{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["Table S9 -IPA pathway analysis"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Table S9 -IPA pathway analysis","index":0,"n_rows":1333,"n_cols":7,"rows_kept":1333,"flags":["formulas_cached_only"]}
[]
[null,"Additional file 12: Table S9. Pathway analysis using Ingenuity Pathway Analysis software."]
[]
[null,"Ingenuity Pathway Analysis"]
[]
[null,"Category","Function","Function Annotation","p-value","Molecules","# Molecules"]
[1,"Cellular Assembly and Organization","perturbation","perturbation of mitochondrial membrane","1,43E-05","FOXO3, HIP1","2"]
[null,"Cellular Assembly and Organization","quantity","quantity of pedicels","2,21E-03","LMX1B","1"]
[null,"Cellular Assembly and Organization","quantity","quantity of focal complexes","1,10E-02","MAP2K5","1"]
[null,"Cellular Assembly and Organization","quantity","quantity of cilia","3,48E-02","FTO","1"]
[null,"Cellular Assembly and Organization","axonal transport","arrest in axonal transport of mitochondria","4,41E-03","PARK2","1"]
[null,"Cellular Assembly and Organization","development","development of sperm head","4,41E-03","CLIP1","1"]
[null,"Cellular Assembly and Organization","disruption","disruption of mitochondrial membrane","4,41E-03","FOXO3","1"]
[null,"Cellular Assembly and Organization","formation","formation of pedicels","4,41E-03","LMX1B","1"]
[null,"Cellular Assembly and Organization","formation","formation of perinuclear vesicles","4,41E-03","HIP1","1"]
[null,"Cellular Assembly and Organization","formation","formation of Lewy bodies","1,32E-02","PARK2","1"]
[null,"Cellular Assembly and Organization","formation","formation of sarcomere","2,19E-02","MAP2K5","1"]
[null,"Cellular Assembly and Organization","formation","formation of artificial clathrin cages","2,83E-02","HIP1","1"]
[null,"Cellular Assembly and Organization","formation","formation of aggresome","3,48E-02","PARK2","1"]
[null,"Cellular Assembly and Organization","stabilization","stabilization of cytoplasmic microtubule","4,41E-03","CLIP1","1"]
[null,"Cellular Assembly and Organization","orientation","orientation of microtubules","8,80E-03","CLIP1","1"]
[null,"Cellular Assembly and Organization","fusion","fusion of chromosome ends","1,10E-02","SMG6","1"]
[null,"Cellular Assembly and Organization","reorganization","reorganization of cell-cell contacts","1,10E-02","ETV5","1"]
[null,"Cellular Assembly and Organization","function","function of cytoskeleton","1,32E-02","HIP1","1"]
[null,"Cellular Assembly and Organization","elongation","elongation of mitochondria","1,75E-02","PARK2","1"]
[null,"Cellular Assembly and Organization","localization","localization of mitochondria","2,83E-02","PARK2","1"]
[null,"Cellular Assembly and Organization","accumulation","accumulation of mitochondria","3,05E-02","PARK2","1"]
[null,"Cellular Assembly and Organization","dynamics","dynamics of microtubules","3,48E-02","CLIP1","1"]
[2,"Cellular Compromise","perturbation","perturbation of mitochondrial membrane","1,43E-05","FOXO3, HIP1","2"]
[null,"Cellular Compromise","neurodegeneration","neurodegeneration of dopaminergic neurons","1,28E-03","PARK2, SCARB2","2"]
[null,"Cellular Compromise","neurodegeneration","neurodegeneration of outer hair cells","2,41E-03","GRID1, SCARB2","2"]
[null,"Cellular Compromise","neurodegeneration","neurodegeneration of hippocampal neurons","3,69E-02","PARK2","1"]
[null,"Cellular Compromise","peroxidation","peroxidation of protein","2,21E-03","PARK2","1"]
[null,"Cellular Compromise","swelling","delay in swelling of mitochondria","2,21E-03","PARK2","1"]
[null,"Cellular Compromise","damage","damage of red blood cells","4,41E-03","FOXO3","1"]
[null,"Cellular Compromise","disruption","disruption of mitochondrial membrane","4,41E-03","FOXO3","1"]
[null,"Cellular Compromise","degeneration","degeneration of type IV fibrocyte","1,32E-02","GRID1","1"]
[null,"Cellular Compromise","degeneration","degeneration of neurons","2,61E-02","GRID1, PARK2, SCARB2","3"]
[null,"Cellular Compromise","formation","formation of Lewy bodies","1,32E-02","PARK2","1"]
[null,"Cellular Compromise","atrophy","atrophy of myotube","1,54E-02","FOXO3","1"]
[null,"Cellular Compromise","atrophy","atrophy of myofiber","3,48E-02","FOXO3","1"]
[3,"Cell Death and Survival","cell death","cell death of granule cells","3,52E-05","FOXO3, KCNK3, MAP2K5, PARK2","4"]
[null,"Cell Death and Survival","cell death","cell death of embryonic tissue","4,56E-04","KAT8, TAL1, TCF7L2","3"]
[null,"Cell Death and Survival","cell death","cell death of brain cells","7,46E-04","FOXO3, HIP1, KCNK3, MAP2K5, PARK2","5"]
[null,"Cell Death and Survival","cell death","neuronal cell death","7,53E-04","ELAVL4, FOXO3, HIP1, KCNK3, LMX1B, MAP2K5, PARK2, RPTOR","8"]
[null,"Cell Death and Survival","cell death","cell death of hippocampal neurons","1,55E-02","FOXO3, KCNK3","2"]
[null,"Cell Death and Survival","cell death","cell death of cardiomyocytes","1,72E-02","FOXO3, MAP2K5, PARK2","3"]
[null,"Cell Death and Survival","cell death","cell death of cerebral cortex cells","2,13E-02","FOXO3, HIP1, KCNK3","3"]
[null,"Cell Death and Survival","cell death","cell death of lymphoblastoid cell lines","2,13E-02","GBE1, NT5C2","2"]
[null,"Cell Death and Survival","cell death","cell death","2,59E-02","CALCR, ELAVL4, ETV5, FOXO3, GBE1, GRID1, HIP1, KAT8, KCNK3, LMX1B, MAP2K5, NT5C2, PARK2, RPTOR, SCARB2, TAL1, TCF7L2","17"]
[null,"Cell Death and Survival","necrosis","necrosis of embryonic tissue","1,17E-03","TAL1, TCF7L2","2"]
[null,"Cell Death and Survival","necrosis","necrosis of brain cancer cell lines","6,57E-03","FOXO3, HIP1, MAP2K5","3"]
[null,"Cell Death and Survival","necrosis","necrosis of skeletal muscle cells","2,19E-02","PARK2","1"]
[null,"Cell Death and Survival","neurodegeneration","neurodegeneration of dopaminergic neurons","1,28E-03","PARK2, SCARB2","2"]
[null,"Cell Death and Survival","neurodegeneration","neurodegeneration of outer hair cells","2,41E-03","GRID1, SCARB2","2"]
[null,"Cell Death and Survival","neurodegeneration","neurodegeneration of hippocampal neurons","3,69E-02","PARK2","1"]
[null,"Cell Death and Survival","apoptosis","apoptosis of neurons","1,32E-03","ELAVL4, FOXO3, LMX1B, MAP2K5, PARK2, RPTOR","6"]
[null,"Cell Death and Survival","apoptosis","apoptosis of Langerhans cells","4,41E-03","RPTOR","1"]
[null,"Cell Death and Survival","apoptosis","apoptosis of MCTC mast cell","4,41E-03","FOXO3","1"]
[null,"Cell Death and Survival","apoptosis","apoptosis of mucosal mast cells","4,41E-03","FOXO3","1"]
[null,"Cell Death and Survival","apoptosis","apoptosis of spermatids","8,80E-03","HIP1","1"]
[null,"Cell Death and Survival","apoptosis","apoptosis of gonadal cells","9,90E-03","ETV5, FOXO3, HIP1","3"]
[null,"Cell Death and Survival","apoptosis","apoptosis of medulloblastoma cells","1,10E-02","MAP2K5","1"]
[null,"Cell Death and Survival","apoptosis","apoptosis of dopaminergic neurons","1,75E-02","PARK2","1"]
[null,"Cell Death and Survival","apoptosis","apoptosis of male germ cells","3,02E-02","ETV5, HIP1","2"]
[null,"Cell Death and Survival","apoptosis","apoptosis of brain cancer cell lines","3,39E-02","FOXO3, MAP2K5","2"]
[null,"Cell Death and Survival","apoptosis","apoptosis of neuroblastoma cell lines","3,39E-02","FOXO3, PARK2","2"]
[null,"Cell Death and Survival","apoptosis","apoptosis of cerebellar granule cell","4,11E-02","MAP2K5","1"]
[null,"Cell Death and Survival","apoptosis","apoptosis of embryoblast","4,33E-02","KAT8","1"]
[null,"Cell Death and Survival","loss","loss of dopaminergic neurons","1,38E-03","LMX1B, PARK2","2"]
[null,"Cell Death and Survival","loss","loss of Langerhans cells","4,41E-03","RPTOR","1"]
[null,"Cell Death and Survival","loss","loss of neuronal progenitor cells","6,61E-03","FOXO3","1"]
[null,"Cell Death and Survival","degradation","degradation of bacteria","8,80E-03","SCARB2","1"]
[null,"Cell Death and Survival","cell viability","cell viability of B-lymphocyte derived cell lines","8,81E-03","MAP2K5, TAL1","2"]
[null,"Cell Death and Survival","cell viability","cell viability of mesothelioma cell lines","2,62E-02","MAP2K5","1"]
[null,"Cell Death and Survival","cell viability","cell viability of vascular smooth muscle cells","2,83E-02","FOXO3","1"]
[null,"Cell Death and Survival","survival","survival of erythroid cells","1,10E-02","TAL1","1"]
[null,"Cell Death and Survival","self-renewal","self-renewal of myeloid progenitor cells","1,32E-02","FOXO3","1"]
[null,"Cell Death and Survival","degeneration","degeneration of neurons","2,61E-02","GRID1, PARK2, SCARB2","3"]
[null,"Cell Death and Survival","atrophy","atrophy of myofiber","3,48E-02","FOXO3","1"]
[4,"Neurological Disease","cell death","cell death of granule cells","3,52E-05","FOXO3, KCNK3, MAP2K5, PARK2","4"]
[null,"Neurological Disease","cell death","cell death of brain cells","7,46E-04","FOXO3, HIP1, KCNK3, MAP2K5, PARK2","5"]
[null,"Neurological Disease","cell death","cell death of hippocampal neurons","1,55E-02","FOXO3, KCNK3","2"]
[null,"Neurological Disease","cell death","cell death of cerebral cortex cells","2,13E-02","FOXO3, HIP1, KCNK3","3"]
[null,"Neurological Disease","neurodegeneration","neurodegeneration of dopaminergic neurons","1,28E-03","PARK2, SCARB2","2"]
[null,"Neurological Disease","neurodegeneration","neurodegeneration of outer hair cells","2,41E-03","GRID1, SCARB2","2"]
[null,"Neurological Disease","neurodegeneration","neurodegeneration of hippocampal neurons","3,69E-02","PARK2","1"]
[null,"Neurological Disease","adult polyglucosan body disease","adult polyglucosan body disease","2,21E-03","GBE1","1"]
[null,"Neurological Disease","autosomal recessive juvenile Parkinson disease type 2","autosomal recessive juvenile Parkinson disease type 2","2,21E-03","PARK2","1"]
[null,"Neurological Disease","autosomal recessive spastic paraplegia type 45","autosomal recessive spastic paraplegia type 45","2,21E-03","NT5C2","1"]
[null,"Neurological Disease","progressive myoclonic epilepsy type 4 without renal failure","progressive myoclonic epilepsy type 4 without renal failure","2,21E-03","SCARB2","1"]
[null,"Neurological Disease","tremor","tremor of body trunk","2,21E-03","PARK2","1"]
[null,"Neurological Disease","tremor","tremor","5,67E-03","HIP1, PARK2, SCARB2","3"]
[null,"Neurological Disease","tremor","tremor of limb","1,10E-02","PARK2","1"]
[null,"Neurological Disease","progressive myoclonic epilepsy type 4 with renal failure","progressive myoclonic epilepsy type 4 with renal failure","4,41E-03","SCARB2","1"]
[null,"Neurological Disease","mental retardation","severe mental retardation","6,61E-03","TCF7L2","1"]
[null,"Neurological Disease","motor dysfunction","progressive motor dysfunction","8,80E-03","PARK2","1"]
[null,"Neurological Disease","pervasive developmental disorder","pervasive developmental disorder","1,29E-02","EHBP1, MAP2K5, TCF7L2","3"]
[null,"Neurological Disease","movement disorder","Movement Disorders","1,42E-02","ETV5, FOXO3, GNAT2, HIP1, MAP2K5, PARK2, SCARB2, USP37","8"]
[null,"Neurological Disease","cerebral edema","cerebral edema","1,75E-02","FOXO3","1"]
[null,"Neurological Disease","sensorimotor impairment","sensorimotor impairment","1,75E-02","PARK2","1"]
[null,"Neurological Disease","Parkinson's disease","autosomal dominant Parkinson's disease","1,97E-02","PARK2","1"]
[null,"Neurological Disease","Parkinson's disease","Parkinson's disease","2,84E-02","PARK2, SCARB2, USP37","3"]
[null,"Neurological Disease","noise-induced hearing loss","noise-induced hearing loss","2,19E-02","GRID1","1"]
[null,"Neurological Disease","encephalopathy","autosomal dominant encephalopathy","2,37E-02","GNAT2, PARK2","2"]
[null,"Neurological Disease","disorder of basal ganglia","disorder of basal ganglia","2,44E-02","ETV5, FOXO3, GNAT2, PARK2, SCARB2, USP37","6"]
[null,"Neurological Disease","degeneration","degeneration of neurons","2,61E-02","GRID1, PARK2, SCARB2","3"]
[null,"Neurological Disease","bipolar disorder","bipolar disorder","2,97E-02","GRID1, LINC00907, TOMM40","3"]
[null,"Neurological Disease","dyskinesia","dyskinesia","3,17E-02","ETV5, FOXO3, GNAT2, PARK2, SCARB2","5"]
[null,"Neurological Disease","late-onset Parkinson disease","late-onset Parkinson disease","3,48E-02","PARK2","1"]
[null,"Neurological Disease","apoptosis","apoptosis of cerebellar granule cell","4,11E-02","MAP2K5","1"]
[null,"Neurological Disease","spinocerebellar disease","spinocerebellar disease","4,44E-02","GNAT2, NT5C2","2"]
[5,"Cell-To-Cell Signaling and Interaction","endocochlear potential","endocochlear potential","9,94E-05","GRID1, SCARB2","2"]
[null,"Cell-To-Cell Signaling and Interaction","auditory evoked potential","abnormal auditory evoked potential","3,10E-04","GRID1, SCARB2","2"]
[null,"Cell-To-Cell Signaling and Interaction","aggregation","aggregation of hepatoma cell lines","2,21E-03","TCF7L2","1"]
[null,"Cell-To-Cell Signaling and Interaction","aggregation","aggregation of carcinoma cell lines","1,54E-02","TCF7L2","1"]
[null,"Cell-To-Cell Signaling and Interaction","hyperactivation","hyperactivation of helper T lymphocytes","2,21E-03","FOXO3","1"]
[null,"Cell-To-Cell Signaling and Interaction","adhesion","adhesion of endometrial cancer cell lines","4,41E-03","ETV5","1"]
[null,"Cell-To-Cell Signaling and Interaction","excitation","excitation of striatal neurons","4,41E-03","PARK2","1"]
[null,"Cell-To-Cell Signaling and Interaction","cell-cell contact","cell-cell contact of colorectal cancer cell lines","6,61E-03","RPTOR","1"]
[null,"Cell-To-Cell Signaling and Interaction","neurotransmission","neurotransmission of synapse","7,28E-03","ETV5, PARK2","2"]
[null,"Cell-To-Cell Signaling and Interaction","reorganization","reorganization of cell-cell contacts","1,10E-02","ETV5","1"]
[null,"Cell-To-Cell Signaling and Interaction","catabolism","catabolism of dopamine","1,32E-02","PARK2","1"]
[null,"Cell-To-Cell Signaling and Interaction","long term depression","long term depression of hippocampal neurons","1,54E-02","HIP1","1"]
[null,"Cell-To-Cell Signaling and Interaction","metabolism","metabolism of norepinephrine","2,40E-02","PARK2","1"]
[null,"Cell-To-Cell Signaling and Interaction","suppressive capacity","suppressive capacity of TREG cells","2,40E-02","RPTOR","1"]
[null,"Cell-To-Cell Signaling and Interaction","phagocytosis","phagocytosis of macrophage cancer cell lines","2,62E-02","CLIP1","1"]
[null,"Cell-To-Cell Signaling and Interaction","contact growth inhibition","contact growth inhibition of colorectal cancer cell lines","3,05E-02","FOXO3","1"]
[null,"Cell-To-Cell Signaling and Interaction","abnormal quantity","abnormal quantity of dopamine","3,26E-02","PARK2","1"]
[null,"Cell-To-Cell Signaling and Interaction","cell-cell adhesion","cell-cell adhesion of neurons","3,26E-02","NRXN3","1"]
[null,"Cell-To-Cell Signaling and Interaction","synaptic transmission","synaptic transmission of neuromuscular synapse","4,11E-02","ETV5","1"]
[6,"Nervous System Development and Function","endocochlear potential","endocochlear potential","9,94E-05","GRID1, SCARB2","2"]
[null,"Nervous System Development and Function","auditory evoked potential","abnormal auditory evoked potential","3,10E-04","GRID1, SCARB2","2"]
[null,"Nervous System Development and Function","size","size of mesencephalon","4,26E-04","FTO, LMX1B","2"]
[null,"Nervous System Development and Function","size","size of interneurons","4,41E-03","GRID1","1"]
[null,"Nervous System Development and Function","size","size of superior colliculus","4,41E-03","LMX1B","1"]
[null,"Nervous System Development and Function","size","size of olfactory bulb","1,10E-02","FOXO3","1"]
[null,"Nervous System Development and Function","size","size of pallium","1,32E-02","FTO","1"]
[null,"Nervous System Development and Function","size","size of dentate gyrus","1,54E-02","FOXO3","1"]
[null,"Nervous System Development and Function","loss","loss of dopaminergic neurons","1,38E-03","LMX1B, PARK2","2"]
[null,"Nervous System Development and Function","abnormal morphology","abnormal morphology of enlarged adenohypophysis","2,21E-03","TCF7L2","1"]
[null,"Nervous System Development and Function","abnormal morphology","abnormal morphology of mesencephalon","4,25E-03","LMX1B, PARK2","2"]
[null,"Nervous System Development and Function","abnormal morphology","abnormal morphology of locus ceruleus","8,80E-03","PARK2","1"]
[null,"Nervous System Development and Function","abnormal morphology","abnormal morphology of pretectum","8,80E-03","LMX1B","1"]
[null,"Nervous System Development and Function","abnormal morphology","abnormal morphology of dopaminergic neurons","1,10E-02","LMX1B","1"]
[null,"Nervous System Development and Function","abnormal morphology","abnormal morphology of neuroglia","1,62E-02","PARK2, SCARB2","2"]
[null,"Nervous System Development and Function","abnormal morphology","abnormal morphology of superior colliculus","1,75E-02","LMX1B","1"]
[null,"Nervous System Development and Function","abnormal morphology","abnormal morphology of substantia nigra","1,97E-02","PARK2","1"]
[null,"Nervous System Development and Function","abnormal morphology","abnormal morphology of phrenic nerve","3,48E-02","SCARB2","1"]
[null,"Nervous System Development and Function","abnormal morphology","abnormal morphology of Schwann cells","3,69E-02","SCARB2","1"]
[null,"Nervous System Development and Function","specification","specification of primary neurons","2,21E-03","ELAVL4","1"]
[null,"Nervous System Development and Function","axonal transport","arrest in axonal transport of mitochondria","4,41E-03","PARK2","1"]
[null,"Nervous System Development and Function","excitation","excitation of striatal neurons","4,41E-03","PARK2","1"]
[null,"Nervous System Development and Function","quantity","quantity of catecholaminergic neurons","4,41E-03","PARK2","1"]
[null,"Nervous System Development and Function","differentiation","differentiation of neurons","5,69E-03","ELAVL4, ETV5, FOXO3, LMX1B, TAL1","5"]
[null,"Nervous System Development and Function","differentiation","differentiation of dorsal root ganglion cells","6,61E-03","ETV5","1"]
[null,"Nervous System Development and Function","function","function of vestibular hair cells","6,61E-03","SCARB2","1"]
[null,"Nervous System Development and Function","neurotransmission","neurotransmission of synapse","7,28E-03","ETV5, PARK2","2"]
[null,"Nervous System Development and Function","proliferation","proliferation of satellite cells","8,80E-03","FOXO3","1"]
[null,"Nervous System Development and Function","morphology","morphology of brain","1,01E-02","FTO, GRID1, LMX1B, PARK2, TCF7L2","5"]
[null,"Nervous System Development and Function","morphology","morphology of cerebral cortex","1,47E-02","GRID1, LMX1B, PARK2","3"]
[null,"Nervous System Development and Function","morphology","morphology of nervous system","3,28E-02","FTO, GRID1, LMX1B, PARK2, SCARB2, TCF7L2","6"]
[null,"Nervous System Development and Function","morphogenesis","morphogenesis of brain","1,13E-02","FTO, LMX1B","2"]
[null,"Nervous System Development and Function","morphogenesis","morphogenesis of cerebellum","3,48E-02","LMX1B","1"]
[null,"Nervous System Development and Function","development","development of midbrain-hindbrain boundary","1,32E-02","LMX1B","1"]
[null,"Nervous System Development and Function","development","development of central nervous system","4,04E-02","FOXO3, FTO, LMX1B, PARK2, TCF7L2","5"]
[null,"Nervous System Development and Function","expansion","expansion of motor neurons","1,32E-02","FTO","1"]
[null,"Nervous System Development and Function","generation","generation of v3 neuron","1,32E-02","FTO","1"]
[null,"Nervous System Development and Function","long term depression","long term depression of hippocampal neurons","1,54E-02","HIP1","1"]
[null,"Nervous System Development and Function","sensorimotor integration","sensorimotor integration","1,54E-02","PARK2","1"]
[null,"Nervous System Development and Function","cell-cell adhesion","cell-cell adhesion of neurons","3,26E-02","NRXN3","1"]
[null,"Nervous System Development and Function","synaptic transmission","synaptic transmission of neuromuscular synapse","4,11E-02","ETV5","1"]
[7,"Cell Cycle","G1/S phase transition","G1/S phase transition of leukocytes","2,12E-04","RPTOR, TAL1","2"]
[null,"Cell Cycle","G1/S phase transition","G1/S phase transition of DN1 cells","2,21E-03","RPTOR","1"]
[null,"Cell Cycle","G1/S phase transition","G1/S phase transition of macrophages","4,41E-03","TAL1","1"]
[null,"Cell Cycle","G1/S phase transition","G1/S phase transition","1,79E-02","RPTOR, TAL1, USP37","3"]
[null,"Cell Cycle","cell cycle progression","arrest in cell cycle progression of breast cancer cell lines","1,74E-03","FOXO3, PARK2","2"]
[null,"Cell Cycle","cell cycle progression","cell cycle progression of hematopoietic progenitor cells","2,71E-03","RPTOR, TAL1","2"]
[null,"Cell Cycle","cell cycle progression","delay in cell cycle progression","2,71E-03","CLIP1, FOXO3","2"]
[null,"Cell Cycle","cell cycle progression","cell cycle progression of double-negative T lymphocyte","4,41E-03","RPTOR","1"]
[null,"Cell Cycle","cell cycle progression","cell cycle progression of promegakaryocytes","4,41E-03","TAL1","1"]
[null,"Cell Cycle","cell cycle progression","re-entry into cell cycle progression of lung cell lines","6,61E-03","FOXO3","1"]
[null,"Cell Cycle","cell cycle progression","arrest in cell cycle progression of squamous cell carcinoma cell lines","8,80E-03","FOXO3","1"]
[null,"Cell Cycle","cell cycle progression","arrest in cell cycle progression of leukemia cells","1,10E-02","RPTOR","1"]
[null,"Cell Cycle","cell cycle progression","arrest in cell cycle progression","1,38E-02","FOXO3, PARK2, RPTOR, TCF7L2","4"]
[null,"Cell Cycle","cell cycle progression","cell cycle progression","3,83E-02","CLIP1, FOXO3, KAT8, PARK2, RPTOR, TAL1, TCF7L2","7"]
[null,"Cell Cycle","mitosis","arrest in mitosis of erythroid cells","2,21E-03","FOXO3","1"]
[null,"Cell Cycle","mitosis","arrest in mitosis of embryonic cell lines","6,61E-03","CLIP1","1"]
[null,"Cell Cycle","mitosis","arrest in mitosis of epithelial cell lines","6,61E-03","CLIP1","1"]
[null,"Cell Cycle","mitosis","arrest in mitosis of kidney cell lines","6,61E-03","CLIP1","1"]
[null,"Cell Cycle","mitosis","arrest in mitosis","1,76E-02","CLIP1, FOXO3","2"]
[null,"Cell Cycle","polyploidization","polyploidization of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Cell Cycle","interphase","interphase","2,93E-03","CALCR, FOXO3, MTCH2, PARK2, RPTOR, TAL1, USP37","7"]
[null,"Cell Cycle","interphase","arrest in interphase","3,02E-02","CALCR, FOXO3, MTCH2, PARK2","4"]
[null,"Cell Cycle","interphase","arrest in interphase of tumor cell lines","3,43E-02","FOXO3, MTCH2, PARK2","3"]
[null,"Cell Cycle","fission","fission","3,88E-03","PARK2, RPTOR","2"]
[null,"Cell Cycle","S phase","arrest in S phase of adenocarcinoma cell lines","4,41E-03","MTCH2","1"]
[null,"Cell Cycle","S phase","exit from S phase of colorectal cancer cell lines","1,54E-02","FOXO3","1"]
[null,"Cell Cycle","S phase","entry into S phase of leukocytes","3,05E-02","TAL1","1"]
[null,"Cell Cycle","S phase","S phase","3,25E-02","FOXO3, MTCH2, TAL1","3"]
[null,"Cell Cycle","S phase","S phase of tumor cell lines","3,73E-02","FOXO3, MTCH2","2"]
[null,"Cell Cycle","cell division","cell division of male germ cells","6,61E-03","ETV5","1"]
[null,"Cell Cycle","G0/G1 phase transition","arrest in G0/G1 phase transition of leukemia cell lines","8,80E-03","FOXO3","1"]
[null,"Cell Cycle","mitochondrial fission","mitochondrial fission of cervical cancer cell lines","1,10E-02","PARK2","1"]
[null,"Cell Cycle","G1 phase","arrest in G1 phase of brain cancer cell lines","2,19E-02","PARK2","1"]
[null,"Cell Cycle","G1 phase","G1 phase","2,32E-02","PARK2, RPTOR, TAL1, USP37","4"]
[null,"Cell Cycle","G1 phase","entry into G1 phase","3,05E-02","TAL1","1"]
[null,"Cell Cycle","G2 phase","arrest in G2 phase of kidney cell lines","2,40E-02","CALCR","1"]
[null,"Cell Cycle","G2 phase","arrest in G2 phase of embryonic cell lines","2,62E-02","CALCR","1"]
[null,"Cell Cycle","G2 phase","arrest in G2 phase of epithelial cell lines","2,83E-02","CALCR","1"]
[null,"Cell Cycle","contact growth inhibition","contact growth inhibition of colorectal cancer cell lines","3,05E-02","FOXO3","1"]
[8,"Cell Morphology","size","size of cells","2,19E-04","FOXO3, FTO, GRID1, MAP2K5, RPTOR, SCARB2, TCF7L2","7"]
[null,"Cell Morphology","size","size of Langerhans cells","2,21E-03","RPTOR","1"]
[null,"Cell Morphology","size","size of interneurons","4,41E-03","GRID1","1"]
[null,"Cell Morphology","size","size of muscle cells","3,78E-02","FOXO3, SCARB2","2"]
[null,"Cell Morphology","lack","lack of myeloid progenitor cells","2,59E-04","HIP1, TAL1","2"]
[null,"Cell Morphology","lack","lack of podocyte slit diaphragm","1,10E-02","LMX1B","1"]
[null,"Cell Morphology","lack","lack of pedicels","1,32E-02","LMX1B","1"]
[null,"Cell Morphology","area","area of cells","3,82E-04","MAP2K5, SCARB2, TCF7L2","3"]
[null,"Cell Morphology","area","area of vascular endothelial cells","2,21E-03","MAP2K5","1"]
[null,"Cell Morphology","area","area of beta islet cells","8,80E-03","TCF7L2","1"]
[null,"Cell Morphology","polarization","polarization of lung cancer cell lines","2,21E-03","CLIP1","1"]
[null,"Cell Morphology","polarization","polarization of carcinoma cell lines","4,41E-03","CLIP1","1"]
[null,"Cell Morphology","swelling","delay in swelling of mitochondria","2,21E-03","PARK2","1"]
[null,"Cell Morphology","morphology","morphology of hematopoietic progenitor cells","5,67E-03","FOXO3, HIP1, TAL1","3"]
[null,"Cell Morphology","morphology","morphology of cells","5,83E-03","ETV5, FOXO3, FTO, GRID1, HIP1, KAT8, LMX1B, MAP2K5, PARK2, RPTOR, SCARB2, TAL1, TCF7L2","13"]
[null,"Cell Morphology","morphology","morphology of breast cell lines","4,33E-02","FOXO3","1"]
[null,"Cell Morphology","autophagy","autophagy","6,45E-03","FOXO3, KAT8, LMX1B, PARK2, RPTOR","5"]
[null,"Cell Morphology","autophagy","autophagy of cortical neurons","1,10E-02","PARK2","1"]
[null,"Cell Morphology","autophagy","autophagy of heart","1,54E-02","PARK2","1"]
[null,"Cell Morphology","autophagy","autophagy of muscle","1,54E-02","FOXO3","1"]
[null,"Cell Morphology","autophagy","autophagy of neuroblastoma cell lines","1,75E-02","RPTOR","1"]
[null,"Cell Morphology","autophagy","autophagy of mitochondria","1,97E-02","PARK2","1"]
[null,"Cell Morphology","autophagy","autophagy of fibroblasts","3,69E-02","FOXO3","1"]
[null,"Cell Morphology","autophagy","autophagy of cells","4,02E-02","FOXO3, PARK2, RPTOR","3"]
[null,"Cell Morphology","cell spreading","cell spreading of macrophage cancer cell lines","8,80E-03","CLIP1","1"]
[null,"Cell Morphology","orientation","orientation of microtubules","8,80E-03","CLIP1","1"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of germ cells","9,24E-03","ETV5, FOXO3, HIP1","3"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of dopaminergic neurons","1,10E-02","LMX1B","1"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of marginal stria vascularis cells","1,54E-02","SCARB2","1"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of pedicels","1,54E-02","LMX1B","1"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of neuroglia","1,62E-02","PARK2, SCARB2","2"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of enterocytes","2,62E-02","TCF7L2","1"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of natural killer cells","2,62E-02","FOXO3","1"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of male germ cells","2,89E-02","ETV5, HIP1","2"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of Schwann cells","3,69E-02","SCARB2","1"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of cells","3,90E-02","ETV5, FOXO3, HIP1, KAT8, LMX1B, PARK2, SCARB2, TCF7L2","8"]
[null,"Cell Morphology","abnormal morphology","abnormal morphology of spermatogonia","4,54E-02","ETV5","1"]
[null,"Cell Morphology","reorganization","reorganization of cell-cell contacts","1,10E-02","ETV5","1"]
[null,"Cell Morphology","length","length of cilia","1,32E-02","FTO","1"]
[null,"Cell Morphology","elongation","elongation of cardiomyocytes","1,54E-02","MAP2K5","1"]
[null,"Cell Morphology","elongation","elongation of mitochondria","1,75E-02","PARK2","1"]
[9,"Hematological System Development and Function","lack","lack of myeloid progenitor cells","2,59E-04","HIP1, TAL1","2"]
[null,"Hematological System Development and Function","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Hematological System Development and Function","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Hematological System Development and Function","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Hematological System Development and Function","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Hematological System Development and Function","development","development of mast cells","1,32E-02","TAL1","1"]
[null,"Hematological System Development and Function","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[null,"Hematological System Development and Function","development","development of follicular B lymphocytes","4,54E-02","TAL1","1"]
[null,"Hematological System Development and Function","cell proliferation","cell proliferation of leukocyte cell lines","1,75E-03","HIP1, MAP2K5, RABEP1, TAL1","4"]
[null,"Hematological System Development and Function","accumulation","accumulation of memory precursor T lymphocytes","2,21E-03","FOXO3","1"]
[null,"Hematological System Development and Function","accumulation","accumulation of T lymphocytes","2,63E-02","FOXO3, TAL1","2"]
[null,"Hematological System Development and Function","hyperactivation","hyperactivation of helper T lymphocytes","2,21E-03","FOXO3","1"]
[null,"Hematological System Development and Function","maturation","maturation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Hematological System Development and Function","maturation","maturation of red blood cells","2,27E-03","FOXO3, TAL1","2"]
[null,"Hematological System Development and Function","maturation","maturation of marginal-zone B lymphocytes","6,61E-03","TAL1","1"]
[null,"Hematological System Development and Function","maturation","maturation of hematopoietic progenitor cells","1,38E-02","FOXO3, TAL1","2"]
[null,"Hematological System Development and Function","maturation","maturation of erythroid cells","3,48E-02","FOXO3","1"]
[null,"Hematological System Development and Function","proliferation","proliferation of bone-marrow-derived monocyte/macrophage precursor cells","2,21E-03","TAL1","1"]
[null,"Hematological System Development and Function","proliferation","proliferation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Hematological System Development and Function","proliferation","proliferation of TREG cells","4,33E-02","RPTOR","1"]
[null,"Hematological System Development and Function","quantity","quantity of spleen-derived dendritic cells","2,21E-03","RPTOR","1"]
[null,"Hematological System Development and Function","quantity","quantity of mast precursor cells","4,41E-03","TAL1","1"]
[null,"Hematological System Development and Function","quantity","quantity of memory T lymphocytes","1,10E-02","FOXO3, RPTOR","2"]
[null,"Hematological System Development and Function","quantity","quantity of megakaryocyte/erythrocyte lineage-restricted progenitor cells","1,54E-02","TAL1","1"]
[null,"Hematological System Development and Function","differentiation","differentiation of B-2 lymphocytes","6,61E-03","TAL1","1"]
[null,"Hematological System Development and Function","differentiation","differentiation of marginal-zone B lymphocytes","6,61E-03","TAL1","1"]
[null,"Hematological System Development and Function","differentiation","differentiation of transitional 1 B lymphocytes","6,61E-03","TAL1","1"]
[null,"Hematological System Development and Function","differentiation","differentiation of bone-marrow-derived monocyte/macrophage precursor cells","2,83E-02","TAL1","1"]
[null,"Hematological System Development and Function","cell viability","cell viability of B-lymphocyte derived cell lines","8,81E-03","MAP2K5, TAL1","2"]
[null,"Hematological System Development and Function","production","production of follicular B lymphocytes","1,10E-02","TAL1","1"]
[null,"Hematological System Development and Function","survival","survival of erythroid cells","1,10E-02","TAL1","1"]
[null,"Hematological System Development and Function","commitment","commitment of B lymphocytes","1,32E-02","TAL1","1"]
[null,"Hematological System Development and Function","expansion","expansion of effector T lymphocytes","1,32E-02","FOXO3","1"]
[null,"Hematological System Development and Function","self-renewal","self-renewal of myeloid progenitor cells","1,32E-02","FOXO3","1"]
[null,"Hematological System Development and Function","suppressive capacity","suppressive capacity of TREG cells","2,40E-02","RPTOR","1"]
[null,"Hematological System Development and Function","colony formation","colony formation of erythroid cells","2,62E-02","TAL1","1"]
[null,"Hematological System Development and Function","colony formation","colony formation of megakaryocytes","3,69E-02","TAL1","1"]
[null,"Hematological System Development and Function","migration","migration of Langerhans cells","4,33E-02","RPTOR","1"]
[10,"Hematopoiesis","lack","lack of myeloid progenitor cells","2,59E-04","HIP1, TAL1","2"]
[null,"Hematopoiesis","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Hematopoiesis","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Hematopoiesis","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Hematopoiesis","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Hematopoiesis","development","development of mast cells","1,32E-02","TAL1","1"]
[null,"Hematopoiesis","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[null,"Hematopoiesis","development","development of follicular B lymphocytes","4,54E-02","TAL1","1"]
[null,"Hematopoiesis","maturation","maturation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Hematopoiesis","maturation","maturation of red blood cells","2,27E-03","FOXO3, TAL1","2"]
[null,"Hematopoiesis","maturation","maturation of marginal-zone B lymphocytes","6,61E-03","TAL1","1"]
[null,"Hematopoiesis","maturation","maturation of hematopoietic progenitor cells","1,38E-02","FOXO3, TAL1","2"]
[null,"Hematopoiesis","maturation","maturation of erythroid cells","3,48E-02","FOXO3","1"]
[null,"Hematopoiesis","maturation","maturation of leukemia cell lines","3,69E-02","FOXO3","1"]
[null,"Hematopoiesis","mitosis","arrest in mitosis of erythroid cells","2,21E-03","FOXO3","1"]
[null,"Hematopoiesis","proliferation","proliferation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Hematopoiesis","quantity","quantity of mast precursor cells","4,41E-03","TAL1","1"]
[null,"Hematopoiesis","quantity","quantity of megakaryocyte/erythrocyte lineage-restricted progenitor cells","1,54E-02","TAL1","1"]
[null,"Hematopoiesis","morphology","morphology of hematopoietic progenitor cells","5,67E-03","FOXO3, HIP1, TAL1","3"]
[null,"Hematopoiesis","differentiation","differentiation of B-2 lymphocytes","6,61E-03","TAL1","1"]
[null,"Hematopoiesis","differentiation","differentiation of marginal-zone B lymphocytes","6,61E-03","TAL1","1"]
[null,"Hematopoiesis","differentiation","differentiation of transitional 1 B lymphocytes","6,61E-03","TAL1","1"]
[null,"Hematopoiesis","differentiation","differentiation of bone-marrow-derived monocyte/macrophage precursor cells","2,83E-02","TAL1","1"]
[null,"Hematopoiesis","commitment","commitment of B lymphocytes","1,32E-02","TAL1","1"]
[null,"Hematopoiesis","self-renewal","self-renewal of myeloid progenitor cells","1,32E-02","FOXO3","1"]
[null,"Hematopoiesis","colony formation","colony formation of erythroid cells","2,62E-02","TAL1","1"]
[null,"Hematopoiesis","colony formation","colony formation of megakaryocytes","3,69E-02","TAL1","1"]
[11,"Lymphoid Tissue Structure and Development","lack","lack of myeloid progenitor cells","2,59E-04","HIP1, TAL1","2"]
[null,"Lymphoid Tissue Structure and Development","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Lymphoid Tissue Structure and Development","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Lymphoid Tissue Structure and Development","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Lymphoid Tissue Structure and Development","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Lymphoid Tissue Structure and Development","development","development of mast cells","1,32E-02","TAL1","1"]
[null,"Lymphoid Tissue Structure and Development","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[null,"Lymphoid Tissue Structure and Development","development","development of follicular B lymphocytes","4,54E-02","TAL1","1"]
[null,"Lymphoid Tissue Structure and Development","proliferation","proliferation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Lymphoid Tissue Structure and Development","quantity","quantity of megakaryocyte/erythrocyte lineage-restricted progenitor cells","1,54E-02","TAL1","1"]
[12,"Tissue Morphology","lack","lack of myeloid progenitor cells","2,59E-04","HIP1, TAL1","2"]
[null,"Tissue Morphology","lack","lack of blood island","2,62E-02","TAL1","1"]
[null,"Tissue Morphology","lack","lack of chorion","2,83E-02","MTCH2","1"]
[null,"Tissue Morphology","lack","lack of amnion","3,90E-02","MTCH2","1"]
[null,"Tissue Morphology","quantity","quantity of tumor","3,33E-04","HHIP, HIP1, PARK2, TAL1","4"]
[null,"Tissue Morphology","quantity","quantity of basal-cell carcinoma","2,21E-03","HHIP","1"]
[null,"Tissue Morphology","quantity","quantity of pedicels","2,21E-03","LMX1B","1"]
[null,"Tissue Morphology","quantity","quantity of spleen-derived dendritic cells","2,21E-03","RPTOR","1"]
[null,"Tissue Morphology","quantity","quantity of type IV fibrocyte","2,21E-03","GRID1","1"]
[null,"Tissue Morphology","quantity","quantity of catecholaminergic neurons","4,41E-03","PARK2","1"]
[null,"Tissue Morphology","quantity","quantity of fenestra","4,41E-03","LMX1B","1"]
[null,"Tissue Morphology","quantity","quantity of mast precursor cells","4,41E-03","TAL1","1"]
[null,"Tissue Morphology","quantity","quantity of podocyte slit diaphragm","4,41E-03","LMX1B","1"]
[null,"Tissue Morphology","quantity","quantity of adenomatous polyps","6,61E-03","PARK2","1"]
[null,"Tissue Morphology","quantity","quantity of carcinoma cells","6,61E-03","FOXO3","1"]
[null,"Tissue Morphology","quantity","quantity of enterocytes","6,61E-03","TCF7L2","1"]
[null,"Tissue Morphology","quantity","quantity of memory T lymphocytes","1,10E-02","FOXO3, RPTOR","2"]
[null,"Tissue Morphology","quantity","quantity of malignant tumor","1,22E-02","HHIP, TAL1","2"]
[null,"Tissue Morphology","quantity","quantity of megakaryocyte/erythrocyte lineage-restricted progenitor cells","1,54E-02","TAL1","1"]
[null,"Tissue Morphology","quantity","quantity of lymphoma","3,90E-02","TAL1","1"]
[null,"Tissue Morphology","neurodegeneration","neurodegeneration of dopaminergic neurons","1,28E-03","PARK2, SCARB2","2"]
[null,"Tissue Morphology","neurodegeneration","neurodegeneration of outer hair cells","2,41E-03","GRID1, SCARB2","2"]
[null,"Tissue Morphology","neurodegeneration","neurodegeneration of hippocampal neurons","3,69E-02","PARK2","1"]
[null,"Tissue Morphology","loss","loss of dopaminergic neurons","1,38E-03","LMX1B, PARK2","2"]
[null,"Tissue Morphology","area","area of vascular endothelial cells","2,21E-03","MAP2K5","1"]
[null,"Tissue Morphology","outgrowth","outgrowth of glomerular capillary","2,21E-03","LMX1B","1"]
[null,"Tissue Morphology","remodeling","remodeling of vitelline artery","2,21E-03","TAL1","1"]
[null,"Tissue Morphology","cleavage","cleavage of glomerular basement membrane","4,41E-03","LMX1B","1"]
[null,"Tissue Morphology","size","size of interneurons","4,41E-03","GRID1","1"]
[null,"Tissue Morphology","size","size of olfactory bulb","1,10E-02","FOXO3","1"]
[null,"Tissue Morphology","size","size of muscle cells","3,78E-02","FOXO3, SCARB2","2"]
[null,"Tissue Morphology","abnormal morphology","abnormal morphology of iris stroma","8,80E-03","LMX1B","1"]
[null,"Tissue Morphology","abnormal morphology","abnormal morphology of dopaminergic neurons","1,10E-02","LMX1B","1"]
[null,"Tissue Morphology","abnormal morphology","abnormal morphology of urothelium","1,54E-02","SCARB2","1"]
[null,"Tissue Morphology","abnormal morphology","abnormal morphology of lens epithelium","3,26E-02","LMX1B","1"]
[null,"Tissue Morphology","abnormal morphology","abnormal morphology of corneal stroma","3,90E-02","LMX1B","1"]
[null,"Tissue Morphology","abnormal morphology","abnormal morphology of interparietal bone","4,54E-02","LMX1B","1"]
[null,"Tissue Morphology","degeneration","degeneration of floor plate","1,32E-02","FTO","1"]
[null,"Tissue Morphology","degeneration","degeneration of type IV fibrocyte","1,32E-02","GRID1","1"]
[null,"Tissue Morphology","degeneration","degeneration of connective tissue","2,13E-02","GRID1, SLC39A8","2"]
[null,"Tissue Morphology","degeneration","degeneration of neurons","2,61E-02","GRID1, PARK2, SCARB2","3"]
[null,"Tissue Morphology","morphology","morphology of endothelial tissue","1,48E-02","LMX1B, MAP2K5","2"]
[null,"Tissue Morphology","thickness","thickness of basement membrane","3,48E-02","LMX1B","1"]
[null,"Tissue Morphology","erosion","erosion of articular cartilage","3,69E-02","SLC39A8","1"]
[13,"Cancer","quantity","quantity of tumor","3,33E-04","HHIP, HIP1, PARK2, TAL1","4"]
[null,"Cancer","quantity","quantity of basal-cell carcinoma","2,21E-03","HHIP","1"]
[null,"Cancer","quantity","quantity of adenomatous polyps","6,61E-03","PARK2","1"]
[null,"Cancer","quantity","quantity of carcinoma cells","6,61E-03","FOXO3","1"]
[null,"Cancer","quantity","quantity of malignant tumor","1,22E-02","HHIP, TAL1","2"]
[null,"Cancer","quantity","quantity of lymphoma","3,90E-02","TAL1","1"]
[null,"Cancer","hemangioma","hemangioma","4,16E-04","CADM2, FOXO3, HIP1, NRXN3, PARK2, RPTOR","6"]
[null,"Cancer","hemangioblastoma","hemangioblastoma","1,10E-03","CADM2, FOXO3, HIP1, PARK2, RPTOR","5"]
[null,"Cancer","precursor T-cell lymphoblastic leukemia-lymphoma","precursor T-cell lymphoblastic leukemia-lymphoma","1,32E-03","NT5C2, RPTOR, TAL1","3"]
[null,"Cancer","hereditary prostate cancer 12","hereditary prostate cancer 12","2,21E-03","EHBP1","1"]
[null,"Cancer","acute lymphocytic leukemia","acute lymphocytic leukemia","2,39E-03","FOXO3, NT5C2, RPTOR, TAL1","4"]
[null,"Cancer","skin cancer","skin cancer","4,18E-03","ASB4, CADM2, CALCR, CLIP1, DMXL2, EHBP1, ELAVL4, FOXO3, GNAT2, GRID1, HHIP, LINGO2, LMX1B, NRXN3, PARK2, QPCTL, RABEP1, RASA2, RPTOR, SBK1, SLC39A8, TAL1, USP37, ZC3H4","24"]
[null,"Cancer","metastasis","metastasis of intestinal cell lines","4,41E-03","TCF7L2","1"]
[null,"Cancer","metastasis","metastasis of cervical cancer cell lines","1,32E-02","RPTOR","1"]
[null,"Cancer","frequency","frequency of thymic lymphoma","6,61E-03","TAL1","1"]
[null,"Cancer","hyperplasia","hyperplasia of neointimal cells","6,61E-03","FOXO3","1"]
[null,"Cancer","hyperplasia","hyperplasia of neointima","1,54E-02","FOXO3","1"]
[null,"Cancer","hyperplasia","hyperplasia of pituitary gland","3,26E-02","TCF7L2","1"]
[null,"Cancer","hyperplasia","hyperplasia of T lymphocytes","4,54E-02","FOXO3","1"]
[null,"Cancer","malignant solid tumor","malignant solid tumor","6,95E-03","ASB4, C6orf106, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GNAT2, GRID1, HHIP, HIP1, HSD17B12, INO80E, KAT8, KCNK3, LINGO2, LMX1B, MAP2K5, MTCH2, NRXN3, NT5C2, PARK2, QPCTL, RABEP1, RASA2, RPTOR, SBK1, SCARB2, SLC39A8, SMG6, TAL1, TCF7L2, TOMM40, TRIM66, USP37, ZC3H4","43"]
[null,"Cancer","digestive system cancer","digestive system cancer","7,11E-03","ASB4, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GRID1, HHIP, HSD17B12, INO80E, KAT8, KCNK3, LINGO2, LMX1B, MAP2K5, NRXN3, NT5C2, PARK2, RABEP1, RASA2, RPTOR, SBK1, SCARB2, SLC39A8, SMG6, TAL1, TCF7L2, TOMM40, TRIM66, USP37, ZC3H4","38"]
[null,"Cancer","development","development of intestinal adenoma","8,80E-03","PARK2","1"]
[null,"Cancer","ovarian teratoma","ovarian teratoma","8,80E-03","FOXO3","1"]
[null,"Cancer","progression","progression of adenoma","8,80E-03","FOXO3","1"]
[null,"Cancer","apoptosis","apoptosis of medulloblastoma cells","1,10E-02","MAP2K5","1"]
[null,"Cancer","cell cycle progression","arrest in cell cycle progression of leukemia cells","1,10E-02","RPTOR","1"]
[null,"Cancer","stage IV colorectal cancer","stage IV colorectal cancer","1,10E-02","RPTOR","1"]
[null,"Cancer","transformation","transformation of myeloid progenitor cells","1,10E-02","FOXO3","1"]
[null,"Cancer","transformation","transformation of intestinal cell lines","2,40E-02","TCF7L2","1"]
[null,"Cancer","transformation","transformation of B-lymphocyte derived cell lines","3,69E-02","HIP1","1"]
[null,"Cancer","transformation","cell transformation","3,99E-02","FOXO3, HIP1, MAP2K5, TCF7L2","4"]
[null,"Cancer","tumorigenesis","tumorigenesis of prostatic adenocarcinoma","1,10E-02","HIP1","1"]
[null,"Cancer","tumorigenesis","tumorigenesis of tissue","1,16E-02","ASB4, C6orf106, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GNAT2, GRID1, HHIP, HIP1, HSD17B12, INO80E, KAT8, KCNK3, LINGO2, LMX1B, MAP2K5, MTCH2, NRXN3, NT5C2, PARK2, RABEP1, RASA2, RPTOR, SBK1, SLC39A8, SMG6, TAL1, TCF7L2, TOMM40, TRIM66, USP37, ZC3H4","41"]
[null,"Cancer","tumorigenesis","tumorigenesis of intestinal cell lines","1,54E-02","TCF7L2","1"]
[null,"Cancer","genitourinary carcinoma","genitourinary carcinoma","1,18E-02","ASB4, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ETV5, FIGN, FOXO3, GBE1, GRID1, HIP1, LINGO2, MAP2K5, MTCH2, NRXN3, NT5C2, RABEP1, RPTOR, SLC39A8, SMG6, ZC3H4","23"]
[null,"Cancer","generation","generation of tumor","1,32E-02","PARK2","1"]
[null,"Cancer","malignant cutaneous melanoma cancer","malignant cutaneous melanoma cancer","1,70E-02","ASB4, CADM2, CALCR, CLIP1, DMXL2, EHBP1, ELAVL4, FOXO3, GNAT2, GRID1, HHIP, LINGO2, LMX1B, NRXN3, QPCTL, RASA2, SBK1, SLC39A8, TAL1, USP37, ZC3H4","21"]
[null,"Cancer","invasion","invasion of prostate cancer cells","1,75E-02","MAP2K5","1"]
[null,"Cancer","invasion","invasion of cancer cells","2,71E-02","FOXO3, MAP2K5","2"]
[null,"Cancer","pancreatic carcinoid tumor","pancreatic carcinoid tumor","1,75E-02","FOXO3","1"]
[null,"Cancer","urogenital cancer","urogenital cancer","1,84E-02","ASB4, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ETV5, FIGN, FOXO3, GBE1, GRID1, HIP1, LINGO2, MAP2K5, MTCH2, NRXN3, NT5C2, PARK2, RABEP1, RPTOR, SLC39A8, SMG6, ZC3H4","24"]
[null,"Cancer","epithelial cancer","epithelial cancer","1,85E-02","ASB4, C6orf106, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GRID1, HHIP, HIP1, HSD17B12, INO80E, KAT8, KCNK3, LINGO2, LMX1B, MAP2K5, MTCH2, NRXN3, NT5C2, PARK2, RABEP1, RASA2, RPTOR, SBK1, SLC39A8, SMG6, TAL1, TCF7L2, TOMM40, TRIM66, USP37, ZC3H4","40"]
[null,"Cancer","prolactinoma","prolactinoma","2,19E-02","FOXO3","1"]
[null,"Cancer","prostate cancer","prostate cancer","2,46E-02","CALCR, DMXL2, EHBP1, ETV5, HIP1, MTCH2, NRXN3, RPTOR","8"]
[null,"Cancer","embryonal rhabdomyosarcoma","embryonal rhabdomyosarcoma","2,66E-02","ASB4, CALCR, DMXL2, GBE1, PARK2, SLC39A8","6"]
[null,"Cancer","proliferation","proliferation of multiple myeloma cells","3,05E-02","TCF7L2","1"]
[null,"Cancer","cancer","cancer of cells","3,36E-02","ASB4, C6orf106, CADM2, CLIP1, DMXL2, FOXO3, GRID1, HHIP, MTCH2, NRXN3, NT5C2, PARK2, RABEP1, RPTOR, TAL1, TCF7L2, TRIM66, ZC3H4","18"]
[null,"Cancer","squamous cell skin cancer","squamous cell skin cancer","3,82E-02","CADM2, FOXO3, HHIP, PARK2, RABEP1, RPTOR","6"]
[null,"Cancer","prostatic carcinoma","prostatic carcinoma","3,89E-02","CALCR, DMXL2, HIP1, MTCH2, NRXN3, RPTOR","6"]
[null,"Cancer","gastrointestinal tract cancer","gastrointestinal tract cancer","3,89E-02","ASB4, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GRID1, HHIP, HSD17B12, INO80E, LINGO2, MAP2K5, NRXN3, NT5C2, PARK2, RABEP1, RASA2, RPTOR, SCARB2, SLC39A8, SMG6, TCF7L2, TOMM40, TRIM66, ZC3H4","31"]
[null,"Cancer","sarcoma","sarcoma","3,99E-02","ASB4, CALCR, DMXL2, FOXO3, GBE1, HHIP, PARK2, SLC39A8","8"]
[null,"Cancer","soft tissue sarcoma cancer","soft tissue sarcoma cancer","4,08E-02","ASB4, CALCR, DMXL2, FOXO3, GBE1, PARK2, SLC39A8","7"]
[null,"Cancer","urinary tract cancer","urinary tract cancer","4,26E-02","CADM2, CLIP1, FIGN, FOXO3, GBE1, MAP2K5, NT5C2, SLC39A8, ZC3H4","9"]
[14,"Organismal Injury and Abnormalities","quantity","quantity of tumor","3,33E-04","HHIP, HIP1, PARK2, TAL1","4"]
[null,"Organismal Injury and Abnormalities","quantity","quantity of basal-cell carcinoma","2,21E-03","HHIP","1"]
[null,"Organismal Injury and Abnormalities","quantity","quantity of adenomatous polyps","6,61E-03","PARK2","1"]
[null,"Organismal Injury and Abnormalities","quantity","quantity of carcinoma cells","6,61E-03","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","quantity","quantity of malignant tumor","1,22E-02","HHIP, TAL1","2"]
[null,"Organismal Injury and Abnormalities","quantity","quantity of lymphoma","3,90E-02","TAL1","1"]
[null,"Organismal Injury and Abnormalities","hemangioma","hemangioma","4,16E-04","CADM2, FOXO3, HIP1, NRXN3, PARK2, RPTOR","6"]
[null,"Organismal Injury and Abnormalities","hemangioblastoma","hemangioblastoma","1,10E-03","CADM2, FOXO3, HIP1, PARK2, RPTOR","5"]
[null,"Organismal Injury and Abnormalities","precursor T-cell lymphoblastic leukemia-lymphoma","precursor T-cell lymphoblastic leukemia-lymphoma","1,32E-03","NT5C2, RPTOR, TAL1","3"]
[null,"Organismal Injury and Abnormalities","achromatopsia type 4","achromatopsia type 4","2,21E-03","GNAT2","1"]
[null,"Organismal Injury and Abnormalities","adult polyglucosan body disease","adult polyglucosan body disease","2,21E-03","GBE1","1"]
[null,"Organismal Injury and Abnormalities","autosomal recessive juvenile Parkinson disease type 2","autosomal recessive juvenile Parkinson disease type 2","2,21E-03","PARK2","1"]
[null,"Organismal Injury and Abnormalities","autosomal recessive spastic paraplegia type 45","autosomal recessive spastic paraplegia type 45","2,21E-03","NT5C2","1"]
[null,"Organismal Injury and Abnormalities","childhood neuromuscular glycogen storage disease type IV","childhood neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Organismal Injury and Abnormalities","classic hepatic glycogen storage disease type IV","classic hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Organismal Injury and Abnormalities","combined hepatic and myopathic glycogen storage disease type IV","combined hepatic and myopathic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Organismal Injury and Abnormalities","congenital neuromuscular glycogen storage disease type IV","congenital neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Organismal Injury and Abnormalities","dysplasia","dysplasia of podocytes","2,21E-03","LMX1B","1"]
[null,"Organismal Injury and Abnormalities","fatal perinatal neuromuscular glycogen storage disease type IV","fatal perinatal neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Organismal Injury and Abnormalities","growth retardation, developmental delay, coarse facies, and early death","growth retardation, developmental delay, coarse facies, and early death","2,21E-03","FTO","1"]
[null,"Organismal Injury and Abnormalities","hereditary prostate cancer 12","hereditary prostate cancer 12","2,21E-03","EHBP1","1"]
[null,"Organismal Injury and Abnormalities","injury","injury of inner ear","2,21E-03","GRID1","1"]
[null,"Organismal Injury and Abnormalities","nail-patella syndrome","nail-patella syndrome","2,21E-03","LMX1B","1"]
[null,"Organismal Injury and Abnormalities","nonprogressive hepatic glycogen storage disease type IV","nonprogressive hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Organismal Injury and Abnormalities","primary pulmonary hypertension 4","primary pulmonary hypertension 4","2,21E-03","KCNK3","1"]
[null,"Organismal Injury and Abnormalities","progressive myoclonic epilepsy type 4 without renal failure","progressive myoclonic epilepsy type 4 without renal failure","2,21E-03","SCARB2","1"]
[null,"Organismal Injury and Abnormalities","acute lymphocytic leukemia","acute lymphocytic leukemia","2,39E-03","FOXO3, NT5C2, RPTOR, TAL1","4"]
[null,"Organismal Injury and Abnormalities","function","abnormal function of inner ear","2,41E-03","GRID1, SCARB2","2"]
[null,"Organismal Injury and Abnormalities","function","function of vestibular hair cells","6,61E-03","SCARB2","1"]
[null,"Organismal Injury and Abnormalities","neurodegeneration","neurodegeneration of outer hair cells","2,41E-03","GRID1, SCARB2","2"]
[null,"Organismal Injury and Abnormalities","neurodegeneration","neurodegeneration of hippocampal neurons","3,69E-02","PARK2","1"]
[null,"Organismal Injury and Abnormalities","skin cancer","skin cancer","4,18E-03","ASB4, CADM2, CALCR, CLIP1, DMXL2, EHBP1, ELAVL4, FOXO3, GNAT2, GRID1, HHIP, LINGO2, LMX1B, NRXN3, PARK2, QPCTL, RABEP1, RASA2, RPTOR, SBK1, SLC39A8, TAL1, USP37, ZC3H4","24"]
[null,"Organismal Injury and Abnormalities","damage","damage of red blood cells","4,41E-03","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","damage","damage of connective tissue","1,87E-02","FOXO3, SLC39A8","2"]
[null,"Organismal Injury and Abnormalities","hypoplasia","hypoplasia of iris stroma","4,41E-03","LMX1B","1"]
[null,"Organismal Injury and Abnormalities","metastasis","metastasis of intestinal cell lines","4,41E-03","TCF7L2","1"]
[null,"Organismal Injury and Abnormalities","metastasis","metastasis of cervical cancer cell lines","1,32E-02","RPTOR","1"]
[null,"Organismal Injury and Abnormalities","progressive myoclonic epilepsy type 4 with renal failure","progressive myoclonic epilepsy type 4 with renal failure","4,41E-03","SCARB2","1"]
[null,"Organismal Injury and Abnormalities","frequency","frequency of thymic lymphoma","6,61E-03","TAL1","1"]
[null,"Organismal Injury and Abnormalities","hyperplasia","hyperplasia of neointimal cells","6,61E-03","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","hyperplasia","hyperplasia of neointima","1,54E-02","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","hyperplasia","hyperplasia of pituitary gland","3,26E-02","TCF7L2","1"]
[null,"Organismal Injury and Abnormalities","hyperplasia","hyperplasia of T lymphocytes","4,54E-02","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","malignant solid tumor","malignant solid tumor","6,95E-03","ASB4, C6orf106, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GNAT2, GRID1, HHIP, HIP1, HSD17B12, INO80E, KAT8, KCNK3, LINGO2, LMX1B, MAP2K5, MTCH2, NRXN3, NT5C2, PARK2, QPCTL, RABEP1, RASA2, RPTOR, SBK1, SCARB2, SLC39A8, SMG6, TAL1, TCF7L2, TOMM40, TRIM66, USP37, ZC3H4","43"]
[null,"Organismal Injury and Abnormalities","digestive system cancer","digestive system cancer","7,11E-03","ASB4, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GRID1, HHIP, HSD17B12, INO80E, KAT8, KCNK3, LINGO2, LMX1B, MAP2K5, NRXN3, NT5C2, PARK2, RABEP1, RASA2, RPTOR, SBK1, SCARB2, SLC39A8, SMG6, TAL1, TCF7L2, TOMM40, TRIM66, USP37, ZC3H4","38"]
[null,"Organismal Injury and Abnormalities","degeneration","degeneration of stria vascularis of cochlea","8,80E-03","SCARB2","1"]
[null,"Organismal Injury and Abnormalities","development","development of intestinal adenoma","8,80E-03","PARK2","1"]
[null,"Organismal Injury and Abnormalities","ovarian teratoma","ovarian teratoma","8,80E-03","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","progression","progression of adenoma","8,80E-03","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","apoptosis","apoptosis of medulloblastoma cells","1,10E-02","MAP2K5","1"]
[null,"Organismal Injury and Abnormalities","cell cycle progression","arrest in cell cycle progression of leukemia cells","1,10E-02","RPTOR","1"]
[null,"Organismal Injury and Abnormalities","stage IV colorectal cancer","stage IV colorectal cancer","1,10E-02","RPTOR","1"]
[null,"Organismal Injury and Abnormalities","transformation","transformation of myeloid progenitor cells","1,10E-02","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","tumorigenesis","tumorigenesis of prostatic adenocarcinoma","1,10E-02","HIP1","1"]
[null,"Organismal Injury and Abnormalities","tumorigenesis","tumorigenesis of tissue","1,16E-02","ASB4, C6orf106, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GNAT2, GRID1, HHIP, HIP1, HSD17B12, INO80E, KAT8, KCNK3, LINGO2, LMX1B, MAP2K5, MTCH2, NRXN3, NT5C2, PARK2, RABEP1, RASA2, RPTOR, SBK1, SLC39A8, SMG6, TAL1, TCF7L2, TOMM40, TRIM66, USP37, ZC3H4","41"]
[null,"Organismal Injury and Abnormalities","tumorigenesis","tumorigenesis of intestinal cell lines","1,54E-02","TCF7L2","1"]
[null,"Organismal Injury and Abnormalities","genitourinary carcinoma","genitourinary carcinoma","1,18E-02","ASB4, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ETV5, FIGN, FOXO3, GBE1, GRID1, HIP1, LINGO2, MAP2K5, MTCH2, NRXN3, NT5C2, RABEP1, RPTOR, SLC39A8, SMG6, ZC3H4","23"]
[null,"Organismal Injury and Abnormalities","generation","generation of tumor","1,32E-02","PARK2","1"]
[null,"Organismal Injury and Abnormalities","atrophy","atrophy of myotube","1,54E-02","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","atrophy","atrophy of myofiber","3,48E-02","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","malignant cutaneous melanoma cancer","malignant cutaneous melanoma cancer","1,70E-02","ASB4, CADM2, CALCR, CLIP1, DMXL2, EHBP1, ELAVL4, FOXO3, GNAT2, GRID1, HHIP, LINGO2, LMX1B, NRXN3, QPCTL, RASA2, SBK1, SLC39A8, TAL1, USP37, ZC3H4","21"]
[null,"Organismal Injury and Abnormalities","cell death","cell death of cardiomyocytes","1,72E-02","FOXO3, MAP2K5, PARK2","3"]
[null,"Organismal Injury and Abnormalities","cerebral edema","cerebral edema","1,75E-02","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","invasion","invasion of prostate cancer cells","1,75E-02","MAP2K5","1"]
[null,"Organismal Injury and Abnormalities","invasion","invasion of cancer cells","2,71E-02","FOXO3, MAP2K5","2"]
[null,"Organismal Injury and Abnormalities","pancreatic carcinoid tumor","pancreatic carcinoid tumor","1,75E-02","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","urogenital cancer","urogenital cancer","1,84E-02","ASB4, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ETV5, FIGN, FOXO3, GBE1, GRID1, HIP1, LINGO2, MAP2K5, MTCH2, NRXN3, NT5C2, PARK2, RABEP1, RPTOR, SLC39A8, SMG6, ZC3H4","24"]
[null,"Organismal Injury and Abnormalities","epithelial cancer","epithelial cancer","1,85E-02","ASB4, C6orf106, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GRID1, HHIP, HIP1, HSD17B12, INO80E, KAT8, KCNK3, LINGO2, LMX1B, MAP2K5, MTCH2, NRXN3, NT5C2, PARK2, RABEP1, RASA2, RPTOR, SBK1, SLC39A8, SMG6, TAL1, TCF7L2, TOMM40, TRIM66, USP37, ZC3H4","40"]
[null,"Organismal Injury and Abnormalities","microphthalmia","microphthalmia","1,87E-02","HIP1, LMX1B","2"]
[null,"Organismal Injury and Abnormalities","Parkinson's disease","autosomal dominant Parkinson's disease","1,97E-02","PARK2","1"]
[null,"Organismal Injury and Abnormalities","prolactinoma","prolactinoma","2,19E-02","FOXO3","1"]
[null,"Organismal Injury and Abnormalities","encephalopathy","autosomal dominant encephalopathy","2,37E-02","GNAT2, PARK2","2"]
[null,"Organismal Injury and Abnormalities","inflammatory pain","inflammatory pain","2,40E-02","LMX1B","1"]
[null,"Organismal Injury and Abnormalities","prostate cancer","prostate cancer","2,46E-02","CALCR, DMXL2, EHBP1, ETV5, HIP1, MTCH2, NRXN3, RPTOR","8"]
[null,"Organismal Injury and Abnormalities","embryonal rhabdomyosarcoma","embryonal rhabdomyosarcoma","2,66E-02","ASB4, CALCR, DMXL2, GBE1, PARK2, SLC39A8","6"]
[null,"Organismal Injury and Abnormalities","proliferation","proliferation of multiple myeloma cells","3,05E-02","TCF7L2","1"]
[null,"Organismal Injury and Abnormalities","cancer","cancer of cells","3,36E-02","ASB4, C6orf106, CADM2, CLIP1, DMXL2, FOXO3, GRID1, HHIP, MTCH2, NRXN3, NT5C2, PARK2, RABEP1, RPTOR, TAL1, TCF7L2, TRIM66, ZC3H4","18"]
[null,"Organismal Injury and Abnormalities","inborn error of carbohydrate metabolism","inborn error of carbohydrate metabolism","3,39E-02","GBE1, SLC39A8","2"]
[null,"Organismal Injury and Abnormalities","hemodynamically unstable ventricular tachycardia","hemodynamically unstable ventricular tachycardia","3,48E-02","KCNK3","1"]
[null,"Organismal Injury and Abnormalities","ventricular fibrillation","recurrent ventricular fibrillation","3,48E-02","KCNK3","1"]
[null,"Organismal Injury and Abnormalities","erosion","erosion of articular cartilage","3,69E-02","SLC39A8","1"]
[null,"Organismal Injury and Abnormalities","squamous cell skin cancer","squamous cell skin cancer","3,82E-02","CADM2, FOXO3, HHIP, PARK2, RABEP1, RPTOR","6"]
[null,"Organismal Injury and Abnormalities","prostatic carcinoma","prostatic carcinoma","3,89E-02","CALCR, DMXL2, HIP1, MTCH2, NRXN3, RPTOR","6"]
[null,"Organismal Injury and Abnormalities","gastrointestinal tract cancer","gastrointestinal tract cancer","3,89E-02","ASB4, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GRID1, HHIP, HSD17B12, INO80E, LINGO2, MAP2K5, NRXN3, NT5C2, PARK2, RABEP1, RASA2, RPTOR, SCARB2, SLC39A8, SMG6, TCF7L2, TOMM40, TRIM66, ZC3H4","31"]
[null,"Organismal Injury and Abnormalities","sarcoma","sarcoma","3,99E-02","ASB4, CALCR, DMXL2, FOXO3, GBE1, HHIP, PARK2, SLC39A8","8"]
[null,"Organismal Injury and Abnormalities","soft tissue sarcoma cancer","soft tissue sarcoma cancer","4,08E-02","ASB4, CALCR, DMXL2, FOXO3, GBE1, PARK2, SLC39A8","7"]
[null,"Organismal Injury and Abnormalities","infection","infection of spleen","4,11E-02","PARK2","1"]
[null,"Organismal Injury and Abnormalities","hypertrophy","hypertrophy of cardiomyocytes","4,23E-02","FOXO3, MAP2K5","2"]
[null,"Organismal Injury and Abnormalities","urinary tract cancer","urinary tract cancer","4,26E-02","CADM2, CLIP1, FIGN, FOXO3, GBE1, MAP2K5, NT5C2, SLC39A8, ZC3H4","9"]
[null,"Organismal Injury and Abnormalities","discomfort","discomfort","4,40E-02","CALCR, KCNK3, LMX1B","3"]
[15,"Cell-mediated Immune Response","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Cell-mediated Immune Response","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Cell-mediated Immune Response","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Cell-mediated Immune Response","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Cell-mediated Immune Response","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[16,"Cellular Development","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Cellular Development","development","development of podocytes","2,21E-03","LMX1B","1"]
[null,"Cellular Development","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Cellular Development","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Cellular Development","development","development of sperm head","4,41E-03","CLIP1","1"]
[null,"Cellular Development","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Cellular Development","development","development of mast cells","1,32E-02","TAL1","1"]
[null,"Cellular Development","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[null,"Cellular Development","development","development of retinal cone cells","3,05E-02","GNAT2","1"]
[null,"Cellular Development","development","development of follicular B lymphocytes","4,54E-02","TAL1","1"]
[null,"Cellular Development","differentiation","differentiation of nervous system","4,84E-04","ELAVL4, ETV5, FOXO3, LMX1B, RPTOR, TAL1, TCF7L2","7"]
[null,"Cellular Development","differentiation","differentiation of neurons","5,69E-03","ELAVL4, ETV5, FOXO3, LMX1B, TAL1","5"]
[null,"Cellular Development","differentiation","differentiation of B-2 lymphocytes","6,61E-03","TAL1","1"]
[null,"Cellular Development","differentiation","differentiation of dorsal root ganglion cells","6,61E-03","ETV5","1"]
[null,"Cellular Development","differentiation","differentiation of marginal-zone B lymphocytes","6,61E-03","TAL1","1"]
[null,"Cellular Development","differentiation","differentiation of podocytes","6,61E-03","LMX1B","1"]
[null,"Cellular Development","differentiation","differentiation of transitional 1 B lymphocytes","6,61E-03","TAL1","1"]
[null,"Cellular Development","differentiation","differentiation of pheochromocytoma cell lines","1,98E-02","ETV5, FOXO3","2"]
[null,"Cellular Development","differentiation","differentiation of tumor cell lines","2,10E-02","ETV5, FOXO3, GNAT2, TAL1","4"]
[null,"Cellular Development","differentiation","differentiation of bone-marrow-derived monocyte/macrophage precursor cells","2,83E-02","TAL1","1"]
[null,"Cellular Development","cell proliferation","cell proliferation of leukocyte cell lines","1,75E-03","HIP1, MAP2K5, RABEP1, TAL1","4"]
[null,"Cellular Development","cell proliferation","cell proliferation of ovarian cancer cell lines","4,18E-02","CLIP1, FOXO3","2"]
[null,"Cellular Development","maturation","maturation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Cellular Development","maturation","maturation of red blood cells","2,27E-03","FOXO3, TAL1","2"]
[null,"Cellular Development","maturation","maturation of marginal-zone B lymphocytes","6,61E-03","TAL1","1"]
[null,"Cellular Development","maturation","maturation of hematopoietic progenitor cells","1,38E-02","FOXO3, TAL1","2"]
[null,"Cellular Development","maturation","maturation of erythroid cells","3,48E-02","FOXO3","1"]
[null,"Cellular Development","maturation","maturation of leukemia cell lines","3,69E-02","FOXO3","1"]
[null,"Cellular Development","proliferation","proliferation of bone-marrow-derived monocyte/macrophage precursor cells","2,21E-03","TAL1","1"]
[null,"Cellular Development","proliferation","proliferation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Cellular Development","proliferation","proliferation of satellite cells","8,80E-03","FOXO3","1"]
[null,"Cellular Development","proliferation","proliferation of biliary epithelial cells","2,83E-02","MAP2K5","1"]
[null,"Cellular Development","proliferation","proliferation of multiple myeloma cells","3,05E-02","TCF7L2","1"]
[null,"Cellular Development","proliferation","proliferation of spermatogonia","3,48E-02","ETV5","1"]
[null,"Cellular Development","proliferation","arrest in proliferation of leukemia cell lines","4,11E-02","TAL1","1"]
[null,"Cellular Development","proliferation","proliferation of TREG cells","4,33E-02","RPTOR","1"]
[null,"Cellular Development","specification","specification of primary neurons","2,21E-03","ELAVL4","1"]
[null,"Cellular Development","epithelial-mesenchymal transition","epithelial-mesenchymal transition of tumor cell lines","2,65E-03","ETV5, FOXO3, RPTOR","3"]
[null,"Cellular Development","epithelial-mesenchymal transition","epithelial-mesenchymal transition of endometrial cancer cell lines","1,10E-02","ETV5","1"]
[null,"Cellular Development","epithelial-mesenchymal transition","epithelial-mesenchymal transition of prostate cancer cell lines","3,90E-02","FOXO3","1"]
[null,"Cellular Development","epithelial-mesenchymal transition","epithelial-mesenchymal transition of colorectal cancer cell lines","4,54E-02","RPTOR","1"]
[null,"Cellular Development","quantity","quantity of carcinoma cells","6,61E-03","FOXO3","1"]
[null,"Cellular Development","growth","arrest in growth of endothelial cells","8,80E-03","FOXO3","1"]
[null,"Cellular Development","tubulogenesis","tubulogenesis of vascular endothelial cells","1,10E-02","TAL1","1"]
[null,"Cellular Development","commitment","commitment of B lymphocytes","1,32E-02","TAL1","1"]
[null,"Cellular Development","expansion","expansion of effector T lymphocytes","1,32E-02","FOXO3","1"]
[null,"Cellular Development","expansion","expansion of motor neurons","1,32E-02","FTO","1"]
[null,"Cellular Development","generation","generation of v3 neuron","1,32E-02","FTO","1"]
[null,"Cellular Development","self-renewal","self-renewal of myeloid progenitor cells","1,32E-02","FOXO3","1"]
[null,"Cellular Development","lifespan","lifespan of red blood cells","1,75E-02","FOXO3","1"]
[null,"Cellular Development","formation","formation of sarcomere","2,19E-02","MAP2K5","1"]
[17,"Cellular Function and Maintenance","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Cellular Function and Maintenance","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Cellular Function and Maintenance","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Cellular Function and Maintenance","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Cellular Function and Maintenance","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[null,"Cellular Function and Maintenance","influx","influx of Zn2+","2,21E-03","SLC39A8","1"]
[null,"Cellular Function and Maintenance","axonal transport","arrest in axonal transport of mitochondria","4,41E-03","PARK2","1"]
[null,"Cellular Function and Maintenance","formation","formation of perinuclear vesicles","4,41E-03","HIP1","1"]
[null,"Cellular Function and Maintenance","formation","formation of sarcomere","2,19E-02","MAP2K5","1"]
[null,"Cellular Function and Maintenance","formation","formation of artificial clathrin cages","2,83E-02","HIP1","1"]
[null,"Cellular Function and Maintenance","formation","formation of aggresome","3,48E-02","PARK2","1"]
[null,"Cellular Function and Maintenance","stabilization","stabilization of cytoplasmic microtubule","4,41E-03","CLIP1","1"]
[null,"Cellular Function and Maintenance","turnover","turnover of Langerhans cells","4,41E-03","RPTOR","1"]
[null,"Cellular Function and Maintenance","autophagy","autophagy","6,45E-03","FOXO3, KAT8, LMX1B, PARK2, RPTOR","5"]
[null,"Cellular Function and Maintenance","autophagy","autophagy of cortical neurons","1,10E-02","PARK2","1"]
[null,"Cellular Function and Maintenance","autophagy","autophagy of heart","1,54E-02","PARK2","1"]
[null,"Cellular Function and Maintenance","autophagy","autophagy of muscle","1,54E-02","FOXO3","1"]
[null,"Cellular Function and Maintenance","autophagy","autophagy of neuroblastoma cell lines","1,75E-02","RPTOR","1"]
[null,"Cellular Function and Maintenance","autophagy","autophagy of mitochondria","1,97E-02","PARK2","1"]
[null,"Cellular Function and Maintenance","autophagy","autophagy of fibroblasts","3,69E-02","FOXO3","1"]
[null,"Cellular Function and Maintenance","autophagy","autophagy of cells","4,02E-02","FOXO3, PARK2, RPTOR","3"]
[null,"Cellular Function and Maintenance","function","function of vestibular hair cells","6,61E-03","SCARB2","1"]
[null,"Cellular Function and Maintenance","function","function of cytoskeleton","1,32E-02","HIP1","1"]
[null,"Cellular Function and Maintenance","homeostasis","cellular homeostasis","8,33E-03","CALCR, FOXO3, GBE1, GNAT2, KAT8, LMX1B, PARK2, RPTOR, SLC39A8, TAL1, TCF7L2","11"]
[null,"Cellular Function and Maintenance","homeostasis","homeostasis of D-glucose","1,85E-02","FOXO3, GBE1, TCF7L2","3"]
[null,"Cellular Function and Maintenance","growth","arrest in growth of endothelial cells","8,80E-03","FOXO3","1"]
[null,"Cellular Function and Maintenance","orientation","orientation of microtubules","8,80E-03","CLIP1","1"]
[null,"Cellular Function and Maintenance","production","production of follicular B lymphocytes","1,10E-02","TAL1","1"]
[null,"Cellular Function and Maintenance","reorganization","reorganization of cell-cell contacts","1,10E-02","ETV5","1"]
[null,"Cellular Function and Maintenance","tubulogenesis","tubulogenesis of vascular endothelial cells","1,10E-02","TAL1","1"]
[null,"Cellular Function and Maintenance","self-renewal","self-renewal of myeloid progenitor cells","1,32E-02","FOXO3","1"]
[null,"Cellular Function and Maintenance","glycolysis","glycolysis of lung cancer cell lines","1,54E-02","PARK2","1"]
[null,"Cellular Function and Maintenance","receptor-mediated endocytosis","receptor-mediated endocytosis of protein","1,54E-02","HIP1","1"]
[null,"Cellular Function and Maintenance","phagocytosis","phagocytosis of macrophage cancer cell lines","2,62E-02","CLIP1","1"]
[null,"Cellular Function and Maintenance","localization","localization of mitochondria","2,83E-02","PARK2","1"]
[null,"Cellular Function and Maintenance","dynamics","dynamics of microtubules","3,48E-02","CLIP1","1"]
[null,"Cellular Function and Maintenance","quantity","quantity of cilia","3,48E-02","FTO","1"]
[null,"Cellular Function and Maintenance","elevation","elevation of Ca2+ in cytosol","4,33E-02","CALCR, GNAT2","2"]
[18,"Cellular Growth and Proliferation","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Cellular Growth and Proliferation","development","development of podocytes","2,21E-03","LMX1B","1"]
[null,"Cellular Growth and Proliferation","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Cellular Growth and Proliferation","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Cellular Growth and Proliferation","development","development of sperm head","4,41E-03","CLIP1","1"]
[null,"Cellular Growth and Proliferation","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Cellular Growth and Proliferation","development","development of mast cells","1,32E-02","TAL1","1"]
[null,"Cellular Growth and Proliferation","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[null,"Cellular Growth and Proliferation","development","development of retinal cone cells","3,05E-02","GNAT2","1"]
[null,"Cellular Growth and Proliferation","development","development of follicular B lymphocytes","4,54E-02","TAL1","1"]
[null,"Cellular Growth and Proliferation","cell proliferation","cell proliferation of leukocyte cell lines","1,75E-03","HIP1, MAP2K5, RABEP1, TAL1","4"]
[null,"Cellular Growth and Proliferation","cell proliferation","cell proliferation of ovarian cancer cell lines","4,18E-02","CLIP1, FOXO3","2"]
[null,"Cellular Growth and Proliferation","proliferation","proliferation of bone-marrow-derived monocyte/macrophage precursor cells","2,21E-03","TAL1","1"]
[null,"Cellular Growth and Proliferation","proliferation","proliferation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Cellular Growth and Proliferation","proliferation","proliferation of satellite cells","8,80E-03","FOXO3","1"]
[null,"Cellular Growth and Proliferation","proliferation","proliferation of gonadal cells","1,62E-02","ETV5, FOXO3","2"]
[null,"Cellular Growth and Proliferation","proliferation","proliferation of biliary epithelial cells","2,83E-02","MAP2K5","1"]
[null,"Cellular Growth and Proliferation","proliferation","proliferation of cells","2,90E-02","CALCR, CLIP1, ELAVL4, ETV5, FOXO3, FTO, HHIP, HIP1, KAT8, KCNK3, LMX1B, MAP2K5, PARK2, RABEP1, RPTOR, TAL1, TCF7L2, USP37","18"]
[null,"Cellular Growth and Proliferation","proliferation","proliferation of multiple myeloma cells","3,05E-02","TCF7L2","1"]
[null,"Cellular Growth and Proliferation","proliferation","proliferation of spermatogonia","3,48E-02","ETV5","1"]
[null,"Cellular Growth and Proliferation","proliferation","arrest in proliferation of leukemia cell lines","4,11E-02","TAL1","1"]
[null,"Cellular Growth and Proliferation","proliferation","proliferation of TREG cells","4,33E-02","RPTOR","1"]
[null,"Cellular Growth and Proliferation","excitation","excitation of striatal neurons","4,41E-03","PARK2","1"]
[null,"Cellular Growth and Proliferation","quantity","quantity of carcinoma cells","6,61E-03","FOXO3","1"]
[null,"Cellular Growth and Proliferation","growth","arrest in growth of endothelial cells","8,80E-03","FOXO3","1"]
[null,"Cellular Growth and Proliferation","production","production of follicular B lymphocytes","1,10E-02","TAL1","1"]
[null,"Cellular Growth and Proliferation","tubulogenesis","tubulogenesis of vascular endothelial cells","1,10E-02","TAL1","1"]
[null,"Cellular Growth and Proliferation","expansion","expansion of effector T lymphocytes","1,32E-02","FOXO3","1"]
[null,"Cellular Growth and Proliferation","expansion","expansion of motor neurons","1,32E-02","FTO","1"]
[null,"Cellular Growth and Proliferation","generation","generation of v3 neuron","1,32E-02","FTO","1"]
[null,"Cellular Growth and Proliferation","formation","formation of sarcomere","2,19E-02","MAP2K5","1"]
[null,"Cellular Growth and Proliferation","suppressive capacity","suppressive capacity of TREG cells","2,40E-02","RPTOR","1"]
[null,"Cellular Growth and Proliferation","colony formation","colony formation of erythroid cells","2,62E-02","TAL1","1"]
[null,"Cellular Growth and Proliferation","colony formation","colony formation of hepatoma cell lines","2,83E-02","TCF7L2","1"]
[null,"Cellular Growth and Proliferation","colony formation","colony formation of megakaryocytes","3,69E-02","TAL1","1"]
[null,"Cellular Growth and Proliferation","colony formation","colony formation of tumor cell lines","4,19E-02","FOXO3, PARK2, TCF7L2","3"]
[null,"Cellular Growth and Proliferation","colony formation","colony formation of brain cancer cell lines","4,54E-02","PARK2","1"]
[null,"Cellular Growth and Proliferation","contact growth inhibition","contact growth inhibition of colorectal cancer cell lines","3,05E-02","FOXO3","1"]
[19,"Embryonic Development","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Embryonic Development","development","development of podocytes","2,21E-03","LMX1B","1"]
[null,"Embryonic Development","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Embryonic Development","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Embryonic Development","development","development of roof plate","4,41E-03","LMX1B","1"]
[null,"Embryonic Development","development","development of sperm head","4,41E-03","CLIP1","1"]
[null,"Embryonic Development","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Embryonic Development","development","development of midbrain-hindbrain boundary","1,32E-02","LMX1B","1"]
[null,"Embryonic Development","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[null,"Embryonic Development","development","development of myocardium","2,40E-02","MAP2K5","1"]
[null,"Embryonic Development","development","development of retina","2,42E-02","GNAT2, HHIP","2"]
[null,"Embryonic Development","development","development of head","2,79E-02","FOXO3, FTO, GNAT2, HHIP, HIP1, LMX1B, TCF7L2","7"]
[null,"Embryonic Development","development","development of retinal cone cells","3,05E-02","GNAT2","1"]
[null,"Embryonic Development","development","development of follicular B lymphocytes","4,54E-02","TAL1","1"]
[null,"Embryonic Development","cell death","cell death of embryonic tissue","4,56E-04","KAT8, TAL1, TCF7L2","3"]
[null,"Embryonic Development","necrosis","necrosis of embryonic tissue","1,17E-03","TAL1, TCF7L2","2"]
[null,"Embryonic Development","remodeling","remodeling of vitelline artery","2,21E-03","TAL1","1"]
[null,"Embryonic Development","formation","formation of pedicels","4,41E-03","LMX1B","1"]
[null,"Embryonic Development","formation","formation of podocyte slit diaphragm","4,41E-03","LMX1B","1"]
[null,"Embryonic Development","formation","formation of eye","7,78E-03","FTO, GNAT2, HHIP, HIP1, LMX1B","5"]
[null,"Embryonic Development","formation","formation of sarcomere","2,19E-02","MAP2K5","1"]
[null,"Embryonic Development","mitosis","arrest in mitosis of embryonic cell lines","6,61E-03","CLIP1","1"]
[null,"Embryonic Development","abnormal morphology","abnormal morphology of iris stroma","8,80E-03","LMX1B","1"]
[null,"Embryonic Development","abnormal morphology","abnormal morphology of ciliary body","1,75E-02","LMX1B","1"]
[null,"Embryonic Development","abnormal morphology","abnormal morphology of pupil","1,75E-02","LMX1B","1"]
[null,"Embryonic Development","abnormal morphology","abnormal morphology of anterior segment of the eye","2,54E-02","HIP1, LMX1B","2"]
[null,"Embryonic Development","abnormal morphology","abnormal morphology of anterior chamber of eye","3,05E-02","LMX1B","1"]
[null,"Embryonic Development","abnormal morphology","abnormal morphology of corneal stroma","3,90E-02","LMX1B","1"]
[null,"Embryonic Development","morphogenesis","morphogenesis of genital bud","8,80E-03","TCF7L2","1"]
[null,"Embryonic Development","morphogenesis","morphogenesis of embryonic hindgut","1,10E-02","TCF7L2","1"]
[null,"Embryonic Development","morphogenesis","morphogenesis of brain","1,13E-02","FTO, LMX1B","2"]
[null,"Embryonic Development","morphogenesis","morphogenesis of ophthalmic vesicle","1,32E-02","FTO","1"]
[null,"Embryonic Development","morphogenesis","morphogenesis of embryo","2,75E-02","FTO, LMX1B, TCF7L2","3"]
[null,"Embryonic Development","morphogenesis","morphogenesis of head","3,07E-02","FTO, LMX1B, TCF7L2","3"]
[null,"Embryonic Development","morphogenesis","morphogenesis of cerebellum","3,48E-02","LMX1B","1"]
[null,"Embryonic Development","tubulogenesis","tubulogenesis of vascular endothelial cells","1,10E-02","TAL1","1"]
[null,"Embryonic Development","degeneration","degeneration of floor plate","1,32E-02","FTO","1"]
[null,"Embryonic Development","G2 phase","arrest in G2 phase of embryonic cell lines","2,62E-02","CALCR","1"]
[null,"Embryonic Development","apoptosis","apoptosis of embryoblast","4,33E-02","KAT8","1"]
[20,"Organ Development","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Organ Development","development","development of podocytes","2,21E-03","LMX1B","1"]
[null,"Organ Development","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Organ Development","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Organ Development","development","development of sperm head","4,41E-03","CLIP1","1"]
[null,"Organ Development","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Organ Development","development","development of midbrain-hindbrain boundary","1,32E-02","LMX1B","1"]
[null,"Organ Development","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[null,"Organ Development","development","development of myocardium","2,40E-02","MAP2K5","1"]
[null,"Organ Development","development","development of retina","2,42E-02","GNAT2, HHIP","2"]
[null,"Organ Development","development","development of retinal cone cells","3,05E-02","GNAT2","1"]
[null,"Organ Development","development","development of follicular B lymphocytes","4,54E-02","TAL1","1"]
[null,"Organ Development","growth","initiation of growth of primordial ovarian follicle","2,21E-03","FOXO3","1"]
[null,"Organ Development","growth","growth of atretic ovarian follicle","6,61E-03","FOXO3","1"]
[null,"Organ Development","outgrowth","outgrowth of glomerular capillary","2,21E-03","LMX1B","1"]
[null,"Organ Development","proliferation","proliferation of heart","2,21E-03","MAP2K5","1"]
[null,"Organ Development","proliferation","proliferation of gonadal cells","1,62E-02","ETV5, FOXO3","2"]
[null,"Organ Development","proliferation","proliferation of spermatogonia","3,48E-02","ETV5","1"]
[null,"Organ Development","function","abnormal function of inner ear","2,41E-03","GRID1, SCARB2","2"]
[null,"Organ Development","function","function of vestibular hair cells","6,61E-03","SCARB2","1"]
[null,"Organ Development","function","function of adrenal gland","2,19E-02","KCNK3","1"]
[null,"Organ Development","formation","formation of pedicels","4,41E-03","LMX1B","1"]
[null,"Organ Development","formation","formation of podocyte slit diaphragm","4,41E-03","LMX1B","1"]
[null,"Organ Development","formation","formation of eye","7,78E-03","FTO, GNAT2, HHIP, HIP1, LMX1B","5"]
[null,"Organ Development","formation","formation of sarcomere","2,19E-02","MAP2K5","1"]
[null,"Organ Development","abnormal morphology","abnormal morphology of iris stroma","8,80E-03","LMX1B","1"]
[null,"Organ Development","abnormal morphology","abnormal morphology of ciliary body","1,75E-02","LMX1B","1"]
[null,"Organ Development","abnormal morphology","abnormal morphology of pupil","1,75E-02","LMX1B","1"]
[null,"Organ Development","abnormal morphology","abnormal morphology of anterior segment of the eye","2,54E-02","HIP1, LMX1B","2"]
[null,"Organ Development","abnormal morphology","abnormal morphology of anterior chamber of eye","3,05E-02","LMX1B","1"]
[null,"Organ Development","abnormal morphology","abnormal morphology of corneal stroma","3,90E-02","LMX1B","1"]
[null,"Organ Development","morphogenesis","morphogenesis of brain","1,13E-02","FTO, LMX1B","2"]
[null,"Organ Development","morphogenesis","morphogenesis of cerebellum","3,48E-02","LMX1B","1"]
[null,"Organ Development","elongation","elongation of cardiomyocytes","1,54E-02","MAP2K5","1"]
[21,"Organismal Development","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Organismal Development","development","development of podocytes","2,21E-03","LMX1B","1"]
[null,"Organismal Development","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Organismal Development","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Organismal Development","development","development of roof plate","4,41E-03","LMX1B","1"]
[null,"Organismal Development","development","development of sperm head","4,41E-03","CLIP1","1"]
[null,"Organismal Development","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Organismal Development","development","development of midbrain-hindbrain boundary","1,32E-02","LMX1B","1"]
[null,"Organismal Development","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[null,"Organismal Development","development","development of myocardium","2,40E-02","MAP2K5","1"]
[null,"Organismal Development","development","development of retina","2,42E-02","GNAT2, HHIP","2"]
[null,"Organismal Development","development","development of head","2,79E-02","FOXO3, FTO, GNAT2, HHIP, HIP1, LMX1B, TCF7L2","7"]
[null,"Organismal Development","development","development of retinal cone cells","3,05E-02","GNAT2","1"]
[null,"Organismal Development","development","development of follicular B lymphocytes","4,54E-02","TAL1","1"]
[null,"Organismal Development","size","size of mesencephalon","4,26E-04","FTO, LMX1B","2"]
[null,"Organismal Development","size","size of superior colliculus","4,41E-03","LMX1B","1"]
[null,"Organismal Development","size","size of brain","8,74E-03","FOXO3, FTO, LMX1B","3"]
[null,"Organismal Development","size","size of olfactory bulb","1,10E-02","FOXO3","1"]
[null,"Organismal Development","size","size of pallium","1,32E-02","FTO","1"]
[null,"Organismal Development","size","size of dentate gyrus","1,54E-02","FOXO3","1"]
[null,"Organismal Development","size","size of body","4,09E-02","ETV5, FTO, GRID1, KAT8, PARK2, SCARB2","6"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of enlarged adenohypophysis","2,21E-03","TCF7L2","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of mesencephalon","4,25E-03","LMX1B, PARK2","2"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of small scapula","6,61E-03","LMX1B","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of iris stroma","8,80E-03","LMX1B","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of locus ceruleus","8,80E-03","PARK2","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of pretectum","8,80E-03","LMX1B","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of otolithic membrane","1,10E-02","SCARB2","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of enlarged ovary","1,32E-02","FOXO3","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of intermediate lobe of the pituitary gland","1,32E-02","TCF7L2","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of enlarged pituitary gland","1,54E-02","TCF7L2","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of marginal stria vascularis cells","1,54E-02","SCARB2","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of pedicels","1,54E-02","LMX1B","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of head","1,60E-02","FIGN, FTO, HIP1, LMX1B, PARK2, SCARB2, TCF7L2","7"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of ciliary body","1,75E-02","LMX1B","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of pupil","1,75E-02","LMX1B","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of superior colliculus","1,75E-02","LMX1B","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of substantia nigra","1,97E-02","PARK2","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of anterior segment of the eye","2,54E-02","HIP1, LMX1B","2"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of clavicle","2,62E-02","LMX1B","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of enterocytes","2,62E-02","TCF7L2","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of fontanelle","2,62E-02","LMX1B","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of anterior chamber of eye","3,05E-02","LMX1B","1"]
[null,"Organismal Development","abnormal morphology","abnormal morphology of corneal stroma","3,90E-02","LMX1B","1"]
[null,"Organismal Development","growth retardation, developmental delay, coarse facies, and early death","growth retardation, developmental delay, coarse facies, and early death","2,21E-03","FTO","1"]
[null,"Organismal Development","outgrowth","outgrowth of glomerular capillary","2,21E-03","LMX1B","1"]
[null,"Organismal Development","formation","formation of pedicels","4,41E-03","LMX1B","1"]
[null,"Organismal Development","formation","formation of podocyte slit diaphragm","4,41E-03","LMX1B","1"]
[null,"Organismal Development","formation","formation of eye","7,78E-03","FTO, GNAT2, HHIP, HIP1, LMX1B","5"]
[null,"Organismal Development","formation","formation of sarcomere","2,19E-02","MAP2K5","1"]
[null,"Organismal Development","lack","lack of ilium","4,41E-03","LMX1B","1"]
[null,"Organismal Development","lack","lack of podocyte slit diaphragm","1,10E-02","LMX1B","1"]
[null,"Organismal Development","lack","lack of supraoccipital bone","1,10E-02","LMX1B","1"]
[null,"Organismal Development","lack","lack of pedicels","1,32E-02","LMX1B","1"]
[null,"Organismal Development","lack","lack of ulna","1,32E-02","LMX1B","1"]
[null,"Organismal Development","lack","lack of otoliths","1,54E-02","SCARB2","1"]
[null,"Organismal Development","lack","lack of patella","1,54E-02","LMX1B","1"]
[null,"Organismal Development","morphology","morphology of head","5,97E-03","FIGN, FTO, GRID1, HIP1, LMX1B, PARK2, SCARB2, TCF7L2","8"]
[null,"Organismal Development","morphology","morphology of brain","1,01E-02","FTO, GRID1, LMX1B, PARK2, TCF7L2","5"]
[null,"Organismal Development","morphology","morphology of cerebral cortex","1,47E-02","GRID1, LMX1B, PARK2","3"]
[null,"Organismal Development","morphology","morphology of endothelial tissue","1,48E-02","LMX1B, MAP2K5","2"]
[null,"Organismal Development","growth","arrest in growth of endothelial cells","8,80E-03","FOXO3","1"]
[null,"Organismal Development","morphogenesis","morphogenesis of genital bud","8,80E-03","TCF7L2","1"]
[null,"Organismal Development","morphogenesis","morphogenesis of embryonic hindgut","1,10E-02","TCF7L2","1"]
[null,"Organismal Development","morphogenesis","morphogenesis of brain","1,13E-02","FTO, LMX1B","2"]
[null,"Organismal Development","morphogenesis","morphogenesis of ophthalmic vesicle","1,32E-02","FTO","1"]
[null,"Organismal Development","morphogenesis","morphogenesis of embryo","2,75E-02","FTO, LMX1B, TCF7L2","3"]
[null,"Organismal Development","morphogenesis","morphogenesis of head","3,07E-02","FTO, LMX1B, TCF7L2","3"]
[null,"Organismal Development","morphogenesis","morphogenesis of cerebellum","3,48E-02","LMX1B","1"]
[null,"Organismal Development","congenital malformation","congenital malformation of face","1,06E-02","FIGN, FTO, TCF7L2","3"]
[null,"Organismal Development","tubulogenesis","tubulogenesis of vascular endothelial cells","1,10E-02","TAL1","1"]
[null,"Organismal Development","maturation","maturation of blood vessel","3,90E-02","FOXO3","1"]
[22,"Tissue Development","development","development of double-negative T lymphocyte","3,66E-04","RPTOR, TAL1","2"]
[null,"Tissue Development","development","development of podocytes","2,21E-03","LMX1B","1"]
[null,"Tissue Development","development","development of DN1 cells","4,41E-03","RPTOR","1"]
[null,"Tissue Development","development","development of DN2 cells","4,41E-03","RPTOR","1"]
[null,"Tissue Development","development","development of roof plate","4,41E-03","LMX1B","1"]
[null,"Tissue Development","development","development of sperm head","4,41E-03","CLIP1","1"]
[null,"Tissue Development","development","development of pro-T3 thymocytes","8,80E-03","RPTOR","1"]
[null,"Tissue Development","development","development of mast cells","1,32E-02","TAL1","1"]
[null,"Tissue Development","development","development of midbrain-hindbrain boundary","1,32E-02","LMX1B","1"]
[null,"Tissue Development","development","development of double-positive thymocyte","1,97E-02","TAL1","1"]
[null,"Tissue Development","development","development of myocardium","2,40E-02","MAP2K5","1"]
[null,"Tissue Development","development","development of retina","2,42E-02","GNAT2, HHIP","2"]
[null,"Tissue Development","development","development of retinal cone cells","3,05E-02","GNAT2","1"]
[null,"Tissue Development","development","development of follicular B lymphocytes","4,54E-02","TAL1","1"]
[null,"Tissue Development","accumulation","accumulation of memory precursor T lymphocytes","2,21E-03","FOXO3","1"]
[null,"Tissue Development","accumulation","accumulation of T lymphocytes","2,63E-02","FOXO3, TAL1","2"]
[null,"Tissue Development","maturation","maturation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Tissue Development","maturation","maturation of red blood cells","2,27E-03","FOXO3, TAL1","2"]
[null,"Tissue Development","maturation","maturation of erythroid cells","3,48E-02","FOXO3","1"]
[null,"Tissue Development","proliferation","proliferation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Tissue Development","proliferation","proliferation of biliary epithelial cells","2,83E-02","MAP2K5","1"]
[null,"Tissue Development","specification","specification of primary neurons","2,21E-03","ELAVL4","1"]
[null,"Tissue Development","formation","formation of pedicels","4,41E-03","LMX1B","1"]
[null,"Tissue Development","formation","formation of podocyte slit diaphragm","4,41E-03","LMX1B","1"]
[null,"Tissue Development","formation","formation of eye","7,78E-03","FTO, GNAT2, HHIP, HIP1, LMX1B","5"]
[null,"Tissue Development","formation","formation of sarcomere","2,19E-02","MAP2K5","1"]
[null,"Tissue Development","lack","lack of ilium","4,41E-03","LMX1B","1"]
[null,"Tissue Development","lack","lack of supraoccipital bone","1,10E-02","LMX1B","1"]
[null,"Tissue Development","lack","lack of ulna","1,32E-02","LMX1B","1"]
[null,"Tissue Development","lack","lack of patella","1,54E-02","LMX1B","1"]
[null,"Tissue Development","differentiation","differentiation of neurons","5,69E-03","ELAVL4, ETV5, FOXO3, LMX1B, TAL1","5"]
[null,"Tissue Development","differentiation","differentiation of dorsal root ganglion cells","6,61E-03","ETV5","1"]
[null,"Tissue Development","abnormal morphology","abnormal morphology of small scapula","6,61E-03","LMX1B","1"]
[null,"Tissue Development","abnormal morphology","abnormal morphology of iris stroma","8,80E-03","LMX1B","1"]
[null,"Tissue Development","abnormal morphology","abnormal morphology of ciliary body","1,75E-02","LMX1B","1"]
[null,"Tissue Development","abnormal morphology","abnormal morphology of pupil","1,75E-02","LMX1B","1"]
[null,"Tissue Development","abnormal morphology","abnormal morphology of anterior segment of the eye","2,54E-02","HIP1, LMX1B","2"]
[null,"Tissue Development","abnormal morphology","abnormal morphology of clavicle","2,62E-02","LMX1B","1"]
[null,"Tissue Development","abnormal morphology","abnormal morphology of fontanelle","2,62E-02","LMX1B","1"]
[null,"Tissue Development","abnormal morphology","abnormal morphology of anterior chamber of eye","3,05E-02","LMX1B","1"]
[null,"Tissue Development","abnormal morphology","abnormal morphology of corneal stroma","3,90E-02","LMX1B","1"]
[null,"Tissue Development","function","function of vestibular hair cells","6,61E-03","SCARB2","1"]
[null,"Tissue Development","growth","arrest in growth of endothelial cells","8,80E-03","FOXO3","1"]
[null,"Tissue Development","morphogenesis","morphogenesis of genital bud","8,80E-03","TCF7L2","1"]
[null,"Tissue Development","morphogenesis","morphogenesis of embryonic hindgut","1,10E-02","TCF7L2","1"]
[null,"Tissue Development","morphogenesis","morphogenesis of brain","1,13E-02","FTO, LMX1B","2"]
[null,"Tissue Development","morphogenesis","morphogenesis of ophthalmic vesicle","1,32E-02","FTO","1"]
[null,"Tissue Development","morphogenesis","morphogenesis of cerebellum","3,48E-02","LMX1B","1"]
[null,"Tissue Development","tubulogenesis","tubulogenesis of vascular endothelial cells","1,10E-02","TAL1","1"]
[null,"Tissue Development","expansion","expansion of motor neurons","1,32E-02","FTO","1"]
[null,"Tissue Development","generation","generation of v3 neuron","1,32E-02","FTO","1"]
[null,"Tissue Development","self-renewal","self-renewal of myeloid progenitor cells","1,32E-02","FOXO3","1"]
[null,"Tissue Development","production","production of extracellular matrix","1,75E-02","MAP2K5","1"]
[23,"Cardiovascular Disease","hemangioma","hemangioma","4,16E-04","CADM2, FOXO3, HIP1, NRXN3, PARK2, RPTOR","6"]
[null,"Cardiovascular Disease","hemangioblastoma","hemangioblastoma","1,10E-03","CADM2, FOXO3, HIP1, PARK2, RPTOR","5"]
[null,"Cardiovascular Disease","primary pulmonary hypertension 4","primary pulmonary hypertension 4","2,21E-03","KCNK3","1"]
[null,"Cardiovascular Disease","hypercholesterolemia","Hypercholesterolemia","9,08E-03","FOXO3, RPTOR","2"]
[null,"Cardiovascular Disease","hyperplasia","hyperplasia of neointima","1,54E-02","FOXO3","1"]
[null,"Cardiovascular Disease","cell death","cell death of cardiomyocytes","1,72E-02","FOXO3, MAP2K5, PARK2","3"]
[null,"Cardiovascular Disease","hemodynamically unstable ventricular tachycardia","hemodynamically unstable ventricular tachycardia","3,48E-02","KCNK3","1"]
[null,"Cardiovascular Disease","ventricular fibrillation","recurrent ventricular fibrillation","3,48E-02","KCNK3","1"]
[null,"Cardiovascular Disease","hypertrophy","hypertrophy of cardiomyocytes","4,23E-02","FOXO3, MAP2K5","2"]
[24,"Organ Morphology","size","size of mesencephalon","4,26E-04","FTO, LMX1B","2"]
[null,"Organ Morphology","size","size of superior colliculus","4,41E-03","LMX1B","1"]
[null,"Organ Morphology","size","size of brain","8,74E-03","FOXO3, FTO, LMX1B","3"]
[null,"Organ Morphology","size","size of olfactory bulb","1,10E-02","FOXO3","1"]
[null,"Organ Morphology","size","size of pallium","1,32E-02","FTO","1"]
[null,"Organ Morphology","size","size of dentate gyrus","1,54E-02","FOXO3","1"]
[null,"Organ Morphology","size","size of muscle cells","3,78E-02","FOXO3, SCARB2","2"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of enlarged adenohypophysis","2,21E-03","TCF7L2","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of mesencephalon","4,25E-03","LMX1B, PARK2","2"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of small scapula","6,61E-03","LMX1B","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of iris stroma","8,80E-03","LMX1B","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of locus ceruleus","8,80E-03","PARK2","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of pretectum","8,80E-03","LMX1B","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of germ cells","9,24E-03","ETV5, FOXO3, HIP1","3"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of otolithic membrane","1,10E-02","SCARB2","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of vomeronasal organ","1,10E-02","ETV5","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of enlarged ovary","1,32E-02","FOXO3","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of intermediate lobe of the pituitary gland","1,32E-02","TCF7L2","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of enlarged pituitary gland","1,54E-02","TCF7L2","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of marginal stria vascularis cells","1,54E-02","SCARB2","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of pedicels","1,54E-02","LMX1B","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of ciliary body","1,75E-02","LMX1B","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of pupil","1,75E-02","LMX1B","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of superior colliculus","1,75E-02","LMX1B","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of substantia nigra","1,97E-02","PARK2","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of anterior segment of the eye","2,54E-02","HIP1, LMX1B","2"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of clavicle","2,62E-02","LMX1B","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of enterocytes","2,62E-02","TCF7L2","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of male germ cells","2,89E-02","ETV5, HIP1","2"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of anterior chamber of eye","3,05E-02","LMX1B","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of corneal stroma","3,90E-02","LMX1B","1"]
[null,"Organ Morphology","abnormal morphology","abnormal morphology of spermatogonia","4,54E-02","ETV5","1"]
[null,"Organ Morphology","quantity","quantity of pedicels","2,21E-03","LMX1B","1"]
[null,"Organ Morphology","quantity","quantity of podocyte slit diaphragm","4,41E-03","LMX1B","1"]
[null,"Organ Morphology","quantity","quantity of enterocytes","6,61E-03","TCF7L2","1"]
[null,"Organ Morphology","lack","lack of ilium","4,41E-03","LMX1B","1"]
[null,"Organ Morphology","lack","lack of podocyte slit diaphragm","1,10E-02","LMX1B","1"]
[null,"Organ Morphology","lack","lack of pedicels","1,32E-02","LMX1B","1"]
[null,"Organ Morphology","lack","lack of ulna","1,32E-02","LMX1B","1"]
[null,"Organ Morphology","lack","lack of otoliths","1,54E-02","SCARB2","1"]
[null,"Organ Morphology","lack","lack of patella","1,54E-02","LMX1B","1"]
[null,"Organ Morphology","area","area of beta islet cells","8,80E-03","TCF7L2","1"]
[null,"Organ Morphology","morphology","morphology of brain","1,01E-02","FTO, GRID1, LMX1B, PARK2, TCF7L2","5"]
[null,"Organ Morphology","morphology","morphology of cerebral cortex","1,47E-02","GRID1, LMX1B, PARK2","3"]
[null,"Organ Morphology","morphogenesis","morphogenesis of brain","1,13E-02","FTO, LMX1B","2"]
[null,"Organ Morphology","morphogenesis","morphogenesis of cerebellum","3,48E-02","LMX1B","1"]
[null,"Organ Morphology","erosion","erosion of articular cartilage","3,69E-02","SLC39A8","1"]
[25,"Developmental Disorder","necrosis","necrosis of embryonic tissue","1,17E-03","TAL1, TCF7L2","2"]
[null,"Developmental Disorder","Paget's disease of bone","symptomatic stage Paget's disease of bone","2,21E-03","CALCR","1"]
[null,"Developmental Disorder","adult polyglucosan body disease","adult polyglucosan body disease","2,21E-03","GBE1","1"]
[null,"Developmental Disorder","bilateral hyperpronation","bilateral hyperpronation","2,21E-03","TCF7L2","1"]
[null,"Developmental Disorder","childhood neuromuscular glycogen storage disease type IV","childhood neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Developmental Disorder","classic hepatic glycogen storage disease type IV","classic hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Developmental Disorder","combined hepatic and myopathic glycogen storage disease type IV","combined hepatic and myopathic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Developmental Disorder","congenital neuromuscular glycogen storage disease type IV","congenital neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Developmental Disorder","dysplasia","dysplasia of podocytes","2,21E-03","LMX1B","1"]
[null,"Developmental Disorder","fatal perinatal neuromuscular glycogen storage disease type IV","fatal perinatal neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Developmental Disorder","growth retardation, developmental delay, coarse facies, and early death","growth retardation, developmental delay, coarse facies, and early death","2,21E-03","FTO","1"]
[null,"Developmental Disorder","kyphosis","kyphosis of thoracolumbar spine","2,21E-03","HIP1","1"]
[null,"Developmental Disorder","kyphosis","kyphosis","2,06E-02","HIP1, PARK2","2"]
[null,"Developmental Disorder","nail-patella syndrome","nail-patella syndrome","2,21E-03","LMX1B","1"]
[null,"Developmental Disorder","nonprogressive hepatic glycogen storage disease type IV","nonprogressive hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Developmental Disorder","hypoplasia","hypoplasia of iris stroma","4,41E-03","LMX1B","1"]
[null,"Developmental Disorder","mental retardation","severe mental retardation","6,61E-03","TCF7L2","1"]
[null,"Developmental Disorder","congenital anomaly of limb","congenital anomaly of limb","8,99E-03","ETV5, LMX1B, TCF7L2","3"]
[null,"Developmental Disorder","congenital malformation","congenital malformation of face","1,06E-02","FIGN, FTO, TCF7L2","3"]
[null,"Developmental Disorder","degeneration","degeneration of floor plate","1,32E-02","FTO","1"]
[null,"Developmental Disorder","microphthalmia","microphthalmia","1,87E-02","HIP1, LMX1B","2"]
[null,"Developmental Disorder","hypertrophy","hypertrophy of myofiber","2,19E-02","FOXO3","1"]
[null,"Developmental Disorder","hypertrophy","hypertrophy of cardiomyocytes","4,23E-02","FOXO3, MAP2K5","2"]
[null,"Developmental Disorder","inborn error of carbohydrate metabolism","inborn error of carbohydrate metabolism","3,39E-02","GBE1, SLC39A8","2"]
[26,"Hematological Disease","precursor T-cell lymphoblastic leukemia-lymphoma","precursor T-cell lymphoblastic leukemia-lymphoma","1,32E-03","NT5C2, RPTOR, TAL1","3"]
[null,"Hematological Disease","acute lymphocytic leukemia","acute lymphocytic leukemia","2,39E-03","FOXO3, NT5C2, RPTOR, TAL1","4"]
[null,"Hematological Disease","fasting hypoglycemia","fasting hypoglycemia","6,61E-03","FOXO3","1"]
[null,"Hematological Disease","frequency","frequency of thymic lymphoma","6,61E-03","TAL1","1"]
[null,"Hematological Disease","hypercapnia","hypercapnia","8,80E-03","KCNK3","1"]
[null,"Hematological Disease","hypercholesterolemia","Hypercholesterolemia","9,08E-03","FOXO3, RPTOR","2"]
[null,"Hematological Disease","hypokalemia","hypokalemia","2,83E-02","KCNK3","1"]
[null,"Hematological Disease","proliferation","proliferation of multiple myeloma cells","3,05E-02","TCF7L2","1"]
[null,"Hematological Disease","hypoglycemia","hypoglycemia","3,07E-02","FOXO3, TCF7L2","2"]
[null,"Hematological Disease","quantity","quantity of lymphoma","3,90E-02","TAL1","1"]
[null,"Hematological Disease","hyperplasia","hyperplasia of T lymphocytes","4,54E-02","FOXO3","1"]
[27,"Immunological Disease","precursor T-cell lymphoblastic leukemia-lymphoma","precursor T-cell lymphoblastic leukemia-lymphoma","1,32E-03","NT5C2, RPTOR, TAL1","3"]
[null,"Immunological Disease","acute lymphocytic leukemia","acute lymphocytic leukemia","2,39E-03","FOXO3, NT5C2, RPTOR, TAL1","4"]
[null,"Immunological Disease","frequency","frequency of thymic lymphoma","6,61E-03","TAL1","1"]
[null,"Immunological Disease","proliferation","proliferation of multiple myeloma cells","3,05E-02","TCF7L2","1"]
[null,"Immunological Disease","quantity","quantity of lymphoma","3,90E-02","TAL1","1"]
[null,"Immunological Disease","infection","infection of spleen","4,11E-02","PARK2","1"]
[null,"Immunological Disease","hyperplasia","hyperplasia of T lymphocytes","4,54E-02","FOXO3","1"]
[28,"Nucleic Acid Metabolism","biosynthesis","biosynthesis of nucleoside triphosphate","1,94E-03","FOXO3, NT5C2, PARK2","3"]
[null,"Nucleic Acid Metabolism","quantity","quantity of guanosine","2,21E-03","NT5C2","1"]
[null,"Nucleic Acid Metabolism","quantity","quantity of inosine","6,61E-03","NT5C2","1"]
[null,"Nucleic Acid Metabolism","quantity","quantity of NAD+","3,90E-02","FOXO3","1"]
[null,"Nucleic Acid Metabolism","inactivation","inactivation of cytarabine","4,41E-03","NT5C2","1"]
[null,"Nucleic Acid Metabolism","synthesis","synthesis of GMP","8,80E-03","NT5C2","1"]
[null,"Nucleic Acid Metabolism","synthesis","synthesis of GTP","8,80E-03","NT5C2","1"]
[null,"Nucleic Acid Metabolism","synthesis","synthesis of purine nucleotide","9,37E-03","FOXO3, NT5C2, PARK2","3"]
[null,"Nucleic Acid Metabolism","synthesis","synthesis of GDP","1,54E-02","NT5C2","1"]
[null,"Nucleic Acid Metabolism","synthesis","synthesis of nucleotide","1,73E-02","CALCR, FOXO3, NT5C2, PARK2","4"]
[null,"Nucleic Acid Metabolism","synthesis","synthesis of ATP","1,87E-02","FOXO3, PARK2","2"]
[null,"Nucleic Acid Metabolism","metabolism","metabolism of adenosine","2,83E-02","NT5C2","1"]
[29,"Small Molecule Biochemistry","biosynthesis","biosynthesis of nucleoside triphosphate","1,94E-03","FOXO3, NT5C2, PARK2","3"]
[null,"Small Molecule Biochemistry","activation","activation of paclitaxel","2,21E-03","CLIP1","1"]
[null,"Small Molecule Biochemistry","peroxidation","peroxidation of protein","2,21E-03","PARK2","1"]
[null,"Small Molecule Biochemistry","quantity","quantity of guanosine","2,21E-03","NT5C2","1"]
[null,"Small Molecule Biochemistry","quantity","quantity of hypoxanthine","4,41E-03","NT5C2","1"]
[null,"Small Molecule Biochemistry","quantity","quantity of inosine","6,61E-03","NT5C2","1"]
[null,"Small Molecule Biochemistry","quantity","quantity of nitrite","3,26E-02","PARK2","1"]
[null,"Small Molecule Biochemistry","quantity","quantity of renin in blood","3,69E-02","KCNK3","1"]
[null,"Small Molecule Biochemistry","quantity","quantity of steroid","4,31E-02","FOXO3, KCNK3, RPTOR, TCF7L2","4"]
[null,"Small Molecule Biochemistry","inactivation","inactivation of cytarabine","4,41E-03","NT5C2","1"]
[null,"Small Molecule Biochemistry","binding","binding of phosphatidylinositol 3,5-diphosphate","6,61E-03","HIP1","1"]
[null,"Small Molecule Biochemistry","binding","binding of phosphatidylinositol 3,4-diphosphate","8,80E-03","HIP1","1"]
[null,"Small Molecule Biochemistry","binding","binding of phosphatidylinositol-3-phosphate","8,80E-03","HIP1","1"]
[null,"Small Molecule Biochemistry","synthesis","synthesis of GMP","8,80E-03","NT5C2","1"]
[null,"Small Molecule Biochemistry","synthesis","synthesis of GTP","8,80E-03","NT5C2","1"]
[null,"Small Molecule Biochemistry","synthesis","synthesis of purine nucleotide","9,37E-03","FOXO3, NT5C2, PARK2","3"]
[null,"Small Molecule Biochemistry","synthesis","synthesis of GDP","1,54E-02","NT5C2","1"]
[null,"Small Molecule Biochemistry","synthesis","synthesis of nucleotide","1,73E-02","CALCR, FOXO3, NT5C2, PARK2","4"]
[null,"Small Molecule Biochemistry","synthesis","synthesis of ATP","1,87E-02","FOXO3, PARK2","2"]
[null,"Small Molecule Biochemistry","synthesis","synthesis of heparan sulfate proteoglycan","3,05E-02","TCF7L2","1"]
[null,"Small Molecule Biochemistry","catabolism","catabolism of dopamine","1,32E-02","PARK2","1"]
[null,"Small Molecule Biochemistry","homeostasis","homeostasis of D-glucose","1,85E-02","FOXO3, GBE1, TCF7L2","3"]
[null,"Small Molecule Biochemistry","release","release of lactic acid","1,97E-02","NT5C2","1"]
[null,"Small Molecule Biochemistry","metabolism","metabolism of norepinephrine","2,40E-02","PARK2","1"]
[null,"Small Molecule Biochemistry","metabolism","metabolism of adenosine","2,83E-02","NT5C2","1"]
[null,"Small Molecule Biochemistry","abnormal quantity","abnormal quantity of dopamine","3,26E-02","PARK2","1"]
[null,"Small Molecule Biochemistry","incorporation","incorporation of D-glucose","3,26E-02","NT5C2","1"]
[null,"Small Molecule Biochemistry","concentration","concentration of cholesterol","4,43E-02","FOXO3, RPTOR, TCF7L2","3"]
[30,"Cellular Movement","scattering","scattering of tumor cell lines","1,99E-03","ETV5, MTCH2","2"]
[null,"Cellular Movement","scattering","scattering of endometrial cancer cell lines","2,21E-03","ETV5","1"]
[null,"Cellular Movement","scattering","scattering of adenocarcinoma cell lines","4,41E-03","MTCH2","1"]
[null,"Cellular Movement","migratory capacity","migratory capacity of endometrial cancer cell lines","2,21E-03","ETV5","1"]
[null,"Cellular Movement","release","release of blood platelets","1,32E-02","TAL1","1"]
[null,"Cellular Movement","rearrangement","rearrangement of cells","1,54E-02","ETV5","1"]
[null,"Cellular Movement","invasion","invasion of prostate cancer cells","1,75E-02","MAP2K5","1"]
[null,"Cellular Movement","invasion","invasion of endometrial cancer cell lines","2,40E-02","ETV5","1"]
[null,"Cellular Movement","invasion","invasion of cancer cells","2,71E-02","FOXO3, MAP2K5","2"]
[null,"Cellular Movement","cell movement","cell movement of prostate cancer cells","3,48E-02","MAP2K5","1"]
[null,"Cellular Movement","migration","migration of Langerhans cells","4,33E-02","RPTOR","1"]
[31,"Auditory Disease","injury","injury of inner ear","2,21E-03","GRID1","1"]
[null,"Auditory Disease","function","abnormal function of inner ear","2,41E-03","GRID1, SCARB2","2"]
[null,"Auditory Disease","function","function of vestibular hair cells","6,61E-03","SCARB2","1"]
[null,"Auditory Disease","neurodegeneration","neurodegeneration of outer hair cells","2,41E-03","GRID1, SCARB2","2"]
[null,"Auditory Disease","degeneration","degeneration of stria vascularis of cochlea","8,80E-03","SCARB2","1"]
[null,"Auditory Disease","noise-induced hearing loss","noise-induced hearing loss","2,19E-02","GRID1","1"]
[32,"Cardiovascular System Development and Function","outgrowth","outgrowth of glomerular capillary","2,21E-03","LMX1B","1"]
[null,"Cardiovascular System Development and Function","remodeling","remodeling of vitelline artery","2,21E-03","TAL1","1"]
[null,"Cardiovascular System Development and Function","growth","arrest in growth of endothelial cells","8,80E-03","FOXO3","1"]
[null,"Cardiovascular System Development and Function","tubulogenesis","tubulogenesis of vascular endothelial cells","1,10E-02","TAL1","1"]
[null,"Cardiovascular System Development and Function","morphology","morphology of endothelial tissue","1,48E-02","LMX1B, MAP2K5","2"]
[null,"Cardiovascular System Development and Function","elongation","elongation of cardiomyocytes","1,54E-02","MAP2K5","1"]
[null,"Cardiovascular System Development and Function","formation","formation of sarcomere","2,19E-02","MAP2K5","1"]
[null,"Cardiovascular System Development and Function","development","development of myocardium","2,40E-02","MAP2K5","1"]
[null,"Cardiovascular System Development and Function","development","development of vasculature","2,84E-02","LMX1B, MAP2K5, SCARB2, TAL1","4"]
[33,"Cardiovascular System Development and Function","maturation","maturation of blood vessel","3,90E-02","FOXO3","1"]
[34,"Connective Tissue Development and Function","quantity","quantity of type IV fibrocyte","2,21E-03","GRID1","1"]
[null,"Connective Tissue Development and Function","lack","lack of ilium","4,41E-03","LMX1B","1"]
[null,"Connective Tissue Development and Function","lack","lack of supraoccipital bone","1,10E-02","LMX1B","1"]
[null,"Connective Tissue Development and Function","lack","lack of ulna","1,32E-02","LMX1B","1"]
[null,"Connective Tissue Development and Function","lack","lack of patella","1,54E-02","LMX1B","1"]
[null,"Connective Tissue Development and Function","abnormal morphology","abnormal morphology of small scapula","6,61E-03","LMX1B","1"]
[null,"Connective Tissue Development and Function","abnormal morphology","abnormal morphology of clavicle","2,62E-02","LMX1B","1"]
[null,"Connective Tissue Development and Function","abnormal morphology","abnormal morphology of fontanelle","2,62E-02","LMX1B","1"]
[35,"Connective Tissue Disorders","Paget's disease of bone","symptomatic stage Paget's disease of bone","2,21E-03","CALCR","1"]
[null,"Connective Tissue Disorders","growth retardation, developmental delay, coarse facies, and early death","growth retardation, developmental delay, coarse facies, and early death","2,21E-03","FTO","1"]
[null,"Connective Tissue Disorders","kyphosis","kyphosis of thoracolumbar spine","2,21E-03","HIP1","1"]
[null,"Connective Tissue Disorders","kyphosis","kyphosis","2,06E-02","HIP1, PARK2","2"]
[null,"Connective Tissue Disorders","damage","damage of red blood cells","4,41E-03","FOXO3","1"]
[null,"Connective Tissue Disorders","damage","damage of connective tissue","1,87E-02","FOXO3, SLC39A8","2"]
[null,"Connective Tissue Disorders","immune complex-mediated inflammatory arthritis","immune complex-mediated inflammatory arthritis","4,41E-03","FOXO3","1"]
[null,"Connective Tissue Disorders","congenital malformation","congenital malformation of face","1,06E-02","FIGN, FTO, TCF7L2","3"]
[null,"Connective Tissue Disorders","degeneration","degeneration of type IV fibrocyte","1,32E-02","GRID1","1"]
[null,"Connective Tissue Disorders","degeneration","degeneration of connective tissue","2,13E-02","GRID1, SLC39A8","2"]
[null,"Connective Tissue Disorders","postmenopausal osteoporosis","postmenopausal osteoporosis","2,62E-02","CALCR","1"]
[null,"Connective Tissue Disorders","erosion","erosion of articular cartilage","3,69E-02","SLC39A8","1"]
[36,"DNA Replication, Recombination, and Repair","DNA damage response","DNA damage response of embryonic cell lines","2,21E-03","KAT8","1"]
[null,"DNA Replication, Recombination, and Repair","DNA damage response","DNA damage response of epithelial cell lines","2,21E-03","KAT8","1"]
[null,"DNA Replication, Recombination, and Repair","DNA damage response","DNA damage response of kidney cell lines","4,41E-03","KAT8","1"]
[null,"DNA Replication, Recombination, and Repair","DNA damage response","DNA damage response of fibroblasts","8,80E-03","KAT8","1"]
[null,"DNA Replication, Recombination, and Repair","quantity","quantity of guanosine","2,21E-03","NT5C2","1"]
[null,"DNA Replication, Recombination, and Repair","quantity","quantity of inosine","6,61E-03","NT5C2","1"]
[null,"DNA Replication, Recombination, and Repair","o-dealkylation","o-dealkylation of DNA","1,54E-02","FTO","1"]
[null,"DNA Replication, Recombination, and Repair","metabolism","metabolism of adenosine","2,83E-02","NT5C2","1"]
[null,"DNA Replication, Recombination, and Repair","repair","repair of DNA","4,34E-02","FOXO3, FTO, KAT8","3"]
[37,"Dermatological Diseases and Conditions","nail-patella syndrome","nail-patella syndrome","2,21E-03","LMX1B","1"]
[null,"Dermatological Diseases and Conditions","quantity","quantity of basal-cell carcinoma","2,21E-03","HHIP","1"]
[null,"Dermatological Diseases and Conditions","skin cancer","skin cancer","4,18E-03","ASB4, CADM2, CALCR, CLIP1, DMXL2, EHBP1, ELAVL4, FOXO3, GNAT2, GRID1, HHIP, LINGO2, LMX1B, NRXN3, PARK2, QPCTL, RABEP1, RASA2, RPTOR, SBK1, SLC39A8, TAL1, USP37, ZC3H4","24"]
[null,"Dermatological Diseases and Conditions","malignant cutaneous melanoma cancer","malignant cutaneous melanoma cancer","1,70E-02","ASB4, CADM2, CALCR, CLIP1, DMXL2, EHBP1, ELAVL4, FOXO3, GNAT2, GRID1, HHIP, LINGO2, LMX1B, NRXN3, QPCTL, RASA2, SBK1, SLC39A8, TAL1, USP37, ZC3H4","21"]
[null,"Dermatological Diseases and Conditions","squamous cell skin cancer","squamous cell skin cancer","3,82E-02","CADM2, FOXO3, HHIP, PARK2, RABEP1, RPTOR","6"]
[38,"Endocrine System Development and Function","abnormal morphology","abnormal morphology of enlarged adenohypophysis","2,21E-03","TCF7L2","1"]
[null,"Endocrine System Development and Function","abnormal morphology","abnormal morphology of intermediate lobe of the pituitary gland","1,32E-02","TCF7L2","1"]
[null,"Endocrine System Development and Function","abnormal morphology","abnormal morphology of enlarged pituitary gland","1,54E-02","TCF7L2","1"]
[null,"Endocrine System Development and Function","area","area of beta islet cells","8,80E-03","TCF7L2","1"]
[null,"Endocrine System Development and Function","glucose tolerance","glucose tolerance","3,43E-02","FOXO3, FTO, TCF7L2","3"]
[null,"Endocrine System Development and Function","quantity","quantity of renin in blood","3,69E-02","KCNK3","1"]
[39,"Gastrointestinal Disease","childhood neuromuscular glycogen storage disease type IV","childhood neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Gastrointestinal Disease","classic hepatic glycogen storage disease type IV","classic hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Gastrointestinal Disease","combined hepatic and myopathic glycogen storage disease type IV","combined hepatic and myopathic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Gastrointestinal Disease","congenital neuromuscular glycogen storage disease type IV","congenital neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Gastrointestinal Disease","fatal perinatal neuromuscular glycogen storage disease type IV","fatal perinatal neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Gastrointestinal Disease","nonprogressive hepatic glycogen storage disease type IV","nonprogressive hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Gastrointestinal Disease","quantity","quantity of adenomatous polyps","6,61E-03","PARK2","1"]
[null,"Gastrointestinal Disease","digestive system cancer","digestive system cancer","7,11E-03","ASB4, CADM2, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GRID1, HHIP, HSD17B12, INO80E, KAT8, KCNK3, LINGO2, LMX1B, MAP2K5, NRXN3, NT5C2, PARK2, RABEP1, RASA2, RPTOR, SBK1, SCARB2, SLC39A8, SMG6, TAL1, TCF7L2, TOMM40, TRIM66, USP37, ZC3H4","38"]
[null,"Gastrointestinal Disease","development","development of intestinal adenoma","8,80E-03","PARK2","1"]
[null,"Gastrointestinal Disease","stage IV colorectal cancer","stage IV colorectal cancer","1,10E-02","RPTOR","1"]
[null,"Gastrointestinal Disease","pancreatic carcinoid tumor","pancreatic carcinoid tumor","1,75E-02","FOXO3","1"]
[null,"Gastrointestinal Disease","susceptibility to type 2 diabetes mellitus","susceptibility to type 2 diabetes mellitus","2,83E-02","TCF7L2","1"]
[null,"Gastrointestinal Disease","gastrointestinal tract cancer","gastrointestinal tract cancer","3,89E-02","ASB4, CALCR, CCDC171, CLIP1, DMXL2, EHBP1, ELAVL4, ETV5, FIGN, FOXO3, FTO, GBE1, GRID1, HHIP, HSD17B12, INO80E, LINGO2, MAP2K5, NRXN3, NT5C2, PARK2, RABEP1, RASA2, RPTOR, SCARB2, SLC39A8, SMG6, TCF7L2, TOMM40, TRIM66, ZC3H4","31"]
[null,"Gastrointestinal Disease","gestational diabetes mellitus","gestational diabetes mellitus","4,11E-02","TCF7L2","1"]
[40,"Hereditary Disorder","achromatopsia type 4","achromatopsia type 4","2,21E-03","GNAT2","1"]
[null,"Hereditary Disorder","adult polyglucosan body disease","adult polyglucosan body disease","2,21E-03","GBE1","1"]
[null,"Hereditary Disorder","autosomal recessive juvenile Parkinson disease type 2","autosomal recessive juvenile Parkinson disease type 2","2,21E-03","PARK2","1"]
[null,"Hereditary Disorder","autosomal recessive spastic paraplegia type 45","autosomal recessive spastic paraplegia type 45","2,21E-03","NT5C2","1"]
[null,"Hereditary Disorder","childhood neuromuscular glycogen storage disease type IV","childhood neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hereditary Disorder","classic hepatic glycogen storage disease type IV","classic hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hereditary Disorder","combined hepatic and myopathic glycogen storage disease type IV","combined hepatic and myopathic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hereditary Disorder","congenital neuromuscular glycogen storage disease type IV","congenital neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hereditary Disorder","fatal perinatal neuromuscular glycogen storage disease type IV","fatal perinatal neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hereditary Disorder","growth retardation, developmental delay, coarse facies, and early death","growth retardation, developmental delay, coarse facies, and early death","2,21E-03","FTO","1"]
[null,"Hereditary Disorder","hereditary prostate cancer 12","hereditary prostate cancer 12","2,21E-03","EHBP1","1"]
[null,"Hereditary Disorder","nail-patella syndrome","nail-patella syndrome","2,21E-03","LMX1B","1"]
[null,"Hereditary Disorder","nonprogressive hepatic glycogen storage disease type IV","nonprogressive hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hereditary Disorder","primary pulmonary hypertension 4","primary pulmonary hypertension 4","2,21E-03","KCNK3","1"]
[null,"Hereditary Disorder","progressive myoclonic epilepsy type 4 without renal failure","progressive myoclonic epilepsy type 4 without renal failure","2,21E-03","SCARB2","1"]
[null,"Hereditary Disorder","progressive myoclonic epilepsy type 4 with renal failure","progressive myoclonic epilepsy type 4 with renal failure","4,41E-03","SCARB2","1"]
[null,"Hereditary Disorder","Parkinson's disease","autosomal dominant Parkinson's disease","1,97E-02","PARK2","1"]
[null,"Hereditary Disorder","encephalopathy","autosomal dominant encephalopathy","2,37E-02","GNAT2, PARK2","2"]
[null,"Hereditary Disorder","inborn error of carbohydrate metabolism","inborn error of carbohydrate metabolism","3,39E-02","GBE1, SLC39A8","2"]
[41,"Immune Cell Trafficking","accumulation","accumulation of memory precursor T lymphocytes","2,21E-03","FOXO3","1"]
[null,"Immune Cell Trafficking","accumulation","accumulation of T lymphocytes","2,63E-02","FOXO3, TAL1","2"]
[null,"Immune Cell Trafficking","hyperactivation","hyperactivation of helper T lymphocytes","2,21E-03","FOXO3","1"]
[null,"Immune Cell Trafficking","migration","migration of Langerhans cells","4,33E-02","RPTOR","1"]
[42,"Inflammatory Response","accumulation","accumulation of memory precursor T lymphocytes","2,21E-03","FOXO3","1"]
[null,"Inflammatory Response","accumulation","accumulation of T lymphocytes","2,63E-02","FOXO3, TAL1","2"]
[null,"Inflammatory Response","hyperactivation","hyperactivation of helper T lymphocytes","2,21E-03","FOXO3","1"]
[null,"Inflammatory Response","polyploidization","polyploidization of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Inflammatory Response","proliferation","proliferation of bone-marrow-derived monocyte/macrophage precursor cells","2,21E-03","TAL1","1"]
[null,"Inflammatory Response","proliferation","proliferation of promegakaryocytes","2,21E-03","TAL1","1"]
[null,"Inflammatory Response","quantity","quantity of spleen-derived dendritic cells","2,21E-03","RPTOR","1"]
[null,"Inflammatory Response","quantity","quantity of mast precursor cells","4,41E-03","TAL1","1"]
[null,"Inflammatory Response","size","size of Langerhans cells","2,21E-03","RPTOR","1"]
[null,"Inflammatory Response","immune complex-mediated inflammatory arthritis","immune complex-mediated inflammatory arthritis","4,41E-03","FOXO3","1"]
[null,"Inflammatory Response","turnover","turnover of Langerhans cells","4,41E-03","RPTOR","1"]
[null,"Inflammatory Response","Sjogren's-syndrome like inflammation","Sjogren's-syndrome like inflammation","6,61E-03","FOXO3","1"]
[null,"Inflammatory Response","memory T cell response","memory T cell response","2,19E-02","FOXO3","1"]
[null,"Inflammatory Response","phagocytosis","phagocytosis of macrophage cancer cell lines","2,62E-02","CLIP1","1"]
[null,"Inflammatory Response","migration","migration of Langerhans cells","4,33E-02","RPTOR","1"]
[43,"Lipid Metabolism","activation","activation of paclitaxel","2,21E-03","CLIP1","1"]
[null,"Lipid Metabolism","binding","binding of phosphatidylinositol 3,5-diphosphate","6,61E-03","HIP1","1"]
[null,"Lipid Metabolism","binding","binding of phosphatidylinositol 3,4-diphosphate","8,80E-03","HIP1","1"]
[null,"Lipid Metabolism","binding","binding of phosphatidylinositol-3-phosphate","8,80E-03","HIP1","1"]
[null,"Lipid Metabolism","quantity","quantity of steroid","4,31E-02","FOXO3, KCNK3, RPTOR, TCF7L2","4"]
[null,"Lipid Metabolism","concentration","concentration of cholesterol","4,43E-02","FOXO3, RPTOR, TCF7L2","3"]
[44,"Metabolic Disease","Paget's disease of bone","symptomatic stage Paget's disease of bone","2,21E-03","CALCR","1"]
[null,"Metabolic Disease","adult polyglucosan body disease","adult polyglucosan body disease","2,21E-03","GBE1","1"]
[null,"Metabolic Disease","childhood neuromuscular glycogen storage disease type IV","childhood neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Metabolic Disease","classic hepatic glycogen storage disease type IV","classic hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Metabolic Disease","combined hepatic and myopathic glycogen storage disease type IV","combined hepatic and myopathic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Metabolic Disease","congenital neuromuscular glycogen storage disease type IV","congenital neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Metabolic Disease","fatal perinatal neuromuscular glycogen storage disease type IV","fatal perinatal neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Metabolic Disease","nonprogressive hepatic glycogen storage disease type IV","nonprogressive hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Metabolic Disease","fasting hypoglycemia","fasting hypoglycemia","6,61E-03","FOXO3","1"]
[null,"Metabolic Disease","hypercholesterolemia","Hypercholesterolemia","9,08E-03","FOXO3, RPTOR","2"]
[null,"Metabolic Disease","hypokalemia","hypokalemia","2,83E-02","KCNK3","1"]
[null,"Metabolic Disease","susceptibility to type 2 diabetes mellitus","susceptibility to type 2 diabetes mellitus","2,83E-02","TCF7L2","1"]
[null,"Metabolic Disease","hypoglycemia","hypoglycemia","3,07E-02","FOXO3, TCF7L2","2"]
[null,"Metabolic Disease","inborn error of carbohydrate metabolism","inborn error of carbohydrate metabolism","3,39E-02","GBE1, SLC39A8","2"]
[null,"Metabolic Disease","gestational diabetes mellitus","gestational diabetes mellitus","4,11E-02","TCF7L2","1"]
[null,"Molecular Transport","influx","influx of Zn2+","2,21E-03","SLC39A8","1"]
[45,"Molecular Transport","quantity","quantity of guanosine","2,21E-03","NT5C2","1"]
[null,"Molecular Transport","quantity","quantity of inosine","6,61E-03","NT5C2","1"]
[null,"Molecular Transport","quantity","quantity of nitrate","1,54E-02","PARK2","1"]
[null,"Molecular Transport","quantity","quantity of glycogen","2,21E-02","GBE1, RPTOR","2"]
[null,"Molecular Transport","quantity","quantity of nitrite","3,26E-02","PARK2","1"]
[null,"Molecular Transport","quantity","quantity of renin in blood","3,69E-02","KCNK3","1"]
[null,"Molecular Transport","quantity","quantity of steroid","4,31E-02","FOXO3, KCNK3, RPTOR, TCF7L2","4"]
[null,"Molecular Transport","transport","transport of Co2+","1,10E-02","SLC39A8","1"]
[null,"Molecular Transport","transport","transport of Zn2+","3,69E-02","SLC39A8","1"]
[null,"Molecular Transport","receptor-mediated endocytosis","receptor-mediated endocytosis of protein","1,54E-02","HIP1","1"]
[null,"Molecular Transport","release","release of lactic acid","1,97E-02","NT5C2","1"]
[null,"Molecular Transport","internalization","internalization of protein","2,25E-02","HIP1, TOMM40","2"]
[null,"Molecular Transport","abnormal quantity","abnormal quantity of dopamine","3,26E-02","PARK2","1"]
[null,"Molecular Transport","concentration","concentration of cholesterol","4,43E-02","FOXO3, RPTOR, TCF7L2","3"]
[46,"Ophthalmic Disease","achromatopsia type 4","achromatopsia type 4","2,21E-03","GNAT2","1"]
[null,"Ophthalmic Disease","hypoplasia","hypoplasia of iris stroma","4,41E-03","LMX1B","1"]
[null,"Ophthalmic Disease","microphthalmia","microphthalmia","1,87E-02","HIP1, LMX1B","2"]
[47,"Post-Translational Modification","peroxidation","peroxidation of protein","2,21E-03","PARK2","1"]
[null,"Post-Translational Modification","autoubiquitination","autoubiquitination of protein","5,46E-03","ASB4, PARK2","2"]
[48,"Psychological Disorders","autosomal recessive juvenile Parkinson disease type 2","autosomal recessive juvenile Parkinson disease type 2","2,21E-03","PARK2","1"]
[null,"Psychological Disorders","pervasive developmental disorder","pervasive developmental disorder","1,29E-02","EHBP1, MAP2K5, TCF7L2","3"]
[null,"Psychological Disorders","Parkinson's disease","autosomal dominant Parkinson's disease","1,97E-02","PARK2","1"]
[null,"Psychological Disorders","Parkinson's disease","Parkinson's disease","2,84E-02","PARK2, SCARB2, USP37","3"]
[null,"Psychological Disorders","disorder of basal ganglia","disorder of basal ganglia","2,44E-02","ETV5, FOXO3, GNAT2, PARK2, SCARB2, USP37","6"]
[null,"Psychological Disorders","bipolar disorder","bipolar disorder","2,97E-02","GRID1, LINC00907, TOMM40","3"]
[null,"Psychological Disorders","late-onset Parkinson disease","late-onset Parkinson disease","3,48E-02","PARK2","1"]
[49,"Renal and Urological Disease","dysplasia","dysplasia of podocytes","2,21E-03","LMX1B","1"]
[null,"Renal and Urological Disease","progressive myoclonic epilepsy type 4 with renal failure","progressive myoclonic epilepsy type 4 with renal failure","4,41E-03","SCARB2","1"]
[null,"Renal and Urological Disease","urinary tract cancer","urinary tract cancer","4,26E-02","CADM2, CLIP1, FIGN, FOXO3, GBE1, MAP2K5, NT5C2, SLC39A8, ZC3H4","9"]
[50,"Renal and Urological System Development and Function","development","development of podocytes","2,21E-03","LMX1B","1"]
[null,"Renal and Urological System Development and Function","outgrowth","outgrowth of glomerular capillary","2,21E-03","LMX1B","1"]
[null,"Renal and Urological System Development and Function","quantity","quantity of pedicels","2,21E-03","LMX1B","1"]
[null,"Renal and Urological System Development and Function","quantity","quantity of podocyte slit diaphragm","4,41E-03","LMX1B","1"]
[null,"Renal and Urological System Development and Function","formation","formation of pedicels","4,41E-03","LMX1B","1"]
[null,"Renal and Urological System Development and Function","formation","formation of podocyte slit diaphragm","4,41E-03","LMX1B","1"]
[null,"Renal and Urological System Development and Function","differentiation","differentiation of podocytes","6,61E-03","LMX1B","1"]
[null,"Renal and Urological System Development and Function","mitosis","arrest in mitosis of kidney cell lines","6,61E-03","CLIP1","1"]
[null,"Renal and Urological System Development and Function","lack","lack of podocyte slit diaphragm","1,10E-02","LMX1B","1"]
[null,"Renal and Urological System Development and Function","lack","lack of pedicels","1,32E-02","LMX1B","1"]
[null,"Renal and Urological System Development and Function","abnormal morphology","abnormal morphology of pedicels","1,54E-02","LMX1B","1"]
[null,"Renal and Urological System Development and Function","abnormal morphology","abnormal morphology of urothelium","1,54E-02","SCARB2","1"]
[null,"Renal and Urological System Development and Function","G2 phase","arrest in G2 phase of kidney cell lines","2,40E-02","CALCR","1"]
[51,"Reproductive System Development and Function","growth","initiation of growth of primordial ovarian follicle","2,21E-03","FOXO3","1"]
[null,"Reproductive System Development and Function","growth","growth of atretic ovarian follicle","6,61E-03","FOXO3","1"]
[null,"Reproductive System Development and Function","development","development of sperm head","4,41E-03","CLIP1","1"]
[null,"Reproductive System Development and Function","cell division","cell division of male germ cells","6,61E-03","ETV5","1"]
[null,"Reproductive System Development and Function","abnormal morphology","abnormal morphology of germ cells","9,24E-03","ETV5, FOXO3, HIP1","3"]
[null,"Reproductive System Development and Function","abnormal morphology","abnormal morphology of enlarged ovary","1,32E-02","FOXO3","1"]
[null,"Reproductive System Development and Function","abnormal morphology","abnormal morphology of male germ cells","2,89E-02","ETV5, HIP1","2"]
[null,"Reproductive System Development and Function","abnormal morphology","abnormal morphology of spermatogonia","4,54E-02","ETV5","1"]
[null,"Reproductive System Development and Function","mounting","mounting","1,32E-02","LMX1B","1"]
[null,"Reproductive System Development and Function","proliferation","proliferation of gonadal cells","1,62E-02","ETV5, FOXO3","2"]
[null,"Reproductive System Development and Function","proliferation","proliferation of spermatogonia","3,48E-02","ETV5","1"]
[null,"Reproductive System Development and Function","premature senescence","premature senescence of reproductive system","3,05E-02","FOXO3","1"]
[null,"Reproductive System Development and Function","spermiation","spermiation","3,48E-02","ETV5","1"]
[null,"Reproductive System Development and Function","morphology","morphology of breast cell lines","4,33E-02","FOXO3","1"]
[52,"Reproductive System Disease","hereditary prostate cancer 12","hereditary prostate cancer 12","2,21E-03","EHBP1","1"]
[null,"Reproductive System Disease","ovarian teratoma","ovarian teratoma","8,80E-03","FOXO3","1"]
[null,"Reproductive System Disease","tumorigenesis","tumorigenesis of prostatic adenocarcinoma","1,10E-02","HIP1","1"]
[null,"Reproductive System Disease","metastasis","metastasis of cervical cancer cell lines","1,32E-02","RPTOR","1"]
[null,"Reproductive System Disease","prolactinoma","prolactinoma","2,19E-02","FOXO3","1"]
[null,"Reproductive System Disease","prostate cancer","prostate cancer","2,46E-02","CALCR, DMXL2, EHBP1, ETV5, HIP1, MTCH2, NRXN3, RPTOR","8"]
[null,"Reproductive System Disease","hyperplasia","hyperplasia of pituitary gland","3,26E-02","TCF7L2","1"]
[null,"Reproductive System Disease","prostatic carcinoma","prostatic carcinoma","3,89E-02","CALCR, DMXL2, HIP1, MTCH2, NRXN3, RPTOR","6"]
[53,"Skeletal and Muscular Disorders","Paget's disease of bone","symptomatic stage Paget's disease of bone","2,21E-03","CALCR","1"]
[null,"Skeletal and Muscular Disorders","autosomal recessive juvenile Parkinson disease type 2","autosomal recessive juvenile Parkinson disease type 2","2,21E-03","PARK2","1"]
[null,"Skeletal and Muscular Disorders","bilateral hyperpronation","bilateral hyperpronation","2,21E-03","TCF7L2","1"]
[null,"Skeletal and Muscular Disorders","growth retardation, developmental delay, coarse facies, and early death","growth retardation, developmental delay, coarse facies, and early death","2,21E-03","FTO","1"]
[null,"Skeletal and Muscular Disorders","kyphosis","kyphosis of thoracolumbar spine","2,21E-03","HIP1","1"]
[null,"Skeletal and Muscular Disorders","kyphosis","kyphosis","2,06E-02","HIP1, PARK2","2"]
[null,"Skeletal and Muscular Disorders","nail-patella syndrome","nail-patella syndrome","2,21E-03","LMX1B","1"]
[null,"Skeletal and Muscular Disorders","immune complex-mediated inflammatory arthritis","immune complex-mediated inflammatory arthritis","4,41E-03","FOXO3","1"]
[null,"Skeletal and Muscular Disorders","hyperplasia","hyperplasia of neointimal cells","6,61E-03","FOXO3","1"]
[null,"Skeletal and Muscular Disorders","motor dysfunction","progressive motor dysfunction","8,80E-03","PARK2","1"]
[null,"Skeletal and Muscular Disorders","congenital anomaly of limb","congenital anomaly of limb","8,99E-03","ETV5, LMX1B, TCF7L2","3"]
[null,"Skeletal and Muscular Disorders","congenital malformation","congenital malformation of face","1,06E-02","FIGN, FTO, TCF7L2","3"]
[null,"Skeletal and Muscular Disorders","tremor","tremor of limb","1,10E-02","PARK2","1"]
[null,"Skeletal and Muscular Disorders","atrophy","atrophy of myotube","1,54E-02","FOXO3","1"]
[null,"Skeletal and Muscular Disorders","atrophy","atrophy of myofiber","3,48E-02","FOXO3","1"]
[null,"Skeletal and Muscular Disorders","cell death","cell death of cardiomyocytes","1,72E-02","FOXO3, MAP2K5, PARK2","3"]
[null,"Skeletal and Muscular Disorders","sensorimotor impairment","sensorimotor impairment","1,75E-02","PARK2","1"]
[null,"Skeletal and Muscular Disorders","Parkinson's disease","autosomal dominant Parkinson's disease","1,97E-02","PARK2","1"]
[null,"Skeletal and Muscular Disorders","Parkinson's disease","Parkinson's disease","2,84E-02","PARK2, SCARB2, USP37","3"]
[null,"Skeletal and Muscular Disorders","hypertrophy","hypertrophy of myofiber","2,19E-02","FOXO3","1"]
[null,"Skeletal and Muscular Disorders","hypertrophy","hypertrophy of cardiomyocytes","4,23E-02","FOXO3, MAP2K5","2"]
[null,"Skeletal and Muscular Disorders","necrosis","necrosis of skeletal muscle cells","2,19E-02","PARK2","1"]
[null,"Skeletal and Muscular Disorders","postmenopausal osteoporosis","postmenopausal osteoporosis","2,62E-02","CALCR","1"]
[null,"Skeletal and Muscular Disorders","embryonal rhabdomyosarcoma","embryonal rhabdomyosarcoma","2,66E-02","ASB4, CALCR, DMXL2, GBE1, PARK2, SLC39A8","6"]
[null,"Skeletal and Muscular Disorders","late-onset Parkinson disease","late-onset Parkinson disease","3,48E-02","PARK2","1"]
[null,"Skeletal and Muscular Disorders","ventricular fibrillation","recurrent ventricular fibrillation","3,48E-02","KCNK3","1"]
[null,"Skeletal and Muscular Disorders","erosion","erosion of articular cartilage","3,69E-02","SLC39A8","1"]
[54,"Behavior","locomotion","locomotion","2,63E-03","ELAVL4, ETV5, LMX1B, PARK2, TAL1","5"]
[null,"Behavior","mounting","mounting","1,32E-02","LMX1B","1"]
[null,"Behavior","social behavior","social behavior","2,13E-02","GRID1, NRXN3","2"]
[null,"Behavior","behavior","behavior","3,00E-02","ELAVL4, FTO, GRID1, LMX1B, NRXN3, PARK2, SCARB2","7"]
[55,"Carbohydrate Metabolism","metabolism","metabolism of glycogen","4,06E-03","GBE1, TCF7L2","2"]
[null,"Carbohydrate Metabolism","binding","binding of phosphatidylinositol 3,5-diphosphate","6,61E-03","HIP1","1"]
[null,"Carbohydrate Metabolism","binding","binding of phosphatidylinositol 3,4-diphosphate","8,80E-03","HIP1","1"]
[null,"Carbohydrate Metabolism","binding","binding of phosphatidylinositol-3-phosphate","8,80E-03","HIP1","1"]
[null,"Carbohydrate Metabolism","incorporation","incorporation of glycogen","1,32E-02","NT5C2","1"]
[null,"Carbohydrate Metabolism","incorporation","incorporation of D-glucose","3,26E-02","NT5C2","1"]
[null,"Carbohydrate Metabolism","glycolysis","glycolysis of lung cancer cell lines","1,54E-02","PARK2","1"]
[null,"Carbohydrate Metabolism","quantity","quantity of carbohydrate","1,72E-02","FOXO3, GBE1, RPTOR, SCARB2, TCF7L2","5"]
[null,"Carbohydrate Metabolism","quantity","quantity of glycogen","2,21E-02","GBE1, RPTOR","2"]
[null,"Carbohydrate Metabolism","homeostasis","homeostasis of D-glucose","1,85E-02","FOXO3, GBE1, TCF7L2","3"]
[null,"Carbohydrate Metabolism","synthesis","synthesis of heparan sulfate proteoglycan","3,05E-02","TCF7L2","1"]
[56,"Drug Metabolism","inactivation","inactivation of cytarabine","4,41E-03","NT5C2","1"]
[null,"Drug Metabolism","catabolism","catabolism of dopamine","1,32E-02","PARK2","1"]
[null,"Drug Metabolism","metabolism","metabolism of norepinephrine","2,40E-02","PARK2","1"]
[null,"Drug Metabolism","abnormal quantity","abnormal quantity of dopamine","3,26E-02","PARK2","1"]
[57,"Inflammatory Disease","immune complex-mediated inflammatory arthritis","immune complex-mediated inflammatory arthritis","4,41E-03","FOXO3","1"]
[null,"Inflammatory Disease","inflammatory pain","inflammatory pain","2,40E-02","LMX1B","1"]
[58,"Organismal Survival","thriving","thriving of mice","4,41E-03","HIP1","1"]
[null,"Organismal Survival","organismal death","organismal death","1,23E-02","CALCR, ELAVL4, FOXO3, FTO, GBE1, HIP1, KAT8, LMX1B, MAP2K5, PARK2, RPTOR, SCARB2, TAL1, TCF7L2","14"]
[null,"Organismal Survival","thermosensitivity","thermosensitivity","1,54E-02","LMX1B","1"]
[null,"Organismal Survival","perinatal death","perinatal death","2,71E-02","ELAVL4, GBE1, HIP1, LMX1B, TCF7L2","5"]
[59,"RNA Damage and Repair","repair","repair of RNA","4,41E-03","FTO","1"]
[null,"RNA Damage and Repair","stabilization","stabilization of mRNA","4,84E-03","CALCR, ELAVL4","2"]
[60,"RNA Post-Transcriptional Modification","repair","repair of RNA","4,41E-03","FTO","1"]
[null,"RNA Post-Transcriptional Modification","stabilization","stabilization of mRNA","4,84E-03","CALCR, ELAVL4","2"]
[61,"Skeletal and Muscular System Development and Function","lack","lack of ilium","4,41E-03","LMX1B","1"]
[null,"Skeletal and Muscular System Development and Function","lack","lack of supraoccipital bone","1,10E-02","LMX1B","1"]
[null,"Skeletal and Muscular System Development and Function","lack","lack of ulna","1,32E-02","LMX1B","1"]
[null,"Skeletal and Muscular System Development and Function","lack","lack of patella","1,54E-02","LMX1B","1"]
[null,"Skeletal and Muscular System Development and Function","abnormal morphology","abnormal morphology of small scapula","6,61E-03","LMX1B","1"]
[null,"Skeletal and Muscular System Development and Function","abnormal morphology","abnormal morphology of clavicle","2,62E-02","LMX1B","1"]
[null,"Skeletal and Muscular System Development and Function","abnormal morphology","abnormal morphology of fontanelle","2,62E-02","LMX1B","1"]
[null,"Skeletal and Muscular System Development and Function","elongation","elongation of cardiomyocytes","1,54E-02","MAP2K5","1"]
[null,"Skeletal and Muscular System Development and Function","sensorimotor integration","sensorimotor integration","1,54E-02","PARK2","1"]
[null,"Skeletal and Muscular System Development and Function","formation","formation of sarcomere","2,19E-02","MAP2K5","1"]
[null,"Skeletal and Muscular System Development and Function","development","development of myocardium","2,40E-02","MAP2K5","1"]
[null,"Skeletal and Muscular System Development and Function","cell viability","cell viability of vascular smooth muscle cells","2,83E-02","FOXO3","1"]
[null,"Skeletal and Muscular System Development and Function","size","size of muscle cells","3,78E-02","FOXO3, SCARB2","2"]
[62,"Gene Expression","stabilization","stabilization of mRNA","4,84E-03","CALCR, ELAVL4","2"]
[null,"Gene Expression","transcription","transcription of RNA","2,28E-02","ETV5, FOXO3, HIP1, KAT8, LMX1B, MAP2K5, MTCH2, PARK2, TAL1, TCF7L2, TRIM66","11"]
[null,"Gene Expression","transcription","transcription of DNA","4,05E-02","ETV5, FOXO3, KAT8, LMX1B, MAP2K5, PARK2, TAL1, TCF7L2, TRIM66","9"]
[null,"Gene Expression","expression","expression of RNA","3,29E-02","CALCR, ETV5, FOXO3, HIP1, KAT8, LMX1B, MAP2K5, MTCH2, PARK2, TAL1, TCF7L2, TRIM66","12"]
[63,"Endocrine System Disorders","fasting hypoglycemia","fasting hypoglycemia","6,61E-03","FOXO3","1"]
[null,"Endocrine System Disorders","ovarian teratoma","ovarian teratoma","8,80E-03","FOXO3","1"]
[null,"Endocrine System Disorders","pancreatic carcinoid tumor","pancreatic carcinoid tumor","1,75E-02","FOXO3","1"]
[null,"Endocrine System Disorders","prolactinoma","prolactinoma","2,19E-02","FOXO3","1"]
[null,"Endocrine System Disorders","susceptibility to type 2 diabetes mellitus","susceptibility to type 2 diabetes mellitus","2,83E-02","TCF7L2","1"]
[null,"Endocrine System Disorders","hypoglycemia","hypoglycemia","3,07E-02","FOXO3, TCF7L2","2"]
[null,"Endocrine System Disorders","hyperplasia","hyperplasia of pituitary gland","3,26E-02","TCF7L2","1"]
[null,"Endocrine System Disorders","gestational diabetes mellitus","gestational diabetes mellitus","4,11E-02","TCF7L2","1"]
[64,"Hair and Skin Development and Function","mitosis","arrest in mitosis of epithelial cell lines","6,61E-03","CLIP1","1"]
[null,"Hair and Skin Development and Function","G2 phase","arrest in G2 phase of epithelial cell lines","2,83E-02","CALCR","1"]
[65,"Respiratory System Development and Function","cell cycle progression","re-entry into cell cycle progression of lung cell lines","6,61E-03","FOXO3","1"]
[null,"Respiratory System Development and Function","function","function of respiratory system","8,81E-03","FTO, PARK2","2"]
[66,"Tumor Morphology","quantity","quantity of carcinoma cells","6,61E-03","FOXO3","1"]
[null,"Tumor Morphology","progression","progression of adenoma","8,80E-03","FOXO3","1"]
[null,"Tumor Morphology","apoptosis","apoptosis of medulloblastoma cells","1,10E-02","MAP2K5","1"]
[null,"Tumor Morphology","invasion","invasion of prostate cancer cells","1,75E-02","MAP2K5","1"]
[null,"Tumor Morphology","invasion","invasion of cancer cells","2,71E-02","FOXO3, MAP2K5","2"]
[null,"Tumor Morphology","proliferation","proliferation of multiple myeloma cells","3,05E-02","TCF7L2","1"]
[67,"Visual System Development and Function","formation","formation of eye","7,78E-03","FTO, GNAT2, HHIP, HIP1, LMX1B","5"]
[null,"Visual System Development and Function","abnormal morphology","abnormal morphology of iris stroma","8,80E-03","LMX1B","1"]
[null,"Visual System Development and Function","abnormal morphology","abnormal morphology of ciliary body","1,75E-02","LMX1B","1"]
[null,"Visual System Development and Function","abnormal morphology","abnormal morphology of pupil","1,75E-02","LMX1B","1"]
[null,"Visual System Development and Function","abnormal morphology","abnormal morphology of anterior segment of the eye","2,54E-02","HIP1, LMX1B","2"]
[null,"Visual System Development and Function","abnormal morphology","abnormal morphology of anterior chamber of eye","3,05E-02","LMX1B","1"]
[null,"Visual System Development and Function","abnormal morphology","abnormal morphology of corneal stroma","3,90E-02","LMX1B","1"]
[null,"Visual System Development and Function","development","development of retina","2,42E-02","GNAT2, HHIP","2"]
[null,"Visual System Development and Function","development","development of retinal cone cells","3,05E-02","GNAT2","1"]
[68,"Cell Signaling","synthesis","synthesis of GTP","8,80E-03","NT5C2","1"]
[null,"Cell Signaling","G-protein signaling, coupled to cyclic nucleotide second messenger","G-protein signaling, coupled to cyclic nucleotide second messenger","1,48E-02","CALCR, GNAT2","2"]
[null,"Cell Signaling","G-protein signaling, coupled to cGMP nucleotide second messenger","G-protein signaling, coupled to cGMP nucleotide second messenger","1,75E-02","GNAT2","1"]
[null,"Cell Signaling","elevation","elevation of Ca2+ in cytosol","4,33E-02","CALCR, GNAT2","2"]
[69,"Organismal Functions","grasping","grasping","1,16E-02","ELAVL4, SCARB2","2"]
[null,"Organismal Functions","glycemic control","glycemic control","3,26E-02","TCF7L2","1"]
[70,"Protein Trafficking","receptor-mediated endocytosis","receptor-mediated endocytosis of protein","1,54E-02","HIP1","1"]
[null,"Protein Trafficking","internalization","internalization of protein","2,25E-02","HIP1, TOMM40","2"]
[null,"Protein Trafficking","targeting","targeting of protein","3,88E-02","SCARB2, TOMM40","2"]
[71,"Energy Production","synthesis","synthesis of ATP","1,87E-02","FOXO3, PARK2","2"]
[72,"Nutritional Disease","body mass index","body mass index","2,54E-02","FTO, TCF7L2","2"]
[null,"Nutritional Disease","early-onset morbid obesity","early-onset morbid obesity","2,62E-02","FTO","1"]
[73,"Protein Synthesis","formation","formation of aggresome","3,48E-02","PARK2","1"]
[null,"Protein Synthesis","quantity","quantity of renin in blood","3,69E-02","KCNK3","1"]
[74,"Vitamin and Mineral Metabolism","elevation","elevation of Ca2+ in cytosol","4,33E-02","CALCR, GNAT2","2"]
[]
["Pathways based on only 1 gene"]
[1,"Infectious Diseases","infection","infection of spleen","4,11E-02","PARK2","1"]
[null,"Infectious Diseases","listeriosis","listeriosis","4,33E-02","PARK2","1"]
[2,"Humoral Immune Response","differentiation","differentiation of B-2 lymphocytes","6,61E-03","TAL1","1"]
[null,"Humoral Immune Response","differentiation","differentiation of marginal-zone B lymphocytes","6,61E-03","TAL1","1"]
[null,"Humoral Immune Response","differentiation","differentiation of transitional 1 B lymphocytes","6,61E-03","TAL1","1"]
[null,"Humoral Immune Response","production","production of follicular B lymphocytes","1,10E-02","TAL1","1"]
[null,"Humoral Immune Response","commitment","commitment of B lymphocytes","1,32E-02","TAL1","1"]
[null,"Humoral Immune Response","development","development of follicular B lymphocytes","4,54E-02","TAL1","1"]
[3,"Auditory and Vestibular System Development and Function","function","function of vestibular hair cells","6,61E-03","SCARB2","1"]
[null,"Auditory and Vestibular System Development and Function","abnormal morphology","abnormal morphology of otolithic membrane","1,10E-02","SCARB2","1"]
[null,"Auditory and Vestibular System Development and Function","abnormal morphology","abnormal morphology of marginal stria vascularis cells","1,54E-02","SCARB2","1"]
[null,"Auditory and Vestibular System Development and Function","lack","lack of otoliths","1,54E-02","SCARB2","1"]
[4,"Free Radical Scavenging","scavenging","scavenging of hydrogen peroxide","4,41E-03","FOXO3","1"]
[null,"Free Radical Scavenging","hyperproduction","hyperproduction of reactive oxygen species","8,80E-03","FOXO3","1"]
[5,"Hypersensitivity Response","quantity","quantity of mast precursor cells","4,41E-03","TAL1","1"]
[6,"Respiratory Disease","primary pulmonary hypertension 4","primary pulmonary hypertension 4","2,21E-03","KCNK3","1"]
[null,"Respiratory Disease","hypercapnia","hypercapnia","8,80E-03","KCNK3","1"]
[7,"Protein Degradation","peroxidation","peroxidation of protein","2,21E-03","PARK2","1"]
[null,"Protein Degradation","formation","formation of aggresome","3,48E-02","PARK2","1"]
[8,"Hepatic System Disease","childhood neuromuscular glycogen storage disease type IV","childhood neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hepatic System Disease","classic hepatic glycogen storage disease type IV","classic hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hepatic System Disease","combined hepatic and myopathic glycogen storage disease type IV","combined hepatic and myopathic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hepatic System Disease","congenital neuromuscular glycogen storage disease type IV","congenital neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hepatic System Disease","fatal perinatal neuromuscular glycogen storage disease type IV","fatal perinatal neuromuscular glycogen storage disease type IV","2,21E-03","GBE1","1"]
[null,"Hepatic System Disease","nonprogressive hepatic glycogen storage disease type IV","nonprogressive hepatic glycogen storage disease type IV","2,21E-03","GBE1","1"]
[9,"Digestive System Development and Function","closure","closure of palate","2,21E-03","TCF7L2","1"]
[null,"Digestive System Development and Function","quantity","quantity of enterocytes","6,61E-03","TCF7L2","1"]
[null,"Digestive System Development and Function","abnormal morphology","abnormal morphology of enterocytes","2,62E-02","TCF7L2","1"]
[null,"Digestive System Development and Function","morphogenesis","morphogenesis of embryonic gastrointestinal tract","4,33E-02","TCF7L2","1"]