EKVVLRFS------------V RVWK-------------------------IYIF--------------------------- ------------------------------------------------------------ ------------- >52.2-z ------------------------------------------------MRTIHRDYS--- -------------------TFIC----LT------------------------------- --------------TKMIQIKTTFG---I---------------------SQLNGHKRQL LRASTQ----HNMNKD---------HTLYCSVYIR-------NAFFS------------- ---EIGIGIS------------ANSCLLLFHTFMFIRG---H-----RPRLTDL-PIGFV -------ALIHLVMLLLAAYITR-------------DFFMSSGGWDDITCKLVIFLHRF- ---FRSLSVCATCLLSVF-------QAIILCPQSS-HLA-KFKQNSP------HQLSYFF IFL---------SIFYTSISSHILIAAIPTQNITFVNL-IYITNSCSFL-PLSSSMQHTF STLLAFRNVFVI-----------GLMG-LSTCYMATLLCRHKTR----SQRLQNSKLS-- ---PKATPEQRALRTILMLMSFFLL---MSTFDSIISYSRTIL-----------QGNPL- ----------------------------------PYCVQILVAH---------------- ---S--YA-----------------------A-V--S---P--------------LL--- --------V-------------------------------LSN-------EKR------I ----T-DLLISMY--------------------------EKVVL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >52.3-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MDMRNVFVI-----------GLMG-LSTCYMATLLCRHKTR----SQRLQNSKLS-- ---PKATPEQRALRTILMLMSFFLL---MSTFDSIISYSRTIL-----------QGNPL- ----------------------------------PFCFQILVAH---------------- ---S--YA-----------------------A-V--S---P--------------LL--- --------V-------------------------------LSN-------EKR------I ----T-NLLISMY--------------------------EKIVL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >52.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------M------------- ---EI----------------------------MMSRK---H-----------V-PI--- --------------------------------------------W--------------- ------------------------------------------------------------ ------------------------------------------------------------ -------NVFVI-----------GLMG-LSTCYMATLLCRHKTR----SQRLQNSKLS-- ---PKATPEQRALRTILMLMSFFLL---MSTFDSIISYSRTIL-----------QGNPL- ----------------------------------PFCFQILVAH---------------- ---S--YA-----------------------A-V--S---P--------------LL--- --------V-------------------------------LSN-------EKR------I ----T-NLLISMY--------------------------EKIVL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >52.4-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------M------------- ---EI----------------------------MMSRK---H-----------V-PI--- --------------------------------------------W--------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------HKTR----SQRLQNSKLS-- ---PKATPEQRALRTILMLMSFFLL---MSTFDSIISYSRTIL-----------QGNPL- ----------------------------------PFCFQILVAH---------------- ---S--YA-----------------------A-V--S---P--------------LL--- --------V-------------------------------LSN-------EKR------I ----T-NLLISMY--------------------------EKIVL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >V1ra8-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKD---------HTLYCSVYIR-------NAFFS------------- ---EIGIGIS------------ANSCLLLFHTFMFIRG---H-----RPRLTDL-PIGFV -------ALIHLVMLLLAAYITE-------------DFFMSSGGWDDITCKLVIFLHRF- ---FRSLSVCATCLLSVF-------QAIILCPQSS-HLA-KLKQNSP------HQLSYFF IFL---------SIFYTSISSQILIAAIPTQNITFVNL-IYITNSCSFL-PLSSSMQHTF STLLTFRNVFVI-----------GLMG-LSTCYMATLLCRHKTR----SQRLQNSKLS-- ---PKATPEQRALRTILMLMSFFLL---MSTFDSIISYSRTII-----------TGK--- ------------------------------------------------------------ ---S--TA-----------------------L-L--C---P--------------DS--- --------C-------------------------------RS------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >54-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKI---------NRLSHNTEIR-------NAIYS------------- ---GVGIGIS------------GNSFLLLFHILKYIRG---Q-----RSRPIDL-PIGLL -------SLIHLLMLIVMSLVAT-------------DIFMPWGRWGDTTCKCVISLYRL- ---CRSLSLCATSLLSIL-------QAVTLSPRNS-CLE-KLKHKSP------HYMLGCL LFL---------SVFYTFISSPLATYITAKSNLTSPSF-TYITTSCSLA-PMSYSFHLTV FILLTSRDVIFV-----------GLML-LSSGYMVTFLGRHKKQ----SQFLHSTSLS-- ---LKPSAEKRAMRTILCLMSFFVL---MYTLDSIVSYIRSI------------DDGQI- ----------------------------------IYCVHIFTAH---------------- ---G--YA-----------------------T-V--S---P--------------FL--- --------I-------------------------------LST-------EKY------I ----I-SIFRSTF--------------------------GRMVTI--------------- -------------------------------ILLRNR----------------------- ------------------------------------------------------------ ------------- >54-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKM---------NRLSHNTEIR-------NAIYS------------- ---GVGIGIS------------GNSFLLLFHIFKYIRG---Q-----RSRPIDL-PIGLL -------SLIHLVMLIVMSLVAT-------------DIFMPWERWGDTTCKCVISLYRF- ---CRSLSLCATSLLSIL-------QAVTLSPRNS-CLE-KFKRKSP------HYMLGCL LFL---------SVFYTFISSPLATYITAKSNLTSPSF-TYITTSCSLA-PMSYSFHLTV FILLTSRDVIFV-----------GLML-LSSGYMVTFLGRHKKQ----SQFLHITSFS-- ---LKPTAEKRAMRTILCLMSFFVL---MYTLDSIVSYIRSI------------DDGQI- ----------------------------------FYCVHIFTAH---------------- ---G--YA-----------------------T-V--S---P--------------FL--- --------I-------------------------------LST-------EKY------I ----I-NIFRSTF--------------------------GRMVTI--------------- -------------------------------ILLRNR----------------------- ------------------------------------------------------------ ------------- >54-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNKM---------NRLSHNTEIR-------NAIYS------------- ---GVGIGIS------------GNSFLLLFHIFKYIRG---Q-----RSRHIDL-PIGLL -------SLIHLVMLIAMSLVAT-------------DIFMPWGRWGDTTCKCVISLYRF- ---CRSLSLCATSLLSIL-------QAVTLNPRNS-CLE-KFKRKSP------HYMLGCL LFL---------SVFYTFISSPLATYITAKSNLTSPSF-TYITTSCSLA-PMSYSFHLTV FILLTSRDVIFV-----------GLML-LSSGYMVTFLGRHKKQ----SQFLHITSFS-- ---LKPSAEKRAMRTILCLMSFFVL---MYTLDSIVSYIRSI------------DDGQI- ----------------------------------FYCVHIFTAH---------------- ---G--YA-----------------------T-V--S---P--------------FL--- --------I-------------------------------LST-------EKY------I ----I-NIFRSTF--------------------------GRMVTI--------------- -------------------------------ILLRNR----------------------- ------------------------------------------------------------ ------------- >1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNRN---------DPVYNINGIR-------NAFFS------------- ---EIAFGVS------------ANTILLLSHVVTFFQE---L-----RHKPINI-TIGVL -------ALSHIVMLLAMAAMAT-------------DILGSQGFWDDFTCKSVISLYRL- ---MRGVSICATCHLSIL-------QVILLSPRSS-CLA-KVKPNSL------WHNLCCF LFL---------WAFHMSING-FANSIVVAHNVTSHIL-ILVTKSCSLW-VVSDIMRHLL SILAVFRDTSLV-----------GLMV-LSSVYMVTVLCRHKRQ----CQYLHNTSIS-- ---RKASPEQRAIRNILLLVSFFLV---TYCLDSIASSWRVMW-----------NNDST- ----------------------------------HRCVQMFVSN---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------F-------------------------------IST-------EQR------I ----I-NFLKTTQ--------------------------GQQ------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNRN---------DPVYNINGIR-------NAFFS------------- ---EIVFGVS------------ANTILLLSHVVTFFQE---L------------------ ---------------------------------------------------------RL- ---MRGVSICATCHLSVL-------QVILLSPRSS-CLA-KVKPNSL------WHNLCCF LSL---------WAFHMSINV-FSNSIVATHNVTSHIL-ILVTKSCSLW-VVSDIMRHLL SILAAFRDASLV-----------GLMV-LSSIYMVTVLCRHKRQ----CQYLHNTSIS-- ---RKASPEQRAIRNILLLVSFFLV---TYCLDSIASSWRVMW-----------NNDPT- ----------------------------------HRCVQMFVSS---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------F-------------------------------IST-------EQR------I ----I-NCLKTTQ--------------------------GQQ------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNRN---------DRVYNISGIR-------NAFFS------------- ---EIVFGVS------------ANTILLLSHVVTFFQE---L-----RHKPINI-TIGVL -------ALSHIVMLLAMAAMAT-------------DILGSQEFWDDYTCKSVISLYRL- ---MRGVSICATCHLSVL-------QVILLSPRSS-CLA-KVKPNSL------WHNLCCF LSL---------WAFHMSINV-FSNSIVATHNVTSHIL-ILVTKSCSLW-VVSDIMRHLL SILAAFRDASLV-----------GLMV-LSSIYMVTVLCRHKRQ----CQYLHNTSIS-- ---RKASPEQRAIRNILLLVSFFLV---TYCLDSIASSWRVMW-----------NNDPT- ----------------------------------HRCVQMFVSS---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------F-------------------------------IST-------EQR------I ----I-NCLKTTQ--------------------------GQQ------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNRN---------DPVYNISGIR-------NAFFS------------- ---EIVFGVS------------ANTILLLSHVVTFFQE---L-----RHKPINI-TIGVL -------ALSHIVMLLAMAAMAT-------------DILGSQEFWDDYTCKSVISLYRL- ---MRGVSICATCHLSVL-------QVILLSPRSS-CLA-KVKPNSL------WHNLCCF LSL---------WAFHMSINV-FSNSIVATHNVTSHIL-ILVTKSCSLW-VVSDIMRHLL SILAAFRDASLV-----------GLMV-LSSIYMVTVLCRHKRQ----CQYLHNTSIS-- ---RKASPEQRAIRNILLLVSFFLV---TYCLDSIASSWRVMW-----------NNDPT- ----------------------------------HRCVQMFVSS---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------F-------------------------------IST-------EQR------I ----I-NCLKTTQ--------------------------GQQ------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNRN---------DPVYNINGIR-------NAFFS------------- ---EIVFGVS------------ANTILLLSHVVTFFQE---L-----RHKPINI-TIGVL -------ALSHIVMLLAMAAMAT-------------DILGSQGFWDDFTCKSVISLYRL- ---MRGVSICATCHLSVL-------QVILLSPRSS-CLA-KVKPNSL------WHNLCCF LSL---------WAFHMSINV-FSNSIVAAHNVTSHIL-ILVTKSCSLW-VVSDTMRHLL SILAAFRDASLV-----------GLMV-LSSIYMVTVLCRHKRQ----CQYLHNTSIS-- ---RKASPEQRAVRNILLLVSFFLV---TYCLDSIASSWRVMW-----------NNDPT- ----------------------------------HRCVQMFVSS---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------F-------------------------------IST-------EQR------M ----I-NCLKNTQ--------------------------GQQ------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MNRN---------DPVYNNNGIR-------NAFFS------------- ---EIAFGVS------------ANTILLLSHAVTFFQE---L-----RHKPINI-TIGVL -------ALSHIVMLLAMAAMAT-------------DILGSQGFWDDFTCKSVISLYRL- ---MRSVSICATCHLSIL-------QVILLSPRSS-CLA-KVKPNSL------QHNLCCF LSL---------WAFHMSING-FLNSIVAAHNMTSHIL-ILVTKSCSLC-VVSGIMRHLL SILAVFRDASLV-----------GLMV-LSSVYMVTVLCRHKRQ----CQYLHNTSIS-- ---RTASPEQKAIRNILLLVSFFLV---MYCLDSIASSWRVMW-----------NNDPT- ----------------------------------HRCVQMFVSN---------------- ---G--YA-----------------------T-F--S---P--------------LV--- --------F-------------------------------IST-------EQR------I ----I-NFLKTTQ--------------------------GQQ------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal91.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAD-GKSLETTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHI -------AGTNALTLFFTIFTNNM------------MAFARKTPPTDLKCKLEFFSSMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNR--GILILRANVS------NLVSYSC YSC---------WFFSVLTNIHIPINFTGPQITDNNTD-SKSNLFCST-----SGFTVGI VFLQFSHDATFM-----------SIMV-WTSV---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal91.2-c ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MS-Y LIITPVSVKALPMCTL-DKSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHI -------AGTNALTLFFTIFTNNM------------MAFARKTPPTDLKCKLEFFSSMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNR--GILILRANVS------NLVSYSC YSC---------WFFSVLTNIHIPINFTGPQITDNNTD-SKSNLFCST-----SGFTVGI VFLQFSHDATFM-----------SIMV-WTSV---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >V1rd19.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSTH-DTSLRTTEEVAF---QI---------LLLC------------- ---QFGVGTF------------ANVFLFVYNFSPISTG---S-----KQRPRQV-ILRHM -------AVANALTLFLTIFPNNM------------MTFAPIIPQTDLKCKLEFFTRLI- ---ARSTNLCSTCVLSIH-------QFVTLVPVNS--GKGILRASVT------NMASYSC YSC---------WFLSVLNNIYIPIKVTGPQITDNNNN-SKSKLFCST-----SEFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHCQR----MQHIFTFNQD-- ---PRGQAETTATHTILMLVVTFVG---FYLLSLICIIFYTYFIY--------------- -SHHF-----------LRH------------------CNDILVS---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--GPCSV -------FFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >V1rd19-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSTH-DTSLKTTEEVAF---QI---------LLLC------------- ---QFGVGTF------------ANVFLFVYNFSPISTG---S-----KQRPRQV-ILRHM -------AVANALTLFLTIFPNNM------------MTFAPIIPQTDLKCKLEFFTRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNS--GKGILRASVT------NMASYSC YSC---------WFFSVLNNIYIPIKVTGPQLTDNNNN-SKSKLFCST-----SEFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHCQR----MQYIFTLNQD-- ---PRGQAETTATHTILMLVVTFVG---FYLLSLICIIFYTYFIY--------------- -SHHF-----------LRH------------------CNDILVS---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--GPCSV -------FFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >V1rd19-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSTH-DTSLKTTEEVAF---QI---------LLLC------------- ---QFGVGTF------------ANVFLFVYNFSPISTG---S-----KQRPRQV-ILRHM -------AVANALTLFLTIFPNNM------------MTFAPIIPQTDLKCKLEFFTRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNS--GKGILRASVT------NMASYSC YSC---------WFFSVLNNIYIPIKVTGPQLTDNNNN-SKSNLFCST-----SEFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHCQR----MQYIFTLNQD-- ---PRGQAETTATHTILMLVVTFVG---FYLLSLICIIFYTYFIY--------------- -SHHF-----------LRH------------------CNDILVS---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--GPCSV -------FFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >V1rd19-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSTH-DTSLKTTEEVAF---QI---------ILLC------------- ---QFGVGTF------------ANVFLFVYNFSPISTG---S-----KQRPRQV-ILRHM -------AVANALTLFLTIFPNNM------------MTFAPIIPQTDLKCKLEFFTRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNS--GKGILRASVT------NMASYSC YSC---------WFFSVLNNIYIPIKVTGPQLTDNNND-SKSKLFCST-----SEFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHCQR----MQYIFTLNQD-- ---PRGQAETTATHTILMLVITFVG---FYLLSLICIIFYTYFIY--------------- -SHHF-----------LRH------------------CNDILVS---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--GPCSV -------FFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >V1rd19-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSTH-DTSLKTTEEVAF---QI---------ILLC------------- ---QFGVGTF------------ANVFLFVYNFSPISTG---S-----KQRPRQV-ILRHM -------AVANALTLFLTIFPNNM------------MTFAPIIPQTDLKCKLEFFTRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNS--GKGILRASVT------NMASYSC YSC---------WFFSVLNNIYIPIKVTGPQLTDNNNN-SKSKLFCST-----SDFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHCQR----MQYIFTLNQD-- ---PRGQAETTATHTILMLVVTFVG---FYLLSLICIIFYTYFIY--------------- -SHHS-----------LRH------------------CNDILVS---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------TFR-------DPK--GPCSV -------FFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >V1rd19-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSTH-DISLK---EVTF---QI---------LLLC------------- ---QFGVGTF------------ANVFLFAYNFSPILTG---S-----KQRPRQV-ILRHM -------AVANALTLFLTIFPNNM------------MTFAPIIPQTDLKCKLEFFTRLV- ---ARSTNLCSTCVLSIH-------QFVTLDPVNS--GKGILRASVT------NMASYSC YSC---------WFFSILNNIYIPIKVTGPKLTDNNND-SKSNLFCST-----SEFSVGI VFLWFAHDATFM-----------SIMI-WTSVSMVLLLHRHCQR----MQHIFTPNQN-- ---PGGQAETTATHTIVMLVVTFVG---FYLLSLICIIFYTYFIY--------------- -SHRF-----------LRH------------------CNDILVS---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--GPCSV -------HFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >V1rd19.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSTH-DTSLRTTEEVAF---QI---------LLLC------------- ---QFGVGTF------------ANVFLFVYNFSPISTG---S-----KQRPRQV-ILRHM -------AVANALTLFLTIFPNNM------------MTFAPIIPQTDLKCKLEFFTRLI- ---ARSTNLCSTCVLSIH-------QFVTLVPVNS--GKGILRASVT------NMASYSC YSC---------WFFSVLNNIHIPIKVTGPQITDNNND-SKSKLFCST-----SGFSVGI IFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHHQR----MQHILTPNQD-- ---PRGQAETRATRTILMLVVTFVS---FYLLNCICVIFQTFFID--------------- -SRLF-----------VRH------------------VGEVFIA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--APCSV -------RFRC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >180.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-DKSLKTTEEVAL---QI---------LLLC------------- ---HFGVGTV------------ANVCLFVHNFYPVLTG---S-----QQRPRQV-ILSHM -------AVTNALTLLFTIFPNNM------------MAFAPRNPLSDLKCKLEFFTRLV- ---ARSINLCSTCVLSIH-------QFVTLVPVNR--GKLILRASVP------NLARYSC YSC---------WLFSVLNNIYIPIKLTGPQITDNNND-SKSKLFCST-----SGFSVGI IFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHHQR----MQHILTPNQD-- ---PRGQAETKATHTILMLVITFVS---FYLLNFICTIFHMFFVD--------------- -SYLF-----------VRH------------------CSEVFVA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >180.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-EKFLKNTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QKSPRQV-ILSHI -------AVANVLILFITTFQNNM------------MAFAPKNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNR--GKLILRASVP------NLARYSC YSC---------WLFSVLNNIYIPIKLTGPQITDNNND-SKSKLFCST-----SGFSVGI IFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHHQR----MQHILTPNQD-- ---PRGQAETKATHTILMLVITFVS---FYLLNFICTIFHMFFVD--------------- -SYLF-----------VRH------------------CSEVFVA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >180.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-EKFLKNTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QKRPRQV-ILSHM -------AVANVLILFISTFQNNM------------MAFASKNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNR--GKLILRASVP------NLASYFC YSC---------WFFSVLNNIYIPIKLTGPQITDNNND-SKSKLFCST-----SGFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----KQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVG---FHLLNFICTIFHMFL----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >180.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-EKFLKNTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QKRPRQV-ILSHM -------AVANVLILFISTFQNNM------------MAFASKNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNR--GKLILRASVP------NLASYFC YSC---------WFFSVLNNIYIPIKLTGPQITDNNND-SKSKLFCST-----SGFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----KQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVG---FHLLNFICTIFHMFFVD--------------- -SYLF-----------VRH------------------CSEVFVA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >180.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-EKFLKNTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQRPRQV-ILSHM -------AVANVLILFISTFQNNM------------MAFASKNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNR--GKLILRASVP------NLASYFC YSC---------WFFSVLNNIYIPIKLTGPQITDNNND-SKSKLFCST-----SGFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----KQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVG---FHLLNFICTIFHMFFVD--------------- -SYLF-----------VRH------------------CSEVFVA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >180-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-EKFLKNTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQRPRQV-ILSHM -------AVANILILFITTFQNNM------------MAFASKNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNR--GKLILRASVP------NLASYSC YSC---------WFFSVLNNIYIPIKLTGPQITDNNND-SKSKLFCST-----SGFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLRRHQQQ----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FHLLNFICTIFHMFFVD--------------- -SYLF-----------VRH------------------CSEVFVA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCSM -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >178.2-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-EKFLKNTEEVAL---QI---------LLFC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QKRPRQV-ILSHM -------AVANILILFITTFQNNM------------MAFASRNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNR--GKAILRASVP------NLTSYSC YSC---------WFFSVLSNIYIAIKVTGPQITDNNTD-SKSKLFCFT-----SGFSVGI FFLRIFHDGTFM-----------SIMV-WTSVSMVLLLH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >183.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQRPRQV-LLSHM -------AVTNALTLFLTMFPNNM------------MAFAPRNPLTDLKCKLEFFTRLV- ---ARSINLCSTCVLSVH-------QFVTLVPVNK--GKLILRASVT------NMASYSC YSC---------WFFSVLNNIHIPIKVTGPQITDNNND-SKSKLFCST-----SGFSVGI VFLQFAHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQN-- ---PRGQAESRATHTILMLVVTFVS---FYLLNFICIIFQTFFID--------------- -SRLF-----------VRH------------------VGEVFVA---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--GPCSV -------LFSF------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >183.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQRPRQV-LLSHM -------AVTNALTLFLTMFPNNM------------MAFAPRNPLTDLKCKLEFFTRLV- ---ARSINLCSTCVLSVH-------QFVTLVPVNK--GKLILRASVT------NMASYSC YSC---------WFFSVLNNIHIPIKVTGPQITDNNND-SKSKLFCST-----SGFSVGI VFLQFAHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQN-- ---PRGQAETRATHTILMLVVTFVS---FYLLNFICIIFQTFFID--------------- -SRLF-----------VRH------------------VGEVFVA---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--GPCSV -------LFSF------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >183-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-SKSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVCLFVHNFSPVLTG---S-----KQRPRQV-LLSHM -------AVTNALTLFLTIFPNNM------------MAFAPRNPLTDLKCKLEFFTRLV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNK--GKLILRASVT------NMASYSC YSC---------WFFSVLNNIHIPIKVTGPQITDNNND-SKSKLFCST-----SGFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLRRHRQR----MQHILTPNQD-- ---ARGQAESRATNTILMLVVTFVS---FYLLNFICIIFQTFFID--------------- -SRLF-----------VRH------------------VGEVFVA---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >183-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------M -------AVTNALTLFLTIFPNNM------------MAFAPRNPLTDLKCKLEFFTRLV- ---ARSINLCSTCVLSVH-------QFVTLVPVNK--GKLILRASVT------NMASYSC YSC---------WFFSVLNNIYIPIKVTGPQLTDNNND-SKSKLFCST-----SEFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNFICIIFQTFFID--------------- -SRLF-----------VRH------------------VGEVFVA---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >183-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQRPRQV-LLSHM -------AVTNALTLFLTIFPNNM------------MAFSPRNPLTELKCKLEFFIRLV- ---ARSINLCSTCVLSVH-------QFVTLVPVNK--GKLILRASVT------NMASYSC YSC---------WFFSVLSNIYVPIKVTGPQITDNNTD-SKSKFFCST-----SGFTVRI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---PRGQAESRATHTILMLVVTFVS---FYLLNFICIIFQTFFID--------------- -SRLF-----------VRH------------------VGEVFVA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal91-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQRPRQV-LLSHM -------AVTNALTLFLTIFPNNM------------MAFSPRNPLTELKCKLEFFIRLV- ---ARSINLCSTCVLSVH-------QFVTLVPVNK--GKLILRASVT------NMASYSC YSC---------WFFSVLSNIYVPIKVTGPQITDNNTD-SKSNLFCST-----SGFTVRI VFLRFAHDVTFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQY-- ---RRGQAETRATHTILMLVVTFVS---FYLLNFTCIIFHTLLMH--------------- -SHLF-----------IRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >183-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MASYTC YSC---------WFFSVLNNIYIPIKVTGPQITDNNND-SKSKLFCST-----SGFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMLLLLYRHHQR----MQHFLTPNQD-- ---PRCQAETRATHTILMLVVTFVS---FYLLHFICIIFQTFFID--------------- -SRLF-----------VRH------------------VSEVFNA---------------- ---S--FP-----------------------T-I--S---P--------------LV--- --------L-------------------------------IFR-------DPK--DPCSV -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >181-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-TKSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFLPVLTG---S-----KQRPRQV-ILSHI -------TVANALILFITTFPNNM------------MAFAPRSPQTDLKCKLEFFIRMV- ---ARSSSLCSTCVLSIH-------QFLTLVPVNR--GKLILRASVP------NLASYSC YSC---------WFFSILNNIYIPMKVTGPQITDNIND-SKSKLFCST-----SGFNVGI VLLRFAHDATFM-----------SIMV-WTSVSMVL------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >181-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFFPILTG---S-----KQRPRQV-ILSHI -------AVANALTLFITTFPNNM------------MAFAPRSPQNDLKCKLEFFIRMV- ---ARSTGLCSTCVLSIH-------QFLILVPVNR--GKLILRASVP------NLVSYSC YSC---------WFFSVLNNIYIPIKVTGPQITDSKND-SKSKLFCST-----SGFNVGI VFLQFAHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQN-- ---PRGQAESRATHTILMLVVTFVS---FYLLHFICIIFYTFFIY--------------- -SHQF-----------LRH------------------CSEVLVV---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------EPK--GPCSV -------FFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >181-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-DKSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTF------------ANVFLFVHNFFPILTG---S-----KQRPRQV-ILSHI -------AVANALTLFITTFPNNM-------------AFAPRSPQNDLKCKLEFFIRMV- ---ARSTGLCSTCVLSIH-------QFLTLVPVNR--GKLILRTSVP------NLVSYSC YSC---------WFFSVLNNIYIPIKVTGPQITDSKND-SKSKLFCST-----SGFNVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQYIFTLNQD-- ---HRSQAETKATHTILMLVVTFVS---FYLLHFICIIFYTFFIY--------------- -SHQF-----------LRH------------------CSEVLVV---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--GPCSV -------FFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >181-x ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------MIAVS-C LIITLGLYKALSMSAH-GKSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFFPILTG---S-----TQRPRQV-ILSHI -------AVANALTLFITTFPNNM------------MAFAPRSPQNDLKCKLEFFIRMV- ---ARSTGLCSTCVLSIH-------QFLTLVPVNR--GKLILRASVP------NLVSYSC YSC---------WFFSVLNNIYIPIKVTGPQLTDNNND-SKSKLFCST-----SEFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHHQR----MQYIFTLNQD-- ---HRSQAETKATHTILMLVVTFVS---FYLLHFICIIFYTFFIY--------------- -SHQF-----------LRH------------------CSEVLVV---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--GPCSV -------FFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal91-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------MAFAPRNPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNK--GKLILRASVT------NMASYSC YSC---------WFFSVLNNIYIPIKVTGPQLTDNNND-SKSKLFCST-----SEFSVGI VFLRFAHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQY-- ---RRGQAETRATHTILMLVVTFVS---FYLLNFTCIIFHTLLMH--------------- -SHLF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal111.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPNELKCKLESFSRLV- ---ARSTNLCSTCALSIH-------QFVTLFPVSRGKVKLILRASVQ------NLASYSC YSC---------WFFSVLSNIHIPIRVTGPQITDNNTD-SKSNLFCST-----SGFIVGI V-LQFAHDATFM-----------SIMV-WTSV---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal111.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVTNALTLFLTVFPNNM------------MAFAPKTPPNELKCKLESFSRLV- ---ARSTNLCSTCALSIH-------QFVTLFPVSRGKVKLILRASVQ------NLASYSC YSC---------WFFSVLSNIHIPIRVTGPQITDNNTD-SKSNLFCST-----SGFIVGI V-LQFAHDATFM-----------SIMV-WTSVSMILLLHRHRQR----MQHILTPNQN-- ---PRGQAESRATHTILMLVVTFVS---FYLLNSICIIFHTFFIH--------------- -SRLF-----------IRL------------------VSEVLTA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >111-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVH-DKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---Y-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPNELKCKLESFSRLV- ---ARSTNLCSTCVLSIH-------QFVTLFPLSRGKGKLILRASVQ------NLASYSC YSC---------WFFSVLSNIHIPIRVTGPQITDNNTD-SKSNLFCST-----SGFIVGI V-LQFAHDATFM-----------SIMI-WTSVSMILLLHRHCQR----MQDILTPNQN-- ---PRGQAETRATRTILMLVVTFVS---FYLLNCICIIFHAFFIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >166-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVH-DKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---Y-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPNELKCKLESFSRLV- ---ARSTNLCSTCVLSIH-------QFVTLFPLSRGKGKLILRASVQ------NLASYSC YSC---------WFFSVLSNIHIPIRVTGPQITDNNTD-SKSNLFCST-----SGFIVGI V-LQFAHDATFM-----------SIMI-WTSVSMILLLHRHCQR----MQDILTPNQN-- ---PRGQAETRATRTILMLVVTFVS---FYLLNCICIIFHAFFIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >138-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVH-DKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---Y-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPNELKCKLESFSRLV- ---ARSTNLCSTCVLSIH-------QFVTLFPLSRGKGKLILRASVQ------NLASYSC YSC---------WFFSVLSNIHIPIRVTGPQITDNNTD-SKSNLFCST-----SGFIVGI V-LQFAHDATFM-----------SIMI-WTSVSMILLLHRHCQR----MQDILTPNQN-- ---PRGQAETRATRTILMLVVTFVS---FYLLNCICIIFHAFFIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >131-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVH-DKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---Y-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPNELKCKLESFSRLV- ---ARSTNLCSTCVLSIH-------QFVTLFPLSRGKGKLILRASVQ------NLASYSC YSC---------WFFSVLSNIHIPIRVTGPQITDNNTD-SKSNLFCST-----SGFIVGI V-LQFAHDATFM-----------SIMI-WTSVSMILLLHRHCQR----MQDILTPNQN-- ---PRGQAETRATRTILMLVVTFVS---FYLLNCICIIFHAFFIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >118-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVH-DKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPNELKCKLESFSRLV- ---ARSTNLCSTCVLSVH-------QFVTLFPVSRGKGKLILRASVQ------NLASYSC YSC---------WFFSVLSNIHIPIRVTGPQITDNNTD-SKSNLFCST-----SGFIVGI V-LQFAHDATFM-----------SIMI-WTSVSMILLLHRHCQR----MQDILTPNQN-- ---PRGQAETRATRTILMLVVTFVS---FYLLNCICIIFHAFFIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal111.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPNELKCKLESFSHMV- ---TRSTNLCSTCVLSVH-------QFVTLFPVSKGKGKLILRASVQ------NLASYSS YSC---------WFFSVLSNIHIPIRVTGPQITDNNTD-SKSNLFCST-----SGFIVGI V-LQFAHDATFM-----------SIMV-WTSVSMILLLRRHRQR----MQHILTPNQN-- ---PRGQAESRATRTILMLVVTFVS---FYLLNCICIIFHAFFIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >137-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPNELKCKLDFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >107-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPNELKCKLDFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >130-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPNELKCKLDFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >155-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPNELKCKLDFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >165-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPNELKCKLDFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >95-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFFHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPNELKCKLEFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >143-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFFHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPNELKCKLEFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >116-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFFHNFSPVLTG---S-----KQRPRQV-FLSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPNELKCKLEFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >152-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFASKTPPNELKCKLEFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFGST-----SGFIVGM VFLQFSHDATFM-----------TIMV-WTSVSMVLLLHRHRQQ----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVR---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >104-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFASKTPPNELKCKLEFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFGST-----SGFIVGM VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQQ----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVR---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >135-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVMTG---S-----KKRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPTELKCKLEFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLKFSHDATFM-----------TIMV-WTSVSMVLLLHRHHQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------N-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >163-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVMTG---S-----KKRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPTELKCKLEFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLKFSHDATFM-----------TIMV-WTSVSMVLLLHRHHQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------N-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >128-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KKRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPTELKCKLEFFSHMV- ---ARSKNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFSHDATFM-----------TIMV-WTSVSMVLLLHRHHQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLGA---------------- ---V--FP-----------------------N-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPFSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >125-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSMKTTEEVAL---QI---------ILLC------------- ---QFGIGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFARKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRASVP------NFANYSC YSC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >100-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGIGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRASVP------NFANYSC YSC---------WFFSVLSNIHIPIKVTVPQIIDNNTD-SKSNLFCST-----SGFIVGI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >148-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGIGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRASVP------NFANYSC YSC---------WFFSVLSNIHIPIKVTVPQIIDNNTD-SKSNLFCST-----SGFIVGI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >112-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRASVP------NFANYSC YSC---------WFFSVLSNIHIPIKVTGPQIIDNNTY-DKSNLFCST-----SGFIVGI VFLQISHDATFM-----------SIMV-WTSVSMVLLL--------------LTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPN--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >139.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFFSVLSNIHIPIKVTGPQIIDNNTY-DKSNLFCST-----SGFIVGI VFLQISHDATFM-----------SIMV-WTSVSMVLLL--------------LTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPN--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >132-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRASVP------NLWNYSC YSC---------WFFSVLSNIHIPIKVTGPQIIDNNTY-DKSNLFCST-----SGFIVGI VFLQISHDATFM-----------SIMV-WTSVSMVLLL--------------LTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPN--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >157-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QI---------LLLC------------- ---HFEVGTV------------ANVFLFVHNFSPVLTG---Y-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRASVP------NFANYSC YSC---------WFFSVLSNIHIPIKVTGPQIIDNNTY-DKSNLFCST-----SGFIVGI VFLQISHDATFM-----------SIMV-WTSVSMVLLL--------------LTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPN--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >91-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFVVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFGPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRVSVP------NFANYSC YSC---------WFFSVLSNIHIPIKVTGPQIIDNNTD-SKSNLFCST-----SGFIVGI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHHQR----MQHILTPNQD-- ---PRGQAGSRATHTILMLVITFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-V--C---P--------------LV--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >100/148.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTM------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTVFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRASVP------NFANYSC YSC---------WFFSVLSNIHIPIKVTVPQIIDNNTD-SKSNLFCST-----SGFSVGI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >100/148.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVCLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTVFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRASVP------NFANYSC YSC---------WFFSVLSNIHIPIKVTVPQIIDNNTD-SKSNLFCST-----SGFSVGI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >124-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTL------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTTFPNNM------------MAFGPKTPPTELKCKLEFFSHIV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLILRVSVP------NFANYSC YSC---------WFFSVLSNIHIPIKVTGPQIIDNNTD-SKSNLFCST-----SGFIVGI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQN-- ---PRGQAETRENRTILMLVVTFVS---FYLLNFICIIFHAFSIH--------------- -SLLF-----------MRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---T--------------LV--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >123-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILIHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASIP------NLWNYSC YNC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGM VFLQFAYDATFM-----------IIMV-WTSVSMVLLLHRHRQR----MQHILTPNQN-- ---PRGQAETRATRTILMLVVTFVS---FYLLNFICIIFHAFSIH--------------- -SHLF-----------IRL------------------VSVVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------IFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >160-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSLKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILIHM -------AVANALTLFLTIFPNNM------------SAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSIH-------QFVTLVPVNRGKGKLILRASIP------NLWNYSC YNC---------WFYSVLSNIHIPIKVTGPQITDNNTD-SKSKLFCST-----SGFIVGM VFLQFAYDATFM-----------IIMV-WTSVSMVLLLHRHRQR----MQHILTPNQN-- ---PRGQAETRATRTILMLVVTFVS---FYLLNFICIIFHAFSIH--------------- -SHLF-----------IRL------------------VSVVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >122-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSDH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTL------------ANVFLFVHNFYPVLTG---S-----KQRPRQV-ILSHM -------SVANALTLFLTIFPNNM------------IAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSIY-------QFVTLVLVNR--GKLILKASVP------NFVSYSC YSC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGI VFLQFAYDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQN-- ---PRGQAETRATRTILMLVFTFVS---FYLLNFICIIFHTLLMH--------------- -SHFF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--S---P--------------FL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >159-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSDH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTL------------ANVFLFVHNFYPVLTG---S-----KQRPRQV-ILSHM -------SVANALTLFLTIFPNNM------------IAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSIH-------QFVTLVLVNR--GKLILRASVP------NLVSYSC YGC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGI VFLQFAYDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQN-- ---TRGQAESKATRTILMLVFTFVS---FYLLNFICIIFHTLLMH--------------- -SHFF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--S---P--------------FL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >103-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSDH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTL------------ANVFLFVHNFYPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------IAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSIY-------QFVTLVLVNR--GKLILRASVP------NFVSYSC YSC---------WFFSVLSNIHISIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGI VSLQFAYDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQY-- ---RRGQAETRATRTILMLVVTFVS---FYLLNFICIIFHTLLMH--------------- -SHLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------GPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >151-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSDH-GKSVKTTEEVAL---QI---------LLLC------------- ---QFGVGTL------------ANVFLFVHNFYPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------IAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSIY-------QFVTLVLVNR--GKLILRASVP------NFVSYSC YSC---------WFFSVLSNIHISIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGI VSLQFAYDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQY-- ---RRGQAETRATRTILMLVVTFVS---FYLLNFICIIFHTLLMH--------------- -SHLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------GPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >127-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSDH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTL------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AMANALTLFLTIFPNNM------------IAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSIH-------QFVTLVLVNR--GKLILRASVP------NFVSYSC YSC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGI VFLQFAYDATFM-----------SIMV-WTSVSMILLLHRHRQR----MQHILTPNQN-- ---PRGQAETRATRTILMLVVTFVS---FYLLNFICIIFHTLLMH--------------- -SHLF-----------IRL------------------VSEVLTA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >94-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSDH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTL------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AMANALTLFLTIFPNNM------------IAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSIH-------QFVTLVLVNR--GKLILRASVP------KFVSYSC YSC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGI VFLQFAYDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVIFVS---FYLLNFICIIFHTLLMH--------------- -SHLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >142-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSDH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTL------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AMANALTLFLTIFPNNM------------IAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSIH-------QFVTLVLVNR--GKLILRASVP------KFVSYSC YSC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGI VFLQFAYDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNFICIIFHTLLMH--------------- -SHLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >120-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSDH-AKSLKSTEEVAL---QL---------LLLC------------- ---QFGVGTL------------ANVFLFVHNFYPVLTG---S-----KQRPRKV-ILSHM -------AVANALTIFLTIFPNNM------------IAFAPKTPPTELKCKLEFFSHMV- ---ARNTNLCSTCVLSIH-------HFVTLVLVNR--GKLILRASVP------NFVSYSC YSC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIGGI VFLQFSYDATFM-----------SIMV-WTSVSMILLLHRHRQR----MQHILTPNQY-- ---RRGQAESRATHTILMLVVTFVS---FYLLNFICIIFHTLLMH--------------- -SHLF-----------TRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------ILNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >115-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSDH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTL------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AMANALTLFLTIFPNNM------------IAFAPKTPPTELKCKLEFFSHMV- ---ARSTNLCSTCVLSIH-------QFVTLVLVNR--GKLILRASVP------KFVSYSC YSC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSNLFCST-----SGFIVGI VFLQFAYDATFM-----------SIMV-WTSVSIILLLHRHRQR----MQHILTPNQN-- ---PRGQAETRATRTILMLVVTFVS---FYLLNCICIIFHAFYIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--CLHNG--------------VL--- --------L-------------------------------SY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >113/117/129.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-CNSLKTTEEVAL---QL---------LLIC------------- ---QFGIGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSTCVLSVH-------QYVTLVPVNRGKGKLVLRASFT------NMASYSS YSC---------WFFSVLSNIHFPIKVSGPQITDNNTD-SKRKLFCST-----SGFSVGF VFLQFAYDTTFM-----------SIMV-WTSVSMVLLLRRHRQR----MQHILTPNQN-- ---PRGQAESRATHTILMLVVTFVS---FYLLNFICIMLHALFTH--------------- -SHFF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >113/117/129.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-CNSLKTTEEVAL---QL---------LLIC------------- ---QFGIGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSTCVLSVH-------QYVTLVPVNRGKGKLVLRASFT------NMASYSS YSC---------WFFSVLSNIHFPIKVSGPQITDNNTD-SKRKLFCST-----SGFSVGF VFLQFAYDTTFM-----------SIMV-WTSVSMVLLLRRHRQR----MQHILTPNQN-- ---PRGQAESRATHTILMLVVTFVS---FYLLNFICIMLHALFTH--------------- -SHFF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >113/117/129.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-CNSLKTTEEVAL---QL---------LLIC------------- ---QFGIGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSTCVLSVH-------QYVTLVPVNRGKGKLVLRASFT------NMASYSS YSC---------WFFSVLSNIHFPIKVSGPQITDNNTD-SKRKLFCST-----SGFSVGI VFLQFAYDATFM-----------SIMV-WTSVSMVLLLRRHRQR----MQHILTPNQN-- ---PRGQAESRATHTILMLVVTFVS---FYLLNFICIMLHALFTH--------------- -SHFF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >101-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVRNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSTCVLSFH-------QFVTPVPLNRGKGKLVLRASVT------NMACYSS YSC---------WFFSVLSNIHIPIKVSGPQITNNNTD-SNRKLFCST-----SGFSVGI VLLQFAYDATFM-----------SIMV-WASVSMVLLLHRHCQR----MQHILTPNQD-- ---ARGQAESRATRTILMLVVTFVS---FYLLNFICIMLHALFMH--------------- -SHFF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >149-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVRNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTRFLTIFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSTCVLSFH-------QFVTPVPLNRGKGKLVLRASVT------NMACYSS YSC---------WFFSVLSNIHIPIKVSGPQITNNNTD-SNRKLFCST-----SGFSVGI VLLQFAYDATFM-----------SIMV-WASVSMVLLLHRHCQR----MQHILTPNQD-- ---ARGQAESRATRTILMLVVTFVS---FYLLNFICIMLHALFMH--------------- -SHFF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >158-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------AKVFLFVRNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSTCVLSFH-------QFVTLVPLNRGKGKLVLRASVT------NMASYSS YSC---------WFFSVLSNIHIPIKVSGPQIKDNNTD-SNRKLFCST-----SGFSVGT VLLQFAYDATFM-----------SIMV-WASVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAESRATRTILMLVVTFVS---FYLLNFICIMLHALFMH--------------- -SHFF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >119-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GKSVKTTEEVAL---QL---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----KQKPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSNCVLGVH-------QFVTLVPLNRGKGKLVLRASVT------NMASYSS YSC---------WFFSVLSNIHIPIKVSGPQITDNNTD-SKRKLFCST-----SGFSVGI VLLQFAYDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQN-- ---PRGQAETRATRTILMLVVTFVS---FYLLNFICIMLHALFMH--------------- -SHFF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >113.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVH-GNSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVCLFVHNFSPVLTG---S-----KQRPRQV-ILRHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLVLRASVT------NMASYSS YSC---------WFFSVLSNIHIPIKFSGPQITDNNTD-SKRKLFCST-----SGFSVGI VFLQFAYDATFM-----------SIMV-WTSVSMVLLLHRHHQR----MQHILTPNQN-- ---PRGQAESKATRTILMLVFTFVS---FYLLNCICIMLHALFMH--------------- -THFF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >113.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVH-GNSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVCLFVHNFSPVLTG---S-----KQRPRQV-ILRHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---ARSTNLCSTCVLSVH-------QFVTLVPVNRGKGKLVLRASVT------NMASYSS YSC---------WFFSVLSNIHIPIKFSGPQITDNNTD-SKRKLFCST-----SGFSVGI VFLQFAYDATFM-----------SIMV-WTSVSMVLLL--------------LTPNQN-- ---PRGQAESKATRTILMLVFTFVS---FYLLNCICIMLHALFMH--------------- -THFF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >117-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GNSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPNDLKCKLESFSHLV- ---VRSTNLCSTCVLSVH-------QFVTLVPLNRGKGKLVLRASVT------NMASYSS YSC---------WFFSVLSNIHIPIKFSGPQITDNNTD-WKRKLFCST-----SGFSVGI VFLQFAYDATFM-----------SIMV-WTSVSMVLLLHRHHQR----MQHILTPNQN-- ---PRSQAQSKATHTILMLVFTFVS---FYLLNCICIILHALFMH--------------- -SHFF-----------VRL------------------VSEILTA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >129-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-GNSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTIFPNNM------------MAFAPKTPPTELKCKLESFSHLV- ---VRSTNLCSTCVLSVH-------QFVTLVPLNRGKGKLVLRASVT------NMASYSS CSC---------WFFSVLSNIHIPIKFSGPQITDNNTD-SKRKLFCST-----SGFSVGI VFLQFAYDATFM-----------SIMV-WTSISMVLLLRRHRQR----MQHILTPNQN-- ---PRGQAESKATHTILMLVFTFVS---FYLLNCICIIVHALFMH--------------- -SHFF-----------VRL------------------VSEILTA---------------- ---I--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal93-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVR-GKSLKTTEEVAL---QL---------LLLC------------- ---QFGVGTM------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTVFPNNM------------MAFAPRNPPTELKCKLKFFSHLV- ---TRSTNLCSTCVLSIH-------QFVTLVPISR--GKLLLRASVP------NLVSYSC YGC---------WFFSVLSYIHIPIKVTGPQITDNNTD-SKSKFFCST-----SGFTVRI VFLQFSHDATFM-----------SIMV-WTSVSMVFLLHRHRQR----MQHILTPNQD-- ---ARGQAESRATHTILMLVVTFVS---FYLLNFICIIFHTFFIH--------------- -YNLF-----------IRL------------------FGEILAA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCLE -------LFHCFKPESLQNLKH-RRQLH-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >126-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVR-GKSLKTTEEVAL---QI---------ILLC------------- ---QFGVGTM------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTVFPNNM------------MAFAPRNPPTELKCKLKFFSHLV- ---TRSTNLCSTCVLSIH-------QFVILVPISR--GKLLLRASVP------NLVSYSC YGC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSKFFCST-----SGFTVRI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQQ----MQHILTPNQD-- ---ARGQAESRATQTILIVVVTFVS---FYLLNFICIIFHTFFIH--------------- -YNLF-----------IRL------------------LGEILAA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCLE -------LFHCFKPESLQNLKH-RRQLH-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >114-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVR-GKSLKTTEEVAL---QI---------ILLC------------- ---QFGVGTM------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTVFPNNM------------MAFAPRNPPTELKCKLKFFSHLV- ---TRSTNLCSTCVLSIH-------QFVILVPISR--GKLLLRASVP------NLVSYSC YGC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSKFFCST-----SGFTVRI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAESRATQTILIVVVTFVS---FYLLNFICIIFHTFFIH--------------- -YNLF-----------IRL------------------LGEILAA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCLE -------LFHCFKPESLQNLKH-RRQLH-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >93-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVR-GKSLKTTEEVAL---QI---------ILLC------------- ---QFGVGTM------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTVFPNNM------------MAFAPRNPPTELKCKLKFFSHLV- ---TRSTNLCSTCVLSIH-------QFVILVPISR--GKLLLRASVP------NLVSYSC YGC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSKFFCST-----SGFTVRI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAESRATHTILMLVVTFVS---FYLLNFICIIFHTFFIH--------------- -YNLF-----------IRL------------------LGEILAA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCLE -------LFHCFKPESLQNLKH-RRQLH-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >121-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVR-GKSLKTTEEVAL---QI---------ILLC------------- ---QFGVGTM------------ANVFLFVHNSSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTVFPNNM------------MAFAPRNPPTELKCKLKFFSHLV- ---TRSTNLCSTCVLSIH-------QFVTLVPISR--GKLLLRASVP------NLVSYSC YGC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSKFFCST-----SGFTVRI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAESRATHTILMLVVTFVS---FYLLNFICIIFHTFFIH--------------- -YNLF-----------IRL------------------LGEILAA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCLE -------LFHCFKPESLQNL---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal93-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVR-GKSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTM------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTVFPNNM------------MAFAPRNPPTELKCKLKFFSHLV- ---TRSTNLCSTCVLSIH-------QFVTLVPISR--GKLLLRASVP------NLVSYSC NGC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSKFFCST-----SGFTVRI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---PRGQAESRATHTILMLVVTFVS---FYLLNFICIIFHTFFIH--------------- -YNLF-----------IQL------------------LGEILAA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--NPCLE -------LFHCFKPESLQNLKH-RRQLH-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal93-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSVR-GKSLKTTEEVAL---QI---------LLLC------------- ---QFGVGTM------------ANVFLFVHNFSPVLTG---S-----KQRPRQV-ILSHM -------AVANALTLFLTVFPNNM------------MAFAPRNPPTELKCKLKFFSHLV- ---TRSTNLCSTCVLSIH-------QFVTLVPISR--GKLLLRASVP------NLVSYSC NGC---------WFFSVLSNIHIPIKVTGPQITDNNTD-SKSKFFCST-----SGFTVRI VFLQFSHDATFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAESRATHTILMLVVTFVS---VYLLNCICIVFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >178.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------MAFAPRNSPTHLKCKLEYFSRLV- ---ARSTNMCSTCVLSIH-------QFVTLVPVNR--GKAILRASVP------NLTSYSC YSC---------WFFSVLSNIYIAIKVTGPQITDNNTD-SKSKLFCFT-----SGFSVGI FFLRIFHDGTFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNFICIIFYTFSID--------------- -SRLF-----------MSH------------------FSKVFAA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--YPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >178.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-DKSLKTTDDMTL---QI---------LLLC------------- ---QFVVGTV------------ANVFLFLHNISPVLTG---S-----KQRPRQL-ILSHM -------SVANALILFLTSFP-DM------------MAFAPRNSPTHLKCKLEYFSRLV- ---ARSTNMCSTCVLSIH-------QFVTLVPVNR--GKAILRASVP------NLTSYSC YSC---------WFFSVLSNIYIAIKVTGPQITDNNTD-SKSKLFCFT-----SGFSVGI FFLRIFHDGTFM-----------SIMV-WTSVSMVLLLHRHRQR----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNFICIIFYTFSID--------------- -SRLF-----------MSH------------------FSKVFAA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--YPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >178.1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-DKSLKTTDDMTL---QI---------LLLC------------- ---QFVVGTV------------ANVFLFLHNISPVLTG---S-----KQRPRQL-ILSHM -------SVANALILFLTSFP-DM------------MAFAPRNSPTHLKCKLEYFSRLV- ---ARSTNMCSTCVLSIH-------QFVTLVPVNR--GKAILRASVP------NLTSYSC YSC---------WFFSVLSNIYIAIKVTGPQITDNNTD-SKSKLFCFT-----SGFSVGI FFLRIFHDGTFM-----------SIMV-WTSVSMVLLLHRHHQQ----MQHILTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLVNFICIIFYTFSVD--------------- -SRLF-----------MSH------------------FSKVFAA---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPK--YPCSV -------LFNC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >178-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-DKSLKTTDDMTL---QI---------LLLC------------- ---QFVVGTV------------ANVFLFLHNISPVLTG---S-----KQRPRQL-ILSHM -------SVANALILFLTSFP-DM------------MAFAPRNSPTHLKCKLEYFSRLV- ---ARSTNMCSTCVLSIH-------QFVTLVPVNR--GKAILRASVP------NLTSYSC YSC---------WFFSVLSNIYIAIKVTGPQITDNNTD-SKSKLFCFT-----SGFSVGI FFLRIFHDGTFM-----------SIMV-WTSVSMVLLLH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >179-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAH-EKFLKNTEEVAL---QI---------LLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQSPRQV-ILSHM -------AVANVLILFITIFPTNV------------MTFAPRNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIY-------QFVTLVPVHR--GKLILRASVP------NLARYSC YSC---------WFFSVLNNIYIPIKVTGPQIADNITD-CRSKLFCFT-----SGYSRVI FFLRIAYDATFM-----------SIMV-WTSVSMVLLLHRHHQK----MQHIFTTNRH-- ---YRGQAETRATCTILMLVVTFVS---FYLLNFTCIILQALVSD--------------- -SHAF-----------VRH------------------WSEALVT---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------KSK--DPCSV -------FFQLLKS---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >179.1-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MS-Y LIITPVSAKALSMCTL-DKSLKTTEEVAL---QI---------FLLC------------- ---QFGVGTV------------TNVFLFVHNFYPVLTG---S-----QQSPRQV-ILSHM -------TVANVLILFITIFPTNV------------MTFAPRNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIY-------HFVTLVPVNR--GKLILRASVP------SLARYSC YSC---------WFFSVLNNIYIPIKVTGPQRADNNTD-CRSKLFCFT-----FGYSRVI FFLRIAYDATFM-----------SIMV-WTSVSMVLLLHRHHQK----MQHIFTTNRH-- ---YRGQAETRATSTILMLVVTFVS---FYLLNFTCIITQALVTD--------------- -SHAF-----------VRH------------------WSEALVT---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------KSK--DPCSV -------FF--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >179.2-s ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MS-Y LIITPVSAKALSMCTL-DKSLKTTEEVAL---QI---------FLLC------------- ---QFGVGTV------------TNVFLFVHNFYPVLTG---S-----QQSPRQV-ILSHM -------TVANVLILFITIFPTNV------------MTFAPRNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIY-------HFVTLVPVNR--GKLILRASVP------SLARYSC YSC---------WFFSVLNNIYIPIKVTGPQRADNNTD-CRSKLFCFT-----FGYSRVI FFLRIAYDATFM-----------SIMV-WTSVSMVLLLHRHHQK----MQHIFTTNRH-- ---YRGQAETRATSTILMLVVTFVS---FYLLNFTCIIAQALVTD--------------- -SHAF-----------VRH------------------WSEALVT---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------KSK--DPCSV -------FF--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >179-m ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MS-Y LIITPVSAKALSMCTL-DKSLKTTEEVAL---QI---------FLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQSPRQV-ILSHM -------AVANILILFITIFPTNV------------MTFAPRNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIY-------QFVTLVPVNR--GKLILRASVP------SLARYSC YSC---------WFFSVLNNIYIPIKVTGPQIADNNTD-CRSKLFCFT-----FGYSRVI FFLRIAYDATFM-----------SIMV-WTSVSMVLLLHRHHHK----MQHIFTTNRH-- ---YRGQAETRATSTILMLVVTFVS---FYLLNFTCIIIQALVTD--------------- -SHAF-----------VRH------------------WSEALVT---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------KSK--DPCSV -------FFRLLKS---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >179-z ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MS-Y LIITPVSAKALSMCTL-DKSLKTTEEVAL---QI---------FLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQSPRQV-ILSHM -------AVANILILFITIFPTNV------------MTFAPRNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIY-------QFVTLVPVNR--GKLILRASVP------SLARYSC YSC---------WFFSVLNNIYIPIKVTGPQIADNNTD-CRSKLFCFT-----FGYSRVI FFLRIAYDATFM-----------SIMV-WTSVSMVLLLHRHHQK----MQHIFTTNRH-- ---YRGQAETRATSTILILVITFVS---FYLLNFTCIIIQALVTD--------------- -SHAF-----------VRH------------------WSEALVT---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------KSK--DPCSV -------FFRLLKS---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >179-x ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MS-Y LIITPVSAKALSMCTL-DKSLKTTEEVAL---QI---------FLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQSPRQV-ILSHM -------AVANILILFITIFPTNV------------MTFAPRNPPTDLKCKLEFFIRLV- ---ARSTNLCSTCVLSIY-------QFVTLVPVNR--DKLILRASVP------SLARYSC YSC---------WFFSVLNNIYIPIKVTGPQIADNNTD-CRSKLFCFT-----FGYSGVI FFLRIAYDATFM-----------SIMV-WTSVSMVLLLHRHHQK----MQHIFTTNRH-- ---YRGQAETRATSTILILVITFVS---FYLLNFTCIIIQALVTD--------------- -SHAF-----------VRH------------------WSEALVT---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------KSK--DPCSV -------FFRLLKS---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >179-p ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MS-Y LIISPVSVKALSTCTL-DKSLKTTEEVAL---QI---------FLLC------------- ---QFGVGTV------------ANVFLFVHNFYPVLTG---S-----QQSPRQL-ILSHM -------AVANALILFVTIFPTNG------------MTFDPRNSPTDLKCKFEFFTRLV- ---ARSTNLCSTCVLSTY-------QFVTLVPVNR--GKLILRASVP------SLARYSC YSC---------WLFSVLNNIYIPMKVTGPQIADNNTD-CRSKMFCFT-----SRYGGVI FFLRIVNDATFM-----------SIMV-WTSISMVLLLHRHHQR----MQHIFTTNQN-- ---HRGQAETRATHTILMLVVTFVS---FYLLNLTCIIVHTFDTD--------------- -SHAF-----------VRH------------------WSEALVT---------------- ---G--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------KSK--DPCSV -------FFQLLKS---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >139.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------MSIF---------------------------------------- -------------ILTEA-------Q---------------------------------- ------------------------------------------------------------ ---KISHDATFM-----------SIMV-WTSVSMVLLL--------------LTPNQD-- ---ARGQAETRATHTILMLVVTFVS---FYLLNCICIIFHAFSIH--------------- -SRLF-----------IRL------------------VSEVLAA---------------- ---V--FP-----------------------S-I--C---P--------------LL--- --------L-------------------------------IFR-------DPN--DPCSV -------LFKC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal167.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------TLFVPKEPPTDLKCKLGYFICLV- ---ARSTNMCSTCSLSTY-------QFFTLAPGTW--GRVMLHGRAP------IFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTYNDTN-IKSKWVCST-----TGFSIGT RILSFTHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSTNQK-- ---LRVHAETRASHTILMLVVTFVT---CYLLDCICSFLHISFVD--------------- -SRLW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPN--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal167.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------TVFVPKEPPTDLKCKLGYFICLV- ---ARSTNMCSTCFLSTY-------QFVTLAPGTW--GRVMLRGRAP------KFVRYTC YSC---------WLFSVVNNAHIPMKVSGPQKTYNDTN-TKNKWVCST-----SGFSIGM HILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSPNQK-- ---LRVHAETRASHTILMLVVTFVT---CYLLDCICSFLHISFVD--------------- -SRLW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPN--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal167.3-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------MCSTCSLSTY-------QFFTLAPGTW--GRVMLRGRAP------KIVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDSN-SKIKWVCST-----SGFSIGT HILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSTNQK-- ---LRVHAETRASHTILMLVVTFVT---CYLLDCICSFLHISFVD--------------- -SRLW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPN--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal167.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKSVKTTEEVAL---QV---------LLLC------------- ---QAGVGTV------------VNIFLFVHNLSPFLND---S-----QQRPIQV-ILVNL -------AVGNTL-ILLFAFPNNM------------TVFIPTEFPTDLKCKLGYFICLV- ---ARSTNMCSTCSLSTY-------QFVTLAPGTW--GRMMLRGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDSN-SKSKWVCST-----TGFSIGM HILSFAHDAVFI-----------SIII-WSSVSMVILLSRHHQR----LQHIQSPNQK-- ---LRVYAETRASHTILMLVVTFVT---CYLLDCICTFLHISFVD--------------- -SRLW-----------LRR------------------VKEILAL---------------- ---S--FP-----------------------T-F--S---P--------------VL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal167.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------TLFVPKDLPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRMMLHGRPP------NFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDTN-TKSKWVCST-----TGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSPNQK-- ---LRVYAETRASHTILMLVVTFVT---CYLLDCICTFLHISFVD--------------- -SRLW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal167.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKSVKTTVEVAL---QI---------LLLC------------- ---QVGVGTV------------VNIFLFVHNLSPFLNG---S-----QQRPIKV-ILANL -------ALGNTL-ILFFAFPNNI------------RVFIPREFPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRMMLHGRPP------NFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDTN-TKSKWVCST-----TGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSPNQK-- ---LRVYAETRASHTILMLVVTFVT---CYLLDCICTFLHISFVD--------------- -SRLW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >169-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKSVKTTVEVAL---QI---------LLLC------------- ---QVGVGTV------------VNIFLFVHNLSPFLNG---S-----QQRPIKV-ILANL -------ALGNTL-ILLFAFPNNI------------RVFIPREFPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRVMLHGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDTN-TKSKWVCST-----TGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSPNQK-- ---LRFHAETRAAHTILMLVVTFVT---CYLLDCICTSLHISFVD--------------- -SRVW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------PFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >176-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKSVKTTVEVAL---QI---------LLLC------------- ---QVGVGTV------------VNIFLFVHNLSPFLNG---S-----QQRPIKV-ILANL -------ALGNTL-ILLFAFPNNI------------RVFIPREFPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRVMLPGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDTN-TKSKWVCST------------ ----------LV-----------SV----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >176-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKSVKTTVEVTL---QI---------LLLC------------- ---QVGVGTV------------VNIFLFVHNLSPFLNG---S-----QQRPIKV-ILANL -------ALGNTL-ILLFAFPNNI------------RVFIPREFPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QFVTLAPGTW--GRVMLPGRAP------NFLRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDSN-SKSKWVCST-----SGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSTNQK-- ---LRVHAETRASHTILLLVVTFVT---CYLLDCICTVCNISFVD--------------- -SRVW-----------LRR------------------VKEILSV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFGC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >170/175.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLLQ-NKSVKTTEEVAL---QV---------LLLC------------- ---QVGFGTA------------VNIFLIVHNLSPILNG---S-----QQRPIKV-ILANL -------AMGNTL-ILLFAFPNNM------------TLFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRVMLRGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDTN-TKNKWVCST-----TGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----VQHIQSTNQK-- ---LRVHAETRASHTILMLVVTFVT---CYLLDCICTFCNISFLD--------------- -SRLW-----------LRR------------------VKEILAD---------------- ---D--AL-----------------------Q-V--H---P------------------- -----------------------------------------FG-------N--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >167.2-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKSVKTTVEVAL---QI---------LLLC------------- ---QVGVGTV------------VNIFLFVHNLSPFLNG---S-----QQRPIKV-ILANL -------AVGNTL-ILLFAFPNNM------------TIFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QFVTLAPGTW--GRVMLRGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDSN-SKSKWVCSN-----SGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSTNQK-- ---LRVHAETRASHTILLLV---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >167.3-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLLQ-NKSVKTTEEVAL---QV---------LLLC------------- ---QVGFGTA------------VNIFLIVHNLSPFLNG---S-----QQRPIKV-ILANL -------AVGNTL-ILLFAFPNNM------------TIFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QFVTLAPGTW--GRVMLRGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDSN-SKSKWVCSN-----SGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSTNQK-- ---LRVHAETRASHTILLLV---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >170/175.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLLQ-NKSVKTTEEVAL---QV---------LLLC------------- ---QVGFGTA------------VNIFLIVHNLSPILNG---S-----QQRPIKV-ILANL -------AMGNTL-ILLFAFPNNM------------TLFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRVMLRGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDTN-TKNKWVCST-----TGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----VQHIQSTNQK-- ---LRVHAETRASHTILMLVVTFVT---CYLLDCICTFCNISFLD--------------- -SRLW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >175-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLLQ-NKSVKTTEEVAL---QV---------LLLC------------- ---QVGFGTA------------VNIFLIVHNLSPILNG---S-----QQRPIKV-ILANL -------AVGNTL-ILLFAFPNNM------------TLFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCFLSTY-------QLVTLAPGTW--GRVMLRGRAP------KFVRYIC YSC---------WLFSVLNNAHIPMKVNGPQKTHNDTN-TKNKWVCST-----TGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSTNQK-- ---LRVHAETRASHTILLLVVTFVT---CYLLDCICTVCNISFLD--------------- -SRVW-----------LRR------------------VKQILDV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFCC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >170-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLLQ-NKSVKTTEEVAL---QV---------LLLC------------- ---QVGVGTA------------VNIFLIVHNLSPNLNG---S-----QQRPIKV-ILANL -------AVGNTL-ILLFAFPNNM------------TLFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRVMLRGRAP------KFVRYIC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDTN-TKNKWVCST-----TGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHHR----LQHIQSTNQK-- ---LRVHAESRASHTILMLVVTFVT---CYHLDCICTFCNISFLD--------------- -SQLW-----------LRR------------------VKQILDA---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFCC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >171.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKSVKTTEEVAL---QI---------LLLC------------- ---QVGVGTA------------VNIFLIVHNLSPILNG---S-----QQRPIKV-ILANL -------AVGNTL-ILLFAFPNNM------------TLFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRVMLRGRAP------KFVRYIC YSC---------WLSSVLNNAHIPMKVSGPQKTHNDTN-TKNKWVCST-----TGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSPNQK-- ---LRVHAETRAAHTILMLVVTFVT---CYLLDCICTFLHISFVD--------------- -SRLW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPN--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >171.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MITIPLTNEVVSMLSQ-NKSVKTTEEVAL---QI---------LLLC------------- ---QVGVGTA------------VNIFLIVHNLSPILNG---S-----QQRPIKV-ILANL -------AVGNTL-ILLFAFPNNM------------TLFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRVMLRGRAP------KFVRYIC YSC---------WLSSVLNNAHIPMKVSGPQKTHNDTN-TKNKWVCST-----TGFSIGM RILSFAHDAVFI-----------SIII-WSSVSMVILLNRHHQR----LQHIQSPNQK-- ---LRVHAETRAAHTILMLVVTFVT---CYLLDCICTFLHISFVD--------------- -SRLW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPN--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >167.5-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MITIPLTNEVVSMLSQ-NKSVKTTEEVAL---QI---------LLLC------------- ---QVGVGTA------------VNIFLIVHNLSPILNG---S-----QQRPIKV-ILANL -------AVGNTL-ILLFAFPNNM------------TLFVPKDLPNDLKCKLGYFIWLV- ---ARNTNMCSTCSLSTY-------QFVTLAPGTW--GRVMLRGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDSN-SKSKWVCSN-----SGFSIGM RILSFAHDAVFI-----------SIII-RSSVSMVILLNRHHQR----LQHIQSPNQK-- ---LRFYAETRAAHTILMLVVTFVT---CYLLDCICTFLHISFVD--------------- -SRLW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >167.4-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------M------------TIFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QFVTLAPGTW--GRVMLRGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDSN-SKSKWVCSN-----SGFSIGM RILSFAHDAVFI-----------SIII-RSSVSMVILLNRHHQR----LQHIQSPNQK-- ---LRFYAETRAAHTILMLVVTFVT---CYLLDCICTFLHISFVD--------------- -SRVW-----------LRR------------------VKEILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFSC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >167-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MI-IPLSNEVVSMLSQ-NKSVKTTEEVAL---QI---------LLLC------------- ---QVGVGTA------------VNIFLIVHNLSPILNG---S-----QQRPIKV-ILANL -------AVGNTL-ILLFAFPNNM------------TIFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRVMLLGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDTN-SKSKWVCST-----SGFSIGM RILSFAHDGVFI-----------SIII-WSSVSMVILLNRHHQR----LQYIQSPNQK-- ---LRVHAETRAAHTILMLVVTFVT---CYLLDCICTFCHIYFVD--------------- -SRLW-----------LRR------------------VNQILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFCC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >167.1-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKSVKTTEEVAL---QI---------LLLC------------- ---QVGVGTA------------VNIFLIVHNLSPNFNG---S-----QQRPIKV-ILANL -------AVGNTL-ILLFAFPNNM------------TIFVPKDPPTDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QFVTLAPGTW--GRVMLRGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDTN-SKSKWVCST-----SGFNIGM RILSFAHDGVFI-----------SIII-WSSVSMVILLNRHHQR----LQYIQSPNQK-- ---LRVHAETRAAHTIVMLVVTFVT---CYLLDCICTFCHIYFVD--------------- -SRLW-----------LRR------------------VNQILAV---------------- ---S--FP-----------------------T-F--S---P--------------LL--- --------L-------------------------------IFR-------DPK--DPCSL -------LFCC------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >169/176-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MITIPLTNEVVSMLSQ-NKSVKTTEEVAL---QI---------LLLC------------- ---QVGVGTA------------VNIFLIVHNLSPILNG---S-----QQRPIKV-ILANL -------ALGNTL-ILLFAFPNNM------------TLFVPKDLPNDLKCKLGYFIWLV- ---ARSTNMCSTCSLSTY-------QLVTLAPGTW--GRVMLPGRAP------KFVRYTC YSC---------WLFSVLNNAHIPMKVSGPQKTHNDTS-INSKWV--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------A---P--------------LL--- --------V-------------------------------SV------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal167.2-p -M---------------SIKHFPDIAP------------------ALSYSSSI------- ---------------------------LL-------------------------GEKDS- --------------------KSVQRL-R------KLR-------------RQSKIELS-N LIIIPLSNEVISMLSH-NKTLKTKEEMAL---HI---------FLLC------------- ---QVGVGTV------------ANFLLFIHNFSAILTN---C-----QLTPIQV-LVTNL -------AVASAFNLLLLAILNSR------------TVFLPRKPPSDLSCKLWYFICLV- ---ARSTNLSSTCVLSTY-------QFVTLLPGKW--SRVMLRGRAP------KIVSYSC YSC---------WIFSVLNNAYIPMEVNGPQKTHNDTD-FKDKWVCSI-----SGFSVGM SFLRFAHDTVFI-----------SIMI-WTNVSMAILLKRHHHR----MQHIHSSNQD-- ---HRVYADTRAAHTILMLVVTFVS---FYLLDCICTFFHISFVD--------------- -SRLL-----------LRH------------------VKEVLNA---------------- ---S--FP-----------------------T-I--S---P--------------FL--- --------L-------------------------------IFR-------DPK--NPCSL -------LFRG------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal58.3-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTMEDLAL---QI---------LFLC------------- ---HVMVGTG------------GNILLFVHNFSPILTD---S-----RLRPIQV-ILINL -------ALTNALMLFLSTYSHDM------------IDFVPRKPPAELKCKLAYFFHMV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYSC FSC---------WLFSVLNNAYIPMNVSGPQKTHNDSD-SKGNSICSI-----SGVSVDM NVLRFSHDIIFL-----------SIMA-WTSVSMVIHLKRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILFHISFVE--------------- -SRLW-----------LR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal58.1-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLPQ-NKTLKTMEMLAL---QI---------LLLC------------- ---HVVVGTV------------GNILQFVHNFSPILTD---S-----RLKPIQV-ILINL -------AVANAFMLLLFAYSYDL------------TDIVPRKPPTDLKCKLAYFFHMV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYSC FSC---------WLFSVLNNAYIPMNVSGPQKTHNDSD-SKGNSICSI-----SGVSVDM NVLRFSHDIIFL-----------SIMA-WTSVSMVIHLKRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILFHISFVE--------------- -SRLW-----------LR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >58-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTMEMLTL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSPILTD---S-----RLKPIQV-ILINL -------AVANAFMLLLFAYSYDL------------TDIVPRKPPTDLKCKLAYFFHMV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYCC CSC---------WLFSVLNNAYIPMNVSGPQKSHNDSD-SKGNSICSI-----SGVSVDM NVLRFSHDIIFL-----------SIIA-WTSVSMVIHLHRHHQR----MNHIHKANQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILFHISFVE--------------- -SRLW-----------LRY------------------ATKLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DRK--GHCSL -------HIIVSMGI------------HVTGGAIT---EGQKGQNTA------------- ------------------------------------------------------------ --------------------------------KP-------------------------- ------------- >58-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEMLAL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSPILTD---S-----RLKPIQV-ILINL -------AVANAFMLLLFAYSYDL------------TDIVPRKPPTDLKCKLAYFFHMV- ---ARGTIMCSTCILSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYCC CIC---------WLFSVLNNAYIPMNVSGPQKSHNDSD-SKGNSICSI-----SGVSVDM NILRFSHDIIFL-----------SIMA-WTSVSMVIHLHRHHQR----MNHIHKANQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCITILFHISFVE--------------- -SRLW-----------LRY------------------ATKLLAL---------------- ---S--FP-----------------------T-I--S---P--------------FL--- --------L-------------------------------IFR-------DRK--GHCSL -------HIIVSMGI------------HVTGGAIT---EGQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal58.2-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MKPSPGSLLKTMEMLAL---QI---------LLFC------------- ---HVVVGTV------------GNILLFVHNFSQILTE---S-----RLKPIQV-ILINL -------AVANAFMILLFVYSYEM------------IDIVSMKPPTDLKCKLAYFFHLV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYSC FSC---------WLFSVLNNAYIPMNVSGPQKTHNDSD-SKGNSICSI-----SGVSVDM NVLRFSHDIIFL-----------SIMA-WTSVSMVIHLKRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILFHISFVE--------------- -SRLW-----------LR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >61-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEMLAL---QI---------FLLC------------- ---HVVVGTV------------GNILQFVHNFSQILTD---S-----RLKPIQV-ILINL -------AVANAVMLLLFAYSYDM------------IDFVPRKPPTDIKCKLAHFFHLV- ---ARGTIMCSTCVLSTY-------QFVTLVPGNW--ARVMFREISP------KVVSYSC FSC---------WLFSILNNAYMPMYVSGPQKSHNDSD-S--NWICSI-----SGVSVDM SVLRFSHDIIFL-----------SIMA-WTSVSMVIHLNRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILLHFFFVE--------------- -FRLW-----------MRY------------------VTNLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DCK--GHCSL ------HIMSVWKFM--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >61-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEMLAL---QI---------LLLC------------- ---HVVVGTV------------GNILQFVHNFSRILTD---S-----RLKPIQV-ILINL -------AVANAIMLLLFAYSYDM------------IDFVPRKPPTEVKCKLAHFFHLV- ---ARGTIMCSTCVLSTY-------QFVTLVPGNW--ARVMFREISP------KVVSYSC FSC---------WLFSILNNAYMPMYVSGPQKSHNDSD-SKDNWICSI-----SGVSVDM NILRFSHDIIFL-----------SIMA-WTSVSMVIHLHRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILLHISFVE--------------- -FRLW-----------TRY------------------VINLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DCK--GHCSV ------HIMSVWKSM--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >63-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEMLAL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSQILTD---S-----RLRPIQV-ILINL -------AVANAFMLLLFAYSYDL------------TDIVPRKPPTDLKCKLAYFFHLV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFSEISP------KVVSYCC YSC---------WLFSVLNNAYMLMNVSGPQKSHNDSD-SKGNSICSI-----SGVSVDM NFLRFSHDIIFL-----------SIMA-WTSVSMVIHLNRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---SYTLNCISISFHISFVE--------------- -SCLW-----------LRY------------------VTKLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DCK--GHCSL ------RIMSVWKSI--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >187-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEMLAL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSQILTD---S-----RLRPIQV-ILINL -------AVANAFMLLLFAYSYDL------------TDIVPRKPPTDLKCKLAYFFHLV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFSEISP------KVVSYCC YSC---------WLFSVLNNAYMLMNVSGPQKSHNDSD-SKGNSICSI-----SGVSVDM NFLRFSHDIIFL-----------SIMA-WTSVSMVIHLNRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---SYTLNCISISFHISFVE--------------- -SCLW-----------LRY------------------VTKLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DCK--GHCSL ------RIMSVWKSI--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >63/187-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTMEMLAL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSQILTD---S-----RLRPIQV-ILINL -------AVANAFMLLLFAYSYDM------------IDFVPRKPPTDVKCKLAHFFHLV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYCC YSC---------WLFSVLNNAYMLMNVSGPQKSHNDSD-SKGNSICSI-----SGVSVDM NFLRFSHDIIFL-----------SIMA-WTSVSMVIHLNRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---SYTLNCISILFYISFVE--------------- -SRLW-----------LRY------------------VTKLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DCK--GHCSL ------HIMSVWKSM--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >62-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEVLAL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSPILTD---S-----RLRPIQV-ILINL -------AVANAFMLLLFAYSYDL------------TDIVPRKPPTDLKCKLAYFFHLV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFSEISP------KVVSYCC YSC---------WLFSVLNNAYMLMNVSGPQKSHNDSD-SKSNSICSI-----SGVSVDM NILRFSHDIIFL-----------SIMA-WTSVSMVIHLHRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILFYISFVE--------------- -SRLW-----------LRY------------------VTKLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DSK--GHCSL ------HIMSVWKST--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >186-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEVLAL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSPILTD---S-----RLRPIQV-ILINL -------AVANAFMLLLFAYSYDL------------TDIVPRKPPTDLKCKLAYFFHLV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFSEISP------KVVSYCC YSC---------WLFSVLNNAYMLMNVSGPQKSHNDSD-SKSNSICSI-----SGVSVDM NILRFSHDIIFL-----------SIMA-WTSVSMVIHLHRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILFYISFVE--------------- -SRLW-----------LRY------------------VTKLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DSK--GHCSL ------HIMSVWKST--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >62/186-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEVLTL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSPILTD---S-----RLRPIQV-ILINL -------AVANAFMLLLFAYSYDL------------TDIVPRKPPTDLKCKLAYFFHMV- ---ARSTNMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYCC YSC---------WLFSVLNNAYMLMNVSGPQKSHNDSD-SKGNSICSI-----SGVSVDM NFLRFSHDIIFL-----------SIMA-WTSVSMVIHLNRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILFYISFVE--------------- -SRLW-----------LRY------------------VTKLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DCK--GHCSL ------HIMSVWKSM--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >60/61-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLLLFAYSYDL------------TDIVPRKPPTDLKCKLAYFFHMV- ---ARSTNMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYCC YSC---------WLFSVLNNAYMLMNVSGPQKSHNDSD-SKGNSICSI-----SGVSVDM NFLRFSHDIIFL-----------SIMA-WTSVSMVIHLNRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILLHISFVE--------------- -FRLW-----------MRY------------------VTNLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DCK--GHCSL ------CIMSVWKST--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >60-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEMLAL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSPILTD---S-----RLRPIQV-ILINL -------AVANAFMLLLFAYSYDL------------IDIVPRKPPTDLKCKLAYFFHLV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFSEISP------KVVSYCC YSC---------WLFSVLNNAYMPMYVSGPQKTHNDSD-SKGNSICSI-----SGVSVDM NVLRFSHDIIFL-----------NIMA-WTSVSMVIHLNRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILLHFSFVE--------------- -FRLW-----------MRY------------------VTNLLSL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DCK--GHCSV ------HIMSVWKSM--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >59-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MFREISP------KVVSYSC FSC---------WLFSVLHNAYIPMNVSGPQKTHNDSD-SKGNWICSI-----SGVNVDM HFLRFSHDIIFL-----------GIMA-WTSVSMMIHLNRHHQR----MNCIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILFHISFVE--------------- -SRLW-----------SRH------------------VIKILAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GHCSL -------LFSVGLEI------------HVNGGVIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >59-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEMLAL---QI---------LLLC------------- ---QVVVGTV------------GNILLFVHNFSPVLTD---S-----RLRPIQV-ILINL -------AVANAFMLLLLTYSHDM------------IDFVPRKPPTDLKCKLAYFFHMV- ---AQGTIMCSTCVLSTY-------QFVTVVPGTW--ARVMFREISP------KVVSYSC FSC---------WLFSVLHNAYIPMNVSGPQKTHNDSD-SKGNSICSI-----SGVNVDM HFLRFSHDIIFL-----------GIMA-WTSVSMMIHLNRHHQR----MNRIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILFHISFVE--------------- -SRLW-----------SRH------------------VIKVLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GHCSL -------LFSVGLEI------------HVTGGVIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >57-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEVLAL---NI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSPNLTD---S-----RLRPIQV-ILINL -------AVANAFMLLFSTYSYDL------------IDFVPRKPPTDLKCKLAYFFHMV- ---ARGTIMCSTCVLSTY-------QFVTLVPGNW--ARVMFREISP------KVVSYSC FSC---------WLFSVLNNAYIPMNVSGPQKSHNDSD-SKDNWICSI-----SGVSVDM NFLRFSHDIIFL-----------GIMA-WTSVSMVIHLNRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCIIILFHITFVE--------------- -SRLS-----------LRH------------------VTKLLSL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------EPR--GHCSL -------LFSVGLEI------------HVTGGVIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal58-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MLLLFAYSYDL------------TDIVPRKPPTDLKCKLAYFFHMV- ---ARSTNMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYCC YSC---------WLFSVLNNAYMLMNVSGPQKSHNDSD-SKGNSICSI-----SGVSVDM NFLRFSHDIIFL-----------SIMA-WTSVSMVIHLNRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILFHISFVE--------------- -SRLW-----------SRH------------------VIKVLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GHCSL -------LFSVRLEI------------HVTGGVIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >58-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLPQ-KKTLKTMEELTL---QI---------LLPC------------- ---HVVVGTV------------GNILLFVHNFSPILTD---S-----RLRPIQV-ILTNL -------AVANAFMLLLSTYSHDL------------IDFVPRKPPTDLKCKLAYFFHMV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMIREISP------KVVSYCC YSC---------WLFSVLYNVHIPMNVSGPKKSLNDSD-SKGNLICSI-----SGVSVDM NFLRFSHDIIFL-----------GIMA-WTSVSMVIHLNRHHQR----VNHIHKLKQN-- ---NRGHAEIRAAHTILMLVVTFVS---LYILNCISILFHISFVE--------------- -SRLW-----------LRY------------------VTKLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DRK--GYCSL -------LIIVGLEI------------HLTGGAIT---EGQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal58.4-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEVLAL---HI---------LLLC------------- ---QVVVGTV------------GNILLFVHNFSPILND---S-----RLRPIHV-ILINL -------AVANAFMLLLSTYSHDM------------IDFVPRKPPTDLKCKLAHFFHMM- ---ARGTNMCSTCVLSTY-------QFVTLVPGNW--ARVMFREISP------KVVSYSC FSC---------WLFSVLNNAYIPMNVSGPQKTHNDSD-SKGNSICSI-----SGVSVDM NVLRFSHDIIFL-----------SIMA-WTSVSMVIHLKRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILDCIFILFHISFVE--------------- -SGLW-----------LRH------------------VIQLMTL---------------- ---N--FP-----------------------T-I--S---P--------------FL--- --------L-------------------------------IFR-------DPR--GP--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >56-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEVLAL---HI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSPILTD---S-----RLRPIQV-ILINL -------AVANAFMLLLLTYSHDM------------IDFVPKNPPTDLKCKLAYFFHMV- ---ARGTNMCSTCVLSTY-------QFVTLVPGNC--ARVMFREISP------KVVSYSC FSC---------WLFSVLNNAYIPMNVSGPQKSHNDTD-SKGNCICSV-----SGVSVDM NFFRFSHDIMFL-----------SIMA-WTSVSMVIHLNRHHQR----MHYIHNHNHK-- ---NTGHAETRAAHTILMLVVTFVS---LYILDCICILFHISFVE--------------- -SRLW-----------LRH------------------VIQLMTL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GHCSL -------LFSVGLEI------------HMTRGDIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >60/61-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MVITPLCNEAISTLSQ-NKIMRTTEEVAL---QI---------LLLC------------- ---QAGVGIL------------GNILLFLHNFSPILTD---S-----QLRPIQI-IQTNL -------AVANTFILLFLTFPNHM------------AVLAPRKPPTDLKCKLAYFFHMV- ---ARGTIMCSTCVLSTY-------QFVTLVPGNW--ARVMFREISP------KVVSYSC FSC---------WLFSVLNNAYIPMNVSGPQKSHNDSD-SKGNSICSI-----SGVSVDM NFLRFSHDIIFL-----------SIMA-WTSVSMVIHLNRHHQR----MNHIHKVNQN-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCISILLHISFVE--------------- -FRLW-----------MRY------------------VTNLLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DCK--GHCSL ------RIMSVQKST--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >55-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MFREISP------KVVSYCC YSC---------WLFSVLNNAYIPMNVSGPQKSHNDSD-SKGNWICSI-----SGVSVDM IFLRFSHDIIFI-----------GIMV-WTSVSMVIHLNRHHQR----MHYIHNPNQS-- ---NRGHAETRAAYTILMLVVTFVS---LYILNCICVLFHISFVE--------------- -SRLW-----------LRD------------------VIEFLAI---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------M-------------------------------IFR-------DPR--GPCSL -------FFIVGLEI------------HVTGKVIT---K--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >64.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MFREISP------KVVSYCC YSC---------WLFSVLNNAYIPMNVSGPQKSHNDSD-SKGNWICSI-----SGVSVDM IFLRFSHDIIFI-----------GIMV-WTSVSMVIHLNRHHQR----MHYMQNPNQN-- ---NRGHAETRAAQTILMLVVTFVS---LYILDCICSLFHISFVE--------------- -SCLW-----------LID------------------VIELLHL---------------- ---S--FP-----------------------T-V--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GPCSL -------LIIVGLEI------------HVTGGAIT---EGQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >64.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MFREISP------KVVSYCC YSC---------WLFSVLNNAYIPMNVSGPQKSHNDSD-SKGNWICSI-----SGVSVDM IFLRFSHDIIFI-----------GIMV-WTSVSMVIHLNRHHQR----MHYMQNPNQN-- ---NRGHAETRAAQTILMLVVTFVS---LYILDCICSLFHISFVE--------------- -SCLW-----------LID------------------VIELLHL---------------- ---S--FP-----------------------T-V--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GPCSL -------LIIVGLEI------------HVTGGAIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >64-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTMEVLAL---QI---------LLLC------------- ---HVVVGTV------------GNILLFLHNFSPVLTD---S-----RLRPIQV-ILINL -------AVANAFMLLLFAYSYDL------------IDFVPRKPPTDLKCKLAYFFNMV- ---AQGTIMCSTCLLSTY-------QFVTLVPGNW--ARVMFREISP------KVVSYCC YSC---------WLFSVLNNAYMPMYVSGPQKTHNDSD-SKDNWICSI-----SGVSVDM NFLRFFHDIIFI-----------GIMA-WTSVSMVIHLNRHHHR----MHYLHNPNQI-- ---NRGHAETKAAHTIMMLVVTFVS---LYILDCICSLFHISFVE--------------- -SRLW-----------LID------------------VIELLHI---------------- ---S--FP-----------------------T-V--S---P--------------FL--- --------L-------------------------------ICR-------DPM--GPCSL -------LFIVGLEI------------HVTVGAIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >64-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTMEVLAL---QI---------LLLC------------- ---QVVVGTV------------GNIFLFVHNFSPVLTD---S-----RLRPIQV-ILINL -------AVANAFMLLLFAYSYDL------------IDFVPRKPPTDLKCKLAYFFNMV- ---AQGTIMCSTCLLSTY-------QFVTLVPGNW--ARVMFREISP------KVVSYCC YSC---------WLFSVLNNAYMPMYVSGPQKTHNDSD-SKDNWICSI-----SGVSVDM NFLRFSHDIIFI-----------GIMA-WTSVSMVIHLNRHHHR----MHYLHNPNQI-- ---NRGHAETKAAHTIMMLVVTFVS---LYILDCICSLFHISFVE--------------- -SRLW-----------LID------------------VIELLHL---------------- ---S--FP-----------------------T-V--S---P--------------FL--- --------L-------------------------------ICR-------DPM--GPCSL -------LFIVGLEI------------HVTVGAIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >64-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTMEVLAL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSPILTD---S-----RLRPIQV-ILINL -------AVANAFMLLLFAYSYDL------------IDFVPRKPPTDLKCKLAYFFNMV- ---AQGTIMCSTCLLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYCC YSC---------WLFSVLNNAYMLMNVSGPQKSHNDSD-SKGNSICSI-----SGVSVDM NFLRFSHDIIFL-----------GIMA-WTSVSMVIHLNRHHHR----MRYLHNPNQI-- ---NRGHAETKAAHTIMMLVVTFVS---LYILDCICSLFHISFVE--------------- -SRLW-----------LID------------------VIELLHL---------------- ---S--FP-----------------------T-V--S---P--------------FL--- --------L-------------------------------ICR-------DPM--GPCSL -------LFIVGLEI------------HVTVGAIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal56.3-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MFREITP------KVVSYSC YSC---------WLFSVLNNAYIPVNFSGPQKSHNNSD-SKGNWICSI-----SGVSVDM NFLRFSHDIIFI-----------GIMA-WTSASMVIHLNKHHQR----MHYLHNPNQN-- ---NRVHAETRAAHTILMLVVTFVS---LYILNCICIVFHISFIE--------------- -SRLW-----------LRD------------------VIEFLTL---------------- ---C--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GPWSL -------LIIVGLEI------------HVTGEDIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >55.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MFREISP------KVVRYSC YSC---------WLFSVLNNAYIPMNVRGPKKSHNDSD-SQGKRMCST-----SVVNVDM NYLQFSYDIIFI-----------GIMV-WTSVSMVIHLNRHHQR----MHYIHNPNQS-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCICVLFHISFVE--------------- -SRHW-----------LRN------------------VIEFLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GPCSL -------YLNIGLEI------------HVTGKVIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >55-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEVLAL---QI---------LLLC------------- ---QVVVGTV------------GNILLFVHNFSPVLTD---S-----RLRPIQV-ILINL -------AVANAFMLLLLTYSHDM------------IDFVPRKPPTDLKCKLAHFFHMM- ---ARGTNMCSTCVLSIY-------QFVTLVPGNW--ARVMFREISP------KVVRYSC YSC---------WLFSVLNNAYIPMNVRGPKKSHNDSD-SQGKRMCSI-----SVVNVDM NYLQFSYDIIFI-----------GIMV-WTNVSMVIHLNRHHQR----MHYIHNPNQS-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCICVLFHISFVE--------------- -SRHW-----------LRN------------------VIEFLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GPCSL -------YFNIGLEI------------HVTGKVIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >55-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEMLAL---QI---------LLLC------------- ---QVVVGTV------------GNILLFVHNFSPILTD---S-----RLRPIQV-ILINL -------AVANAFMLLLLTYSHDM------------IDLVPKNPPTDLKCKLAHFFHMV- ---ARGTNMCSTCVLSTY-------QFVTLVPGNW--ARVMFREISP------KVVRYSC YSC---------WLFSVLNNAYIPMNVRGPKKSHNDSD-SQGKRMCSI-----SVVNVDM NYLQFSYDIIFI-----------GIMV-WTSVSMVIHLNRHHQR----MHYIHNPNQS-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCICVLFHVSFVE--------------- -SRRW-----------LRN------------------VIEFLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GPCSL -------YFNVGLEI------------HVTGKVIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >55-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTMEMLAL---QI---------LLLC------------- ---HVVVGTV------------GNILLFVHNFSPVLTD---S-----RLRPIQV-ILINL -------AVANAFMLLLLTYSHDM------------IDFVPRKPPTDLKCKLAHFFHMM- ---AQGTNMCSTCVLSIY-------QFVTLVPGNR--ARVMFREISP------KVVRYSC YSC---------WLFSVLNNAYIPMNVRGPKKSHNDSD-SQGKRMCSI-----SVVNVDM NYLQFSYDIIFI-----------GIMV-WTSVSMVIHLNRHHQR----MHYIHNPNQS-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCITILFHISFVE--------------- -SRHW-----------LRN------------------VIEFLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GPCSL -------YFNIGLEI------------HVTGKVIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >55.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTMEMLAL---QI---------LLLC------------- ---QVVVGTV------------GNILLFVHNFSPVLTD---S-----RLRPIQV-ILINL -------AVANAFMLLLLTYSHDM------------IDFVPRKPPTDLKCKLAHFFHMV- ---ARGTNMCSTCVLSIY-------QFVTLVPGNW--ARVMFREISP------KVVRYSC YSC---------WLFSVLNNAYIPMNVRGPKKSHNDSD-SQGKRMCST-----SVVNVDM NYLQFSYDIIFI-----------GIMV-WTSVSMVIHLNRHHQR----MHYIHNPNQS-- ---NRGHAETRAAHTILMLVVTFVS---LYILNCICVLFHISFVE--------------- -SRHW-----------LRN------------------VIEFLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--VLVLC -------TSILGLKS------------M-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal56.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTVEELAL---QI---------LLLC------------- ---QVVLGTV------------GNILLFVHNFSPILND---S-----RLRPIQV-ILINL -------AVANAFMLLLLTYSYDQ------------IDFVPRKPPTDLRCKLAYFFHIV- ---ARGTIMCSTCVLSTY-------QFITLVPGTW--ARVMFREITP------KVVSYSC YSC---------WLFSVLNNAYIPVNFSGPQKSHNNSD-SKGNWICSI-----SGVSVDM NFLRFSHDIIFL-----------GIMA-WTSVSMVIHLNRHHQR----MNHIHNPNHN-- ---SRGHAETRAAHTILMLLATFVS---LYILDCTCSLFYISFVE--------------- -SRLW-----------LRH------------------VIKVLSL---------------- ---S--FP-----------------------T-I--S---P--------------FL--- --------L-------------------------------IFR-------DPR--GPCSL -------LIIMGLEI------------QVTGGAIT---AEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal56.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTVEELAL---QI---------LLLC------------- ---QVVLGTV------------GNILLFVHNFSPILND---S-----RLRPIQV-ILINL -------AVANAFMLLLLTYSYDQ------------IDFVPRKPPTDLRCKLAYFFHIV- ---ARGTIMCSTCVLSTY-------QFITLVPGTW--ARVMFREITP------KVVSYSC YSC---------WFLSVLNNVYIPMNVSGPQKSHNYTD-SKGKWMCYT-----SRVSVDV NFFRFSHDIIFI-----------GIMA-WTSVTMVIRLNRHHQR----MHYIHNPNHK-- ---NTGHAETRAAHTILMLVVTFVS---LYILDCTFILFHISFVE--------------- -SRLW-----------LRH------------------VIELMTL---------------- ---T--FP-----------------------T-I--S---P--------------LL--- --------M-------------------------------IFR-------DPR--GPWSL -------LVIVGLEI------------HVTRGDIT---EEE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal55.2-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTMEELAL---QI---------LLLC------------- ---QVVVGIL------------GNILLFVHNFSPILTN---T-----RLRPKQV-ILTNL -------AVVNAFMLLLLTYSYDI------------IDFVPKKPPTDLKCKLAYFFNMV- ---VRGTNMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KAVSYSC YSC---------WLWNVLNNAYIPMNAGVLQKSHNDTD-SKGMWMCFT-----SGVSVGT NFL---HDIIFI-----------GIMV-WTSVSMMMHLSRHHQR----MHHIHNSSQN-- ---NRGHAETRAAHTILMIVVTFVT---LYILNCISILVHISFVE--------------- -SRLW-----------LVD------------------VIKVLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GPYSL -------FFIFGLEI------------LVTEKVIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal55.1-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MLSQ-NKTLKTVEELAL---QI---------LLLC------------- ---QVVLGTV------------GNILLFVHNFSPILND---S-----RLRPIQV-ILINL -------AVANAFMLLLLTYSYDL------------IDFVLRKPPTDLNCKLAYFLHMV- ---ARGTIMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KAVSYSC YSC---------WLWNVLNNAYIPMNAGVLQKSHNDTD-SKGMWMCFT-----SGVSVGT NFL---HDIIFI-----------GIMV-WTSVSMMMHLSRHHQR----MHHIHNSSQN-- ---NRGHAETRAAHTILMIVVTFVT---LYILNCISILVHISFVE--------------- -SRLW-----------LVD------------------VIKVLAL---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPR--GPYSL -------FFIFGLEI------------LVTEKVIT---EEQ------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >65-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MVITPLCNEAISMLSQ-NKIIRTTEEVAL---QI---------LLLC------------- ---QSGVGIL------------GNILLFLHNFSPILTD---S-----QLKPIQI-IQTNL -------AVANTFILLFLTFPNHM------------AVLAPRKPPTDLKCKLAYFFHMV- ---ARSTNMCSTCVLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYSC YSC---------WLFSVLNNAYIPMNVSGPQKTHNGTD-SKGKWVCST-----SGFNVGM SFLRFAQDIIFI-----------STMI-WTSVSIVLHLNRHHQR----MHCIHNTSRK-- ---FRTCAETRAAHTVLMLVVTFVS---FYLLDCICTFFHISFVN--------------- -TRFW-----------LRH------------------VKEVLTL---------------- ---S--FP-----------------------T-I--S---P--------------LM--- --------L-------------------------------IFR-------DPR--GPCPV -------PFIVGLQS------------HVTGISSL---EQE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >65.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MVITPLCNEAISTLSQ-NKIMKTTEEVAL---QI---------LLLC------------- ---QAGVGIL------------GNILLFLHNFSSILTD---S-----QLRPIQI-IQTNL -------TVANTFFLLFLTFPNHM------------AVLAPRKPPTDLKCKLAYFFHMV- ---ARSTNMCSTCVLSTY-------QFVTLVPGTW--ARVIFREISP------KVVSYSC YSC---------WLFSVLNNAYIPMNVSGPQKTDNDTD-SKGKWVCST-----SGFNVGM SFLQFAQDIIFI-----------STMI-WTSVSIVLHLNRHHQR----MHYIHNTSQK-- ---FRAYAETRAAHTVLMLVVTFVS---FYLLDCICTFFHISFVN--------------- -TRFW-----------LRH------------------VKEVLTV---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPM--CPCPV -------PFIVGLQS------------RVTGISSL---EQE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >65.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MVITPLCNEAISTLSQ-NKIMKTTEEVAL---QI---------LLLC------------- ---QAGVGIL------------GNILLFLHNFSSILTD---S-----QLRPIQI-IQTNL -------TVANTFFLLFLTFPNHM------------AVLAPRKPPTDLKCKLAYFFNMV- ---AQGTIMCSTCLLSTY-------QFVTLVPGTW--ARVIFREISP------KVVSYSC YSC---------WLFSVLNNAYIPMNVSGPQKTDNDTD-SKGKWVCST-----SGFNVGM SFLQFAQDIIFI-----------STMI-WTSVSIVLHLNRHHQR----MHYIHNTSQK-- ---FRAYAETRAAHTVLMLVVTFVS---FYLLDCICTFFHISFVN--------------- -TRFW-----------LRH------------------VKEVLTV---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPM--CPCPV -------PFIVGLQS------------RVTGISSL---EQE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >65-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MVITPLCNEAISTLSQ-NKIMRTTEEVAL---QI---------LLLC------------- ---QAGVGIL------------GNILLFLHNFSPILTD---S-----QLRPIQI-IQTNL -------AVANTFILLFLTFPNHM------------AVLAPRKPPTDLKCKLAYFFHMV- ---ARSTNMCSTCVLSTY-------QFVTLVPGTW--ARVIFREISP------KVVSYSC YSC---------WLFSVLNNAYIPMNVSGPQKTDNGTD-SKGKWVCST-----SGFNVGM SFLQFAQDIIFI-----------STMI-WTSVSIVLHLNRHHQR----MHYIHNTSQK-- ---FRAYAETRAAHTVLMLVVTFVS---FYLLDCICTFFHISFVN--------------- -TRFW-----------LRH------------------VKEVLTV---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPM--CPCPV -------PFIVGLQS------------RVTGISSL---EQE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >65-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MVITPLCNEAISTLSQ-NKIMRTTEEVAL---QI---------LLLC------------- ---QAGVGIL------------GNILLFLHNFSPILTD---S-----QLRPIQI-IQTNL -------AVANTFILLFLTFPNHM------------AVLTPRKPPTDLKCKLAYFFHMV- ---ARSTNMCSTCVLSTY-------QFVTLVPGTW--ARVIFREISP------KVVSYSC YSC---------WLFSVLNNAYIPMNVSGPQKTDNGTD-SKGKWVCST-----SGFNVGM SFLQFAQDIIFI-----------STMI-WTSVSIVLHLNRHHQR----MHYIHNTSQK-- ---FRACAETRAAHTVLMLVVTFVS---FYLLDCICTFFHISFVN--------------- -TRFW-----------LRH------------------VKEVLTV---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPM--CPCPV -------PFIVGLQS------------RVTGISSL---EQE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >65-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------MRTTEEVAL---QI---------LLLC------------- ---QAGVGTL------------GNIFLFLHNFSPILTD---S-----QVRPIQI-IQTNL -------AVANTFILLLLTFPNHM------------AVLAPRKPPTDLTCKLAYFFHMV- ---ARSTNMCSNCVLSTY-------QFVTLVPGTW--ARVMFREISP------KVVSYCC YSC---------WLFSVLNNAYIPMNVSGPQKSHNGTD-SKAKWVCST-----SGFSVGM SFLRFAQDIIFI-----------STMI-WTSVSIVLHLNRHHQR----MHYIHNTSQK-- ---FRSCAETRAAHTVLMLVVTFVS---FYLLDCICTFFHVSFVN--------------- -TRFW-----------LRH------------------VKEVLTV---------------- ---S--FP-----------------------T-I--S---P--------------LM--- --------L-------------------------------IFR-------DPM--CPCPV -------PFIVGLQS------------HVIGISSL---EQE------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >basal55.3-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MEEVAL---QI---------LVLC------------- ---HVGPGTM------------ANALLFVHNFSPILTD---S-----QLRPIQV-ILTNL -------AVANVFILLLLGFTNNM------------AVLDSSKTPTDLRCKLIYFMYLV- ---ARGTNMCSTCVLSAY-------QFVTLIPHNW--GRVLLRGRAT------SVVSYSC YSC---------WLFSVLNNAYIPMKVTGPQKTHNDTD-VKGKQVCSI-----SDFSVGM NFLRFAHDIMFI-----------SIMV-WTNISMVLLLRKHHQR----LQHIQISFQG-- ---HRGYAETRASHTILMLVVTFVN---FYLLDCICTFFHISFAN--------------- -TCLW-----------LRH------------------VKEVLAV---------------- ---S--FP-----------------------T-I--S---P--------------LI--- --------L-------------------------------ILR-------DPK--DPCSL -------LFSVQP-------------------------EEPD------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >90-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MFSQ-NEAMKTTEEVAL---QI---------VLFC------------- ---QFGIGTM------------ANILLFVHNFSPLLTG---C-----QLRPKQV-ICTNM -------AVSSILILFMAVFSNNV------------FV-AQRNLMNDLQCKLEYFLHMV- ---ARSINLCSTCVLSTY-------QFVTLLPGNF--GELMVRGRRS------KVISYSC CSC---------WLFGVLYNVYIPMKVSGPQNTHNKTG-IKYKWLCFT-----SGFSVGI LFLWFVHDAIFI-----------SIMV-WTSVSMVIILYRHYER----LQYIFSHHQG-- ---TRGYAEIRAAHSIAMLVVTFVS---FYLLHCICFILHVVFVD--------------- -SRLW-----------LRH------------------VGEFLSS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YPCSL -------IFNYRKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >90.3-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NEAMKTTEEVAL---QI---------VLLC------------- ---QFGIGTM------------ANIFLFIHNFSPLLTG---C-----QLRPKQV-ICTNM -------AVSSILILFMTVFPNNV------------FV-VQRNLMNDLQCKLEYFLRMV- ---ARSINLCSTCVLSTY-------QFVTLLPGNF--GEMMVRGRRS------KVISYSC CSC---------WLFGVLYNVYIPMKVSGPQSTHNKTD-IKSKWFCVT-----SGFSVGI VFLWFAHDAIFI-----------SIMI-WTSVSMVLLLYRHYQR----LQYIFPPHQG-- ---TRGYAEIRAVHSIAMLVVTFVS---FYLLHCICFILHIVFVD--------------- -SRLW-----------LRH------------------VGEVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YPCSL -------IFNYRKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >90.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NEAMKTTEEVAL---QI---------VLLC------------- ---QFGIGTM------------ANILLFIHNFSPLLTG---C-----QLRPKQV-ICTNM -------AVSSILILFMTVFPNNV------------FV-VQRNLMNDLQCKLEYFLRMV- ---ARSINLCSTCVLSTY-------QFVTLLPGNF--GEMMVRGRRS------KVISYSC CSC---------WLFGVLYNVYIPMKVSGPQSTHNKTD-IKSKWFCVT-----SGFSVGI VFLWFAHDAIFI-----------SIMI-WTSVSMVLLLYRHYQR----LQYIFPPHQG-- ---TRGYAEIRAVHSIAMLVVTFVS---FYLLHCICFILHIVFVD--------------- -SRLW-----------LRH------------------VGEVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YPCSL -------IFNYRKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >90.4-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NEAMKTTEEVAL---QI---------VLLC------------- ---QFGIGTM------------ANILLFIHNFSPLLTG---C-----QLRPKQV-ICTNM -------AVSSILILFMTVFPNNV------------FV-VQRNLMNDLQCKLEYFLRMV- ---ARSINLCSTCVLSTY-------QFVTLLPGNF--GEMMVRGRRS------KVISYSC CSC---------WLFGVLYNVYIPMKVSGPQSTHNKTD-IKSKWFCVT-----SGFSVGI VFLWFAHDAIFI-----------SIMI-WTSVSMVLLLYRHYQR----LQYIFPPHQG-- ---TRGYAEIRAVHSIAMLVVTFVS---FYLLHCICFILHIVFVD--------------- -SRLW-----------LRH------------------VGEVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YLCSL -------IFNYRKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >90.1-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------MKTTEEVAL---QI---------VLLC------------- ---QFGIGTM------------ANILLFIHNFSPLLTG---C-----QLRPKQV-ICTNM -------AVSSILILFMTVFPNNV------------FV-VQRNLMNDLQCKLEYFLRMV- ---ARSINLCSTCVLSTY-------QFVTLLPGNF--GEMMVRGRRS------KVISYSC CSC---------WLFGVLYNVYIPMKVSGPQNTHNKTD-IKSKWFCVT-----SGFSVGI MFLWFAHDAIFI-----------SIMI-WTSVSMVLLLYRHYQR----LQYIFPPHQG-- ---TRGYAEIRAAHSIAMLVVTFVS---FYLLHCICFILHIVFVD--------------- -SRLW-----------LRH------------------VGEVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YPCSL -------IFNYRKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >90.3-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NEAMKTTEEVAL---QI---------VLLC------------- ---QFGIGTM------------ANILLFIHNFSPLLTG---C-----QLRPKQV-ICTNM -------AVSSILILFMTVFPNNV------------FV-VQRNLMNDLQCKLEYFLRMV- ---ARSINLCSTCVLSTY-------QFVTLLPGNF--GEMMVRGRRS------KVISYSC CSC---------WLFGVLYNVYIPMKVSGPQNTHNKTD-IKSKWFCVT-----SGFSVGI MFLWFAHDAIFI-----------SIMI-WTSVSMVLLLYRHYQR----LQYIFPPHQG-- ---TRGYAEIRAAHSIAMLVVTFVS---FYLLHCICFILHIVFVD--------------- -SRLW-----------LRH------------------VGEVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YPCSL -------IFNYRKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >90.2-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MNDLQCKLEYFLRMV- ---ARSINLCSTCVLSTY-------QFVTLLPGNF--GEMMVRGRRS------KVISYSC CSC---------WLFGVLYNVYIPMKVSGPQNTHNKTD-IKSKWFCVT-----SGFSVGI MFLWFAHDAIFI-----------SIMI-WTSVSMVLLLYRHYQR----LQYIFPPHQG-- ---TRGYAEIRAAHSIAMLVVTFVS---FYLLHCICFILHIVFVD--------------- -SRLW-----------LRH------------------VGEVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YPCSL -------IFNYRKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >168/177.1-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NGAMKTTEEVAL---QI---------VLFC------------- ---QFGIGTM------------ANILLFVHNFSPLLTA---C-----QLRPKQV-ICTNM -------AVSSILILSMTVFPNNV------------FV-AQRNPLNDLQCKLEYFVYMV- ---ARSTNLFSTCVLSTY-------QFVTLVPGNF--SELMVRGRSR------KVISYSC CSC---------WLFGILYNVYIPMKVSGPQNRHNKTS-TKSKWVCFT-----SGFSVGI VFLSFAHDAIFI-----------SIMV-WASVSMVLLLYRHYQR----LQYIFPPHQG-- ---NRGYAEIRAAHSIVMLVVTFVS---FYLLHCICFILHIVFVD--------------- -SHLW-----------LRH------------------IGKVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YHCSL -------IFNCKKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >168/177.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NGAMKTTEEVAL---QI---------VFLC------------- ---QFGIGTM------------ANILLFVHNFSPLLTA---C-----QLRPKQV-ICTNM -------AVSSILILFMTVFPNNV------------FV-AQRNPLNDLQCKIEYFVYIV- ---ARSTNLCSTCVLSTY-------QFVTLVPGNF--SELMVRGRSP------KVISYSC CSC---------WLFGVLYNVYIPMKVRGPQNTHNKSS-TKSKWVCFT-----SGFSVSI VFLSFAHDAIFI-----------SIMV-WASVSMVLLLYRHYQR----LQYIFPPHQG-- ---NRGYAEIRAAHSIVMLVVTFVS---FYLLHCICFILHIVFVD--------------- -SHLW-----------LMH------------------IGEVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YHCSL -------IFNYKKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >168-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NGAMKTTEEVAL---QI---------VLLC------------- ---QFGIGTM------------ANILLFVHNFSPLLTG---C-----QLRPKEV-ICANM -------AVSSILILFMTVFPNNV------------FV-AQRNLLNDLQCKLEYFVYMV- ---ARSTNLCSTCVLSTY-------QFVTLVPGNF--SELMVRGRSP------KVISYSC CSC---------WLFGILYNVYIPMKVSGPQNRHNKTS-TKSKWVCFT-----SGFSVGI VFLSFAHDAIFI-----------SIMV-WASVSMVRLLYRHYQR----LQYIFPPHQG-- ---NRGYAEIRAAHSIVLLVVTFVS---FYLLHCICFILHIVFVD--------------- -SNLW-----------LRH------------------IGEVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YPCSL -------IFNYKKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >168.1-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NGAMKTTEEVAL---QI---------VLLF------------- ---QFGIGTM------------ANILLFVHNFSPLLTG---C-----QLRPKEV-ICTNM -------AVSSILILFMTVFPNNV------------FV-AQRNPLNDLQCKLEYFVYMV- ---ARSTNLCSTCVLSTY-------QFVTLVPGNF--SELMVRGRSP------KVISYSC CSC---------WLFGILYNVYIPIKVSGPQKRHNKTS-TKSKWVCFT-----SGFSVGI VFLSFAHDAIFI-----------SIMV-WASVSMVLLLYRHYQR----LQYIFPPHQG-- ---NRGYAEIRAAHSIVMLVVTFVS---FYLLHCICFILHIVFVD--------------- -SHLW-----------LRH------------------IGEVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YPCSL -------IFNYKKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >177-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NGAMKTTEEVAL---QI---------VLLC------------- ---QFGIGTM------------ANILLFVHNFSPLLTG---C-----QLRPKEV-ICTNM -------AVSSILILFMTVFRNNV------------FV-AQRNPLNDLQCKLEYFVYMV- ---ARSTNLCSTCVLSTY-------QFVTLVPGNF--NELMVRGRSP------KVISYSC CSC---------WLFGVLYNVYIPMKVSGPQNRHNKTS-TKSKWVCFT-----SGFSVGI VFLSFAHDAIFI-----------SIMV-WASVSMVLLLYRHYQR----LQYIFPPHQG-- ---NRGYAEIRAAHSIVMLVVTFVS---FYLLHCISFILHIVFVD--------------- -SHLW-----------LRH------------------IGEVLTS---------------- ---S--FP-----------------------T-I--S---P--------------LL--- --------L-------------------------------IFR-------DPS--YHCSL -------IFNYKKPVI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >90/168/177-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NEAMKTTEEVAL---QI---------VLLC------------- ---QFGIGSM------------ANILLFVHNFSPLLNE---C-----QLRPKQV-ICTNM -------AVSSILILFMTVFPNNV------------FV-AQRNPPNDLQCKLEYFVYMV- ---ARSTNLCSTCVLSTY-------QFVTLVPGNF--GKLMVRGRRP------KVISYFC GSC---------WLFGVLYNVYIPIKVSGPQNTNNKTS-IKSKWVCFT-----SGFSVGI VFLSFAHDAI-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >90-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NEAMKTTEEVAL---QV---------ILLC------------- ---QFVIGTM------------ANLLLLVHNFSPLLTG---C-----QLRPKQV-ICTHM -------AVSSILILFMTVFPNNV------------FV-AQRNPVNDLQCKLEYSLRIL- ---ARSINLCSTSVLSTY-------QFVTLVPGNF--GELKVRGRSP------KVISYSC CSC---------WLFGVLYNVYIPMKVSGPQNTHNKTG-IKNKWVCFR-----SGFSVGI MFLWFAHDAIFI-----------SIMI-WTSVSMVLLLYRHSQR----LQYIFPPHQG-- ---TRGYGEIRAAHSIVMLVVTFVS---FYLLHCVCFILHIVFVD--------------- -SHLW-----------LRH------------------VGEVLSS---------------- ---S--FP-----------------------S-V--S---P--------------LL--- --------L-------------------------------ILR-------DPS--YPCYL -------ICNY------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >90.2-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NEAMKTTEEVAL---QI---------VLLC------------- ---QFGIGTM------------ANILLFIHNFSPLLTG---C-----QLRPKQV-ICTNM -------ALSSILILFMTVFPNNV------------FV-VQRNLMNDLQCKLEYFLRMV- ---ARSINLCSTCVLSTY-------QFVTLLPGNF--GEMMVRGRRS------KVISYSC CSC---------WLFGVLYNVYIPMKVSGPQTHIIKLT-LK------V-----SG----- ------------------------------------------------------------ ------------------------------------SVLHLASV---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >168.2-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NGAMKTTEEVAL---QI---------VLLF------------- ---QFGIGTM------------ANILLFVHNFSPLLTG---C-----QLRPKEV-ICTNM -------AVSSILILFMTVFPNNV------------FV-AQRNPLNDLQCKLEYFVYMV- ---ARSTNLCSTCVLSTY-------QFVTLVPGNF--SELMVRGRSP------KVISYSC CSC---------WLFGILYNVYIPMKVSGPQNTHNKTD-IK------------------- --------------------------------SGMASWYNHSGN-----QFGSSPENW-- ---T------------------------WYYLR-IQQYVHI------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------P--RRCFN -------IL--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >168.3-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSSQ-NGAMKTTEEVAL---QI---------VLLF------------- ---QFGIGTM------------ANILLFVHNFSPLLTG---C-----QLRPKEV-ICTNM -------AVSSILILFMTVFPNNV------------FV-AQRNPLNDLQCKLEYFVYMV- ---ARSTNLCSTCVLSTY-------QFVTLVPGNF--SELMVRGRSP------KVISYSC CSC---------WLFGILYNVYIPMKVSGPQNRHNKTS-TK------------------- --------------------------------SWNASLYNHFGN-----QFDISSENW-- ---T------------------------WY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >172/173/174-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAL-SKALKTTEEVAL---QI---------ILLC------------- ---QVGIAAV------------ANILLLVHNLSPNFAG---P-----QLRPKHV-ILAHI -------AVGNLLIILLTGFPSNM------------TVFVPRKPLNDLSCKLEYFIRLV- ---ARSANMCTTCVLSTY-------QFIILVPGKW--SRVILKVNAS------TFVHYSC NSC---------WIICVLNNVYIPIKISGPWNTDNDTD-PNSKWVCSN-----SGFELVM VFLRFVHDAIFI-----------SIMV-WTSVSMMLLLYRHHQS----LKHIHRSNRS-- ---LGLQPEARAAYTILMLVVTFVC---FYLLDCICIFFHISFVH--------------- -FRVW-----------LRH------------------VSGILAA---------------- ---S--FP-----------------------T-I--S---P--------------LM--- --------L-------------------------------IFR-------DPK--KYQLK -------------------------G---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >172-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAL-NKALKTTEEVAL---QI---------ILLC------------- ---QVGIAAV------------ANILLLVHNLSPNFAG---P-----QLRPKHV-ILAHI -------AVGNLLIILLTGFPSNM------------TVFVPRNPLNHLNCKLEYFIRLV- ---ARSANMCTTCVLSTY-------QFIVLVPGKW--SRVILRGNTS------TFVHYSC NSC---------WIISVLNNVYIPIKISGPWNTDNNTD-PNSKWVCSN-----SGFELVM VFLRFVHDAIFI-----------SIMV-GTSVSMMLLLYRHHQS----LKHIHRSNGS-- ---LGLQPEARAAYTILMLVITFVC---FYLLDCICIFFHISFVN--------------- -FRVW-----------LRH------------------VSGILAA---------------- ---S--FP-----------------------T-L--S---P--------------LM--- --------L-------------------------------IFR-------GPK--KISAK -------------------------GINTENAFIN---SH-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >172-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAL-NKALKTTEEVAL---QI---------ILLC------------- ---QVGIAAV------------ANILLLVHNLSPNFAG---P-----QLRPKHV-ILAHI -------AVGNLLIILLTGFPSNM------------TVFVPRNPLNNLNCKLEYFIRLV- ---ARSANMCTTCVLSTY-------QFIVLVPGKW--SRVILRGNTS------TFVHYSC NSC---------WIISVLNNVYIPIKISGPWNTDNDTD-PNSKWVCSN-----SGFELVM VFLRFVHDAIFI-----------SIMV-WTSVSMMLLLYRHHQS----LKHIHRSNGS-- ---LGLQPEARAAYTILMLVITFVC---FYLLDCICIFFHISFVH--------------- -FRVW-----------LRH------------------VSGIWAA---------------- ---S--FP-----------------------T-I--S---P--------------LM--- --------L-------------------------------IFR-------GPK--KISAK -------------------------GINTENAFIN---SH-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >174-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAL-NKALKTTEEVAL---QI---------ILLC------------- ---QVGIAAV------------ANILLLVHNLSPNFAG---P-----QLRPKHV-ILAHI -------TVGNLLIILLTGFPSNM------------TVFVPRNPLNDLNCKLEYFIRLV- ---ARSANMCTTCILSSY-------QFIVLVPGKW--SRVILRGNTS------TFVHYSC NSC---------WIISVLNNVYIPIKISGPWNTDNNTD-PNSKWVCSN-----SGFELVM VFLRFVHDAIFI-----------SIMV-WTSVSMMLLLYRHHQS----LKHIHRSNGS-- ---LGLQPEARAANTILMLMITFVC---FYLLDCICIFFHISFVH--------------- -FRVW-----------LRH------------------VSEILAA---------------- ---S--FP-----------------------T-I--S---P--------------LM--- --------L-------------------------------IVR-------GPR--KISAK -------------------------GINTENAFIN---SH-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >172-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAL-NKTLKTIEEVAL---QI---------IMLC------------- ---QVGIAAV------------ANILLLVHNLSSNFAG---T-----QLRPKHV-ILAHI -------AVGNLLIILLTGFPSNM------------TVFVPRNPLNNLNCKLEYFIRLV- ---ARSANMCTTCVLSTY-------QFIVLVPGKW--SRVILRGNTS------TFVHYSC NSC---------WIISVLNNVYIPIKISAPWNTDNDTD-LNSKWVCSI-----SGFELVM VFLRFVHDAIFI-----------SIMV-WTSVSMMLLLYRHHES----LKHIHRSNGS-- ---LGLQPEARAAYTILMLVITFVC---FYLLDCICIFFHISFVH--------------- -FRVW-----------LRH------------------VSGILAA---------------- ---S--FP-----------------------T-I--S---P--------------LM--- --------L-------------------------------IFR-------GPK--KISAK -------------------------GINTENDFIN---SH-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >173-m ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAL-NKALKTTEEVAL---QI---------ILLC------------- ---QVGIAAV------------ANILLLVHNLSPNFAG---P-----QLRPKHV-ILAHI -------TVGNLLIILLTGFPSNI------------IVFVPRNPLNDLNCKLEYFIRLV- ---ARSANMCTTCVLSTY-------QFIVLVPGKW--SRMILRGNTS------TFVHYSC NSC---------WIISVLNNVYIPIKISGPWNTDNDTD-LNSKWVCSM-----SGFELVM VFLRFVHDTMFI-----------SIMV-WTSVSMMLLLYRHHQS----LKHIHRSNGS-- ---LGLQPEARAAYTILMLVVTFVC---FYLLDCMCIFFHISFVH--------------- -FRVW-----------LRH------------------VNEILAA---------------- ---S--FP-----------------------T-L--S---P--------------LM--- --------L-------------------------------IFR-------GPK--KISAK -------------------------GINTENAFIN---SH-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >173-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSAL-NKALKTTEEVAL---QI---------ILLC------------- ---QVGIAAV------------ANILLLVHNLSPNFAG---P-----QLRPKHV-ILAHI -------TVGNLLIILLTGFPSNM------------TVFVPRNPLNDLNCKLEYFIRQV- ---ARSANMCTTCVLSTY-------QFIVLVPGKW--SRVILRGNTS------TFVHYSC NSC---------WIISVLNNVYIPIKISGPWNTDNDTD-LNSKWVCSI-----SGFELVM VFLRFVHDAIFI-----------SIMV-WTSVSMMLLLYRHHQS----LKHIHRSNGS-- ---LGLQPEARAAYTILILVVTFVC---FYLLDCICIFFHISFMH--------------- -FRVW-----------LKH------------------VSEILAA---------------- ---S--FP-----------------------SHL--F---P--------------SL--- --------L-------------------------------IYL---------E--KFTA- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >172/173/174-p ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MSTH-HEALKTTEEVAL---QI---------ILLC------------- ---QVGIATV------------ANILLFVHNLSPQFTG---P-----QLRPKHV-ILAHI -------AVGNVLIILLTGFPSNM------------TVFAPRKPLNDLNCTLEYFIRLV- ---ARSANMCSTCVLSTY-------QFIALVPGKW--SRVIHREKAS------TFVHYSC NSC---------WIISVLNNVYIPIKISGPWNTDNNTD-PNNKWLCSN-----SGFESVM VSLRFVHDAIFI-----------SIMI-WTSVSMILLLYRHGQS----LRHIHRSNGN-- ---LRFPPEARAAHTILMVMVTFVC---FYLLDCICIIFHFTFVQ--------------- -SHIW-----------LRH------------------VSEVLAA---------------- ---S--FP-----------------------T-I--S---P--------------IM--- --------L-------------------------------IFR-------DPK------- -------------------------NINQRD-------KHRKCFN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------- >249-c ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGF----------DCIF---RL---------LFLV------------- ---QNIVGPL------------GHAIVLTVSASMPYIS---Q-----ESRPTRL-ILTNI -------AIGNFFI-LFKGIAYSV------------YICGITHILRIHWFNVVVYMYRV- ---GQGLSLCTTCLLSNF-------QAMSISSRVC-VWM-GLKIQA-------WKISISC FLC---------WISSLLINTFGPVYIECFQHKQNLTK-MWDFRLCIS--QVSRISEGRY RVLITLSDYILI-----------GLMV-FASFYMVLLLYRYQGR----VRLFDSFSIS-- ---KRLSSKAKATQSILLLTSIFIL----------------------------------- ------------------------------------------------------------ ------FNF----------------------T--K-S------------------IL--- --------I-------------------------------LKN-------DTN-F----I ---------------------------------------SQ------------------Y LI---------------------------------------------------------- ------------------------------------------------------------ ------------- >249-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGF----------DCIF---RL---------LFLV------------- ---QNVVGPL------------GHAIVLTVSASMPYIS---Q-----ESRPTRL-ILTNI -------AIGNFFILLFKGI---V------------YICGITHILRIHWFKVLVYIYKV- ---GQHLSLCTTCLLSNF-------QAMSISPRVC-VWM-GLKIQV-------WKISISC FLC---------WISSFLINTFGPVYIEYFQHEQNSTK-MWDFRLCIS--QESRISEGRY RVLITLSDYILI-----------GLMV-CASFYMVLLLYRYQGR----VRLFDSFSIS-- ---KRLSSKAKATQSILLLISIFIL----------------------------------- ------------------------------------------------------------ ------FNF----------------------T--K-S------------------IL--- --------I-------------------------------LKN-------DTK-F----V ---------------------------------------SQ------------------Y LI---------------------------------------------------------- ------------------------------------------------------------ ------------- >249-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGF----------DCIF---RL---------LFLV------------- ---QNVVGPL------------GHAIVLTVSASMSYIS---Q-----ESRPTRL-ILTNI -------AIGNFFILLFKGI---V------------YICGITHILRIHWFKVLIYIYKV- ---GQHLSLCTTCLLSNF-------QAMSISPRVC-VWM-GLKIQV-------WKISISC FLC---------WISSFLINTFGHVYIECFQYEQNSTK-MWDFRLCIS--QVSRISEGRY RVLITLSDYILI-----------GLMV-CASFYMVLLLYRYQGR----VRLFDSFSIS-- ---KRLSSKAKATQSILLLISIFIL----------------------------------- ------------------------------------------------------------ ------FNF----------------------T--K-S------------------IL--- --------I-------------------------------LKN-------DTK-F----V ---------------------------------------SQ------------------Y LI---------------------------------------------------------- ------------------------------------------------------------ ------------- >249-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGF----------DCIF---RL---------LFLV------------- ---QNVVGPL------------GHAIVLTVSASMSYIS---Q-----ESRPTRL-ILTNI -------AIGNFFILLFKGI---V------------YICGITHILRIHWFKVLVYIYKV- ---GQHLSLCTTCLLSYF-------QAMSISPRVC-VWM-GLKIQV-------WKISISC FLC---------WISSFLINTFGPVYIECFQYEQNSTQ-MWDFRLCIS--QVSRISEGRY RVLITLSDYILI-----------GLMV-CASFYMVLLLYRY------------SF-LT-- ---HSVSPKDCPLRLKLHKASCF------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------- >248-s ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MRF----------DFLL---KL---------LFLV------------- ---QNVVGVL------------GNVIVLAVYASMSYTS---R-----ESRPTCL-ILTNM -------AIGNFFI-LFRSTAHSI------------YIWGITHILRIHWLKVVIYMYRV- ---GQGLSLCNTCLLSNF-------QAMPISPKVG-GWV-GIKSQA-------WKISISC FLC---------WISSLLINIFSPLHIECFQNKQNLTN-MWDYRFCSC--QVSSTSEGRC RVHMTLSDFLLV-----------GYMI-CANIYMVHLLYRHQRR----VRLFDSFSVS-- ---QSL---------KLHKAYYF------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------QQ------------------A S----------------------------------------------------------- ------------------------------------------------------------ ------------- >248-x ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MRF----------DFLL---KL---------LFLV------------- ---QNVVGVL------------GNVIVLAVYASMSYTS---R-----ESRPTCL-ILTNM -------ALGNFFI-LFRSTAHSI------------CIWGITHILRIHWLKVVIYMYRV- ---GQSLSLCNTCLLSDF-------QAMPISPKVG-GWV-GIKSQA-------WKISISC FLC---------WISSLLINIFSPLHIECFQNKQNLTN-MWDYRFCSC--QVSSTSEGRC IVHMTLSDFILV-----------GHMV-CASIYMVHLLYRHQRR----VRLFDSFSVS-- ---QSL---------KLHKAYYF------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------QQ------------------A S----------------------------------------------------------- ------------------------------------------------------------ ------------- >248-z ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MRF----------DFLL---KL---------LFLV------------- ---QNVVGVL------------GNVIVLAVYASMSYTS---R-----ESRPTCL-ILTNM -------ALGNFFI-LFRSTAHSI------------CIWGITHILRIHWLKVVIYMYRV- ---GQGMSLCNTCLLSDF-------QAMPISPKVG-GWV-GIKSQA-------WKISISC FLC---------WISSLLINIFSPLHIECFQNKQNLTN-MWDYRFCSC--QVSSTSEGRC IVHMTLSDFILV-----------GHMV-CASIYMVHLLYRHQRR----VRLFDSFSVS-- ---QSL---------KLHKAYYF------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------QQ------------------A S----------------------------------------------------------- ------------------------------------------------------------ -------------