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["ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"]
["GO:1901214","regulation of neuron death","47/267","321/18866",5.23727386722484e-34,1.61659146328032e-30,5.79039897143001e-31,"GCLC/TNFRSF1B/GRN/ERBB3/HDAC4/GSK3B/REST/BAX/SIRT1/HIF1A/ADNP/FGF8/CCL2/PPARGC1A/IFNG/SOD2/CREB1/PTK2B/PIK3CA/ATF4/APOE/KRAS/NGF/IL10/TP53/SOD1/AKT1/NTRK2/PRKCI/CDK5/CTNNB1/GDNF/MECP2/FOS/BCL2L1/BCL2/SNCG/BDNF/JUN/NQO1/PRKN/MAPT/DCC/LRRK2/NF1/MTOR/TNF",47]
["GO:0070997","neuron death","49/267","360/18866",6.47543145716129e-34,1.61659146328032e-30,5.79039897143001e-31,"GCLC/TNFRSF1B/GRN/NGFR/ERBB3/HDAC4/GSK3B/REST/BAX/SIRT1/HIF1A/ADNP/FGF8/CCL2/PPARGC1A/IFNG/SOD2/CREB1/PTK2B/PIK3CA/ATF4/APOE/KRAS/NGF/IL10/TP53/SOD1/AKT1/NTRK2/PRKCI/CDK5/CTNNB1/FADD/GDNF/MECP2/FOS/BCL2L1/BCL2/SNCG/BDNF/JUN/NQO1/PRKN/MAPT/DCC/LRRK2/NF1/MTOR/TNF",49]
["GO:0042493","response to drug","48/267","397/18866",8.33432501197159e-31,1.38710949282581e-27,4.96842743696131e-28,"CD38/NOS2/HDAC4/PTGS2/REST/ABCB1/GNAS/P2RX7/COMT/CYP2D6/TSPO/HTR2A/SFRP1/FGF8/COL1A1/PPARGC1A/KMT2A/CREB1/PTK2B/IL1B/CYP2E1/LDHA/IL10/ADAM10/DUSP6/CYP1A2/TP53/SOD1/SLC6A3/SRD5A1/DRD2/SST/CYP3A4/DVL3/RET/CYP2C19/CTNNB1/FOS/BCL2/PTEN/LPL/BDNF/MTHFR/TGIF1/ADIPOQ/PTCH1/HDAC2/CYP2B6",48]
["GO:0006979","response to oxidative stress","49/267","458/18866",5.89968170460867e-29,7.36427768777777e-26,2.63777874108687e-26,"GCLC/CD38/VRK2/PTGS2/REST/HDAC6/SIRT1/MAPK1/HIF1A/MAPK3/MAPK8/FGF8/COL1A1/PPARGC1A/SOD2/PDGFRB/TPO/MTR/DUSP1/PTK2B/ATF4/APOE/CYP2E1/KDM6B/LDHA/IL6/IL10/TOR1A/TP53/SOD1/AKT1/NOS3/CTNNB1/FOS/BCL2/ATP2A2/PAWR/JUN/NQO1/ADIPOQ/PENK/PRKN/MAPT/LRRK2/HDAC2/TNF/GPX1/INS/HP",49]
["GO:1901215","negative regulation of neuron death","36/267","212/18866",1.81106510389514e-28,1.80852961274969e-25,6.47789391898494e-26,"GCLC/TNFRSF1B/GRN/ERBB3/GSK3B/REST/BAX/SIRT1/HIF1A/ADNP/FGF8/CCL2/PPARGC1A/SOD2/CREB1/PTK2B/PIK3CA/ATF4/APOE/KRAS/NGF/IL10/SOD1/AKT1/NTRK2/PRKCI/CDK5/CTNNB1/GDNF/MECP2/BCL2L1/BCL2/BDNF/JUN/PRKN/LRRK2",36]
["GO:0048732","gland development","47/267","443/18866",1.30167327528376e-27,1.08320911058197e-24,3.87989981527561e-25,"PAX6/TG/POU1F1/FGFR2/GLI2/FGFR1/BAX/ESR1/MAPK1/XBP1/TSPO/HIF1A/MAPK3/SFRP1/TGFB1/FGF8/VDR/SRF/VEGFA/PDGFRB/CREB1/PIK3CA/KRAS/IL6/IL10/BRCA2/SOD1/AKT1/SLC6A3/SRD5A1/DRD2/HESX1/SHH/CTNNB1/FADD/MAP2K1/AR/BCL2/PTEN/PRL/JUN/ERBB4/CSF1R/PTCH1/NF1/TNF/GPX1",47]
["GO:0097191","extrinsic apoptotic signaling pathway","36/267","230/18866",3.55446061016964e-27,2.53534597522529e-24,9.08124597996725e-25,"GCLC/BRCA1/IGF1/TNFRSF1B/ERBB3/TNFRSF1A/FGFR3/FGFR1/GSK3B/BAX/P2RX7/GATA1/SFRP1/TGFB1/IL2/IFNG/IL1A/IL1B/NGF/COL2A1/AKT1/PIK3R1/IL6R/ATF3/NOS3/RET/FADD/GDNF/AR/BCL2L1/BCL2/PTEN/DCC/NF1/TNF/GPX1",36]
["GO:0051402","neuron apoptotic process","36/267","245/18866",3.47277792422514e-26,2.01636617153887e-23,7.22233469055528e-24,"GCLC/GRN/NGFR/ERBB3/HDAC4/BAX/HIF1A/ADNP/FGF8/CCL2/PPARGC1A/SOD2/PTK2B/PIK3CA/ATF4/APOE/KRAS/NGF/IL10/TP53/SOD1/NTRK2/PRKCI/CDK5/CTNNB1/FADD/GDNF/MECP2/BCL2L1/BCL2/BDNF/JUN/NQO1/PRKN/NF1/TNF",36]
["GO:0050804","modulation of chemical synaptic transmission","46/267","454/18866",3.67313339085601e-26,2.01636617153887e-23,7.22233469055528e-24,"CD38/TAC1/PRKACA/PTGS2/GSK3B/MAPK1/ADNP/OXT/HTR2A/CCL2/SRF/CREB1/CNR1/PTK2B/IL1B/ATF4/APOE/KRAS/NGF/GLUL/TOR1A/PLK2/NTRK2/DRD2/SORCS3/S100B/SQSTM1/CDK5/GDNF/MECP2/PRKCE/PTEN/CALB2/SNCG/ATP2A2/BDNF/ADIPOQ/PRKN/MAPT/DCC/LRRK2/NF1/MTOR/AGER/TNF/INS",46]
["GO:0099177","regulation of trans-synaptic signaling","46/267","455/18866",4.03838608359477e-26,2.01636617153887e-23,7.22233469055528e-24,"CD38/TAC1/PRKACA/PTGS2/GSK3B/MAPK1/ADNP/OXT/HTR2A/CCL2/SRF/CREB1/CNR1/PTK2B/IL1B/ATF4/APOE/KRAS/NGF/GLUL/TOR1A/PLK2/NTRK2/DRD2/SORCS3/S100B/SQSTM1/CDK5/GDNF/MECP2/PRKCE/PTEN/CALB2/SNCG/ATP2A2/BDNF/ADIPOQ/PRKN/MAPT/DCC/LRRK2/NF1/MTOR/AGER/TNF/INS",46]
["GO:0043523","regulation of neuron apoptotic process","34/267","214/18866",6.30966854985311e-26,2.86401591540151e-23,1.02584946088042e-23,"GCLC/GRN/ERBB3/HDAC4/BAX/HIF1A/ADNP/FGF8/CCL2/PPARGC1A/SOD2/PTK2B/PIK3CA/ATF4/APOE/KRAS/NGF/IL10/TP53/SOD1/NTRK2/PRKCI/CDK5/CTNNB1/GDNF/MECP2/BCL2L1/BCL2/BDNF/JUN/NQO1/PRKN/NF1/TNF",34]
["GO:0007568","aging","39/267","319/18866",2.91462439251993e-25,1.21272663265434e-22,4.34381302008015e-23,"GCLC/TNFRSF1B/POU1F1/PTGS2/SIRT1/MAPK1/TSPO/HTR2A/MAPK3/PPARGC1A/SOD2/SRF/PDGFRB/CREB1/CNR1/KRAS/IL10/BRCA2/POLG/TP53/SOD1/AKT1/SLC6A3/PLK2/GNRH1/CDKN2A/MAP2K1/FOS/BCL2/PTEN/LEP/PAWR/JUN/NQO1/PENK/LRRK2/PAX5/MTOR/AGER",39]
["GO:0042063","gliogenesis","38/267","307/18866",7.95783546584384e-25,3.05642096007372e-22,1.09476619080718e-22,"PAX6/TNFRSF1B/GRN/ERBB3/MAPK1/TSPO/MAPK3/TGFB1/CCL2/IFNG/CREB1/PTK2B/IL1B/LIF/KRAS/IL6/SOD1/AKT1/NTRK2/S100B/PRKCI/SHH/CDK5/CTNNB1/MAP2K1/PTEN/PTPN11/F2/PENK/CSF1R/MED12/MAPT/HDAC2/NF1/DLL1/MTOR/AGER/TNF",38]
["GO:0031667","response to nutrient levels","45/267","473/18866",1.88497804843506e-24,6.72263956845446e-22,2.40795316112118e-22,"GCLC/PON1/ACSL4/PTGS2/COMT/SIRT1/MAPK1/XBP1/TSPO/OXT/MAPK3/SFRP1/MAPK8/COL1A1/PPARGC1A/VDR/OPRM1/SRF/POMC/CNR1/NPY/ATF4/APOE/LDHA/GLUL/TP53/SOD1/AKT1/SRD5A1/SST/ATF3/ALB/BCL2/PTEN/PRL/LEP/LPL/MTHFR/JUN/NQO1/ADIPOQ/PENK/CCK/LRRK2/MTOR",45]
["GO:0050890","cognition","37/267","302/18866",4.98321851809791e-24,1.65874733739086e-21,5.94139527175323e-22,"TAC1/PTGS2/COMT/MAPK1/EP300/HIF1A/ADNP/OXT/HTR2A/SRF/CREB1/CNR1/GRPR/APOE/PPP1R1B/KRAS/NGF/PLK2/NTRK2/DRD2/SORCS3/S100B/CDK5/MECP2/FOS/CHD7/PTEN/BDNF/JUN/PRKN/MAPT/CCK/NF1/MTOR/AGER/TNF/INS",37]
["GO:0018108","peptidyl-tyrosine phosphorylation","40/267","374/18866",1.12024320389155e-23,3.49585894814407e-21,1.25216658119194e-21,"IGF1/ERBB3/FGFR2/TNFRSF1A/FGFR3/FGFR1/ADNP/GATA1/HTR2A/MAPK3/SFRP1/TGFB1/FGF8/IL2/IFNG/VEGFA/PDGFRB/PTK2B/MAP2K2/LIF/IL6/TP53/NTRK2/IL18/ACE/IL6R/RET/MAP2K1/ALK/PRKCE/LEP/BDNF/ERBB4/PTPN11/ADIPOQ/CSF1R/CCK/HDAC2/MTOR/TNF",40]
["GO:0018212","peptidyl-tyrosine modification","40/267","377/18866",1.51429238388339e-23,4.44756580748809e-21,1.59305434069218e-21,"IGF1/ERBB3/FGFR2/TNFRSF1A/FGFR3/FGFR1/ADNP/GATA1/HTR2A/MAPK3/SFRP1/TGFB1/FGF8/IL2/IFNG/VEGFA/PDGFRB/PTK2B/MAP2K2/LIF/IL6/TP53/NTRK2/IL18/ACE/IL6R/RET/MAP2K1/ALK/PRKCE/LEP/BDNF/ERBB4/PTPN11/ADIPOQ/CSF1R/CCK/HDAC2/MTOR/TNF",40]
["GO:0007611","learning or memory","34/267","260/18866",4.51183041530053e-23,1.25153162575531e-20,4.48280694479275e-21,"TAC1/PTGS2/COMT/MAPK1/EP300/HIF1A/ADNP/OXT/HTR2A/SRF/CREB1/CNR1/GRPR/APOE/PPP1R1B/KRAS/NGF/PLK2/NTRK2/DRD2/SORCS3/S100B/CDK5/MECP2/FOS/PTEN/BDNF/JUN/PRKN/MAPT/CCK/NF1/MTOR/AGER",34]
["GO:0072593","reactive oxygen species metabolic process","35/267","288/18866",1.19794241549981e-22,3.14806656873186e-20,1.12759233458957e-20,"NOS2/BRCA1/HDAC4/PTGS2/P2RX7/HDAC6/TSPO/HIF1A/TGFB1/IFNG/SOD2/PDGFRB/TPO/PTK2B/IL1B/CRP/RAC1/IL10/CYP1A2/TP53/SOD1/AKT1/NOS3/BCL2/LEP/F2/NQO1/PRKN/MAPT/LRRK2/MTOR/TNF/GPX1/INS/HP",35]
["GO:0048638","regulation of developmental growth","38/267","353/18866",1.27103960624896e-22,3.17315037700052e-20,1.13657699527209e-20,"IGF1/POU1F1/FGFR2/FGFR3/FGFR1/GSK3B/MAPK1/ADNP/SFRP1/FGF8/SRF/VEGFA/CREB1/PIK3CA/APOE/NGF/DUSP6/FTO/SOD1/AKT1/SLC6A3/DRD2/CDK5/AR/CHD7/BCL2/PTEN/PRL/LEP/BDNF/ERBB4/PRKN/PTCH1/MAPT/DCC/DLL1/MTOR/L1CAM",38]
["GO:0050731","positive regulation of peptidyl-tyrosine phosphorylation","30/267","195/18866",1.49550415743922e-22,3.55573917052096e-20,1.2736148187916e-20,"IGF1/ERBB3/TNFRSF1A/FGFR3/ADNP/GATA1/HTR2A/TGFB1/FGF8/IL2/IFNG/VEGFA/PTK2B/LIF/IL6/TP53/NTRK2/IL18/ACE/IL6R/LEP/BDNF/ERBB4/PTPN11/ADIPOQ/CSF1R/CCK/HDAC2/MTOR/TNF",30]
["GO:0000302","response to reactive oxygen species","32/267","235/18866",2.5904704282755e-22,5.87919038562707e-20,2.10584175006702e-20,"HDAC6/SIRT1/MAPK1/MAPK3/MAPK8/COL1A1/PPARGC1A/SOD2/PDGFRB/MTR/DUSP1/PTK2B/APOE/CYP2E1/KDM6B/LDHA/IL6/IL10/SOD1/AKT1/NOS3/FOS/BCL2/PAWR/JUN/NQO1/MAPT/LRRK2/HDAC2/TNF/GPX1/HP",32]
["GO:0050769","positive regulation of neurogenesis","43/267","485/18866",3.60606738929183e-22,7.82830194553656e-20,2.80398558096422e-20,"PAX6/TNFRSF1B/GRN/NGFR/GLI2/FGFR1/REST/TSPO/EP300/HIF1A/ADNP/TGFB1/IL2/IFNG/OPRM1/SRF/VEGFA/CNR1/PTK2B/IL1B/LIF/APOE/NGF/IL6/NTRK2/DRD2/DVL3/PRKCI/SHH/RET/CTNNB1/MAP2K1/ALK/BCL2/PTEN/BDNF/PRKN/MAPT/HDAC2/TCF4/MTOR/L1CAM/TNF",43]
["GO:0050730","regulation of peptidyl-tyrosine phosphorylation","33/267","263/18866",7.68589335460383e-22,1.59898606331404e-19,5.72733895152277e-20,"IGF1/ERBB3/TNFRSF1A/FGFR3/ADNP/GATA1/HTR2A/SFRP1/TGFB1/FGF8/IL2/IFNG/VEGFA/PDGFRB/PTK2B/LIF/IL6/TP53/NTRK2/IL18/ACE/IL6R/PRKCE/LEP/BDNF/ERBB4/PTPN11/ADIPOQ/CSF1R/CCK/HDAC2/MTOR/TNF",33]
["GO:0034599","cellular response to oxidative stress","35/267","310/18866",1.41253421442364e-21,2.8211133330469e-19,1.01048237065506e-19,"VRK2/REST/HDAC6/SIRT1/MAPK1/HIF1A/MAPK3/MAPK8/PPARGC1A/SOD2/PDGFRB/MTR/ATF4/KDM6B/IL6/IL10/TP53/SOD1/AKT1/NOS3/CTNNB1/FOS/BCL2/ATP2A2/PAWR/JUN/NQO1/PENK/PRKN/MAPT/LRRK2/HDAC2/TNF/GPX1/INS",35]
["GO:0010001","glial cell differentiation","31/267","230/18866",1.65539099736981e-21,3.17898740379519e-19,1.13866773462806e-19,"PAX6/TNFRSF1B/GRN/ERBB3/MAPK1/MAPK3/TGFB1/IFNG/IL1B/LIF/KRAS/IL6/SOD1/AKT1/NTRK2/S100B/SHH/CDK5/CTNNB1/MAP2K1/PTEN/PTPN11/F2/MED12/MAPT/HDAC2/NF1/DLL1/MTOR/AGER/TNF",31]
["GO:0062197","cellular response to chemical stress","37/267","360/18866",2.40999829701541e-21,4.45671166555479e-19,1.59633025599578e-19,"VRK2/PTGS2/REST/HDAC6/SIRT1/MAPK1/TSPO/HIF1A/MAPK3/MAPK8/PPARGC1A/SOD2/PDGFRB/MTR/ATF4/KDM6B/IL6/IL10/TP53/SOD1/AKT1/NOS3/CTNNB1/FOS/BCL2/ATP2A2/PAWR/JUN/NQO1/PENK/PRKN/MAPT/LRRK2/HDAC2/TNF/GPX1/INS",37]
["GO:0043524","negative regulation of neuron apoptotic process","26/267","149/18866",4.07440960504635e-21,7.26554541357015e-19,2.60241425525329e-19,"GCLC/GRN/ERBB3/BAX/HIF1A/ADNP/FGF8/CCL2/PPARGC1A/SOD2/PTK2B/PIK3CA/APOE/KRAS/NGF/IL10/SOD1/NTRK2/PRKCI/GDNF/MECP2/BCL2L1/BCL2/BDNF/JUN/PRKN",26]
["GO:0071496","cellular response to external stimulus","35/267","326/18866",7.48800319963013e-21,1.25081674039215e-18,4.48024632786168e-19,"GCLC/TNFRSF1A/HDAC4/PTGS2/P2RX7/COMT/SIRT1/MAPK1/XBP1/ADNP/MAPK3/SFRP1/MAPK8/COL1A1/VDR/SRF/IL1B/ATF4/GLUL/RAC1/TP53/AKT1/SRD5A1/ATF3/ALB/FADD/FOS/BCL2/LEP/LPL/JUN/PTPN11/PENK/LRRK2/MTOR",35]
["GO:0070482","response to oxygen levels","38/267","396/18866",7.5154220331994e-21,1.25081674039215e-18,4.48024632786168e-19,"CD38/CREBBP/NOS2/PTGS2/REST/SIRT1/EP300/HIF1A/SFRP1/COL1A1/PPARGC1A/SRF/VEGFA/PDGFRB/CREB1/PTK2B/ATF4/LDHA/POLG/TP53/AKT1/DRD2/EDNRA/S100B/MECP2/PRKCE/BCL2/PTEN/LEP/MTHFR/ADIPOQ/PENK/HDAC2/NF1/DPP4/MTOR/AGER/MALAT1",38]
["GO:0048568","embryonic organ development","40/267","451/18866",1.16033590911588e-20,1.8688894174889e-18,6.69409409028142e-19,"PAX6/COL11A1/FGFR2/GLI2/DLG1/FGFR1/GNAS/MAPK1/HIF1A/GATA1/MAPK3/TGFB1/FGF8/SRF/VEGFA/PDGFRB/TPO/KMT2A/ATF4/LIF/IL10/COL2A1/TP53/SOD1/AKT1/KDM6A/HESX1/SHH/FBN1/CTNNB1/GDNF/MAP2K1/CXCL8/CHD7/FZD2/MED12/PTCH1/PAX5/DLL1/TNF",40]
["GO:0035270","endocrine system development","24/267","125/18866",1.33059689501332e-20,2.07614696775047e-18,7.43646093627511e-19,"PAX6/TG/POU1F1/GLI2/GSK3B/MAPK1/TSPO/MAPK3/FGF8/SRF/PDGFRB/CREB1/MEN1/IL6/AKT1/SLC6A3/SRD5A1/DRD2/IL6R/HESX1/SHH/MAP2K1/NF1/DLL1",24]
["GO:0032496","response to lipopolysaccharide","35/267","334/18866",1.66308790594255e-20,2.51630239829428e-18,9.01303461625641e-19,"TAC1/NOS2/TNFRSF1B/FGFR2/PTGS2/APOB/P2RX7/COMT/MAPK1/XBP1/TSPO/MAPK3/TGFB1/MAPK8/CCL2/PPARGC1A/OPRM1/IL1A/CNR1/IL1B/IDO1/IL6/IL10/CYP1A2/AKT1/GNRH1/IL18/NOS3/CXCL8/FOS/PRKCE/ATP2A2/PENK/HDAC2/TNF",35]
["GO:0060537","muscle tissue development","38/267","409/18866",2.32694736577556e-20,3.41719064626981e-18,1.22398872274076e-18,"IGF1/HDAC9/COL11A1/ERBB3/FGFR2/HDAC4/DLG1/FGFR1/MAPK1/EP300/TGFB1/FGF8/PRKAR1A/PPARGC1A/SRF/VEGFA/PDGFRB/CREB1/KDM6B/FLNB/S100B/ATF3/PDLIM5/SHH/CDK5/CTNNB1/FOS/CHD7/BCL2/PTEN/ERBB4/NEB/PTCH1/PAX5/NF1/DLL1/MTOR/GPX1",38]
["GO:0001503","ossification","38/267","412/18866",3.00193355728183e-20,4.28247264328805e-18,1.53392033498401e-18,"TAC1/IGF1/COL11A1/FGFR2/HDAC4/FGFR3/PRKACA/PTGS2/GLI2/REST/GNAS/P2RX7/MAPK1/HIF1A/OXT/GATA1/MAPK3/SFRP1/TGFB1/COL1A1/PTK2B/ATF4/MEN1/IL6/COL2A1/AKT1/IL6R/SHH/INPPL1/CTNNB1/BCL2/LEP/PTPN11/PENK/PTCH1/NF1/TNF/TWIST2",38]
["GO:2001233","regulation of apoptotic signaling pathway","38/267","413/18866",3.26631259378993e-20,4.53019410577586e-18,1.62265061311377e-18,"GCLC/BRCA1/IGF1/NGFR/PTGS2/FGFR1/GSK3B/BAX/SIRT1/XBP1/HIF1A/GATA1/SFRP1/MAPK8/SOD2/IL1A/IL1B/COL2A1/TP53/SOD1/AKT1/ATF3/NOS3/RET/CTNNB1/FADD/GDNF/AR/BCL2L1/BCL2/PTEN/BDNF/PRKN/LRRK2/NF1/TNF/GPX1/INS",38]
["GO:0051098","regulation of binding","36/267","367/18866",4.16221360140879e-20,5.61673851671191e-18,2.01183525143486e-18,"PON1/PAX6/IGF1/HDAC4/PRKACA/GSK3B/BAX/CYP2D6/EP300/ADNP/GATA1/MAPK3/TGFB1/MAPK8/IFNG/STMN1/LIF/APOE/PER2/PRMT7/MEN1/NGF/IL10/AKT1/PLK2/ACE/CDK5/CTNNB1/ATP2A2/BDNF/JUN/ADIPOQ/PRKN/LRRK2/HDAC2/AGER",36]
["GO:0043491","protein kinase B signaling","32/267","278/18866",4.72026705761313e-20,6.20218247859535e-18,2.22153288944175e-18,"IGF1/ERBB3/FGFR2/FGFR3/DLG1/FGFR1/ESR1/SIRT1/TSC2/TGFB1/FGF8/CCL2/PDGFRB/PIK3CA/IL1B/RAC1/AKT1/PIK3R1/NTRK2/DRD2/IL18/FGF17/RET/PTEN/LEP/ERBB4/PTPN11/MTOR/TNF/GPX1/INS/MC1R",32]
["GO:0050673","epithelial cell proliferation","39/267","453/18866",1.05523591354412e-19,1.35097254264764e-17,4.83899005968006e-18,"PAX6/IGF1/GRN/NGFR/FGFR2/DLG1/FGFR1/BAX/ESR1/SIRT1/MAPK1/XBP1/HIF1A/SFRP1/TGFB1/CCL2/VDR/VEGFA/APOE/MEN1/GLUL/IL6/IL10/BRCA2/CDH13/AKT1/SHH/CTNNB1/MAP2K1/AR/PTEN/PRL/LEP/JUN/PTCH1/NF1/MTOR/TNF/GPX1",39]
["GO:0033002","muscle cell proliferation","30/267","244/18866",1.11456271509533e-19,1.39125290911774e-17,4.98326856038673e-18,"IGF1/FGFR2/HDAC4/PTGS2/NOTCH3/FGFR1/COMT/MAPK1/PRKAR1A/PPARGC1A/IFNG/SOD2/PDGFRB/MFN2/DNMT1/IL6/IL10/CDH13/AKT1/IL18/IL6R/SHH/NOS3/CTNNB1/PTEN/JUN/ERBB4/ADIPOQ/MTOR/TNF",30]
["GO:0007409","axonogenesis","40/267","482/18866",1.2831506851187e-19,1.56262716360919e-17,5.59710658284128e-18,"PAX6/NGFR/FGFR2/GLI2/NOTCH3/GSK3B/HDAC6/MAPK1/ADNP/MAPK3/FGF8/SRF/VEGFA/STMN1/CREB1/PIK3CA/APOE/NGF/RAC1/PIK3R1/NTRK2/NCAM1/DRD2/S100B/SHH/CDK5/OTX2/RET/GDNF/MAP2K1/BCL2/PTEN/BDNF/PTPN11/CSF1R/PTCH1/MAPT/CCK/DCC/L1CAM",40]
["GO:0002237","response to molecule of bacterial origin","35/267","356/18866",1.33405909277805e-19,1.58488448057986e-17,5.67682910286018e-18,"TAC1/NOS2/TNFRSF1B/FGFR2/PTGS2/APOB/P2RX7/COMT/MAPK1/XBP1/TSPO/MAPK3/TGFB1/MAPK8/CCL2/PPARGC1A/OPRM1/IL1A/CNR1/IL1B/IDO1/IL6/IL10/CYP1A2/AKT1/GNRH1/IL18/NOS3/CXCL8/FOS/PRKCE/ATP2A2/PENK/HDAC2/TNF",35]
["GO:0018105","peptidyl-serine phosphorylation","33/267","310/18866",1.3649115294399e-19,1.58488448057986e-17,5.67682910286018e-18,"VRK2/PRKACA/PTGS2/GSK3B/BAX/HDAC6/MAPK1/MAPK3/TGFB1/MAPK8/IFNG/VEGFA/PIK3CA/MAP2K2/LIF/NGF/IL6/AKT1/PLK2/NTRK2/BRAF/PRKCI/CDK5/RET/PRKCE/BCL2/PTEN/BDNF/LRRK2/IFNA1/MTOR/DMD/TNF",33]
["GO:0045927","positive regulation of growth","31/267","274/18866",3.11791819574272e-19,3.53812853439623e-17,1.26730694128394e-17,"CD38/IGF1/POU1F1/FGFR2/FGFR1/MAPK1/ADNP/SFRP1/FGF8/IL2/SRF/VEGFA/CREB1/PTK2B/NGF/ADAM10/AKT1/SLC6A3/DRD2/CHD7/BCL2/LEP/BDNF/ERBB4/F2/PRKN/MAPT/DLL1/MTOR/L1CAM/INS",31]
["GO:0062012","regulation of small molecule metabolic process","38/267","456/18866",9.91172863061245e-19,1.08164721919391e-16,3.87430534413539e-17,"NOS2/BRCA1/IGF1/POU1F1/HDAC4/PTGS2/GSK3B/REST/APOB/P2RX7/COMT/SIRT1/EP300/HIF1A/HTR2A/TGFB1/PPARGC1A/VDR/IFNG/GNB3/POMC/CNR1/PTK2B/IL1B/APOE/TP53/SOD1/AKT1/NOS3/VCP/PRKCE/LEP/NQO1/ADIPOQ/PRKN/MTOR/TNF/INS",38]
["GO:0042110","T cell activation","39/267","483/18866",9.96510556437413e-19,1.08164721919391e-16,3.87430534413539e-17,"IGF1/TNFRSF1B/GLI2/DLG1/BAX/P2RX7/XBP1/CCL2/PRKAR1A/IL2/IFNG/SRF/IL1A/PIK3CA/IL1B/IDO1/RAC1/IL6/IL10/TP53/SOD1/AKT1/PIK3R1/GNRH1/IL18/SHH/CTNNB1/FADD/CHD7/BCL2/LEP/PAWR/PTPN11/HLA-DRB1/DPP4/IFNA1/MTOR/AGER/INS",39]
["GO:0018209","peptidyl-serine modification","33/267","333/18866",1.23893700113982e-18,1.31617286099812e-16,4.71434258664403e-17,"VRK2/PRKACA/PTGS2/GSK3B/BAX/HDAC6/MAPK1/MAPK3/TGFB1/MAPK8/IFNG/VEGFA/PIK3CA/MAP2K2/LIF/NGF/IL6/AKT1/PLK2/NTRK2/BRAF/PRKCI/CDK5/RET/PRKCE/BCL2/PTEN/BDNF/LRRK2/IFNA1/MTOR/DMD/TNF",33]
["GO:0046883","regulation of hormone secretion","30/267","267/18866",1.47797081786826e-18,1.53739756117004e-16,5.50673776218897e-17,"CD38/TAC1/NOS2/ACSL4/FGFR1/REST/GNAS/HIF1A/SFRP1/IFNG/POMC/CREB1/CNR1/IL1B/LIF/PER2/GLUL/RAC1/IL6/DRD2/PRKCE/CHD7/LEP/PTPN11/ADIPOQ/PRKN/HLA-DRB1/DPP4/TNF/INS",30]
["GO:0007613","memory","22/267","121/18866",1.93209101387243e-18,1.96876131270715e-16,7.05182090777498e-17,"TAC1/PTGS2/COMT/ADNP/OXT/HTR2A/SRF/CREB1/CNR1/APOE/PPP1R1B/NGF/PLK2/DRD2/SORCS3/S100B/MECP2/PTEN/BDNF/MAPT/CCK/MTOR",22]
["GO:0014706","striated muscle tissue development","35/267","389/18866",2.30781334123614e-18,2.30458240255841e-16,8.25468393002148e-17,"IGF1/HDAC9/COL11A1/ERBB3/FGFR2/HDAC4/FGFR1/MAPK1/EP300/TGFB1/FGF8/PRKAR1A/SRF/VEGFA/PDGFRB/CREB1/KDM6B/FLNB/S100B/ATF3/PDLIM5/SHH/CDK5/CTNNB1/FOS/CHD7/BCL2/PTEN/ERBB4/NEB/PAX5/NF1/DLL1/MTOR/GPX1",35]
["GO:0050806","positive regulation of synaptic transmission","25/267","172/18866",2.39972571365997e-18,2.34937852711848e-16,8.41513722911929e-17,"TAC1/PTGS2/GSK3B/MAPK1/OXT/CCL2/CREB1/CNR1/PTK2B/APOE/GLUL/PLK2/NTRK2/DRD2/S100B/SQSTM1/CDK5/MECP2/PRKCE/PTEN/CALB2/NF1/AGER/TNF/INS",25]
["GO:0048608","reproductive structure development","37/267","443/18866",2.74246796600262e-18,2.60981457426078e-16,9.3479818307084e-17,"FGFR2/PTGS2/GLI2/DLG1/ATRX/BAX/ESR1/SIRT1/MAPK1/HIF1A/GATA1/MAPK3/SFRP1/FGF8/VDR/VEGFA/PDGFRB/LIF/MEN1/IL10/BRCA2/SOD1/AKT1/SRD5A1/GNRH1/SHH/NOS3/CTNNB1/MAP2K1/AR/CHD7/BCL2L1/BCL2/PTEN/LEP/PTPN11/PTCH1",37]
["GO:0048660","regulation of smooth muscle cell proliferation","25/267","173/18866",2.77028184329705e-18,2.60981457426078e-16,9.3479818307084e-17,"IGF1/FGFR2/HDAC4/PTGS2/NOTCH3/COMT/PPARGC1A/IFNG/SOD2/PDGFRB/MFN2/DNMT1/IL6/IL10/CDH13/AKT1/IL18/IL6R/NOS3/CTNNB1/PTEN/JUN/ADIPOQ/MTOR/TNF",25]
["GO:0051896","regulation of protein kinase B signaling","29/267","253/18866",3.28924153914292e-18,3.04133018610011e-16,1.08936089181361e-16,"ERBB3/FGFR2/FGFR3/DLG1/FGFR1/ESR1/SIRT1/TSC2/TGFB1/FGF8/PDGFRB/PIK3CA/RAC1/AKT1/PIK3R1/NTRK2/DRD2/IL18/FGF17/RET/PTEN/LEP/ERBB4/PTPN11/MTOR/TNF/GPX1/INS/MC1R",29]
["GO:2001234","negative regulation of apoptotic signaling pathway","28/267","233/18866",3.6417139716117e-18,3.23335668401403e-16,1.15814203171595e-16,"GCLC/BRCA1/IGF1/PTGS2/GSK3B/BAX/SIRT1/XBP1/HIF1A/GATA1/SOD2/IL1A/IL1B/COL2A1/AKT1/NOS3/CTNNB1/FADD/GDNF/AR/BCL2L1/BCL2/BDNF/PRKN/LRRK2/TNF/GPX1/INS",28]
["GO:0048659","smooth muscle cell proliferation","25/267","175/18866",3.68119789052048e-18,3.23335668401403e-16,1.15814203171595e-16,"IGF1/FGFR2/HDAC4/PTGS2/NOTCH3/COMT/PPARGC1A/IFNG/SOD2/PDGFRB/MFN2/DNMT1/IL6/IL10/CDH13/AKT1/IL18/IL6R/NOS3/CTNNB1/PTEN/JUN/ADIPOQ/MTOR/TNF",25]
["GO:0061458","reproductive system development","37/267","447/18866",3.69500874754391e-18,3.23335668401403e-16,1.15814203171595e-16,"FGFR2/PTGS2/GLI2/DLG1/ATRX/BAX/ESR1/SIRT1/MAPK1/HIF1A/GATA1/MAPK3/SFRP1/FGF8/VDR/VEGFA/PDGFRB/LIF/MEN1/IL10/BRCA2/SOD1/AKT1/SRD5A1/GNRH1/SHH/NOS3/CTNNB1/MAP2K1/AR/CHD7/BCL2L1/BCL2/PTEN/LEP/PTPN11/PTCH1",37]
["GO:0050678","regulation of epithelial cell proliferation","35/267","395/18866",3.7559520863772e-18,3.23335668401403e-16,1.15814203171595e-16,"PAX6/IGF1/GRN/NGFR/FGFR2/DLG1/FGFR1/BAX/SIRT1/XBP1/HIF1A/SFRP1/TGFB1/CCL2/VDR/VEGFA/APOE/MEN1/GLUL/IL10/BRCA2/CDH13/AKT1/SHH/CTNNB1/AR/PTEN/PRL/LEP/JUN/PTCH1/NF1/MTOR/TNF/GPX1",35]
["GO:0036293","response to decreased oxygen levels","34/267","371/18866",4.14024033720693e-18,3.50376610231766e-16,1.25499881051108e-16,"CD38/CREBBP/NOS2/PTGS2/REST/SIRT1/EP300/HIF1A/SFRP1/PPARGC1A/SRF/VEGFA/CREB1/PTK2B/ATF4/LDHA/TP53/AKT1/DRD2/EDNRA/S100B/MECP2/PRKCE/BCL2/PTEN/LEP/MTHFR/ADIPOQ/PENK/NF1/DPP4/MTOR/AGER/MALAT1",34]
["GO:0048708","astrocyte differentiation","19/267","83/18866",4.3922325772306e-18,3.65506954301873e-16,1.30919353486224e-16,"PAX6/GRN/MAPK1/MAPK3/IFNG/IL1B/LIF/KRAS/IL6/S100B/SHH/MAP2K1/PTPN11/F2/MAPT/NF1/DLL1/AGER/TNF",19]
["GO:0070371","ERK1 and ERK2 cascade","32/267","325/18866",5.17924018483358e-18,4.23933544965149e-16,1.51846921035932e-16,"IGF1/FGFR2/FGFR3/DLG1/MAPK1/HTR2A/MAPK3/TGFB1/FGF8/CCL2/OPRM1/PDGFRB/DUSP1/PTK2B/IL1B/MAP2K2/LIF/APOE/DUSP6/DRD2/BRAF/ATF3/MAP2K1/PTEN/JUN/ERBB4/PTPN11/ADIPOQ/CSF1R/HLA-DRB1/AGER/TNF",32]
["GO:2000377","regulation of reactive oxygen species metabolic process","26/267","200/18866",8.44927387006745e-18,6.80439103762045e-16,2.43723536591589e-16,"BRCA1/HDAC4/PTGS2/HDAC6/TSPO/HIF1A/TGFB1/IFNG/PDGFRB/PTK2B/IL1B/CRP/RAC1/IL10/TP53/SOD1/AKT1/BCL2/LEP/F2/PRKN/MAPT/MTOR/TNF/INS/HP",26]
["GO:0060562","epithelial tube morphogenesis","32/267","331/18866",8.89708775807412e-18,7.05129510731176e-16,2.5256728656588e-16,"FGFR2/PRKACA/GLI2/DLG1/ESR1/HIF1A/TSC2/SFRP1/TGFB1/FGF8/VDR/TIMELESS/SRF/VEGFA/KRAS/KDM6A/EDNRA/DVL3/HESX1/SHH/RET/CTNNB1/GDNF/AR/BCL2/MTHFR/FZD2/CSF1R/MED12/PTCH1/DLL1/TNF",32]
["GO:0001666","response to hypoxia","33/267","359/18866",1.21623835831314e-17,9.48855956727737e-16,3.39866607035202e-16,"CD38/CREBBP/NOS2/PTGS2/REST/SIRT1/EP300/HIF1A/SFRP1/PPARGC1A/SRF/VEGFA/CREB1/PTK2B/LDHA/TP53/AKT1/DRD2/EDNRA/S100B/MECP2/PRKCE/BCL2/PTEN/LEP/MTHFR/ADIPOQ/PENK/NF1/DPP4/MTOR/AGER/MALAT1",33]
["GO:0038034","signal transduction in absence of ligand","18/267","75/18866",1.35714218449585e-17,1.01137476525191e-15,3.62259948383104e-16,"ERBB3/FGFR1/GSK3B/BAX/GATA1/IL2/IL1A/IL1B/COL2A1/AKT1/RET/FADD/GDNF/BCL2L1/BCL2/DCC/NF1/TNF",18]
["GO:0050805","negative regulation of synaptic transmission","18/267","75/18866",1.35714218449585e-17,1.01137476525191e-15,3.62259948383104e-16,"CD38/PTGS2/ADNP/HTR2A/SRF/PTK2B/IL1B/PLK2/DRD2/SORCS3/PTEN/BDNF/ADIPOQ/PRKN/MAPT/LRRK2/NF1/AGER",18]
["GO:0097192","extrinsic apoptotic signaling pathway in absence of ligand","18/267","75/18866",1.35714218449585e-17,1.01137476525191e-15,3.62259948383104e-16,"ERBB3/FGFR1/GSK3B/BAX/GATA1/IL2/IL1A/IL1B/COL2A1/AKT1/RET/FADD/GDNF/BCL2L1/BCL2/DCC/NF1/TNF",18]
["GO:0070661","leukocyte proliferation","31/267","313/18866",1.4972664323459e-17,1.09938989657398e-15,3.93785707206762e-16,"CD38/TAC1/IGF1/TNFRSF1B/DLG1/BAX/P2RX7/MAPK1/MAPK3/PRKAR1A/IL2/IL1A/IL1B/IDO1/CRP/IL6/IL10/TP53/GNRH1/IL18/ACE/SHH/CTNNB1/FADD/BCL2/LEP/PAWR/CSF1R/HLA-DRB1/IFNA1/AGER",31]
["GO:0030900","forebrain development","34/267","391/18866",2.0965387599834e-17,1.51710406211552e-15,5.43404935653973e-16,"PAX6/POU1F1/FGFR2/GLI2/NOTCH3/FGFR1/GSK3B/ATRX/BAX/HIF1A/FGF8/PPARGC1A/SRF/CREB1/NPY/KDM6B/KRAS/SLC6A3/SRD5A1/NTRK2/DRD2/HESX1/SHH/CDK5/OTX2/CTNNB1/ALK/CHD7/PTEN/ERBB4/CSF1R/LRRK2/PAX5/NF1",34]
["GO:0048167","regulation of synaptic plasticity","25/267","191/18866",3.14532473696162e-17,2.2435152016642e-15,8.03594996706435e-16,"CD38/PTGS2/GSK3B/MAPK1/SRF/CREB1/PTK2B/ATF4/APOE/KRAS/PLK2/NTRK2/DRD2/SORCS3/S100B/SQSTM1/CDK5/MECP2/PTEN/CALB2/BDNF/MAPT/NF1/AGER/INS",25]
["GO:0030278","regulation of ossification","26/267","212/18866",3.65917109151566e-17,2.55540757793899e-15,9.15310376615335e-16,"TAC1/IGF1/FGFR2/HDAC4/PRKACA/REST/GNAS/P2RX7/MAPK1/HIF1A/OXT/GATA1/MAPK3/SFRP1/TGFB1/PTK2B/ATF4/MEN1/IL6/IL6R/CTNNB1/BCL2/PTPN11/PTCH1/TNF/TWIST2",26]
["GO:0009914","hormone transport","31/267","323/18866",3.68494583640311e-17,2.55540757793899e-15,9.15310376615335e-16,"CD38/TAC1/NOS2/ACSL4/FGFR1/REST/GNAS/HIF1A/SFRP1/IFNG/POMC/CREB1/TTR/CNR1/IL1B/LIF/PER2/GLUL/RAC1/IL6/DRD2/PRKCE/CHD7/LEP/PTPN11/ADIPOQ/PRKN/HLA-DRB1/DPP4/TNF/INS",31]
["GO:0009266","response to temperature stimulus","27/267","233/18866",3.81089087971092e-17,2.60654495375296e-15,9.3362705185708e-16,"GCLC/CREBBP/IGF1/NGFR/PRKACA/PTGS2/GSK3B/SIRT1/MAPK1/EP300/HTR2A/MAPK3/BAG1/PPARGC1A/IL1A/SOD1/AKT1/SST/NOS3/VCP/FOS/ATP2A2/LPL/MAPT/HDAC2/NF1/MTOR",27]
["GO:0050708","regulation of protein secretion","32/267","352/18866",5.40926292018216e-17,3.64979050817155e-15,1.3073026602261e-15,"CD38/NOS2/IGF1/HDAC9/ACSL4/REST/P2RX7/XBP1/HIF1A/SFRP1/TGFB1/IL2/IFNG/OPRM1/IL1A/CNR1/IL1B/APOE/PER2/GLUL/RAC1/IL6/IL10/DRD2/PRKCE/LEP/PTPN11/PRKN/HLA-DRB1/DPP4/TNF/INS",32]
["GO:0007565","female pregnancy","25/267","196/18866",5.89022474985855e-17,3.92131895680583e-15,1.40456025965048e-15,"CD38/ACSL4/PTGS2/ESR1/COMT/MAPK1/OXT/MAPK3/VDR/VEGFA/CNR1/IL1B/LIF/IDO1/KRAS/MEN1/SOD1/AKT1/GNRH1/AR/FOS/BCL2/PRL/LEP/MTOR",25]
["GO:0048511","rhythmic process","30/267","305/18866",6.22238822409183e-17,4.0879453161698e-15,1.4642434338964e-15,"CREBBP/NOS2/NGFR/GSK3B/ESR1/SIRT1/EP300/ADNP/MAPK8/PPARGC1A/TIMELESS/OPRM1/KMT2A/CREB1/ATF4/PER2/TP53/SRD5A1/GNRH1/NTRK2/DRD2/NOS3/CDK5/PTEN/LEP/BDNF/JUN/ADIPOQ/HDAC2/MTOR",30]
["GO:0048771","tissue remodeling","24/267","178/18866",6.92904192930661e-17,4.49307874714648e-15,1.60935642349855e-15,"CD38/BAX/P2RX7/HIF1A/SFRP1/TGFB1/FGF8/IL2/VDR/IL1A/PTK2B/LIF/RAC1/IL6/TP53/IL18/ACE/NOS3/CTNNB1/CHD7/LEP/CSF1R/NF1/AGER",24]
["GO:0007517","muscle organ development","34/267","407/18866",7.1513234896026e-17,4.56947970120566e-15,1.63672215045241e-15,"IGF1/HDAC9/COL11A1/ERBB3/FGFR2/HDAC4/FGFR1/SIRT1/MAPK1/XBP1/EP300/TGFB1/FGF8/CREB1/LIF/FLNB/S100B/ATF3/SHH/CDK5/CTNNB1/FOS/CHD7/BCL2/PTEN/ERBB4/FZD2/NEB/PAX5/NF1/DLL1/MTOR/DMD/GPX1",34]
["GO:0002791","regulation of peptide secretion","33/267","381/18866",7.2298997876076e-17,4.56947970120566e-15,1.63672215045241e-15,"CD38/NOS2/IGF1/HDAC9/ACSL4/REST/P2RX7/XBP1/HIF1A/SFRP1/TGFB1/IL2/IFNG/OPRM1/IL1A/CNR1/IL1B/APOE/PER2/GLUL/RAC1/IL6/IL10/DRD2/PRKCE/CHD7/LEP/PTPN11/PRKN/HLA-DRB1/DPP4/TNF/INS",33]
["GO:2001236","regulation of extrinsic apoptotic signaling pathway","23/267","162/18866",9.78124438012291e-17,6.10471914874421e-15,2.18662292129327e-15,"GCLC/BRCA1/IGF1/FGFR1/GSK3B/GATA1/SFRP1/IL1A/IL1B/COL2A1/AKT1/ATF3/NOS3/RET/FADD/GDNF/AR/BCL2L1/BCL2/PTEN/NF1/TNF/GPX1",23]
["GO:1903532","positive regulation of secretion by cell","30/267","313/18866",1.27408972213157e-16,7.85374071926285e-15,2.81309738518718e-15,"CD38/TAC1/IGF1/ACSL4/FGFR1/P2RX7/XBP1/HIF1A/OXT/TGFB1/IL2/IFNG/IL1A/CREB1/CNR1/IL1B/GLUL/RAC1/IL6/IL10/DRD2/CDK5/GDNF/PRKCE/LEP/PTPN11/CCK/HLA-DRB1/TNF/INS",30]
["GO:0042593","glucose homeostasis","27/267","245/18866",1.37927067707739e-16,8.36985172488387e-15,2.99796095176989e-15,"GCLC/PAX6/NGFR/PRKACA/SIRT1/SMARCB1/XBP1/HIF1A/PPARGC1A/SRF/POMC/CNR1/PIK3CA/MEN1/RAC1/IL6/POLG/AKT1/PIK3R1/PRKCE/LEP/PTPN11/ADIPOQ/PTCH1/HLA-DRB1/AGER/INS",27]
["GO:0046879","hormone secretion","30/267","314/18866",1.39134326690439e-16,8.36985172488387e-15,2.99796095176989e-15,"CD38/TAC1/NOS2/ACSL4/FGFR1/REST/GNAS/HIF1A/SFRP1/IFNG/POMC/CREB1/CNR1/IL1B/LIF/PER2/GLUL/RAC1/IL6/DRD2/PRKCE/CHD7/LEP/PTPN11/ADIPOQ/PRKN/HLA-DRB1/DPP4/TNF/INS",30]
["GO:0033500","carbohydrate homeostasis","27/267","246/18866",1.5301446940173e-16,9.09525292527188e-15,3.25778926708696e-15,"GCLC/PAX6/NGFR/PRKACA/SIRT1/SMARCB1/XBP1/HIF1A/PPARGC1A/SRF/POMC/CNR1/PIK3CA/MEN1/RAC1/IL6/POLG/AKT1/PIK3R1/PRKCE/LEP/PTPN11/ADIPOQ/PTCH1/HLA-DRB1/AGER/INS",27]
["GO:0051047","positive regulation of secretion","31/267","340/18866",1.58167185884019e-16,9.2909265778695e-15,3.32787676553497e-15,"CD38/TAC1/IGF1/ACSL4/FGFR1/P2RX7/XBP1/HIF1A/OXT/TGFB1/IL2/IFNG/IL1A/CREB1/CNR1/IL1B/GLUL/RAC1/IL6/IL10/DRD2/CDK5/GDNF/PRKCE/PRL/LEP/PTPN11/CCK/HLA-DRB1/TNF/INS",31]
["GO:0010038","response to metal ion","32/267","366/18866",1.67910635568418e-16,9.74857910922224e-15,3.49180134431754e-15,"GCLC/PTGS2/P2RX7/FUS/MAPK1/TSPO/HIF1A/MAPK3/MAPK8/PPARGC1A/IL1A/CREB1/DUSP1/PTK2B/ATF4/CYP1A2/SOD1/AKT1/SLC6A3/GNRH1/DRD2/BRAF/SHH/FOS/BCL2/PTEN/JUN/NQO1/PENK/PRKN/MAPT/LRRK2",32]
["GO:0044706","multi-multicellular organism process","26/267","226/18866",1.79635031167961e-16,1.02922859181216e-14,3.68654933219953e-15,"CD38/TAC1/ACSL4/PTGS2/ESR1/COMT/MAPK1/OXT/MAPK3/VDR/VEGFA/CNR1/IL1B/LIF/IDO1/KRAS/MEN1/SOD1/AKT1/GNRH1/AR/FOS/BCL2/PRL/LEP/MTOR",26]
["GO:0009314","response to radiation","35/267","447/18866",1.81398189624415e-16,1.02922859181216e-14,3.68654933219953e-15,"CREBBP/BRCA1/PTGS2/BAX/SIRT1/EP300/HIF1A/SFRP1/MAPK8/OPRM1/CREB1/DUSP1/ATF4/PPP1R1B/PER2/KRAS/MEN1/REV1/BRCA2/POLG/TP53/AKT1/PIK3R1/DRD2/CDK5/MECP2/FOS/BCL2L1/BCL2/PENK/CCK/NF1/MTOR/GPX1/MC1R",35]
["GO:0009416","response to light stimulus","30/267","319/18866",2.14999704133515e-16,1.20617249745915e-14,4.32033704698808e-15,"CREBBP/PTGS2/BAX/SIRT1/EP300/HIF1A/MAPK8/CREB1/DUSP1/ATF4/PPP1R1B/PER2/KRAS/MEN1/REV1/BRCA2/POLG/TP53/AKT1/PIK3R1/DRD2/CDK5/MECP2/FOS/BCL2/CCK/NF1/MTOR/GPX1/MC1R",30]
["GO:0048639","positive regulation of developmental growth","24/267","187/18866",2.19464276934968e-16,1.21753903859588e-14,4.36105036856737e-15,"IGF1/POU1F1/FGFR2/FGFR1/MAPK1/ADNP/FGF8/SRF/VEGFA/CREB1/NGF/AKT1/SLC6A3/DRD2/CHD7/BCL2/LEP/BDNF/ERBB4/PRKN/MAPT/DLL1/MTOR/L1CAM",24]
["GO:0009636","response to toxic substance","27/267","250/18866",2.30629037040447e-16,1.26541844169555e-14,4.53254752957454e-15,"PON1/PTGS2/BAX/MAPK1/MAPK3/SOD2/SRF/PDGFRB/TPO/ATF4/APOE/KDM6B/GSTM1/SOD1/SRD5A1/DRD2/ALB/NOS3/FOS/BCL2/NQO1/EHMT1/PENK/PRKN/TNF/GPX1/HP",27]
["GO:0051051","negative regulation of transport","36/267","483/18866",3.07933052575497e-16,1.67120622990159e-14,5.98602123942529e-15,"GCLC/TNFRSF1B/HDAC9/ERBB3/TNFRSF1A/PTGS2/REST/COMT/OXT/HTR2A/SFRP1/OPRM1/CNR1/PTK2B/IL1B/ATF4/LIF/APOE/RAC1/AKT1/DRD2/SHH/NOS3/CDK5/PRKCE/BCL2/PTEN/LEP/PTPN11/ADIPOQ/PRKN/LRRK2/NF1/MTOR/TNF/INS",36]
["GO:0051090","regulation of DNA-binding transcription factor activity","35/267","455/18866",3.13612161177803e-16,1.68372636640943e-14,6.03086657431904e-15,"ZIC2/HDAC4/ESR1/SIRT1/SMARCB1/MAPK1/EP300/MAPK3/MAPK8/PPARGC1A/SRF/VEGFA/IL1B/KRAS/MEN1/IL6/IL10/ESR2/AKT1/CDKN2A/IL18/PRKCI/SHH/CTNNB1/AR/FOS/ALK/PTEN/JUN/FZD2/PTCH1/HDAC2/AGER/TNF/INS",35]
["GO:0009743","response to carbohydrate","26/267","233/18866",3.81220101883186e-16,2.02492762627952e-14,7.25300059461963e-15,"GCLC/PRKACA/PTGS2/APOB/SMARCB1/XBP1/HIF1A/ADNP/OXT/PPARGC1A/SRF/PTK2B/PIK3CA/IL1B/MEN1/LDHA/GLUL/RAC1/POLG/PRKCE/PTEN/LEP/LPL/ADIPOQ/HLA-DRB1/AGER",26]
["GO:0097305","response to alcohol","26/267","234/18866",4.23554274206747e-16,2.22611209590978e-14,7.97361453603616e-15,"BRCA1/FGFR2/OXT/SFRP1/TGFB1/IL2/OPRM1/CNR1/PTK2B/CYP2E1/SOD1/AKT1/SLC6A3/GNRH1/DRD2/CTNNB1/FOS/PRKCE/BCL2L1/PTEN/LEP/NQO1/ADIPOQ/PENK/PTCH1/HDAC2",26]
["GO:0046427","positive regulation of receptor signaling pathway via JAK-STAT","18/267","90/18866",4.45223702063448e-16,2.31562702541958e-14,8.29424418646709e-15,"IGF1/TNFRSF1A/FGFR3/IL2/IFNG/PTK2B/LIF/IL6/IL10/IL18/IL6R/PRL/LEP/ERBB4/F2/CSF1R/HDAC2/TNF",18]
["GO:0051222","positive regulation of protein transport","31/267","354/18866",4.92246492262166e-16,2.5338007586237e-14,9.07571123552273e-15,"CD38/IGF1/ACSL4/PRKACA/PTGS2/GSK3B/P2RX7/MAPK1/XBP1/HIF1A/TGFB1/MAPK8/IL2/IFNG/IL1A/IL1B/GLUL/RAC1/IL6/IL10/TP53/PIK3R1/DRD2/SHH/CDK5/PRKCE/BCL2/LEP/HLA-DRB1/TNF/INS",31]
["GO:0001655","urogenital system development","30/267","330/18866",5.44490902587928e-16,2.77412558838931e-14,9.93652033831246e-15,"FGFR2/GLI2/NOTCH3/DLG1/FGFR1/BAX/ESR1/SFRP1/FGF8/VEGFA/PDGFRB/LIF/SRD5A1/ACE/IL6R/SHH/RET/FBN1/CTNNB1/FADD/GDNF/AR/BCL2/PTEN/BDNF/ADIPOQ/PTCH1/LRRK2/NF1/DLL1",30]
["GO:0070372","regulation of ERK1 and ERK2 cascade","29/267","306/18866",5.71180260569277e-16,2.88071014244687e-14,1.03182909378756e-14,"FGFR2/FGFR3/DLG1/HTR2A/MAPK3/TGFB1/FGF8/CCL2/OPRM1/PDGFRB/DUSP1/PTK2B/IL1B/LIF/APOE/DUSP6/DRD2/BRAF/ATF3/MAP2K1/PTEN/JUN/ERBB4/PTPN11/ADIPOQ/CSF1R/HLA-DRB1/AGER/TNF",29]
["GO:0032147","activation of protein kinase activity","30/267","331/18866",5.91387120090979e-16,2.95279589061426e-14,1.05764917582587e-14,"IGF1/PRKACA/DLG1/P2RX7/MAPK1/ADNP/MAPK3/PRKAR1A/VEGFA/PTK2B/PIK3CA/IL1B/MAP2K2/NGF/DUSP6/SOD1/AKT1/DRD2/IL18/BRAF/IL6R/RET/MAP2K1/ALK/LEP/PTPN11/LRRK2/MTOR/TNF/INS",30]
["GO:0050863","regulation of T cell activation","30/267","332/18866",6.42129390930872e-16,3.17440796922559e-14,1.1370274467864e-14,"IGF1/TNFRSF1B/GLI2/DLG1/XBP1/CCL2/PRKAR1A/IL2/IFNG/IL1A/PIK3CA/IL1B/IDO1/RAC1/IL6/IL10/SOD1/AKT1/PIK3R1/GNRH1/IL18/SHH/CTNNB1/FADD/LEP/PAWR/PTPN11/HLA-DRB1/DPP4/AGER",30]
["GO:0070663","regulation of leukocyte proliferation","26/267","240/18866",7.88001704528681e-16,3.85734559873697e-14,1.38164591949869e-14,"CD38/TAC1/IGF1/TNFRSF1B/DLG1/MAPK1/MAPK3/PRKAR1A/IL2/IL1A/IL1B/IDO1/CRP/IL6/IL10/GNRH1/IL18/SHH/CTNNB1/FADD/BCL2/LEP/PAWR/CSF1R/HLA-DRB1/AGER",26]
["GO:1903706","regulation of hemopoiesis","36/267","498/18866",8.03203798110182e-16,3.88065252938941e-14,1.38999412808091e-14,"CREBBP/GLI2/GNAS/XBP1/EP300/HIF1A/GATA1/SFRP1/TGFB1/IL2/IFNG/IL17A/IL1A/KMT2A/CREB1/PTK2B/IL1B/LIF/SOD1/PIK3R1/IL18/ACE/SHH/FBN1/KMT2D/CTNNB1/FADD/FOS/JUN/ADIPOQ/HLA-DRB1/NF1/DLL1/MTOR/AGER/TNF",36]
["GO:0032943","mononuclear cell proliferation","28/267","286/18866",8.09625519257292e-16,3.88065252938941e-14,1.38999412808091e-14,"CD38/TAC1/IGF1/TNFRSF1B/DLG1/BAX/P2RX7/PRKAR1A/IL2/IL1A/IL1B/IDO1/CRP/IL6/IL10/TP53/GNRH1/IL18/ACE/SHH/CTNNB1/FADD/BCL2/LEP/PAWR/HLA-DRB1/IFNA1/AGER",28]
["GO:0032355","response to estradiol","21/267","141/18866",8.16271120261441e-16,3.88065252938941e-14,1.38999412808091e-14,"CD38/PTGS2/APOB/ESR1/OXT/SFRP1/TGFB1/COL1A1/PPARGC1A/PDGFRB/DUSP1/IL10/ESR2/CYP1A2/SRD5A1/CTNNB1/PTEN/LEP/NQO1/PENK/PTCH1",21]
["GO:1904894","positive regulation of receptor signaling pathway via STAT","18/267","93/18866",8.23851728650665e-16,3.88065252938941e-14,1.38999412808091e-14,"IGF1/TNFRSF1A/FGFR3/IL2/IFNG/PTK2B/LIF/IL6/IL10/IL18/IL6R/PRL/LEP/ERBB4/F2/CSF1R/HDAC2/TNF",18]
["GO:0046425","regulation of receptor signaling pathway via JAK-STAT","21/267","142/18866",9.45969002364165e-16,4.41422731663951e-14,1.58111297099529e-14,"IGF1/TNFRSF1A/FGFR3/IL2/IFNG/PTK2B/LIF/IL6/IL10/IL18/IL6R/CDK5/RET/PRL/LEP/ERBB4/F2/CSF1R/HDAC2/IFNA1/TNF",21]
["GO:0001763","morphogenesis of a branching structure","24/267","201/18866",1.16510976165823e-15,5.38647503699955e-14,1.92935817257049e-14,"FGFR2/GLI2/DLG1/FGFR1/ESR1/SFRP1/FGF8/VDR/TIMELESS/SRF/VEGFA/KRAS/IL10/RERE/DRD2/EDNRA/SHH/CTNNB1/GDNF/AR/BCL2/PTCH1/LRRK2/TNF",24]
["GO:0043405","regulation of MAP kinase activity","30/267","342/18866",1.43921724856482e-15,6.58165611011724e-14,2.35745490657219e-14,"IGF1/FGFR1/P2RX7/MAPK1/HTR2A/MAPK3/SFRP1/TGFB1/VEGFA/PDGFRB/DUSP1/PTK2B/IL1B/MAP2K2/APOE/KRAS/NGF/DUSP6/SOD1/BRAF/DVL3/RET/MAP2K1/ALK/PTPN11/ADIPOQ/LRRK2/NF1/AGER/TNF",30]
["GO:0090132","epithelium migration","31/267","368/18866",1.45271796768499e-15,6.58165611011724e-14,2.35745490657219e-14,"TAC1/GRN/HDAC9/PTGS2/FGFR1/HDAC6/SIRT1/HIF1A/TGFB1/FGF8/IFNG/SRF/VEGFA/PTK2B/PIK3CA/APOE/GLUL/CDH13/AKT1/PLK2/NOS3/MECP2/PRKCE/PTEN/JUN/PTPN11/NF1/DPP4/MTOR/TNF/GPX1",31]
["GO:0090596","sensory organ morphogenesis","27/267","269/18866",1.46317610299021e-15,6.58165611011724e-14,2.35745490657219e-14,"PAX6/COL11A1/FGFR2/GLI2/FGFR1/BAX/MAPK1/HIF1A/MAPK3/FGF8/VEGFA/MFN2/ATF4/COL2A1/SOD1/NTRK2/PRKCI/HESX1/FBN1/CTNNB1/CHD7/BCL2/BDNF/FZD2/HDAC2/NF1/DLL1",27]
["GO:0010721","negative regulation of cell development","30/267","343/18866",1.5577350888018e-15,6.94443865927446e-14,2.48739841717506e-14,"CD38/PAX6/IGF1/NGFR/NOTCH3/GSK3B/REST/TSPO/VEGFA/IL1B/APOE/IL6/TP53/PLK2/GNRH1/SHH/CDK5/FBN1/CTNNB1/BCL2/PTEN/BDNF/ERBB4/F2/DCC/LRRK2/HDAC2/NF1/DLL1/TNF",30]
["GO:0007259","receptor signaling pathway via JAK-STAT","22/267","164/18866",1.5836126080303e-15,6.99732544415512e-14,2.50634170567627e-14,"IGF1/TNFRSF1A/FGFR3/CCL2/IL2/IFNG/PTK2B/LIF/IL6/IL10/IL18/IL6R/CDK5/RET/PRL/LEP/ERBB4/F2/CSF1R/HDAC2/IFNA1/TNF",22]
["GO:1904951","positive regulation of establishment of protein localization","31/267","370/18866",1.68868358156724e-15,7.39613782698705e-14,2.64919058641066e-14,"CD38/IGF1/ACSL4/PRKACA/PTGS2/GSK3B/P2RX7/MAPK1/XBP1/HIF1A/TGFB1/MAPK8/IL2/IFNG/IL1A/IL1B/GLUL/RAC1/IL6/IL10/TP53/PIK3R1/DRD2/SHH/CDK5/PRKCE/BCL2/LEP/HLA-DRB1/TNF/INS",31]
["GO:0001667","ameboidal-type cell migration","35/267","481/18866",1.71735022156436e-15,7.45628665762685e-14,2.67073503564106e-14,"TAC1/GRN/HDAC9/PTGS2/FGFR1/HDAC6/SIRT1/HIF1A/TGFB1/FGF8/IFNG/SRF/VEGFA/PTK2B/PIK3CA/APOE/GLUL/CDH13/AKT1/PLK2/SHH/NOS3/RET/GDNF/MECP2/PRKCE/PTEN/JUN/ERBB4/PTPN11/NF1/DPP4/MTOR/TNF/GPX1",35]
["GO:0071902","positive regulation of protein serine/threonine kinase activity","30/267","345/18866",1.82333010352602e-15,7.84817862664259e-14,2.8111051233128e-14,"IGF1/FGFR1/P2RX7/SIRT1/MAPK1/HTR2A/MAPK3/TGFB1/IFNG/VEGFA/PDGFRB/PTK2B/IL1B/MAP2K2/KRAS/NGF/DUSP6/SOD1/AKT1/BRAF/DVL3/RET/MAP2K1/ALK/PTPN11/ADIPOQ/CSF1R/LRRK2/AGER/TNF",30]
["GO:0048545","response to steroid hormone","30/267","346/18866",1.97183793491826e-15,8.41486052055289e-14,3.01408245742342e-14,"CD38/BRCA1/PTGS2/REST/ESR1/HDAC6/SIRT1/TSPO/EP300/OXT/SFRP1/TGFB1/COL1A1/NR3C1/DUSP1/KRAS/IL6/IL10/ESR2/SRD5A1/GNRH1/NR3C2/SST/S100B/KMT2D/AR/FOS/BCL2/ADIPOQ/TNF",30]
["GO:0009408","response to heat","22/267","166/18866",2.05415731190825e-15,8.69187072742194e-14,3.11330354409644e-14,"GCLC/CREBBP/IGF1/PRKACA/PTGS2/GSK3B/SIRT1/MAPK1/EP300/MAPK3/BAG1/IL1A/SOD1/AKT1/SST/NOS3/VCP/ATP2A2/MAPT/HDAC2/NF1/MTOR",22]
["GO:0090130","tissue migration","31/267","374/18866",2.2750989110781e-15,9.54585618740585e-14,3.41918889864811e-14,"TAC1/GRN/HDAC9/PTGS2/FGFR1/HDAC6/SIRT1/HIF1A/TGFB1/FGF8/IFNG/SRF/VEGFA/PTK2B/PIK3CA/APOE/GLUL/CDH13/AKT1/PLK2/NOS3/MECP2/PRKCE/PTEN/JUN/PTPN11/NF1/DPP4/MTOR/TNF/GPX1",31]
["GO:0031668","cellular response to extracellular stimulus","26/267","253/18866",2.84558410719968e-15,1.184000120604e-13,4.24091877029145e-14,"P2RX7/COMT/SIRT1/MAPK1/XBP1/ADNP/MAPK3/SFRP1/MAPK8/COL1A1/VDR/SRF/ATF4/GLUL/TP53/SRD5A1/ATF3/ALB/FOS/BCL2/LEP/LPL/JUN/PENK/LRRK2/MTOR",26]
["GO:1904892","regulation of receptor signaling pathway via STAT","21/267","151/18866",3.38427996985004e-15,1.39650494954225e-13,5.00208061659436e-14,"IGF1/TNFRSF1A/FGFR3/IL2/IFNG/PTK2B/LIF/IL6/IL10/IL18/IL6R/CDK5/RET/PRL/LEP/ERBB4/F2/CSF1R/HDAC2/IFNA1/TNF",21]
["GO:0034614","cellular response to reactive oxygen species","22/267","170/18866",3.41881939293839e-15,1.3991938712247e-13,5.01171194875093e-14,"HDAC6/SIRT1/MAPK1/MAPK3/MAPK8/SOD2/PDGFRB/MTR/KDM6B/IL6/IL10/SOD1/AKT1/NOS3/FOS/PAWR/JUN/NQO1/MAPT/LRRK2/HDAC2/TNF",22]
["GO:1905952","regulation of lipid localization","22/267","171/18866",3.874636233854e-15,1.56079707212763e-13,5.59055145739792e-14,"PON1/TAC1/APOB/P2RX7/SIRT1/TSPO/OXT/POMC/IL1B/APOE/CRP/IL6/FTO/AKT1/SHH/LEP/LPL/PTPN11/ADIPOQ/PRKN/PTCH1/TNF",22]
["GO:0051341","regulation of oxidoreductase activity","19/267","117/18866",3.87620342366966e-15,1.56079707212763e-13,5.59055145739792e-14,"HDAC6/HIF1A/VDR/IFNG/IL1A/CNR1/PTK2B/IL1B/APOE/KRAS/AKT1/NOS3/GDNF/LEP/PRKN/LRRK2/TNF/INS/HP",19]
["GO:0048015","phosphatidylinositol-mediated signaling","23/267","192/18866",4.36607681766031e-15,1.74398572404623e-13,6.2467069584883e-14,"IGF1/ERBB3/FGFR1/SIRT1/MAPK1/HTR2A/MAPK3/TSC2/PDGFRB/PIK3CA/NGF/AKT1/PIK3R1/NTRK2/IL18/PTEN/LEP/ERBB4/F2/CSF1R/NF1/TNF/INS",23]
["GO:0016570","histone modification","34/267","468/18866",4.7119922722859e-15,1.86722042980345e-13,6.68811601555033e-14,"CREBBP/BRCA1/HDAC9/HDAC4/REST/ATRX/HDAC6/SIRT1/SMARCB1/EP300/MAPK3/MAPK8/PPARGC1A/VEGFA/KMT2A/IL1B/LIF/DNMT1/PER2/KDM6B/PRMT7/MEN1/BRCA2/TP53/KDM6A/CDK5/KMT2D/CTNNB1/MECP2/MTHFR/EHMT1/LRRK2/PAX5/HDAC2",34]
["GO:0014065","phosphatidylinositol 3-kinase signaling","21/267","154/18866",5.07504541649008e-15,1.9952521074437e-13,7.14670713851359e-14,"IGF1/ERBB3/FGFR1/SIRT1/MAPK1/HTR2A/MAPK3/TSC2/PDGFRB/PIK3CA/AKT1/PIK3R1/NTRK2/IL18/PTEN/LEP/ERBB4/F2/NF1/TNF/INS",21]
["GO:0071692","protein localization to extracellular region","34/267","470/18866",5.34331713758223e-15,2.08431113030844e-13,7.46570379667122e-14,"CD38/NOS2/IGF1/HDAC9/ACSL4/REST/P2RX7/XBP1/HIF1A/SFRP1/TGFB1/IL2/IFNG/OPRM1/IL1A/CNR1/IL1B/APOE/PER2/GLUL/RAC1/IL6/IL10/DRD2/FBN1/PRKCE/SNCG/LEP/PTPN11/PRKN/HLA-DRB1/DPP4/TNF/INS",34]
["GO:0048661","positive regulation of smooth muscle cell proliferation","18/267","103/18866",5.47540740504214e-15,2.11927978088181e-13,7.59095649218e-14,"IGF1/FGFR2/HDAC4/PTGS2/NOTCH3/PPARGC1A/PDGFRB/MFN2/DNMT1/IL6/IL10/CDH13/AKT1/IL18/IL6R/JUN/MTOR/TNF",18]
["GO:0097696","receptor signaling pathway via STAT","22/267","174/18866",5.61147453920575e-15,2.15523787494264e-13,7.71975323247819e-14,"IGF1/TNFRSF1A/FGFR3/CCL2/IL2/IFNG/PTK2B/LIF/IL6/IL10/IL18/IL6R/CDK5/RET/PRL/LEP/ERBB4/F2/CSF1R/HDAC2/IFNA1/TNF",22]
["GO:0048017","inositol lipid-mediated signaling","23/267","196/18866",6.86955075915171e-15,2.61829518629347e-13,9.37835816777723e-14,"IGF1/ERBB3/FGFR1/SIRT1/MAPK1/HTR2A/MAPK3/TSC2/PDGFRB/PIK3CA/NGF/AKT1/PIK3R1/NTRK2/IL18/PTEN/LEP/ERBB4/F2/CSF1R/NF1/TNF/INS",23]
["GO:0045637","regulation of myeloid cell differentiation","26/267","263/18866",7.25066786000485e-15,2.74262004734881e-13,9.82367200490291e-14,"CREBBP/GNAS/EP300/HIF1A/GATA1/SFRP1/TGFB1/IFNG/IL17A/KMT2A/CREB1/PTK2B/LIF/PIK3R1/FBN1/KMT2D/CTNNB1/FADD/FOS/JUN/ADIPOQ/HLA-DRB1/NF1/DLL1/MTOR/TNF",26]
["GO:0001819","positive regulation of cytokine production","33/267","447/18866",7.75412080749869e-15,2.91100189412338e-13,1.04267916517137e-13,"CREBBP/BRCA1/PTGS2/P2RX7/XBP1/EP300/HIF1A/TGFB1/IL2/IFNG/IL17A/IL1A/CREB1/IL1B/ATF4/IDO1/IL6/IL10/SOD1/PIK3R1/DRD2/IL18/IL6R/CTNNB1/FADD/LEP/LPL/PTPN11/ADIPOQ/HDAC2/AGER/TNF/INS",33]
["GO:0010631","epithelial cell migration","30/267","365/18866",8.30156995893124e-15,3.09326408992117e-13,1.10796287197362e-13,"TAC1/GRN/HDAC9/PTGS2/FGFR1/HDAC6/SIRT1/HIF1A/TGFB1/IFNG/SRF/VEGFA/PTK2B/PIK3CA/APOE/GLUL/CDH13/AKT1/PLK2/NOS3/MECP2/PRKCE/PTEN/JUN/PTPN11/NF1/DPP4/MTOR/TNF/GPX1",30]
["GO:0051897","positive regulation of protein kinase B signaling","22/267","178/18866",9.08928122119867e-15,3.36168749166259e-13,1.20410828809486e-13,"ERBB3/FGFR2/FGFR3/FGFR1/ESR1/TGFB1/FGF8/PDGFRB/PIK3CA/RAC1/PIK3R1/IL18/FGF17/RET/LEP/ERBB4/PTPN11/MTOR/TNF/GPX1/INS/MC1R",22]
["GO:0019233","sensory perception of pain","18/267","106/18866",9.26865237634106e-15,3.40282215551992e-13,1.21884213524795e-13,"TAC1/PTGS2/P2RX7/COMT/MAPK1/OXT/HTR2A/MAPK3/CCL2/OPRM1/CNR1/IL10/CDK5/MECP2/PENK/CCK/MTOR/MC1R",18]
["GO:1902105","regulation of leukocyte differentiation","27/267","290/18866",9.48142795937821e-15,3.45553064242156e-13,1.237721559968e-13,"GLI2/GNAS/XBP1/SFRP1/TGFB1/IL2/IFNG/IL17A/IL1A/CREB1/IL1B/LIF/SOD1/PIK3R1/IL18/SHH/FBN1/CTNNB1/FADD/FOS/JUN/ADIPOQ/HLA-DRB1/NF1/MTOR/AGER/TNF",27]
["GO:0016569","covalent chromatin modification","34/267","481/18866",1.05452655026431e-14,3.81539932280413e-13,1.36662136453018e-13,"CREBBP/BRCA1/HDAC9/HDAC4/REST/ATRX/HDAC6/SIRT1/SMARCB1/EP300/MAPK3/MAPK8/PPARGC1A/VEGFA/KMT2A/IL1B/LIF/DNMT1/PER2/KDM6B/PRMT7/MEN1/BRCA2/TP53/KDM6A/CDK5/KMT2D/CTNNB1/MECP2/MTHFR/EHMT1/LRRK2/PAX5/HDAC2",34]
["GO:1901653","cellular response to peptide","31/267","398/18866",1.25813378396374e-14,4.51932516786398e-13,1.61875751530056e-13,"GCLC/IGF1/HDAC9/ARID1B/NGFR/PRKACA/GSK3B/SIRT1/XBP1/TSC2/PRKAR1A/TIMELESS/CREB1/PIK3CA/IL1B/MEN1/TP53/AKT1/SRD5A1/PIK3R1/PRKCI/CDK5/FBN1/PTEN/PRL/LEP/LPL/PTPN11/ADIPOQ/AGER/INS",31]
["GO:0032768","regulation of monooxygenase activity","15/267","66/18866",1.73908922173028e-14,6.14100926079226e-13,2.19962151940845e-13,"HIF1A/VDR/IFNG/IL1A/CNR1/PTK2B/IL1B/APOE/KRAS/AKT1/NOS3/GDNF/LEP/TNF/INS",15]
["GO:0019216","regulation of lipid metabolic process","32/267","431/18866",1.74649171847086e-14,6.14100926079226e-13,2.19962151940845e-13,"CREBBP/BRCA1/TNFRSF1A/FGFR3/PTGS2/REST/APOB/SIRT1/TSPO/HTR2A/TGFB1/PPARGC1A/VDR/IFNG/GNB3/PDGFRB/CREB1/CNR1/PTK2B/IL1B/APOE/SOD1/AKT1/PIK3R1/PRKCE/LEP/F2/ADIPOQ/SERPINA3/MTOR/TNF/INS",32]
["GO:0030099","myeloid cell differentiation","32/267","431/18866",1.74649171847086e-14,6.14100926079226e-13,2.19962151940845e-13,"CREBBP/GNAS/SIRT1/EP300/HIF1A/GATA1/SFRP1/TGFB1/IFNG/IL17A/SRF/VEGFA/KMT2A/CREB1/PTK2B/LIF/LBR/PIK3R1/FBN1/KMT2D/CTNNB1/FADD/FOS/JUN/PTPN11/ADIPOQ/CSF1R/HLA-DRB1/NF1/DLL1/MTOR/TNF",32]
["GO:0071867","response to monoamine","18/267","110/18866",1.82086091391066e-14,6.31358232163605e-13,2.26143471691097e-13,"PRKACA/GSK3B/GNAS/MAPK1/HTR2A/MAPK3/PPARGC1A/OPRM1/ATF4/GNAL/SRD5A1/DRD2/ALK/ADIPOQ/PENK/PRKN/LRRK2/HDAC2",18]
["GO:0071869","response to catecholamine","18/267","110/18866",1.82086091391066e-14,6.31358232163605e-13,2.26143471691097e-13,"PRKACA/GSK3B/GNAS/MAPK1/HTR2A/MAPK3/PPARGC1A/OPRM1/ATF4/GNAL/SRD5A1/DRD2/ALK/ADIPOQ/PENK/PRKN/LRRK2/HDAC2",18]
["GO:0033135","regulation of peptidyl-serine phosphorylation","20/267","145/18866",1.84577534194142e-14,6.35583191883691e-13,2.27656791721123e-13,"PTGS2/BAX/HDAC6/TGFB1/IFNG/VEGFA/PIK3CA/LIF/NGF/IL6/AKT1/NTRK2/BRAF/RET/BCL2/PTEN/BDNF/IFNA1/DMD/TNF",20]
["GO:0009306","protein secretion","33/267","462/18866",1.99388311362477e-14,6.8188071139236e-13,2.44239899787201e-13,"CD38/NOS2/IGF1/HDAC9/ACSL4/REST/P2RX7/XBP1/HIF1A/SFRP1/TGFB1/IL2/IFNG/OPRM1/IL1A/CNR1/IL1B/APOE/PER2/GLUL/RAC1/IL6/IL10/DRD2/PRKCE/SNCG/LEP/PTPN11/PRKN/HLA-DRB1/DPP4/TNF/INS",33]
["GO:0035592","establishment of protein localization to extracellular region","33/267","463/18866",2.12057177431229e-14,7.20273120349744e-13,2.57991510530367e-13,"CD38/NOS2/IGF1/HDAC9/ACSL4/REST/P2RX7/XBP1/HIF1A/SFRP1/TGFB1/IL2/IFNG/OPRM1/IL1A/CNR1/IL1B/APOE/PER2/GLUL/RAC1/IL6/IL10/DRD2/PRKCE/SNCG/LEP/PTPN11/PRKN/HLA-DRB1/DPP4/TNF/INS",33]
["GO:1903037","regulation of leukocyte cell-cell adhesion","28/267","329/18866",2.8770358410014e-14,9.7061080771081e-13,3.4765888292044e-13,"IGF1/GLI2/DLG1/XBP1/CCL2/PRKAR1A/IL2/IFNG/IL1A/PIK3CA/IL1B/IDO1/RAC1/IL6/IL10/AKT1/PIK3R1/GNRH1/IL18/SHH/FADD/LEP/PAWR/PTPN11/HLA-DRB1/DPP4/AGER/TNF",28]
["GO:1901216","positive regulation of neuron death","17/267","97/18866",3.02389999226537e-14,1.01331091687121e-12,3.62953450148984e-13,"GRN/HDAC4/GSK3B/REST/BAX/IFNG/ATF4/TP53/CDK5/CTNNB1/FOS/JUN/NQO1/MAPT/NF1/MTOR/TNF",17]
["GO:0060249","anatomical structure homeostasis","33/267","469/18866",3.05823809077284e-14,1.01554176230495e-12,3.63752507016374e-13,"CD38/PTGS2/ATRX/BAX/GNAS/P2RX7/MAPK1/HIF1A/GATA1/MAPK3/SRF/VEGFA/PDGFRB/CNR1/PTK2B/KRAS/RAC1/IL6/COL2A1/BRCA2/SOD1/ALB/NOS3/CDK5/CTNNB1/BCL2/CALB2/PTPN11/CSF1R/PRKN/SERPINA3/NF1/DMD",33]
["GO:0002573","myeloid leukocyte differentiation","23/267","210/18866",3.09157516263475e-14,1.01554176230495e-12,3.63752507016374e-13,"GNAS/SIRT1/GATA1/SFRP1/TGFB1/IFNG/IL17A/VEGFA/CREB1/LIF/LBR/PIK3R1/FBN1/CTNNB1/FADD/FOS/JUN/ADIPOQ/CSF1R/HLA-DRB1/NF1/MTOR/TNF",23]
["GO:0006109","regulation of carbohydrate metabolic process","23/267","210/18866",3.09157516263475e-14,1.01554176230495e-12,3.63752507016374e-13,"IGF1/POU1F1/HDAC4/GSK3B/P2RX7/SIRT1/EP300/HIF1A/HTR2A/TGFB1/PPARGC1A/IFNG/GNB3/POMC/PTK2B/TP53/AKT1/PRKCE/LEP/ADIPOQ/PRKN/MTOR/INS",23]
["GO:0035264","multicellular organism growth","20/267","150/18866",3.58201488623972e-14,1.16895426973823e-12,4.18702668849074e-13,"IGF1/POU1F1/ATRX/GNAS/EP300/CREB1/PIK3CA/FTO/TP53/SOD1/SLC6A3/KDM6A/DRD2/AR/CHD7/BCL2/PRL/PTPN11/PTCH1/MTOR",20]
["GO:0008202","steroid metabolic process","28/267","332/18866",3.61305712650234e-14,1.17142819692378e-12,4.19588794116711e-13,"PON1/FGFR1/REST/APOB/ESR1/COMT/SIRT1/CYP2D6/TSPO/PPARGC1A/VDR/IFNG/GNB3/IL1B/APOE/CYP2E1/CYP27A1/CYP1A2/SOD1/LBR/SRD5A1/CYP3A4/SHH/CYP2C19/MECP2/LEP/CYP2B6/TNF",28]
["GO:0035265","organ growth","22/267","191/18866",4.00606393102407e-14,1.29046949726472e-12,4.62227682092353e-13,"IGF1/FGFR2/FGFR3/FGFR1/ESR1/MAPK1/FGF8/PRKAR1A/PDGFRB/DUSP6/SOD1/AKT1/PDLIM5/SHH/AR/BCL2/PTEN/LEP/ERBB4/PTPN11/DLL1/MTOR",22]
["GO:0001822","kidney development","26/267","283/18866",4.16806076289258e-14,1.32554951523074e-12,4.74792841847435e-13,"FGFR2/GLI2/NOTCH3/DLG1/FGFR1/BAX/SFRP1/FGF8/VEGFA/PDGFRB/LIF/ACE/IL6R/SHH/RET/FBN1/CTNNB1/FADD/GDNF/BCL2/BDNF/ADIPOQ/PTCH1/LRRK2/NF1/DLL1",26]
["GO:0046651","lymphocyte proliferation","26/267","283/18866",4.16806076289258e-14,1.32554951523074e-12,4.74792841847435e-13,"CD38/TAC1/IGF1/TNFRSF1B/DLG1/BAX/P2RX7/PRKAR1A/IL2/IL1A/IL1B/IDO1/IL6/IL10/TP53/GNRH1/IL18/SHH/CTNNB1/FADD/BCL2/LEP/PAWR/HLA-DRB1/IFNA1/AGER",26]
["GO:0090276","regulation of peptide hormone secretion","23/267","213/18866",4.20196623727001e-14,1.32787452042336e-12,4.75625625391189e-13,"CD38/NOS2/ACSL4/REST/HIF1A/SFRP1/IFNG/CNR1/IL1B/PER2/GLUL/RAC1/IL6/DRD2/PRKCE/CHD7/LEP/PTPN11/PRKN/HLA-DRB1/DPP4/TNF/INS",23]
["GO:0043434","response to peptide hormone","32/267","447/18866",4.80399153576742e-14,1.50857419736395e-12,5.40349660328954e-13,"GCLC/HDAC9/ARID1B/PRKACA/PTGS2/GSK3B/SIRT1/XBP1/OXT/TSC2/COL1A1/PRKAR1A/CREB1/PIK3CA/IL1B/MEN1/IL10/AKT1/SRD5A1/PIK3R1/GNRH1/PRKCI/INPPL1/FBN1/PTEN/PRL/LEP/LPL/PTPN11/ADIPOQ/MTOR/INS",32]
["GO:0001659","temperature homeostasis","21/267","174/18866",6.08331359307589e-14,1.89837404813924e-12,6.79970381226048e-13,"PTGS2/GNAS/OXT/HTR2A/PPARGC1A/VEGFA/IL1A/MFN2/CNR1/IL1B/ATF4/PER2/KDM6B/FTO/DRD2/IL18/LEP/EHMT1/ADIPOQ/TNF/GPX1",21]
["GO:0042098","T cell proliferation","22/267","195/18866",6.17393242460823e-14,1.91468599975583e-12,6.85813088552427e-13,"IGF1/TNFRSF1B/DLG1/BAX/P2RX7/PRKAR1A/IL2/IL1A/IL1B/IDO1/IL6/IL10/TP53/GNRH1/IL18/SHH/CTNNB1/FADD/LEP/PAWR/HLA-DRB1/AGER",22]
["GO:0043406","positive regulation of MAP kinase activity","25/267","264/18866",6.59603743641726e-14,2.03296388395255e-12,7.28178531804609e-13,"IGF1/FGFR1/P2RX7/MAPK1/HTR2A/MAPK3/TGFB1/VEGFA/PDGFRB/PTK2B/IL1B/MAP2K2/KRAS/NGF/DUSP6/SOD1/BRAF/DVL3/RET/MAP2K1/ALK/PTPN11/LRRK2/AGER/TNF",25]
["GO:0007623","circadian rhythm","23/267","218/18866",6.92932108716124e-14,2.12258283363166e-12,7.60278755381785e-13,"NOS2/NGFR/GSK3B/SIRT1/EP300/MAPK8/PPARGC1A/TIMELESS/KMT2A/CREB1/ATF4/PER2/TP53/SRD5A1/NTRK2/DRD2/PTEN/LEP/BDNF/JUN/ADIPOQ/HDAC2/MTOR",23]
["GO:0030098","lymphocyte differentiation","29/267","368/18866",7.06081171942965e-14,2.14967273872636e-12,7.69981971200961e-13,"HDAC9/POU1F1/HDAC4/GLI2/BAX/XBP1/EP300/SFRP1/IL2/IFNG/SRF/IL1A/PTK2B/IL1B/IL6/IL10/TP53/SOD1/PIK3R1/IL18/SHH/CTNNB1/FADD/CHD7/BCL2/LEP/IFNA1/DLL1/MTOR",29]
["GO:0042326","negative regulation of phosphorylation","33/267","484/18866",7.44925664842459e-14,2.25419020882327e-12,8.07418631302927e-13,"PAX6/HDAC4/DLG1/BAX/P2RX7/SIRT1/TSC2/SFRP1/TGFB1/PRKAR1A/IL2/PPARGC1A/IFNG/DUSP1/IL1B/LIF/APOE/PPP1R1B/MEN1/DUSP6/AKT1/CDKN2A/DRD2/ATF3/PTEN/JUN/ADIPOQ/PRKN/MAPT/LRRK2/NF1/MTOR/DMD",33]
["GO:0060291","long-term synaptic potentiation","16/267","87/18866",7.97234949673335e-14,2.39794825525239e-12,8.58910703547874e-13,"GSK3B/MAPK1/CREB1/PTK2B/APOE/PLK2/NTRK2/DRD2/S100B/SQSTM1/MECP2/PTEN/CALB2/NF1/AGER/INS",16]
["GO:0072001","renal system development","26/267","292/18866",8.72841592948423e-14,2.60963956502484e-12,9.34735497270325e-13,"FGFR2/GLI2/NOTCH3/DLG1/FGFR1/BAX/SFRP1/FGF8/VEGFA/PDGFRB/LIF/ACE/IL6R/SHH/RET/FBN1/CTNNB1/FADD/GDNF/BCL2/BDNF/ADIPOQ/PTCH1/LRRK2/NF1/DLL1",26]
["GO:0045785","positive regulation of cell adhesion","31/267","428/18866",8.99718451907157e-14,2.67398466093597e-12,9.57782988590388e-13,"IGF1/GLI2/GSK3B/XBP1/OLFM4/SFRP1/CCL2/IL2/IFNG/VEGFA/IL1A/PTK2B/PIK3CA/IL1B/LIF/RAC1/IL6/IL10/CDH13/AKT1/PIK3R1/IL18/SHH/RET/FADD/PRKCE/LEP/PTPN11/DPP4/AGER/TNF",31]
["GO:0031669","cellular response to nutrient levels","23/267","221/18866",9.29409666506401e-14,2.72973086168615e-12,9.77750478881966e-13,"COMT/SIRT1/MAPK1/XBP1/MAPK3/SFRP1/MAPK8/COL1A1/VDR/SRF/ATF4/GLUL/TP53/SRD5A1/ATF3/ALB/BCL2/LEP/LPL/JUN/PENK/LRRK2/MTOR",23]
["GO:0032944","regulation of mononuclear cell proliferation","23/267","221/18866",9.29409666506401e-14,2.72973086168615e-12,9.77750478881966e-13,"CD38/TAC1/IGF1/TNFRSF1B/DLG1/PRKAR1A/IL2/IL1A/IL1B/IDO1/CRP/IL6/IL10/GNRH1/IL18/SHH/CTNNB1/FADD/BCL2/LEP/PAWR/HLA-DRB1/AGER",23]
["GO:0051961","negative regulation of nervous system development","27/267","319/18866",9.73000659549752e-14,2.84104812463854e-12,1.01762272734689e-12,"CD38/PAX6/NGFR/PRKACA/NOTCH3/GSK3B/REST/TSPO/IL1B/APOE/IL6/TP53/PLK2/GNRH1/SHH/CDK5/CTNNB1/PTEN/BDNF/ERBB4/F2/DCC/LRRK2/HDAC2/NF1/DLL1/TNF",27]
["GO:0043279","response to alkaloid","17/267","104/18866",1.00641827968187e-13,2.92153864561139e-12,1.04645327856763e-12,"TAC1/OXT/HTR2A/PPARGC1A/OPRM1/CNR1/PTK2B/PPP1R1B/SLC6A3/DRD2/CDK5/FADD/PRKCE/BCL2L1/PENK/HDAC2/MTOR",17]
["GO:0016049","cell growth","33/267","490/18866",1.05335542846891e-13,3.04011771927473e-12,1.08892660357084e-12,"CD38/IGF1/GSK3B/HDAC6/SIRT1/ADNP/SFRP1/TGFB1/IL2/SRF/VEGFA/PTK2B/APOE/NGF/ADAM10/ESR2/TP53/AKT1/CDKN2A/PDLIM5/CDK5/KMT2D/CTNNB1/BCL2/BDNF/F2/PRKN/MAPT/DCC/MTOR/L1CAM/MEG3/INS",33]
["GO:0051091","positive regulation of DNA-binding transcription factor activity","25/267","270/18866",1.10241710752453e-13,3.16343024015515e-12,1.13309538153912e-12,"ZIC2/HDAC4/ESR1/SMARCB1/EP300/PPARGC1A/SRF/VEGFA/IL1B/KRAS/IL6/IL10/ESR2/AKT1/IL18/PRKCI/SHH/CTNNB1/AR/ALK/PTEN/FZD2/AGER/TNF/INS",25]
["GO:0050768","negative regulation of neurogenesis","26/267","295/18866",1.10990848171124e-13,3.16672745667671e-12,1.13427639724956e-12,"CD38/PAX6/NGFR/NOTCH3/GSK3B/REST/TSPO/IL1B/APOE/IL6/TP53/PLK2/GNRH1/SHH/CDK5/CTNNB1/PTEN/BDNF/ERBB4/F2/DCC/LRRK2/HDAC2/NF1/DLL1/TNF",26]
["GO:0008625","extrinsic apoptotic signaling pathway via death domain receptors","16/267","89/18866",1.15836781073944e-13,3.28621049944433e-12,1.17707351103248e-12,"BRCA1/TNFRSF1A/GSK3B/BAX/SFRP1/NGF/PIK3R1/ATF3/NOS3/FADD/BCL2L1/BCL2/PTEN/NF1/TNF/GPX1",16]
["GO:0050796","regulation of insulin secretion","21/267","181/18866",1.34148599788404e-13,3.78420315674295e-12,1.35544734487362e-12,"CD38/NOS2/ACSL4/REST/HIF1A/SFRP1/IFNG/CNR1/IL1B/PER2/GLUL/RAC1/IL6/DRD2/PRKCE/LEP/PTPN11/PRKN/HLA-DRB1/DPP4/TNF",21]
["GO:0002761","regulation of myeloid leukocyte differentiation","18/267","123/18866",1.35952199109625e-13,3.81353556266492e-12,1.36595379235513e-12,"GNAS/SFRP1/TGFB1/IFNG/IL17A/CREB1/LIF/PIK3R1/FBN1/CTNNB1/FADD/FOS/JUN/ADIPOQ/HLA-DRB1/NF1/MTOR/TNF",18]
["GO:2000379","positive regulation of reactive oxygen species metabolic process","17/267","106/18866",1.39458094262178e-13,3.89002382486621e-12,1.3933507918344e-12,"HDAC4/PTGS2/TSPO/TGFB1/IFNG/PDGFRB/PTK2B/IL1B/CRP/TP53/SOD1/AKT1/LEP/F2/MAPT/MTOR/TNF",17]
["GO:0051235","maintenance of location","27/267","324/18866",1.4163872177926e-13,3.92890076579913e-12,1.40727595498808e-12,"PRKACA/APOB/BAX/P2RX7/SIRT1/TSPO/HTR2A/PTK2B/IL1B/APOE/SYNE1/CRP/IL6/IL10/FTO/AKT1/DRD2/ALB/CDK5/FBN1/PRKCE/CHD7/LEP/LPL/F2/DMD/TNF",27]
["GO:0030879","mammary gland development","19/267","142/18866",1.49051192686163e-13,4.11167185128183e-12,1.47274193878331e-12,"FGFR2/GLI2/BAX/ESR1/MAPK1/XBP1/HIF1A/VDR/VEGFA/CREB1/BRCA2/AKT1/SLC6A3/AR/PRL/ERBB4/CSF1R/PTCH1/GPX1",19]
["GO:0022612","gland morphogenesis","18/267","124/18866",1.57045310380587e-13,4.29457669078142e-12,1.53825583135076e-12,"PAX6/FGFR2/GLI2/FGFR1/BAX/ESR1/XBP1/SFRP1/TGFB1/FGF8/VDR/IL6/SHH/AR/BCL2/CSF1R/PTCH1/TNF",18]
["GO:0060541","respiratory system development","22/267","204/18866",1.574018694999e-13,4.29457669078142e-12,1.53825583135076e-12,"FGFR2/GLI2/FGFR1/MAPK1/EP300/MAPK3/FGF8/TIMELESS/SRF/VEGFA/PDGFRB/CREB1/LIF/KRAS/CYP1A2/HESX1/SHH/NOS3/CTNNB1/MAP2K1/CHD7/TNF",22]
["GO:2001237","negative regulation of extrinsic apoptotic signaling pathway","17/267","107/18866",1.63721723543282e-13,4.44273133506309e-12,1.59132270194529e-12,"GCLC/BRCA1/IGF1/GSK3B/GATA1/IL1A/IL1B/COL2A1/AKT1/NOS3/FADD/GDNF/AR/BCL2L1/BCL2/TNF/GPX1",17]
["GO:0022407","regulation of cell-cell adhesion","31/267","439/18866",1.77389005405111e-13,4.78758542696065e-12,1.7148444960642e-12,"IGF1/GLI2/DLG1/XBP1/TGFB1/CCL2/PRKAR1A/IL2/IFNG/VEGFA/IL1A/PIK3CA/IL1B/IDO1/RAC1/IL6/IL10/AKT1/PIK3R1/GNRH1/IL18/SHH/FADD/LEP/PAWR/PTPN11/ADIPOQ/HLA-DRB1/DPP4/AGER/TNF",31]
["GO:1903201","regulation of oxidative stress-induced cell death","15/267","77/18866",1.99007850748588e-13,5.31980595277058e-12,1.90547826193665e-12,"REST/HDAC6/SIRT1/HIF1A/SOD2/ATF4/IL10/SOD1/AKT1/CTNNB1/PAWR/PRKN/LRRK2/GPX1/INS",15]
["GO:1900407","regulation of cellular response to oxidative stress","16/267","92/18866",1.99239678183076e-13,5.31980595277058e-12,1.90547826193665e-12,"REST/HDAC6/SIRT1/HIF1A/SOD2/ATF4/IL10/SOD1/AKT1/CTNNB1/PAWR/PRKN/LRRK2/TNF/GPX1/INS",16]
["GO:0034284","response to monosaccharide","22/267","207/18866",2.1270745709082e-13,5.64919326199183e-12,2.02346007613272e-12,"GCLC/PRKACA/PTGS2/SMARCB1/XBP1/HIF1A/PPARGC1A/SRF/PTK2B/PIK3CA/MEN1/LDHA/GLUL/RAC1/POLG/PRKCE/PTEN/LEP/LPL/ADIPOQ/HLA-DRB1/AGER",22]
["GO:0007612","learning","19/267","145/18866",2.19420421288158e-13,5.79664636768134e-12,2.07627566565626e-12,"TAC1/PTGS2/COMT/HIF1A/SRF/CREB1/PPP1R1B/KRAS/NTRK2/DRD2/SORCS3/CDK5/MECP2/FOS/JUN/PRKN/CCK/NF1/MTOR",19]
["GO:0033138","positive regulation of peptidyl-serine phosphorylation","17/267","109/18866",2.24475978489869e-13,5.89899242421007e-12,2.11293455653344e-12,"PTGS2/HDAC6/TGFB1/IFNG/VEGFA/PIK3CA/LIF/NGF/IL6/AKT1/NTRK2/BRAF/RET/BCL2/BDNF/IFNA1/TNF",17]
["GO:0001933","negative regulation of protein phosphorylation","31/267","444/18866",2.39827855177595e-13,6.24459069294627e-12,2.23672290413225e-12,"PAX6/DLG1/BAX/P2RX7/SIRT1/TSC2/SFRP1/TGFB1/PRKAR1A/IL2/PPARGC1A/IFNG/DUSP1/IL1B/LIF/APOE/PPP1R1B/MEN1/DUSP6/AKT1/CDKN2A/DRD2/ATF3/PTEN/JUN/ADIPOQ/PRKN/LRRK2/NF1/MTOR/DMD",31]
["GO:0014066","regulation of phosphatidylinositol 3-kinase signaling","18/267","127/18866",2.40128462456576e-13,6.24459069294627e-12,2.23672290413225e-12,"IGF1/ERBB3/FGFR1/SIRT1/MAPK1/MAPK3/TSC2/PDGFRB/PIK3CA/PIK3R1/NTRK2/IL18/PTEN/LEP/ERBB4/F2/TNF/INS",18]
["GO:0032770","positive regulation of monooxygenase activity","11/267","31/18866",2.44768731253094e-13,6.33228121837668e-12,2.26813239377697e-12,"HIF1A/VDR/IFNG/PTK2B/IL1B/APOE/KRAS/AKT1/GDNF/TNF/INS",11]
["GO:0042542","response to hydrogen peroxide","19/267","146/18866",2.49087422852047e-13,6.41079124897047e-12,2.29625356172343e-12,"HDAC6/SIRT1/COL1A1/PDGFRB/DUSP1/PTK2B/KDM6B/LDHA/IL6/IL10/SOD1/BCL2/PAWR/JUN/NQO1/LRRK2/HDAC2/GPX1/HP",19]
["GO:0061138","morphogenesis of a branching epithelium","21/267","187/18866",2.56860540849856e-13,6.57694707929914e-12,2.35576819921137e-12,"FGFR2/GLI2/DLG1/FGFR1/ESR1/SFRP1/FGF8/VDR/TIMELESS/SRF/VEGFA/KRAS/IL10/EDNRA/SHH/CTNNB1/GDNF/AR/BCL2/PTCH1/TNF",21]
["GO:0042692","muscle cell differentiation","29/267","390/18866",3.08833496330921e-13,7.86737575091985e-12,2.81798125814305e-12,"IGF1/HDAC9/FGFR2/HDAC4/SIRT1/XBP1/TGFB1/PRKAR1A/SOD2/SRF/VEGFA/PDGFRB/DNMT1/SYNE1/KDM6B/KRAS/AKT1/PDLIM5/SHH/CTNNB1/MECP2/BCL2/ATP2A2/BDNF/NEB/DLL1/MTOR/DMD/GPX1",29]
["GO:0043393","regulation of protein binding","22/267","211/18866",3.15268772581281e-13,7.99054305329105e-12,2.86209802092224e-12,"HDAC4/PRKACA/GSK3B/BAX/EP300/ADNP/MAPK3/MAPK8/STMN1/APOE/PRMT7/MEN1/IL10/AKT1/PLK2/ACE/CDK5/ATP2A2/BDNF/ADIPOQ/PRKN/LRRK2",22]
["GO:0007159","leukocyte cell-cell adhesion","28/267","364/18866",3.54461730159648e-13,8.93852231660163e-12,3.20165060893802e-12,"IGF1/GLI2/DLG1/XBP1/CCL2/PRKAR1A/IL2/IFNG/IL1A/PIK3CA/IL1B/IDO1/RAC1/IL6/IL10/AKT1/PIK3R1/GNRH1/IL18/SHH/FADD/LEP/PAWR/PTPN11/HLA-DRB1/DPP4/AGER/TNF",28]
["GO:0010821","regulation of mitochondrion organization","21/267","191/18866",3.90732829651622e-13,9.75505726673448e-12,3.49412172750943e-12,"GCLC/IGF1/GSK3B/BAX/HDAC6/TSPO/EP300/HIF1A/TSC2/MAPK8/PPARGC1A/MFN2/TP53/AKT1/SQSTM1/BCL2L1/BCL2/PRKN/MAPT/LRRK2/GPX1",21]
["GO:1903829","positive regulation of cellular protein localization","27/267","338/18866",3.90749339745022e-13,9.75505726673448e-12,3.49412172750943e-12,"NGFR/PRKACA/PTGS2/DLG1/GSK3B/MAPK1/TGFB1/MAPK8/IFNG/IL1B/LIF/TP53/AKT1/PIK3R1/SQSTM1/PRKCI/SHH/CDK5/PRKCE/BCL2/LEP/ERBB4/F2/PRKN/MAPT/TNF/INS",27]
["GO:0001894","tissue homeostasis","24/267","261/18866",4.07210500092302e-13,1.01154329699545e-11,3.6232031403866e-12,"CD38/PTGS2/BAX/GNAS/P2RX7/GATA1/SRF/VEGFA/PDGFRB/PTK2B/KRAS/RAC1/IL6/COL2A1/SOD1/ALB/NOS3/CTNNB1/BCL2/PTPN11/CSF1R/SERPINA3/NF1/DMD",24]
["GO:0035148","tube formation","19/267","150/18866",4.09539505051095e-13,1.01229244986144e-11,3.62588649860245e-12,"FGFR2/PRKACA/HIF1A/TSC2/SFRP1/TGFB1/FGF8/VEGFA/KDM6A/DVL3/HESX1/SHH/RET/CTNNB1/GDNF/MTHFR/FZD2/MED12/PTCH1",19]
["GO:0046777","protein autophosphorylation","23/267","237/18866",4.12185136118976e-13,1.01381299736061e-11,3.63133288185709e-12,"VRK2/FGFR2/FGFR3/PRKACA/FGFR1/GSK3B/MAPK3/VEGFA/PDGFRB/PTK2B/MAP2K2/AKT1/NTRK2/ACE/CDK5/ALK/JUN/ERBB4/ADIPOQ/CSF1R/LRRK2/MTOR/INS",23]
["GO:0007584","response to nutrient","20/267","171/18866",4.47678857367907e-13,1.09571594844998e-11,3.92469751634713e-12,"GCLC/ACSL4/PTGS2/XBP1/TSPO/SFRP1/COL1A1/VDR/SRF/CNR1/LDHA/SST/PTEN/LEP/LPL/MTHFR/NQO1/ADIPOQ/PENK/MTOR",20]
["GO:0050727","regulation of inflammatory response","30/267","425/18866",4.52326681903997e-13,1.10169127938861e-11,3.94610029553217e-12,"TAC1/NOS2/IGF1/TNFRSF1B/GRN/TNFRSF1A/PTGS2/ESR1/IL2/IFNG/IL17A/CNR1/IL1B/APOE/IDO1/IL6/IL10/SOD1/IL18/LEP/LPL/F2/ADIPOQ/LRRK2/HLA-DRB1/AGER/TNF/GPX1/NEAT1/INS",30]
["GO:0016331","morphogenesis of embryonic epithelium","19/267","151/18866",4.62619648896486e-13,1.11725823743871e-11,4.00185890859492e-12,"FGFR2/PRKACA/GLI2/HIF1A/TSC2/SFRP1/TGFB1/FGF8/KDM6A/DVL3/SHH/RET/CTNNB1/GDNF/AR/MTHFR/FZD2/MED12/PTCH1",19]
["GO:0070374","positive regulation of ERK1 and ERK2 cascade","22/267","215/18866",4.63193381033073e-13,1.11725823743871e-11,4.00185890859492e-12,"FGFR2/FGFR3/HTR2A/MAPK3/TGFB1/FGF8/CCL2/OPRM1/PDGFRB/PTK2B/APOE/DRD2/BRAF/MAP2K1/PTEN/JUN/ERBB4/PTPN11/CSF1R/HLA-DRB1/AGER/TNF",22]
["GO:0036473","cell death in response to oxidative stress","16/267","97/18866",4.70514140171191e-13,1.12946014513209e-11,4.04556439347598e-12,"REST/HDAC6/SIRT1/HIF1A/SOD2/ATF4/IL10/SOD1/AKT1/CTNNB1/BCL2/PAWR/PRKN/LRRK2/GPX1/INS",16]
["GO:0060485","mesenchyme development","25/267","290/18866",5.55631535861736e-13,1.32740108064959e-11,4.75456046048395e-12,"ERBB3/FGFR2/FGFR1/GSK3B/MAPK1/HIF1A/MAPK3/SFRP1/TGFB1/FGF8/COL1A1/PDGFRB/IL1B/IL6/EDNRA/SHH/NOS3/RET/CTNNB1/GDNF/BCL2/PTEN/ERBB4/HDAC2/MTOR",25]
["GO:0045834","positive regulation of lipid metabolic process","19/267","153/18866",5.88644315390558e-13,1.39957193654526e-11,5.01306612455417e-12,"TNFRSF1A/FGFR3/PTGS2/HTR2A/TGFB1/PPARGC1A/IFNG/PDGFRB/CREB1/PTK2B/IL1B/APOE/AKT1/PRKCE/F2/ADIPOQ/MTOR/TNF/INS",19]
["GO:0062013","positive regulation of small molecule metabolic process","19/267","154/18866",6.63078505539206e-13,1.56907629296552e-11,5.62020644006541e-12,"NOS2/IGF1/POU1F1/PTGS2/P2RX7/COMT/SIRT1/HIF1A/HTR2A/PPARGC1A/IFNG/IL1B/AKT1/NOS3/VCP/PRKCE/ADIPOQ/TNF/INS",19]
["GO:0050670","regulation of lymphocyte proliferation","22/267","219/18866",6.74800090861223e-13,1.58928153475004e-11,5.69257872082035e-12,"CD38/TAC1/IGF1/TNFRSF1B/DLG1/PRKAR1A/IL2/IL1A/IL1B/IDO1/IL6/IL10/GNRH1/IL18/SHH/CTNNB1/FADD/BCL2/LEP/PAWR/HLA-DRB1/AGER",22]
["GO:0071241","cellular response to inorganic substance","22/267","221/18866",8.11988337450472e-13,1.90340740323484e-11,6.81773256895652e-12,"PTGS2/ATRX/FUS/MAPK1/TSPO/MAPK3/MAPK8/PPARGC1A/TIMELESS/MTR/CREB1/ATF4/CYP1A2/SOD1/AKT1/BRAF/SHH/FOS/JUN/NQO1/PRKN/LRRK2",22]
["GO:1901861","regulation of muscle tissue development","19/267","156/18866",8.39095989351284e-13,1.95775994150979e-11,7.0124155725914e-12,"IGF1/HDAC9/ERBB3/FGFR2/HDAC4/FGFR1/MAPK1/TGFB1/FGF8/PPARGC1A/CREB1/S100B/SHH/CTNNB1/BCL2/PTEN/ERBB4/DLL1/MTOR",19]
["GO:0030324","lung development","20/267","177/18866",8.6173927031118e-13,2.00123915193662e-11,7.16815187397158e-12,"FGFR2/GLI2/FGFR1/MAPK1/EP300/MAPK3/FGF8/TIMELESS/SRF/VEGFA/PDGFRB/CREB1/LIF/KRAS/CYP1A2/SHH/NOS3/CTNNB1/MAP2K1/TNF",20]
["GO:1902882","regulation of response to oxidative stress","16/267","101/18866",9.02091576527718e-13,2.08525150074208e-11,7.4690720688138e-12,"REST/HDAC6/SIRT1/HIF1A/SOD2/ATF4/IL10/SOD1/AKT1/CTNNB1/PAWR/PRKN/LRRK2/TNF/GPX1/INS",16]
["GO:0045666","positive regulation of neuron differentiation","28/267","380/18866",1.01389364959267e-12,2.3328898582563e-11,8.35607718000455e-12,"GRN/NGFR/GLI2/FGFR1/REST/EP300/ADNP/IL2/SRF/VEGFA/CNR1/PTK2B/APOE/NGF/NTRK2/DVL3/PRKCI/RET/MAP2K1/ALK/BCL2/PTEN/BDNF/PRKN/MAPT/TCF4/MTOR/L1CAM",28]
["GO:0042531","positive regulation of tyrosine phosphorylation of STAT protein","14/267","71/18866",1.07824454122579e-12,2.45829908417368e-11,8.80527505668161e-12,"IGF1/TNFRSF1A/FGFR3/IL2/IFNG/LIF/IL6/IL18/IL6R/LEP/ERBB4/CSF1R/HDAC2/TNF",14]
["GO:0061180","mammary gland epithelium development","14/267","71/18866",1.07824454122579e-12,2.45829908417368e-11,8.80527505668161e-12,"FGFR2/GLI2/BAX/ESR1/MAPK1/HIF1A/VDR/BRCA2/AKT1/AR/ERBB4/CSF1R/PTCH1/GPX1",14]
["GO:0009746","response to hexose","21/267","202/18866",1.1759631856986e-12,2.66890190281505e-11,9.55962417465034e-12,"GCLC/PRKACA/PTGS2/SMARCB1/XBP1/HIF1A/PPARGC1A/SRF/PTK2B/PIK3CA/MEN1/LDHA/GLUL/RAC1/POLG/PRKCE/PTEN/LPL/ADIPOQ/HLA-DRB1/AGER",21]
["GO:1902107","positive regulation of leukocyte differentiation","19/267","159/18866",1.18663696104363e-12,2.68094042827641e-11,9.6027444477882e-12,"GLI2/GNAS/XBP1/TGFB1/IL2/IFNG/IL17A/IL1A/CREB1/IL1B/LIF/IL18/SHH/FADD/FOS/JUN/HLA-DRB1/AGER/TNF",19]
["GO:0030323","respiratory tube development","20/267","181/18866",1.31435793619669e-12,2.95612125019372e-11,1.05884027197637e-11,"FGFR2/GLI2/FGFR1/MAPK1/EP300/MAPK3/FGF8/TIMELESS/SRF/VEGFA/PDGFRB/CREB1/LIF/KRAS/CYP1A2/SHH/NOS3/CTNNB1/MAP2K1/TNF",20]
["GO:1901342","regulation of vasculature development","30/267","444/18866",1.38870942242592e-12,3.10933907900118e-11,1.11372070271496e-11,"BRCA1/GRN/HDAC9/NGFR/PTGS2/SIRT1/XBP1/HIF1A/SFRP1/SOD2/VEGFA/IL1A/PTK2B/IL1B/DNMT1/GLUL/IL6/IL10/ADAM10/PLK2/IL6R/NOS3/CTNNB1/MECP2/CXCL8/PRL/LEP/NF1/DLL1/TNF",30]
["GO:1903708","positive regulation of hemopoiesis","21/267","204/18866",1.42581510367277e-12,3.17816732707061e-11,1.13837399489664e-11,"GLI2/GNAS/XBP1/HIF1A/GATA1/TGFB1/IL2/IFNG/IL17A/IL1A/CREB1/IL1B/LIF/IL18/SHH/FADD/FOS/JUN/HLA-DRB1/AGER/TNF",21]
["GO:0021782","glial cell development","17/267","122/18866",1.49877846130385e-12,3.31123931738501e-11,1.18603847496751e-11,"GRN/IFNG/IL1B/KRAS/IL6/SOD1/AKT1/NTRK2/SHH/CDK5/PTEN/MED12/MAPT/NF1/DLL1/AGER/TNF",17]
["GO:0045471","response to ethanol","17/267","122/18866",1.49877846130385e-12,3.31123931738501e-11,1.18603847496751e-11,"FGFR2/IL2/OPRM1/CNR1/PTK2B/CYP2E1/SOD1/SLC6A3/GNRH1/DRD2/PRKCE/PTEN/LEP/NQO1/ADIPOQ/PENK/HDAC2",17]
["GO:0048762","mesenchymal cell differentiation","22/267","229/18866",1.66937929636595e-12,3.67189904262343e-11,1.31522162046174e-11,"FGFR2/FGFR1/GSK3B/MAPK1/HIF1A/MAPK3/SFRP1/TGFB1/FGF8/COL1A1/IL1B/IL6/EDNRA/SHH/RET/CTNNB1/GDNF/BCL2/PTEN/ERBB4/HDAC2/MTOR",22]
["GO:0006953","acute-phase response","12/267","47/18866",1.69742822619163e-12,3.71721891814685e-11,1.33145455046149e-11,"PTGS2/IL1A/CNR1/IL1B/CRP/IL6/IL6R/F2/SERPINA3/TNF/INS/HP",12]
["GO:2000027","regulation of animal organ morphogenesis","23/267","254/18866",1.76761826197897e-12,3.85402531967729e-11,1.38045664311757e-11,"NGFR/FGFR2/FGFR1/BAX/ESR1/XBP1/SFRP1/FGF8/VDR/VEGFA/LIF/RAC1/DVL3/SHH/CTNNB1/GDNF/AR/BCL2/BDNF/FZD2/GPC6/MED12/TNF",23]
["GO:0046890","regulation of lipid biosynthetic process","21/267","207/18866",1.89561449566126e-12,4.11207101072814e-11,1.47288491197721e-11,"BRCA1/TNFRSF1A/PTGS2/REST/APOB/SIRT1/TSPO/HTR2A/PPARGC1A/VDR/IFNG/CREB1/IL1B/APOE/SOD1/AKT1/LEP/ADIPOQ/MTOR/TNF/INS",21]
["GO:0031331","positive regulation of cellular catabolic process","28/267","390/18866",1.90244022326898e-12,4.11207101072814e-11,1.47288491197721e-11,"GCLC/IGF1/TNFRSF1B/GSK3B/BAX/P2RX7/HDAC6/SIRT1/HIF1A/HTR2A/MAPK3/TSC2/IFNG/MFN2/PTK2B/IL1B/APOE/IL6/FTO/AKT1/PLK2/VCP/PTEN/PRKN/LIN28B/LRRK2/TNF/INS",28]
["GO:0045598","regulation of fat cell differentiation","18/267","143/18866",1.92554226372355e-12,4.144065742574e-11,1.48434496645477e-11,"PTGS2/HDAC6/SIRT1/XBP1/HTR2A/SFRP1/TGFB1/GNB3/CREB1/IL6/FTO/AKT1/LEP/LPL/ADIPOQ/MTOR/TNF/INS",18]
["GO:0071868","cellular response to monoamine stimulus","16/267","106/18866",1.95294688037178e-12,4.16712127081038e-11,1.49260312629404e-11,"PRKACA/GSK3B/GNAS/MAPK1/HTR2A/MAPK3/OPRM1/ATF4/GNAL/SRD5A1/DRD2/ALK/ADIPOQ/PRKN/LRRK2/HDAC2",16]
["GO:0071870","cellular response to catecholamine stimulus","16/267","106/18866",1.95294688037178e-12,4.16712127081038e-11,1.49260312629404e-11,"PRKACA/GSK3B/GNAS/MAPK1/HTR2A/MAPK3/OPRM1/ATF4/GNAL/SRD5A1/DRD2/ALK/ADIPOQ/PRKN/LRRK2/HDAC2",16]
["GO:0001558","regulation of cell growth","29/267","420/18866",1.97117315109387e-12,4.1881138482603e-11,1.50012236672273e-11,"CD38/IGF1/GSK3B/SIRT1/ADNP/SFRP1/TGFB1/IL2/SRF/VEGFA/PTK2B/APOE/NGF/ADAM10/ESR2/TP53/AKT1/CDKN2A/CDK5/BCL2/BDNF/F2/PRKN/MAPT/DCC/MTOR/L1CAM/MEG3/INS",29]
["GO:0042220","response to cocaine","12/267","48/18866",2.23501006271426e-12,4.70860980722881e-11,1.68655656076017e-11,"OXT/HTR2A/OPRM1/CNR1/PTK2B/PPP1R1B/SLC6A3/DRD2/CDK5/FADD/HDAC2/MTOR",12]
["GO:2001239","regulation of extrinsic apoptotic signaling pathway in absence of ligand","12/267","48/18866",2.23501006271426e-12,4.70860980722881e-11,1.68655656076017e-11,"FGFR1/GATA1/IL1A/IL1B/COL2A1/AKT1/RET/GDNF/BCL2L1/BCL2/NF1/TNF",12]
["GO:0030072","peptide hormone secretion","23/267","257/18866",2.25773547510312e-12,4.73650135596213e-11,1.69654691384352e-11,"CD38/NOS2/ACSL4/REST/HIF1A/SFRP1/IFNG/CNR1/IL1B/PER2/GLUL/RAC1/IL6/DRD2/PRKCE/CHD7/LEP/PTPN11/PRKN/HLA-DRB1/DPP4/TNF/INS",23]
["GO:0009612","response to mechanical stimulus","21/267","209/18866",2.2857300449658e-12,4.77516741193064e-11,1.71039654102484e-11,"GCLC/COL11A1/TNFRSF1A/HDAC4/PTGS2/P2RX7/HTR2A/MAPK3/MAPK8/COL1A1/PTK2B/IL1B/RAC1/AKT1/DRD2/FADD/FOS/JUN/PTPN11/PTCH1/DMD",21]
["GO:0045444","fat cell differentiation","22/267","235/18866",2.81074411065653e-12,5.84751889354503e-11,2.09449747544099e-11,"PTGS2/HDAC6/SIRT1/XBP1/EP300/HTR2A/SFRP1/TGFB1/PPARGC1A/GNB3/CREB1/PER2/IL6/FTO/AKT1/LEP/LPL/ADIPOQ/MTOR/TNF/GPX1/INS",22]
["GO:0042129","regulation of T cell proliferation","19/267","167/18866",2.88275584868204e-12,5.97244811305786e-11,2.13924533169285e-11,"IGF1/TNFRSF1B/DLG1/PRKAR1A/IL2/IL1A/IL1B/IDO1/IL6/IL10/GNRH1/IL18/SHH/CTNNB1/FADD/LEP/PAWR/HLA-DRB1/AGER",19]
["GO:0051048","negative regulation of secretion","20/267","190/18866",3.26741624978916e-12,6.74140881619721e-11,2.41467603670804e-11,"TNFRSF1B/HDAC9/ERBB3/TNFRSF1A/REST/COMT/OXT/SFRP1/OPRM1/CNR1/IL1B/LIF/APOE/DRD2/LEP/PTPN11/ADIPOQ/PRKN/NF1/INS",20]
["GO:0030073","insulin secretion","21/267","213/18866",3.3023298836325e-12,6.78540457159551e-11,2.43043468585299e-11,"CD38/NOS2/ACSL4/REST/HIF1A/SFRP1/IFNG/CNR1/IL1B/PER2/GLUL/RAC1/IL6/DRD2/PRKCE/LEP/PTPN11/PRKN/HLA-DRB1/DPP4/TNF",21]
["GO:1903409","reactive oxygen species biosynthetic process","17/267","128/18866",3.32833942367872e-12,6.81081915673273e-11,2.43953782606995e-11,"NOS2/HDAC4/PTGS2/TSPO/IFNG/PTK2B/IL1B/RAC1/IL10/CYP1A2/SOD1/AKT1/NOS3/NQO1/MTOR/TNF/INS",17]
["GO:0010675","regulation of cellular carbohydrate metabolic process","18/267","148/18866",3.49065630199762e-12,7.11381506770372e-11,2.54806661958924e-11,"IGF1/POU1F1/HDAC4/GSK3B/SIRT1/EP300/PPARGC1A/GNB3/POMC/PTK2B/TP53/AKT1/PRKCE/LEP/ADIPOQ/PRKN/MTOR/INS",18]
["GO:0031056","regulation of histone modification","18/267","149/18866",3.9205202903728e-12,7.95738122350869e-11,2.8502199286878e-11,"BRCA1/ATRX/SIRT1/SMARCB1/MAPK3/MAPK8/PPARGC1A/VEGFA/KMT2A/IL1B/LIF/DNMT1/TP53/CTNNB1/MECP2/MTHFR/LRRK2/PAX5",18]
["GO:0030307","positive regulation of cell growth","19/267","171/18866",4.41008258457376e-12,8.91479447156955e-11,3.19315163485652e-11,"CD38/IGF1/ADNP/SFRP1/IL2/SRF/VEGFA/PTK2B/NGF/ADAM10/AKT1/BCL2/BDNF/F2/PRKN/MAPT/MTOR/L1CAM/INS",19]
["GO:0010506","regulation of autophagy","26/267","347/18866",4.6959053567837e-12,9.45429655097622e-11,3.38639354888604e-11,"PRKACA/GSK3B/HDAC6/SIRT1/XBP1/TSPO/EP300/HIF1A/MAPK3/TSC2/MAPK8/IFNG/MFN2/PIK3CA/GFAP/IL10/TP53/AKT1/PLK2/CDK5/BCL2/LEP/PRKN/MAPT/LRRK2/MTOR",26]
["GO:0050714","positive regulation of protein secretion","19/267","172/18866",4.89561828915369e-12,9.79572020809214e-11,3.50868661042271e-11,"CD38/IGF1/ACSL4/P2RX7/XBP1/HIF1A/TGFB1/IL2/IFNG/IL1A/GLUL/RAC1/IL6/IL10/DRD2/PRKCE/HLA-DRB1/TNF/INS",19]
["GO:1902893","regulation of pri-miRNA transcription by RNA polymerase II","12/267","51/18866",4.90472672145611e-12,9.79572020809214e-11,3.50868661042271e-11,"NGFR/HDAC4/HIF1A/TGFB1/SRF/NR3C1/IL10/TP53/FOS/PRL/JUN/TNF",12]
["GO:1902895","positive regulation of pri-miRNA transcription by RNA polymerase II","11/267","40/18866",5.97120425893205e-12,1.18781764401784e-10,4.25459259212646e-11,"NGFR/HIF1A/TGFB1/SRF/NR3C1/IL10/TP53/FOS/PRL/JUN/TNF",11]
["GO:0016202","regulation of striated muscle tissue development","18/267","153/18866",6.18256801118022e-12,1.22498262221519e-10,4.38771221846082e-11,"IGF1/HDAC9/ERBB3/FGFR2/HDAC4/FGFR1/MAPK1/TGFB1/FGF8/CREB1/S100B/SHH/CTNNB1/BCL2/PTEN/ERBB4/DLL1/MTOR",18]
["GO:0072175","epithelial tube formation","17/267","133/18866",6.26186379139014e-12,1.23578995693324e-10,4.42642254278005e-11,"FGFR2/PRKACA/HIF1A/TSC2/SFRP1/TGFB1/FGF8/KDM6A/DVL3/HESX1/RET/CTNNB1/GDNF/MTHFR/FZD2/MED12/PTCH1",17]
["GO:0050999","regulation of nitric-oxide synthase activity","12/267","52/18866",6.29663002276555e-12,1.23775880723104e-10,4.43347468241967e-11,"HIF1A/IL1A/CNR1/PTK2B/IL1B/APOE/KRAS/AKT1/NOS3/LEP/TNF/INS",12]
["GO:0009749","response to glucose","20/267","197/18866",6.40769029065685e-12,1.25465088710783e-10,4.49397969198183e-11,"GCLC/PRKACA/SMARCB1/XBP1/HIF1A/PPARGC1A/SRF/PTK2B/PIK3CA/MEN1/LDHA/GLUL/RAC1/POLG/PRKCE/PTEN/LPL/ADIPOQ/HLA-DRB1/AGER",20]
["GO:0071216","cellular response to biotic stimulus","22/267","246/18866",7.01638756558757e-12,1.36846965292886e-10,4.90166220145283e-11,"NOS2/TNFRSF1B/GSK3B/MAPK1/XBP1/TSPO/MAPK3/TGFB1/MAPK8/CCL2/PPARGC1A/IL1A/IL1B/IL6/IL10/TP53/AKT1/IL18/NOS3/CXCL8/PRKCE/TNF",22]
["GO:0042391","regulation of membrane potential","29/267","443/18866",7.32000947364404e-12,1.42213257984065e-10,5.09387511600296e-11,"GCLC/TAC1/GABRA3/DLG1/GSK3B/BAX/P2RX7/TSPO/OPRM1/CNR1/PTK2B/SOD1/AKT1/NTRK2/DRD2/CDK5/VCP/MECP2/BCL2L1/BCL2/PTEN/ATP2A2/BDNF/JUN/PRKN/MAPT/CCK/LRRK2/DMD",29]
["GO:0001701","in utero embryonic development","27/267","383/18866",7.39669954461915e-12,1.43146204753037e-10,5.12729193239818e-11,"IGF1/FGFR2/GLI2/FGFR1/APOB/MAPK1/HIF1A/GATA1/SRF/VEGFA/PDGFRB/MFN2/LIF/IL10/ADAM10/BRCA2/TP53/AKT1/KDM6A/EDNRA/NOS3/CTNNB1/MAP2K1/AR/CHD7/BCL2L1/PTCH1",27]
["GO:0048754","branching morphogenesis of an epithelial tube","18/267","155/18866",7.72333062800007e-12,1.48890308206967e-10,5.33303748708478e-11,"FGFR2/GLI2/DLG1/ESR1/FGF8/VDR/TIMELESS/SRF/VEGFA/KRAS/EDNRA/SHH/CTNNB1/GDNF/AR/BCL2/PTCH1/TNF",18]
["GO:0061614","pri-miRNA transcription by RNA polymerase II","12/267","53/18866",8.03804383135671e-12,1.54361357115246e-10,5.52900261922067e-11,"NGFR/HDAC4/HIF1A/TGFB1/SRF/NR3C1/IL10/TP53/FOS/PRL/JUN/TNF",12]
["GO:0007162","negative regulation of cell adhesion","24/267","301/18866",8.76462708387411e-12,1.67029706220547e-10,5.98276473101732e-11,"ERBB3/DLG1/TGFB1/COL1A1/PRKAR1A/IL2/VEGFA/DUSP1/IDO1/MEN1/IL10/ADAM10/CDH13/AKT1/PIK3R1/GNRH1/CDKN2A/SHH/PTEN/PAWR/PTPN11/ADIPOQ/HLA-DRB1/NF1",24]
["GO:0010632","regulation of epithelial cell migration","24/267","301/18866",8.76462708387411e-12,1.67029706220547e-10,5.98276473101732e-11,"TAC1/GRN/HDAC9/PTGS2/FGFR1/HDAC6/SIRT1/HIF1A/TGFB1/IFNG/VEGFA/PTK2B/APOE/GLUL/AKT1/PLK2/NOS3/MECP2/PRKCE/PTEN/JUN/NF1/MTOR/TNF",24]
["GO:0048562","embryonic organ morphogenesis","24/267","302/18866",9.40249380637453e-12,1.78504378613034e-10,6.3937710534442e-11,"PAX6/COL11A1/FGFR2/GLI2/DLG1/FGFR1/GNAS/MAPK1/HIF1A/MAPK3/FGF8/SRF/COL2A1/SOD1/KDM6A/HESX1/SHH/FBN1/CTNNB1/CHD7/FZD2/MED12/PAX5/DLL1",24]
["GO:0048634","regulation of muscle organ development","18/267","157/18866",9.61562665241565e-12,1.81859181346634e-10,6.5139352800854e-11,"IGF1/HDAC9/ERBB3/FGFR2/HDAC4/FGFR1/MAPK1/TGFB1/FGF8/CREB1/S100B/SHH/CTNNB1/BCL2/PTEN/ERBB4/DLL1/MTOR",18]
["GO:0071375","cellular response to peptide hormone stimulus","25/267","330/18866",9.71584877937049e-12,1.8306125643546e-10,6.55699188724944e-11,"GCLC/HDAC9/ARID1B/PRKACA/GSK3B/SIRT1/XBP1/TSC2/PRKAR1A/CREB1/PIK3CA/IL1B/MEN1/AKT1/SRD5A1/PIK3R1/PRKCI/FBN1/PTEN/PRL/LEP/LPL/PTPN11/ADIPOQ/INS",25]
["GO:0030534","adult behavior","17/267","137/18866",1.01785930562664e-11,1.91059079435857e-10,6.84346244661519e-11,"HTR2A/OPRM1/NPY/PPP1R1B/DRD2/CDK5/FADD/GDNF/MECP2/ALK/CHD7/PTEN/SNCG/LEP/PRKN/PAX5/HDAC2",17]
["GO:0071214","cellular response to abiotic stimulus","25/267","331/18866",1.0378658375856e-11,1.93360601756153e-10,6.92589967815372e-11,"GCLC/CREBBP/TNFRSF1A/HDAC4/PTGS2/REST/BAX/SIRT1/TSPO/EP300/MAPK3/SFRP1/MAPK8/COL1A1/IL1B/ATF4/RAC1/TP53/AKT1/PIK3R1/FADD/BCL2L1/PTEN/PTPN11/MC1R",25]
["GO:0104004","cellular response to environmental stimulus","25/267","331/18866",1.0378658375856e-11,1.93360601756153e-10,6.92589967815372e-11,"GCLC/CREBBP/TNFRSF1A/HDAC4/PTGS2/REST/BAX/SIRT1/TSPO/EP300/MAPK3/SFRP1/MAPK8/COL1A1/IL1B/ATF4/RAC1/TP53/AKT1/PIK3R1/FADD/BCL2L1/PTEN/PTPN11/MC1R",25]
["GO:0008361","regulation of cell size","19/267","181/18866",1.21470439899083e-11,2.25465392719748e-10,8.075847285797e-11,"GSK3B/P2RX7/ADNP/GNB3/SRF/VEGFA/CREB1/APOE/NGF/RAC1/AKT1/CDK5/RET/PTEN/BDNF/MAPT/DCC/MTOR/L1CAM",19]
["GO:0009896","positive regulation of catabolic process","29/267","454/18866",1.33021232385595e-11,2.45990745667139e-10,8.81103601649614e-11,"GCLC/IGF1/TNFRSF1B/GSK3B/BAX/P2RX7/HDAC6/SIRT1/HIF1A/HTR2A/MAPK3/TSC2/IFNG/MFN2/PTK2B/IL1B/APOE/IL6/FTO/AKT1/PLK2/VCP/PRKCE/PTEN/PRKN/LIN28B/LRRK2/TNF/INS",29]
["GO:0031346","positive regulation of cell projection organization","27/267","394/18866",1.42221361180188e-11,2.62033673938258e-10,9.38567071839735e-11,"GRN/NGFR/HDAC4/FGFR1/P2RX7/EP300/ADNP/IL2/SRF/VEGFA/CNR1/PTK2B/APOE/NGF/RAC1/NTRK2/DVL3/PRKCI/RET/MAP2K1/ALK/BDNF/PRKN/MAPT/MTOR/L1CAM/INS",27]
["GO:0019932","second-messenger-mediated signaling","29/267","456/18866",1.47987713977461e-11,2.71655388194656e-10,9.73030673559237e-11,"NOS2/IGF1/ERBB3/HDAC4/PRKACA/GSK3B/GNAS/P2RX7/ADNP/PRKAR1A/OPRM1/VEGFA/CNR1/PTK2B/PDE11A/APOE/CDH13/GNAL/DRD2/NOS3/CXCL8/ATP2A2/MAPT/LRRK2/MTOR/DMD/TNF/INS/MC1R",29]
["GO:0001649","osteoblast differentiation","21/267","231/18866",1.5697639106251e-11,2.86052233786537e-10,1.02459811146832e-10,"IGF1/FGFR2/HDAC4/PRKACA/GLI2/REST/GNAS/SFRP1/COL1A1/ATF4/MEN1/IL6/AKT1/IL6R/SHH/CTNNB1/PENK/PTCH1/NF1/TNF/TWIST2",21]
["GO:0048738","cardiac muscle tissue development","21/267","231/18866",1.5697639106251e-11,2.86052233786537e-10,1.02459811146832e-10,"IGF1/COL11A1/ERBB3/FGFR2/FGFR1/MAPK1/TGFB1/FGF8/PRKAR1A/SRF/VEGFA/PDGFRB/CREB1/KDM6B/PDLIM5/CHD7/PTEN/ERBB4/NEB/DLL1/MTOR",21]
["GO:0042509","regulation of tyrosine phosphorylation of STAT protein","14/267","86/18866",1.6828395953994e-11,3.04435438399609e-10,1.0904441161646e-10,"IGF1/TNFRSF1A/FGFR3/IL2/IFNG/LIF/IL6/IL18/IL6R/LEP/ERBB4/CSF1R/HDAC2/TNF",14]
["GO:1901863","positive regulation of muscle tissue development","14/267","86/18866",1.6828395953994e-11,3.04435438399609e-10,1.0904441161646e-10,"IGF1/ERBB3/FGFR2/FGFR1/MAPK1/TGFB1/PPARGC1A/CREB1/SHH/CTNNB1/BCL2/ERBB4/DLL1/MTOR",14]
["GO:0071222","cellular response to lipopolysaccharide","20/267","208/18866",1.7463074524454e-11,3.14776646572559e-10,1.12748484199306e-10,"NOS2/TNFRSF1B/MAPK1/XBP1/TSPO/MAPK3/TGFB1/MAPK8/CCL2/PPARGC1A/IL1A/IL1B/IL6/IL10/AKT1/IL18/NOS3/CXCL8/PRKCE/TNF",20]
["GO:0007411","axon guidance","23/267","284/18866",1.76693152815429e-11,3.17348529499078e-10,1.13669695809699e-10,"PAX6/NGFR/GLI2/NOTCH3/MAPK1/MAPK3/FGF8/VEGFA/PIK3CA/RAC1/PIK3R1/NCAM1/SHH/CDK5/OTX2/RET/GDNF/BDNF/PTPN11/CSF1R/PTCH1/DCC/L1CAM",23]
["GO:0097485","neuron projection guidance","23/267","285/18866",1.89803155094871e-11,3.39672814834656e-10,1.21665934920274e-10,"PAX6/NGFR/GLI2/NOTCH3/MAPK1/MAPK3/FGF8/VEGFA/PIK3CA/RAC1/PIK3R1/NCAM1/SHH/CDK5/OTX2/RET/GDNF/BDNF/PTPN11/CSF1R/PTCH1/DCC/L1CAM",23]
["GO:0014823","response to activity","13/267","71/18866",1.90969774445383e-11,3.40540029930642e-10,1.21976558940867e-10,"GCLC/HIF1A/OXT/PPARGC1A/CREB1/KDM6B/IL6/IL10/SRD5A1/PTEN/LEP/ADIPOQ/MTOR",13]
["GO:0021537","telencephalon development","22/267","259/18866",1.94449679074696e-11,3.45511476021336e-10,1.23757259692043e-10,"PAX6/GSK3B/BAX/HIF1A/FGF8/SRF/NPY/KDM6B/SRD5A1/NTRK2/DRD2/SHH/CDK5/CTNNB1/ALK/CHD7/PTEN/ERBB4/CSF1R/LRRK2/PAX5/NF1",22]
["GO:0045862","positive regulation of proteolysis","26/267","370/18866",1.98542863858806e-11,3.51533517463482e-10,1.25914268643566e-10,"GCLC/TNFRSF1B/GRN/NGFR/GSK3B/REST/BAX/SIRT1/MAPK3/IFNG/PTK2B/IL1B/APOE/NGF/AKT1/PLK2/VCP/FADD/PTEN/PRKN/MAPT/CCK/LRRK2/HDAC2/AGER/TNF",26]
["GO:0043542","endothelial cell migration","23/267","286/18866",2.03823254096707e-11,3.5960759989571e-10,1.28806289272943e-10,"GRN/HDAC9/PTGS2/FGFR1/SIRT1/HIF1A/TGFB1/SRF/VEGFA/PTK2B/PIK3CA/APOE/GLUL/CDH13/AKT1/PLK2/NOS3/MECP2/PTEN/NF1/DPP4/TNF/GPX1",23]
["GO:0002683","negative regulation of immune system process","29/267","463/18866",2.13928662726776e-11,3.76107680631969e-10,1.34716381754186e-10,"GRN/DLG1/SFRP1/TGFB1/CCL2/PRKAR1A/IL2/CNR1/DUSP1/PTK2B/IDO1/IL10/AKT1/PIK3R1/GNRH1/DRD2/SHH/FBN1/CTNNB1/FADD/PAWR/ADIPOQ/HLA-DRB1/NF1/DPP4/DLL1/TNF/GPX1/INS",29]
["GO:0008217","regulation of blood pressure","19/267","187/18866",2.16185217519628e-11,3.78741330201931e-10,1.35659717291172e-10,"TAC1/NOS2/PTGS2/OXT/GNB3/SOD2/POMC/CNR1/NPY/SOD1/DRD2/EDNRA/ACE/NOS3/MECP2/AR/LEP/ADIPOQ/DLL1",19]
["GO:1903039","positive regulation of leukocyte cell-cell adhesion","21/267","235/18866",2.17605587752976e-11,3.79896748129583e-10,1.36073571436255e-10,"IGF1/GLI2/XBP1/CCL2/IL2/IFNG/IL1A/PIK3CA/IL1B/RAC1/IL6/AKT1/PIK3R1/IL18/SHH/FADD/LEP/PTPN11/DPP4/AGER/TNF",21]
["GO:0014068","positive regulation of phosphatidylinositol 3-kinase signaling","14/267","88/18866",2.32567996850308e-11,4.04603487203341e-10,1.44923171336392e-10,"IGF1/ERBB3/FGFR1/SIRT1/PDGFRB/PIK3CA/PIK3R1/NTRK2/IL18/LEP/ERBB4/F2/TNF/INS",14]
["GO:0061448","connective tissue development","22/267","262/18866",2.43859502115567e-11,4.22774477105218e-10,1.51431759537408e-10,"COL11A1/FGFR3/GLI2/FGFR1/GNAS/SIRT1/XBP1/HIF1A/MAPK3/TGFB1/COL1A1/PPARGC1A/SRF/PDGFRB/PIK3CA/COL2A1/FTO/IL6R/CTNNB1/LEP/PTPN11/COL11A2",22]
["GO:1900408","negative regulation of cellular response to oxidative stress","12/267","58/18866",2.52354149750322e-11,4.34484230932192e-10,1.55626025562903e-10,"REST/SIRT1/HIF1A/SOD2/ATF4/IL10/AKT1/CTNNB1/PRKN/LRRK2/GPX1/INS",12]
["GO:1903202","negative regulation of oxidative stress-induced cell death","12/267","58/18866",2.52354149750322e-11,4.34484230932192e-10,1.55626025562903e-10,"REST/SIRT1/HIF1A/SOD2/ATF4/IL10/AKT1/CTNNB1/PRKN/LRRK2/GPX1/INS",12]
["GO:0034605","cellular response to heat","16/267","125/18866",2.59712340231565e-11,4.4561639683031e-10,1.59613407868847e-10,"CREBBP/PRKACA/PTGS2/GSK3B/SIRT1/MAPK1/EP300/MAPK3/BAG1/IL1A/VCP/ATP2A2/MAPT/HDAC2/NF1/MTOR",16]
["GO:1902692","regulation of neuroblast proliferation","10/267","34/18866",2.64910290378534e-11,4.52978452006857e-10,1.62250390538259e-10,"PAX6/HIF1A/VEGFA/TP53/DRD2/SHH/CTNNB1/BDNF/LRRK2/NF1",10]
["GO:0010976","positive regulation of neuron projection development","23/267","290/18866",2.70234093092133e-11,4.58938376465653e-10,1.64385150076453e-10,"GRN/NGFR/FGFR1/EP300/ADNP/IL2/SRF/VEGFA/CNR1/PTK2B/APOE/NGF/NTRK2/DVL3/PRKCI/RET/MAP2K1/ALK/BDNF/PRKN/MAPT/MTOR/L1CAM",23]
["GO:0097193","intrinsic apoptotic signaling pathway","23/267","290/18866",2.70234093092133e-11,4.58938376465653e-10,1.64385150076453e-10,"BRCA1/TNFRSF1B/TNFRSF1A/PTGS2/BAX/SIRT1/XBP1/EP300/HIF1A/SOD2/ATF4/BRCA2/TP53/SOD1/AKT1/PIK3R1/BCL2L1/BCL2/PRKN/LRRK2/TNF/GPX1/INS",23]
["GO:0007260","tyrosine phosphorylation of STAT protein","14/267","89/18866",2.7252650925504e-11,4.61262664647598e-10,1.65217676797257e-10,"IGF1/TNFRSF1A/FGFR3/IL2/IFNG/LIF/IL6/IL18/IL6R/LEP/ERBB4/CSF1R/HDAC2/TNF",14]
["GO:0003018","vascular process in circulatory system","19/267","190/18866",2.86045882713361e-11,4.82509152833721e-10,1.72827864413229e-10,"GCLC/CD38/PTGS2/ABCB1/HTR2A/TGFB1/SOD2/VEGFA/APOE/PER2/CRP/SOD1/AKT1/EDNRA/ACE/NOS3/LEP/GPX1/INS",19]
["GO:0006006","glucose metabolic process","20/267","214/18866",2.93862140495152e-11,4.92367002514192e-10,1.76358804910372e-10,"IGF1/GSK3B/SIRT1/EP300/PPARGC1A/GNB3/POMC/PIK3CA/ATF4/PER2/TP53/AKT1/ATF3/INPPL1/LEP/ADIPOQ/PRKN/MTOR/TNF/INS",20]
["GO:0050870","positive regulation of T cell activation","20/267","214/18866",2.93862140495152e-11,4.92367002514192e-10,1.76358804910372e-10,"IGF1/GLI2/XBP1/CCL2/IL2/IFNG/IL1A/PIK3CA/IL1B/RAC1/IL6/AKT1/PIK3R1/IL18/SHH/FADD/LEP/PTPN11/DPP4/AGER",20]
["GO:0051881","regulation of mitochondrial membrane potential","13/267","74/18866",3.3123375814922e-11,5.53127141952861e-10,1.98122216192756e-10,"GCLC/BAX/P2RX7/TSPO/SOD1/AKT1/VCP/BCL2L1/BCL2/PRKN/MAPT/CCK/LRRK2",13]
["GO:0044262","cellular carbohydrate metabolic process","23/267","294/18866",3.56588869333676e-11,5.93482741527682e-10,2.12577013683479e-10,"IGF1/POU1F1/HDAC4/GSK3B/SIRT1/EP300/PPARGC1A/GNB3/POMC/PTK2B/IDUA/PER2/TP53/AKT1/BRAF/MECP2/PRKCE/PTEN/LEP/ADIPOQ/PRKN/MTOR/INS",23]
["GO:0034103","regulation of tissue remodeling","14/267","91/18866",3.71919275445167e-11,6.16941176843096e-10,2.2097948906499e-10,"CD38/BAX/P2RX7/SFRP1/TGFB1/IL2/VDR/IL6/TP53/IL18/LEP/CSF1R/NF1/AGER",14]
["GO:0002793","positive regulation of peptide secretion","19/267","193/18866",3.76505608931008e-11,6.20426569436476e-10,2.22227906747884e-10,"CD38/IGF1/ACSL4/P2RX7/XBP1/HIF1A/TGFB1/IL2/IFNG/IL1A/GLUL/RAC1/IL6/IL10/DRD2/PRKCE/HLA-DRB1/TNF/INS",19]
["GO:0071248","cellular response to metal ion","19/267","193/18866",3.76505608931008e-11,6.20426569436476e-10,2.22227906747884e-10,"PTGS2/FUS/MAPK1/TSPO/MAPK3/MAPK8/PPARGC1A/CREB1/ATF4/CYP1A2/SOD1/AKT1/BRAF/SHH/FOS/JUN/NQO1/PRKN/LRRK2",19]
["GO:0015850","organic hydroxy compound transport","22/267","268/18866",3.79968109285112e-11,6.2407262159887e-10,2.23533870386221e-10,"PON1/TAC1/APOB/SIRT1/TSPO/OXT/HTR2A/POMC/CNR1/APOE/TOR1A/SLC6A3/DRD2/SHH/GDNF/MECP2/SNCG/LEP/PTPN11/ADIPOQ/PRKN/PTCH1",22]
["GO:0010823","negative regulation of mitochondrion organization","12/267","60/18866",3.86168870899847e-11,6.30111494249326e-10,2.25696908035377e-10,"GCLC/IGF1/TSPO/TSC2/PPARGC1A/TP53/AKT1/BCL2L1/PRKN/MAPT/LRRK2/GPX1",12]
["GO:1902883","negative regulation of response to oxidative stress","12/267","60/18866",3.86168870899847e-11,6.30111494249326e-10,2.25696908035377e-10,"REST/SIRT1/HIF1A/SOD2/ATF4/IL10/AKT1/CTNNB1/PRKN/LRRK2/GPX1/INS",12]
["GO:0014074","response to purine-containing compound","17/267","149/18866",3.97650806679358e-11,6.46733054641705e-10,2.31650512788695e-10,"PTGS2/P2RX7/OXT/COL1A1/PPARGC1A/DUSP1/PTK2B/IL1B/LDHA/SOD1/SLC6A3/SRD5A1/FOS/PTEN/ADIPOQ/PENK/HDAC2",17]
["GO:0031058","positive regulation of histone modification","14/267","92/18866",4.33183797581524e-11,7.02235941988491e-10,2.51530851705745e-10,"BRCA1/SIRT1/SMARCB1/MAPK3/PPARGC1A/VEGFA/KMT2A/IL1B/LIF/DNMT1/TP53/CTNNB1/MECP2/LRRK2",14]
["GO:1905475","regulation of protein localization to membrane","19/267","195/18866",4.50922463408869e-11,7.28626491844816e-10,2.60983568499972e-10,"DLG1/TGFB1/MAPK8/IFNG/ADAM10/TP53/AKT1/PIK3R1/SQSTM1/PRKCI/CDK5/AR/PRKCE/BCL2L1/BCL2/GPC6/PRKN/TNF/INS",19]
["GO:0008306","associative learning","13/267","76/18866",4.71362624297673e-11,7.5675677913771e-10,2.7105943431435e-10,"TAC1/HIF1A/SRF/CREB1/PPP1R1B/KRAS/DRD2/CDK5/MECP2/FOS/CCK/NF1/MTOR",13]
["GO:0033555","multicellular organismal response to stress","13/267","76/18866",4.71362624297673e-11,7.5675677913771e-10,2.7105943431435e-10,"TAC1/COMT/TSPO/APOE/IDO1/RET/MECP2/BCL2/PTEN/BDNF/PENK/CCK/DPP4",13]
["GO:0042445","hormone metabolic process","20/267","221/18866",5.27699708954763e-11,8.44488668849722e-10,3.02483740052005e-10,"TG/REST/ESR1/COMT/CYP2D6/TSPO/HIF1A/PPARGC1A/GNB3/TPO/TTR/NGF/CYP1A2/SRD5A1/ACE/CYP3A4/SHH/LEP/PTPN11/ADH1C",20]
["GO:0051099","positive regulation of binding","18/267","174/18866",5.4708176965357e-11,8.72709033827564e-10,3.12591870402359e-10,"PON1/PAX6/IGF1/GSK3B/EP300/TGFB1/IFNG/STMN1/APOE/MEN1/NGF/PLK2/ACE/CDK5/CTNNB1/BDNF/PRKN/LRRK2",18]
["GO:0150076","neuroinflammatory response","13/267","77/18866",5.60021948356681e-11,8.9050623826271e-10,3.18966574005364e-10,"IGF1/TNFRSF1B/GRN/PTGS2/IFNG/IL1B/IL6/IL18/JUN/MAPT/LRRK2/AGER/TNF",13]
["GO:0071219","cellular response to molecule of bacterial origin","20/267","222/18866",5.72681864209485e-11,9.07746205713638e-10,3.25141683305569e-10,"NOS2/TNFRSF1B/MAPK1/XBP1/TSPO/MAPK3/TGFB1/MAPK8/CCL2/PPARGC1A/IL1A/IL1B/IL6/IL10/AKT1/IL18/NOS3/CXCL8/PRKCE/TNF",20]
["GO:0007405","neuroblast proliferation","12/267","62/18866",5.81347839891596e-11,9.18566381195803e-10,3.29017315115197e-10,"PAX6/FGFR2/FGFR1/HIF1A/VEGFA/TP53/DRD2/SHH/CTNNB1/BDNF/LRRK2/NF1",12]
["GO:0007626","locomotory behavior","19/267","198/18866",5.8858583926878e-11,9.27069115289911e-10,3.3206287262748e-10,"OPRM1/APOE/IDO1/PPP1R1B/SOD1/SLC6A3/DRD2/GDNF/MECP2/ALK/PRKCE/CHD7/PTEN/SNCG/PENK/PRKN/LRRK2/DPP4/MTOR",19]
["GO:0001678","cellular glucose homeostasis","17/267","153/18866",6.08635011918589e-11,9.55633526575319e-10,3.42294235435181e-10,"GCLC/NGFR/PRKACA/SIRT1/SMARCB1/XBP1/HIF1A/PPARGC1A/SRF/PIK3CA/MEN1/RAC1/POLG/PIK3R1/PRKCE/HLA-DRB1/AGER",17]
["GO:0050867","positive regulation of cell activation","27/267","421/18866",6.44751051616257e-11,1.00916677138557e-09,3.61469076619706e-10,"CD38/TAC1/IGF1/GLI2/XBP1/TGFB1/CCL2/IL2/IFNG/PDGFRB/IL1A/PIK3CA/IL1B/RAC1/IL6/IL10/AKT1/PIK3R1/IL18/SHH/FADD/BCL2/LEP/PTPN11/LRRK2/DPP4/AGER",27]
["GO:0006352","DNA-templated transcription, initiation","21/267","249/18866",6.48599479378811e-11,1.01201787516825e-09,3.62490301139671e-10,"CREBBP/NOTCH3/BAX/ESR1/SMARCB1/MAPK3/PPARGC1A/VDR/TBP/SRF/NR3C1/CREB1/ESR2/TP53/NR3C2/CTNNB1/MECP2/AR/PTEN/JUN/MED12",21]
["GO:0010634","positive regulation of epithelial cell migration","18/267","176/18866",6.62349552395585e-11,1.03025274614055e-09,3.69021770624725e-10,"TAC1/GRN/HDAC9/PTGS2/FGFR1/HDAC6/SIRT1/HIF1A/TGFB1/IFNG/VEGFA/PTK2B/AKT1/PLK2/NOS3/PRKCE/JUN/MTOR",18]
["GO:0034504","protein localization to nucleus","22/267","277/18866",7.22733566427393e-11,1.12068593079875e-09,4.01413641503805e-10,"NGFR/PTGS2/GSK3B/MAPK1/TSC2/TGFB1/COL1A1/IFNG/LIF/SYNE1/GLUL/TOR1A/TP53/AKT1/PIK3R1/SHH/CDK5/LEP/F2/LRRK2/NF1/INS",22]
["GO:0045995","regulation of embryonic development","16/267","134/18866",7.56422212668383e-11,1.16929291264806e-09,4.18823965886779e-10,"IGF1/PRKACA/FGFR1/GATA1/SFRP1/IL10/DVL3/SHH/OTX2/CTNNB1/GDNF/AR/FZD2/EHMT1/ADIPOQ/DLL1",16]
["GO:0006809","nitric oxide biosynthetic process","13/267","79/18866",7.84419054652551e-11,1.20882849996302e-09,4.32985046736415e-10,"NOS2/PTGS2/TSPO/IFNG/PTK2B/IL1B/RAC1/IL10/AKT1/NOS3/NQO1/MTOR/TNF",13]
["GO:0022409","positive regulation of cell-cell adhesion","22/267","279/18866",8.30843787451052e-11,1.27643170176711e-09,4.5719954490019e-10,"IGF1/GLI2/XBP1/CCL2/IL2/IFNG/IL1A/PIK3CA/IL1B/RAC1/IL6/IL10/AKT1/PIK3R1/IL18/SHH/FADD/LEP/PTPN11/DPP4/AGER/TNF",22]
["GO:0032368","regulation of lipid transport","16/267","135/18866",8.47369106571787e-11,1.29782636475857e-09,4.64862806608158e-10,"PON1/TAC1/P2RX7/SIRT1/TSPO/OXT/POMC/IL1B/APOE/AKT1/SHH/LEP/PTPN11/ADIPOQ/PRKN/PTCH1",16]
["GO:0006631","fatty acid metabolic process","26/267","396/18866",8.90008415754038e-11,1.35543248380061e-09,4.85496492980116e-10,"PON1/BRCA1/TNFRSF1A/ACSL4/PTGS2/SIRT1/CYP2D6/XBP1/MAPK3/PPARGC1A/CNR1/IL1B/CYP2E1/PER2/GSTM1/CYP1A2/AKT1/CYP3A4/CYP2C19/LEP/LPL/ADIPOQ/CYP2B6/MTOR/GPX1/INS",26]
["GO:0007548","sex differentiation","22/267","280/18866",8.90410283770477e-11,1.35543248380061e-09,4.85496492980116e-10,"ATRX/BAX/ESR1/SIRT1/GATA1/SFRP1/FGF8/VEGFA/PDGFRB/BRCA2/SOD1/SRD5A1/GNRH1/SHH/NOS3/CTNNB1/AR/CHD7/BCL2L1/BCL2/LEP/PTPN11",22]
["GO:0006476","protein deacetylation","14/267","97/18866",9.02834614627561e-11,1.37016815526912e-09,4.90774599344817e-10,"HDAC9/HDAC4/REST/HDAC6/SIRT1/EP300/MAPK8/IFNG/VEGFA/PER2/TP53/MAPT/LRRK2/HDAC2",14]
["GO:0022604","regulation of cell morphogenesis","29/267","499/18866",1.27872393031272e-10,1.93474805577315e-09,6.92999029537896e-10,"NGFR/DLG1/GSK3B/ADNP/OLFM4/CCL2/SRF/VEGFA/PTK2B/APOE/NGF/RAC1/ADAM10/NTRK2/S100B/DVL3/PDLIM5/CDK5/RET/MAP2K1/PTEN/BDNF/F2/CSF1R/PRKN/MAPT/DCC/LRRK2/L1CAM",29]
["GO:0045765","regulation of angiogenesis","26/267","403/18866",1.30497771030597e-10,1.96850565183012e-09,7.05090516714847e-10,"BRCA1/GRN/HDAC9/NGFR/PTGS2/SIRT1/XBP1/HIF1A/SFRP1/VEGFA/IL1A/PTK2B/IL1B/GLUL/IL6/IL10/PLK2/NOS3/CTNNB1/MECP2/CXCL8/PRL/LEP/NF1/DLL1/TNF",26]
["GO:0060425","lung morphogenesis","11/267","52/18866",1.34276940158834e-10,2.01941193437668e-09,7.23324417659667e-10,"FGFR2/MAPK1/MAPK3/FGF8/SRF/LIF/KRAS/SHH/CTNNB1/MAP2K1/TNF",11]
["GO:0009411","response to UV","16/267","140/18866",1.47335944386554e-10,2.20915426523142e-09,7.91287401652458e-10,"CREBBP/PTGS2/BAX/SIRT1/EP300/MAPK8/ATF4/MEN1/REV1/BRCA2/TP53/AKT1/PIK3R1/BCL2/GPX1/MC1R",16]
["GO:0043467","regulation of generation of precursor metabolites and energy","17/267","162/18866",1.51395687182446e-10,2.25923380054211e-09,8.09225173584289e-10,"NOS2/IGF1/HDAC4/GSK3B/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/POMC/PIK3CA/TP53/AKT1/VCP/MTOR/INS",17]
["GO:0045670","regulation of osteoclast differentiation","12/267","67/18866",1.51580877865333e-10,2.25923380054211e-09,8.09225173584289e-10,"GNAS/SFRP1/IFNG/IL17A/CREB1/PIK3R1/FBN1/CTNNB1/FOS/NF1/MTOR/TNF",12]
["GO:0002696","positive regulation of leukocyte activation","26/267","406/18866",1.53360550926766e-10,2.27895604398019e-09,8.16289398573234e-10,"CD38/TAC1/IGF1/GLI2/XBP1/TGFB1/CCL2/IL2/IFNG/IL1A/PIK3CA/IL1B/RAC1/IL6/IL10/AKT1/PIK3R1/IL18/SHH/FADD/BCL2/LEP/PTPN11/LRRK2/DPP4/AGER",26]
["GO:0009267","cellular response to starvation","17/267","163/18866",1.66904609975143e-10,2.47286266351896e-09,8.85743971100323e-10,"COMT/SIRT1/MAPK1/XBP1/MAPK3/SFRP1/MAPK8/ATF4/GLUL/TP53/SRD5A1/ATF3/ALB/BCL2/JUN/LRRK2/MTOR",17]
["GO:0010876","lipid localization","27/267","440/18866",1.73772067356197e-10,2.56699388257246e-09,9.19460424908685e-10,"PON1/TAC1/NOS2/ACSL4/APOB/ABCB1/P2RX7/SIRT1/TSPO/OXT/POMC/IL1B/APOE/CRP/IL6/FTO/AKT1/DRD2/ACE/SHH/LEP/LPL/PTPN11/ADIPOQ/PRKN/PTCH1/TNF",27]
["GO:0046209","nitric oxide metabolic process","13/267","84/18866",1.7466428854091e-10,2.57256281027955e-09,9.21455135013218e-10,"NOS2/PTGS2/TSPO/IFNG/PTK2B/IL1B/RAC1/IL10/AKT1/NOS3/NQO1/MTOR/TNF",13]
["GO:0050679","positive regulation of epithelial cell proliferation","19/267","211/18866",1.7698118154596e-10,2.59902070429111e-09,9.30931973518841e-10,"IGF1/GRN/FGFR2/FGFR1/SIRT1/XBP1/HIF1A/SFRP1/VEGFA/GLUL/IL10/CDH13/AKT1/SHH/CTNNB1/AR/JUN/NF1/MTOR",19]
["GO:0040014","regulation of multicellular organism growth","12/267","68/18866",1.81768309922313e-10,2.66149317138448e-09,9.5330871603028e-10,"IGF1/POU1F1/CREB1/PIK3CA/FTO/SOD1/SLC6A3/DRD2/CHD7/BCL2/PRL/PTCH1",12]
["GO:0072073","kidney epithelium development","16/267","142/18866",1.82632845106987e-10,2.66633273572861e-09,9.55042178629642e-10,"FGFR2/DLG1/FGFR1/SFRP1/FGF8/VEGFA/LIF/SHH/RET/CTNNB1/GDNF/BCL2/BDNF/ADIPOQ/PTCH1/DLL1",16]
["GO:0016571","histone methylation","16/267","143/18866",2.0306396517726e-10,2.92996758848817e-09,1.04947240512326e-09,"CREBBP/BRCA1/ATRX/SIRT1/SMARCB1/KMT2A/DNMT1/PRMT7/MEN1/KDM6A/KMT2D/CTNNB1/MECP2/MTHFR/EHMT1/PAX5",16]
["GO:0035296","regulation of tube diameter","16/267","143/18866",2.0306396517726e-10,2.92996758848817e-09,1.04947240512326e-09,"GCLC/CD38/PTGS2/HTR2A/SOD2/APOE/PER2/CRP/SOD1/AKT1/EDNRA/ACE/NOS3/LEP/GPX1/INS",16]
["GO:0097746","regulation of blood vessel diameter","16/267","143/18866",2.0306396517726e-10,2.92996758848817e-09,1.04947240512326e-09,"GCLC/CD38/PTGS2/HTR2A/SOD2/APOE/PER2/CRP/SOD1/AKT1/EDNRA/ACE/NOS3/LEP/GPX1/INS",16]
["GO:0045844","positive regulation of striated muscle tissue development","13/267","85/18866",2.03624825396634e-10,2.92996758848817e-09,1.04947240512326e-09,"IGF1/ERBB3/FGFR2/FGFR1/MAPK1/TGFB1/CREB1/SHH/CTNNB1/BCL2/ERBB4/DLL1/MTOR",13]
["GO:0048636","positive regulation of muscle organ development","13/267","85/18866",2.03624825396634e-10,2.92996758848817e-09,1.04947240512326e-09,"IGF1/ERBB3/FGFR2/FGFR1/MAPK1/TGFB1/CREB1/SHH/CTNNB1/BCL2/ERBB4/DLL1/MTOR",13]
["GO:1904375","regulation of protein localization to cell periphery","15/267","123/18866",2.21470471981467e-10,3.17759214541225e-09,1.1381679730687e-09,"DLG1/TGFB1/IFNG/ADAM10/AKT1/PIK3R1/SQSTM1/PRKCI/CDK5/AR/PRKCE/BCL2L1/GPC6/TNF/INS",15]
["GO:1903531","negative regulation of secretion by cell","17/267","166/18866",2.22689155060854e-10,3.18592249632907e-09,1.14115178539705e-09,"TNFRSF1B/HDAC9/TNFRSF1A/REST/SFRP1/OPRM1/CNR1/IL1B/LIF/APOE/DRD2/LEP/PTPN11/ADIPOQ/PRKN/NF1/INS",17]
["GO:0035150","regulation of tube size","16/267","144/18866",2.25583360582121e-10,3.21810776967579e-09,1.15268008910984e-09,"GCLC/CD38/PTGS2/HTR2A/SOD2/APOE/PER2/CRP/SOD1/AKT1/EDNRA/ACE/NOS3/LEP/GPX1/INS",16]
["GO:0051101","regulation of DNA binding","15/267","124/18866",2.48791947982132e-10,3.53908318027004e-09,1.26764888175631e-09,"PAX6/IGF1/EP300/GATA1/TGFB1/MAPK8/IFNG/LIF/PER2/NGF/CTNNB1/JUN/PRKN/HDAC2/AGER",15]
["GO:0051353","positive regulation of oxidoreductase activity","11/267","55/18866",2.56197868342255e-10,3.63407942225249e-09,1.30167517438245e-09,"HIF1A/VDR/IFNG/PTK2B/IL1B/APOE/KRAS/AKT1/GDNF/TNF/INS",11]
["GO:0005996","monosaccharide metabolic process","22/267","296/18866",2.59075261077661e-10,3.66448379195683e-09,1.31256558393006e-09,"GCLC/IGF1/GSK3B/SIRT1/EP300/PPARGC1A/GNB3/POMC/PIK3CA/ATF4/PER2/TP53/AKT1/ATF3/INPPL1/PRKCE/LEP/ADIPOQ/PRKN/MTOR/TNF/INS",22]
["GO:0006066","alcohol metabolic process","25/267","385/18866",2.63357381886741e-10,3.71452940045338e-09,1.33049120376323e-09,"PON1/IGF1/POU1F1/FGFR1/REST/APOB/CYP2D6/VDR/IFNG/GNB3/TTR/PTK2B/IL1B/APOE/CYP27A1/CYP1A2/SOD1/LBR/CYP3A4/INPPL1/MECP2/PTEN/LEP/TNF/ADH1C",25]
["GO:0062014","negative regulation of small molecule metabolic process","14/267","105/18866",2.67810101999326e-10,3.7666925050215e-09,1.34917528034649e-09,"BRCA1/HDAC4/REST/SIRT1/EP300/TGFB1/PPARGC1A/CNR1/APOE/TP53/SOD1/AKT1/ADIPOQ/INS",14]
["GO:2001057","reactive nitrogen species metabolic process","13/267","87/18866",2.75026533691856e-10,3.85732438967257e-09,1.38163832271574e-09,"NOS2/PTGS2/TSPO/IFNG/PTK2B/IL1B/RAC1/IL10/AKT1/NOS3/NQO1/MTOR/TNF",13]
["GO:0044344","cellular response to fibroblast growth factor stimulus","16/267","146/18866",2.77675948149768e-10,3.8835742552151e-09,1.3910406484047e-09,"GCLC/NGFR/FGFR2/FGFR3/FGFR1/MAPK1/MAPK3/SFRP1/FGF8/CCL2/COL1A1/FGF17/OTX2/CTNNB1/CXCL8/PTPN11",16]
["GO:0008637","apoptotic mitochondrial changes","15/267","125/18866",2.7917659079472e-10,3.8936556364191e-09,1.39465165469047e-09,"GCLC/IGF1/GSK3B/BAX/MAPK8/SOD2/TP53/AKT1/BCL2L1/BCL2/JUN/ERBB4/PRKN/CCK/GPX1",15]
["GO:0021953","central nervous system neuron differentiation","18/267","192/18866",2.80039481125243e-10,3.8948109450093e-09,1.39506546967245e-09,"PAX6/FGFR2/GLI2/SFRP1/FGF8/NPY/NTRK2/DRD2/SHH/CDK5/CTNNB1/PTEN/LEP/ERBB4/CSF1R/PTCH1/MAPT/DCC",18]
["GO:0051100","negative regulation of binding","17/267","169/18866",2.95297528573067e-10,4.0956126671259e-09,1.4669897691393e-09,"GSK3B/BAX/CYP2D6/ADNP/GATA1/MAPK3/MAPK8/STMN1/PER2/IL10/AKT1/ACE/ATP2A2/JUN/ADIPOQ/LRRK2/HDAC2",17]
["GO:0051251","positive regulation of lymphocyte activation","24/267","357/18866",3.02878783692235e-10,4.18912400824191e-09,1.50048419155302e-09,"CD38/TAC1/IGF1/GLI2/XBP1/TGFB1/CCL2/IL2/IFNG/IL1A/PIK3CA/IL1B/RAC1/IL6/AKT1/PIK3R1/IL18/SHH/FADD/BCL2/LEP/PTPN11/DPP4/AGER",24]
["GO:1905269","positive regulation of chromatin organization","14/267","106/18866",3.0470280292114e-10,4.19366675592412e-09,1.50211133867732e-09,"BRCA1/SIRT1/SMARCB1/MAPK3/PPARGC1A/VEGFA/KMT2A/IL1B/LIF/DNMT1/TP53/CTNNB1/MECP2/LRRK2",14]
["GO:0014072","response to isoquinoline alkaloid","9/267","31/18866",3.05726957571876e-10,4.19366675592412e-09,1.50211133867732e-09,"TAC1/OPRM1/CNR1/PPP1R1B/DRD2/FADD/PRKCE/PENK/MTOR",9]
["GO:0043278","response to morphine","9/267","31/18866",3.05726957571876e-10,4.19366675592412e-09,1.50211133867732e-09,"TAC1/OPRM1/CNR1/PPP1R1B/DRD2/FADD/PRKCE/PENK/MTOR",9]
["GO:0060688","regulation of morphogenesis of a branching structure","11/267","56/18866",3.14863457714575e-10,4.30715957361335e-09,1.5427628396743e-09,"FGFR2/FGFR1/ESR1/SFRP1/VEGFA/SHH/CTNNB1/GDNF/AR/LRRK2/TNF",11]
["GO:0035601","protein deacylation","14/267","107/18866",3.46185459277475e-10,4.72268851959681e-09,1.69159935378899e-09,"HDAC9/HDAC4/REST/HDAC6/SIRT1/EP300/MAPK8/IFNG/VEGFA/PER2/TP53/MAPT/LRRK2/HDAC2",14]
["GO:1900180","regulation of protein localization to nucleus","15/267","127/18866",3.50399207573035e-10,4.76714780221298e-09,1.70752403174125e-09,"NGFR/PTGS2/GSK3B/MAPK1/TGFB1/IFNG/LIF/GLUL/AKT1/PIK3R1/SHH/LEP/F2/NF1/INS",15]
["GO:1902275","regulation of chromatin organization","18/267","195/18866",3.61117488386005e-10,4.89961853128077e-09,1.75497314864938e-09,"BRCA1/ATRX/SIRT1/SMARCB1/MAPK3/MAPK8/PPARGC1A/VEGFA/KMT2A/IL1B/LIF/DNMT1/TP53/CTNNB1/MECP2/MTHFR/LRRK2/PAX5",18]
["GO:0002064","epithelial cell development","19/267","221/18866",3.90952343768192e-10,5.28907815670391e-09,1.8944720057006e-09,"PAX6/TNFRSF1A/FGFR1/GSK3B/ATRX/ESR1/XBP1/HIF1A/VEGFA/IL1B/ATF4/FLNB/SOD1/CTNNB1/AR/ADIPOQ/DLL1/TNF/GPX1",19]
["GO:0014013","regulation of gliogenesis","15/267","128/18866",3.91940500296505e-10,5.28907815670391e-09,1.8944720057006e-09,"TNFRSF1B/TSPO/TGFB1/CREB1/IL1B/LIF/IL6/PRKCI/SHH/CTNNB1/F2/HDAC2/NF1/MTOR/TNF",15]
["GO:0070665","positive regulation of leukocyte proliferation","16/267","150/18866",4.16562530711197e-10,5.60619060873586e-09,2.00805714194445e-09,"CD38/TAC1/IGF1/MAPK1/MAPK3/IL2/IL1A/IL1B/IL6/IL18/SHH/FADD/BCL2/LEP/CSF1R/AGER",16]
["GO:1903351","cellular response to dopamine","13/267","90/18866",4.25349881349973e-10,5.7090644020979e-09,2.04490506059311e-09,"GSK3B/GNAS/MAPK1/HTR2A/MAPK3/OPRM1/ATF4/GNAL/DRD2/ALK/PRKN/LRRK2/HDAC2",13]
["GO:0002763","positive regulation of myeloid leukocyte differentiation","11/267","58/18866",4.69583317398218e-10,6.28586998329572e-09,2.25150855442239e-09,"GNAS/TGFB1/IFNG/IL17A/CREB1/LIF/FADD/FOS/JUN/HLA-DRB1/TNF",11]
["GO:0051052","regulation of DNA metabolic process","24/267","365/18866",4.74541917671935e-10,6.33526148378602e-09,2.26919988214078e-09,"BRCA1/ATRX/BAX/FUS/SIRT1/MAPK1/MAPK3/TGFB1/IL2/PPARGC1A/TIMELESS/PDGFRB/KMT2A/DUSP1/PTK2B/PIK3CA/MEN1/IL6/IL10/TP53/AKT1/CTNNB1/MECP2/ADIPOQ",24]
["GO:1903350","response to dopamine","13/267","91/18866",4.90042873650879e-10,6.52475751503691e-09,2.33707464514482e-09,"GSK3B/GNAS/MAPK1/HTR2A/MAPK3/OPRM1/ATF4/GNAL/DRD2/ALK/PRKN/LRRK2/HDAC2",13]
["GO:0043583","ear development","19/267","224/18866",4.91713443303412e-10,6.52958835748388e-09,2.3388049836856e-09,"COL11A1/FGFR2/GLI2/FGFR1/MAPK1/MAPK3/FGF8/PDGFRB/ADAM10/COL2A1/SOD1/HESX1/SHH/CHD7/BCL2/BDNF/PTPN11/FZD2/DLL1",19]
["GO:0001935","endothelial cell proliferation","18/267","199/18866",5.03203885486445e-10,6.66444827648228e-09,2.3871098741909e-09,"NGFR/DLG1/FGFR1/SIRT1/XBP1/HIF1A/CCL2/VEGFA/APOE/IL10/CDH13/AKT1/PRL/LEP/JUN/NF1/MTOR/TNF",18]
["GO:0050680","negative regulation of epithelial cell proliferation","17/267","175/18866",5.10224646441404e-10,6.7395546552432e-09,2.41401190282357e-09,"PAX6/NGFR/FGFR2/DLG1/SFRP1/TGFB1/CCL2/VDR/APOE/MEN1/BRCA2/AR/PTEN/PRL/PTCH1/NF1/TNF",17]
["GO:0045667","regulation of osteoblast differentiation","15/267","131/18866",5.45180899340143e-10,7.18229084539666e-09,2.57259366193279e-09,"IGF1/FGFR2/HDAC4/PRKACA/REST/GNAS/SFRP1/ATF4/MEN1/IL6/IL6R/CTNNB1/PTCH1/TNF/TWIST2",15]
["GO:0071774","response to fibroblast growth factor","16/267","153/18866",5.59969534819476e-10,7.34610886727181e-09,2.63127092993239e-09,"GCLC/NGFR/FGFR2/FGFR3/FGFR1/MAPK1/MAPK3/SFRP1/FGF8/CCL2/COL1A1/FGF17/OTX2/CTNNB1/CXCL8/PTPN11",16]
["GO:0014002","astrocyte development","10/267","45/18866",5.62029558841945e-10,7.34610886727181e-09,2.63127092993239e-09,"GRN/IFNG/IL1B/KRAS/IL6/MAPT/NF1/DLL1/AGER/TNF",10]
["GO:0035094","response to nicotine","10/267","45/18866",5.62029558841945e-10,7.34610886727181e-09,2.63127092993239e-09,"MAPK1/CREB1/CNR1/PPP1R1B/SLC6A3/DRD2/BCL2/PENK/HDAC2/TNF",10]
["GO:0002526","acute inflammatory response","14/267","111/18866",5.68993594103171e-10,7.39258414862201e-09,2.64791770974286e-09,"TAC1/PTGS2/OPRM1/IL1A/CNR1/IL1B/CRP/IL6/IL6R/F2/SERPINA3/TNF/INS/HP",14]
["GO:0098732","macromolecule deacylation","14/267","111/18866",5.68993594103171e-10,7.39258414862201e-09,2.64791770974286e-09,"HDAC9/HDAC4/REST/HDAC6/SIRT1/EP300/MAPK8/IFNG/VEGFA/PER2/TP53/MAPT/LRRK2/HDAC2",14]
["GO:0043525","positive regulation of neuron apoptotic process","11/267","59/18866",5.7002701726807e-10,7.39258414862201e-09,2.64791770974286e-09,"GRN/HDAC4/BAX/ATF4/TP53/CDK5/CTNNB1/JUN/NQO1/NF1/TNF",11]
["GO:1903798","regulation of production of miRNAs involved in gene silencing by miRNA","8/267","23/18866",5.91338546262828e-10,7.6491019727728e-09,2.73979871857253e-09,"ESR1/TGFB1/MAP2K2/IL6/TP53/MAP2K1/LIN28B/TNF",8]
["GO:0050808","synapse organization","26/267","433/18866",6.14085449622052e-10,7.92281304899976e-09,2.83783810392457e-09,"DLG1/REST/HDAC6/ADNP/OXT/APOE/IL10/ADAM10/NTRK2/DRD2/PDLIM5/CDK5/VCP/CTNNB1/GDNF/MECP2/PTEN/SNCG/BDNF/ERBB4/GPC6/MAPT/LRRK2/L1CAM/TNF/INS",26]
["GO:0019318","hexose metabolic process","20/267","254/18866",6.33659117336919e-10,8.15427828057535e-09,2.9207456330858e-09,"IGF1/GSK3B/SIRT1/EP300/PPARGC1A/GNB3/POMC/PIK3CA/ATF4/PER2/TP53/AKT1/ATF3/INPPL1/LEP/ADIPOQ/PRKN/MTOR/TNF/INS",20]
["GO:0046822","regulation of nucleocytoplasmic transport","14/267","112/18866",6.42142352433758e-10,8.24220248252378e-09,2.95223882231079e-09,"PRKACA/PTGS2/GSK3B/MAPK1/TGFB1/IFNG/IL1B/TP53/PIK3R1/SHH/CDK5/LEP/PTPN11/NF1",14]
["GO:0001836","release of cytochrome c from mitochondria","11/267","60/18866",6.89323168940706e-10,8.82510405774601e-09,3.16102581384685e-09,"IGF1/BAX/SOD2/TP53/AKT1/BCL2L1/BCL2/JUN/PRKN/CCK/GPX1",11]
["GO:0032868","response to insulin","21/267","283/18866",6.91253696668644e-10,8.82718595259984e-09,3.16177151875091e-09,"GCLC/HDAC9/GSK3B/SIRT1/XBP1/TSC2/PIK3CA/IL1B/IL10/AKT1/SRD5A1/PIK3R1/PRKCI/INPPL1/PTEN/LEP/LPL/PTPN11/ADIPOQ/MTOR/INS",21]
["GO:0046683","response to organophosphorus","15/267","134/18866",7.51680799282091e-10,9.5743424255497e-09,3.42939226095669e-09,"PTGS2/P2RX7/OXT/COL1A1/DUSP1/PTK2B/IL1B/LDHA/SOD1/SLC6A3/SRD5A1/FOS/PTEN/ADIPOQ/PENK",15]
["GO:0033619","membrane protein proteolysis","11/267","61/18866",8.3052982299966e-10,1.05517440362272e-08,3.77948351219077e-09,"TNFRSF1B/NGFR/P2RX7/TGFB1/IFNG/IL1B/APOE/IL10/ADAM10/RET/TNF",11]
["GO:1905330","regulation of morphogenesis of an epithelium","17/267","181/18866",8.62386046295053e-10,1.09286637795716e-08,3.91449076317204e-09,"FGFR1/ESR1/SFRP1/VEGFA/LIF/RAC1/DVL3/SHH/CTNNB1/GDNF/AR/PTEN/FZD2/GPC6/MED12/MTOR/TNF",17]
["GO:0042594","response to starvation","18/267","206/18866",8.8243229955241e-10,1.11543910675068e-08,3.99534304314336e-09,"COMT/SIRT1/MAPK1/XBP1/MAPK3/SFRP1/MAPK8/PPARGC1A/ATF4/GLUL/TP53/SRD5A1/ATF3/ALB/BCL2/JUN/LRRK2/MTOR",18]
["GO:0008542","visual learning","10/267","47/18866",8.89824079694469e-10,1.12194233078649e-08,4.01863665975785e-09,"HIF1A/CREB1/PPP1R1B/KRAS/DRD2/CDK5/MECP2/CCK/NF1/MTOR",10]
["GO:0007519","skeletal muscle tissue development","16/267","158/18866",9.0318834657175e-10,1.13307020463134e-08,4.05849510929755e-09,"HDAC9/HDAC4/EP300/TGFB1/FLNB/S100B/ATF3/SHH/CDK5/CTNNB1/FOS/BCL2/PAX5/NF1/DLL1/GPX1",16]
["GO:0050729","positive regulation of inflammatory response","16/267","158/18866",9.0318834657175e-10,1.13307020463134e-08,4.05849510929755e-09,"TAC1/GRN/TNFRSF1A/PTGS2/IL2/IFNG/IL17A/CNR1/IL1B/IDO1/IL6/IL18/LPL/LRRK2/TNF/NEAT1",16]
["GO:0030183","B cell differentiation","15/267","137/18866",1.02772761547631e-09,1.28286099601831e-08,4.59502425972172e-09,"HDAC9/POU1F1/HDAC4/BAX/XBP1/EP300/SFRP1/PTK2B/IL6/IL10/TP53/PIK3R1/BCL2/IFNA1/DLL1",15]
["GO:0071326","cellular response to monosaccharide stimulus","15/267","137/18866",1.02772761547631e-09,1.28286099601831e-08,4.59502425972172e-09,"GCLC/PRKACA/SMARCB1/XBP1/HIF1A/PPARGC1A/SRF/PIK3CA/MEN1/RAC1/POLG/PRKCE/LEP/HLA-DRB1/AGER",15]
["GO:0010827","regulation of glucose transmembrane transport","12/267","79/18866",1.11355503337346e-09,1.38307967204818e-08,4.95399319639042e-09,"IGF1/IL1B/AKT1/PIK3R1/EDNRA/BRAF/PRKCI/LEP/PTPN11/ADIPOQ/TNF/INS",12]
["GO:0071260","cellular response to mechanical stimulus","12/267","79/18866",1.11355503337346e-09,1.38307967204818e-08,4.95399319639042e-09,"GCLC/TNFRSF1A/HDAC4/PTGS2/MAPK3/MAPK8/COL1A1/IL1B/RAC1/AKT1/FADD/PTPN11",12]
["GO:0060560","developmental growth involved in morphogenesis","19/267","236/18866",1.18684494339426e-09,1.47045081944604e-08,5.26694412649038e-09,"FGFR2/GSK3B/ESR1/HDAC6/ADNP/SFRP1/SRF/VEGFA/APOE/NGF/SHH/CDK5/CTNNB1/BDNF/MED12/PRKN/MAPT/DCC/L1CAM",19]
["GO:0001657","ureteric bud development","13/267","98/18866",1.25783515941003e-09,1.5507088767739e-08,5.55441698723234e-09,"FGFR2/DLG1/FGFR1/SFRP1/FGF8/VEGFA/SHH/RET/CTNNB1/GDNF/BCL2/BDNF/PTCH1",13]
["GO:0030316","osteoclast differentiation","13/267","98/18866",1.25783515941003e-09,1.5507088767739e-08,5.55441698723234e-09,"GNAS/SFRP1/IFNG/IL17A/CREB1/PIK3R1/FBN1/CTNNB1/FOS/CSF1R/NF1/MTOR/TNF",13]
["GO:0070920","regulation of production of small RNA involved in gene silencing by RNA","8/267","25/18866",1.27282166745897e-09,1.56531984867553e-08,5.60675139489966e-09,"ESR1/TGFB1/MAP2K2/IL6/TP53/MAP2K1/LIN28B/TNF",8]
["GO:1900182","positive regulation of protein localization to nucleus","12/267","80/18866",1.29374267707948e-09,1.58713935790119e-08,5.68490575031173e-09,"NGFR/PTGS2/MAPK1/TGFB1/IFNG/LIF/AKT1/PIK3R1/SHH/LEP/F2/INS",12]
["GO:0001654","eye development","24/267","384/18866",1.31336471344301e-09,1.60494473765501e-08,5.74868206916179e-09,"PAX6/DLG1/BAX/HIF1A/SRF/VEGFA/PDGFRB/MFN2/ATF4/SLC6A3/NTRK2/DRD2/PRKCI/SHH/RET/FBN1/CTNNB1/CHD7/BCL2/BDNF/JUN/HDAC2/NF1/DLL1",24]
["GO:0051147","regulation of muscle cell differentiation","17/267","186/18866",1.31468535489865e-09,1.60494473765501e-08,5.74868206916179e-09,"IGF1/HDAC9/FGFR2/HDAC4/SIRT1/XBP1/TGFB1/SOD2/SRF/DNMT1/SHH/CTNNB1/MECP2/BCL2/BDNF/DLL1/MTOR",17]
["GO:1901099","negative regulation of signal transduction in absence of ligand","9/267","36/18866",1.34208039849266e-09,1.63041543301067e-08,5.83991445009355e-09,"GATA1/IL1A/IL1B/COL2A1/AKT1/GDNF/BCL2L1/BCL2/TNF",9]
["GO:2001240","negative regulation of extrinsic apoptotic signaling pathway in absence of ligand","9/267","36/18866",1.34208039849266e-09,1.63041543301067e-08,5.83991445009355e-09,"GATA1/IL1A/IL1B/COL2A1/AKT1/GDNF/BCL2L1/BCL2/TNF",9]
["GO:0031349","positive regulation of defense response","24/267","385/18866",1.38317129504232e-09,1.67625589226852e-08,6.0041084064305e-09,"CREBBP/TAC1/GRN/TNFRSF1A/PRKACA/PTGS2/EP300/MAPK3/IL2/IFNG/IL17A/CNR1/IL1B/IDO1/KRAS/IL6/IL18/FADD/LPL/PENK/CCK/LRRK2/TNF/NEAT1",24]
["GO:0060135","maternal process involved in female pregnancy","11/267","64/18866",1.42277819764944e-09,1.71365283403841e-08,6.13805889304239e-09,"PTGS2/ESR1/MAPK1/MAPK3/VDR/CNR1/LIF/MEN1/AKT1/AR/MTOR",11]
["GO:0043255","regulation of carbohydrate biosynthetic process","13/267","99/18866",1.42988972770948e-09,1.71365283403841e-08,6.13805889304239e-09,"IGF1/POU1F1/GSK3B/SIRT1/EP300/TGFB1/PPARGC1A/PTK2B/AKT1/LEP/ADIPOQ/MTOR/INS",13]
["GO:0072163","mesonephric epithelium development","13/267","99/18866",1.42988972770948e-09,1.71365283403841e-08,6.13805889304239e-09,"FGFR2/DLG1/FGFR1/SFRP1/FGF8/VEGFA/SHH/RET/CTNNB1/GDNF/BCL2/BDNF/PTCH1",13]
["GO:0072164","mesonephric tubule development","13/267","99/18866",1.42988972770948e-09,1.71365283403841e-08,6.13805889304239e-09,"FGFR2/DLG1/FGFR1/SFRP1/FGF8/VEGFA/SHH/RET/CTNNB1/GDNF/BCL2/BDNF/PTCH1",13]
["GO:0021915","neural tube development","16/267","163/18866",1.43119012976971e-09,1.71365283403841e-08,6.13805889304239e-09,"PAX6/PRKACA/GLI2/HIF1A/TSC2/SFRP1/TGFB1/FGF8/KDM6A/DVL3/SHH/MTHFR/FZD2/MED12/PTCH1/NF1",16]
["GO:0046660","female sex differentiation","14/267","119/18866",1.44708881718027e-09,1.72854413018686e-08,6.19139738199264e-09,"BAX/ESR1/SIRT1/SFRP1/VEGFA/BRCA2/SOD1/SRD5A1/GNRH1/NOS3/CHD7/BCL2L1/BCL2/LEP",14]
["GO:0051146","striated muscle cell differentiation","21/267","295/18866",1.46706505051586e-09,1.74822334062665e-08,6.26188549384862e-09,"IGF1/HDAC9/HDAC4/XBP1/TGFB1/PRKAR1A/SRF/VEGFA/PDGFRB/KDM6B/KRAS/AKT1/PDLIM5/SHH/BCL2/BDNF/NEB/DLL1/MTOR/DMD/GPX1",21]
["GO:0031960","response to corticosteroid","16/267","164/18866",1.5660353643758e-09,1.86171775579247e-08,6.6684062257506e-09,"PTGS2/REST/OXT/COL1A1/NR3C1/DUSP1/KRAS/IL6/IL10/SRD5A1/GNRH1/S100B/FOS/BCL2/ADIPOQ/TNF",16]
["GO:0150063","visual system development","24/267","388/18866",1.61398676416659e-09,1.91416530011492e-08,6.85626581402436e-09,"PAX6/DLG1/BAX/HIF1A/SRF/VEGFA/PDGFRB/MFN2/ATF4/SLC6A3/NTRK2/DRD2/PRKCI/SHH/RET/FBN1/CTNNB1/CHD7/BCL2/BDNF/JUN/HDAC2/NF1/DLL1",24]
["GO:0006367","transcription initiation from RNA polymerase II promoter","17/267","189/18866",1.68216792788534e-09,1.98559443591762e-08,7.11211474300658e-09,"CREBBP/NOTCH3/BAX/ESR1/PPARGC1A/VDR/TBP/SRF/NR3C1/CREB1/ESR2/TP53/NR3C2/MECP2/AR/PTEN/MED12",17]
["GO:0043534","blood vessel endothelial cell migration","17/267","189/18866",1.68216792788534e-09,1.98559443591762e-08,7.11211474300658e-09,"HDAC9/PTGS2/FGFR1/SIRT1/HIF1A/TGFB1/SRF/VEGFA/PTK2B/APOE/AKT1/PLK2/NOS3/MECP2/NF1/TNF/GPX1",17]
["GO:0048645","animal organ formation","11/267","65/18866",1.69133787245921e-09,1.98851959819353e-08,7.12259225511674e-09,"FGFR2/GLI2/FGFR1/MAPK1/MAPK3/FGF8/SHH/CTNNB1/GDNF/MAP2K1/AR",11]
["GO:0014009","glial cell proliferation","10/267","50/18866",1.7005765440189e-09,1.98851959819353e-08,7.12259225511674e-09,"TSPO/CREB1/PTK2B/IL1B/IL6/PRKCI/PENK/CSF1R/MTOR/TNF",10]
["GO:0045981","positive regulation of nucleotide metabolic process","10/267","50/18866",1.7005765440189e-09,1.98851959819353e-08,7.12259225511674e-09,"NOS2/IGF1/P2RX7/HIF1A/HTR2A/PPARGC1A/IFNG/NOS3/VCP/INS",10]
["GO:1900544","positive regulation of purine nucleotide metabolic process","10/267","50/18866",1.7005765440189e-09,1.98851959819353e-08,7.12259225511674e-09,"NOS2/IGF1/P2RX7/HIF1A/HTR2A/PPARGC1A/IFNG/NOS3/VCP/INS",10]
["GO:0010906","regulation of glucose metabolic process","14/267","121/18866",1.80649902096248e-09,2.10744149805272e-08,7.54855345945709e-09,"IGF1/GSK3B/SIRT1/EP300/PPARGC1A/GNB3/POMC/TP53/AKT1/LEP/ADIPOQ/PRKN/MTOR/INS",14]
["GO:0045639","positive regulation of myeloid cell differentiation","13/267","101/18866",1.83952868170774e-09,2.14097126055169e-08,7.66865226406932e-09,"GNAS/HIF1A/GATA1/TGFB1/IFNG/IL17A/CREB1/LIF/FADD/FOS/JUN/HLA-DRB1/TNF",13]
["GO:0072006","nephron development","15/267","143/18866",1.87620142615031e-09,2.17857528389965e-08,7.80334448722002e-09,"NOTCH3/DLG1/FGF8/VEGFA/PDGFRB/LIF/IL6R/SHH/RET/CTNNB1/GDNF/BCL2/ADIPOQ/PTCH1/DLL1",15]
["GO:0048145","regulation of fibroblast proliferation","12/267","83/18866",2.00302329097519e-09,2.31666522369114e-08,8.29796286390684e-09,"IGF1/NGFR/BAX/ESR1/SFRP1/PDGFRB/CREB1/TP53/CTNNB1/PAWR/JUN/NF1",12]
["GO:0046824","positive regulation of nucleocytoplasmic transport","11/267","66/18866",2.00440492015737e-09,2.31666522369114e-08,8.29796286390684e-09,"PRKACA/PTGS2/GSK3B/MAPK1/TGFB1/IFNG/IL1B/TP53/PIK3R1/SHH/LEP",11]
["GO:0050921","positive regulation of chemotaxis","15/267","144/18866",2.06813375935591e-09,2.38480181534967e-08,8.54201837157092e-09,"FGFR1/MAPK1/MAPK3/TGFB1/VEGFA/PDGFRB/PTK2B/RAC1/IL6/ADAM10/CDH13/IL6R/CXCL8/CSF1R/AGER",15]
["GO:0060996","dendritic spine development","13/267","102/18866",2.08189693559911e-09,2.38963480447042e-08,8.55932944605658e-09,"ARID1B/ACSL4/HDAC6/IL2/APOE/ADAM10/PLK2/PDLIM5/CDK5/PTEN/LRRK2/HDAC2/MTOR",13]
["GO:1903076","regulation of protein localization to plasma membrane","13/267","102/18866",2.08189693559911e-09,2.38963480447042e-08,8.55932944605658e-09,"DLG1/TGFB1/IFNG/AKT1/PIK3R1/SQSTM1/PRKCI/CDK5/AR/PRKCE/BCL2L1/TNF/INS",13]
["GO:0048880","sensory system development","24/267","394/18866",2.18759980716886e-09,2.50520317366838e-08,8.9732787841137e-09,"PAX6/DLG1/BAX/HIF1A/SRF/VEGFA/PDGFRB/MFN2/ATF4/SLC6A3/NTRK2/DRD2/PRKCI/SHH/RET/FBN1/CTNNB1/CHD7/BCL2/BDNF/JUN/HDAC2/NF1/DLL1",24]
["GO:0060538","skeletal muscle organ development","16/267","168/18866",2.23053966961575e-09,2.54853193830467e-08,9.12847621023041e-09,"HDAC9/HDAC4/EP300/TGFB1/FLNB/S100B/ATF3/SHH/CDK5/CTNNB1/FOS/BCL2/PAX5/NF1/DLL1/GPX1",16]
["GO:0071322","cellular response to carbohydrate stimulus","15/267","145/18866",2.27787408459249e-09,2.59667244392016e-08,9.30090860303445e-09,"GCLC/PRKACA/SMARCB1/XBP1/HIF1A/PPARGC1A/SRF/PIK3CA/MEN1/RAC1/POLG/PRKCE/LEP/HLA-DRB1/AGER",15]
["GO:0048144","fibroblast proliferation","12/267","84/18866",2.30774979138088e-09,2.62473683561839e-08,9.40143123260069e-09,"IGF1/NGFR/BAX/ESR1/SFRP1/PDGFRB/CREB1/TP53/CTNNB1/PAWR/JUN/NF1",12]
["GO:0001823","mesonephros development","13/267","103/18866",2.35286268011697e-09,2.66996440041455e-08,9.56342988880079e-09,"FGFR2/DLG1/FGFR1/SFRP1/FGF8/VEGFA/SHH/RET/CTNNB1/GDNF/BCL2/BDNF/PTCH1",13]
["GO:0016358","dendrite development","19/267","247/18866",2.53980908102206e-09,2.87557068969232e-08,1.02998821545685e-08,"ARID1B/ACSL4/GSK3B/HDAC6/IL2/APOE/ADAM10/RERE/PLK2/PDLIM5/CDK5/MECP2/ALK/PTEN/BDNF/DCC/LRRK2/HDAC2/MTOR",19]
["GO:1902175","regulation of oxidative stress-induced intrinsic apoptotic signaling pathway","8/267","27/18866",2.54935316082594e-09,2.87984622896016e-08,1.0315196523561e-08,"SIRT1/HIF1A/SOD2/SOD1/AKT1/PRKN/GPX1/INS",8]
["GO:0032635","interleukin-6 production","16/267","170/18866",2.65202688610936e-09,2.98414218552555e-08,1.06887696948526e-08,"NOS2/P2RX7/XBP1/IFNG/IL17A/IL1A/IL1B/IL6/IL10/IL18/IL6R/LEP/LPL/PTPN11/AGER/TNF",16]
["GO:0110110","positive regulation of animal organ morphogenesis","12/267","85/18866",2.6536333474331e-09,2.98414218552555e-08,1.06887696948526e-08,"NGFR/FGFR2/FGFR1/BAX/XBP1/FGF8/VDR/VEGFA/LIF/CTNNB1/GDNF/AR",12]
["GO:0001838","embryonic epithelial tube formation","14/267","125/18866",2.779718114857e-09,3.11890619044517e-08,1.11714750494194e-08,"PRKACA/HIF1A/TSC2/SFRP1/TGFB1/KDM6A/DVL3/RET/CTNNB1/GDNF/MTHFR/FZD2/MED12/PTCH1",14]
["GO:0003012","muscle system process","26/267","467/18866",3.02747665427857e-09,3.3892804786576e-08,1.21399170064179e-08,"CD38/IGF1/TNFRSF1B/TNFRSF1A/HDAC4/PRKACA/PTGS2/DLG1/OXT/HTR2A/PPARGC1A/SRF/PIK3CA/IL1B/SOD1/DRD2/EDNRA/PDLIM5/NOS3/GDNF/ATP2A2/LEP/NEB/HDAC2/MTOR/DMD",26]
["GO:0009791","post-embryonic development","12/267","86/18866",3.0455376832922e-09,3.39770341266031e-08,1.21700867490484e-08,"FGFR2/APOB/ATRX/BAX/GNAS/VEGFA/CYP1A2/INPPL1/FBN1/MECP2/BCL2/MTOR",12]
["GO:0045165","cell fate commitment","20/267","278/18866",3.04861031218069e-09,3.39770341266031e-08,1.21700867490484e-08,"PAX6/POU1F1/FGFR2/GLI2/NOTCH3/FGFR1/GATA1/SFRP1/FGF8/KDM6B/IL6/TP53/SHH/CTNNB1/AR/BCL2/ERBB4/PTCH1/DLL1/MTOR",20]
["GO:0007632","visual behavior","10/267","53/18866",3.10985421517452e-09,3.4582410014179e-08,1.23869237172231e-08,"HIF1A/CREB1/PPP1R1B/KRAS/DRD2/CDK5/MECP2/CCK/NF1/MTOR",10]
["GO:0008406","gonad development","18/267","223/18866",3.1506752186857e-09,3.49584919264394e-08,1.25216308691158e-08,"ATRX/BAX/ESR1/SIRT1/GATA1/SFRP1/FGF8/VEGFA/PDGFRB/BRCA2/SOD1/SRD5A1/GNRH1/NOS3/AR/BCL2L1/BCL2/LEP",18]
["GO:0021543","pallium development","16/267","173/18866",3.42262718781605e-09,3.78917462278615e-08,1.35722805277149e-08,"PAX6/GSK3B/BAX/HIF1A/FGF8/SRF/NPY/KDM6B/SRD5A1/NTRK2/CDK5/CTNNB1/ALK/PTEN/PAX5/NF1",16]
["GO:0010575","positive regulation of vascular endothelial growth factor production","8/267","28/18866",3.52561321616154e-09,3.89455459918021e-08,1.39497365026978e-08,"BRCA1/PTGS2/HIF1A/TGFB1/IL1A/IL1B/ATF4/IL6",8]
["GO:0010769","regulation of cell morphogenesis involved in differentiation","21/267","310/18866",3.56708879194876e-09,3.93167203933779e-08,1.40826858545857e-08,"NGFR/GSK3B/ADNP/OLFM4/SRF/VEGFA/APOE/NGF/RAC1/ADAM10/NTRK2/PDLIM5/CDK5/RET/MAP2K1/PTEN/BDNF/MAPT/DCC/LRRK2/L1CAM",21]
["GO:0018205","peptidyl-lysine modification","24/267","405/18866",3.76244447141459e-09,4.13786018629362e-08,1.48212222511787e-08,"CREBBP/BRCA1/HDAC9/HDAC4/ATRX/HDAC6/SIRT1/SMARCB1/EP300/MAPK3/PPARGC1A/KMT2A/IL1B/LIF/DNMT1/MEN1/BRCA2/KDM6A/KMT2D/CTNNB1/MECP2/EHMT1/PAX5/HDAC2",24]
["GO:0072089","stem cell proliferation","14/267","128/18866",3.80000301928346e-09,4.16998133522689e-08,1.49362756038464e-08,"PAX6/FGFR2/FGFR1/ABCB1/HIF1A/VEGFA/TP53/DRD2/ACE/SHH/CTNNB1/BDNF/LRRK2/NF1",14]
["GO:0032869","cellular response to insulin stimulus","18/267","226/18866",3.89581959154555e-09,4.26575158346205e-08,1.52793109095935e-08,"GCLC/HDAC9/GSK3B/SIRT1/XBP1/TSC2/PIK3CA/IL1B/AKT1/SRD5A1/PIK3R1/PRKCI/PTEN/LEP/LPL/PTPN11/ADIPOQ/INS",18]
["GO:0032755","positive regulation of interleukin-6 production","12/267","88/18866",3.98936991664542e-09,4.34534006637877e-08,1.55643854507416e-08,"P2RX7/XBP1/IFNG/IL17A/IL1A/IL1B/IL6/IL6R/LPL/PTPN11/AGER/TNF",12]
["GO:0046889","positive regulation of lipid biosynthetic process","12/267","88/18866",3.98936991664542e-09,4.34534006637877e-08,1.55643854507416e-08,"TNFRSF1A/PTGS2/HTR2A/PPARGC1A/IFNG/CREB1/IL1B/APOE/AKT1/MTOR/TNF/INS",12]
["GO:0051054","positive regulation of DNA metabolic process","17/267","200/18866",3.99461464143372e-09,4.34534006637877e-08,1.55643854507416e-08,"BRCA1/ATRX/BAX/FUS/SIRT1/MAPK1/MAPK3/TGFB1/IL2/PPARGC1A/TIMELESS/PDGFRB/PTK2B/IL6/AKT1/CTNNB1/MECP2",17]
["GO:0007596","blood coagulation","22/267","343/18866",4.10174570547327e-09,4.45217745813653e-08,1.59470616787164e-08,"PRKACA/GNAS/P2RX7/MAPK1/GATA1/MAPK3/COL1A1/PRKAR1A/SRF/MFN2/PIK3CA/APOE/RAC1/IL6/PIK3R1/SHH/NOS3/PRKCE/PTPN11/F2/HDAC2/IFNA1",22]
["GO:0071887","leukocyte apoptotic process","13/267","108/18866",4.25093397523349e-09,4.60410267642967e-08,1.64912360404651e-08,"BAX/P2RX7/SIRT1/HIF1A/IL2/IDO1/IL6/IL10/TP53/AKT1/CDKN2A/FADD/PTEN",13]
["GO:0043270","positive regulation of ion transport","20/267","284/18866",4.39820417639761e-09,4.75329728414572e-08,1.70256297464104e-08,"DLG1/ABCB1/BAX/P2RX7/TSPO/OXT/CCL2/IFNG/PDGFRB/IL1B/ATF4/APOE/AKT1/DRD2/CDK5/GDNF/LEP/F2/CCK/DMD",20]
["GO:1902176","negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway","7/267","19/18866",4.58135397538064e-09,4.94054004299688e-08,1.76963064775985e-08,"SIRT1/HIF1A/SOD2/AKT1/PRKN/GPX1/INS",7]
["GO:0045137","development of primary sexual characteristics","18/267","229/18866",4.80069295430255e-09,5.15480858512529e-08,1.84637856918167e-08,"ATRX/BAX/ESR1/SIRT1/GATA1/SFRP1/FGF8/VEGFA/PDGFRB/BRCA2/SOD1/SRD5A1/GNRH1/NOS3/AR/BCL2L1/BCL2/LEP",18]
["GO:0050920","regulation of chemotaxis","18/267","229/18866",4.80069295430255e-09,5.15480858512529e-08,1.84637856918167e-08,"FGFR1/MAPK1/MAPK3/TGFB1/CCL2/VEGFA/PDGFRB/DUSP1/PTK2B/RAC1/IL6/ADAM10/CDH13/IL6R/CXCL8/CSF1R/DPP4/AGER",18]
["GO:0046887","positive regulation of hormone secretion","14/267","131/18866",5.15048092814311e-09,5.51853031635591e-08,1.97665848134519e-08,"CD38/TAC1/ACSL4/FGFR1/HIF1A/CREB1/GLUL/RAC1/DRD2/PRKCE/LEP/PTPN11/HLA-DRB1/INS",14]
["GO:0070542","response to fatty acid","12/267","90/18866",5.18878369876907e-09,5.54766531219571e-08,1.98709421936406e-08,"PON1/PTGS2/APOB/OXT/SFRP1/PPARGC1A/CREB1/AKT1/GNRH1/PRKCE/LPL/ADIPOQ",12]
["GO:0003007","heart morphogenesis","19/267","258/18866",5.21830319851219e-09,5.56730510046397e-08,1.99412891009272e-08,"COL11A1/FGFR2/HIF1A/TGFB1/FGF8/SRF/VEGFA/COL2A1/TP53/KDM6A/SHH/NOS3/CTNNB1/CHD7/JUN/FZD2/PTCH1/DLL1/MTOR",19]
["GO:0061351","neural precursor cell proliferation","15/267","154/18866",5.25077922574739e-09,5.59000867252808e-08,2.00226100427445e-08,"PAX6/FGFR2/GLI2/FGFR1/HIF1A/FGF8/VEGFA/TP53/RERE/DRD2/SHH/CTNNB1/BDNF/LRRK2/NF1",15]
["GO:0007599","hemostasis","22/267","348/18866",5.34881232177572e-09,5.68225955800557e-08,2.03530394954019e-08,"PRKACA/GNAS/P2RX7/MAPK1/GATA1/MAPK3/COL1A1/PRKAR1A/SRF/MFN2/PIK3CA/APOE/RAC1/IL6/PIK3R1/SHH/NOS3/PRKCE/PTPN11/F2/HDAC2/IFNA1",22]
["GO:0050817","coagulation","22/267","349/18866",5.63716695470637e-09,5.97587571228214e-08,2.14047304861909e-08,"PRKACA/GNAS/P2RX7/MAPK1/GATA1/MAPK3/COL1A1/PRKAR1A/SRF/MFN2/PIK3CA/APOE/RAC1/IL6/PIK3R1/SHH/NOS3/PRKCE/PTPN11/F2/HDAC2/IFNA1",22]
["GO:1904950","negative regulation of establishment of protein localization","15/267","155/18866",5.74056296068157e-09,6.07259128446676e-08,2.17511518068644e-08,"HDAC9/REST/SFRP1/OPRM1/IL1B/APOE/DRD2/CDK5/PTPN11/ADIPOQ/PRKN/MAPT/LRRK2/NF1/INS",15]
["GO:0021983","pituitary gland development","9/267","42/18866",5.90216041759053e-09,6.2044767992169e-08,2.22235468221184e-08,"PAX6/POU1F1/GLI2/FGF8/CREB1/SLC6A3/SRD5A1/DRD2/HESX1",9]
["GO:0001656","metanephros development","12/267","91/18866",5.90251648233132e-09,6.2044767992169e-08,2.22235468221184e-08,"FGF8/PDGFRB/LIF/SHH/RET/FBN1/CTNNB1/GDNF/BCL2/ADIPOQ/PTCH1/NF1",12]
["GO:0051952","regulation of amine transport","12/267","91/18866",5.90251648233132e-09,6.2044767992169e-08,2.22235468221184e-08,"P2RX7/OXT/HTR2A/CNR1/PER2/TOR1A/DRD2/GDNF/SNCG/LEP/PRKN/CCK",12]
["GO:0034612","response to tumor necrosis factor","21/267","320/18866",6.26197414036771e-09,6.56849514345714e-08,2.35274083690507e-08,"BRCA1/TNFRSF1B/TNFRSF1A/HDAC4/PTGS2/APOB/SIRT1/MAPK1/MAPK3/SFRP1/CCL2/COL1A1/PPARGC1A/PTK2B/ADAM10/TP53/AKT1/CXCL8/ADIPOQ/PRKN/TNF",21]
["GO:0032535","regulation of cellular component size","23/267","383/18866",6.28422421698372e-09,6.57801499274628e-08,2.35615071050543e-08,"DLG1/GSK3B/P2RX7/ADNP/GNB3/SRF/VEGFA/CREB1/PTK2B/APOE/NGF/RAC1/AKT1/CDK5/RET/PRKCE/PTEN/BDNF/NEB/MAPT/DCC/MTOR/L1CAM",23]
["GO:0042368","vitamin D biosynthetic process","6/267","12/18866",6.53672315189333e-09,6.82800391159067e-08,2.44569315901052e-08,"VDR/IFNG/IL1B/CYP27A1/CYP3A4/TNF",6]
["GO:0071333","cellular response to glucose stimulus","14/267","134/18866",6.92420694637789e-09,7.21765454765444e-08,2.58526043333612e-08,"GCLC/PRKACA/SMARCB1/XBP1/HIF1A/PPARGC1A/SRF/PIK3CA/MEN1/RAC1/POLG/PRKCE/HLA-DRB1/AGER",14]
["GO:0060965","negative regulation of gene silencing by miRNA","7/267","20/18866",6.96336484024716e-09,7.24335013486544e-08,2.59446422446928e-08,"ESR1/TGFB1/IL6/TP53/LIN28B/TNF/NEAT1",7]
["GO:0021536","diencephalon development","11/267","74/18866",7.05839411231877e-09,7.32693592573964e-08,2.6244034570149e-08,"PAX6/POU1F1/GLI2/BAX/FGF8/CREB1/SLC6A3/SRD5A1/DRD2/HESX1/SHH",11]
["GO:2001252","positive regulation of chromosome organization","16/267","182/18866",7.13333011085778e-09,7.38936042396533e-08,2.64676301776531e-08,"BRCA1/ATRX/SIRT1/SMARCB1/MAPK1/MAPK3/PPARGC1A/VEGFA/KMT2A/IL1B/LIF/DNMT1/TP53/CTNNB1/MECP2/LRRK2",16]
["GO:0001505","regulation of neurotransmitter levels","18/267","235/18866",7.21777873446251e-09,7.43059159199409e-08,2.66153143132975e-08,"GSK3B/P2RX7/COMT/HTR2A/CNR1/PER2/GLUL/TOR1A/SLC6A3/DRD2/CDK5/GDNF/SNCG/ATP2A2/PRKN/LRRK2/MAOA/NF1",18]
["GO:0071695","anatomical structure maturation","18/267","235/18866",7.21777873446251e-09,7.43059159199409e-08,2.66153143132975e-08,"IGF1/FGFR3/PRKACA/FGFR1/XBP1/HIF1A/VEGFA/PTK2B/BRCA2/RERE/RET/CTNNB1/MECP2/BCL2/LEP/LRRK2/NF1/MTOR",18]
["GO:1904018","positive regulation of vasculature development","18/267","235/18866",7.21777873446251e-09,7.43059159199409e-08,2.66153143132975e-08,"BRCA1/GRN/HDAC9/PTGS2/SIRT1/XBP1/HIF1A/SOD2/VEGFA/IL1A/PTK2B/IL1B/IL10/PLK2/IL6R/NOS3/CXCL8/DLL1",18]
["GO:0008631","intrinsic apoptotic signaling pathway in response to oxidative stress","9/267","43/18866",7.37283013630903e-09,7.5524759734894e-08,2.70518867023485e-08,"SIRT1/HIF1A/SOD2/SOD1/AKT1/BCL2/PRKN/GPX1/INS",9]
["GO:0150077","regulation of neuroinflammatory response","9/267","43/18866",7.37283013630903e-09,7.5524759734894e-08,2.70518867023485e-08,"IGF1/TNFRSF1B/GRN/PTGS2/IL1B/IL6/IL18/LRRK2/TNF",9]
["GO:0009895","negative regulation of catabolic process","21/267","323/18866",7.38155072113525e-09,7.5524759734894e-08,2.70518867023485e-08,"NOS2/HDAC4/FUS/TSPO/TSC2/PPARGC1A/CNR1/PIK3CA/IL1B/IL10/TP53/AKT1/SHH/GDNF/BCL2/LEP/LRRK2/MTOR/TNF/INS/HP",21]
["GO:0033157","regulation of intracellular protein transport","19/267","264/18866",7.60698691501211e-09,7.76721588275163e-08,2.78210542860953e-08,"PRKACA/PTGS2/GSK3B/MAPK1/TGFB1/MAPK8/IFNG/IL1B/TP53/PIK3R1/SHH/CDK5/BCL2/LEP/PTPN11/ADIPOQ/PRKN/LRRK2/NF1",19]
["GO:2001235","positive regulation of apoptotic signaling pathway","16/267","183/18866",7.71879689973123e-09,7.86529651435878e-08,2.81723650540137e-08,"NGFR/GSK3B/BAX/SIRT1/SFRP1/MAPK8/TP53/SOD1/ATF3/RET/FADD/BCL2L1/BCL2/PTEN/NF1/TNF",16]
["GO:0032602","chemokine production","11/267","75/18866",8.16889783395904e-09,8.29010302539787e-08,2.96939611037578e-08,"HIF1A/IL17A/IL1B/IL6/IL10/IL18/IL6R/LPL/ADIPOQ/AGER/TNF",11]
["GO:0043627","response to estrogen","11/267","75/18866",8.16889783395904e-09,8.29010302539787e-08,2.96939611037578e-08,"BRCA1/ESR1/COMT/MAPK1/EP300/SFRP1/PDGFRB/LDHA/SRD5A1/KMT2D/AR",11]
["GO:0048588","developmental cell growth","18/267","237/18866",8.24519548611214e-09,8.35056005317605e-08,2.99105095140483e-08,"IGF1/GSK3B/HDAC6/ADNP/SRF/VEGFA/APOE/NGF/PDLIM5/CDK5/KMT2D/CTNNB1/BDNF/PRKN/MAPT/DCC/MTOR/L1CAM",18]
["GO:0001936","regulation of endothelial cell proliferation","16/267","184/18866",8.34796967234675e-09,8.40351059960228e-08,3.010017078378e-08,"NGFR/FGFR1/SIRT1/HIF1A/CCL2/VEGFA/APOE/IL10/CDH13/AKT1/PRL/LEP/JUN/NF1/MTOR/TNF",16]
["GO:0006479","protein methylation","16/267","184/18866",8.34796967234675e-09,8.40351059960228e-08,3.010017078378e-08,"CREBBP/BRCA1/ATRX/SIRT1/SMARCB1/KMT2A/DNMT1/PRMT7/MEN1/KDM6A/KMT2D/CTNNB1/MECP2/MTHFR/EHMT1/PAX5",16]
["GO:0008213","protein alkylation","16/267","184/18866",8.34796967234675e-09,8.40351059960228e-08,3.010017078378e-08,"CREBBP/BRCA1/ATRX/SIRT1/SMARCB1/KMT2A/DNMT1/PRMT7/MEN1/KDM6A/KMT2D/CTNNB1/MECP2/MTHFR/EHMT1/PAX5",16]
["GO:0071331","cellular response to hexose stimulus","14/267","136/18866",8.39781115976232e-09,8.43667426975719e-08,3.02189582980751e-08,"GCLC/PRKACA/SMARCB1/XBP1/HIF1A/PPARGC1A/SRF/PIK3CA/MEN1/RAC1/POLG/PRKCE/HLA-DRB1/AGER",14]
["GO:0060292","long-term synaptic depression","8/267","31/18866",8.62540196209013e-09,8.64791807162972e-08,3.09756033261279e-08,"CD38/SRF/PTK2B/PLK2/SORCS3/PTEN/MAPT/AGER",8]
["GO:0051348","negative regulation of transferase activity","20/267","296/18866",8.89863153460635e-09,8.90398141328447e-08,3.1892785523249e-08,"GSK3B/SIRT1/TSC2/SFRP1/PRKAR1A/IFNG/DUSP1/IL1B/APOE/PPP1R1B/MEN1/DUSP6/TP53/AKT1/CDKN2A/PTEN/ADIPOQ/PRKN/MAPT/NF1",20]
["GO:0032386","regulation of intracellular transport","22/267","358/18866",8.96583211654702e-09,8.95327995158385e-08,3.20693658231861e-08,"PRKACA/PTGS2/GSK3B/MAPK1/MAPK3/TGFB1/MAPK8/IFNG/IL1B/MAP2K2/TP53/PIK3R1/SHH/CDK5/MAP2K1/BCL2/LEP/PTPN11/ADIPOQ/PRKN/LRRK2/NF1",22]
["GO:0031663","lipopolysaccharide-mediated signaling pathway","10/267","59/18866",9.29999870795749e-09,9.26844182611412e-08,3.31982304965223e-08,"MAPK1/MAPK3/TGFB1/CCL2/IL1B/AKT1/IL18/NOS3/PRKCE/TNF",10]
["GO:0072091","regulation of stem cell proliferation","11/267","76/18866",9.43279174884076e-09,9.38205760995257e-08,3.3605185953618e-08,"PAX6/HIF1A/VEGFA/TP53/DRD2/ACE/SHH/CTNNB1/BDNF/LRRK2/NF1",11]
["GO:0002685","regulation of leukocyte migration","17/267","212/18866",9.6289970927742e-09,9.55816749189296e-08,3.42359863150013e-08,"MAPK1/MAPK3/CCL2/VEGFA/DUSP1/PTK2B/RAC1/IL6/ADAM10/AKT1/IL6R/FADD/CXCL8/CSF1R/DPP4/AGER/TNF",17]
["GO:0050770","regulation of axonogenesis","16/267","186/18866",9.74934482122698e-09,9.65842831198141e-08,3.45951062056488e-08,"NGFR/GSK3B/ADNP/SRF/VEGFA/APOE/NGF/NTRK2/CDK5/RET/MAP2K1/PTEN/BDNF/MAPT/DCC/L1CAM",16]
["GO:0034968","histone lysine methylation","13/267","116/18866",1.02724241818259e-08,1.01564780078924e-07,3.63790488481962e-08,"BRCA1/ATRX/SIRT1/SMARCB1/KMT2A/DNMT1/MEN1/KDM6A/KMT2D/CTNNB1/MECP2/EHMT1/PAX5",13]
["GO:0030878","thyroid gland development","7/267","21/18866",1.03192913676201e-08,1.01826525293532e-07,3.64728022333818e-08,"TG/MAPK1/MAPK3/FGF8/SRF/SHH/MAP2K1",7]
["GO:0014015","positive regulation of gliogenesis","11/267","77/18866",1.08683560772228e-08,1.07032942590874e-07,3.83376663037506e-08,"TNFRSF1B/TSPO/TGFB1/IL1B/LIF/IL6/PRKCI/SHH/HDAC2/MTOR/TNF",11]
["GO:0035249","synaptic transmission, glutamatergic","12/267","96/18866",1.09767615524295e-08,1.0788773706945e-07,3.8643841437169e-08,"PTGS2/HTR2A/CCL2/CNR1/PTK2B/GLUL/DRD2/CDK5/PRKN/LRRK2/NF1/TNF",12]
["GO:0032722","positive regulation of chemokine production","9/267","45/18866",1.1303101950412e-08,1.10876990252273e-07,3.9714549092648e-08,"HIF1A/IL17A/IL1B/IL6/IL6R/LPL/ADIPOQ/AGER/TNF",9]
["GO:0010959","regulation of metal ion transport","23/267","396/18866",1.1758145708469e-08,1.15114552004678e-07,4.12323829900698e-08,"PRKACA/PTGS2/DLG1/BAX/P2RX7/TSPO/HTR2A/CCL2/IFNG/PDGFRB/PTK2B/ATF4/AKT1/DRD2/NOS3/CDK5/CTNNB1/PRKCE/CHD7/BCL2/PTEN/F2/DMD",23]
["GO:0043010","camera-type eye development","21/267","332/18866",1.1953165185685e-08,1.16794821471869e-07,4.18342314357376e-08,"PAX6/DLG1/BAX/HIF1A/SRF/VEGFA/PDGFRB/MFN2/ATF4/SLC6A3/NTRK2/DRD2/SHH/RET/FBN1/CTNNB1/CHD7/JUN/HDAC2/NF1/DLL1",21]
["GO:0007369","gastrulation","16/267","189/18866",1.22584225387019e-08,1.19543561983864e-07,4.28187908989607e-08,"COL11A1/FGFR2/PRKACA/FGFR1/SFRP1/FGF8/PRKAR1A/SRF/DUSP1/KDM6B/IL10/TP53/KDM6A/OTX2/CTNNB1/ADIPOQ",16]
["GO:0007569","cell aging","13/267","118/18866",1.26650748953642e-08,1.23268457997181e-07,4.41529952749027e-08,"SIRT1/SRF/KRAS/BRCA2/TP53/SOD1/PLK2/CDKN2A/MAP2K1/BCL2/PTEN/PAWR/MTOR",13]
["GO:0032102","negative regulation of response to external stimulus","24/267","433/18866",1.37744525638555e-08,1.33805139399475e-07,4.79270835674594e-08,"IGF1/TNFRSF1B/GRN/TNFRSF1A/CCL2/IL2/DUSP1/APOE/IL10/SOD1/SLC6A3/DRD2/NOS3/PTEN/LEP/F2/ADIPOQ/CCK/HLA-DRB1/DPP4/AGER/TNF/GPX1/INS",24]
["GO:0048538","thymus development","9/267","46/18866",1.3879980194872e-08,1.3444450594108e-07,4.81560955008369e-08,"MAPK1/MAPK3/SRF/SOD1/SHH/CTNNB1/FADD/MAP2K1/BCL2",9]
["GO:0050810","regulation of steroid biosynthetic process","12/267","98/18866",1.39210513862484e-08,1.3444450594108e-07,4.81560955008369e-08,"REST/APOB/SIRT1/TSPO/PPARGC1A/VDR/IFNG/IL1B/APOE/SOD1/LEP/TNF",12]
["GO:2001243","negative regulation of intrinsic apoptotic signaling pathway","12/267","98/18866",1.39210513862484e-08,1.3444450594108e-07,4.81560955008369e-08,"PTGS2/SIRT1/XBP1/HIF1A/SOD2/AKT1/BCL2L1/BCL2/PRKN/LRRK2/GPX1/INS",12]
["GO:0016575","histone deacetylation","11/267","79/18866",1.43369349642522e-08,1.38193660765466e-07,4.94989890352866e-08,"HDAC9/HDAC4/REST/HDAC6/SIRT1/MAPK8/VEGFA/PER2/TP53/LRRK2/HDAC2",11]
["GO:0034329","cell junction assembly","24/267","434/18866",1.43983194085892e-08,1.38517936044482e-07,4.9615139793516e-08,"PRKACA/DLG1/ADNP/OXT/SFRP1/SRF/VEGFA/PTK2B/IL1B/RAC1/NTRK2/DRD2/ACE/PDLIM5/PRKCI/CDK5/CTNNB1/MECP2/BCL2/PTEN/BDNF/ERBB4/GPC6/TNF",24]
["GO:0036294","cellular response to decreased oxygen levels","17/267","218/18866",1.46162650363125e-08,1.40344252550593e-07,5.02693001957389e-08,"CREBBP/PTGS2/SIRT1/EP300/HIF1A/SFRP1/PPARGC1A/VEGFA/ATF4/TP53/AKT1/S100B/PRKCE/BCL2/PTEN/MTOR/MALAT1",17]
["GO:2001242","regulation of intrinsic apoptotic signaling pathway","15/267","166/18866",1.46608473036993e-08,1.40502131645625e-07,5.03258502252451e-08,"PTGS2/BAX/SIRT1/XBP1/HIF1A/SOD2/TP53/SOD1/AKT1/BCL2L1/BCL2/PRKN/LRRK2/GPX1/INS",15]
["GO:0042359","vitamin D metabolic process","7/267","22/18866",1.49527672135058e-08,1.42751752766796e-07,5.11316322748241e-08,"FGFR1/VDR/IFNG/IL1B/CYP27A1/CYP3A4/TNF",7]
["GO:0051000","positive regulation of nitric-oxide synthase activity","7/267","22/18866",1.49527672135058e-08,1.42751752766796e-07,5.11316322748241e-08,"HIF1A/PTK2B/APOE/KRAS/AKT1/TNF/INS",7]
["GO:0051588","regulation of neurotransmitter transport","13/267","120/18866",1.55502198065725e-08,1.48172228042397e-07,5.30731688456541e-08,"GSK3B/HTR2A/CNR1/PER2/TOR1A/DRD2/CDK5/GDNF/SNCG/ATP2A2/PRKN/LRRK2/NF1",13]
["GO:0015837","amine transport","12/267","99/18866",1.56439702357021e-08,1.48781606451163e-07,5.32914394595645e-08,"P2RX7/OXT/HTR2A/CNR1/PER2/TOR1A/DRD2/GDNF/SNCG/LEP/PRKN/CCK",12]
["GO:0030225","macrophage differentiation","9/267","47/18866",1.69565961168878e-08,1.60653291103644e-07,5.75437067863623e-08,"SIRT1/TGFB1/IFNG/VEGFA/LIF/FADD/ADIPOQ/CSF1R/HLA-DRB1",9]
["GO:0048806","genitalia development","9/267","47/18866",1.69565961168878e-08,1.60653291103644e-07,5.75437067863623e-08,"BAX/ESR1/FGF8/SRD5A1/SHH/CTNNB1/AR/CHD7/PTPN11",9]
["GO:0032259","methylation","22/267","371/18866",1.70778029211127e-08,1.61495208305144e-07,5.78452694636574e-08,"CREBBP/BRCA1/ATRX/GNAS/COMT/SIRT1/SMARCB1/MTR/KMT2A/PIK3CA/DNMT1/PRMT7/MEN1/CYP1A2/KDM6A/KMT2D/CTNNB1/MECP2/FOS/MTHFR/EHMT1/PAX5",22]
["GO:0008585","female gonad development","12/267","100/18866",1.75559171616211e-08,1.65702635894091e-07,5.93523097355373e-08,"BAX/ESR1/SIRT1/SFRP1/VEGFA/BRCA2/SOD1/GNRH1/NOS3/BCL2L1/BCL2/LEP",12]
["GO:0006690","icosanoid metabolic process","13/267","122/18866",1.90161375238416e-08,1.78808991820228e-07,6.40468186202932e-08,"PON1/TNFRSF1A/PTGS2/SIRT1/CYP2D6/MAPK3/IL1B/CYP2E1/GSTM1/CYP1A2/CYP2C19/CYP2B6/GPX1",13]
["GO:0097237","cellular response to toxic substance","13/267","122/18866",1.90161375238416e-08,1.78808991820228e-07,6.40468186202932e-08,"PTGS2/SOD2/TPO/APOE/GSTM1/SOD1/ALB/NOS3/NQO1/PRKN/TNF/GPX1/HP",13]
["GO:2000241","regulation of reproductive process","15/267","170/18866",2.02416067545141e-08,1.89974328055054e-07,6.80460820655311e-08,"IGF1/HDAC4/ESR1/OXT/SFRP1/PRKAR1A/VEGFA/CNR1/DUSP1/LIF/GNRH1/SHH/CTNNB1/AR/HDAC2",15]
["GO:0051932","synaptic transmission, GABAergic","9/267","48/18866",2.06134816186394e-08,1.92739913336829e-07,6.90366750839117e-08,"TAC1/GABRA3/CNR1/KRAS/DRD2/PRKCE/PTEN/BDNF/NF1",9]
["GO:1900271","regulation of long-term synaptic potentiation","9/267","48/18866",2.06134816186394e-08,1.92739913336829e-07,6.90366750839117e-08,"GSK3B/CREB1/APOE/DRD2/SQSTM1/CALB2/NF1/AGER/INS",9]
["GO:1903799","negative regulation of production of miRNAs involved in gene silencing by miRNA","6/267","14/18866",2.0744010447958e-08,1.9359783956384e-07,6.93439719647432e-08,"ESR1/TGFB1/IL6/TP53/LIN28B/TNF",6]
["GO:0051570","regulation of histone H3-K9 methylation","7/267","23/18866",2.12358922554246e-08,1.97083290021069e-07,7.0592410373638e-08,"BRCA1/ATRX/SIRT1/SMARCB1/DNMT1/MECP2/PAX5",7]
["GO:0060149","negative regulation of posttranscriptional gene silencing","7/267","23/18866",2.12358922554246e-08,1.97083290021069e-07,7.0592410373638e-08,"ESR1/TGFB1/IL6/TP53/LIN28B/TNF/NEAT1",7]
["GO:0060967","negative regulation of gene silencing by RNA","7/267","23/18866",2.12358922554246e-08,1.97083290021069e-07,7.0592410373638e-08,"ESR1/TGFB1/IL6/TP53/LIN28B/TNF/NEAT1",7]
["GO:0021954","central nervous system neuron development","11/267","82/18866",2.13980160297118e-08,1.98219469455196e-07,7.09993735660195e-08,"FGFR2/GLI2/FGF8/NPY/NTRK2/DRD2/CDK5/PTEN/LEP/MAPT/DCC",11]
["GO:0051302","regulation of cell division","15/267","171/18866",2.1910115706927e-08,2.02587421712383e-07,7.25639114738188e-08,"PAX6/FGFR2/TGFB1/FGF8/VEGFA/IL1A/IL1B/BRCA2/PLK2/DRD2/SHH/PRKCE/BCL2L1/PTCH1/DLL1",15]
["GO:0055024","regulation of cardiac muscle tissue development","12/267","102/18866",2.20207252890624e-08,2.0285882171271e-07,7.26611230649001e-08,"IGF1/ERBB3/FGFR2/FGFR1/MAPK1/TGFB1/FGF8/CREB1/PTEN/ERBB4/DLL1/MTOR",12]
["GO:0060840","artery development","12/267","102/18866",2.20207252890624e-08,2.0285882171271e-07,7.26611230649001e-08,"NGFR/NOTCH3/APOB/FGF8/SRF/VEGFA/PDGFRB/APOE/SHH/CHD7/LEP/NF1",12]
["GO:0006694","steroid biosynthetic process","16/267","197/18866",2.21068010790898e-08,2.02903047404219e-07,7.26769640738652e-08,"REST/APOB/SIRT1/TSPO/PPARGC1A/VDR/IFNG/IL1B/APOE/CYP27A1/SOD1/LBR/SRD5A1/CYP3A4/LEP/TNF",16]
["GO:0048839","inner ear development","16/267","197/18866",2.21068010790898e-08,2.02903047404219e-07,7.26769640738652e-08,"COL11A1/FGFR2/GLI2/FGFR1/FGF8/PDGFRB/ADAM10/COL2A1/SOD1/HESX1/SHH/CHD7/BDNF/PTPN11/FZD2/DLL1",16]
["GO:0030217","T cell differentiation","18/267","253/18866",2.27941429595774e-08,2.08827808802147e-07,7.47991287075268e-08,"GLI2/XBP1/IL2/IFNG/SRF/IL1A/IL1B/IL6/TP53/SOD1/IL18/SHH/CTNNB1/FADD/CHD7/BCL2/LEP/MTOR",18]
["GO:0051384","response to glucocorticoid","14/267","147/18866",2.29185297118388e-08,2.09582818408811e-07,7.50695623296974e-08,"PTGS2/REST/OXT/NR3C1/DUSP1/KRAS/IL6/IL10/SRD5A1/S100B/FOS/BCL2/ADIPOQ/TNF",14]
["GO:0002688","regulation of leukocyte chemotaxis","13/267","124/18866",2.31646051622929e-08,2.11445838346121e-07,7.57368693750325e-08,"MAPK1/MAPK3/CCL2/VEGFA/DUSP1/PTK2B/RAC1/IL6/ADAM10/IL6R/CXCL8/CSF1R/DPP4",13]
["GO:0032228","regulation of synaptic transmission, GABAergic","8/267","35/18866",2.45031468448943e-08,2.22444022175559e-07,7.96762612238765e-08,"TAC1/CNR1/KRAS/DRD2/PRKCE/PTEN/BDNF/NF1",8]
["GO:0034390","smooth muscle cell apoptotic process","8/267","35/18866",2.45031468448943e-08,2.22444022175559e-07,7.96762612238765e-08,"IGF1/SIRT1/IFNG/SOD2/MFN2/ATF4/DNMT1/CDKN2A",8]
["GO:0034391","regulation of smooth muscle cell apoptotic process","8/267","35/18866",2.45031468448943e-08,2.22444022175559e-07,7.96762612238765e-08,"IGF1/SIRT1/IFNG/SOD2/MFN2/ATF4/DNMT1/CDKN2A",8]
["GO:0010573","vascular endothelial growth factor production","10/267","65/18866",2.45939587431732e-08,2.22643383910492e-07,7.97476697405687e-08,"BRCA1/PTGS2/HIF1A/TGFB1/IL1A/IL1B/ATF4/IL6/IL6R/TNF",10]
["GO:0008630","intrinsic apoptotic signaling pathway in response to DNA damage","12/267","103/18866",2.46142895891431e-08,2.22643383910492e-07,7.97476697405687e-08,"BRCA1/TNFRSF1B/TNFRSF1A/BAX/SIRT1/EP300/BRCA2/TP53/PIK3R1/BCL2L1/BCL2/TNF",12]
["GO:0030850","prostate gland development","9/267","49/18866",2.4941579923189e-08,2.2478936562542e-07,8.05163296399357e-08,"FGFR2/GLI2/ESR1/SFRP1/SHH/CTNNB1/AR/PTEN/PTCH1",9]
["GO:0061647","histone H3-K9 modification","9/267","49/18866",2.4941579923189e-08,2.2478936562542e-07,8.05163296399357e-08,"BRCA1/ATRX/SIRT1/SMARCB1/KMT2A/DNMT1/MECP2/EHMT1/PAX5",9]
["GO:0043254","regulation of protein-containing complex assembly","24/267","449/18866",2.75422465943385e-08,2.47780968009968e-07,8.8751592155109e-08,"DLG1/GSK3B/BAX/ESR1/HDAC6/EP300/TGFB1/IFNG/VEGFA/STMN1/CREB1/PTK2B/APOE/GFAP/RAC1/TP53/VCP/MECP2/PRKCE/PTPN11/MAPT/CCK/MTOR/TNF",24]
["GO:0045913","positive regulation of carbohydrate metabolic process","11/267","84/18866",2.76842535014298e-08,2.48610571461581e-07,8.90487442236448e-08,"IGF1/POU1F1/P2RX7/SIRT1/HIF1A/HTR2A/PPARGC1A/IFNG/AKT1/PRKCE/INS",11]
["GO:2000378","negative regulation of reactive oxygen species metabolic process","10/267","66/18866",2.86278076401401e-08,2.56622340300215e-07,9.19184450167213e-08,"BRCA1/HDAC6/TSPO/HIF1A/IL10/TP53/BCL2/PRKN/INS/HP",10]
["GO:0031334","positive regulation of protein-containing complex assembly","18/267","257/18866",2.90274819796872e-08,2.59738741083474e-07,9.30346951207104e-08,"DLG1/GSK3B/BAX/ESR1/TGFB1/IFNG/VEGFA/CREB1/PTK2B/RAC1/TP53/VCP/MECP2/PRKCE/MAPT/CCK/MTOR/TNF",18]
["GO:0010639","negative regulation of organelle organization","23/267","416/18866",2.93016323299814e-08,2.61722808986757e-07,9.37453598128959e-08,"GCLC/BRCA1/IGF1/ATRX/HDAC6/SIRT1/SMARCB1/TSPO/TSC2/PRKAR1A/PPARGC1A/STMN1/DUSP1/LIF/DNMT1/TP53/AKT1/BCL2L1/PRKN/MAPT/LRRK2/PAX5/GPX1",23]
["GO:0021700","developmental maturation","19/267","287/18866",2.93785267341066e-08,2.61941042827489e-07,9.38235280474569e-08,"IGF1/FGFR3/PRKACA/FGFR1/XBP1/HIF1A/VEGFA/PTK2B/BRCA2/RERE/RET/CTNNB1/MECP2/BCL2/PTEN/LEP/LRRK2/NF1/MTOR",19]
["GO:0035107","appendage morphogenesis","14/267","150/18866",2.96726166602539e-08,2.6362166367375e-07,9.44255023520721e-08,"CREBBP/FGFR2/GLI2/FGFR1/ATRX/BAX/GNAS/FGF8/COL2A1/SHH/CTNNB1/CHD7/PTCH1/HDAC2",14]
["GO:0035108","limb morphogenesis","14/267","150/18866",2.96726166602539e-08,2.6362166367375e-07,9.44255023520721e-08,"CREBBP/FGFR2/GLI2/FGFR1/ATRX/BAX/GNAS/FGF8/COL2A1/SHH/CTNNB1/CHD7/PTCH1/HDAC2",14]
["GO:0007631","feeding behavior","12/267","105/18866",3.06379373211989e-08,2.70752603619019e-07,9.69797028574138e-08,"OXT/OPRM1/CNR1/NPY/NTRK2/DRD2/FOS/LEP/BDNF/CCK/MTOR/INS",12]
["GO:0044070","regulation of anion transport","12/267","105/18866",3.06379373211989e-08,2.70752603619019e-07,9.69797028574138e-08,"FGFR1/ABCB1/P2RX7/OXT/IL1B/ATF4/APOE/PER2/AKT1/LEP/CCK/MTOR",12]
["GO:0046545","development of primary female sexual characteristics","12/267","105/18866",3.06379373211989e-08,2.70752603619019e-07,9.69797028574138e-08,"BAX/ESR1/SIRT1/SFRP1/VEGFA/BRCA2/SOD1/GNRH1/NOS3/BCL2L1/BCL2/LEP",12]
["GO:1901617","organic hydroxy compound biosynthetic process","18/267","258/18866",3.08131703882752e-08,2.71820070227311e-07,9.73620541002038e-08,"POU1F1/REST/APOB/SIRT1/VDR/IFNG/PTK2B/IL1B/APOE/PER2/CYP27A1/SOD1/SLC6A3/LBR/CYP3A4/LEP/TNF/MC1R",18]
["GO:1905477","positive regulation of protein localization to membrane","13/267","127/18866",3.09276020377578e-08,2.72348354452425e-07,9.75512779395721e-08,"DLG1/MAPK8/IFNG/TP53/AKT1/PIK3R1/SQSTM1/PRKCI/CDK5/PRKCE/BCL2/PRKN/TNF",13]
["GO:0016241","regulation of macroautophagy","15/267","176/18866",3.2289510924497e-08,2.83398488745965e-07,1.01509277700232e-07,"PRKACA/HDAC6/SIRT1/HIF1A/MAPK3/TSC2/MAPK8/MFN2/PIK3CA/TP53/AKT1/CDK5/PRKN/LRRK2/MTOR",15]
["GO:0051224","negative regulation of protein transport","14/267","151/18866",3.2295962366604e-08,2.83398488745965e-07,1.01509277700232e-07,"HDAC9/REST/SFRP1/OPRM1/IL1B/APOE/DRD2/CDK5/PTPN11/ADIPOQ/PRKN/LRRK2/NF1/INS",14]
["GO:0031060","regulation of histone methylation","10/267","67/18866",3.32347295945696e-08,2.911245699398e-07,1.04276649272712e-07,"BRCA1/ATRX/SIRT1/SMARCB1/KMT2A/DNMT1/CTNNB1/MECP2/MTHFR/PAX5",10]
["GO:0032091","negative regulation of protein binding","12/267","106/18866",3.41191369866692e-08,2.98217599445993e-07,1.06817270802016e-07,"GSK3B/BAX/ADNP/MAPK3/MAPK8/STMN1/IL10/AKT1/ACE/ATP2A2/ADIPOQ/LRRK2",12]
["GO:0042362","fat-soluble vitamin biosynthetic process","6/267","15/18866",3.41639228686377e-08,2.98217599445993e-07,1.06817270802016e-07,"VDR/IFNG/IL1B/CYP27A1/CYP3A4/TNF",6]
["GO:0001837","epithelial to mesenchymal transition","14/267","152/18866",3.51276301650551e-08,3.06094690076999e-07,1.09638731790996e-07,"FGFR2/FGFR1/GSK3B/HIF1A/SFRP1/TGFB1/FGF8/COL1A1/IL1B/IL6/CTNNB1/PTEN/HDAC2/MTOR",14]
["GO:2000106","regulation of leukocyte apoptotic process","11/267","86/18866",3.55644123017262e-08,3.09360819899859e-07,1.10808612691423e-07,"BAX/P2RX7/SIRT1/HIF1A/IL2/IDO1/IL10/TP53/CDKN2A/FADD/PTEN",11]
["GO:0045912","negative regulation of carbohydrate metabolic process","9/267","51/18866",3.6033419229457e-08,3.12895412543789e-07,1.12074653127409e-07,"HDAC4/GSK3B/EP300/TGFB1/PPARGC1A/TP53/ADIPOQ/PRKN/INS",9]
["GO:0006874","cellular calcium ion homeostasis","24/267","456/18866",3.69144320782984e-08,3.19989165567611e-07,1.1461553381036e-07,"CD38/TAC1/PRKACA/BAX/P2RX7/ESR1/OXT/HTR2A/IL2/VDR/CNR1/PTK2B/ATF4/APOE/DRD2/EDNRA/CDK5/PRKCE/CHD7/BCL2/CALB2/ATP2A2/F2/DMD",24]
["GO:1903426","regulation of reactive oxygen species biosynthetic process","12/267","107/18866",3.79506247993786e-08,3.28401160525646e-07,1.17628589864352e-07,"HDAC4/PTGS2/TSPO/IFNG/PTK2B/IL1B/RAC1/IL10/AKT1/MTOR/TNF/INS",12]
["GO:0032642","regulation of chemokine production","10/267","68/18866",3.84837648889038e-08,3.31864314491013e-07,1.1886904198936e-07,"HIF1A/IL17A/IL1B/IL6/IL10/IL6R/LPL/ADIPOQ/AGER/TNF",10]
["GO:0045428","regulation of nitric oxide biosynthetic process","10/267","68/18866",3.84837648889038e-08,3.31864314491013e-07,1.1886904198936e-07,"PTGS2/TSPO/IFNG/PTK2B/IL1B/RAC1/IL10/AKT1/MTOR/TNF",10]
["GO:0071542","dopaminergic neuron differentiation","8/267","37/18866",3.92223657276263e-08,3.37650469100066e-07,1.20941559657418e-07,"GSK3B/HIF1A/SFRP1/FGF8/VEGFA/SHH/OTX2/CTNNB1",8]
["GO:0033044","regulation of chromosome organization","21/267","356/18866",3.99785831181886e-08,3.43568098982987e-07,1.23061169884595e-07,"BRCA1/ATRX/SIRT1/SMARCB1/MAPK1/MAPK3/MAPK8/PPARGC1A/VEGFA/KMT2A/DUSP1/IL1B/LIF/DNMT1/TP53/CTNNB1/MECP2/MTHFR/MAPT/LRRK2/PAX5",21]
["GO:0032526","response to retinoic acid","12/267","108/18866",4.21630861523967e-08,3.61718709895046e-07,1.2956245862348e-07,"CD38/FGFR2/OXT/COL1A1/PDGFRB/CREB1/DUSP1/PTK2B/RET/LEP/PTCH1/HDAC2",12]
["GO:2000677","regulation of transcription regulatory region DNA binding","9/267","52/18866",4.30406008158704e-08,3.68613584688921e-07,1.32032103974296e-07,"PAX6/IGF1/EP300/GATA1/TGFB1/IFNG/LIF/PER2/CTNNB1",9]
["GO:0034976","response to endoplasmic reticulum stress","19/267","294/18866",4.31455288740606e-08,3.68879496007165e-07,1.32127349598106e-07,"GSK3B/BAX/SIRT1/XBP1/EP300/CCL2/ATF4/TOR1A/TP53/PIK3R1/ATF3/VCP/CXCL8/BCL2L1/BCL2/ATP2A2/JUN/PRKN/LRRK2",19]
["GO:0048863","stem cell differentiation","18/267","264/18866",4.38220264863467e-08,3.74022868797143e-07,1.33969632029335e-07,"FGFR2/REST/ESR1/MAPK1/HIF1A/GATA1/MAPK3/SFRP1/SRF/KMT2A/LIF/TP53/EDNRA/ACE/SHH/RET/GDNF/ERBB4",18]
["GO:0071453","cellular response to oxygen levels","17/267","235/18866",4.432827220795e-08,3.77592985734478e-07,1.35248396758172e-07,"CREBBP/PTGS2/SIRT1/EP300/HIF1A/SFRP1/PPARGC1A/VEGFA/ATF4/TP53/AKT1/S100B/PRKCE/BCL2/PTEN/MTOR/MALAT1",17]
["GO:0050866","negative regulation of cell activation","16/267","207/18866",4.43915647158298e-08,3.77592985734478e-07,1.35248396758172e-07,"GCLC/GRN/DLG1/SFRP1/PRKAR1A/IL2/CNR1/APOE/IDO1/IL10/GNRH1/SHH/NOS3/PAWR/F2/HLA-DRB1",16]
["GO:0019218","regulation of steroid metabolic process","13/267","131/18866",4.49079936684578e-08,3.81336075487431e-07,1.36589117870945e-07,"REST/APOB/SIRT1/TSPO/PPARGC1A/VDR/IFNG/GNB3/IL1B/APOE/SOD1/LEP/TNF",13]
["GO:0021510","spinal cord development","12/267","109/18866",4.67894902932599e-08,3.95965974634316e-07,1.41829338105706e-07,"PAX6/GLI2/AKT1/SRD5A1/SHH/GDNF/MED12/PTCH1/DCC/NF1/DLL1/MTOR",12]
["GO:0021761","limbic system development","12/267","109/18866",4.67894902932599e-08,3.95965974634316e-07,1.41829338105706e-07,"FGFR2/FGFR1/GSK3B/BAX/SRF/KDM6B/SRD5A1/DRD2/CDK5/ALK/PTEN/NF1",12]
["GO:0045766","positive regulation of angiogenesis","16/267","208/18866",4.74882593648846e-08,4.00521755082549e-07,1.43461153380048e-07,"BRCA1/GRN/HDAC9/PTGS2/SIRT1/XBP1/HIF1A/VEGFA/IL1A/PTK2B/IL1B/IL10/PLK2/NOS3/CXCL8/DLL1",16]
["GO:0071456","cellular response to hypoxia","16/267","208/18866",4.74882593648846e-08,4.00521755082549e-07,1.43461153380048e-07,"CREBBP/PTGS2/SIRT1/EP300/HIF1A/SFRP1/PPARGC1A/VEGFA/TP53/AKT1/S100B/PRKCE/BCL2/PTEN/MTOR/MALAT1",16]
["GO:0006869","lipid transport","22/267","393/18866",4.76519586850634e-08,4.01224670682161e-07,1.43712927675375e-07,"PON1/TAC1/NOS2/ACSL4/APOB/ABCB1/P2RX7/SIRT1/TSPO/OXT/POMC/IL1B/APOE/AKT1/DRD2/ACE/SHH/LEP/PTPN11/ADIPOQ/PRKN/PTCH1",22]
["GO:0031647","regulation of protein stability","19/267","296/18866",4.80503609501582e-08,4.03898067717407e-07,1.44670500184864e-07,"CREBBP/IGF1/GRN/HDAC6/SIRT1/MAPK1/XBP1/EP300/BAG1/PPARGC1A/CREB1/KRAS/TP53/PIK3R1/DVL3/BCL2/PTEN/PRKN/LRRK2",19]
["GO:0000187","activation of MAPK activity","14/267","156/18866",4.88441611919271e-08,4.09192779918275e-07,1.46566990224451e-07,"IGF1/P2RX7/MAPK1/MAPK3/IL1B/MAP2K2/DUSP6/SOD1/RET/MAP2K1/ALK/PTPN11/LRRK2/TNF",14]
["GO:0048592","eye morphogenesis","14/267","156/18866",4.88441611919271e-08,4.09192779918275e-07,1.46566990224451e-07,"PAX6/BAX/HIF1A/VEGFA/MFN2/ATF4/NTRK2/PRKCI/FBN1/CTNNB1/BCL2/BDNF/NF1/DLL1",14]
["GO:0051567","histone H3-K9 methylation","8/267","38/18866",4.90771040936318e-08,4.09362485640834e-07,1.46627776382467e-07,"BRCA1/ATRX/SIRT1/SMARCB1/DNMT1/MECP2/EHMT1/PAX5",8]
["GO:0071276","cellular response to cadmium ion","8/267","38/18866",4.90771040936318e-08,4.09362485640834e-07,1.46627776382467e-07,"MAPK1/MAPK3/MAPK8/CYP1A2/SOD1/AKT1/FOS/JUN",8]
["GO:0001101","response to acid chemical","13/267","132/18866",4.91923675915282e-08,4.09362485640834e-07,1.46627776382467e-07,"GCLC/XBP1/COL1A1/PPARGC1A/VEGFA/CREB1/DNMT1/NTRK2/SST/BCL2L1/MTHFR/MTOR/TNF",13]
["GO:0018022","peptidyl-lysine methylation","13/267","132/18866",4.91923675915282e-08,4.09362485640834e-07,1.46627776382467e-07,"BRCA1/ATRX/SIRT1/SMARCB1/KMT2A/DNMT1/MEN1/KDM6A/KMT2D/CTNNB1/MECP2/EHMT1/PAX5",13]
["GO:0032872","regulation of stress-activated MAPK cascade","17/267","237/18866",5.01781925847806e-08,4.16871406948102e-07,1.4931736439538e-07,"DLG1/MAPK1/MAPK3/SFRP1/VEGFA/DUSP1/PTK2B/IL1B/MAP2K2/MEN1/AKT1/DVL3/MAP2K1/LEP/PRKN/AGER/TNF",17]
["GO:0071356","cellular response to tumor necrosis factor","19/267","297/18866",5.06904630992661e-08,4.20427711386438e-07,1.50591181685003e-07,"BRCA1/TNFRSF1B/TNFRSF1A/HDAC4/APOB/SIRT1/MAPK1/MAPK3/SFRP1/CCL2/COL1A1/PPARGC1A/PTK2B/TP53/AKT1/CXCL8/ADIPOQ/PRKN/TNF",19]
["GO:0040029","regulation of gene expression, epigenetic","16/267","209/18866",5.07807332063498e-08,4.20477945106641e-07,1.50609174683754e-07,"BRCA1/ARID1B/HDAC4/HDAC6/SIRT1/EP300/TBP/DNMT1/PRMT7/KMT2D/CTNNB1/MECP2/MTHFR/HDAC2/HOTAIR/GPX1",16]
["GO:1904659","glucose transmembrane transport","12/267","110/18866",5.18652293676265e-08,4.28746838133376e-07,1.53570973676538e-07,"IGF1/IL1B/AKT1/PIK3R1/EDNRA/BRAF/PRKCI/LEP/PTPN11/ADIPOQ/TNF/INS",12]
["GO:0010594","regulation of endothelial cell migration","17/267","238/18866",5.33605201950675e-08,4.40378640221441e-07,1.57737318506167e-07,"GRN/HDAC9/PTGS2/FGFR1/SIRT1/HIF1A/TGFB1/VEGFA/PTK2B/APOE/GLUL/AKT1/PLK2/NOS3/MECP2/NF1/TNF",17]
["GO:0034764","positive regulation of transmembrane transport","16/267","210/18866",5.42800599472413e-08,4.4722828270062e-07,1.60190762290017e-07,"IGF1/ABCB1/BAX/P2RX7/CCL2/IFNG/AKT1/PIK3R1/BRAF/PRKCI/CDK5/PTPN11/F2/ADIPOQ/DMD/INS",16]
["GO:0045787","positive regulation of cell cycle","22/267","396/18866",5.4489419810331e-08,4.4821362951068e-07,1.60543699397819e-07,"BRCA1/IGF1/FGFR2/PRKACA/FGFR1/ATRX/BAX/EP300/FGF8/PDGFRB/IL1A/IL1B/IL10/BRCA2/TP53/AKT1/PLK2/DRD2/MECP2/PRKCE/PTPN11/INS",22]
["GO:0033673","negative regulation of kinase activity","18/267","268/18866",5.51127441908645e-08,4.52595282475307e-07,1.62113144702699e-07,"SIRT1/TSC2/SFRP1/PRKAR1A/IFNG/DUSP1/IL1B/APOE/PPP1R1B/MEN1/DUSP6/AKT1/CDKN2A/PTEN/ADIPOQ/PRKN/MAPT/NF1",18]
["GO:0030168","platelet activation","14/267","158/18866",5.73778671907524e-08,4.70423137739617e-07,1.68498826993498e-07,"GNAS/MAPK1/GATA1/MAPK3/COL1A1/SRF/PIK3CA/APOE/IL6/PIK3R1/NOS3/PRKCE/PTPN11/F2",14]
["GO:0070555","response to interleukin-1","16/267","211/18866",5.79978637526801e-08,4.74726776585462e-07,1.70040328758936e-07,"GCLC/CD38/VRK2/HDAC4/HIF1A/MAPK3/SFRP1/CCL2/IL17A/IL1A/IL1B/IL6/SQSTM1/PRKCI/CXCL8/MTHFR",16]
["GO:0055074","calcium ion homeostasis","24/267","468/18866",6.01535788305663e-08,4.91565988708703e-07,1.76071893243401e-07,"CD38/TAC1/PRKACA/BAX/P2RX7/ESR1/OXT/HTR2A/IL2/VDR/CNR1/PTK2B/ATF4/APOE/DRD2/EDNRA/CDK5/PRKCE/CHD7/BCL2/CALB2/ATP2A2/F2/DMD",24]
["GO:0070302","regulation of stress-activated protein kinase signaling cascade","17/267","240/18866",6.02853983455984e-08,4.91838225391459e-07,1.76169404522139e-07,"DLG1/MAPK1/MAPK3/SFRP1/VEGFA/DUSP1/PTK2B/IL1B/MAP2K2/MEN1/AKT1/DVL3/MAP2K1/LEP/PRKN/AGER/TNF",17]
["GO:0007431","salivary gland development","8/267","39/18866",6.09909321522153e-08,4.9678258439806e-07,1.77940403067938e-07,"PAX6/FGFR2/FGFR1/XBP1/TGFB1/FGF8/SHH/TNF",8]
["GO:0046849","bone remodeling","11/267","91/18866",6.46363121265274e-08,5.24762774711791e-07,1.87962506295199e-07,"CD38/P2RX7/SFRP1/TGFB1/PTK2B/RAC1/IL6/CTNNB1/LEP/CSF1R/NF1",11]
["GO:2000177","regulation of neural precursor cell proliferation","11/267","91/18866",6.46363121265274e-08,5.24762774711791e-07,1.87962506295199e-07,"PAX6/GLI2/HIF1A/VEGFA/TP53/DRD2/SHH/CTNNB1/BDNF/LRRK2/NF1",11]
["GO:0016051","carbohydrate biosynthetic process","16/267","213/18866",6.61382928309296e-08,5.36085220949402e-07,1.92018044292121e-07,"IGF1/POU1F1/GSK3B/SIRT1/EP300/TGFB1/PPARGC1A/PTK2B/ATF4/PER2/AKT1/ATF3/LEP/ADIPOQ/MTOR/INS",16]
["GO:0051937","catecholamine transport","10/267","72/18866",6.75324368690405e-08,5.46498310027746e-07,1.95747863585259e-07,"OXT/HTR2A/CNR1/TOR1A/SLC6A3/DRD2/GDNF/MECP2/SNCG/PRKN",10]
["GO:1903555","regulation of tumor necrosis factor superfamily cytokine production","12/267","113/18866",7.01818236564664e-08,5.66703989674915e-07,2.02985248496881e-07,"IGF1/TSPO/IFNG/POMC/IL10/PIK3R1/FADD/LEP/PTPN11/ADIPOQ/HDAC2/MC1R",12]
["GO:0050671","positive regulation of lymphocyte proliferation","13/267","136/18866",7.02563127596179e-08,5.66703989674915e-07,2.02985248496881e-07,"CD38/TAC1/IGF1/IL2/IL1A/IL1B/IL6/IL18/SHH/FADD/BCL2/LEP/AGER",13]
["GO:0002931","response to ischemia","9/267","55/18866",7.16810597273171e-08,5.77263760029829e-07,2.06767606921412e-07,"ARID1B/REST/P2RX7/PPARGC1A/PER2/TP53/SQSTM1/BCL2/CSF1R",9]
["GO:0043409","negative regulation of MAPK cascade","15/267","187/18866",7.24302996715204e-08,5.82358270949922e-07,2.08592387731016e-07,"DLG1/P2RX7/SFRP1/DUSP1/IL1B/LIF/APOE/MEN1/DUSP6/AKT1/ATF3/PTEN/ADIPOQ/PRKN/NF1",15]
["GO:0001963","synaptic transmission, dopaminergic","7/267","27/18866",7.32869038626244e-08,5.87353950218433e-07,2.10381768459236e-07,"PTGS2/TOR1A/SLC6A3/DRD2/CDK5/GDNF/PRKN",7]
["GO:0048143","astrocyte activation","7/267","27/18866",7.32869038626244e-08,5.87353950218433e-07,2.10381768459236e-07,"GRN/IFNG/IL1B/IL6/MAPT/AGER/TNF",7]
["GO:0002209","behavioral defense response","8/267","40/18866",7.53111611057789e-08,6.00684708308552e-07,2.15156654983552e-07,"EP300/APOE/MECP2/BCL2/BDNF/PENK/CCK/DPP4",8]
["GO:0090184","positive regulation of kidney development","8/267","40/18866",7.53111611057789e-08,6.00684708308552e-07,2.15156654983552e-07,"VEGFA/PDGFRB/LIF/IL6R/SHH/RET/GDNF/ADIPOQ",8]
["GO:0140353","lipid export from cell","8/267","40/18866",7.53111611057789e-08,6.00684708308552e-07,2.15156654983552e-07,"TAC1/NOS2/P2RX7/OXT/POMC/IL1B/LEP/PTPN11",8]
["GO:0032946","positive regulation of mononuclear cell proliferation","13/267","137/18866",7.66535320654866e-08,6.10416404470454e-07,2.18642409098064e-07,"CD38/TAC1/IGF1/IL2/IL1A/IL1B/IL6/IL18/SHH/FADD/BCL2/LEP/AGER",13]
["GO:0051966","regulation of synaptic transmission, glutamatergic","10/267","73/18866",7.72860468608793e-08,6.11978389847069e-07,2.19201889877443e-07,"PTGS2/HTR2A/CCL2/CNR1/PTK2B/GLUL/DRD2/CDK5/LRRK2/TNF",10]
["GO:0070227","lymphocyte apoptotic process","10/267","73/18866",7.72860468608793e-08,6.11978389847069e-07,2.19201889877443e-07,"BAX/P2RX7/HIF1A/IL2/IDO1/IL10/TP53/AKT1/FADD/PTEN",10]
["GO:0008645","hexose transmembrane transport","12/267","114/18866",7.74625159990682e-08,6.11978389847069e-07,2.19201889877443e-07,"IGF1/IL1B/AKT1/PIK3R1/EDNRA/BRAF/PRKCI/LEP/PTPN11/ADIPOQ/TNF/INS",12]
["GO:0043200","response to amino acid","12/267","114/18866",7.74625159990682e-08,6.11978389847069e-07,2.19201889877443e-07,"GCLC/XBP1/COL1A1/PPARGC1A/CREB1/DNMT1/NTRK2/SST/BCL2L1/MTHFR/MTOR/TNF",12]
["GO:1990748","cellular detoxification","12/267","114/18866",7.74625159990682e-08,6.11978389847069e-07,2.19201889877443e-07,"PTGS2/SOD2/TPO/APOE/GSTM1/SOD1/ALB/NOS3/NQO1/TNF/GPX1/HP",12]
["GO:0051651","maintenance of location in cell","16/267","216/18866",8.03124365445491e-08,6.33491304371144e-07,2.26907507589904e-07,"PRKACA/BAX/P2RX7/TSPO/HTR2A/PTK2B/APOE/SYNE1/AKT1/DRD2/ALB/CDK5/PRKCE/CHD7/F2/DMD",16]
["GO:0070228","regulation of lymphocyte apoptotic process","9/267","56/18866",8.43595962328318e-08,6.63318840929967e-07,2.37591303770545e-07,"BAX/P2RX7/HIF1A/IL2/IDO1/IL10/TP53/FADD/PTEN",9]
["GO:0090183","regulation of kidney development","9/267","56/18866",8.43595962328318e-08,6.63318840929967e-07,2.37591303770545e-07,"VEGFA/PDGFRB/LIF/IL6R/SHH/RET/CTNNB1/GDNF/ADIPOQ",9]
["GO:0006305","DNA alkylation","10/267","74/18866",8.82591176028421e-08,6.91801843313957e-07,2.4779350707631e-07,"BRCA1/ATRX/GNAS/KMT2A/PIK3CA/DNMT1/PRMT7/MECP2/FOS/EHMT1",10]
["GO:0006306","DNA methylation","10/267","74/18866",8.82591176028421e-08,6.91801843313957e-07,2.4779350707631e-07,"BRCA1/ATRX/GNAS/KMT2A/PIK3CA/DNMT1/PRMT7/MECP2/FOS/EHMT1",10]
["GO:0010660","regulation of muscle cell apoptotic process","11/267","94/18866",9.08327346757639e-08,7.0863725661889e-07,2.53823710878492e-07,"IGF1/SIRT1/IFNG/SOD2/MFN2/PTK2B/ATF4/DNMT1/TP53/CDKN2A/PTEN",11]
["GO:0060993","kidney morphogenesis","11/267","94/18866",9.08327346757639e-08,7.0863725661889e-07,2.53823710878492e-07,"DLG1/FGF8/VEGFA/PDGFRB/LIF/SHH/CTNNB1/GDNF/BCL2/PTCH1/LRRK2",11]
["GO:1905954","positive regulation of lipid localization","11/267","94/18866",9.08327346757639e-08,7.0863725661889e-07,2.53823710878492e-07,"PON1/TAC1/APOB/P2RX7/SIRT1/OXT/IL1B/APOE/LPL/ADIPOQ/PTCH1",11]
["GO:0001764","neuron migration","14/267","164/18866",9.16811238747631e-08,7.11918898144155e-07,2.54999147848445e-07,"PAX6/FGFR1/BAX/SRF/VEGFA/RAC1/GNRH1/NTRK2/DRD2/CDK5/CTNNB1/ERBB4/CCK/DCC",14]
["GO:0043535","regulation of blood vessel endothelial cell migration","14/267","164/18866",9.16811238747631e-08,7.11918898144155e-07,2.54999147848445e-07,"HDAC9/PTGS2/FGFR1/SIRT1/HIF1A/TGFB1/VEGFA/APOE/AKT1/PLK2/NOS3/MECP2/NF1/TNF",14]
["GO:0046165","alcohol biosynthetic process","14/267","164/18866",9.16811238747631e-08,7.11918898144155e-07,2.54999147848445e-07,"POU1F1/REST/APOB/VDR/IFNG/PTK2B/IL1B/APOE/CYP27A1/SOD1/LBR/CYP3A4/LEP/TNF",14]
["GO:0015749","monosaccharide transmembrane transport","12/267","116/18866",9.40810337709568e-08,7.29420188848427e-07,2.61267859393357e-07,"IGF1/IL1B/AKT1/PIK3R1/EDNRA/BRAF/PRKCI/LEP/PTPN11/ADIPOQ/TNF/INS",12]
["GO:0015980","energy derivation by oxidation of organic compounds","18/267","278/18866",9.5970113991383e-08,7.42912835905389e-07,2.66100732225801e-07,"NOS2/IGF1/GSK3B/GNAS/HIF1A/PPARGC1A/IFNG/POMC/PIK3CA/PER2/CYP1A2/TP53/AKT1/VCP/MECP2/LEP/MTOR/INS",18]
["GO:0032800","receptor biosynthetic process","7/267","28/18866",9.65406674114455e-08,7.46172681711064e-07,2.6726836228132e-07,"HDAC6/HIF1A/IFNG/IL10/ADIPOQ/HDAC2/TNF",7]
["GO:0045685","regulation of glial cell differentiation","10/267","75/18866",1.00580689874977e-07,7.74999050224939e-07,2.77593554414532e-07,"TNFRSF1B/TGFB1/LIF/IL6/SHH/CTNNB1/F2/HDAC2/NF1/MTOR",10]
["GO:1901983","regulation of protein acetylation","10/267","75/18866",1.00580689874977e-07,7.74999050224939e-07,2.77593554414532e-07,"BRCA1/GSK3B/SIRT1/SMARCB1/MAPK3/PPARGC1A/KMT2A/IL1B/LIF/HDAC2",10]
["GO:0006509","membrane protein ectodomain proteolysis","8/267","42/18866",1.12789754182677e-07,8.67733809913875e-07,3.10809816489121e-07,"TNFRSF1B/P2RX7/IFNG/IL1B/APOE/IL10/ADAM10/TNF",8]
["GO:0033559","unsaturated fatty acid metabolic process","12/267","118/18866",1.13815368603071e-07,8.72934155814337e-07,3.12672505872128e-07,"TNFRSF1A/PTGS2/SIRT1/CYP2D6/MAPK3/IL1B/CYP2E1/GSTM1/CYP1A2/CYP2C19/CYP2B6/GPX1",12]
["GO:0034219","carbohydrate transmembrane transport","12/267","118/18866",1.13815368603071e-07,8.72934155814337e-07,3.12672505872128e-07,"IGF1/IL1B/AKT1/PIK3R1/EDNRA/BRAF/PRKCI/LEP/PTPN11/ADIPOQ/TNF/INS",12]
["GO:0033077","T cell differentiation in thymus","10/267","76/18866",1.14390977469847e-07,8.76003298323536e-07,3.13771828739538e-07,"GLI2/SRF/IL1A/IL1B/TP53/SOD1/SHH/CTNNB1/FADD/BCL2",10]
["GO:0002687","positive regulation of leukocyte migration","13/267","142/18866",1.17197897942596e-07,8.96124202798442e-07,3.20978848399244e-07,"MAPK1/MAPK3/VEGFA/PTK2B/RAC1/IL6/ADAM10/IL6R/FADD/CXCL8/CSF1R/AGER/TNF",13]
["GO:0071560","cellular response to transforming growth factor beta stimulus","17/267","252/18866",1.22165341333537e-07,9.32678209905736e-07,3.34071969943151e-07,"CREBBP/FGFR2/SIRT1/EP300/SFRP1/TGFB1/COL1A1/PPARGC1A/NR3C1/CREB1/MEN1/TP53/FBN1/FOS/JUN/PENK/HDAC2",17]
["GO:0071706","tumor necrosis factor superfamily cytokine production","12/267","119/18866",1.25005032486689e-07,9.52900957566474e-07,3.41315468372656e-07,"IGF1/TSPO/IFNG/POMC/IL10/PIK3R1/FADD/LEP/PTPN11/ADIPOQ/HDAC2/MC1R",12]
["GO:0048873","homeostasis of number of cells within a tissue","7/267","29/18866",1.25727889896654e-07,9.55493689884316e-07,3.42244147936259e-07,"BAX/P2RX7/GATA1/KRAS/NOS3/BCL2/PTPN11",7]
["GO:2000108","positive regulation of leukocyte apoptotic process","7/267","29/18866",1.25727889896654e-07,9.55493689884316e-07,3.42244147936259e-07,"BAX/P2RX7/SIRT1/IDO1/IL10/TP53/CDKN2A",7]
["GO:0120162","positive regulation of cold-induced thermogenesis","11/267","97/18866",1.26054719438286e-07,9.56521602059818e-07,3.4261233134802e-07,"GNAS/OXT/PPARGC1A/VEGFA/MFN2/PER2/KDM6B/IL18/LEP/EHMT1/ADIPOQ",11]
["GO:0051924","regulation of calcium ion transport","17/267","253/18866",1.29323436131662e-07,9.79835988779039e-07,3.50963210586524e-07,"PRKACA/PTGS2/BAX/P2RX7/TSPO/CCL2/PDGFRB/PTK2B/DRD2/NOS3/CDK5/CTNNB1/PRKCE/CHD7/BCL2/F2/DMD",17]
["GO:0007422","peripheral nervous system development","10/267","77/18866",1.29842114991134e-07,9.80789228669792e-07,3.51304647455907e-07,"ERBB3/NGF/SOD1/AKT1/NTRK2/CDK5/GDNF/BDNF/MED12/NF1",10]
["GO:0072028","nephron morphogenesis","10/267","77/18866",1.29842114991134e-07,9.80789228669792e-07,3.51304647455907e-07,"DLG1/FGF8/VEGFA/PDGFRB/LIF/SHH/CTNNB1/GDNF/BCL2/PTCH1",10]
["GO:0001660","fever generation","5/267","10/18866",1.30065288543354e-07,9.809909149501e-07,3.51376888591443e-07,"PTGS2/IL1A/CNR1/IL1B/TNF",5]
["GO:0010657","muscle cell apoptotic process","11/267","98/18866",1.40232539536819e-07,1.05290386452231e-06,3.77135076649077e-07,"IGF1/SIRT1/IFNG/SOD2/MFN2/PTK2B/ATF4/DNMT1/TP53/CDKN2A/PTEN",11]
["GO:0014020","primary neural tube formation","11/267","98/18866",1.40232539536819e-07,1.05290386452231e-06,3.77135076649077e-07,"PRKACA/HIF1A/TSC2/SFRP1/TGFB1/KDM6A/DVL3/MTHFR/FZD2/MED12/PTCH1",11]
["GO:0044728","DNA methylation or demethylation","11/267","98/18866",1.40232539536819e-07,1.05290386452231e-06,3.77135076649077e-07,"BRCA1/ATRX/GNAS/KMT2A/PIK3CA/DNMT1/PRMT7/FTO/MECP2/FOS/EHMT1",11]
["GO:0051216","cartilage development","15/267","197/18866",1.43756750615417e-07,1.07774392766183e-06,3.86032431319098e-07,"COL11A1/FGFR3/GLI2/FGFR1/GNAS/HIF1A/MAPK3/TGFB1/COL1A1/SRF/COL2A1/CTNNB1/LEP/PTPN11/COL11A2",15]
["GO:0051403","stress-activated MAPK cascade","18/267","286/18866",1.46906865233595e-07,1.09949851419364e-06,3.93824612481683e-07,"DLG1/MAPK1/MAPK3/SFRP1/MAPK8/VEGFA/DUSP1/PTK2B/IL1B/MAP2K2/MEN1/AKT1/DVL3/MAP2K1/LEP/PRKN/AGER/TNF",18]
["GO:0060998","regulation of dendritic spine development","10/267","78/18866",1.47098940012287e-07,1.09949851419364e-06,3.93824612481683e-07,"IL2/APOE/ADAM10/PLK2/PDLIM5/CDK5/PTEN/LRRK2/HDAC2/MTOR",10]
["GO:0043414","macromolecule methylation","19/267","318/18866",1.48165701883574e-07,1.10581666592628e-06,3.9608768389614e-07,"CREBBP/BRCA1/ATRX/GNAS/SIRT1/SMARCB1/KMT2A/PIK3CA/DNMT1/PRMT7/MEN1/KDM6A/KMT2D/CTNNB1/MECP2/FOS/MTHFR/EHMT1/PAX5",19]
["GO:0120254","olefinic compound metabolic process","12/267","121/18866",1.50373517434228e-07,1.11894928844873e-06,4.00791601099306e-07,"PTGS2/REST/CYP2D6/MAPK3/PPARGC1A/CYP2E1/GSTM1/CYP1A2/SRD5A1/CYP2C19/CYP2B6/GPX1",12]
["GO:1900542","regulation of purine nucleotide metabolic process","12/267","121/18866",1.50373517434228e-07,1.11894928844873e-06,4.00791601099306e-07,"NOS2/IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/NOS3/VCP/INS",12]
["GO:0072503","cellular divalent inorganic cation homeostasis","24/267","492/18866",1.52084377116995e-07,1.12999597462077e-06,4.04748365792252e-07,"CD38/TAC1/PRKACA/BAX/P2RX7/ESR1/OXT/HTR2A/IL2/VDR/CNR1/PTK2B/ATF4/APOE/DRD2/EDNRA/CDK5/PRKCE/CHD7/BCL2/CALB2/ATP2A2/F2/DMD",24]
["GO:0030856","regulation of epithelial cell differentiation","14/267","171/18866",1.54385761189148e-07,1.14539094445381e-06,4.1026262338369e-07,"PAX6/TNFRSF1A/GSK3B/VDR/IFNG/VEGFA/IL1B/LIF/CTNNB1/GDNF/ADIPOQ/PTCH1/DLL1/TNF",14]
["GO:0061900","glial cell activation","9/267","60/18866",1.56685080074971e-07,1.16072493295894e-06,4.15755038337303e-07,"GRN/IFNG/IL1B/IL6/JUN/MAPT/LRRK2/AGER/TNF",9]
["GO:0031670","cellular response to nutrient","8/267","44/18866",1.65269531915441e-07,1.22250484867229e-06,4.37883718868358e-07,"XBP1/SFRP1/COL1A1/VDR/SRF/LEP/LPL/PENK",8]
["GO:0031016","pancreas development","10/267","79/18866",1.66339810309104e-07,1.22678681369772e-06,4.39417457381898e-07,"PAX6/GSK3B/XBP1/MEN1/IL6/AKT1/IL6R/SHH/CTNNB1/DLL1",10]
["GO:0043536","positive regulation of blood vessel endothelial cell migration","10/267","79/18866",1.66339810309104e-07,1.22678681369772e-06,4.39417457381898e-07,"HDAC9/PTGS2/FGFR1/SIRT1/HIF1A/TGFB1/VEGFA/AKT1/PLK2/NOS3",10]
["GO:0048705","skeletal system morphogenesis","16/267","228/18866",1.69081650301062e-07,1.24516914447375e-06,4.4600174485562e-07,"COL11A1/FGFR2/FGFR3/DLG1/FGFR1/GNAS/P2RX7/SFRP1/FGF8/COL1A1/PDGFRB/COL2A1/INPPL1/CTNNB1/MED12/PAX5",16]
["GO:0071559","response to transforming growth factor beta","17/267","258/18866",1.71197087421694e-07,1.25889110087852e-06,4.50916753010554e-07,"CREBBP/FGFR2/SIRT1/EP300/SFRP1/TGFB1/COL1A1/PPARGC1A/NR3C1/CREB1/MEN1/TP53/FBN1/FOS/JUN/PENK/HDAC2",17]
["GO:0050848","regulation of calcium-mediated signaling","11/267","100/18866",1.72893213271551e-07,1.2694938439189e-06,4.5471450363524e-07,"IGF1/ERBB3/PRKACA/GSK3B/PTK2B/CDH13/MAPT/LRRK2/MTOR/DMD/TNF",11]
["GO:1901654","response to ketone","15/267","200/18866",1.75116586917922e-07,1.28393115782847e-06,4.59885742597651e-07,"CD38/SIRT1/TSPO/OXT/SFRP1/TGFB1/NR3C1/DUSP1/AKT1/SRD5A1/GNRH1/AR/FOS/PRKCE/BCL2L1",15]
["GO:0060252","positive regulation of glial cell proliferation","6/267","19/18866",1.76588092558291e-07,1.29092876448543e-06,4.62392185029723e-07,"TSPO/IL1B/IL6/PRKCI/MTOR/TNF",6]
["GO:0060438","trachea development","6/267","19/18866",1.76588092558291e-07,1.29092876448543e-06,4.62392185029723e-07,"MAPK1/MAPK3/SRF/SHH/CTNNB1/MAP2K1",6]
["GO:0006836","neurotransmitter transport","16/267","229/18866",1.79505247113001e-07,1.30804350430084e-06,4.68522439585339e-07,"GSK3B/P2RX7/HTR2A/CNR1/PER2/GLUL/TOR1A/SLC6A3/DRD2/CDK5/GDNF/SNCG/ATP2A2/PRKN/LRRK2/NF1",16]
["GO:0050807","regulation of synapse organization","16/267","229/18866",1.79505247113001e-07,1.30804350430084e-06,4.68522439585339e-07,"ADNP/OXT/APOE/IL10/ADAM10/NTRK2/DRD2/PDLIM5/CDK5/VCP/PTEN/BDNF/GPC6/LRRK2/TNF/INS",16]
["GO:0007204","positive regulation of cytosolic calcium ion concentration","19/267","322/18866",1.7987950022272e-07,1.30804350430084e-06,4.68522439585339e-07,"CD38/TAC1/PRKACA/BAX/P2RX7/ESR1/OXT/HTR2A/IL2/CNR1/PTK2B/DRD2/EDNRA/CDK5/PRKCE/CHD7/BCL2/F2/DMD",19]
["GO:0006140","regulation of nucleotide metabolic process","12/267","123/18866",1.80239120961141e-07,1.30804350430084e-06,4.68522439585339e-07,"NOS2/IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/NOS3/VCP/INS",12]
["GO:0042471","ear morphogenesis","12/267","123/18866",1.80239120961141e-07,1.30804350430084e-06,4.68522439585339e-07,"COL11A1/FGFR2/GLI2/FGFR1/MAPK1/MAPK3/FGF8/COL2A1/SOD1/HESX1/CHD7/FZD2",12]
["GO:0046324","regulation of glucose import","9/267","61/18866",1.81550105706052e-07,1.30994173091086e-06,4.69202357156346e-07,"IGF1/AKT1/PIK3R1/PRKCI/LEP/PTPN11/ADIPOQ/TNF/INS",9]
["GO:0046888","negative regulation of hormone secretion","9/267","61/18866",1.81550105706052e-07,1.30994173091086e-06,4.69202357156346e-07,"REST/SFRP1/IL1B/LIF/DRD2/LEP/PTPN11/ADIPOQ/PRKN",9]
["GO:1902041","regulation of extrinsic apoptotic signaling pathway via death domain receptors","9/267","61/18866",1.81550105706052e-07,1.30994173091086e-06,4.69202357156346e-07,"BRCA1/GSK3B/SFRP1/ATF3/NOS3/FADD/BCL2L1/PTEN/GPX1",9]
["GO:2000756","regulation of peptidyl-lysine acetylation","9/267","61/18866",1.81550105706052e-07,1.30994173091086e-06,4.69202357156346e-07,"BRCA1/SIRT1/SMARCB1/MAPK3/PPARGC1A/KMT2A/IL1B/LIF/HDAC2",9]
["GO:0032945","negative regulation of mononuclear cell proliferation","10/267","80/18866",1.87757456859075e-07,1.35082562261868e-06,4.83846381318927e-07,"DLG1/PRKAR1A/IL2/IDO1/CRP/IL10/GNRH1/SHH/PAWR/HLA-DRB1",10]
["GO:0048678","response to axon injury","10/267","80/18866",1.87757456859075e-07,1.35082562261868e-06,4.83846381318927e-07,"GRN/BAX/TSPO/MTR/SOD1/DRD2/MAP2K1/BCL2/PTEN/JUN",10]
["GO:0071901","negative regulation of protein serine/threonine kinase activity","13/267","148/18866",1.9060569090733e-07,1.36934419381338e-06,4.90479468158355e-07,"SIRT1/SFRP1/PRKAR1A/DUSP1/IL1B/APOE/MEN1/DUSP6/AKT1/CDKN2A/PTEN/ADIPOQ/NF1",13]
["GO:0042180","cellular ketone metabolic process","17/267","260/18866",1.91156741159849e-07,1.3707135980761e-06,4.90969969142336e-07,"BRCA1/PTGS2/REST/COMT/SIRT1/PPARGC1A/CNR1/IL1B/IDO1/AKT1/SRD5A1/PRKCE/NQO1/ADIPOQ/CYP2B6/MTOR/INS",17]
["GO:0002792","negative regulation of peptide secretion","11/267","101/18866",1.91619886132009e-07,1.3707135980761e-06,4.90969969142336e-07,"HDAC9/REST/SFRP1/OPRM1/IL1B/APOE/DRD2/LEP/PTPN11/PRKN/INS",11]
["GO:0060191","regulation of lipase activity","11/267","101/18866",1.91619886132009e-07,1.3707135980761e-06,4.90969969142336e-07,"HDAC9/FGFR2/FGFR3/FGFR1/ESR1/HTR2A/PDGFRB/NTRK2/EDNRA/LPL/BDNF",11]
["GO:0051480","regulation of cytosolic calcium ion concentration","20/267","357/18866",1.95940983660303e-07,1.39961849987968e-06,5.01323290774572e-07,"CD38/TAC1/PRKACA/BAX/P2RX7/ESR1/OXT/HTR2A/IL2/CNR1/PTK2B/DRD2/EDNRA/CDK5/PRKCE/CHD7/BCL2/CALB2/F2/DMD",20]
["GO:0006721","terpenoid metabolic process","12/267","124/18866",1.97068533368159e-07,1.40566169586746e-06,5.03487876981207e-07,"APOB/CYP2D6/TTR/APOE/CYP2E1/CYP1A2/SRD5A1/CYP3A4/CYP2C19/LPL/GPC6/ADH1C",12]
["GO:0010828","positive regulation of glucose transmembrane transport","8/267","45/18866",1.98559570826799e-07,1.41226201871539e-06,5.05852018045781e-07,"IGF1/AKT1/PIK3R1/BRAF/PRKCI/PTPN11/ADIPOQ/INS",8]
["GO:0060443","mammary gland morphogenesis","8/267","45/18866",1.98559570826799e-07,1.41226201871539e-06,5.05852018045781e-07,"FGFR2/GLI2/BAX/ESR1/VDR/AR/CSF1R/PTCH1",8]
["GO:1901568","fatty acid derivative metabolic process","14/267","175/18866",2.05553127326033e-07,1.45992427416626e-06,5.22923954970323e-07,"PON1/TNFRSF1A/ACSL4/PTGS2/SIRT1/CYP2D6/MAPK3/IL1B/CYP2E1/GSTM1/CYP1A2/CYP2C19/CYP2B6/GPX1",14]
["GO:0010518","positive regulation of phospholipase activity","9/267","62/18866",2.09775707541333e-07,1.48568809610479e-06,5.32152186805113e-07,"FGFR2/FGFR3/FGFR1/ESR1/HTR2A/PDGFRB/NTRK2/EDNRA/BDNF",9]
["GO:0055025","positive regulation of cardiac muscle tissue development","9/267","62/18866",2.09775707541333e-07,1.48568809610479e-06,5.32152186805113e-07,"IGF1/ERBB3/FGFR2/FGFR1/MAPK1/TGFB1/CREB1/ERBB4/MTOR",9]
["GO:0019915","lipid storage","10/267","81/18866",2.11559873277917e-07,1.49620176668079e-06,5.35918032949428e-07,"APOB/SIRT1/IL1B/APOE/CRP/IL6/FTO/LEP/LPL/TNF",10]
["GO:0006473","protein acetylation","15/267","203/18866",2.12544848728063e-07,1.5010416261658e-06,5.3765160126402e-07,"CREBBP/BRCA1/GSK3B/SIRT1/SMARCB1/EP300/MAPK3/PPARGC1A/KMT2A/IL1B/LIF/BRCA2/MECP2/MAPT/HDAC2",15]
["GO:1903578","regulation of ATP metabolic process","12/267","125/18866",2.15284939588868e-07,1.51824534373901e-06,5.43813726377471e-07,"IGF1/HDAC4/P2RX7/TSPO/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/TP53/VCP/INS",12]
["GO:0060348","bone development","15/267","204/18866",2.26542598147461e-07,1.59538391050814e-06,5.71443655634379e-07,"IGF1/FGFR2/FGFR3/GNAS/EP300/FGF8/COL1A1/SRF/COL2A1/TP53/SRD5A1/INPPL1/FBN1/LEP/PTPN11",15]
["GO:0048709","oligodendrocyte differentiation","11/267","103/18866",2.34540150271337e-07,1.64705902996454e-06,5.89952942943226e-07,"PAX6/TNFRSF1B/NTRK2/SHH/CDK5/CTNNB1/PTEN/MED12/HDAC2/NF1/MTOR",11]
["GO:0098869","cellular oxidant detoxification","11/267","103/18866",2.34540150271337e-07,1.64705902996454e-06,5.89952942943226e-07,"PTGS2/SOD2/TPO/APOE/SOD1/ALB/NOS3/NQO1/TNF/GPX1/HP",11]
["GO:0051573","negative regulation of histone H3-K9 methylation","5/267","11/18866",2.35696733125388e-07,1.6482265945309e-06,5.90371147840238e-07,"BRCA1/SIRT1/SMARCB1/DNMT1/PAX5",5]
["GO:0060439","trachea morphogenesis","5/267","11/18866",2.35696733125388e-07,1.6482265945309e-06,5.90371147840238e-07,"MAPK1/MAPK3/SHH/CTNNB1/MAP2K1",5]
["GO:1903800","positive regulation of production of miRNAs involved in gene silencing by miRNA","5/267","11/18866",2.35696733125388e-07,1.6482265945309e-06,5.90371147840238e-07,"TGFB1/MAP2K2/IL6/TP53/MAP2K1",5]
["GO:0031641","regulation of myelination","8/267","46/18866",2.37439484644048e-07,1.65809139416466e-06,5.93904577711059e-07,"TNFRSF1B/TG/DLG1/AKT1/S100B/CTNNB1/PTEN/MTOR",8]
["GO:1902930","regulation of alcohol biosynthetic process","10/267","82/18866",2.3797124234017e-07,1.65948381704535e-06,5.94403323634151e-07,"POU1F1/REST/APOB/VDR/IFNG/PTK2B/IL1B/APOE/SOD1/TNF",10]
["GO:0042113","B cell activation","19/267","328/18866",2.39228800659994e-07,1.66592664113717e-06,5.96711050901168e-07,"CD38/HDAC9/POU1F1/HDAC4/BAX/XBP1/EP300/SFRP1/TGFB1/IL2/PTK2B/IL6/IL10/TP53/PIK3R1/BCL2/PAWR/IFNA1/DLL1",19]
["GO:0070059","intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress","9/267","63/18866",2.41738237894903e-07,1.68105713343906e-06,6.02130576430787e-07,"BAX/SIRT1/XBP1/ATF4/TP53/BCL2L1/BCL2/PRKN/LRRK2",9]
["GO:0070932","histone H3 deacetylation","6/267","20/18866",2.49284404437453e-07,1.73112243582226e-06,6.20063250331942e-07,"HDAC9/HDAC4/HDAC6/SIRT1/PER2/HDAC2",6]
["GO:0042176","regulation of protein catabolic process","21/267","397/18866",2.50448894896694e-07,1.7367935169711e-06,6.22094550335501e-07,"GCLC/NOS2/TNFRSF1B/PRKACA/GSK3B/IFNG/PTK2B/IL1B/APOE/GFAP/IL10/AKT1/PLK2/SHH/VCP/PTEN/PRKN/LRRK2/TNF/GPX1/INS",21]
["GO:0060603","mammary gland duct morphogenesis","7/267","32/18866",2.61473989588656e-07,1.81073457699883e-06,6.48579178496424e-07,"FGFR2/GLI2/ESR1/VDR/AR/CSF1R/PTCH1",7]
["GO:0046686","response to cadmium ion","9/267","64/18866",2.77847507596197e-07,1.92145790225459e-06,6.88238686989268e-07,"GCLC/MAPK1/MAPK3/MAPK8/CYP1A2/SOD1/AKT1/FOS/JUN",9]
["GO:0031098","stress-activated protein kinase signaling cascade","18/267","300/18866",2.9866875279078e-07,2.06050201704694e-06,7.38042296470374e-07,"DLG1/MAPK1/MAPK3/SFRP1/MAPK8/VEGFA/DUSP1/PTK2B/IL1B/MAP2K2/MEN1/AKT1/DVL3/MAP2K1/LEP/PRKN/AGER/TNF",18]
["GO:0015844","monoamine transport","10/267","84/18866",2.99604338949745e-07,2.06050201704694e-06,7.38042296470374e-07,"OXT/HTR2A/CNR1/TOR1A/SLC6A3/DRD2/GDNF/MECP2/SNCG/PRKN",10]
["GO:0030279","negative regulation of ossification","10/267","84/18866",2.99604338949745e-07,2.06050201704694e-06,7.38042296470374e-07,"HDAC4/HIF1A/GATA1/SFRP1/PTK2B/MEN1/BCL2/PTCH1/TNF/TWIST2",10]
["GO:0050886","endocrine process","10/267","84/18866",2.99604338949745e-07,2.06050201704694e-06,7.38042296470374e-07,"TAC1/FGFR1/GNAS/POMC/IL1B/KRAS/ACE/NOS3/LEP/PTPN11",10]
["GO:0046394","carboxylic acid biosynthetic process","20/267","367/18866",3.0464042272259e-07,2.09225533790081e-06,7.49415880989908e-07,"BRCA1/PTGS2/FOLH1/SIRT1/CYP2D6/XBP1/TGFB1/MTR/IL1B/CYP2E1/IDO1/PER2/GSTM1/GLUL/CYP27A1/CYP1A2/CYP3A4/LPL/MTHFR/ADIPOQ",20]
["GO:0048736","appendage development","14/267","181/18866",3.1118290706657e-07,2.1313254526521e-06,7.63410236237242e-07,"CREBBP/FGFR2/GLI2/FGFR1/ATRX/BAX/GNAS/FGF8/COL2A1/SHH/CTNNB1/CHD7/PTCH1/HDAC2",14]
["GO:0060173","limb development","14/267","181/18866",3.1118290706657e-07,2.1313254526521e-06,7.63410236237242e-07,"CREBBP/FGFR2/GLI2/FGFR1/ATRX/BAX/GNAS/FGF8/COL2A1/SHH/CTNNB1/CHD7/PTCH1/HDAC2",14]
["GO:0001841","neural tube formation","11/267","106/18866",3.14895353261762e-07,2.15379794361093e-06,7.71459560478346e-07,"PRKACA/HIF1A/TSC2/SFRP1/TGFB1/KDM6A/DVL3/MTHFR/FZD2/MED12/PTCH1",11]
["GO:0016053","organic acid biosynthetic process","20/267","368/18866",3.18106888809778e-07,2.17278754559127e-06,7.78261363795539e-07,"BRCA1/PTGS2/FOLH1/SIRT1/CYP2D6/XBP1/TGFB1/MTR/IL1B/CYP2E1/IDO1/PER2/GSTM1/GLUL/CYP27A1/CYP1A2/CYP3A4/LPL/MTHFR/ADIPOQ",20]
["GO:0050773","regulation of dendrite development","13/267","155/18866",3.26469641305946e-07,2.22686191125764e-06,7.97630026716713e-07,"GSK3B/IL2/APOE/ADAM10/PLK2/PDLIM5/CDK5/ALK/PTEN/DCC/LRRK2/HDAC2/MTOR",13]
["GO:0090068","positive regulation of cell cycle process","18/267","302/18866",3.29378771152438e-07,2.2436401150943e-06,8.03639738907147e-07,"BRCA1/IGF1/PRKACA/FGFR1/ATRX/BAX/EP300/FGF8/PDGFRB/IL1A/IL1B/TP53/AKT1/PLK2/DRD2/MECP2/PRKCE/INS",18]
["GO:0090316","positive regulation of intracellular protein transport","14/267","182/18866",3.32903023438769e-07,2.26455694281985e-06,8.11131846870024e-07,"PRKACA/PTGS2/GSK3B/MAPK1/TGFB1/MAPK8/IFNG/IL1B/TP53/PIK3R1/SHH/CDK5/BCL2/LEP",14]
["GO:0060324","face development","8/267","48/18866",3.35077396271199e-07,2.27201314799374e-06,8.13802552719356e-07,"MAPK1/EP300/MAPK3/COL1A1/SRF/MAP2K1/CHD7/PTPN11",8]
["GO:0010507","negative regulation of autophagy","10/267","85/18866",3.35364247961423e-07,2.27201314799374e-06,8.13802552719356e-07,"TSPO/TSC2/PIK3CA/IL10/TP53/AKT1/BCL2/LEP/LRRK2/MTOR",10]
["GO:0032092","positive regulation of protein binding","10/267","85/18866",3.35364247961423e-07,2.27201314799374e-06,8.13802552719356e-07,"GSK3B/EP300/APOE/MEN1/PLK2/ACE/CDK5/BDNF/PRKN/LRRK2",10]
["GO:0050803","regulation of synapse structure or activity","16/267","240/18866",3.3945370359982e-07,2.29660208953103e-06,8.22609959229917e-07,"ADNP/OXT/APOE/IL10/ADAM10/NTRK2/DRD2/PDLIM5/CDK5/VCP/PTEN/BDNF/GPC6/LRRK2/TNF/INS",16]
["GO:0009110","vitamin biosynthetic process","6/267","21/18866",3.44870449665386e-07,2.32694345294497e-06,8.33477800827157e-07,"VDR/IFNG/IL1B/CYP27A1/CYP3A4/TNF",6]
["GO:1903204","negative regulation of oxidative stress-induced neuron death","6/267","21/18866",3.44870449665386e-07,2.32694345294497e-06,8.33477800827157e-07,"REST/HIF1A/ATF4/IL10/CTNNB1/PRKN",6]
["GO:1903522","regulation of blood circulation","18/267","303/18866",3.45789629973381e-07,2.32999679144007e-06,8.34571462923183e-07,"CD38/TAC1/HDAC4/PRKACA/PTGS2/DLG1/OXT/HTR2A/IL2/PER2/AKT1/DRD2/ACE/NOS3/ATP2A2/LEP/DMD/AGER",18]
["GO:0001890","placenta development","13/267","156/18866",3.51708321316312e-07,2.36668416217297e-06,8.47712353406744e-07,"FGFR2/PTGS2/MAPK1/HIF1A/MAPK3/VDR/LIF/MEN1/IL10/SOD1/AKT1/MAP2K1/LEP",13]
["GO:0055001","muscle cell development","14/267","183/18866",3.55977181945363e-07,2.3921858269895e-06,8.56846684317024e-07,"IGF1/HDAC9/HDAC4/PRKAR1A/SRF/VEGFA/PDGFRB/PDLIM5/BCL2/ATP2A2/NEB/MTOR/DMD/GPX1",14]
["GO:0050772","positive regulation of axonogenesis","10/267","86/18866",3.74811594758751e-07,2.50862505714537e-06,8.98553548038828e-07,"NGFR/ADNP/SRF/VEGFA/NGF/NTRK2/MAP2K1/BDNF/MAPT/L1CAM",10]
["GO:0070664","negative regulation of leukocyte proliferation","10/267","86/18866",3.74811594758751e-07,2.50862505714537e-06,8.98553548038828e-07,"DLG1/PRKAR1A/IL2/IDO1/CRP/IL10/GNRH1/SHH/PAWR/HLA-DRB1",10]
["GO:0097756","negative regulation of blood vessel diameter","10/267","86/18866",3.74811594758751e-07,2.50862505714537e-06,8.98553548038828e-07,"CD38/PTGS2/HTR2A/PER2/CRP/AKT1/EDNRA/ACE/LEP/INS",10]
["GO:0043271","negative regulation of ion transport","13/267","157/18866",3.78679041152082e-07,2.53111707158279e-06,9.06609865310206e-07,"PTGS2/HTR2A/CNR1/PTK2B/ATF4/AKT1/DRD2/NOS3/PRKCE/BCL2/PTEN/LEP/MTOR",13]
["GO:0010595","positive regulation of endothelial cell migration","12/267","132/18866",3.90732575858904e-07,2.60819218083356e-06,9.34217064993354e-07,"GRN/HDAC9/PTGS2/FGFR1/SIRT1/HIF1A/TGFB1/VEGFA/PTK2B/AKT1/PLK2/NOS3",12]
["GO:0007595","lactation","8/267","49/18866",3.95591701900078e-07,2.62309344965085e-06,9.39554485955452e-07,"XBP1/HIF1A/VDR/VEGFA/CREB1/SLC6A3/PRL/ERBB4",8]
["GO:0015872","dopamine transport","8/267","49/18866",3.95591701900078e-07,2.62309344965085e-06,9.39554485955452e-07,"HTR2A/CNR1/TOR1A/SLC6A3/DRD2/GDNF/SNCG/PRKN",8]
["GO:0035196","production of miRNAs involved in gene silencing by miRNA","8/267","49/18866",3.95591701900078e-07,2.62309344965085e-06,9.39554485955452e-07,"ESR1/TGFB1/MAP2K2/IL6/TP53/MAP2K1/LIN28B/TNF",8]
["GO:0048641","regulation of skeletal muscle tissue development","8/267","49/18866",3.95591701900078e-07,2.62309344965085e-06,9.39554485955452e-07,"HDAC9/HDAC4/TGFB1/S100B/SHH/CTNNB1/BCL2/DLL1",8]
["GO:1990090","cellular response to nerve growth factor stimulus","8/267","49/18866",3.95591701900078e-07,2.62309344965085e-06,9.39554485955452e-07,"TAC1/CREB1/NGF/AKT1/NTRK2/PTEN/BDNF/MAPT",8]
["GO:0048148","behavioral response to cocaine","5/267","12/18866",3.99382454535027e-07,2.63423592535454e-06,9.43545561086019e-07,"HTR2A/PPP1R1B/DRD2/CDK5/FADD",5]
["GO:0051583","dopamine uptake involved in synaptic transmission","5/267","12/18866",3.99382454535027e-07,2.63423592535454e-06,9.43545561086019e-07,"TOR1A/SLC6A3/DRD2/GDNF/PRKN",5]
["GO:0051934","catecholamine uptake involved in synaptic transmission","5/267","12/18866",3.99382454535027e-07,2.63423592535454e-06,9.43545561086019e-07,"TOR1A/SLC6A3/DRD2/GDNF/PRKN",5]
["GO:0060736","prostate gland growth","5/267","12/18866",3.99382454535027e-07,2.63423592535454e-06,9.43545561086019e-07,"FGFR2/ESR1/SHH/AR/PTEN",5]
["GO:0035051","cardiocyte differentiation","13/267","158/18866",4.0748535330034e-07,2.67998118026463e-06,9.59930855886578e-07,"IGF1/REST/MAPK1/MAPK3/TGFB1/SRF/VEGFA/PDGFRB/KDM6B/PDLIM5/NEB/DLL1/MTOR",13]
["GO:0043276","anoikis","7/267","34/18866",4.07928238934732e-07,2.67998118026463e-06,9.59930855886578e-07,"TSC2/PIK3CA/AKT1/NTRK2/BCL2/TLE1/MTOR",7]
["GO:0050715","positive regulation of cytokine secretion","7/267","34/18866",4.07928238934732e-07,2.67998118026463e-06,9.59930855886578e-07,"P2RX7/IFNG/IL1A/IL10/DRD2/TNF/INS",7]
["GO:0018958","phenol-containing compound metabolic process","11/267","109/18866",4.18686513019411e-07,2.74704567609188e-06,9.83952397288858e-07,"TG/COMT/TPO/CYP2E1/SLC6A3/SRD5A1/DRD2/BCL2/PRKN/MAOA/MC1R",11]
["GO:0032675","regulation of interleukin-6 production","13/267","159/18866",4.38236056293365e-07,2.8715388832976e-06,1.02854408018017e-06,"P2RX7/XBP1/IFNG/IL17A/IL1A/IL1B/IL6/IL10/IL6R/LPL/PTPN11/AGER/TNF",13]
["GO:0032680","regulation of tumor necrosis factor production","11/267","110/18866",4.59444433425168e-07,3.00262572786893e-06,1.07549750949209e-06,"IGF1/TSPO/POMC/IL10/PIK3R1/FADD/LEP/PTPN11/ADIPOQ/HDAC2/MC1R",11]
["GO:0072009","nephron epithelium development","11/267","110/18866",4.59444433425168e-07,3.00262572786893e-06,1.07549750949209e-06,"DLG1/FGF8/VEGFA/LIF/SHH/CTNNB1/GDNF/BCL2/ADIPOQ/PTCH1/DLL1",11]
["GO:0034754","cellular hormone metabolic process","12/267","134/18866",4.60070626063281e-07,3.0027877593908e-06,1.07555554686139e-06,"REST/ESR1/COMT/CYP2D6/TSPO/PPARGC1A/TTR/CYP1A2/SRD5A1/CYP3A4/SHH/ADH1C",12]
["GO:0001774","microglial cell activation","8/267","50/18866",4.65219975863562e-07,3.02060252208942e-06,1.08193653958277e-06,"GRN/IFNG/IL6/JUN/MAPT/LRRK2/AGER/TNF",8]
["GO:0002269","leukocyte activation involved in inflammatory response","8/267","50/18866",4.65219975863562e-07,3.02060252208942e-06,1.08193653958277e-06,"GRN/IFNG/IL6/JUN/MAPT/LRRK2/AGER/TNF",8]
["GO:0050873","brown fat cell differentiation","8/267","50/18866",4.65219975863562e-07,3.02060252208942e-06,1.08193653958277e-06,"PTGS2/SIRT1/PPARGC1A/FTO/LEP/ADIPOQ/MTOR/INS",8]
["GO:1903580","positive regulation of ATP metabolic process","8/267","50/18866",4.65219975863562e-07,3.02060252208942e-06,1.08193653958277e-06,"IGF1/P2RX7/HIF1A/HTR2A/PPARGC1A/IFNG/VCP/INS",8]
["GO:0051900","regulation of mitochondrial depolarization","6/267","22/18866",4.6858958058484e-07,3.0385295790391e-06,1.08835775449575e-06,"GCLC/P2RX7/TSPO/BCL2/CCK/LRRK2",6]
["GO:0006469","negative regulation of protein kinase activity","16/267","246/18866",4.73205067900747e-07,3.06447847474504e-06,1.09765227710201e-06,"SIRT1/TSC2/SFRP1/PRKAR1A/IFNG/DUSP1/IL1B/APOE/PPP1R1B/MEN1/DUSP6/AKT1/CDKN2A/PTEN/ADIPOQ/NF1",16]
["GO:0010810","regulation of cell-substrate adhesion","15/267","217/18866",5.01816389055823e-07,3.24555599812918e-06,1.16251165122149e-06,"GSK3B/OLFM4/SFRP1/COL1A1/VEGFA/PTK2B/MEN1/RAC1/CDH13/PIK3R1/CDKN2A/PRKCE/BCL2/PTEN/NF1",15]
["GO:0061387","regulation of extent of cell growth","11/267","111/18866",5.03666212069711e-07,3.24567234606743e-06,1.16255332538577e-06,"GSK3B/ADNP/SRF/VEGFA/APOE/NGF/CDK5/BDNF/MAPT/DCC/L1CAM",11]
["GO:0007435","salivary gland morphogenesis","7/267","35/18866",5.03784511957192e-07,3.24567234606743e-06,1.16255332538577e-06,"PAX6/FGFR2/FGFR1/TGFB1/FGF8/SHH/TNF",7]
["GO:0060251","regulation of glial cell proliferation","7/267","35/18866",5.03784511957192e-07,3.24567234606743e-06,1.16255332538577e-06,"TSPO/CREB1/IL1B/IL6/PRKCI/MTOR/TNF",7]
["GO:0010565","regulation of cellular ketone metabolic process","14/267","189/18866",5.27256766126737e-07,3.38914778915567e-06,1.21394417316358e-06,"BRCA1/PTGS2/REST/COMT/SIRT1/PPARGC1A/CNR1/IL1B/AKT1/PRKCE/NQO1/ADIPOQ/MTOR/INS",14]
["GO:0043543","protein acylation","16/267","248/18866",5.27411943155208e-07,3.38914778915567e-06,1.21394417316358e-06,"CREBBP/BRCA1/GSK3B/SIRT1/SMARCB1/EP300/MAPK3/PPARGC1A/KMT2A/IL1B/LIF/GLUL/BRCA2/MECP2/MAPT/HDAC2",16]
["GO:0048662","negative regulation of smooth muscle cell proliferation","9/267","69/18866",5.37563012535183e-07,3.4499384596249e-06,1.23571852022362e-06,"COMT/PPARGC1A/IFNG/SOD2/MFN2/IL10/NOS3/PTEN/ADIPOQ",9]
["GO:0006984","ER-nucleus signaling pathway","8/267","51/18866",5.45068637562932e-07,3.48913808634836e-06,1.24975926480354e-06,"GSK3B/XBP1/CCL2/ATF4/TP53/ATF3/CXCL8/ATP2A2",8]
["GO:0035272","exocrine system development","8/267","51/18866",5.45068637562932e-07,3.48913808634836e-06,1.24975926480354e-06,"PAX6/FGFR2/FGFR1/XBP1/TGFB1/FGF8/SHH/TNF",8]
["GO:0099565","chemical synaptic transmission, postsynaptic","11/267","112/18866",5.51603007183964e-07,3.52644534554357e-06,1.26312219045159e-06,"GSK3B/P2RX7/OPRM1/PTK2B/AKT1/DRD2/CDK5/MECP2/PTEN/BDNF/LRRK2",11]
["GO:0043470","regulation of carbohydrate catabolic process","10/267","90/18866",5.76228340898218e-07,3.6744675684608e-06,1.31614162961091e-06,"IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/TP53/INS",10]
["GO:0098773","skin epidermis development","10/267","90/18866",5.76228340898218e-07,3.6744675684608e-06,1.31614162961091e-06,"NGFR/FGFR2/GLI2/SHH/CTNNB1/BCL2/HDAC2/NF1/DLL1/TNF",10]
["GO:0031214","biomineral tissue development","13/267","163/18866",5.83054591103923e-07,3.70852429730177e-06,1.32834026186465e-06,"IGF1/FGFR2/FGFR3/PTGS2/P2RX7/HIF1A/GATA1/TGFB1/COL1A1/PTK2B/ATF4/NOS3/LEP",13]
["GO:0110148","biomineralization","13/267","163/18866",5.83054591103923e-07,3.70852429730177e-06,1.32834026186465e-06,"IGF1/FGFR2/FGFR3/PTGS2/P2RX7/HIF1A/GATA1/TGFB1/COL1A1/PTK2B/ATF4/NOS3/LEP",13]
["GO:0001676","long-chain fatty acid metabolic process","11/267","113/18866",6.03520977956535e-07,3.83381710297326e-06,1.37321834946853e-06,"ACSL4/PTGS2/CYP2D6/MAPK3/CYP2E1/GSTM1/CYP1A2/CYP3A4/CYP2C19/CYP2B6/GPX1",11]
["GO:0032370","positive regulation of lipid transport","9/267","70/18866",6.0931867929837e-07,3.86082254535122e-06,1.38289131195289e-06,"PON1/TAC1/P2RX7/SIRT1/OXT/IL1B/APOE/ADIPOQ/PTCH1",9]
["GO:0050795","regulation of behavior","9/267","70/18866",6.0931867929837e-07,3.86082254535122e-06,1.38289131195289e-06,"HDAC4/CNR1/APOE/DRD2/PENK/CCK/HDAC2/MTOR/INS",9]
["GO:0001893","maternal placenta development","7/267","36/18866",6.1787580240179e-07,3.91008096500905e-06,1.40053497202407e-06,"PTGS2/MAPK1/MAPK3/VDR/LIF/MEN1/AKT1",7]
["GO:0046661","male sex differentiation","13/267","164/18866",6.25358267090538e-07,3.93460406841245e-06,1.4093187962585e-06,"ATRX/BAX/ESR1/GATA1/SFRP1/FGF8/PDGFRB/SRD5A1/SHH/CTNNB1/AR/BCL2L1/BCL2",13]
["GO:0002052","positive regulation of neuroblast proliferation","6/267","23/18866",6.26479117642279e-07,3.93460406841245e-06,1.4093187962585e-06,"PAX6/HIF1A/VEGFA/DRD2/SHH/CTNNB1",6]
["GO:0035162","embryonic hemopoiesis","6/267","23/18866",6.26479117642279e-07,3.93460406841245e-06,1.4093187962585e-06,"HIF1A/GATA1/VEGFA/TPO/KMT2A/ATF4",6]
["GO:0051043","regulation of membrane protein ectodomain proteolysis","6/267","23/18866",6.26479117642279e-07,3.93460406841245e-06,1.4093187962585e-06,"TNFRSF1B/IFNG/IL1B/APOE/IL10/TNF",6]
["GO:0072215","regulation of metanephros development","6/267","23/18866",6.26479117642279e-07,3.93460406841245e-06,1.4093187962585e-06,"PDGFRB/LIF/RET/CTNNB1/GDNF/ADIPOQ",6]
["GO:1901522","positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus","6/267","23/18866",6.26479117642279e-07,3.93460406841245e-06,1.4093187962585e-06,"XBP1/EP300/HIF1A/VEGFA/ATF4/TP53",6]
["GO:0098754","detoxification","12/267","138/18866",6.32353178356489e-07,3.96650680845974e-06,1.42074590059201e-06,"PTGS2/SOD2/TPO/APOE/GSTM1/SOD1/ALB/NOS3/NQO1/TNF/GPX1/HP",12]
["GO:0010883","regulation of lipid storage","8/267","52/18866",6.36346462426034e-07,3.98155123670826e-06,1.42613459921097e-06,"APOB/SIRT1/CRP/IL6/FTO/LEP/LPL/TNF",8]
["GO:1990089","response to nerve growth factor","8/267","52/18866",6.36346462426034e-07,3.98155123670826e-06,1.42613459921097e-06,"TAC1/CREB1/NGF/AKT1/NTRK2/PTEN/BDNF/MAPT",8]
["GO:0001843","neural tube closure","10/267","91/18866",6.39387850623122e-07,3.99557389006414e-06,1.43115731270494e-06,"PRKACA/TSC2/SFRP1/TGFB1/KDM6A/DVL3/MTHFR/FZD2/MED12/PTCH1",10]
["GO:0010623","programmed cell death involved in cell development","5/267","13/18866",6.41499108755455e-07,3.99875786518849e-06,1.4322977669696e-06,"BAX/IL1A/IL1B/BCL2/BDNF",5]
["GO:0035641","locomotory exploration behavior","5/267","13/18866",6.41499108755455e-07,3.99875786518849e-06,1.4322977669696e-06,"APOE/PRKCE/PENK/LRRK2/DPP4",5]
["GO:0030336","negative regulation of cell migration","19/267","350/18866",6.43655627368666e-07,4.00719769008946e-06,1.43532079131036e-06,"SFRP1/TGFB1/CCL2/PPARGC1A/SRF/DUSP1/APOE/AKT1/GNRH1/DRD2/SHH/MECP2/BCL2/PTEN/ERBB4/ADIPOQ/NF1/DPP4/TNF",19]
["GO:0043122","regulation of I-kappaB kinase/NF-kappaB signaling","16/267","252/18866",6.53005088633479e-07,4.06034172795387e-06,1.45435622414404e-06,"TNFRSF1A/ESR1/SIRT1/IL1B/AKT1/PLK2/S100B/SQSTM1/CTNNB1/FADD/PRKCE/ADIPOQ/PRKN/HLA-DRB1/TLE1/TNF",16]
["GO:0019722","calcium-mediated signaling","15/267","222/18866",6.70746234971044e-07,4.15513145311467e-06,1.48830854540395e-06,"IGF1/ERBB3/HDAC4/PRKACA/GSK3B/P2RX7/PTK2B/CDH13/CXCL8/ATP2A2/MAPT/LRRK2/MTOR/DMD/TNF",15]
["GO:0032388","positive regulation of intracellular transport","15/267","222/18866",6.70746234971044e-07,4.15513145311467e-06,1.48830854540395e-06,"PRKACA/PTGS2/GSK3B/MAPK1/TGFB1/MAPK8/IFNG/IL1B/TP53/PIK3R1/SHH/CDK5/BCL2/LEP/PRKN",15]
["GO:0097529","myeloid leukocyte migration","15/267","222/18866",6.70746234971044e-07,4.15513145311467e-06,1.48830854540395e-06,"MAPK1/MAPK3/CCL2/IL17A/VEGFA/DUSP1/PTK2B/IL1B/RAC1/IL6/IL6R/CXCL8/CSF1R/DPP4/AGER",15]
["GO:0042982","amyloid precursor protein metabolic process","9/267","71/18866",6.89221110951571e-07,4.26428873231871e-06,1.52740711864178e-06,"IGF1/DLG1/IFNG/APOE/ADAM10/NTRK2/PAWR/AGER/TNF",9]
["GO:0060606","tube closure","10/267","92/18866",7.08520058020606e-07,4.37826813081298e-06,1.56823290591064e-06,"PRKACA/TSC2/SFRP1/TGFB1/KDM6A/DVL3/MTHFR/FZD2/MED12/PTCH1",10]
["GO:0006475","internal protein amino acid acetylation","13/267","166/18866",7.18277118725195e-07,4.4330749737885e-06,1.5878639317079e-06,"CREBBP/BRCA1/SIRT1/SMARCB1/EP300/MAPK3/PPARGC1A/KMT2A/IL1B/LIF/BRCA2/MECP2/MAPT",13]
["GO:0060969","negative regulation of gene silencing","7/267","37/18866",7.52894937625759e-07,4.64099311551286e-06,1.66233723070327e-06,"ESR1/TGFB1/IL6/TP53/LIN28B/TNF/NEAT1",7]
["GO:0051702","interaction with symbiont","10/267","93/18866",7.84099550655824e-07,4.81572265432711e-06,1.72492284771349e-06,"REST/SMARCB1/EP300/APOE/CRP/JUN/F2/CSF1R/PRKN/GPX1",10]
["GO:0072080","nephron tubule development","10/267","93/18866",7.84099550655824e-07,4.81572265432711e-06,1.72492284771349e-06,"DLG1/FGF8/VEGFA/LIF/SHH/CTNNB1/GDNF/BCL2/PTCH1/DLL1",10]
["GO:0030518","intracellular steroid hormone receptor signaling pathway","11/267","116/18866",7.86063281249068e-07,4.81572265432711e-06,1.72492284771349e-06,"BRCA1/ESR1/HDAC6/SIRT1/EP300/SFRP1/NR3C1/ESR2/NR3C2/KMT2D/AR",11]
["GO:0032640","tumor necrosis factor production","11/267","116/18866",7.86063281249068e-07,4.81572265432711e-06,1.72492284771349e-06,"IGF1/TSPO/POMC/IL10/PIK3R1/FADD/LEP/PTPN11/ADIPOQ/HDAC2/MC1R",11]
["GO:0046620","regulation of organ growth","11/267","116/18866",7.86063281249068e-07,4.81572265432711e-06,1.72492284771349e-06,"IGF1/FGFR2/FGFR1/MAPK1/FGF8/DUSP6/SOD1/AKT1/PTEN/ERBB4/MTOR",11]
["GO:0006816","calcium ion transport","21/267","426/18866",7.92315037643729e-07,4.84807473401365e-06,1.73651089906694e-06,"PRKACA/PTGS2/BAX/P2RX7/TSPO/HTR2A/CCL2/VDR/OPRM1/PDGFRB/PTK2B/DRD2/NOS3/CDK5/CTNNB1/PRKCE/CHD7/BCL2/ATP2A2/F2/DMD",21]
["GO:0045665","negative regulation of neuron differentiation","15/267","225/18866",7.95176387275437e-07,4.85962754181916e-06,1.74064894927651e-06,"CD38/PAX6/NGFR/NOTCH3/GSK3B/REST/APOE/PLK2/SHH/CDK5/PTEN/DCC/LRRK2/HDAC2/DLL1",15]
["GO:0003002","regionalization","19/267","355/18866",7.96860205804437e-07,4.86396455694566e-06,1.74220240594742e-06,"PAX6/FGFR2/PRKACA/GLI2/FGFR1/EP300/SFRP1/FGF8/SRF/TP53/KDM6A/SHH/OTX2/CTNNB1/GDNF/AR/MED12/PTCH1/DLL1",19]
["GO:0050728","negative regulation of inflammatory response","14/267","196/18866",8.18029072783077e-07,4.98708078193639e-06,1.78630087354084e-06,"IGF1/TNFRSF1B/GRN/TNFRSF1A/IL2/APOE/IL10/SOD1/F2/ADIPOQ/HLA-DRB1/AGER/GPX1/INS",14]
["GO:0042738","exogenous drug catabolic process","6/267","24/18866",8.25432391433406e-07,5.00167952721723e-06,1.7915299349072e-06,"CYP2D6/CYP2E1/CYP1A2/CYP3A4/CYP2C19/CYP2B6",6]
["GO:0045821","positive regulation of glycolytic process","6/267","24/18866",8.25432391433406e-07,5.00167952721723e-06,1.7915299349072e-06,"IGF1/P2RX7/HIF1A/HTR2A/IFNG/INS",6]
["GO:0048745","smooth muscle tissue development","6/267","24/18866",8.25432391433406e-07,5.00167952721723e-06,1.7915299349072e-06,"DLG1/SRF/PDGFRB/SHH/PTCH1/NF1",6]
["GO:0051882","mitochondrial depolarization","6/267","24/18866",8.25432391433406e-07,5.00167952721723e-06,1.7915299349072e-06,"GCLC/P2RX7/TSPO/BCL2/CCK/LRRK2",6]
["GO:0090335","regulation of brown fat cell differentiation","6/267","24/18866",8.25432391433406e-07,5.00167952721723e-06,1.7915299349072e-06,"PTGS2/SIRT1/FTO/LEP/MTOR/INS",6]
["GO:0018107","peptidyl-threonine phosphorylation","11/267","117/18866",8.56892321014334e-07,5.17737547820166e-06,1.85446170690854e-06,"PRKACA/GSK3B/MAPK1/TGFB1/MAPK8/AKT1/CDK5/MAP2K1/BCL2/LRRK2/MTOR",11]
["GO:0030282","bone mineralization","11/267","117/18866",8.56892321014334e-07,5.17737547820166e-06,1.85446170690854e-06,"IGF1/FGFR2/FGFR3/PTGS2/P2RX7/HIF1A/GATA1/TGFB1/PTK2B/ATF4/LEP",11]
["GO:0031050","dsRNA processing","8/267","54/18866",8.58575384728815e-07,5.17737547820166e-06,1.85446170690854e-06,"ESR1/TGFB1/MAP2K2/IL6/TP53/MAP2K1/LIN28B/TNF",8]
["GO:0070918","production of small RNA involved in gene silencing by RNA","8/267","54/18866",8.58575384728815e-07,5.17737547820166e-06,1.85446170690854e-06,"ESR1/TGFB1/MAP2K2/IL6/TP53/MAP2K1/LIN28B/TNF",8]
["GO:0045778","positive regulation of ossification","10/267","94/18866",8.66631314462975e-07,5.21336163025739e-06,1.86735143091008e-06,"TAC1/IGF1/GNAS/P2RX7/OXT/TGFB1/IL6/IL6R/CTNNB1/PTPN11",10]
["GO:0051591","response to cAMP","10/267","94/18866",8.66631314462975e-07,5.21336163025739e-06,1.86735143091008e-06,"OXT/COL1A1/DUSP1/PTK2B/LDHA/SLC6A3/SRD5A1/FOS/ADIPOQ/PENK",10]
["GO:0010517","regulation of phospholipase activity","9/267","73/18866",8.76576428464384e-07,5.26051214822436e-06,1.88424007080085e-06,"FGFR2/FGFR3/FGFR1/ESR1/HTR2A/PDGFRB/NTRK2/EDNRA/BDNF",9]
["GO:0051145","smooth muscle cell differentiation","9/267","73/18866",8.76576428464384e-07,5.26051214822436e-06,1.88424007080085e-06,"FGFR2/SIRT1/SOD2/SRF/VEGFA/DNMT1/SHH/CTNNB1/MECP2",9]
["GO:0055002","striated muscle cell development","13/267","169/18866",8.80821890504418e-07,5.27964429686501e-06,1.89109293228913e-06,"IGF1/HDAC9/HDAC4/PRKAR1A/SRF/VEGFA/PDGFRB/PDLIM5/BCL2/NEB/MTOR/DMD/GPX1",13]
["GO:0010661","positive regulation of muscle cell apoptotic process","7/267","38/18866",9.11821545197532e-07,5.43284603242396e-06,1.94596759865671e-06,"IFNG/SOD2/MFN2/ATF4/TP53/CDKN2A/PTEN",7]
["GO:0010742","macrophage derived foam cell differentiation","7/267","38/18866",9.11821545197532e-07,5.43284603242396e-06,1.94596759865671e-06,"APOB/EP300/TGFB1/CRP/IL18/LPL/ADIPOQ",7]
["GO:0032094","response to food","7/267","38/18866",9.11821545197532e-07,5.43284603242396e-06,1.94596759865671e-06,"OXT/OPRM1/NPY/AKT1/LEP/CCK/MTOR",7]
["GO:0090077","foam cell differentiation","7/267","38/18866",9.11821545197532e-07,5.43284603242396e-06,1.94596759865671e-06,"APOB/EP300/TGFB1/CRP/IL18/LPL/ADIPOQ",7]
["GO:2000144","positive regulation of DNA-templated transcription, initiation","7/267","38/18866",9.11821545197532e-07,5.43284603242396e-06,1.94596759865671e-06,"ESR1/SRF/CREB1/TP53/CTNNB1/JUN/MED12",7]
["GO:0032409","regulation of transporter activity","17/267","291/18866",9.29831250583977e-07,5.53354878923218e-06,1.98203788312173e-06,"PON1/PRKACA/DLG1/ABCB1/CCL2/PPARGC1A/IFNG/OPRM1/KMT2A/PTK2B/DRD2/CDK5/PRKCE/BCL2/PTEN/DMD/INS",17]
["GO:0008543","fibroblast growth factor receptor signaling pathway","11/267","118/18866",9.33283409579979e-07,5.54088473725664e-06,1.98466551458337e-06,"NGFR/FGFR2/FGFR3/FGFR1/MAPK1/MAPK3/FGF8/FGF17/OTX2/CTNNB1/PTPN11",11]
["GO:0021987","cerebral cortex development","11/267","118/18866",9.33283409579979e-07,5.54088473725664e-06,1.98466551458337e-06,"PAX6/GSK3B/BAX/HIF1A/NPY/SRD5A1/NTRK2/CDK5/CTNNB1/PAX5/NF1",11]
["GO:0031589","cell-substrate adhesion","19/267","359/18866",9.42585613151945e-07,5.58946551837015e-06,2.00206645423822e-06,"GSK3B/OLFM4/SFRP1/COL1A1/SRF/VEGFA/PTK2B/MEN1/RAC1/CDH13/PIK3R1/CDKN2A/CDK5/CTNNB1/PRKCE/BCL2/PTEN/NF1/L1CAM",19]
["GO:0007589","body fluid secretion","10/267","95/18866",9.56652188510431e-07,5.65273890796755e-06,2.02473007571376e-06,"TAC1/XBP1/HIF1A/VDR/VEGFA/CREB1/SLC6A3/PRKCE/PRL/ERBB4",10]
["GO:0050709","negative regulation of protein secretion","10/267","95/18866",9.56652188510431e-07,5.65273890796755e-06,2.02473007571376e-06,"HDAC9/REST/SFRP1/OPRM1/IL1B/APOE/DRD2/PTPN11/PRKN/INS",10]
["GO:0061326","renal tubule development","10/267","95/18866",9.56652188510431e-07,5.65273890796755e-06,2.02473007571376e-06,"DLG1/FGF8/VEGFA/LIF/SHH/CTNNB1/GDNF/BCL2/PTCH1/DLL1",10]
["GO:0006801","superoxide metabolic process","9/267","74/18866",9.85728056122131e-07,5.80767773576921e-06,2.08022694363095e-06,"NOS2/TGFB1/SOD2/CRP/SOD1/NOS3/NQO1/MAPT/TNF",9]
["GO:0032310","prostaglandin secretion","5/267","14/18866",9.86363052259621e-07,5.80767773576921e-06,2.08022694363095e-06,"NOS2/P2RX7/OXT/IL1B/LEP",5]
["GO:0072216","positive regulation of metanephros development","5/267","14/18866",9.86363052259621e-07,5.80767773576921e-06,2.08022694363095e-06,"PDGFRB/LIF/RET/GDNF/ADIPOQ",5]
["GO:0035065","regulation of histone acetylation","8/267","55/18866",9.92514844303543e-07,5.83701603958491e-06,2.09073550365349e-06,"BRCA1/SIRT1/SMARCB1/MAPK3/PPARGC1A/KMT2A/IL1B/LIF",8]
["GO:0006720","isoprenoid metabolic process","12/267","144/18866",9.98456901099881e-07,5.84442591698911e-06,2.09338961555957e-06,"APOB/CYP2D6/TTR/APOE/CYP2E1/CYP1A2/SRD5A1/CYP3A4/CYP2C19/LPL/GPC6/ADH1C",12]
["GO:0060078","regulation of postsynaptic membrane potential","12/267","144/18866",9.98456901099881e-07,5.84442591698911e-06,2.09338961555957e-06,"GABRA3/GSK3B/P2RX7/OPRM1/PTK2B/AKT1/DRD2/CDK5/MECP2/PTEN/BDNF/LRRK2",12]
["GO:0106106","cold-induced thermogenesis","12/267","144/18866",9.98456901099881e-07,5.84442591698911e-06,2.09338961555957e-06,"GNAS/OXT/PPARGC1A/VEGFA/MFN2/ATF4/PER2/KDM6B/IL18/LEP/EHMT1/ADIPOQ",12]
["GO:0120161","regulation of cold-induced thermogenesis","12/267","144/18866",9.98456901099881e-07,5.84442591698911e-06,2.09338961555957e-06,"GNAS/OXT/PPARGC1A/VEGFA/MFN2/ATF4/PER2/KDM6B/IL18/LEP/EHMT1/ADIPOQ",12]
["GO:1901888","regulation of cell junction assembly","14/267","200/18866",1.04231411042525e-06,6.09399807184224e-06,2.18278278517503e-06,"PRKACA/ADNP/OXT/SFRP1/VEGFA/IL1B/RAC1/NTRK2/ACE/PDLIM5/PTEN/BDNF/GPC6/TNF",14]
["GO:0007160","cell-matrix adhesion","15/267","230/18866",1.04933099445119e-06,6.12784755005238e-06,2.19490718322261e-06,"GSK3B/SFRP1/SRF/VEGFA/PTK2B/RAC1/CDH13/PIK3R1/CDKN2A/CDK5/CTNNB1/BCL2/PTEN/NF1/L1CAM",15]
["GO:0002690","positive regulation of leukocyte chemotaxis","10/267","96/18866",1.05473236283976e-06,6.15219472857352e-06,2.20362799368514e-06,"MAPK1/MAPK3/VEGFA/PTK2B/RAC1/IL6/ADAM10/IL6R/CXCL8/CSF1R",10]
["GO:0000423","mitophagy","6/267","25/18866",1.07326064390273e-06,6.23115162210038e-06,2.23190922153089e-06,"HDAC6/TSC2/MFN2/TP53/SQSTM1/PRKN",6]
["GO:0046697","decidualization","6/267","25/18866",1.07326064390273e-06,6.23115162210038e-06,2.23190922153089e-06,"PTGS2/MAPK1/MAPK3/VDR/LIF/MEN1",6]
["GO:0060571","morphogenesis of an epithelial fold","6/267","25/18866",1.07326064390273e-06,6.23115162210038e-06,2.23190922153089e-06,"FGFR2/GLI2/HIF1A/SHH/CTNNB1/AR",6]
["GO:2000679","positive regulation of transcription regulatory region DNA binding","6/267","25/18866",1.07326064390273e-06,6.23115162210038e-06,2.23190922153089e-06,"PAX6/IGF1/EP300/TGFB1/IFNG/CTNNB1",6]
["GO:0018394","peptidyl-lysine acetylation","13/267","172/18866",1.07540015107167e-06,6.23632166585462e-06,2.23376105711934e-06,"CREBBP/BRCA1/SIRT1/SMARCB1/EP300/MAPK3/PPARGC1A/KMT2A/IL1B/LIF/BRCA2/MECP2/HDAC2",13]
["GO:0001662","behavioral fear response","7/267","39/18866",1.09794074180119e-06,6.34492838404324e-06,2.27266242729072e-06,"APOE/MECP2/BCL2/BDNF/PENK/CCK/DPP4",7]
["GO:0014037","Schwann cell differentiation","7/267","39/18866",1.09794074180119e-06,6.34492838404324e-06,2.27266242729072e-06,"ERBB3/SOD1/AKT1/NTRK2/CDK5/MED12/NF1",7]
["GO:0046326","positive regulation of glucose import","7/267","39/18866",1.09794074180119e-06,6.34492838404324e-06,2.27266242729072e-06,"IGF1/AKT1/PIK3R1/PRKCI/PTPN11/ADIPOQ/INS",7]
["GO:0006304","DNA modification","11/267","120/18866",1.10425810669824e-06,6.36452170359276e-06,2.2796804735902e-06,"BRCA1/ATRX/GNAS/KMT2A/PIK3CA/DNMT1/PRMT7/FTO/MECP2/FOS/EHMT1",11]
["GO:0046323","glucose import","9/267","75/18866",1.10642996970128e-06,6.36452170359276e-06,2.2796804735902e-06,"IGF1/AKT1/PIK3R1/PRKCI/LEP/PTPN11/ADIPOQ/TNF/INS",9]
["GO:0048844","artery morphogenesis","9/267","75/18866",1.10642996970128e-06,6.36452170359276e-06,2.2796804735902e-06,"NOTCH3/APOB/FGF8/SRF/VEGFA/PDGFRB/APOE/CHD7/NF1",9]
["GO:0072088","nephron epithelium morphogenesis","9/267","75/18866",1.10642996970128e-06,6.36452170359276e-06,2.2796804735902e-06,"DLG1/FGF8/VEGFA/LIF/SHH/CTNNB1/GDNF/BCL2/PTCH1",9]
["GO:0010332","response to gamma radiation","8/267","56/18866",1.14387405231532e-06,6.57233963545502e-06,2.35411787884893e-06,"BAX/MEN1/BRCA2/POLG/TP53/BCL2L1/BCL2/GPX1",8]
["GO:0030595","leukocyte chemotaxis","15/267","232/18866",1.16994765222992e-06,6.71442370986663e-06,2.40501035830445e-06,"MAPK1/MAPK3/CCL2/VEGFA/DUSP1/PTK2B/IL1B/RAC1/IL6/IL10/ADAM10/IL6R/CXCL8/CSF1R/DPP4",15]
["GO:0032612","interleukin-1 production","11/267","121/18866",1.19964656562465e-06,6.876963607536e-06,2.46322982052846e-06,"IGF1/P2RX7/IFNG/IL17A/IL1B/IL6/IL10/LPL/HDAC2/AGER/TNF",11]
["GO:2000146","negative regulation of cell motility","19/267","365/18866",1.20701853499164e-06,6.91128846928126e-06,2.4755244941463e-06,"SFRP1/TGFB1/CCL2/PPARGC1A/SRF/DUSP1/APOE/AKT1/GNRH1/DRD2/SHH/MECP2/BCL2/PTEN/ERBB4/ADIPOQ/NF1/DPP4/TNF",19]
["GO:0060193","positive regulation of lipase activity","9/267","76/18866",1.23968893880701e-06,7.08211312524414e-06,2.53671143807431e-06,"FGFR2/FGFR3/FGFR1/ESR1/HTR2A/PDGFRB/NTRK2/EDNRA/BDNF",9]
["GO:0071229","cellular response to acid chemical","9/267","76/18866",1.23968893880701e-06,7.08211312524414e-06,2.53671143807431e-06,"GCLC/XBP1/COL1A1/VEGFA/DNMT1/NTRK2/BCL2L1/MTOR/TNF",9]
["GO:0055123","digestive system development","12/267","147/18866",1.24390467190512e-06,7.09807545922546e-06,2.5424289173736e-06,"FGFR2/GLI2/XBP1/HIF1A/SFRP1/NPY/SHH/RET/CTNNB1/CXCL8/BCL2/TNF",12]
["GO:0031330","negative regulation of cellular catabolic process","16/267","265/18866",1.27016498630155e-06,7.23965042991281e-06,2.5931390431703e-06,"FUS/TSPO/TSC2/CNR1/PIK3CA/IL10/TP53/AKT1/SHH/GDNF/BCL2/LEP/LRRK2/MTOR/INS/HP",16]
["GO:0045833","negative regulation of lipid metabolic process","10/267","98/18866",1.27752741728164e-06,7.27331173829788e-06,2.60519604148294e-06,"BRCA1/REST/SIRT1/CNR1/IL1B/APOE/SOD1/AKT1/TNF/INS",10]
["GO:0050432","catecholamine secretion","8/267","57/18866",1.31447416883855e-06,7.4688359554841e-06,2.67523001430792e-06,"OXT/HTR2A/CNR1/DRD2/GDNF/MECP2/SNCG/PRKN",8]
["GO:0042307","positive regulation of protein import into nucleus","7/267","40/18866",1.31486216800932e-06,7.4688359554841e-06,2.67523001430792e-06,"PTGS2/MAPK1/TGFB1/IFNG/PIK3R1/SHH/LEP",7]
["GO:0031644","regulation of nervous system process","12/267","148/18866",1.33684281728729e-06,7.58506384854025e-06,2.71686118010897e-06,"TNFRSF1B/COMT/OXT/OPRM1/PTK2B/IL10/S100B/NOS3/PTEN/CCK/LRRK2/MTOR",12]
["GO:0042737","drug catabolic process","6/267","26/18866",1.37875457541378e-06,7.79628719710192e-06,2.79251835683139e-06,"CYP2D6/CYP2E1/CYP1A2/CYP3A4/CYP2C19/CYP2B6",6]
["GO:0060740","prostate gland epithelium morphogenesis","6/267","26/18866",1.37875457541378e-06,7.79628719710192e-06,2.79251835683139e-06,"FGFR2/GLI2/ESR1/SFRP1/SHH/AR",6]
["GO:1903649","regulation of cytoplasmic transport","6/267","26/18866",1.37875457541378e-06,7.79628719710192e-06,2.79251835683139e-06,"MAPK1/MAPK3/MAP2K2/MAP2K1/PRKN/LRRK2",6]
["GO:0034349","glial cell apoptotic process","5/267","15/18866",1.46246261695511e-06,8.23232902644517e-06,2.94870229182547e-06,"CCL2/TP53/PRKCI/CDK5/DLL1",5]
["GO:0045346","regulation of MHC class II biosynthetic process","5/267","15/18866",1.46246261695511e-06,8.23232902644517e-06,2.94870229182547e-06,"SIRT1/XBP1/IFNG/IL10/HDAC2",5]
["GO:0051044","positive regulation of membrane protein ectodomain proteolysis","5/267","15/18866",1.46246261695511e-06,8.23232902644517e-06,2.94870229182547e-06,"TNFRSF1B/IFNG/IL1B/APOE/TNF",5]
["GO:0090594","inflammatory response to wounding","5/267","15/18866",1.46246261695511e-06,8.23232902644517e-06,2.94870229182547e-06,"GRN/HIF1A/TGFB1/IL1A/AGER",5]
["GO:0019369","arachidonic acid metabolic process","8/267","58/18866",1.50628025444207e-06,8.46943390814105e-06,3.03362986284623e-06,"PTGS2/CYP2D6/MAPK3/CYP2E1/CYP1A2/CYP2C19/CYP2B6/GPX1",8]
["GO:0070301","cellular response to hydrogen peroxide","10/267","100/18866",1.54030466424184e-06,8.64711896899171e-06,3.09727410549863e-06,"HDAC6/SIRT1/PDGFRB/KDM6B/IL6/IL10/PAWR/NQO1/LRRK2/HDAC2",10]
["GO:0006606","protein import into nucleus","12/267","150/18866",1.54134505956391e-06,8.64711896899171e-06,3.09727410549863e-06,"PTGS2/MAPK1/TSC2/TGFB1/IFNG/TP53/AKT1/PIK3R1/SHH/LEP/LRRK2/NF1",12]
["GO:0031348","negative regulation of defense response","16/267","269/18866",1.54566363040666e-06,8.66161448554484e-06,3.10246619181395e-06,"IGF1/TNFRSF1B/GRN/TNFRSF1A/IL2/APOE/IL10/SOD1/DRD2/F2/ADIPOQ/CCK/HLA-DRB1/AGER/GPX1/INS",16]
["GO:0007212","dopamine receptor signaling pathway","7/267","41/18866",1.56653933531734e-06,8.74913971055873e-06,3.13381647321814e-06,"GSK3B/GNAS/OPRM1/GNAL/DRD2/ALK/LRRK2",7]
["GO:0007618","mating","7/267","41/18866",1.56653933531734e-06,8.74913971055873e-06,3.13381647321814e-06,"TAC1/HDAC4/OXT/CNR1/PPP1R1B/PTEN/HDAC2",7]
["GO:0042596","fear response","7/267","41/18866",1.56653933531734e-06,8.74913971055873e-06,3.13381647321814e-06,"APOE/MECP2/BCL2/BDNF/PENK/CCK/DPP4",7]
["GO:0008643","carbohydrate transport","12/267","151/18866",1.65361055817835e-06,9.22511454411676e-06,3.30430383810058e-06,"IGF1/IL1B/AKT1/PIK3R1/EDNRA/BRAF/PRKCI/LEP/PTPN11/ADIPOQ/TNF/INS",12]
["GO:0001952","regulation of cell-matrix adhesion","11/267","125/18866",1.65763556577109e-06,9.23724819184717e-06,3.30864993684808e-06,"GSK3B/SFRP1/VEGFA/PTK2B/RAC1/CDH13/PIK3R1/CDKN2A/BCL2/PTEN/NF1",11]
["GO:0048469","cell maturation","13/267","179/18866",1.68563649060537e-06,9.35709137746749e-06,3.35157604864015e-06,"PRKACA/FGFR1/XBP1/HIF1A/VEGFA/PTK2B/BRCA2/RET/CTNNB1/MECP2/BCL2/LRRK2/MTOR",13]
["GO:0015908","fatty acid transport","10/267","101/18866",1.68851178271544e-06,9.35709137746749e-06,3.35157604864015e-06,"NOS2/ACSL4/P2RX7/OXT/IL1B/APOE/AKT1/DRD2/ACE/LEP",10]
["GO:0019217","regulation of fatty acid metabolic process","10/267","101/18866",1.68851178271544e-06,9.35709137746749e-06,3.35157604864015e-06,"BRCA1/PTGS2/SIRT1/PPARGC1A/CNR1/IL1B/AKT1/ADIPOQ/MTOR/INS",10]
["GO:0042102","positive regulation of T cell proliferation","10/267","101/18866",1.68851178271544e-06,9.35709137746749e-06,3.35157604864015e-06,"IGF1/IL2/IL1A/IL1B/IL6/IL18/SHH/FADD/LEP/AGER",10]
["GO:0042116","macrophage activation","10/267","101/18866",1.68851178271544e-06,9.35709137746749e-06,3.35157604864015e-06,"GRN/IFNG/IL6/IL10/PRKCE/JUN/MAPT/LRRK2/AGER/TNF",10]
["GO:0001658","branching involved in ureteric bud morphogenesis","8/267","59/18866",1.72140882170574e-06,9.4906940929579e-06,3.39943062686403e-06,"DLG1/FGF8/VEGFA/SHH/CTNNB1/GDNF/BCL2/PTCH1",8]
["GO:0042306","regulation of protein import into nucleus","8/267","59/18866",1.72140882170574e-06,9.4906940929579e-06,3.39943062686403e-06,"PTGS2/MAPK1/TGFB1/IFNG/PIK3R1/SHH/LEP/NF1",8]
["GO:0050707","regulation of cytokine secretion","8/267","59/18866",1.72140882170574e-06,9.4906940929579e-06,3.39943062686403e-06,"HDAC9/P2RX7/IFNG/IL1A/IL10/DRD2/TNF/INS",8]
["GO:0000422","autophagy of mitochondrion","9/267","79/18866",1.72592634416298e-06,9.4906940929579e-06,3.39943062686403e-06,"HDAC6/TSPO/HIF1A/TSC2/PPARGC1A/MFN2/TP53/SQSTM1/PRKN",9]
["GO:0050672","negative regulation of lymphocyte proliferation","9/267","79/18866",1.72592634416298e-06,9.4906940929579e-06,3.39943062686403e-06,"DLG1/PRKAR1A/IL2/IDO1/IL10/GNRH1/SHH/PAWR/HLA-DRB1",9]
["GO:0061726","mitochondrion disassembly","9/267","79/18866",1.72592634416298e-06,9.4906940929579e-06,3.39943062686403e-06,"HDAC6/TSPO/HIF1A/TSC2/PPARGC1A/MFN2/TP53/SQSTM1/PRKN",9]
["GO:1900034","regulation of cellular response to heat","9/267","79/18866",1.72592634416298e-06,9.4906940929579e-06,3.39943062686403e-06,"CREBBP/GSK3B/SIRT1/MAPK1/EP300/MAPK3/BAG1/MAPT/MTOR",9]
["GO:0045672","positive regulation of osteoclast differentiation","6/267","27/18866",1.75174533871411e-06,9.6114994243951e-06,3.4427013655006e-06,"GNAS/IFNG/IL17A/CREB1/FOS/TNF",6]
["GO:1903203","regulation of oxidative stress-induced neuron death","6/267","27/18866",1.75174533871411e-06,9.6114994243951e-06,3.4427013655006e-06,"REST/HIF1A/ATF4/IL10/CTNNB1/PRKN",6]
["GO:0018210","peptidyl-threonine modification","11/267","126/18866",1.79371496600484e-06,9.83097565890466e-06,3.52131460770953e-06,"PRKACA/GSK3B/MAPK1/TGFB1/MAPK8/AKT1/CDK5/MAP2K1/BCL2/LRRK2/MTOR",11]
["GO:1990778","protein localization to cell periphery","18/267","340/18866",1.8257227082569e-06,9.99543144991965e-06,3.58022031547609e-06,"TNFRSF1A/DLG1/TGFB1/IFNG/ADAM10/AKT1/PIK3R1/SQSTM1/PRKCI/CDK5/AR/PRKCE/BCL2L1/ADIPOQ/GPC6/PTCH1/TNF/INS",18]
["GO:0001504","neurotransmitter uptake","7/267","42/18866",1.85728925154429e-06,1.01460013489722e-05,3.63415229572008e-06,"PER2/GLUL/TOR1A/SLC6A3/DRD2/GDNF/PRKN",7]
["GO:1904591","positive regulation of protein import","7/267","42/18866",1.85728925154429e-06,1.01460013489722e-05,3.63415229572008e-06,"PTGS2/MAPK1/TGFB1/IFNG/PIK3R1/SHH/LEP",7]
["GO:0006110","regulation of glycolytic process","9/267","80/18866",1.92090549889164e-06,1.04820559081595e-05,3.75452222331539e-06,"IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/INS",9]
["GO:0030326","embryonic limb morphogenesis","11/267","127/18866",1.93950616769124e-06,1.05604736044519e-05,3.78261031843818e-06,"CREBBP/GLI2/FGFR1/BAX/GNAS/FGF8/SHH/CTNNB1/CHD7/PTCH1/HDAC2",11]
["GO:0035113","embryonic appendage morphogenesis","11/267","127/18866",1.93950616769124e-06,1.05604736044519e-05,3.78261031843818e-06,"CREBBP/GLI2/FGFR1/BAX/GNAS/FGF8/SHH/CTNNB1/CHD7/PTCH1/HDAC2",11]
["GO:0032732","positive regulation of interleukin-1 production","8/267","60/18866",1.96213555118741e-06,1.06488508772595e-05,3.81426579115265e-06,"P2RX7/IFNG/IL17A/IL6/LPL/HDAC2/AGER/TNF",8]
["GO:0043388","positive regulation of DNA binding","8/267","60/18866",1.96213555118741e-06,1.06488508772595e-05,3.81426579115265e-06,"PAX6/IGF1/EP300/TGFB1/IFNG/NGF/CTNNB1/PRKN",8]
["GO:1903428","positive regulation of reactive oxygen species biosynthetic process","8/267","60/18866",1.96213555118741e-06,1.06488508772595e-05,3.81426579115265e-06,"HDAC4/PTGS2/IFNG/PTK2B/IL1B/AKT1/MTOR/TNF",8]
["GO:1903320","regulation of protein modification by small protein conjugation or removal","15/267","242/18866",1.98102838091361e-06,1.07397119499475e-05,3.84681092539257e-06,"GCLC/BRCA1/HDAC4/TSPO/PER2/AKT1/SQSTM1/CDK5/VCP/CTNNB1/PRKCE/PTEN/PRKN/LRRK2/MTOR",15]
["GO:0042472","inner ear morphogenesis","10/267","103/18866",2.0225857107123e-06,1.09412464285878e-05,3.91899768774613e-06,"COL11A1/FGFR2/GLI2/FGFR1/FGF8/COL2A1/SOD1/HESX1/CHD7/FZD2",10]
["GO:0060079","excitatory postsynaptic potential","10/267","103/18866",2.0225857107123e-06,1.09412464285878e-05,3.91899768774613e-06,"GSK3B/P2RX7/OPRM1/PTK2B/AKT1/DRD2/CDK5/MECP2/PTEN/LRRK2",10]
["GO:0002706","regulation of lymphocyte mediated immunity","12/267","154/18866",2.03502004382017e-06,1.09965964056213e-05,3.93882325638011e-06,"TNFRSF1B/P2RX7/TGFB1/IL2/IL1B/IL6/IL10/IL18/FADD/LEP/AGER/TNF",12]
["GO:0045342","MHC class II biosynthetic process","5/267","16/18866",2.10266604055872e-06,1.1325363042621e-05,4.05658275468036e-06,"SIRT1/XBP1/IFNG/IL10/HDAC2",5]
["GO:0060572","morphogenesis of an epithelial bud","5/267","16/18866",2.10266604055872e-06,1.1325363042621e-05,4.05658275468036e-06,"FGFR2/GLI2/SHH/CTNNB1/AR",5]
["GO:0071871","response to epinephrine","5/267","16/18866",2.10266604055872e-06,1.1325363042621e-05,4.05658275468036e-06,"PRKACA/PPARGC1A/SRD5A1/ADIPOQ/PENK",5]
["GO:0034644","cellular response to UV","9/267","81/18866",2.13457370209336e-06,1.14848345846467e-05,4.11370317588092e-06,"CREBBP/PTGS2/BAX/SIRT1/EP300/ATF4/TP53/PIK3R1/MC1R",9]
["GO:1990845","adaptive thermogenesis","12/267","155/18866",2.17839490277241e-06,1.17079932718435e-05,4.1936354198746e-06,"GNAS/OXT/PPARGC1A/VEGFA/MFN2/ATF4/PER2/KDM6B/IL18/LEP/EHMT1/ADIPOQ",12]
["GO:1903146","regulation of autophagy of mitochondrion","7/267","43/18866",2.19181229051809e-06,1.17674395339321e-05,4.21492821911742e-06,"HDAC6/TSPO/HIF1A/TSC2/MFN2/TP53/PRKN",7]
["GO:0001964","startle response","6/267","28/18866",2.20316479452392e-06,1.17903556474361e-05,4.22313644259732e-06,"SLC6A3/DRD2/MECP2/PTEN/PENK/PRKN",6]
["GO:0031069","hair follicle morphogenesis","6/267","28/18866",2.20316479452392e-06,1.17903556474361e-05,4.22313644259732e-06,"NGFR/FGFR2/GLI2/SHH/CTNNB1/BCL2",6]
["GO:0060512","prostate gland morphogenesis","6/267","28/18866",2.20316479452392e-06,1.17903556474361e-05,4.22313644259732e-06,"FGFR2/GLI2/ESR1/SFRP1/SHH/AR",6]
["GO:0016236","macroautophagy","17/267","310/18866",2.20910244305468e-06,1.18094737667795e-05,4.22998427899234e-06,"PRKACA/HDAC6/SIRT1/HIF1A/MAPK3/TSC2/MAPK8/MFN2/PIK3CA/TP53/AKT1/SQSTM1/CDK5/VCP/PRKN/LRRK2/MTOR",17]
["GO:0010574","regulation of vascular endothelial growth factor production","8/267","61/18866",2.23090316559969e-06,1.19005336600847e-05,4.26260062792833e-06,"BRCA1/PTGS2/HIF1A/TGFB1/IL1A/IL1B/ATF4/IL6",8]
["GO:1903078","positive regulation of protein localization to plasma membrane","8/267","61/18866",2.23090316559969e-06,1.19005336600847e-05,4.26260062792833e-06,"DLG1/IFNG/AKT1/PIK3R1/SQSTM1/PRKCI/PRKCE/TNF",8]
["GO:0007389","pattern specification process","21/267","455/18866",2.2624782108515e-06,1.20560872004072e-05,4.31831767706195e-06,"PAX6/FGFR2/PRKACA/GLI2/FGFR1/EP300/HIF1A/SFRP1/FGF8/SRF/TP53/KDM6A/SHH/OTX2/CTNNB1/GDNF/AR/ERBB4/MED12/PTCH1/DLL1",21]
["GO:0060326","cell chemotaxis","17/267","311/18866",2.30755450725694e-06,1.22831766041939e-05,4.3996578474128e-06,"FGFR1/MAPK1/MAPK3/CCL2/VEGFA/PDGFRB/DUSP1/PTK2B/IL1B/RAC1/IL6/IL10/ADAM10/IL6R/CXCL8/CSF1R/DPP4",17]
["GO:0030902","hindbrain development","12/267","156/18866",2.33061878456041e-06,1.23927365189671e-05,4.43890063894191e-06,"GLI2/PPARGC1A/TP53/RERE/SHH/CDK5/CTNNB1/MAP2K1/MECP2/BCL2/PTPN11/DLL1",12]
["GO:0072330","monocarboxylic acid biosynthetic process","15/267","246/18866",2.42671454626795e-06,1.28899848186339e-05,4.61700785454563e-06,"BRCA1/PTGS2/SIRT1/CYP2D6/XBP1/IL1B/CYP2E1/IDO1/PER2/GSTM1/CYP27A1/CYP1A2/CYP3A4/LPL/ADIPOQ",15]
["GO:0048706","embryonic skeletal system development","11/267","130/18866",2.44116631274481e-06,1.29529685436077e-05,4.63956772230375e-06,"COL11A1/FGFR2/DLG1/GNAS/FGF8/COL1A1/COL2A1/SHH/CTNNB1/MED12/PAX5",11]
["GO:0043281","regulation of cysteine-type endopeptidase activity involved in apoptotic process","14/267","215/18866",2.4563392405659e-06,1.30196410065239e-05,4.66344884313494e-06,"NGFR/PTGS2/REST/BAX/SIRT1/VEGFA/NGF/AKT1/VCP/FADD/MAPT/CCK/TNF/GPX1",14]
["GO:0010770","positive regulation of cell morphogenesis involved in differentiation","12/267","157/18866",2.49215862539421e-06,1.31954910038105e-05,4.7264357923143e-06,"NGFR/ADNP/OLFM4/SRF/VEGFA/NGF/RAC1/NTRK2/MAP2K1/BDNF/MAPT/L1CAM",12]
["GO:0051851","modulation by host of symbiont process","8/267","62/18866",2.5303294556824e-06,1.33692433568489e-05,4.78867139538223e-06,"REST/SMARCB1/EP300/APOE/CRP/JUN/CSF1R/PRKN",8]
["GO:1904589","regulation of protein import","8/267","62/18866",2.5303294556824e-06,1.33692433568489e-05,4.78867139538223e-06,"PTGS2/MAPK1/TGFB1/IFNG/PIK3R1/SHH/LEP/NF1",8]
["GO:0032881","regulation of polysaccharide metabolic process","7/267","44/18866",2.57521227187535e-06,1.35776503415772e-05,4.86331979093671e-06,"IGF1/GSK3B/TGFB1/POMC/AKT1/MTOR/INS",7]
["GO:0044060","regulation of endocrine process","7/267","44/18866",2.57521227187535e-06,1.35776503415772e-05,4.86331979093671e-06,"TAC1/FGFR1/GNAS/POMC/IL1B/LEP/PTPN11",7]
["GO:0046928","regulation of neurotransmitter secretion","10/267","106/18866",2.63129913753128e-06,1.38476509513087e-05,4.96003014035935e-06,"GSK3B/HTR2A/CNR1/DRD2/CDK5/SNCG/ATP2A2/PRKN/LRRK2/NF1",10]
["GO:0010508","positive regulation of autophagy","11/267","131/18866",2.63196890702824e-06,1.38476509513087e-05,4.96003014035935e-06,"GSK3B/HDAC6/SIRT1/HIF1A/MAPK3/TSC2/IFNG/MFN2/PLK2/PRKN/LRRK2",11]
["GO:0072659","protein localization to plasma membrane","16/267","281/18866",2.72467525381856e-06,1.43203195182274e-05,5.12933324790884e-06,"TNFRSF1A/DLG1/TGFB1/IFNG/AKT1/PIK3R1/SQSTM1/PRKCI/CDK5/AR/PRKCE/BCL2L1/ADIPOQ/PTCH1/TNF/INS",16]
["GO:0016573","histone acetylation","12/267","159/18866",2.84515596693832e-06,1.49378167643775e-05,5.35051191303139e-06,"CREBBP/BRCA1/SIRT1/SMARCB1/EP300/MAPK3/PPARGC1A/KMT2A/IL1B/LIF/BRCA2/MECP2",12]
["GO:0046622","positive regulation of organ growth","8/267","63/18866",2.86321545099694e-06,1.50168432214577e-05,5.37881805754512e-06,"IGF1/FGFR2/FGFR1/MAPK1/FGF8/AKT1/ERBB4/MTOR",8]
["GO:0014031","mesenchymal cell development","9/267","84/18866",2.9028702732805e-06,1.52088470876071e-05,5.4475910910737e-06,"MAPK1/HIF1A/MAPK3/EDNRA/SHH/RET/GDNF/BCL2/ERBB4",9]
["GO:0015732","prostaglandin transport","5/267","17/18866",2.94440618117367e-06,1.53619854363638e-05,5.50244305319701e-06,"NOS2/P2RX7/OXT/IL1B/LEP",5]
["GO:0031649","heat generation","5/267","17/18866",2.94440618117367e-06,1.53619854363638e-05,5.50244305319701e-06,"PTGS2/IL1A/CNR1/IL1B/TNF",5]
["GO:0051580","regulation of neurotransmitter uptake","5/267","17/18866",2.94440618117367e-06,1.53619854363638e-05,5.50244305319701e-06,"PER2/TOR1A/DRD2/GDNF/PRKN",5]
["GO:0090494","dopamine uptake","5/267","17/18866",2.94440618117367e-06,1.53619854363638e-05,5.50244305319701e-06,"TOR1A/SLC6A3/DRD2/GDNF/PRKN",5]
["GO:0001974","blood vessel remodeling","7/267","45/18866",3.01301671680534e-06,1.56220067154819e-05,5.5955789493931e-06,"BAX/TGFB1/FGF8/LIF/ACE/NOS3/CHD7",7]
["GO:0006775","fat-soluble vitamin metabolic process","7/267","45/18866",3.01301671680534e-06,1.56220067154819e-05,5.5955789493931e-06,"FGFR1/VDR/IFNG/IL1B/CYP27A1/CYP3A4/TNF",7]
["GO:0010677","negative regulation of cellular carbohydrate metabolic process","7/267","45/18866",3.01301671680534e-06,1.56220067154819e-05,5.5955789493931e-06,"HDAC4/GSK3B/EP300/PPARGC1A/ADIPOQ/PRKN/INS",7]
["GO:0031018","endocrine pancreas development","7/267","45/18866",3.01301671680534e-06,1.56220067154819e-05,5.5955789493931e-06,"PAX6/GSK3B/MEN1/IL6/AKT1/IL6R/DLL1",7]
["GO:0045429","positive regulation of nitric oxide biosynthetic process","7/267","45/18866",3.01301671680534e-06,1.56220067154819e-05,5.5955789493931e-06,"PTGS2/IFNG/PTK2B/IL1B/AKT1/MTOR/TNF",7]
["GO:0090311","regulation of protein deacetylation","7/267","45/18866",3.01301671680534e-06,1.56220067154819e-05,5.5955789493931e-06,"EP300/MAPK8/IFNG/VEGFA/TP53/MAPT/LRRK2",7]
["GO:0006970","response to osmotic stress","9/267","85/18866",3.2069170394367e-06,1.66101003920202e-05,5.94949994540616e-06,"PTGS2/ABCB1/BAX/TSPO/OXT/PTK2B/TP53/SST/TNF",9]
["GO:0042130","negative regulation of T cell proliferation","8/267","64/18866",3.23255372862563e-06,1.67082202557223e-05,5.98464507457225e-06,"DLG1/PRKAR1A/IDO1/IL10/GNRH1/SHH/PAWR/HLA-DRB1",8]
["GO:0045453","bone resorption","8/267","64/18866",3.23255372862563e-06,1.67082202557223e-05,5.98464507457225e-06,"CD38/P2RX7/PTK2B/RAC1/IL6/CTNNB1/CSF1R/NF1",8]
["GO:0035066","positive regulation of histone acetylation","6/267","30/18866",3.39087576669103e-06,1.74491740764478e-05,6.25004411563236e-06,"BRCA1/SMARCB1/MAPK3/PPARGC1A/IL1B/LIF",6]
["GO:0036475","neuron death in response to oxidative stress","6/267","30/18866",3.39087576669103e-06,1.74491740764478e-05,6.25004411563236e-06,"REST/HIF1A/ATF4/IL10/CTNNB1/PRKN",6]
["GO:0043457","regulation of cellular respiration","6/267","30/18866",3.39087576669103e-06,1.74491740764478e-05,6.25004411563236e-06,"NOS2/HIF1A/PPARGC1A/IFNG/PIK3CA/VCP",6]
["GO:1904837","beta-catenin-TCF complex assembly","6/267","30/18866",3.39087576669103e-06,1.74491740764478e-05,6.25004411563236e-06,"CREBBP/EP300/MEN1/KMT2D/CTNNB1/TLE1",6]
["GO:0006939","smooth muscle contraction","10/267","109/18866",3.39338033811952e-06,1.74491740764478e-05,6.25004411563236e-06,"CD38/PTGS2/DLG1/OXT/HTR2A/SRF/SOD1/DRD2/EDNRA/GDNF",10]
["GO:0007249","I-kappaB kinase/NF-kappaB signaling","16/267","286/18866",3.41884790580434e-06,1.75620448494661e-05,6.29047280914184e-06,"TNFRSF1A/ESR1/SIRT1/IL1B/AKT1/PLK2/S100B/SQSTM1/CTNNB1/FADD/PRKCE/ADIPOQ/PRKN/HLA-DRB1/TLE1/TNF",16]
["GO:1902652","secondary alcohol metabolic process","12/267","162/18866",3.45739727000759e-06,1.77418135345816e-05,6.35486337614853e-06,"PON1/FGFR1/APOB/CYP2D6/GNB3/APOE/CYP27A1/CYP1A2/SOD1/LBR/CYP3A4/LEP",12]
["GO:0022408","negative regulation of cell-cell adhesion","13/267","191/18866",3.46934623669269e-06,1.77848519094523e-05,6.37027910530733e-06,"DLG1/TGFB1/PRKAR1A/IL2/VEGFA/IDO1/IL10/AKT1/GNRH1/SHH/PAWR/ADIPOQ/HLA-DRB1",13]
["GO:0010863","positive regulation of phospholipase C activity","7/267","46/18866",3.5111972456548e-06,1.79257748952499e-05,6.42075569945916e-06,"FGFR1/ESR1/HTR2A/PDGFRB/NTRK2/EDNRA/BDNF",7]
["GO:0032309","icosanoid secretion","7/267","46/18866",3.5111972456548e-06,1.79257748952499e-05,6.42075569945916e-06,"NOS2/P2RX7/OXT/IL1B/DRD2/ACE/LEP",7]
["GO:1904407","positive regulation of nitric oxide metabolic process","7/267","46/18866",3.5111972456548e-06,1.79257748952499e-05,6.42075569945916e-06,"PTGS2/IFNG/PTK2B/IL1B/AKT1/MTOR/TNF",7]
["GO:2000142","regulation of DNA-templated transcription, initiation","7/267","46/18866",3.5111972456548e-06,1.79257748952499e-05,6.42075569945916e-06,"ESR1/SRF/CREB1/TP53/CTNNB1/JUN/MED12",7]
["GO:0048565","digestive tract development","11/267","135/18866",3.53223525221551e-06,1.80070806924603e-05,6.44987827094566e-06,"FGFR2/GLI2/HIF1A/SFRP1/NPY/SHH/RET/CTNNB1/CXCL8/BCL2/TNF",11]
["GO:0006112","energy reserve metabolic process","9/267","86/18866",3.53794235115233e-06,1.80070806924603e-05,6.44987827094566e-06,"IGF1/GSK3B/GNAS/POMC/PER2/AKT1/LEP/MTOR/INS",9]
["GO:0008589","regulation of smoothened signaling pathway","9/267","86/18866",3.53794235115233e-06,1.80070806924603e-05,6.44987827094566e-06,"CREBBP/FGFR2/PRKACA/GLI2/SFRP1/SHH/VCP/OTX2/PTCH1",9]
["GO:0060675","ureteric bud morphogenesis","8/267","65/18866",3.64153685253033e-06,1.85154720006965e-05,6.63197675254478e-06,"DLG1/FGF8/VEGFA/SHH/CTNNB1/GDNF/BCL2/PTCH1",8]
["GO:0009135","purine nucleoside diphosphate metabolic process","11/267","136/18866",3.79553978026526e-06,1.92592785801468e-05,6.89839761090145e-06,"IGF1/HDAC4/DLG1/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/INS",11]
["GO:0009179","purine ribonucleoside diphosphate metabolic process","11/267","136/18866",3.79553978026526e-06,1.92592785801468e-05,6.89839761090145e-06,"IGF1/HDAC4/DLG1/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/INS",11]
["GO:0070838","divalent metal ion transport","21/267","471/18866",3.88191168562493e-06,1.9677548270381e-05,7.04821582033316e-06,"PRKACA/PTGS2/BAX/P2RX7/TSPO/HTR2A/CCL2/VDR/OPRM1/PDGFRB/PTK2B/DRD2/NOS3/CDK5/CTNNB1/PRKCE/CHD7/BCL2/ATP2A2/F2/DMD",21]
["GO:0001942","hair follicle development","9/267","87/18866",3.89790492100931e-06,1.96787050258842e-05,7.04863015357865e-06,"NGFR/FGFR2/GLI2/SHH/CTNNB1/BCL2/HDAC2/NF1/TNF",9]
["GO:0051781","positive regulation of cell division","9/267","87/18866",3.89790492100931e-06,1.96787050258842e-05,7.04863015357865e-06,"FGFR2/TGFB1/FGF8/VEGFA/IL1A/IL1B/DRD2/SHH/PRKCE",9]
["GO:1904705","regulation of vascular associated smooth muscle cell proliferation","9/267","87/18866",3.89790492100931e-06,1.96787050258842e-05,7.04863015357865e-06,"IGF1/SOD2/MFN2/DNMT1/IL10/PTEN/JUN/ADIPOQ/TNF",9]
["GO:1990874","vascular associated smooth muscle cell proliferation","9/267","87/18866",3.89790492100931e-06,1.96787050258842e-05,7.04863015357865e-06,"IGF1/SOD2/MFN2/DNMT1/IL10/PTEN/JUN/ADIPOQ/TNF",9]
["GO:0018393","internal peptidyl-lysine acetylation","12/267","164/18866",3.92743740007764e-06,1.98077726652401e-05,7.09486033251666e-06,"CREBBP/BRCA1/SIRT1/SMARCB1/EP300/MAPK3/PPARGC1A/KMT2A/IL1B/LIF/BRCA2/MECP2",12]
["GO:0048872","homeostasis of number of cells","15/267","256/18866",3.95808234858323e-06,1.99220818210444e-05,7.13580423412872e-06,"BAX/P2RX7/HIF1A/GATA1/IL2/SRF/VEGFA/KRAS/IL6/SOD1/AKT1/NOS3/FADD/BCL2/PTPN11",15]
["GO:0090257","regulation of muscle system process","15/267","256/18866",3.95808234858323e-06,1.99220818210444e-05,7.13580423412872e-06,"IGF1/TNFRSF1B/TNFRSF1A/HDAC4/PRKACA/PTGS2/DLG1/OXT/PPARGC1A/SRF/SOD1/NOS3/ATP2A2/MTOR/DMD",15]
["GO:0032652","regulation of interleukin-1 production","10/267","111/18866",4.00193310844233e-06,2.00618996088881e-05,7.18588496221044e-06,"IGF1/P2RX7/IFNG/IL17A/IL6/IL10/LPL/HDAC2/AGER/TNF",10]
["GO:0042303","molting cycle","10/267","111/18866",4.00193310844233e-06,2.00618996088881e-05,7.18588496221044e-06,"NGFR/FGFR2/PTGS2/GLI2/SHH/CTNNB1/BCL2/HDAC2/NF1/TNF",10]
["GO:0042633","hair cycle","10/267","111/18866",4.00193310844233e-06,2.00618996088881e-05,7.18588496221044e-06,"NGFR/FGFR2/PTGS2/GLI2/SHH/CTNNB1/BCL2/HDAC2/NF1/TNF",10]
["GO:1903008","organelle disassembly","10/267","111/18866",4.00193310844233e-06,2.00618996088881e-05,7.18588496221044e-06,"HDAC6/TSPO/HIF1A/TSC2/PPARGC1A/MFN2/TP53/SQSTM1/VCP/PRKN",10]
["GO:0070230","positive regulation of lymphocyte apoptotic process","5/267","18/18866",4.02984310658236e-06,2.01210066311657e-05,7.20705625061414e-06,"BAX/P2RX7/IDO1/IL10/TP53",5]
["GO:0090493","catecholamine uptake","5/267","18/18866",4.02984310658236e-06,2.01210066311657e-05,7.20705625061414e-06,"TOR1A/SLC6A3/DRD2/GDNF/PRKN",5]
["GO:0150078","positive regulation of neuroinflammatory response","5/267","18/18866",4.02984310658236e-06,2.01210066311657e-05,7.20705625061414e-06,"IL1B/IL6/IL18/LRRK2/TNF",5]
["GO:1901524","regulation of mitophagy","5/267","18/18866",4.02984310658236e-06,2.01210066311657e-05,7.20705625061414e-06,"HDAC6/TSC2/MFN2/TP53/PRKN",5]
["GO:0042552","myelination","11/267","137/18866",4.07585704895481e-06,2.02713317597482e-05,7.26090055758318e-06,"TNFRSF1B/TG/DLG1/SOD1/AKT1/NTRK2/S100B/CTNNB1/PTEN/NF1/MTOR",11]
["GO:0045776","negative regulation of blood pressure","7/267","47/18866",4.0761900834743e-06,2.02713317597482e-05,7.26090055758318e-06,"NOS2/OXT/SOD2/CNR1/DRD2/NOS3/ADIPOQ",7]
["GO:0051150","regulation of smooth muscle cell differentiation","7/267","47/18866",4.0761900834743e-06,2.02713317597482e-05,7.26090055758318e-06,"FGFR2/SIRT1/SOD2/SRF/DNMT1/SHH/MECP2",7]
["GO:0060986","endocrine hormone secretion","7/267","47/18866",4.0761900834743e-06,2.02713317597482e-05,7.26090055758318e-06,"TAC1/FGFR1/GNAS/POMC/IL1B/LEP/PTPN11",7]
["GO:0032922","circadian regulation of gene expression","8/267","66/18866",4.0935659361114e-06,2.03172710924495e-05,7.27735536826752e-06,"NGFR/SIRT1/PPARGC1A/KMT2A/ATF4/PER2/DRD2/HDAC2",8]
["GO:0072171","mesonephric tubule morphogenesis","8/267","66/18866",4.0935659361114e-06,2.03172710924495e-05,7.27735536826752e-06,"DLG1/FGF8/VEGFA/SHH/CTNNB1/GDNF/BCL2/PTCH1",8]
["GO:0040013","negative regulation of locomotion","19/267","397/18866",4.13683964170186e-06,2.05116587199776e-05,7.34698223096375e-06,"SFRP1/TGFB1/CCL2/PPARGC1A/SRF/DUSP1/APOE/AKT1/GNRH1/DRD2/SHH/MECP2/BCL2/PTEN/ERBB4/ADIPOQ/NF1/DPP4/TNF",19]
["GO:0002675","positive regulation of acute inflammatory response","6/267","31/18866",4.15506315180013e-06,2.05611796996413e-05,7.36471993626668e-06,"TAC1/PTGS2/CNR1/IL1B/IL6/TNF",6]
["GO:0014044","Schwann cell development","6/267","31/18866",4.15506315180013e-06,2.05611796996413e-05,7.36471993626668e-06,"SOD1/AKT1/NTRK2/CDK5/MED12/NF1",6]
["GO:0045732","positive regulation of protein catabolic process","14/267","225/18866",4.17524706522138e-06,2.06406025709409e-05,7.39316807067339e-06,"GCLC/TNFRSF1B/GSK3B/IFNG/PTK2B/IL1B/APOE/AKT1/PLK2/VCP/PTEN/PRKN/LRRK2/TNF",14]
["GO:0009798","axis specification","9/267","88/18866",4.28887315700678e-06,2.11813488357417e-05,7.58685563408248e-06,"PAX6/SFRP1/SRF/KDM6A/SHH/OTX2/CTNNB1/PTCH1/DLL1",9]
["GO:0035967","cellular response to topologically incorrect protein","12/267","166/18866",4.45286278946911e-06,2.19695097903352e-05,7.86916359403788e-06,"BAX/HDAC6/XBP1/EP300/CCL2/ATF4/TOR1A/PIK3R1/ATF3/VCP/CXCL8/PRKN",12]
["GO:0071897","DNA biosynthetic process","13/267","196/18866",4.60963226473226e-06,2.27045179468338e-05,8.13243298337053e-06,"SIRT1/MAPK1/MAPK3/PDGFRB/DUSP1/PTK2B/MEN1/REV1/POLG/TP53/VCP/CTNNB1/ADIPOQ",13]
["GO:0051271","negative regulation of cellular component movement","19/267","400/18866",4.61093154377918e-06,2.27045179468338e-05,8.13243298337053e-06,"SFRP1/TGFB1/CCL2/PPARGC1A/SRF/DUSP1/APOE/AKT1/GNRH1/DRD2/SHH/MECP2/BCL2/PTEN/ERBB4/ADIPOQ/NF1/DPP4/TNF",19]
["GO:0007272","ensheathment of neurons","11/267","139/18866",4.69127531004718e-06,2.30093689814003e-05,8.24162625557869e-06,"TNFRSF1B/TG/DLG1/SOD1/AKT1/NTRK2/S100B/CTNNB1/PTEN/NF1/MTOR",11]
["GO:0008366","axon ensheathment","11/267","139/18866",4.69127531004718e-06,2.30093689814003e-05,8.24162625557869e-06,"TNFRSF1B/TG/DLG1/SOD1/AKT1/NTRK2/S100B/CTNNB1/PTEN/NF1/MTOR",11]
["GO:0009185","ribonucleoside diphosphate metabolic process","11/267","139/18866",4.69127531004718e-06,2.30093689814003e-05,8.24162625557869e-06,"IGF1/HDAC4/DLG1/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/INS",11]
["GO:0043401","steroid hormone mediated signaling pathway","11/267","139/18866",4.69127531004718e-06,2.30093689814003e-05,8.24162625557869e-06,"BRCA1/ESR1/HDAC6/SIRT1/EP300/SFRP1/NR3C1/ESR2/NR3C2/KMT2D/AR",11]
["GO:0001938","positive regulation of endothelial cell proliferation","10/267","113/18866",4.7029852108141e-06,2.30122959752214e-05,8.24267466282294e-06,"FGFR1/SIRT1/HIF1A/VEGFA/IL10/CDH13/AKT1/JUN/NF1/MTOR",10]
["GO:0014033","neural crest cell differentiation","9/267","89/18866",4.71302934529842e-06,2.30122959752214e-05,8.24267466282294e-06,"MAPK1/HIF1A/MAPK3/SFRP1/EDNRA/SHH/RET/GDNF/ERBB4",9]
["GO:0022404","molting cycle process","9/267","89/18866",4.71302934529842e-06,2.30122959752214e-05,8.24267466282294e-06,"NGFR/FGFR2/GLI2/SHH/CTNNB1/BCL2/HDAC2/NF1/TNF",9]
["GO:0022405","hair cycle process","9/267","89/18866",4.71302934529842e-06,2.30122959752214e-05,8.24267466282294e-06,"NGFR/FGFR2/GLI2/SHH/CTNNB1/BCL2/HDAC2/NF1/TNF",9]
["GO:1900274","regulation of phospholipase C activity","7/267","48/18866",4.71491663982606e-06,2.30122959752214e-05,8.24267466282294e-06,"FGFR1/ESR1/HTR2A/PDGFRB/NTRK2/EDNRA/BDNF",7]
["GO:0072511","divalent inorganic cation transport","21/267","478/18866",4.87660180871326e-06,2.3778196123931e-05,8.51700912109769e-06,"PRKACA/PTGS2/BAX/P2RX7/TSPO/HTR2A/CCL2/VDR/OPRM1/PDGFRB/PTK2B/DRD2/NOS3/CDK5/CTNNB1/PRKCE/CHD7/BCL2/ATP2A2/F2/DMD",21]
["GO:0002819","regulation of adaptive immune response","12/267","168/18866",5.03918183332546e-06,2.4545275829165e-05,8.79176607961702e-06,"TNFRSF1B/P2RX7/SIRT1/TGFB1/IL2/IL1B/IL6/IL10/IL18/FADD/AGER/TNF",12]
["GO:0034694","response to prostaglandin","6/267","32/18866",5.05358372769511e-06,2.4545275829165e-05,8.79176607961702e-06,"APOB/OXT/SFRP1/AKT1/GNRH1/PRKCE",6]
["GO:0048730","epidermis morphogenesis","6/267","32/18866",5.05358372769511e-06,2.4545275829165e-05,8.79176607961702e-06,"NGFR/FGFR2/GLI2/SHH/CTNNB1/BCL2",6]
["GO:0098810","neurotransmitter reuptake","6/267","32/18866",5.05358372769511e-06,2.4545275829165e-05,8.79176607961702e-06,"PER2/TOR1A/SLC6A3/DRD2/GDNF/PRKN",6]
["GO:0016101","diterpenoid metabolic process","10/267","114/18866",5.09176244466657e-06,2.46826892099225e-05,8.8409855835345e-06,"APOB/CYP2D6/TTR/APOE/CYP1A2/SRD5A1/CYP3A4/LPL/GPC6/ADH1C",10]
["GO:0022037","metencephalon development","10/267","114/18866",5.09176244466657e-06,2.46826892099225e-05,8.8409855835345e-06,"GLI2/PPARGC1A/TP53/RERE/CDK5/MAP2K1/MECP2/BCL2/PTPN11/DLL1",10]
["GO:1904377","positive regulation of protein localization to cell periphery","8/267","68/18866",5.1414613594104e-06,2.48994341101224e-05,8.91862050093244e-06,"DLG1/IFNG/AKT1/PIK3R1/SQSTM1/PRKCI/PRKCE/TNF",8]
["GO:0043112","receptor metabolic process","13/267","198/18866",5.1514249031457e-06,2.49235121525257e-05,8.92724491069415e-06,"HDAC6/HIF1A/TGFB1/IFNG/VEGFA/APOE/IL10/DRD2/CDK5/CXCL8/ADIPOQ/HDAC2/TNF",13]
["GO:0032095","regulation of response to food","5/267","19/18866",5.40600561159095e-06,2.60040327732887e-05,9.31427191369336e-06,"OPRM1/NPY/LEP/CCK/MTOR",5]
["GO:0034393","positive regulation of smooth muscle cell apoptotic process","5/267","19/18866",5.40600561159095e-06,2.60040327732887e-05,9.31427191369336e-06,"IFNG/SOD2/MFN2/ATF4/CDKN2A",5]
["GO:0060749","mammary gland alveolus development","5/267","19/18866",5.40600561159095e-06,2.60040327732887e-05,9.31427191369336e-06,"ESR1/HIF1A/VEGFA/AR/ERBB4",5]
["GO:0061377","mammary gland lobule development","5/267","19/18866",5.40600561159095e-06,2.60040327732887e-05,9.31427191369336e-06,"ESR1/HIF1A/VEGFA/AR/ERBB4",5]
["GO:1905288","vascular associated smooth muscle cell apoptotic process","5/267","19/18866",5.40600561159095e-06,2.60040327732887e-05,9.31427191369336e-06,"IGF1/SOD2/MFN2/ATF4/DNMT1",5]
["GO:1905459","regulation of vascular associated smooth muscle cell apoptotic process","5/267","19/18866",5.40600561159095e-06,2.60040327732887e-05,9.31427191369336e-06,"IGF1/SOD2/MFN2/ATF4/DNMT1",5]
["GO:0002673","regulation of acute inflammatory response","7/267","49/18866",5.43480412948038e-06,2.60922855947072e-05,9.3458828097036e-06,"TAC1/PTGS2/CNR1/IL1B/IL6/TNF/INS",7]
["GO:0090199","regulation of release of cytochrome c from mitochondria","7/267","49/18866",5.43480412948038e-06,2.60922855947072e-05,9.3458828097036e-06,"IGF1/BAX/TP53/AKT1/BCL2L1/PRKN/GPX1",7]
["GO:0006096","glycolytic process","10/267","115/18866",5.50807846082314e-06,2.63933164634261e-05,9.45370775324631e-06,"IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/INS",10]
["GO:0060419","heart growth","10/267","115/18866",5.50807846082314e-06,2.63933164634261e-05,9.45370775324631e-06,"IGF1/FGFR2/FGFR1/MAPK1/PRKAR1A/DUSP6/PDLIM5/PTEN/ERBB4/MTOR",10]
["GO:0006094","gluconeogenesis","9/267","91/18866",5.67022968739751e-06,2.71442539110027e-05,9.72268278638378e-06,"SIRT1/EP300/PPARGC1A/ATF4/PER2/ATF3/LEP/ADIPOQ/INS",9]
["GO:0071230","cellular response to amino acid stimulus","8/267","69/18866",5.74525130654157e-06,2.74413757720335e-05,9.82910757938691e-06,"GCLC/XBP1/COL1A1/DNMT1/NTRK2/BCL2L1/MTOR/TNF",8]
["GO:0009755","hormone-mediated signaling pathway","13/267","200/18866",5.74878410926237e-06,2.74413757720335e-05,9.82910757938691e-06,"BRCA1/ESR1/HDAC6/SIRT1/EP300/SFRP1/NR3C1/ESR2/NR3C2/SST/KMT2D/AR/PTPN11",13]
["GO:0017038","protein import","13/267","200/18866",5.74878410926237e-06,2.74413757720335e-05,9.82910757938691e-06,"PTGS2/MAPK1/TSC2/TGFB1/IFNG/APOE/TP53/AKT1/PIK3R1/SHH/LEP/LRRK2/NF1",13]
["GO:0007292","female gamete generation","11/267","142/18866",5.76650037634463e-06,2.74996527020905e-05,9.84998154065202e-06,"IGF1/PTGS2/SIRT1/PRKAR1A/PTK2B/BRCA2/NOS3/KMT2D/CTNNB1/BCL2/LEP",11]
["GO:0006757","ATP generation from ADP","10/267","116/18866",5.95355159097163e-06,2.83645831046959e-05,1.01597872168148e-05,"IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/INS",10]
["GO:0051170","import into nucleus","12/267","171/18866",6.04598231025973e-06,2.87774925406357e-05,1.03076854599682e-05,"PTGS2/MAPK1/TSC2/TGFB1/IFNG/TP53/AKT1/PIK3R1/SHH/LEP/LRRK2/NF1",12]
["GO:0010952","positive regulation of peptidase activity","13/267","201/18866",6.06980293545949e-06,2.8835895391769e-05,1.03286045243584e-05,"GRN/NGFR/REST/BAX/SIRT1/MAPK3/NGF/VCP/FADD/MAPT/CCK/AGER/TNF",13]
["GO:0031099","regeneration","13/267","201/18866",6.06980293545949e-06,2.8835895391769e-05,1.03286045243584e-05,"IGF1/GRN/TSPO/MTR/IL6/IL10/MAP2K1/BCL2/PTEN/JUN/ERBB4/PTCH1/GPX1",13]
["GO:0001975","response to amphetamine","6/267","33/18866",6.10373952354717e-06,2.88871767213943e-05,1.03469727617926e-05,"HDAC9/OXT/PPP1R1B/SOD1/DRD2/HDAC2",6]
["GO:0033028","myeloid cell apoptotic process","6/267","33/18866",6.10373952354717e-06,2.88871767213943e-05,1.03469727617926e-05,"SIRT1/IL6/CDKN2A/BCL2/PTEN/ADIPOQ",6]
["GO:0040018","positive regulation of multicellular organism growth","6/267","33/18866",6.10373952354717e-06,2.88871767213943e-05,1.03469727617926e-05,"POU1F1/CREB1/SLC6A3/DRD2/CHD7/BCL2",6]
["GO:2000758","positive regulation of peptidyl-lysine acetylation","6/267","33/18866",6.10373952354717e-06,2.88871767213943e-05,1.03469727617926e-05,"BRCA1/SMARCB1/MAPK3/PPARGC1A/IL1B/LIF",6]
["GO:0106027","neuron projection organization","9/267","92/18866",6.2082463941974e-06,2.93261818791179e-05,1.05042181185494e-05,"GSK3B/HDAC6/APOE/ADAM10/PDLIM5/CDK5/PTEN/LRRK2/INS",9]
["GO:1903321","negative regulation of protein modification by small protein conjugation or removal","9/267","92/18866",6.2082463941974e-06,2.93261818791179e-05,1.05042181185494e-05,"GCLC/TSPO/PER2/AKT1/SQSTM1/CDK5/CTNNB1/PRKCE/MTOR",9]
["GO:0010718","positive regulation of epithelial to mesenchymal transition","7/267","50/18866",6.24380620099939e-06,2.93276804906773e-05,1.05047548997356e-05,"TGFB1/COL1A1/IL1B/IL6/CTNNB1/HDAC2/MTOR",7]
["GO:0042987","amyloid precursor protein catabolic process","7/267","50/18866",6.24380620099939e-06,2.93276804906773e-05,1.05047548997356e-05,"IGF1/IFNG/APOE/ADAM10/NTRK2/AGER/TNF",7]
["GO:0046850","regulation of bone remodeling","7/267","50/18866",6.24380620099939e-06,2.93276804906773e-05,1.05047548997356e-05,"CD38/P2RX7/SFRP1/IL6/LEP/CSF1R/NF1",7]
["GO:0048546","digestive tract morphogenesis","7/267","50/18866",6.24380620099939e-06,2.93276804906773e-05,1.05047548997356e-05,"FGFR2/GLI2/HIF1A/SFRP1/SHH/CTNNB1/BCL2",7]
["GO:0071715","icosanoid transport","7/267","50/18866",6.24380620099939e-06,2.93276804906773e-05,1.05047548997356e-05,"NOS2/P2RX7/OXT/IL1B/DRD2/ACE/LEP",7]
["GO:1901571","fatty acid derivative transport","7/267","50/18866",6.24380620099939e-06,2.93276804906773e-05,1.05047548997356e-05,"NOS2/P2RX7/OXT/IL1B/DRD2/ACE/LEP",7]
["GO:0032374","regulation of cholesterol transport","8/267","70/18866",6.40795229070198e-06,3.00704001761983e-05,1.07707864482614e-05,"PON1/SIRT1/TSPO/APOE/SHH/LEP/ADIPOQ/PTCH1",8]
["GO:0007050","cell cycle arrest","14/267","234/18866",6.56307489164121e-06,3.07694205952719e-05,1.1021165545736e-05,"BRCA1/PRKACA/BAX/EP300/TGFB1/IFNG/DUSP1/TP53/PLK2/CDKN2A/CDK5/MAP2K1/CXCL8/MTOR",14]
["GO:0072331","signal transduction by p53 class mediator","15/267","267/18866",6.59306604815012e-06,3.08729186299699e-05,1.10582370586861e-05,"BRCA1/ATRX/BAX/SIRT1/EP300/TBP/BRCA2/TP53/AKT1/PLK2/CDK5/BCL2/EHMT1/PRKN/HDAC2",15]
["GO:0010212","response to ionizing radiation","11/267","144/18866",6.59751735993949e-06,3.08729186299699e-05,1.10582370586861e-05,"BRCA1/BAX/SIRT1/SFRP1/MEN1/BRCA2/POLG/TP53/BCL2L1/BCL2/GPX1",11]
["GO:0002532","production of molecular mediator involved in inflammatory response","9/267","93/18866",6.78940498457687e-06,3.17411040149741e-05,1.13692086229017e-05,"NOS2/GRN/IL17A/IDO1/IL6/LEP/F2/TNF/INS",9]
["GO:0006633","fatty acid biosynthetic process","12/267","173/18866",6.81160739224763e-06,3.18151129181407e-05,1.13957175515029e-05,"BRCA1/PTGS2/SIRT1/CYP2D6/XBP1/IL1B/CYP2E1/GSTM1/CYP1A2/CYP3A4/LPL/ADIPOQ",12]
["GO:0051209","release of sequestered calcium ion into cytosol","10/267","118/18866",6.93881854256724e-06,3.23789915729329e-05,1.15976908055305e-05,"PRKACA/BAX/P2RX7/HTR2A/PTK2B/DRD2/PRKCE/CHD7/F2/DMD",10]
["GO:0038127","ERBB signaling pathway","11/267","145/18866",7.05085693599985e-06,3.28710818687649e-05,1.17739504980724e-05,"ERBB3/MAPK1/TGFB1/PTK2B/PIK3CA/CDH13/AKT1/PIK3R1/BRAF/ERBB4/PTPN11",11]
["GO:0010042","response to manganese ion","5/267","20/18866",7.12491268064213e-06,3.31235465683856e-05,1.18643797357747e-05,"PTGS2/TSPO/ATF4/PRKN/LRRK2",5]
["GO:0010875","positive regulation of cholesterol efflux","5/267","20/18866",7.12491268064213e-06,3.31235465683856e-05,1.18643797357747e-05,"PON1/SIRT1/APOE/ADIPOQ/PTCH1",5]
["GO:1900409","positive regulation of cellular response to oxidative stress","5/267","20/18866",7.12491268064213e-06,3.31235465683856e-05,1.18643797357747e-05,"REST/HDAC6/SOD1/PAWR/TNF",5]
["GO:0032371","regulation of sterol transport","8/267","71/18866",7.13414037701951e-06,3.31355933976358e-05,1.18686947373867e-05,"PON1/SIRT1/TSPO/APOE/SHH/LEP/ADIPOQ/PTCH1",8]
["GO:0050435","amyloid-beta metabolic process","7/267","51/18866",7.15042354063704e-06,3.31803575635694e-05,1.18847286201744e-05,"IGF1/IFNG/APOE/ADAM10/NTRK2/ACE/TNF",7]
["GO:0060070","canonical Wnt signaling pathway","17/267","339/18866",7.28667613807244e-06,3.3781220016152e-05,1.209994894061e-05,"FGFR2/GSK3B/SFRP1/TGFB1/COL1A1/APOE/KDM6A/DVL3/SHH/VCP/CTNNB1/PTEN/FZD2/MED12/PRKN/LRRK2/TLE1",17]
["GO:0007616","long-term memory","6/267","34/18866",7.32427051310698e-06,3.38298637113258e-05,1.21173724151797e-05,"TAC1/SRF/APOE/DRD2/MECP2/MTOR",6]
["GO:0016242","negative regulation of macroautophagy","6/267","34/18866",7.32427051310698e-06,3.38298637113258e-05,1.21173724151797e-05,"TSC2/PIK3CA/TP53/AKT1/LRRK2/MTOR",6]
["GO:0030431","sleep","6/267","34/18866",7.32427051310698e-06,3.38298637113258e-05,1.21173724151797e-05,"OXT/HTR2A/SRD5A1/DRD2/IL18/FOS",6]
["GO:0042759","long-chain fatty acid biosynthetic process","6/267","34/18866",7.32427051310698e-06,3.38298637113258e-05,1.21173724151797e-05,"PTGS2/CYP2D6/CYP2E1/GSTM1/CYP1A2/CYP3A4",6]
["GO:0019319","hexose biosynthetic process","9/267","94/18866",7.41652219670655e-06,3.42243025214009e-05,1.22586547448238e-05,"SIRT1/EP300/PPARGC1A/ATF4/PER2/ATF3/LEP/ADIPOQ/INS",9]
["GO:0010822","positive regulation of mitochondrion organization","10/267","119/18866",7.48223234839003e-06,3.44320609359552e-05,1.23330708318357e-05,"GSK3B/BAX/HDAC6/HIF1A/MAPK8/PPARGC1A/MFN2/TP53/BCL2/PRKN",10]
["GO:0051153","regulation of striated muscle cell differentiation","10/267","119/18866",7.48223234839003e-06,3.44320609359552e-05,1.23330708318357e-05,"IGF1/HDAC9/HDAC4/XBP1/TGFB1/SHH/BCL2/BDNF/DLL1/MTOR",10]
["GO:0051283","negative regulation of sequestering of calcium ion","10/267","119/18866",7.48223234839003e-06,3.44320609359552e-05,1.23330708318357e-05,"PRKACA/BAX/P2RX7/HTR2A/PTK2B/DRD2/PRKCE/CHD7/F2/DMD",10]
["GO:0035966","response to topologically incorrect protein","13/267","205/18866",7.51795619180846e-06,3.45645996921728e-05,1.23805443150941e-05,"BAX/HDAC6/XBP1/EP300/CCL2/MFN2/ATF4/TOR1A/PIK3R1/ATF3/VCP/CXCL8/PRKN",13]
["GO:0014041","regulation of neuron maturation","4/267","10/18866",7.70339806055404e-06,3.52548730672286e-05,1.26277903467426e-05,"RET/BCL2/LRRK2/MTOR",4]
["GO:0033083","regulation of immature T cell proliferation","4/267","10/18866",7.70339806055404e-06,3.52548730672286e-05,1.26277903467426e-05,"IL1A/IL1B/GNRH1/SHH",4]
["GO:0034350","regulation of glial cell apoptotic process","4/267","10/18866",7.70339806055404e-06,3.52548730672286e-05,1.26277903467426e-05,"CCL2/PRKCI/CDK5/DLL1",4]
["GO:0045348","positive regulation of MHC class II biosynthetic process","4/267","10/18866",7.70339806055404e-06,3.52548730672286e-05,1.26277903467426e-05,"SIRT1/XBP1/IFNG/IL10",4]
["GO:0048755","branching morphogenesis of a nerve","4/267","10/18866",7.70339806055404e-06,3.52548730672286e-05,1.26277903467426e-05,"FGFR2/RERE/DRD2/LRRK2",4]
["GO:0045930","negative regulation of mitotic cell cycle","17/267","341/18866",7.87163673320547e-06,3.59918335246291e-05,1.28917590222827e-05,"BRCA1/DLG1/ATRX/BAX/EP300/TGFB1/CCL2/DUSP1/IL10/TP53/PLK2/CDKN2A/CTNNB1/BCL2L1/BCL2/PTEN/TNF",17]
["GO:0071383","cellular response to steroid hormone stimulus","13/267","206/18866",7.92448787086224e-06,3.61532127243364e-05,1.2949562739129e-05,"BRCA1/REST/ESR1/HDAC6/SIRT1/EP300/SFRP1/NR3C1/ESR2/SRD5A1/NR3C2/KMT2D/AR",13]
["GO:0045600","positive regulation of fat cell differentiation","8/267","72/18866",7.92865370181222e-06,3.61532127243364e-05,1.2949562739129e-05,"PTGS2/XBP1/HTR2A/SFRP1/CREB1/AKT1/LPL/INS",8]
["GO:0050663","cytokine secretion","8/267","72/18866",7.92865370181222e-06,3.61532127243364e-05,1.2949562739129e-05,"HDAC9/P2RX7/IFNG/IL1A/IL10/DRD2/TNF/INS",8]
["GO:0031103","axon regeneration","7/267","52/18866",8.16372441946987e-06,3.71572251836035e-05,1.33091856150068e-05,"GRN/TSPO/MTR/MAP2K1/BCL2/PTEN/JUN",7]
["GO:2001238","positive regulation of extrinsic apoptotic signaling pathway","7/267","52/18866",8.16372441946987e-06,3.71572251836035e-05,1.33091856150068e-05,"SFRP1/ATF3/RET/FADD/PTEN/NF1/TNF",7]
["GO:2000116","regulation of cysteine-type endopeptidase activity","14/267","239/18866",8.35741999383383e-06,3.80041876404484e-05,1.36125554304704e-05,"NGFR/PTGS2/REST/BAX/SIRT1/VEGFA/NGF/AKT1/VCP/FADD/MAPT/CCK/TNF/GPX1",14]
["GO:0002065","columnar/cuboidal epithelial cell differentiation","10/267","121/18866",8.68028256898703e-06,3.94005916972293e-05,1.41127273537885e-05,"PAX6/FGFR2/FGFR1/GSK3B/HIF1A/FGF8/NPY/MEN1/SOD1/DLL1",10]
["GO:0051282","regulation of sequestering of calcium ion","10/267","121/18866",8.68028256898703e-06,3.94005916972293e-05,1.41127273537885e-05,"PRKACA/BAX/P2RX7/HTR2A/PTK2B/DRD2/PRKCE/CHD7/F2/DMD",10]
["GO:0014046","dopamine secretion","6/267","35/18866",8.73540554782763e-06,3.95788383850303e-05,1.41765727631666e-05,"HTR2A/CNR1/DRD2/GDNF/SNCG/PRKN",6]
["GO:0014059","regulation of dopamine secretion","6/267","35/18866",8.73540554782763e-06,3.95788383850303e-05,1.41765727631666e-05,"HTR2A/CNR1/DRD2/GDNF/SNCG/PRKN",6]
["GO:0072078","nephron tubule morphogenesis","8/267","73/18866",8.79660167391657e-06,3.98199747578109e-05,1.42629443565246e-05,"DLG1/FGF8/VEGFA/SHH/CTNNB1/GDNF/BCL2/PTCH1",8]
["GO:0060401","cytosolic calcium ion transport","12/267","178/18866",9.10949721194258e-06,4.11990213579976e-05,1.47568990876148e-05,"PRKACA/BAX/P2RX7/HTR2A/PTK2B/DRD2/PRKCE/CHD7/BCL2/ATP2A2/F2/DMD",12]
["GO:0031061","negative regulation of histone methylation","5/267","21/18866",9.24367587782235e-06,4.17302655135326e-05,1.49471831316457e-05,"BRCA1/SIRT1/SMARCB1/DNMT1/PAX5",5]
["GO:0090201","negative regulation of release of cytochrome c from mitochondria","5/267","21/18866",9.24367587782235e-06,4.17302655135326e-05,1.49471831316457e-05,"IGF1/AKT1/BCL2L1/PRKN/GPX1",5]
["GO:0032731","positive regulation of interleukin-1 beta production","7/267","53/18866",9.29336515220924e-06,4.19166867253665e-05,1.50139565383954e-05,"P2RX7/IFNG/IL17A/IL6/LPL/AGER/TNF",7]
["GO:0007265","Ras protein signal transduction","17/267","346/18866",9.5223960494358e-06,4.29109417642897e-05,1.53700844461252e-05,"IGF1/NGFR/PDGFRB/MFN2/STMN1/APOE/DNMT1/KRAS/NGF/RAC1/CDH13/TP53/PLK2/CDKN2A/SQSTM1/JUN/NF1",17]
["GO:0048704","embryonic skeletal system morphogenesis","9/267","97/18866",9.60392572527658e-06,4.32003613930684e-05,1.54737504099051e-05,"COL11A1/FGFR2/DLG1/GNAS/FGF8/COL2A1/CTNNB1/MED12/PAX5",9]
["GO:0071674","mononuclear cell migration","9/267","97/18866",9.60392572527658e-06,4.32003613930684e-05,1.54737504099051e-05,"MAPK1/MAPK3/CCL2/DUSP1/IL6/IL6R/CSF1R/AGER/TNF",9]
["GO:0045216","cell-cell junction organization","13/267","210/18866",9.7512460162436e-06,4.38235565788518e-05,1.56969699953554e-05,"PRKACA/DLG1/TGFB1/SRF/VEGFA/IL1B/ADAM10/CDH13/ACE/PRKCI/CTNNB1/CSF1R/TNF",13]
["GO:0022898","regulation of transmembrane transporter activity","15/267","276/18866",9.81022968020928e-06,4.40489899220188e-05,1.57777169885229e-05,"PRKACA/DLG1/ABCB1/CCL2/PPARGC1A/IFNG/OPRM1/PTK2B/DRD2/CDK5/PRKCE/BCL2/PTEN/DMD/INS",15]
["GO:0002703","regulation of leukocyte mediated immunity","13/267","211/18866",1.02621893359565e-05,4.60369374253644e-05,1.64897712978579e-05,"NOS2/TNFRSF1B/P2RX7/TGFB1/IL2/IL1B/IL6/IL10/IL18/FADD/LEP/AGER/TNF",13]
["GO:0001569","branching involved in blood vessel morphogenesis","6/267","36/18866",1.03589114969128e-05,4.62216667596831e-05,1.65559386983254e-05,"FGF8/SRF/VEGFA/EDNRA/SHH/CTNNB1",6]
["GO:0010092","specification of animal organ identity","6/267","36/18866",1.03589114969128e-05,4.62216667596831e-05,1.65559386983254e-05,"FGFR2/FGFR1/FGF8/CTNNB1/GDNF/AR",6]
["GO:0034405","response to fluid shear stress","6/267","36/18866",1.03589114969128e-05,4.62216667596831e-05,1.65559386983254e-05,"PTGS2/P2RX7/PDGFRB/PTK2B/AKT1/NOS3",6]
["GO:0070873","regulation of glycogen metabolic process","6/267","36/18866",1.03589114969128e-05,4.62216667596831e-05,1.65559386983254e-05,"IGF1/GSK3B/POMC/AKT1/MTOR/INS",6]
["GO:1905332","positive regulation of morphogenesis of an epithelium","6/267","36/18866",1.03589114969128e-05,4.62216667596831e-05,1.65559386983254e-05,"VEGFA/LIF/CTNNB1/GDNF/AR/MTOR",6]
["GO:2000310","regulation of NMDA receptor activity","6/267","36/18866",1.03589114969128e-05,4.62216667596831e-05,1.65559386983254e-05,"DLG1/CCL2/PPARGC1A/IFNG/OPRM1/PTK2B",6]
["GO:2000179","positive regulation of neural precursor cell proliferation","7/267","54/18866",1.05496104367277e-05,4.70305400987332e-05,1.68456655375943e-05,"PAX6/GLI2/HIF1A/VEGFA/DRD2/SHH/CTNNB1",7]
["GO:0033143","regulation of intracellular steroid hormone receptor signaling pathway","8/267","75/18866",1.07746511606878e-05,4.79176319225643e-05,1.71634091172772e-05,"BRCA1/ESR1/HDAC6/SIRT1/EP300/SFRP1/KMT2D/AR",8]
["GO:1900076","regulation of cellular response to insulin stimulus","8/267","75/18866",1.07746511606878e-05,4.79176319225643e-05,1.71634091172772e-05,"SIRT1/TSC2/IL1B/PIK3R1/LEP/LPL/PTPN11/INS",8]
["GO:0046031","ADP metabolic process","10/267","124/18866",1.07869854358026e-05,4.79176319225643e-05,1.71634091172772e-05,"IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/INS",10]
["GO:0051208","sequestering of calcium ion","10/267","124/18866",1.07869854358026e-05,4.79176319225643e-05,1.71634091172772e-05,"PRKACA/BAX/P2RX7/HTR2A/PTK2B/DRD2/PRKCE/CHD7/F2/DMD",10]
["GO:0010717","regulation of epithelial to mesenchymal transition","9/267","99/18866",1.13501568138578e-05,5.02851224237728e-05,1.8011410289772e-05,"SFRP1/TGFB1/COL1A1/IL1B/IL6/CTNNB1/PTEN/HDAC2/MTOR",9]
["GO:0051817","modulation of process of other organism involved in symbiotic interaction","9/267","99/18866",1.13501568138578e-05,5.02851224237728e-05,1.8011410289772e-05,"REST/SMARCB1/EP300/APOE/CRP/BCL2L1/JUN/CSF1R/PRKN",9]
["GO:0090277","positive regulation of peptide hormone secretion","9/267","99/18866",1.13501568138578e-05,5.02851224237728e-05,1.8011410289772e-05,"CD38/ACSL4/HIF1A/GLUL/RAC1/DRD2/PRKCE/HLA-DRB1/INS",9]
["GO:0048593","camera-type eye morphogenesis","10/267","125/18866",1.15808419462401e-05,5.12616523382772e-05,1.83611893119278e-05,"PAX6/BAX/HIF1A/VEGFA/MFN2/ATF4/NTRK2/CTNNB1/NF1/DLL1",10]
["GO:0002822","regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","11/267","153/18866",1.17662685620363e-05,5.19902468409268e-05,1.86221614223565e-05,"TNFRSF1B/P2RX7/TGFB1/IL2/IL1B/IL6/IL10/IL18/FADD/AGER/TNF",11]
["GO:0008203","cholesterol metabolic process","11/267","153/18866",1.17662685620363e-05,5.19902468409268e-05,1.86221614223565e-05,"PON1/APOB/CYP2D6/GNB3/APOE/CYP27A1/CYP1A2/SOD1/LBR/CYP3A4/LEP",11]
["GO:0034104","negative regulation of tissue remodeling","5/267","22/18866",1.1824583612304e-05,5.21556059860724e-05,1.8681390698628e-05,"CD38/P2RX7/SFRP1/IL6/AGER",5]
["GO:1902884","positive regulation of response to oxidative stress","5/267","22/18866",1.1824583612304e-05,5.21556059860724e-05,1.8681390698628e-05,"REST/HDAC6/SOD1/PAWR/TNF",5]
["GO:0050433","regulation of catecholamine secretion","7/267","55/18866",1.19433535439561e-05,5.2521516008766e-05,1.88124544254363e-05,"OXT/HTR2A/CNR1/DRD2/GDNF/SNCG/PRKN",7]
["GO:0031652","positive regulation of heat generation","4/267","11/18866",1.19706559619419e-05,5.2521516008766e-05,1.88124544254363e-05,"PTGS2/CNR1/IL1B/TNF",4]
["GO:0033079","immature T cell proliferation","4/267","11/18866",1.19706559619419e-05,5.2521516008766e-05,1.88124544254363e-05,"IL1A/IL1B/GNRH1/SHH",4]
["GO:0048853","forebrain morphogenesis","4/267","11/18866",1.19706559619419e-05,5.2521516008766e-05,1.88124544254363e-05,"FGF8/HESX1/PTEN/NF1",4]
["GO:0070933","histone H4 deacetylation","4/267","11/18866",1.19706559619419e-05,5.2521516008766e-05,1.88124544254363e-05,"HDAC9/HDAC4/REST/HDAC2",4]
["GO:1900112","regulation of histone H3-K9 trimethylation","4/267","11/18866",1.19706559619419e-05,5.2521516008766e-05,1.88124544254363e-05,"ATRX/SIRT1/SMARCB1/MECP2",4]
["GO:1903034","regulation of response to wounding","12/267","183/18866",1.20603733281542e-05,5.28686953709164e-05,1.89368090980398e-05,"GRN/XBP1/APOE/IL10/NOS3/MAP2K1/PRKCE/PTEN/F2/MTOR/AGER/TNF",12]
["GO:0035137","hindlimb morphogenesis","6/267","37/18866",1.22181405083877e-05,5.35133118933157e-05,1.91677014993082e-05,"GNAS/FGF8/SHH/CTNNB1/CHD7/PTCH1",6]
["GO:0046364","monosaccharide biosynthetic process","9/267","100/18866",1.23203619715121e-05,5.39137312215247e-05,1.93111259648498e-05,"SIRT1/EP300/PPARGC1A/ATF4/PER2/ATF3/LEP/ADIPOQ/INS",9]
["GO:0055007","cardiac muscle cell differentiation","10/267","126/18866",1.24245597893639e-05,5.43220902174201e-05,1.9457394305585e-05,"IGF1/TGFB1/SRF/VEGFA/PDGFRB/KDM6B/PDLIM5/NEB/DLL1/MTOR",10]
["GO:0002695","negative regulation of leukocyte activation","12/267","184/18866",1.2741790194637e-05,5.56603310952076e-05,1.9936733011639e-05,"GRN/DLG1/SFRP1/PRKAR1A/IL2/CNR1/IDO1/IL10/GNRH1/SHH/PAWR/HLA-DRB1",12]
["GO:0006913","nucleocytoplasmic transport","17/267","354/18866",1.28143511051104e-05,5.59283698145245e-05,2.00327406400281e-05,"PRKACA/PTGS2/GSK3B/MAPK1/TSC2/TGFB1/IFNG/IL1B/TP53/AKT1/PIK3R1/SHH/CDK5/LEP/PTPN11/LRRK2/NF1",17]
["GO:0061333","renal tubule morphogenesis","8/267","77/18866",1.31149425515802e-05,5.71903128035283e-05,2.04847505356329e-05,"DLG1/FGF8/VEGFA/SHH/CTNNB1/GDNF/BCL2/PTCH1",8]
["GO:0009132","nucleoside diphosphate metabolic process","11/267","155/18866",1.33044146376764e-05,5.79659182250594e-05,2.07625612835603e-05,"IGF1/HDAC4/DLG1/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/INS",11]
["GO:0001704","formation of primary germ layer","10/267","127/18866",1.33207182185666e-05,5.79863522801248e-05,2.07698804692743e-05,"COL11A1/FGFR2/PRKACA/FGFR1/PRKAR1A/SRF/DUSP1/KDM6B/KDM6A/CTNNB1",10]
["GO:0001708","cell fate specification","9/267","101/18866",1.336043427259e-05,5.80075202809061e-05,2.07774625438265e-05,"PAX6/POU1F1/GLI2/FGFR1/SHH/CTNNB1/AR/PTCH1/DLL1",9]
["GO:0010522","regulation of calcium ion transport into cytosol","9/267","101/18866",1.336043427259e-05,5.80075202809061e-05,2.07774625438265e-05,"PRKACA/BAX/P2RX7/PTK2B/PRKCE/CHD7/BCL2/F2/DMD",9]
["GO:0032637","interleukin-8 production","9/267","101/18866",1.336043427259e-05,5.80075202809061e-05,2.07774625438265e-05,"NOS2/IL1B/CRP/IL6/IL10/FADD/LEP/ADIPOQ/TNF",9]
["GO:0072521","purine-containing compound metabolic process","20/267","472/18866",1.39680250971638e-05,6.0592831720364e-05,2.17034840551295e-05,"NOS2/IGF1/HDAC4/ACSL4/DLG1/P2RX7/ADA2/EP300/HIF1A/HTR2A/TGFB1/PPARGC1A/IFNG/TTR/LDHA/NOS3/VCP/LRRK2/GPX1/INS",20]
["GO:0051169","nuclear transport","17/267","357/18866",1.42897977084809e-05,6.18221157536542e-05,2.21437959807854e-05,"PRKACA/PTGS2/GSK3B/MAPK1/TSC2/TGFB1/IFNG/IL1B/TP53/AKT1/PIK3R1/SHH/CDK5/LEP/PTPN11/LRRK2/NF1",17]
["GO:0003156","regulation of animal organ formation","6/267","38/18866",1.43380753139859e-05,6.18221157536542e-05,2.21437959807854e-05,"FGFR1/FGF8/SHH/CTNNB1/GDNF/AR",6]
["GO:0032885","regulation of polysaccharide biosynthetic process","6/267","38/18866",1.43380753139859e-05,6.18221157536542e-05,2.21437959807854e-05,"IGF1/GSK3B/TGFB1/AKT1/MTOR/INS",6]
["GO:0043029","T cell homeostasis","6/267","38/18866",1.43380753139859e-05,6.18221157536542e-05,2.21437959807854e-05,"BAX/P2RX7/IL2/AKT1/FADD/BCL2",6]
["GO:0048009","insulin-like growth factor receptor signaling pathway","6/267","38/18866",1.43380753139859e-05,6.18221157536542e-05,2.21437959807854e-05,"IGF1/POU1F1/TSC2/AKT1/PIK3R1/AR",6]
["GO:0051930","regulation of sensory perception of pain","6/267","38/18866",1.43380753139859e-05,6.18221157536542e-05,2.21437959807854e-05,"COMT/OXT/OPRM1/IL10/CCK/MTOR",6]
["GO:0071392","cellular response to estradiol stimulus","6/267","38/18866",1.43380753139859e-05,6.18221157536542e-05,2.21437959807854e-05,"ESR1/SFRP1/PPARGC1A/IL10/ESR2/SRD5A1",6]
["GO:0042310","vasoconstriction","8/267","78/18866",1.44368500513134e-05,6.21942987974185e-05,2.22771066138518e-05,"CD38/PTGS2/HTR2A/PER2/AKT1/EDNRA/ACE/LEP",8]
["GO:2000060","positive regulation of ubiquitin-dependent protein catabolic process","9/267","102/18866",1.44744451001607e-05,6.23025037802608e-05,2.23158640881788e-05,"GCLC/GSK3B/PTK2B/AKT1/PLK2/VCP/PTEN/PRKN/LRRK2",9]
["GO:0006338","chromatin remodeling","13/267","218/18866",1.45482972338901e-05,6.25664496889003e-05,2.24104057304314e-05,"ARID1B/HDAC4/ATRX/ESR1/SIRT1/SMARCB1/DNMT1/KDM6B/RERE/KDM6A/CDKN2A/CHD7/HDAC2",13]
["GO:0007617","mating behavior","5/267","23/18866",1.49351681941545e-05,6.38999955384863e-05,2.28880627446611e-05,"HDAC4/OXT/PPP1R1B/PTEN/HDAC2",5]
["GO:0030539","male genitalia development","5/267","23/18866",1.49351681941545e-05,6.38999955384863e-05,2.28880627446611e-05,"FGF8/SRD5A1/SHH/CTNNB1/AR",5]
["GO:0031281","positive regulation of cyclase activity","5/267","23/18866",1.49351681941545e-05,6.38999955384863e-05,2.28880627446611e-05,"NOS2/MAPK3/MAPK8/NOS3/NF1",5]
["GO:0032098","regulation of appetite","5/267","23/18866",1.49351681941545e-05,6.38999955384863e-05,2.28880627446611e-05,"OPRM1/POMC/NPY/LEP/CCK",5]
["GO:0060445","branching involved in salivary gland morphogenesis","5/267","23/18866",1.49351681941545e-05,6.38999955384863e-05,2.28880627446611e-05,"FGFR2/FGFR1/FGF8/SHH/TNF",5]
["GO:0090343","positive regulation of cell aging","5/267","23/18866",1.49351681941545e-05,6.38999955384863e-05,2.28880627446611e-05,"SIRT1/KRAS/TP53/CDKN2A/PAWR",5]
["GO:0002285","lymphocyte activation involved in immune response","12/267","187/18866",1.4992223921303e-05,6.40891901019399e-05,2.29558295262201e-05,"XBP1/TGFB1/IL2/IFNG/PTK2B/IL6/IL10/TP53/IL18/IFNA1/DLL1/MTOR",12]
["GO:0001541","ovarian follicle development","7/267","57/18866",1.51901690308256e-05,6.47690127847243e-05,2.31993322696505e-05,"BAX/ESR1/VEGFA/SOD1/GNRH1/BCL2L1/BCL2",7]
["GO:0042743","hydrogen peroxide metabolic process","7/267","57/18866",1.51901690308256e-05,6.47690127847243e-05,2.31993322696505e-05,"HDAC6/TPO/RAC1/CYP1A2/SOD1/GPX1/HP",7]
["GO:0071398","cellular response to fatty acid","7/267","57/18866",1.51901690308256e-05,6.47690127847243e-05,2.31993322696505e-05,"APOB/SFRP1/PPARGC1A/CREB1/AKT1/PRKCE/LPL",7]
["GO:0009952","anterior/posterior pattern specification","13/267","219/18866",1.5274027852766e-05,6.50710077379357e-05,2.33075025344435e-05,"PAX6/GLI2/EP300/SFRP1/FGF8/SRF/TP53/KDM6A/SHH/OTX2/CTNNB1/MED12/DLL1",13]
["GO:0060047","heart contraction","15/267","287/18866",1.558732902207e-05,6.63491336804736e-05,2.37653089321102e-05,"TAC1/HDAC4/PRKACA/DLG1/OXT/IL2/PIK3CA/SOD1/DRD2/ACE/NOS3/ATP2A2/MTOR/DMD/GPX1",15]
["GO:0043123","positive regulation of I-kappaB kinase/NF-kappaB signaling","12/267","188/18866",1.58158575213137e-05,6.72645456592157e-05,2.40931963854676e-05,"TNFRSF1A/IL1B/AKT1/PLK2/S100B/CTNNB1/FADD/PRKCE/ADIPOQ/PRKN/HLA-DRB1/TNF",12]
["GO:0090398","cellular senescence","8/267","79/18866",1.58690668070488e-05,6.74334047383782e-05,2.41536792879515e-05,"SIRT1/SRF/KRAS/TP53/PLK2/CDKN2A/MAP2K1/PAWR",8]
["GO:0001818","negative regulation of cytokine production","17/267","360/18866",1.59151370966839e-05,6.75716662616861e-05,2.4203202584377e-05,"IGF1/HDAC9/FGFR1/TSPO/TGFB1/IFNG/POMC/IDO1/RAC1/IL10/F2/ADIPOQ/HLA-DRB1/DLL1/AGER/TNF/MC1R",17]
["GO:0060402","calcium ion transport into cytosol","11/267","158/18866",1.59384596789728e-05,6.76131938633058e-05,2.4218077176206e-05,"PRKACA/BAX/P2RX7/HTR2A/PTK2B/DRD2/PRKCE/CHD7/BCL2/F2/DMD",11]
["GO:0009410","response to xenobiotic stimulus","10/267","130/18866",1.63511951317894e-05,6.9305192948238e-05,2.48241270028685e-05,"GCLC/CYP2D6/CYP2E1/GSTM1/CYP1A2/CYP3A4/CYP2C19/NQO1/CYP2B6/GPX1",10]
["GO:0045926","negative regulation of growth","14/267","254/18866",1.66175006370622e-05,7.03741990507647e-05,2.52070296704332e-05,"FGFR3/SIRT1/HIF1A/SFRP1/TGFB1/ESR2/TP53/CDKN2A/CDK5/BCL2/PTEN/PTCH1/DCC/MEG3",14]
["GO:0034205","amyloid-beta formation","6/267","39/18866",1.67453725089285e-05,7.07956350017613e-05,2.53579819890989e-05,"IGF1/IFNG/APOE/ADAM10/NTRK2/TNF",6]
["GO:0051931","regulation of sensory perception","6/267","39/18866",1.67453725089285e-05,7.07956350017613e-05,2.53579819890989e-05,"COMT/OXT/OPRM1/IL10/CCK/MTOR",6]
["GO:0002367","cytokine production involved in immune response","9/267","104/18866",1.69414656529393e-05,7.15035824219154e-05,2.56115586104408e-05,"TNFRSF1B/DLG1/SIRT1/TGFB1/IL1B/IL6/IL10/IL18/TNF",9]
["GO:0003300","cardiac muscle hypertrophy","9/267","104/18866",1.69414656529393e-05,7.15035824219154e-05,2.56115586104408e-05,"IGF1/TNFRSF1B/TNFRSF1A/HDAC4/PDLIM5/ATP2A2/LEP/HDAC2/MTOR",9]
["GO:1903793","positive regulation of anion transport","7/267","58/18866",1.70683498432703e-05,7.19782692292641e-05,2.57815846227918e-05,"ABCB1/P2RX7/OXT/IL1B/ATF4/APOE/CCK",7]
["GO:0006936","muscle contraction","17/267","362/18866",1.70884097626581e-05,7.20020505864572e-05,2.57901027641626e-05,"CD38/HDAC4/PRKACA/PTGS2/DLG1/OXT/HTR2A/SRF/PIK3CA/SOD1/DRD2/EDNRA/GDNF/ATP2A2/NEB/MTOR/DMD",17]
["GO:0014032","neural crest cell development","8/267","80/18866",1.74188625079551e-05,7.32707502124851e-05,2.62445327903301e-05,"MAPK1/HIF1A/MAPK3/EDNRA/SHH/RET/GDNF/ERBB4",8]
["GO:0031397","negative regulation of protein ubiquitination","8/267","80/18866",1.74188625079551e-05,7.32707502124851e-05,2.62445327903301e-05,"GCLC/TSPO/PER2/AKT1/SQSTM1/CDK5/PRKCE/MTOR",8]
["GO:0003206","cardiac chamber morphogenesis","10/267","131/18866",1.74850154809432e-05,7.34253005015553e-05,2.62998904892412e-05,"COL11A1/FGFR2/HIF1A/TGFB1/FGF8/SRF/TP53/NOS3/CHD7/FZD2",10]
["GO:0006766","vitamin metabolic process","10/267","131/18866",1.74850154809432e-05,7.34253005015553e-05,2.62998904892412e-05,"GCLC/FGFR1/VDR/IFNG/MTR/IL1B/CYP27A1/CYP3A4/MTHFR/TNF",10]
["GO:0060442","branching involved in prostate gland morphogenesis","4/267","12/18866",1.77562927156452e-05,7.4314475716024e-05,2.66183803095966e-05,"FGFR2/ESR1/SFRP1/SHH",4]
["GO:0071679","commissural neuron axon guidance","4/267","12/18866",1.77562927156452e-05,7.4314475716024e-05,2.66183803095966e-05,"VEGFA/NCAM1/GDNF/PTCH1",4]
["GO:0072537","fibroblast activation","4/267","12/18866",1.77562927156452e-05,7.4314475716024e-05,2.66183803095966e-05,"GCLC/IL17A/PDGFRB/LEP",4]
["GO:1902337","regulation of apoptotic process involved in morphogenesis","4/267","12/18866",1.77562927156452e-05,7.4314475716024e-05,2.66183803095966e-05,"TNFRSF1B/TNFRSF1A/BAX/VDR",4]
["GO:0021549","cerebellum development","9/267","105/18866",1.83035308255301e-05,7.64765936501018e-05,2.73928199714385e-05,"GLI2/PPARGC1A/TP53/RERE/CDK5/MAP2K1/MECP2/PTPN11/DLL1",9]
["GO:0030301","cholesterol transport","9/267","105/18866",1.83035308255301e-05,7.64765936501018e-05,2.73928199714385e-05,"PON1/APOB/SIRT1/TSPO/APOE/SHH/LEP/ADIPOQ/PTCH1",9]
["GO:0001759","organ induction","5/267","24/18866",1.86482565632916e-05,7.75276811161655e-05,2.77693044401879e-05,"FGFR1/FGF8/CTNNB1/GDNF/AR",5]
["GO:0010869","regulation of receptor biosynthetic process","5/267","24/18866",1.86482565632916e-05,7.75276811161655e-05,2.77693044401879e-05,"HDAC6/HIF1A/IFNG/ADIPOQ/HDAC2",5]
["GO:0034695","response to prostaglandin E","5/267","24/18866",1.86482565632916e-05,7.75276811161655e-05,2.77693044401879e-05,"OXT/SFRP1/AKT1/GNRH1/PRKCE",5]
["GO:0036003","positive regulation of transcription from RNA polymerase II promoter in response to stress","5/267","24/18866",1.86482565632916e-05,7.75276811161655e-05,2.77693044401879e-05,"HIF1A/VEGFA/ATF4/TP53/ATF3",5]
["GO:0050995","negative regulation of lipid catabolic process","5/267","24/18866",1.86482565632916e-05,7.75276811161655e-05,2.77693044401879e-05,"CNR1/IL1B/AKT1/TNF/INS",5]
["GO:2000637","positive regulation of gene silencing by miRNA","5/267","24/18866",1.86482565632916e-05,7.75276811161655e-05,2.77693044401879e-05,"TGFB1/MAP2K2/IL6/TP53/MAP2K1",5]
["GO:0031102","neuron projection regeneration","7/267","59/18866",1.91342842115578e-05,7.94820973945991e-05,2.84693483452463e-05,"GRN/TSPO/MTR/MAP2K1/BCL2/PTEN/JUN",7]
["GO:0048713","regulation of oligodendrocyte differentiation","6/267","40/18866",1.94684037455614e-05,8.06686638187452e-05,2.88943594354302e-05,"TNFRSF1B/SHH/CTNNB1/HDAC2/NF1/MTOR",6]
["GO:0072210","metanephric nephron development","6/267","40/18866",1.94684037455614e-05,8.06686638187452e-05,2.88943594354302e-05,"PDGFRB/LIF/RET/CTNNB1/GDNF/ADIPOQ",6]
["GO:1902991","regulation of amyloid precursor protein catabolic process","6/267","40/18866",1.94684037455614e-05,8.06686638187452e-05,2.88943594354302e-05,"IGF1/IFNG/APOE/NTRK2/AGER/TNF",6]
["GO:0032611","interleukin-1 beta production","9/267","106/18866",1.97576554151381e-05,8.1799314666488e-05,2.92993423673908e-05,"IGF1/P2RX7/IFNG/IL17A/IL1B/IL6/LPL/AGER/TNF",9]
["GO:0006165","nucleoside diphosphate phosphorylation","10/267","133/18866",1.99567225481284e-05,8.25550254207167e-05,2.95700271305718e-05,"IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/INS",10]
["GO:1903050","regulation of proteolysis involved in cellular protein catabolic process","13/267","225/18866",2.03344053397159e-05,8.40477531963587e-05,3.01047008297118e-05,"GCLC/PRKACA/GSK3B/PTK2B/APOE/AKT1/PLK2/SHH/VCP/PTEN/PRKN/LRRK2/GPX1",13]
["GO:0007498","mesoderm development","10/267","134/18866",2.13012117434238e-05,8.77847403971975e-05,3.14432360957633e-05,"FGFR2/PRKACA/FGFR1/FGF8/PRKAR1A/SRF/VEGFA/KDM6B/KDM6A/SHH",10]
["GO:0043280","positive regulation of cysteine-type endopeptidase activity involved in apoptotic process","10/267","134/18866",2.13012117434238e-05,8.77847403971975e-05,3.14432360957633e-05,"NGFR/REST/BAX/SIRT1/NGF/VCP/FADD/MAPT/CCK/TNF",10]
["GO:0014897","striated muscle hypertrophy","9/267","107/18866",2.13088534671347e-05,8.77847403971975e-05,3.14432360957633e-05,"IGF1/TNFRSF1B/TNFRSF1A/HDAC4/PDLIM5/ATP2A2/LEP/HDAC2/MTOR",9]
["GO:0055017","cardiac muscle tissue growth","9/267","107/18866",2.13088534671347e-05,8.77847403971975e-05,3.14432360957633e-05,"IGF1/FGFR2/FGFR1/MAPK1/PRKAR1A/PDLIM5/PTEN/ERBB4/MTOR",9]
["GO:0019229","regulation of vasoconstriction","7/267","60/18866",2.14023038459464e-05,8.78796900516533e-05,3.14772457014049e-05,"CD38/PTGS2/HTR2A/PER2/AKT1/ACE/LEP",7]
["GO:0048747","muscle fiber development","7/267","60/18866",2.14023038459464e-05,8.78796900516533e-05,3.14772457014049e-05,"HDAC9/HDAC4/VEGFA/BCL2/NEB/DMD/GPX1",7]
["GO:0050994","regulation of lipid catabolic process","7/267","60/18866",2.14023038459464e-05,8.78796900516533e-05,3.14772457014049e-05,"CNR1/IL1B/AKT1/PRKCE/MTOR/TNF/INS",7]
["GO:0097755","positive regulation of blood vessel diameter","7/267","60/18866",2.14023038459464e-05,8.78796900516533e-05,3.14772457014049e-05,"SOD2/APOE/SOD1/NOS3/LEP/GPX1/INS",7]
["GO:0021532","neural tube patterning","6/267","41/18866",2.25372947873174e-05,9.20103948267179e-05,3.29568049607543e-05,"PAX6/PRKACA/GLI2/FGF8/SHH/PTCH1",6]
["GO:0031062","positive regulation of histone methylation","6/267","41/18866",2.25372947873174e-05,9.20103948267179e-05,3.29568049607543e-05,"BRCA1/SIRT1/KMT2A/DNMT1/CTNNB1/MECP2",6]
["GO:0033574","response to testosterone","6/267","41/18866",2.25372947873174e-05,9.20103948267179e-05,3.29568049607543e-05,"SIRT1/TSPO/DUSP1/SRD5A1/GNRH1/AR",6]
["GO:0046825","regulation of protein export from nucleus","6/267","41/18866",2.25372947873174e-05,9.20103948267179e-05,3.29568049607543e-05,"PRKACA/GSK3B/IL1B/TP53/CDK5/PTPN11",6]
["GO:0051354","negative regulation of oxidoreductase activity","6/267","41/18866",2.25372947873174e-05,9.20103948267179e-05,3.29568049607543e-05,"HDAC6/CNR1/PRKN/LRRK2/INS/HP",6]
["GO:1902042","negative regulation of extrinsic apoptotic signaling pathway via death domain receptors","6/267","41/18866",2.25372947873174e-05,9.20103948267179e-05,3.29568049607543e-05,"BRCA1/GSK3B/NOS3/FADD/BCL2L1/GPX1",6]
["GO:2000008","regulation of protein localization to cell surface","6/267","41/18866",2.25372947873174e-05,9.20103948267179e-05,3.29568049607543e-05,"TOR1A/AKT1/CTNNB1/BDNF/ERBB4/TNF",6]
["GO:0046939","nucleotide phosphorylation","10/267","135/18866",2.27227298627206e-05,9.26916586638595e-05,3.32008239050244e-05,"IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/INS",10]
["GO:0001523","retinoid metabolic process","9/267","108/18866",2.29623426325339e-05,9.35926340932584e-05,3.35235403932761e-05,"APOB/CYP2D6/TTR/APOE/CYP1A2/CYP3A4/LPL/GPC6/ADH1C",9]
["GO:0002053","positive regulation of mesenchymal cell proliferation","5/267","25/18866",2.30420055431388e-05,9.36116628778619e-05,3.35303562312474e-05,"FGFR2/FGFR1/VEGFA/SHH/CTNNB1",5]
["GO:0032104","regulation of response to extracellular stimulus","5/267","25/18866",2.30420055431388e-05,9.36116628778619e-05,3.35303562312474e-05,"OPRM1/NPY/LEP/CCK/MTOR",5]
["GO:0032107","regulation of response to nutrient levels","5/267","25/18866",2.30420055431388e-05,9.36116628778619e-05,3.35303562312474e-05,"OPRM1/NPY/LEP/CCK/MTOR",5]
["GO:0060148","positive regulation of posttranscriptional gene silencing","5/267","25/18866",2.30420055431388e-05,9.36116628778619e-05,3.35303562312474e-05,"TGFB1/MAP2K2/IL6/TP53/MAP2K1",5]
["GO:0034765","regulation of ion transmembrane transport","20/267","489/18866",2.31999961860115e-05,9.41768950867931e-05,3.37328143089718e-05,"PRKACA/DLG1/ABCB1/BAX/P2RX7/CCL2/PPARGC1A/IFNG/OPRM1/PTK2B/PER2/AKT1/DRD2/CDK5/PRKCE/CHD7/PTEN/F2/MTOR/DMD",20]
["GO:0003015","heart process","15/267","297/18866",2.32723735240657e-05,9.43939569501706e-05,3.38105627580381e-05,"TAC1/HDAC4/PRKACA/DLG1/OXT/IL2/PIK3CA/SOD1/DRD2/ACE/NOS3/ATP2A2/MTOR/DMD/GPX1",15]
["GO:0043954","cellular component maintenance","7/267","61/18866",2.3887485415621e-05,9.66533344247939e-05,3.46198393936194e-05,"DLG1/SIRT1/APOE/MTHFR/CSF1R/HDAC2/INS",7]
["GO:0061912","selective autophagy","7/267","61/18866",2.3887485415621e-05,9.66533344247939e-05,3.46198393936194e-05,"HDAC6/MAPK3/TSC2/MFN2/TP53/SQSTM1/PRKN",7]
["GO:0090342","regulation of cell aging","7/267","61/18866",2.3887485415621e-05,9.66533344247939e-05,3.46198393936194e-05,"SIRT1/KRAS/TP53/PLK2/CDKN2A/PTEN/PAWR",7]
["GO:0002040","sprouting angiogenesis","12/267","196/18866",2.39561824987087e-05,9.68528090818239e-05,3.46912883573885e-05,"HDAC9/NGFR/PTGS2/SRF/VEGFA/PTK2B/GLUL/IL10/CDH13/AKT1/PLK2/DLL1",12]
["GO:0014896","muscle hypertrophy","9/267","109/18866",2.4723549239031e-05,9.97935985048359e-05,3.57446369885663e-05,"IGF1/TNFRSF1B/TNFRSF1A/HDAC4/PDLIM5/ATP2A2/LEP/HDAC2/MTOR",9]
["GO:2000278","regulation of DNA biosynthetic process","9/267","109/18866",2.4723549239031e-05,9.97935985048359e-05,3.57446369885663e-05,"MAPK1/MAPK3/PDGFRB/DUSP1/PTK2B/MEN1/TP53/CTNNB1/ADIPOQ",9]
["GO:0048864","stem cell development","8/267","84/18866",2.49515434854268e-05,0.00010055129670923,3.60160336279174e-05,"MAPK1/HIF1A/MAPK3/EDNRA/SHH/RET/GDNF/ERBB4",8]
["GO:0097061","dendritic spine organization","8/267","84/18866",2.49515434854268e-05,0.00010055129670923,3.60160336279174e-05,"HDAC6/APOE/ADAM10/PDLIM5/CDK5/PTEN/LRRK2/INS",8]
["GO:0009886","post-embryonic animal morphogenesis","4/267","13/18866",2.53628676520407e-05,0.000101634669491685,3.64040822343644e-05,"ATRX/BAX/GNAS/FBN1",4]
["GO:0010870","positive regulation of receptor biosynthetic process","4/267","13/18866",2.53628676520407e-05,0.000101634669491685,3.64040822343644e-05,"HDAC6/HIF1A/IFNG/HDAC2",4]
["GO:0021984","adenohypophysis development","4/267","13/18866",2.53628676520407e-05,0.000101634669491685,3.64040822343644e-05,"POU1F1/FGF8/SLC6A3/DRD2",4]
["GO:0030656","regulation of vitamin metabolic process","4/267","13/18866",2.53628676520407e-05,0.000101634669491685,3.64040822343644e-05,"VDR/IFNG/IL1B/TNF",4]
["GO:0031650","regulation of heat generation","4/267","13/18866",2.53628676520407e-05,0.000101634669491685,3.64040822343644e-05,"PTGS2/CNR1/IL1B/TNF",4]
["GO:0033089","positive regulation of T cell differentiation in thymus","4/267","13/18866",2.53628676520407e-05,0.000101634669491685,3.64040822343644e-05,"GLI2/IL1A/IL1B/SHH",4]
["GO:0060601","lateral sprouting from an epithelium","4/267","13/18866",2.53628676520407e-05,0.000101634669491685,3.64040822343644e-05,"FGFR2/GLI2/SHH/AR",4]
["GO:1903038","negative regulation of leukocyte cell-cell adhesion","10/267","137/18866",2.58114256606401e-05,0.000103349196731015,3.70182013231145e-05,"DLG1/PRKAR1A/IL2/IDO1/IL10/AKT1/GNRH1/SHH/PAWR/HLA-DRB1",10]
["GO:0046006","regulation of activated T cell proliferation","6/267","42/18866",2.5983962376613e-05,0.000103790339317143,3.71762122760972e-05,"IGF1/PRKAR1A/IL2/IL18/FADD/AGER",6]
["GO:0051602","response to electrical stimulus","6/267","42/18866",2.5983962376613e-05,0.000103790339317143,3.71762122760972e-05,"REST/P2RX7/OXT/PPARGC1A/PTEN/NQO1",6]
["GO:0090278","negative regulation of peptide hormone secretion","6/267","42/18866",2.5983962376613e-05,0.000103790339317143,3.71762122760972e-05,"REST/SFRP1/DRD2/LEP/PTPN11/PRKN",6]
["GO:0002821","positive regulation of adaptive immune response","9/267","110/18866",2.65981133756052e-05,0.000105934692842781,3.79442889813917e-05,"P2RX7/SIRT1/TGFB1/IL2/IL1B/IL6/IL18/FADD/TNF",9]
["GO:0006641","triglyceride metabolic process","9/267","110/18866",2.65981133756052e-05,0.000105934692842781,3.79442889813917e-05,"ACSL4/APOB/SIRT1/GNB3/APOE/CYP2E1/LPL/PTPN11/GPX1",9]
["GO:0002260","lymphocyte homeostasis","7/267","62/18866",2.66056689014314e-05,0.000105934692842781,3.79442889813917e-05,"BAX/P2RX7/HIF1A/IL2/AKT1/FADD/BCL2",7]
["GO:0010676","positive regulation of cellular carbohydrate metabolic process","7/267","62/18866",2.66056689014314e-05,0.000105934692842781,3.79442889813917e-05,"IGF1/POU1F1/SIRT1/PPARGC1A/AKT1/PRKCE/INS",7]
["GO:0099504","synaptic vesicle cycle","12/267","199/18866",2.78374475022359e-05,0.000110750896716067,3.96693841948407e-05,"GSK3B/P2RX7/HTR2A/CNR1/TOR1A/DRD2/CDK5/CTNNB1/PTEN/SNCG/ATP2A2/LRRK2",12]
["GO:0019430","removal of superoxide radicals","5/267","26/18866",2.81999224402163e-05,0.000111836547056394,4.00582485898813e-05,"SOD2/SOD1/NOS3/NQO1/TNF",5]
["GO:0034114","regulation of heterotypic cell-cell adhesion","5/267","26/18866",2.81999224402163e-05,0.000111836547056394,4.00582485898813e-05,"IL1B/IL10/ADIPOQ/AGER/TNF",5]
["GO:0035640","exploration behavior","5/267","26/18866",2.81999224402163e-05,0.000111836547056394,4.00582485898813e-05,"APOE/PRKCE/PENK/LRRK2/DPP4",5]
["GO:0042104","positive regulation of activated T cell proliferation","5/267","26/18866",2.81999224402163e-05,0.000111836547056394,4.00582485898813e-05,"IGF1/IL2/IL18/FADD/AGER",5]
["GO:0045931","positive regulation of mitotic cell cycle","11/267","168/18866",2.8253656617621e-05,0.000111960720231573,4.01027256418865e-05,"IGF1/FGFR1/FGF8/PDGFRB/IL1A/IL1B/BRCA2/AKT1/MECP2/PTPN11/INS",11]
["GO:0001776","leukocyte homeostasis","8/267","86/18866",2.96387032079634e-05,0.000117170265334411,4.19687100473641e-05,"BAX/P2RX7/HIF1A/IL2/IL6/AKT1/FADD/BCL2",8]
["GO:0006919","activation of cysteine-type endopeptidase activity involved in apoptotic process","8/267","86/18866",2.96387032079634e-05,0.000117170265334411,4.19687100473641e-05,"NGFR/BAX/NGF/VCP/FADD/MAPT/CCK/TNF",8]
["GO:0045445","myoblast differentiation","8/267","86/18866",2.96387032079634e-05,0.000117170265334411,4.19687100473641e-05,"IGF1/REST/TGFB1/SRF/IL18/SHH/DLL1/TNF",8]
["GO:0040019","positive regulation of embryonic development","6/267","43/18866",2.98421488770608e-05,0.000117716980883192,4.21645357227578e-05,"IGF1/SHH/OTX2/CTNNB1/GDNF/AR",6]
["GO:2000648","positive regulation of stem cell proliferation","6/267","43/18866",2.98421488770608e-05,0.000117716980883192,4.21645357227578e-05,"PAX6/HIF1A/VEGFA/DRD2/SHH/CTNNB1",6]
["GO:0016125","sterol metabolic process","11/267","169/18866",2.98477263765514e-05,0.000117716980883192,4.21645357227578e-05,"PON1/APOB/CYP2D6/GNB3/APOE/CYP27A1/CYP1A2/SOD1/LBR/CYP3A4/LEP",11]
["GO:0006275","regulation of DNA replication","9/267","112/18866",3.07109739776843e-05,0.000121025961381672,4.33497651211612e-05,"GLI2/FGFR1/ATRX/SMC3/TIMELESS/RAC1/BRCA2/TP53/JUN",9]
["GO:0072655","establishment of protein localization to mitochondrion","10/267","140/18866",3.11167202184466e-05,0.000122431665918601,4.38532683431968e-05,"BAX/TSPO/MAPK8/MFN2/TP53/AKT1/BCL2/PRKN/MAPT/LRRK2",10]
["GO:0097553","calcium ion transmembrane import into cytosol","10/267","140/18866",3.11167202184466e-05,0.000122431665918601,4.38532683431968e-05,"PRKACA/BAX/P2RX7/HTR2A/PTK2B/DRD2/PRKCE/CHD7/F2/DMD",10]
["GO:0060420","regulation of heart growth","8/267","87/18866",3.22453663256296e-05,0.000126772530758952,4.54081039264357e-05,"IGF1/FGFR2/FGFR1/MAPK1/DUSP6/PTEN/ERBB4/MTOR",8]
["GO:0002437","inflammatory response to antigenic stimulus","7/267","64/18866",3.28083256349947e-05,0.000128782995200887,4.61282234805164e-05,"OPRM1/CNR1/KDM6B/IL10/HLA-DRB1/TNF/GPX1",7]
["GO:0033344","cholesterol efflux","7/267","64/18866",3.28083256349947e-05,0.000128782995200887,4.61282234805164e-05,"PON1/APOB/SIRT1/APOE/SHH/ADIPOQ/PTCH1",7]
["GO:0016042","lipid catabolic process","16/267","343/18866",3.2837658631756e-05,0.000128796881027775,4.61331971847301e-05,"APOB/CNR1/IL1B/APOE/CYP27A1/CYP1A2/AKT1/SRD5A1/CYP3A4/PRKCE/LEP/LPL/ADIPOQ/MTOR/TNF/INS",16]
["GO:0035821","modulation of process of other organism","9/267","113/18866",3.29616653132788e-05,0.000129181785643015,4.6271064502405e-05,"REST/SMARCB1/EP300/APOE/CRP/BCL2L1/JUN/CSF1R/PRKN",9]
["GO:0008584","male gonad development","10/267","141/18866",3.3080867207253e-05,0.000129547270561423,4.64019759629497e-05,"ATRX/BAX/ESR1/GATA1/SFRP1/PDGFRB/SRD5A1/AR/BCL2L1/BCL2",10]
["GO:0045687","positive regulation of glial cell differentiation","6/267","44/18866",3.4147454656827e-05,0.000133137087143307,4.76877968221782e-05,"TNFRSF1B/TGFB1/LIF/SHH/HDAC2/MTOR",6]
["GO:0060612","adipose tissue development","6/267","44/18866",3.4147454656827e-05,0.000133137087143307,4.76877968221782e-05,"SIRT1/XBP1/PPARGC1A/PIK3CA/FTO/LEP",6]
["GO:1901985","positive regulation of protein acetylation","6/267","44/18866",3.4147454656827e-05,0.000133137087143307,4.76877968221782e-05,"BRCA1/SMARCB1/MAPK3/PPARGC1A/IL1B/LIF",6]
["GO:0006706","steroid catabolic process","5/267","27/18866",3.42108717814666e-05,0.000133137087143307,4.76877968221782e-05,"APOE/CYP27A1/CYP1A2/SRD5A1/CYP3A4",5]
["GO:0033081","regulation of T cell differentiation in thymus","5/267","27/18866",3.42108717814666e-05,0.000133137087143307,4.76877968221782e-05,"GLI2/IL1A/IL1B/SOD1/SHH",5]
["GO:0042501","serine phosphorylation of STAT protein","5/267","27/18866",3.42108717814666e-05,0.000133137087143307,4.76877968221782e-05,"IFNG/LIF/CDK5/RET/IFNA1",5]
["GO:0048520","positive regulation of behavior","5/267","27/18866",3.42108717814666e-05,0.000133137087143307,4.76877968221782e-05,"HDAC4/PENK/CCK/HDAC2/MTOR",5]
["GO:0071514","genetic imprinting","5/267","27/18866",3.42108717814666e-05,0.000133137087143307,4.76877968221782e-05,"BRCA1/GNAS/PIK3CA/PRMT7/MECP2",5]
["GO:0090559","regulation of membrane permeability","8/267","88/18866",3.50410156424919e-05,0.000136050105540021,4.87311982696819e-05,"GCLC/GSK3B/BAX/MAPK8/TP53/BCL2L1/BCL2/MTOR",8]
["GO:0002244","hematopoietic progenitor cell differentiation","11/267","172/18866",3.51046766221687e-05,0.000136050105540021,4.87311982696819e-05,"REST/GATA1/SFRP1/TGFB1/SRF/KMT2A/TP53/ACE/SHH/BCL2/CSF1R",11]
["GO:1990138","neuron projection extension","11/267","172/18866",3.51046766221687e-05,0.000136050105540021,4.87311982696819e-05,"GSK3B/ADNP/SRF/VEGFA/APOE/CDK5/CTNNB1/BDNF/PRKN/MAPT/L1CAM",11]
["GO:1903054","negative regulation of extracellular matrix organization","4/267","14/18866",3.51134694919531e-05,0.000136050105540021,4.87311982696819e-05,"TNFRSF1B/TNFRSF1A/TGFB1/DPP4",4]
["GO:1904748","regulation of apoptotic process involved in development","4/267","14/18866",3.51134694919531e-05,0.000136050105540021,4.87311982696819e-05,"TNFRSF1B/TNFRSF1A/BAX/VDR",4]
["GO:0007224","smoothened signaling pathway","10/267","142/18866",3.51501374217158e-05,0.000136050105540021,4.87311982696819e-05,"CREBBP/PAX6/FGFR2/PRKACA/GLI2/SFRP1/SHH/VCP/OTX2/PTCH1",10]
["GO:0046546","development of primary male sexual characteristics","10/267","142/18866",3.51501374217158e-05,0.000136050105540021,4.87311982696819e-05,"ATRX/BAX/ESR1/GATA1/SFRP1/PDGFRB/SRD5A1/AR/BCL2L1/BCL2",10]
["GO:0098693","regulation of synaptic vesicle cycle","9/267","114/18866",3.53505141305884e-05,0.000136719687880734,4.89710330693218e-05,"GSK3B/HTR2A/CNR1/TOR1A/DRD2/CDK5/PTEN/ATP2A2/LRRK2",9]
["GO:1905953","negative regulation of lipid localization","7/267","65/18866",3.63284553156371e-05,0.000140393171355245,5.02868222105813e-05,"CRP/IL6/AKT1/SHH/LEP/PTPN11/TNF",7]
["GO:0008286","insulin receptor signaling pathway","10/267","143/18866",3.73291093066066e-05,0.00014414867963487,5.16319914616555e-05,"GSK3B/SIRT1/TSC2/PIK3CA/IL1B/AKT1/PIK3R1/LEP/PTPN11/INS",10]
["GO:0061053","somite development","8/267","89/18866",3.80363723138194e-05,0.000146733436898342,5.25578144750613e-05,"EP300/SFRP1/TP53/KDM6A/SHH/MED12/PTCH1/DLL1",8]
["GO:0043588","skin development","18/267","425/18866",3.80572402930808e-05,0.000146733436898342,5.25578144750613e-05,"PAX6/NGFR/FGFR2/GLI2/GNAS/COL1A1/VDR/SRF/STMN1/FLNB/SHH/CTNNB1/MAP2K1/BCL2/HDAC2/NF1/DLL1/TNF",18]
["GO:0090287","regulation of cellular response to growth factor stimulus","15/267","310/18866",3.81624421407881e-05,0.000147025519759996,5.26624343706945e-05,"CREBBP/NGFR/FGFR1/SIRT1/EP300/HIF1A/SFRP1/TGFB1/IL1B/MEN1/TP53/OTX2/FBN1/CTNNB1/DLL1",15]
["GO:0034198","cellular response to amino acid starvation","6/267","45/18866",3.89373681860611e-05,0.000149779876234979,5.36490053913858e-05,"MAPK1/MAPK3/MAPK8/ATF4/ATF3/MTOR",6]
["GO:1901028","regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","6/267","45/18866",3.89373681860611e-05,0.000149779876234979,5.36490053913858e-05,"GCLC/GSK3B/BAX/MAPK8/TP53/BCL2",6]
["GO:0015718","monocarboxylic acid transport","11/267","174/18866",3.90368823130779e-05,0.000150047077281908,5.37447129775287e-05,"NOS2/ACSL4/P2RX7/OXT/IL1B/APOE/AKT1/DRD2/ACE/LEP/NF1",11]
["GO:0046034","ATP metabolic process","15/267","311/18866",3.95958303211432e-05,0.000152063951477015,5.44671284133467e-05,"IGF1/HDAC4/P2RX7/TSPO/EP300/HIF1A/HTR2A/TGFB1/PPARGC1A/IFNG/LDHA/TP53/VCP/MECP2/INS",15]
["GO:0070585","protein localization to mitochondrion","10/267","144/18866",3.96225116906862e-05,0.000152063951477015,5.44671284133467e-05,"BAX/TSPO/MAPK8/MFN2/TP53/AKT1/BCL2/PRKN/MAPT/LRRK2",10]
["GO:0046626","regulation of insulin receptor signaling pathway","7/267","66/18866",4.01529337165976e-05,0.000153981258100593,5.51538801717999e-05,"SIRT1/TSC2/IL1B/PIK3R1/LEP/PTPN11/INS",7]
["GO:0060964","regulation of gene silencing by miRNA","9/267","116/18866",4.05700702143504e-05,0.000155461520015542,5.56840887782699e-05,"ESR1/TGFB1/MAP2K2/IL6/TP53/MAP2K1/LIN28B/TNF/NEAT1",9]
["GO:0007269","neurotransmitter secretion","11/267","175/18866",4.11413574957312e-05,0.000157033736653963,5.62472342490189e-05,"GSK3B/P2RX7/HTR2A/CNR1/DRD2/CDK5/SNCG/ATP2A2/PRKN/LRRK2/NF1",11]
["GO:0099643","signal release from synapse","11/267","175/18866",4.11413574957312e-05,0.000157033736653963,5.62472342490189e-05,"GSK3B/P2RX7/HTR2A/CNR1/DRD2/CDK5/SNCG/ATP2A2/PRKN/LRRK2/NF1",11]
["GO:0002360","T cell lineage commitment","5/267","28/18866",4.11690689525412e-05,0.000157033736653963,5.62472342490189e-05,"IL6/TP53/SHH/BCL2/MTOR",5]
["GO:0033598","mammary gland epithelial cell proliferation","5/267","28/18866",4.11690689525412e-05,0.000157033736653963,5.62472342490189e-05,"BAX/ESR1/MAPK1/BRCA2/GPX1",5]
["GO:0071450","cellular response to oxygen radical","5/267","28/18866",4.11690689525412e-05,0.000157033736653963,5.62472342490189e-05,"SOD2/SOD1/NOS3/NQO1/TNF",5]
["GO:0071451","cellular response to superoxide","5/267","28/18866",4.11690689525412e-05,0.000157033736653963,5.62472342490189e-05,"SOD2/SOD1/NOS3/NQO1/TNF",5]
["GO:0014902","myotube differentiation","9/267","117/18866",4.34150864916107e-05,0.000165474447979093,5.92705760942118e-05,"IGF1/HDAC9/HDAC4/XBP1/SHH/BCL2/BDNF/MTOR/GPX1",9]
["GO:0005978","glycogen biosynthetic process","6/267","46/18866",4.4251293827122e-05,0.000167574457242967,6.00227693203752e-05,"IGF1/GSK3B/PER2/AKT1/MTOR/INS",6]
["GO:0009250","glucan biosynthetic process","6/267","46/18866",4.4251293827122e-05,0.000167574457242967,6.00227693203752e-05,"IGF1/GSK3B/PER2/AKT1/MTOR/INS",6]
["GO:0010874","regulation of cholesterol efflux","6/267","46/18866",4.4251293827122e-05,0.000167574457242967,6.00227693203752e-05,"PON1/SIRT1/APOE/SHH/ADIPOQ/PTCH1",6]
["GO:0017144","drug metabolic process","6/267","46/18866",4.4251293827122e-05,0.000167574457242967,6.00227693203752e-05,"CYP2D6/CYP2E1/CYP1A2/CYP3A4/CYP2C19/CYP2B6",6]
["GO:0050798","activated T cell proliferation","6/267","46/18866",4.4251293827122e-05,0.000167574457242967,6.00227693203752e-05,"IGF1/PRKAR1A/IL2/IL18/FADD/AGER",6]
["GO:0051646","mitochondrion localization","6/267","46/18866",4.4251293827122e-05,0.000167574457242967,6.00227693203752e-05,"HDAC6/HIF1A/MFN2/ALB/MAPT/LRRK2",6]
["GO:1900744","regulation of p38MAPK cascade","6/267","46/18866",4.4251293827122e-05,0.000167574457242967,6.00227693203752e-05,"DLG1/VEGFA/DUSP1/IL1B/LEP/AGER",6]
["GO:0032890","regulation of organic acid transport","7/267","67/18866",4.43016790628314e-05,0.000167574457242967,6.00227693203752e-05,"P2RX7/OXT/IL1B/PER2/AKT1/LEP/CCK",7]
["GO:0050918","positive chemotaxis","7/267","67/18866",4.43016790628314e-05,0.000167574457242967,6.00227693203752e-05,"TSC2/FGF8/VEGFA/CDH13/GDNF/CXCL8/AGER",7]
["GO:0071300","cellular response to retinoic acid","7/267","67/18866",4.43016790628314e-05,0.000167574457242967,6.00227693203752e-05,"FGFR2/COL1A1/CREB1/PTK2B/RET/LEP/HDAC2",7]
["GO:0034620","cellular response to unfolded protein","10/267","146/18866",4.45722936238444e-05,0.000168470448193683,6.03437004397877e-05,"BAX/XBP1/EP300/CCL2/ATF4/PIK3R1/ATF3/VCP/CXCL8/PRKN",10]
["GO:0033273","response to vitamin","8/267","91/18866",4.46712477189351e-05,0.000168716747247083,6.04319212313646e-05,"PTGS2/TSPO/SFRP1/COL1A1/VDR/LEP/MTHFR/PENK",8]
["GO:0015918","sterol transport","9/267","118/18866",4.64268884323572e-05,0.000175082669141057,6.27121032330854e-05,"PON1/APOB/SIRT1/TSPO/APOE/SHH/LEP/ADIPOQ/PTCH1",9]
["GO:0050868","negative regulation of T cell activation","9/267","118/18866",4.64268884323572e-05,0.000175082669141057,6.27121032330854e-05,"DLG1/PRKAR1A/IL2/IDO1/IL10/GNRH1/SHH/PAWR/HLA-DRB1",9]
["GO:0006089","lactate metabolic process","4/267","15/18866",4.73501992646798e-05,0.000177759056337253,6.36707467753786e-05,"HIF1A/PER2/LDHA/TP53",4]
["GO:0048308","organelle inheritance","4/267","15/18866",4.73501992646798e-05,0.000177759056337253,6.36707467753786e-05,"MAPK1/MAPK3/MAP2K2/MAP2K1",4]
["GO:0048313","Golgi inheritance","4/267","15/18866",4.73501992646798e-05,0.000177759056337253,6.36707467753786e-05,"MAPK1/MAPK3/MAP2K2/MAP2K1",4]
["GO:0048569","post-embryonic animal organ development","4/267","15/18866",4.73501992646798e-05,0.000177759056337253,6.36707467753786e-05,"BAX/VEGFA/LDHA/FBN1",4]
["GO:1901550","regulation of endothelial cell development","4/267","15/18866",4.73501992646798e-05,0.000177759056337253,6.36707467753786e-05,"TNFRSF1A/VEGFA/IL1B/TNF",4]
["GO:1903140","regulation of establishment of endothelial barrier","4/267","15/18866",4.73501992646798e-05,0.000177759056337253,6.36707467753786e-05,"TNFRSF1A/VEGFA/IL1B/TNF",4]
["GO:0009953","dorsal/ventral pattern formation","8/267","92/18866",4.83343907022433e-05,0.000181181390973199,6.48965780015105e-05,"PAX6/PRKACA/GLI2/SFRP1/FGF8/SHH/CTNNB1/PTCH1",8]
["GO:0045582","positive regulation of T cell differentiation","8/267","92/18866",4.83343907022433e-05,0.000181181390973199,6.48965780015105e-05,"GLI2/XBP1/IL2/IFNG/IL1A/IL1B/IL18/SHH",8]
["GO:0016239","positive regulation of macroautophagy","7/267","68/18866",4.87954745369943e-05,0.000182498729860084,6.53684299139391e-05,"HDAC6/SIRT1/HIF1A/MAPK3/TSC2/MFN2/PRKN",7]
["GO:0042446","hormone biosynthetic process","7/267","68/18866",4.87954745369943e-05,0.000182498729860084,6.53684299139391e-05,"TG/REST/TSPO/HIF1A/PPARGC1A/TPO/SRD5A1",7]
["GO:0051148","negative regulation of muscle cell differentiation","7/267","68/18866",4.87954745369943e-05,0.000182498729860084,6.53684299139391e-05,"HDAC4/XBP1/DNMT1/SHH/MECP2/BDNF/DLL1",7]
["GO:0001958","endochondral ossification","5/267","29/18866",4.91740614725288e-05,0.000182547278016607,6.5385819167933e-05,"FGFR3/GNAS/COL1A1/COL2A1/INPPL1",5]
["GO:0007263","nitric oxide mediated signal transduction","5/267","29/18866",4.91740614725288e-05,0.000182547278016607,6.5385819167933e-05,"NOS2/VEGFA/APOE/NOS3/INS",5]
["GO:0008209","androgen metabolic process","5/267","29/18866",4.91740614725288e-05,0.000182547278016607,6.5385819167933e-05,"ESR1/PPARGC1A/SRD5A1/CYP3A4/SHH",5]
["GO:0032373","positive regulation of sterol transport","5/267","29/18866",4.91740614725288e-05,0.000182547278016607,6.5385819167933e-05,"PON1/SIRT1/APOE/ADIPOQ/PTCH1",5]
["GO:0032376","positive regulation of cholesterol transport","5/267","29/18866",4.91740614725288e-05,0.000182547278016607,6.5385819167933e-05,"PON1/SIRT1/APOE/ADIPOQ/PTCH1",5]
["GO:0033032","regulation of myeloid cell apoptotic process","5/267","29/18866",4.91740614725288e-05,0.000182547278016607,6.5385819167933e-05,"SIRT1/CDKN2A/BCL2/PTEN/ADIPOQ",5]
["GO:0035116","embryonic hindlimb morphogenesis","5/267","29/18866",4.91740614725288e-05,0.000182547278016607,6.5385819167933e-05,"GNAS/FGF8/SHH/CTNNB1/CHD7",5]
["GO:0036075","replacement ossification","5/267","29/18866",4.91740614725288e-05,0.000182547278016607,6.5385819167933e-05,"FGFR3/GNAS/COL1A1/COL2A1/INPPL1",5]
["GO:0045671","negative regulation of osteoclast differentiation","5/267","29/18866",4.91740614725288e-05,0.000182547278016607,6.5385819167933e-05,"SFRP1/PIK3R1/FBN1/CTNNB1/NF1",5]
["GO:0060441","epithelial tube branching involved in lung morphogenesis","5/267","29/18866",4.91740614725288e-05,0.000182547278016607,6.5385819167933e-05,"FGFR2/KRAS/SHH/CTNNB1/TNF",5]
["GO:0031396","regulation of protein ubiquitination","12/267","211/18866",4.93555808719465e-05,0.000183085003932859,6.55784248857723e-05,"GCLC/BRCA1/TSPO/PER2/AKT1/SQSTM1/CDK5/PRKCE/PTEN/PRKN/LRRK2/MTOR",12]
["GO:0046486","glycerolipid metabolic process","18/267","434/18866",4.99226373212033e-05,0.00018505102312158,6.62826247870311e-05,"PON1/ACSL4/APOB/SIRT1/HTR2A/GNB3/PDGFRB/PIK3CA/APOE/CYP2E1/PIK3R1/INPPL1/MECP2/PTEN/LPL/PTPN11/CSF1R/GPX1",18]
["GO:0014075","response to amine","6/267","47/18866",5.01305773018021e-05,0.000185408868494739,6.64107998719389e-05,"HDAC9/OXT/PPP1R1B/SOD1/DRD2/HDAC2",6]
["GO:0048599","oocyte development","6/267","47/18866",5.01305773018021e-05,0.000185408868494739,6.64107998719389e-05,"IGF1/PTK2B/BRCA2/KMT2D/CTNNB1/BCL2",6]
["GO:0070849","response to epidermal growth factor","6/267","47/18866",5.01305773018021e-05,0.000185408868494739,6.64107998719389e-05,"MAPK1/MAPK3/COL1A1/AKT1/ERBB4/PTPN11",6]
["GO:0060147","regulation of posttranscriptional gene silencing","9/267","120/18866",5.29822873195038e-05,0.000195521910770219,7.00331466998223e-05,"ESR1/TGFB1/MAP2K2/IL6/TP53/MAP2K1/LIN28B/TNF/NEAT1",9]
["GO:0060966","regulation of gene silencing by RNA","9/267","120/18866",5.29822873195038e-05,0.000195521910770219,7.00331466998223e-05,"ESR1/TGFB1/MAP2K2/IL6/TP53/MAP2K1/LIN28B/TNF/NEAT1",9]
["GO:1903364","positive regulation of cellular protein catabolic process","10/267","149/18866",5.29824044206102e-05,0.000195521910770219,7.00331466998223e-05,"GCLC/GSK3B/PTK2B/APOE/AKT1/PLK2/VCP/PTEN/PRKN/LRRK2",10]
["GO:0008544","epidermis development","19/267","477/18866",5.31197336102581e-05,0.000195883921651417,7.01628138100198e-05,"PAX6/NGFR/FGFR2/GLI2/FGFR1/VDR/FLNB/SOD1/SHH/CTNNB1/MAP2K1/BCL2/ATP2A2/PTCH1/HLA-DRB1/HDAC2/NF1/DLL1/TNF",19]
["GO:1901796","regulation of signal transduction by p53 class mediator","11/267","180/18866",5.31934236877038e-05,0.000196010896289819,7.0208294306008e-05,"BRCA1/SIRT1/EP300/TBP/TP53/AKT1/CDK5/BCL2/EHMT1/PRKN/HDAC2",11]
["GO:0042698","ovulation cycle","7/267","69/18866",5.36559836114003e-05,0.000197569562073541,7.07665860547812e-05,"ESR1/SIRT1/ADNP/OPRM1/GNRH1/NOS3/LEP",7]
["GO:0010950","positive regulation of endopeptidase activity","11/267","181/18866",5.59370104870399e-05,0.000205816870568747,7.3720653777668e-05,"NGFR/REST/BAX/SIRT1/NGF/VCP/FADD/MAPT/CCK/AGER/TNF",11]
["GO:0010948","negative regulation of cell cycle process","16/267","359/18866",5.65893024001275e-05,0.000207864937075687,7.44542418526129e-05,"BRCA1/ATRX/BAX/EP300/L3MBTL2/CCL2/PRKAR1A/DUSP1/LIF/MEN1/TP53/PLK2/CDKN2A/BCL2/PTEN/EHMT1",16]
["GO:0055023","positive regulation of cardiac muscle tissue growth","6/267","48/18866",5.66185288249417e-05,0.000207864937075687,7.44542418526129e-05,"IGF1/FGFR2/FGFR1/MAPK1/ERBB4/MTOR",6]
["GO:1990928","response to amino acid starvation","6/267","48/18866",5.66185288249417e-05,0.000207864937075687,7.44542418526129e-05,"MAPK1/MAPK3/MAPK8/ATF4/ATF3/MTOR",6]
["GO:0000303","response to superoxide","5/267","30/18866",5.83306986136963e-05,0.00021274300816522,7.62014970163931e-05,"SOD2/SOD1/NOS3/NQO1/TNF",5]
["GO:0003401","axis elongation","5/267","30/18866",5.83306986136963e-05,0.00021274300816522,7.62014970163931e-05,"FGFR2/ESR1/SFRP1/SHH/MED12",5]
["GO:0005979","regulation of glycogen biosynthetic process","5/267","30/18866",5.83306986136963e-05,0.00021274300816522,7.62014970163931e-05,"IGF1/GSK3B/AKT1/MTOR/INS",5]
["GO:0010962","regulation of glucan biosynthetic process","5/267","30/18866",5.83306986136963e-05,0.00021274300816522,7.62014970163931e-05,"IGF1/GSK3B/AKT1/MTOR/INS",5]
["GO:0019098","reproductive behavior","5/267","30/18866",5.83306986136963e-05,0.00021274300816522,7.62014970163931e-05,"HDAC4/OXT/PPP1R1B/PTEN/HDAC2",5]
["GO:0048147","negative regulation of fibroblast proliferation","5/267","30/18866",5.83306986136963e-05,0.00021274300816522,7.62014970163931e-05,"BAX/SFRP1/TP53/PAWR/NF1",5]
["GO:0060055","angiogenesis involved in wound healing","5/267","30/18866",5.83306986136963e-05,0.00021274300816522,7.62014970163931e-05,"XBP1/SRF/VEGFA/TNF/GPX1",5]
["GO:0070168","negative regulation of biomineral tissue development","5/267","30/18866",5.83306986136963e-05,0.00021274300816522,7.62014970163931e-05,"HIF1A/GATA1/TGFB1/PTK2B/NOS3",5]
["GO:0110150","negative regulation of biomineralization","5/267","30/18866",5.83306986136963e-05,0.00021274300816522,7.62014970163931e-05,"HIF1A/GATA1/TGFB1/PTK2B/NOS3",5]
["GO:0002534","cytokine production involved in inflammatory response","7/267","70/18866",5.89057648692557e-05,0.000214526975924284,7.68404887042616e-05,"NOS2/IL17A/IDO1/IL6/LEP/F2/TNF",7]
["GO:0009880","embryonic pattern specification","7/267","70/18866",5.89057648692557e-05,0.000214526975924284,7.68404887042616e-05,"FGFR2/KDM6A/SHH/CTNNB1/ERBB4/PTCH1/DLL1",7]
["GO:2001056","positive regulation of cysteine-type endopeptidase activity","10/267","151/18866",5.93106059111597e-05,0.000215843917867653,7.73121984372106e-05,"NGFR/REST/BAX/SIRT1/NGF/VCP/FADD/MAPT/CCK/TNF",10]
["GO:0042752","regulation of circadian rhythm","9/267","122/18866",6.03018191888422e-05,0.000219291320619001,7.8547008703065e-05,"GSK3B/MAPK8/PPARGC1A/TIMELESS/CREB1/PER2/TP53/DRD2/MTOR",9]
["GO:0045638","negative regulation of myeloid cell differentiation","8/267","95/18866",6.08579541264321e-05,0.000221152667360463,7.9213716433623e-05,"SFRP1/PTK2B/PIK3R1/FBN1/CTNNB1/ADIPOQ/NF1/DLL1",8]
["GO:0006986","response to unfolded protein","11/267","183/18866",6.1790495658223e-05,0.000224215076178421,8.03106273893214e-05,"BAX/XBP1/EP300/CCL2/MFN2/ATF4/PIK3R1/ATF3/VCP/CXCL8/PRKN",11]
["GO:0071347","cellular response to interleukin-1","11/267","183/18866",6.1790495658223e-05,0.000224215076178421,8.03106273893214e-05,"VRK2/HIF1A/MAPK3/SFRP1/CCL2/IL17A/IL1A/IL1B/IL6/SQSTM1/CXCL8",11]
["GO:0032225","regulation of synaptic transmission, dopaminergic","4/267","16/18866",6.24327103393867e-05,0.000225725215586211,8.08515376855962e-05,"PTGS2/TOR1A/DRD2/GDNF",4]
["GO:0034116","positive regulation of heterotypic cell-cell adhesion","4/267","16/18866",6.24327103393867e-05,0.000225725215586211,8.08515376855962e-05,"IL1B/IL10/AGER/TNF",4]
["GO:0036124","histone H3-K9 trimethylation","4/267","16/18866",6.24327103393867e-05,0.000225725215586211,8.08515376855962e-05,"ATRX/SIRT1/SMARCB1/MECP2",4]
["GO:0071599","otic vesicle development","4/267","16/18866",6.24327103393867e-05,0.000225725215586211,8.08515376855962e-05,"FGFR2/FGF8/COL2A1/HESX1",4]
["GO:1903358","regulation of Golgi organization","4/267","16/18866",6.24327103393867e-05,0.000225725215586211,8.08515376855962e-05,"MAPK1/MAPK3/MAP2K2/MAP2K1",4]
["GO:0006090","pyruvate metabolic process","10/267","152/18866",6.27087519356832e-05,0.000226559188433333,8.11502548089921e-05,"IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/INS",10]
["GO:0006163","purine nucleotide metabolic process","18/267","442/18866",6.31138443310849e-05,0.000227857863156259,8.16154214853394e-05,"NOS2/IGF1/HDAC4/ACSL4/DLG1/P2RX7/EP300/HIF1A/HTR2A/TGFB1/PPARGC1A/IFNG/LDHA/NOS3/VCP/LRRK2/GPX1/INS",18]
["GO:0002067","glandular epithelial cell differentiation","6/267","49/18866",6.37604438987269e-05,0.000229363037742322,8.21545534536152e-05,"PAX6/FGFR2/GSK3B/FGF8/MEN1/DLL1",6]
["GO:0003254","regulation of membrane depolarization","6/267","49/18866",6.37604438987269e-05,0.000229363037742322,8.21545534536152e-05,"GCLC/P2RX7/TSPO/BCL2/CCK/LRRK2",6]
["GO:0006111","regulation of gluconeogenesis","6/267","49/18866",6.37604438987269e-05,0.000229363037742322,8.21545534536152e-05,"SIRT1/EP300/PPARGC1A/LEP/ADIPOQ/INS",6]
["GO:0031279","regulation of cyclase activity","6/267","49/18866",6.37604438987269e-05,0.000229363037742322,8.21545534536152e-05,"NOS2/MAPK3/MAPK8/DRD2/NOS3/NF1",6]
["GO:0070231","T cell apoptotic process","6/267","49/18866",6.37604438987269e-05,0.000229363037742322,8.21545534536152e-05,"BAX/HIF1A/IDO1/TP53/AKT1/FADD",6]
["GO:0048675","axon extension","9/267","123/18866",6.42698171637754e-05,0.000231028939595918,8.27512556259743e-05,"GSK3B/ADNP/SRF/VEGFA/APOE/CDK5/BDNF/MAPT/L1CAM",9]
["GO:0050792","regulation of viral process","12/267","217/18866",6.46991420556975e-05,0.000232404903801509,8.32441062874897e-05,"REST/SMARCB1/EP300/APOE/CRP/CXCL8/BCL2/JUN/CSF1R/PRKN/HLA-DRB1/TNF",12]
["GO:0007416","synapse assembly","11/267","184/18866",6.49091994738268e-05,0.000232991828161623,8.34543341829291e-05,"ADNP/OXT/NTRK2/DRD2/PDLIM5/CDK5/MECP2/PTEN/BDNF/ERBB4/GPC6",11]
["GO:0000305","response to oxygen radical","5/267","31/18866",6.87490900486764e-05,0.000246067531622252,8.81378637937757e-05,"SOD2/SOD1/NOS3/NQO1/TNF",5]
["GO:0021772","olfactory bulb development","5/267","31/18866",6.87490900486764e-05,0.000246067531622252,8.81378637937757e-05,"SRF/CHD7/ERBB4/CSF1R/LRRK2",5]
["GO:0045940","positive regulation of steroid metabolic process","5/267","31/18866",6.87490900486764e-05,0.000246067531622252,8.81378637937757e-05,"PPARGC1A/IFNG/IL1B/APOE/TNF",5]
["GO:0060261","positive regulation of transcription initiation from RNA polymerase II promoter","5/267","31/18866",6.87490900486764e-05,0.000246067531622252,8.81378637937757e-05,"ESR1/SRF/CREB1/TP53/MED12",5]
["GO:0051250","negative regulation of lymphocyte activation","10/267","154/18866",7.00042423340283e-05,0.000250380502846564,8.9682708283452e-05,"DLG1/SFRP1/PRKAR1A/IL2/IDO1/IL10/GNRH1/SHH/PAWR/HLA-DRB1",10]
["GO:0030516","regulation of axon extension","8/267","97/18866",7.06209544261925e-05,0.000252224910908426,9.0343348821701e-05,"GSK3B/ADNP/SRF/VEGFA/APOE/CDK5/MAPT/L1CAM",8]
["GO:0032651","regulation of interleukin-1 beta production","8/267","97/18866",7.06209544261925e-05,0.000252224910908426,9.0343348821701e-05,"IGF1/P2RX7/IFNG/IL17A/IL6/LPL/AGER/TNF",8]
["GO:0002449","lymphocyte mediated immunity","16/267","366/18866",7.10465251566486e-05,0.000253563473986524,9.08228029352891e-05,"TNFRSF1B/DLG1/P2RX7/TGFB1/IL2/IL1B/CRP/IL6/IL10/IL18/FADD/LEP/HLA-DQB1/HLA-DRB1/AGER/TNF",16]
["GO:0021695","cerebellar cortex development","6/267","50/18866",7.16036217665991e-05,0.000255004909757938,9.13391045735055e-05,"GLI2/RERE/CDK5/MAP2K1/PTPN11/DLL1",6]
["GO:0031648","protein destabilization","6/267","50/18866",7.16036217665991e-05,0.000255004909757938,9.13391045735055e-05,"CREBBP/HDAC6/SIRT1/XBP1/EP300/PRKN",6]
["GO:1904707","positive regulation of vascular associated smooth muscle cell proliferation","6/267","50/18866",7.16036217665991e-05,0.000255004909757938,9.13391045735055e-05,"IGF1/MFN2/DNMT1/IL10/JUN/TNF",6]
["GO:0030968","endoplasmic reticulum unfolded protein response","9/267","125/18866",7.28681136438441e-05,0.000259138526655067,9.28197069132488e-05,"BAX/XBP1/EP300/CCL2/ATF4/PIK3R1/ATF3/VCP/CXCL8",9]
["GO:0043500","muscle adaptation","9/267","125/18866",7.28681136438441e-05,0.000259138526655067,9.28197069132488e-05,"IGF1/TNFRSF1B/TNFRSF1A/HDAC4/PPARGC1A/IL1B/NOS3/ATP2A2/MTOR",9]
["GO:0099003","vesicle-mediated transport in synapse","12/267","220/18866",7.38065023017355e-05,0.000262288872592573,9.39481156850711e-05,"GSK3B/P2RX7/HTR2A/CNR1/TOR1A/DRD2/CDK5/CTNNB1/PTEN/SNCG/ATP2A2/LRRK2",12]
["GO:0050821","protein stabilization","11/267","187/18866",7.50885208533361e-05,0.000266655038848298,9.55120138727394e-05,"IGF1/GRN/EP300/BAG1/PPARGC1A/CREB1/TP53/PIK3R1/DVL3/PTEN/PRKN",11]
["GO:0002709","regulation of T cell mediated immunity","7/267","73/18866",7.72300505779776e-05,0.00027387048475557,9.80964832027392e-05,"TNFRSF1B/P2RX7/IL1B/IL6/IL18/FADD/AGER",7]
["GO:0005977","glycogen metabolic process","7/267","73/18866",7.72300505779776e-05,0.00027387048475557,9.80964832027392e-05,"IGF1/GSK3B/POMC/PER2/AKT1/MTOR/INS",7]
["GO:0034401","chromatin organization involved in regulation of transcription","10/267","156/18866",7.800893594868e-05,0.000276436208084996,9.90154885337173e-05,"ARID1B/SIRT1/DNMT1/CDKN2A/KMT2D/CTNNB1/MECP2/MTHFR/HDAC2/HOTAIR",10]
["GO:0045861","negative regulation of proteolysis","16/267","369/18866",7.81760811059919e-05,0.000276832037561856,9.91572689802764e-05,"NGFR/PTGS2/HDAC6/VEGFA/NGF/IL10/TP53/AKT1/SHH/CDK5/F2/LRRK2/SERPINA3/TNF/GPX1/INS",16]
["GO:0071478","cellular response to radiation","11/267","188/18866",7.87721326988288e-05,0.000278745045049789,9.98424808499461e-05,"CREBBP/PTGS2/BAX/SIRT1/EP300/SFRP1/ATF4/TP53/PIK3R1/BCL2L1/MC1R",11]
["GO:0002762","negative regulation of myeloid leukocyte differentiation","6/267","51/18866",8.01973815300605e-05,0.000282692049091978,0.000101256241139125,"SFRP1/PIK3R1/FBN1/CTNNB1/ADIPOQ/NF1",6]
["GO:0032873","negative regulation of stress-activated MAPK cascade","6/267","51/18866",8.01973815300605e-05,0.000282692049091978,0.000101256241139125,"DLG1/SFRP1/DUSP1/MEN1/AKT1/PRKN",6]
["GO:0070303","negative regulation of stress-activated protein kinase signaling cascade","6/267","51/18866",8.01973815300605e-05,0.000282692049091978,0.000101256241139125,"DLG1/SFRP1/DUSP1/MEN1/AKT1/PRKN",6]
["GO:0071675","regulation of mononuclear cell migration","6/267","51/18866",8.01973815300605e-05,0.000282692049091978,0.000101256241139125,"MAPK1/MAPK3/DUSP1/CSF1R/AGER/TNF",6]
["GO:0010743","regulation of macrophage derived foam cell differentiation","5/267","32/18866",8.05445541821914e-05,0.000282692049091978,0.000101256241139125,"APOB/CRP/IL18/LPL/ADIPOQ",5]
["GO:0071295","cellular response to vitamin","5/267","32/18866",8.05445541821914e-05,0.000282692049091978,0.000101256241139125,"SFRP1/COL1A1/VDR/LEP/PENK",5]
["GO:1902235","regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","5/267","32/18866",8.05445541821914e-05,0.000282692049091978,0.000101256241139125,"SIRT1/XBP1/BCL2L1/PRKN/LRRK2",5]
["GO:0002460","adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","16/267","370/18866",8.06883944678402e-05,0.000282692049091978,0.000101256241139125,"TNFRSF1B/DLG1/P2RX7/TGFB1/IL2/IL1B/CRP/IL6/IL10/IL18/FADD/HLA-DQB1/HLA-DRB1/MTOR/AGER/TNF",16]
["GO:0008340","determination of adult lifespan","4/267","17/18866",8.07368039265292e-05,0.000282692049091978,0.000101256241139125,"POU1F1/TP53/LEP/LRRK2",4]
["GO:0030540","female genitalia development","4/267","17/18866",8.07368039265292e-05,0.000282692049091978,0.000101256241139125,"BAX/ESR1/SRD5A1/CHD7",4]
["GO:0046851","negative regulation of bone remodeling","4/267","17/18866",8.07368039265292e-05,0.000282692049091978,0.000101256241139125,"CD38/P2RX7/SFRP1/IL6",4]
["GO:0055089","fatty acid homeostasis","4/267","17/18866",8.07368039265292e-05,0.000282692049091978,0.000101256241139125,"SIRT1/XBP1/APOE/INS",4]
["GO:0060644","mammary gland epithelial cell differentiation","4/267","17/18866",8.07368039265292e-05,0.000282692049091978,0.000101256241139125,"HIF1A/AKT1/ERBB4/PTCH1",4]
["GO:1903209","positive regulation of oxidative stress-induced cell death","4/267","17/18866",8.07368039265292e-05,0.000282692049091978,0.000101256241139125,"REST/HDAC6/SOD1/PAWR",4]
["GO:2000811","negative regulation of anoikis","4/267","17/18866",8.07368039265292e-05,0.000282692049091978,0.000101256241139125,"PIK3CA/NTRK2/BCL2/TLE1",4]
["GO:0051017","actin filament bundle assembly","10/267","157/18866",8.22942884799415e-05,0.000287943505522318,0.000103137237581544,"TAC1/SFRP1/SRF/STMN1/PTK2B/RAC1/PIK3R1/PAWR/PRKN/MTOR",10]
["GO:1903052","positive regulation of proteolysis involved in cellular protein catabolic process","9/267","127/18866",8.24139914823554e-05,0.000288160405792297,0.000103214928150171,"GCLC/GSK3B/PTK2B/AKT1/PLK2/VCP/PTEN/PRKN/LRRK2",9]
["GO:0006073","cellular glucan metabolic process","7/267","74/18866",8.4280897360221e-05,0.000294070244947298,0.000105331747850245,"IGF1/GSK3B/POMC/PER2/AKT1/MTOR/INS",7]
["GO:0032024","positive regulation of insulin secretion","7/267","74/18866",8.4280897360221e-05,0.000294070244947298,0.000105331747850245,"CD38/ACSL4/HIF1A/GLUL/RAC1/PRKCE/HLA-DRB1",7]
["GO:0044042","glucan metabolic process","7/267","74/18866",8.4280897360221e-05,0.000294070244947298,0.000105331747850245,"IGF1/GSK3B/POMC/PER2/AKT1/MTOR/INS",7]
["GO:1903707","negative regulation of hemopoiesis","10/267","158/18866",8.67777904259531e-05,0.000302570885193285,0.000108376555376135,"SFRP1/IL2/PTK2B/PIK3R1/SHH/FBN1/CTNNB1/ADIPOQ/NF1/DLL1",10]
["GO:0009994","oocyte differentiation","6/267","52/18866",8.95930759357898e-05,0.000311300089177034,0.00011150323115768,"IGF1/PTK2B/BRCA2/KMT2D/CTNNB1/BCL2",6]
["GO:0038066","p38MAPK cascade","6/267","52/18866",8.95930759357898e-05,0.000311300089177034,0.00011150323115768,"DLG1/VEGFA/DUSP1/IL1B/LEP/AGER",6]
["GO:0060421","positive regulation of heart growth","6/267","52/18866",8.95930759357898e-05,0.000311300089177034,0.00011150323115768,"IGF1/FGFR2/FGFR1/MAPK1/ERBB4/MTOR",6]
["GO:0071622","regulation of granulocyte chemotaxis","6/267","52/18866",8.95930759357898e-05,0.000311300089177034,0.00011150323115768,"MAPK1/MAPK3/RAC1/CXCL8/CSF1R/DPP4",6]
["GO:1903557","positive regulation of tumor necrosis factor superfamily cytokine production","6/267","52/18866",8.95930759357898e-05,0.000311300089177034,0.00011150323115768,"IFNG/PIK3R1/FADD/LEP/PTPN11/HDAC2",6]
["GO:1903362","regulation of cellular protein catabolic process","13/267","260/18866",9.02561866634219e-05,0.000313386050076819,0.000112250392461133,"GCLC/PRKACA/GSK3B/PTK2B/APOE/AKT1/PLK2/SHH/VCP/PTEN/PRKN/LRRK2/GPX1",13]
["GO:2000058","regulation of ubiquitin-dependent protein catabolic process","10/267","159/18866",9.14667957813493e-05,0.000317368805654119,0.000113676958437886,"GCLC/GSK3B/PTK2B/AKT1/PLK2/SHH/VCP/PTEN/PRKN/LRRK2",10]
["GO:0001707","mesoderm formation","7/267","75/18866",9.18477168219375e-05,0.000318248195761231,0.000113991943373003,"FGFR2/PRKACA/FGFR1/PRKAR1A/SRF/KDM6B/KDM6A",7]
["GO:0030858","positive regulation of epithelial cell differentiation","7/267","75/18866",9.18477168219375e-05,0.000318248195761231,0.000113991943373003,"PAX6/VDR/LIF/CTNNB1/GDNF/ADIPOQ/PTCH1",7]
["GO:0071482","cellular response to light stimulus","9/267","129/18866",9.29890670897868e-05,0.000321979481261654,0.000115328436371668,"CREBBP/PTGS2/BAX/SIRT1/EP300/ATF4/TP53/PIK3R1/MC1R",9]
["GO:0002861","regulation of inflammatory response to antigenic stimulus","5/267","33/18866",9.38375567998061e-05,0.000323347771636599,0.000115818538377008,"CNR1/IL10/HLA-DRB1/TNF/GPX1",5]
["GO:0010464","regulation of mesenchymal cell proliferation","5/267","33/18866",9.38375567998061e-05,0.000323347771636599,0.000115818538377008,"FGFR2/FGFR1/VEGFA/SHH/CTNNB1",5]
["GO:0021696","cerebellar cortex morphogenesis","5/267","33/18866",9.38375567998061e-05,0.000323347771636599,0.000115818538377008,"GLI2/CDK5/MAP2K1/PTPN11/DLL1",5]
["GO:0021988","olfactory lobe development","5/267","33/18866",9.38375567998061e-05,0.000323347771636599,0.000115818538377008,"SRF/CHD7/ERBB4/CSF1R/LRRK2",5]
["GO:0042755","eating behavior","5/267","33/18866",9.38375567998061e-05,0.000323347771636599,0.000115818538377008,"OXT/OPRM1/LEP/CCK/MTOR",5]
["GO:0048011","neurotrophin TRK receptor signaling pathway","5/267","33/18866",9.38375567998061e-05,0.000323347771636599,0.000115818538377008,"NGFR/NGF/NTRK2/BDNF/PTPN11",5]
["GO:1902003","regulation of amyloid-beta formation","5/267","33/18866",9.38375567998061e-05,0.000323347771636599,0.000115818538377008,"IGF1/IFNG/APOE/NTRK2/TNF",5]
["GO:0042632","cholesterol homeostasis","8/267","101/18866",9.40724542701396e-05,0.000323933630462625,0.000116028384613406,"HDAC9/APOB/SIRT1/XBP1/VDR/APOE/IL18/LPL",8]
["GO:0061136","regulation of proteasomal protein catabolic process","11/267","193/18866",9.96008195356289e-05,0.000342626532990893,0.00012272391443843,"GCLC/PRKACA/GSK3B/APOE/AKT1/PLK2/SHH/VCP/PRKN/LRRK2/GPX1",11]
["GO:0018023","peptidyl-lysine trimethylation","6/267","53/18866",9.98441028443318e-05,0.000342626532990893,0.00012272391443843,"ATRX/SIRT1/SMARCB1/KMT2A/KMT2D/MECP2",6]
["GO:0032964","collagen biosynthetic process","6/267","53/18866",9.98441028443318e-05,0.000342626532990893,0.00012272391443843,"TGFB1/COL1A1/PDGFRB/IL6/F2/HDAC2",6]
["GO:0045668","negative regulation of osteoblast differentiation","6/267","53/18866",9.98441028443318e-05,0.000342626532990893,0.00012272391443843,"HDAC4/SFRP1/MEN1/PTCH1/TNF/TWIST2",6]
["GO:2000772","regulation of cellular senescence","6/267","53/18866",9.98441028443318e-05,0.000342626532990893,0.00012272391443843,"SIRT1/KRAS/TP53/PLK2/CDKN2A/PAWR",6]
["GO:0043502","regulation of muscle adaptation","8/267","102/18866",0.000100846752922903,0.000345592201334288,0.000123786174342386,"IGF1/TNFRSF1B/TNFRSF1A/HDAC4/PPARGC1A/NOS3/ATP2A2/MTOR",8]
["GO:0055092","sterol homeostasis","8/267","102/18866",0.000100846752922903,0.000345592201334288,0.000123786174342386,"HDAC9/APOB/SIRT1/XBP1/VDR/APOE/IL18/LPL",8]
["GO:0061572","actin filament bundle organization","10/267","161/18866",0.000101491732935903,0.000347563938648123,0.000124492422394123,"TAC1/SFRP1/SRF/STMN1/PTK2B/RAC1/PIK3R1/PAWR/PRKN/MTOR",10]
["GO:0032740","positive regulation of interleukin-17 production","4/267","18/18866",0.000102653078446514,0.00035010028735208,0.000125400906155182,"TGFB1/IL2/IL6/IL18",4]
["GO:0051023","regulation of immunoglobulin secretion","4/267","18/18866",0.000102653078446514,0.00035010028735208,0.000125400906155182,"XBP1/IL2/IL6/TNF",4]
["GO:0051571","positive regulation of histone H3-K4 methylation","4/267","18/18866",0.000102653078446514,0.00035010028735208,0.000125400906155182,"BRCA1/KMT2A/DNMT1/CTNNB1",4]
["GO:1900221","regulation of amyloid-beta clearance","4/267","18/18866",0.000102653078446514,0.00035010028735208,0.000125400906155182,"IFNG/SRF/APOE/TNF",4]
["GO:1905276","regulation of epithelial tube formation","4/267","18/18866",0.000102653078446514,0.00035010028735208,0.000125400906155182,"SFRP1/DVL3/GDNF/FZD2",4]
["GO:2000641","regulation of early endosome to late endosome transport","4/267","18/18866",0.000102653078446514,0.00035010028735208,0.000125400906155182,"MAPK1/MAPK3/MAP2K2/MAP2K1",4]
["GO:0046902","regulation of mitochondrial membrane permeability","7/267","77/18866",0.000108643096445768,0.000368890575901636,0.000132131318257535,"GCLC/GSK3B/BAX/MAPK8/TP53/BCL2L1/BCL2",7]
["GO:0048332","mesoderm morphogenesis","7/267","77/18866",0.000108643096445768,0.000368890575901636,0.000132131318257535,"FGFR2/PRKACA/FGFR1/PRKAR1A/SRF/KDM6B/KDM6A",7]
["GO:0032148","activation of protein kinase B activity","5/267","34/18866",0.000108753640642341,0.000368890575901636,0.000132131318257535,"IGF1/AKT1/IL18/MTOR/INS",5]
["GO:0033198","response to ATP","5/267","34/18866",0.000108753640642341,0.000368890575901636,0.000132131318257535,"PTGS2/P2RX7/IL1B/SOD1/PTEN",5]
["GO:0042311","vasodilation","5/267","34/18866",0.000108753640642341,0.000368890575901636,0.000132131318257535,"SOD2/APOE/SOD1/NOS3/GPX1",5]
["GO:0046685","response to arsenic-containing substance","5/267","34/18866",0.000108753640642341,0.000368890575901636,0.000132131318257535,"GCLC/ATF4/ATF3/VCP/PTEN",5]
["GO:0048566","embryonic digestive tract development","5/267","34/18866",0.000108753640642341,0.000368890575901636,0.000132131318257535,"FGFR2/GLI2/SHH/CXCL8/TNF",5]
["GO:0070050","neuron cellular homeostasis","5/267","34/18866",0.000108753640642341,0.000368890575901636,0.000132131318257535,"CNR1/IL6/CDK5/CALB2/PRKN",5]
["GO:0030522","intracellular receptor signaling pathway","13/267","265/18866",0.000109254305913572,0.000370085990112934,0.000132559498498292,"BRCA1/ESR1/HDAC6/SIRT1/EP300/SFRP1/VDR/NR3C1/ESR2/NR3C2/KMT2D/AR/LEP",13]
["GO:0032412","regulation of ion transmembrane transporter activity","13/267","265/18866",0.000109254305913572,0.000370085990112934,0.000132559498498292,"PRKACA/DLG1/ABCB1/CCL2/PPARGC1A/IFNG/OPRM1/PTK2B/DRD2/CDK5/PRKCE/PTEN/DMD",13]
["GO:0042476","odontogenesis","9/267","132/18866",0.000110972144703465,0.000375395608742818,0.00013446132780715,"NGFR/FGFR2/GLI2/BAX/FGF8/COL1A1/SHH/CTNNB1/HDAC2",9]
["GO:1902807","negative regulation of cell cycle G1/S phase transition","9/267","132/18866",0.000110972144703465,0.000375395608742818,0.00013446132780715,"BAX/EP300/CCL2/MEN1/TP53/PLK2/CDKN2A/BCL2/PTEN",9]
["GO:0002456","T cell mediated immunity","8/267","104/18866",0.000115609677112969,0.000390818630890355,0.000139985633335662,"TNFRSF1B/DLG1/P2RX7/IL1B/IL6/IL18/FADD/AGER",8]
["GO:0006909","phagocytosis","16/267","382/18866",0.000116848604227579,0.000394739567596957,0.000141390056678767,"P2RX7/MAPK1/MAPK3/CCL2/IFNG/PIK3CA/IL1B/CRP/RAC1/SOD1/PIK3R1/PRKCE/PTEN/LEP/ADIPOQ/TNF",16]
["GO:0043903","regulation of symbiotic process","12/267","231/18866",0.000117305771974454,0.000396016037504021,0.000141847269908257,"REST/SMARCB1/EP300/APOE/CRP/CXCL8/BCL2/JUN/CSF1R/PRKN/HLA-DRB1/TNF",12]
["GO:0000271","polysaccharide biosynthetic process","7/267","78/18866",0.000117931036231137,0.000397589239636778,0.000142410768368956,"IGF1/GSK3B/TGFB1/PER2/AKT1/MTOR/INS",7]
["GO:0072332","intrinsic apoptotic signaling pathway by p53 class mediator","7/267","78/18866",0.000117931036231137,0.000397589239636778,0.000142410768368956,"BAX/SIRT1/EP300/BRCA2/TP53/BCL2/PRKN",7]
["GO:0052547","regulation of peptidase activity","18/267","466/18866",0.000123035886072348,0.000414018967858045,0.000148295661587447,"GRN/NGFR/PTGS2/REST/BAX/SIRT1/MAPK3/VEGFA/NGF/AKT1/VCP/FADD/MAPT/CCK/SERPINA3/AGER/TNF/GPX1",18]
["GO:0001954","positive regulation of cell-matrix adhesion","6/267","55/18866",0.000123136023887282,0.000414018967858045,0.000148295661587447,"GSK3B/SFRP1/VEGFA/PTK2B/RAC1/CDH13",6]
["GO:0032720","negative regulation of tumor necrosis factor production","6/267","55/18866",0.000123136023887282,0.000414018967858045,0.000148295661587447,"IGF1/TSPO/POMC/IL10/ADIPOQ/MC1R",6]
["GO:0097345","mitochondrial outer membrane permeabilization","6/267","55/18866",0.000123136023887282,0.000414018967858045,0.000148295661587447,"GCLC/GSK3B/BAX/MAPK8/TP53/BCL2",6]
["GO:0002824","positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","8/267","105/18866",0.000123634926291315,0.000414858324578316,0.000148596307137057,"P2RX7/TGFB1/IL2/IL1B/IL6/IL18/FADD/TNF",8]
["GO:0045621","positive regulation of lymphocyte differentiation","8/267","105/18866",0.000123634926291315,0.000414858324578316,0.000148596307137057,"GLI2/XBP1/IL2/IFNG/IL1A/IL1B/IL18/SHH",8]
["GO:1902106","negative regulation of leukocyte differentiation","8/267","105/18866",0.000123634926291315,0.000414858324578316,0.000148596307137057,"SFRP1/IL2/PIK3R1/SHH/FBN1/CTNNB1/ADIPOQ/NF1",8]
["GO:0014904","myotube cell development","5/267","35/18866",0.000125423346491426,0.000419449945768045,0.000150240960051421,"IGF1/HDAC9/HDAC4/BCL2/GPX1",5]
["GO:0045922","negative regulation of fatty acid metabolic process","5/267","35/18866",0.000125423346491426,0.000419449945768045,0.000150240960051421,"BRCA1/SIRT1/CNR1/AKT1/INS",5]
["GO:0070884","regulation of calcineurin-NFAT signaling cascade","5/267","35/18866",0.000125423346491426,0.000419449945768045,0.000150240960051421,"IGF1/ERBB3/GSK3B/MTOR/TNF",5]
["GO:0098801","regulation of renal system process","5/267","35/18866",0.000125423346491426,0.000419449945768045,0.000150240960051421,"TAC1/COMT/OXT/DRD2/ADIPOQ",5]
["GO:1901030","positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","5/267","35/18866",0.000125423346491426,0.000419449945768045,0.000150240960051421,"GSK3B/BAX/MAPK8/TP53/BCL2",5]
["GO:0021675","nerve development","7/267","79/18866",0.000127853727702924,0.000426435312238276,0.000152743018224004,"NGFR/ERBB3/NGF/RET/CTNNB1/CHD7/BDNF",7]
["GO:0043407","negative regulation of MAP kinase activity","7/267","79/18866",0.000127853727702924,0.000426435312238276,0.000152743018224004,"SFRP1/DUSP1/IL1B/APOE/DUSP6/ADIPOQ/NF1",7]
["GO:0070373","negative regulation of ERK1 and ERK2 cascade","7/267","79/18866",0.000127853727702924,0.000426435312238276,0.000152743018224004,"DLG1/DUSP1/LIF/DUSP6/ATF3/PTEN/ADIPOQ",7]
["GO:0099601","regulation of neurotransmitter receptor activity","7/267","79/18866",0.000127853727702924,0.000426435312238276,0.000152743018224004,"DLG1/CCL2/PPARGC1A/IFNG/OPRM1/PTK2B/CDK5",7]
["GO:0002076","osteoblast development","4/267","19/18866",0.000128585631202494,0.000427733548696902,0.000153208027920359,"HDAC4/GLI2/MEN1/SHH",4]
["GO:0032930","positive regulation of superoxide anion generation","4/267","19/18866",0.000128585631202494,0.000427733548696902,0.000153208027920359,"TGFB1/CRP/SOD1/MAPT",4]
["GO:0070989","oxidative demethylation","4/267","19/18866",0.000128585631202494,0.000427733548696902,0.000153208027920359,"CYP2D6/CYP1A2/FTO/CYP3A4",4]
["GO:2000696","regulation of epithelial cell differentiation involved in kidney development","4/267","19/18866",0.000128585631202494,0.000427733548696902,0.000153208027920359,"LIF/CTNNB1/GDNF/ADIPOQ",4]
["GO:0002708","positive regulation of lymphocyte mediated immunity","8/267","106/18866",0.000132114703505696,0.00043830479375677,0.000156994496419778,"P2RX7/TGFB1/IL2/IL1B/IL6/IL18/FADD/TNF",8]
["GO:0007218","neuropeptide signaling pathway","8/267","106/18866",0.000132114703505696,0.00043830479375677,0.000156994496419778,"TAC1/OPRM1/POMC/NPY/GRPR/NTS/SORCS3/PENK",8]
["GO:0030038","contractile actin filament bundle assembly","8/267","106/18866",0.000132114703505696,0.00043830479375677,0.000156994496419778,"TAC1/SFRP1/SRF/STMN1/PTK2B/RAC1/PIK3R1/MTOR",8]
["GO:0043149","stress fiber assembly","8/267","106/18866",0.000132114703505696,0.00043830479375677,0.000156994496419778,"TAC1/SFRP1/SRF/STMN1/PTK2B/RAC1/PIK3R1/MTOR",8]
["GO:0031295","T cell costimulation","6/267","56/18866",0.000136294010394338,0.000451808744560887,0.000161831418092476,"PIK3CA/RAC1/AKT1/PIK3R1/PTPN11/DPP4",6]
["GO:0030258","lipid modification","13/267","271/18866",0.000136530337421611,0.000451808744560887,0.000161831418092476,"PPARGC1A/CNR1/PIK3CA/APOE/CYP2E1/AKT1/PIK3R1/CYP3A4/INPPL1/PTEN/LEP/ADIPOQ/MTOR",13]
["GO:0016052","carbohydrate catabolic process","11/267","200/18866",0.000136547044971436,0.000451808744560887,0.000161831418092476,"IGF1/HDAC4/P2RX7/EP300/HIF1A/HTR2A/PPARGC1A/IFNG/LDHA/TP53/INS",11]
["GO:0031032","actomyosin structure organization","11/267","200/18866",0.000136547044971436,0.000451808744560887,0.000161831418092476,"TAC1/SFRP1/PRKAR1A/SRF/PDGFRB/STMN1/PTK2B/RAC1/PIK3R1/NEB/MTOR",11]
["GO:0002697","regulation of immune effector process","18/267","470/18866",0.000136835478372256,0.000452463273849453,0.00016206586110454,"NOS2/TNFRSF1B/GRN/P2RX7/XBP1/TGFB1/IL2/IFNG/IL1B/IL6/IL10/IL18/FADD/LEP/F2/AGER/TNF/INS",18]
["GO:0002312","B cell activation involved in immune response","7/267","80/18866",0.00013844337231066,0.000456570513835619,0.000163537015612746,"XBP1/TGFB1/IL2/PTK2B/IL6/IL10/DLL1",7]
["GO:0003151","outflow tract morphogenesis","7/267","80/18866",0.00013844337231066,0.000456570513835619,0.000163537015612746,"FGFR2/HIF1A/FGF8/VEGFA/CTNNB1/JUN/FZD2",7]
["GO:0055021","regulation of cardiac muscle tissue growth","7/267","80/18866",0.00013844337231066,0.000456570513835619,0.000163537015612746,"IGF1/FGFR2/FGFR1/MAPK1/PTEN/ERBB4/MTOR",7]
["GO:2000300","regulation of synaptic vesicle exocytosis","7/267","80/18866",0.00013844337231066,0.000456570513835619,0.000163537015612746,"GSK3B/HTR2A/CNR1/DRD2/CDK5/ATP2A2/LRRK2",7]
["GO:0030330","DNA damage response, signal transduction by p53 class mediator","8/267","107/18866",0.00014106871158962,0.000464921502948497,0.000166528220247188,"BRCA1/ATRX/BAX/SIRT1/EP300/BRCA2/TP53/PLK2",8]
["GO:1904062","regulation of cation transmembrane transport","15/267","349/18866",0.000143846952661899,0.000472962339974967,0.000169408332848613,"PRKACA/DLG1/BAX/CCL2/PPARGC1A/IFNG/OPRM1/PTK2B/DRD2/CDK5/PRKCE/CHD7/PTEN/F2/DMD",15]
["GO:0031128","developmental induction","5/267","36/18866",0.000143982126329251,0.000472962339974967,0.000169408332848613,"FGFR1/FGF8/CTNNB1/GDNF/AR",5]
["GO:0043368","positive T cell selection","5/267","36/18866",0.000143982126329251,0.000472962339974967,0.000169408332848613,"SRF/IL6/SHH/BCL2/MTOR",5]
["GO:0046676","negative regulation of insulin secretion","5/267","36/18866",0.000143982126329251,0.000472962339974967,0.000169408332848613,"REST/SFRP1/DRD2/PTPN11/PRKN",5]
["GO:0106056","regulation of calcineurin-mediated signaling","5/267","36/18866",0.000143982126329251,0.000472962339974967,0.000169408332848613,"IGF1/ERBB3/GSK3B/MTOR/TNF",5]
["GO:0006260","DNA replication","13/267","273/18866",0.000146840154620322,0.000482033459578742,0.000172657477905759,"NFIX/BRCA1/GLI2/FGFR1/ATRX/SMC3/TIMELESS/REV1/RAC1/BRCA2/POLG/TP53/JUN",13]
["GO:0046942","carboxylic acid transport","15/267","350/18866",0.000148414233919956,0.000486880597872759,0.000174393653385438,"NOS2/ACSL4/P2RX7/OXT/IL1B/APOE/PER2/AKT1/NTRK2/DRD2/ACE/LEP/BDNF/CCK/NF1",15]
["GO:0021766","hippocampus development","7/267","81/18866",0.000149733191699045,0.000490562878053367,0.000175712593380769,"GSK3B/SRF/KDM6B/SRD5A1/CDK5/ALK/PTEN",7]
["GO:0051279","regulation of release of sequestered calcium ion into cytosol","7/267","81/18866",0.000149733191699045,0.000490562878053367,0.000175712593380769,"PRKACA/BAX/PTK2B/PRKCE/CHD7/F2/DMD",7]
["GO:0002062","chondrocyte differentiation","8/267","108/18866",0.000150517221106187,0.000490635649521496,0.000175738659077871,"COL11A1/FGFR3/GLI2/FGFR1/TGFB1/COL2A1/CTNNB1/PTPN11",8]
["GO:0008593","regulation of Notch signaling pathway","8/267","108/18866",0.000150517221106187,0.000490635649521496,0.000175738659077871,"CREBBP/NOTCH3/EP300/ADAM10/AKT1/PRKCI/NOS3/DLL1",8]
["GO:0032615","interleukin-12 production","6/267","57/18866",0.000150541521142986,0.000490635649521496,0.000175738659077871,"IFNG/IL17A/IDO1/IL10/LEP/AGER",6]
["GO:0045840","positive regulation of mitotic nuclear division","6/267","57/18866",0.000150541521142986,0.000490635649521496,0.000175738659077871,"IGF1/FGF8/PDGFRB/IL1A/IL1B/INS",6]
["GO:0051568","histone H3-K4 methylation","6/267","57/18866",0.000150541521142986,0.000490635649521496,0.000175738659077871,"BRCA1/KMT2A/DNMT1/KDM6A/KMT2D/CTNNB1",6]
["GO:0061005","cell differentiation involved in kidney development","6/267","57/18866",0.000150541521142986,0.000490635649521496,0.000175738659077871,"LIF/SHH/CTNNB1/GDNF/ADIPOQ/PTCH1",6]
["GO:0097479","synaptic vesicle localization","6/267","57/18866",0.000150541521142986,0.000490635649521496,0.000175738659077871,"TOR1A/CDK5/CTNNB1/PTEN/PRKN/LRRK2",6]
["GO:1903556","negative regulation of tumor necrosis factor superfamily cytokine production","6/267","57/18866",0.000150541521142986,0.000490635649521496,0.000175738659077871,"IGF1/TSPO/POMC/IL10/ADIPOQ/MC1R",6]
["GO:0002705","positive regulation of leukocyte mediated immunity","9/267","138/18866",0.000155754842403342,0.000506634480859861,0.00018146921120746,"NOS2/P2RX7/TGFB1/IL2/IL1B/IL6/IL18/FADD/TNF",9]
["GO:0006638","neutral lipid metabolic process","9/267","138/18866",0.000155754842403342,0.000506634480859861,0.00018146921120746,"ACSL4/APOB/SIRT1/GNB3/APOE/CYP2E1/LPL/PTPN11/GPX1",9]
["GO:0006639","acylglycerol metabolic process","9/267","138/18866",0.000155754842403342,0.000506634480859861,0.00018146921120746,"ACSL4/APOB/SIRT1/GNB3/APOE/CYP2E1/LPL/PTPN11/GPX1",9]
["GO:0002902","regulation of B cell apoptotic process","4/267","20/18866",0.000158950810832957,0.000515017130752078,0.000184471756279376,"BAX/IL2/IL10/PTEN",4]
["GO:0019373","epoxygenase P450 pathway","4/267","20/18866",0.000158950810832957,0.000515017130752078,0.000184471756279376,"CYP2E1/CYP1A2/CYP2C19/CYP2B6",4]
["GO:0033141","positive regulation of peptidyl-serine phosphorylation of STAT protein","4/267","20/18866",0.000158950810832957,0.000515017130752078,0.000184471756279376,"IFNG/LIF/RET/IFNA1",4]
["GO:0097709","connective tissue replacement","4/267","20/18866",0.000158950810832957,0.000515017130752078,0.000184471756279376,"HIF1A/TGFB1/IL1A/AGER",4]
["GO:1902236","negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","4/267","20/18866",0.000158950810832957,0.000515017130752078,0.000184471756279376,"XBP1/BCL2L1/PRKN/LRRK2",4]
["GO:2000774","positive regulation of cellular senescence","4/267","20/18866",0.000158950810832957,0.000515017130752078,0.000184471756279376,"SIRT1/KRAS/CDKN2A/PAWR",4]
["GO:0043618","regulation of transcription from RNA polymerase II promoter in response to stress","8/267","109/18866",0.000160481076303586,0.000519638141364334,0.000186126936063753,"CREBBP/EP300/HIF1A/VEGFA/ATF4/TP53/ATF3/JUN",8]
["GO:0015849","organic acid transport","15/267","353/18866",0.000162880950951001,0.000527067134217984,0.000188787894849917,"NOS2/ACSL4/P2RX7/OXT/IL1B/APOE/PER2/AKT1/NTRK2/DRD2/ACE/LEP/BDNF/CCK/NF1",15]
["GO:0060260","regulation of transcription initiation from RNA polymerase II promoter","5/267","37/18866",0.000164570249113761,0.000531156595879127,0.000190252681416854,"ESR1/SRF/CREB1/TP53/MED12",5]
["GO:0070897","transcription preinitiation complex assembly","5/267","37/18866",0.000164570249113761,0.000531156595879127,0.000190252681416854,"ESR1/SMARCB1/TBP/CREB1/TP53",5]
["GO:0090218","positive regulation of lipid kinase activity","5/267","37/18866",0.000164570249113761,0.000531156595879127,0.000190252681416854,"FGFR3/TGFB1/PDGFRB/PTK2B/F2",5]
["GO:0090322","regulation of superoxide metabolic process","5/267","37/18866",0.000164570249113761,0.000531156595879127,0.000190252681416854,"TGFB1/CRP/SOD1/MAPT/TNF",5]
["GO:0031294","lymphocyte costimulation","6/267","58/18866",0.000165942271677569,0.000535238864655105,0.000191714891595396,"PIK3CA/RAC1/AKT1/PIK3R1/PTPN11/DPP4",6]
["GO:0060968","regulation of gene silencing","9/267","140/18866",0.00017367724933622,0.00055982602061701,0.000200521658538438,"ESR1/TGFB1/MAP2K2/IL6/TP53/MAP2K1/LIN28B/TNF/NEAT1",9]
["GO:0002718","regulation of cytokine production involved in immune response","7/267","83/18866",0.000174551387407986,0.000561194512123679,0.00020101183258628,"TNFRSF1B/TGFB1/IL1B/IL6/IL10/IL18/TNF",7]
["GO:0014855","striated muscle cell proliferation","7/267","83/18866",0.000174551387407986,0.000561194512123679,0.00020101183258628,"FGFR2/FGFR1/MAPK1/PRKAR1A/SHH/PTEN/ERBB4",7]
["GO:0055013","cardiac muscle cell development","7/267","83/18866",0.000174551387407986,0.000561194512123679,0.00020101183258628,"IGF1/SRF/VEGFA/PDGFRB/PDLIM5/NEB/MTOR",7]
["GO:2000243","positive regulation of reproductive process","7/267","83/18866",0.000174551387407986,0.000561194512123679,0.00020101183258628,"HDAC4/OXT/VEGFA/SHH/CTNNB1/AR/HDAC2",7]
["GO:0002429","immune response-activating cell surface receptor signaling pathway","18/267","481/18866",0.000182039842523887,0.000584146033987256,0.000209232738833177,"CD38/CREBBP/PRKACA/BAX/MAPK1/EP300/MAPK3/PIK3CA/KRAS/RAC1/PIK3R1/PRKCE/BCL2/PAWR/HLA-DQB1/PAX5/HLA-DRB1/HLA-DQA1",18]
["GO:0002757","immune response-activating signal transduction","18/267","481/18866",0.000182039842523887,0.000584146033987256,0.000209232738833177,"CD38/CREBBP/PRKACA/BAX/MAPK1/EP300/MAPK3/PIK3CA/KRAS/RAC1/PIK3R1/PRKCE/BCL2/PAWR/HLA-DQB1/PAX5/HLA-DRB1/HLA-DQA1",18]
["GO:0051149","positive regulation of muscle cell differentiation","8/267","111/18866",0.000182041103321484,0.000584146033987256,0.000209232738833177,"IGF1/SIRT1/TGFB1/SOD2/SHH/CTNNB1/BCL2/MTOR",8]
["GO:0001889","liver development","9/267","141/18866",0.000183263366299559,0.000587436730840846,0.000210411419291977,"XBP1/PIK3CA/KRAS/IL6/IL10/SRD5A1/JUN/PTCH1/NF1",9]
["GO:0099173","postsynapse organization","10/267","173/18866",0.000183301908001209,0.000587436730840846,0.000210411419291977,"DLG1/HDAC6/APOE/ADAM10/PDLIM5/CDK5/GDNF/PTEN/LRRK2/INS",10]
["GO:0051954","positive regulation of amine transport","5/267","38/18866",0.000187332699689484,0.000599584724070254,0.000214762656391656,"P2RX7/OXT/DRD2/GDNF/CCK",5]
["GO:1903523","negative regulation of blood circulation","5/267","38/18866",0.000187332699689484,0.000599584724070254,0.000214762656391656,"TAC1/IL2/ATP2A2/LEP/AGER",5]
["GO:0003205","cardiac chamber development","10/267","174/18866",0.000192098555909022,0.000614051273786011,0.000219944367200909,"COL11A1/FGFR2/HIF1A/TGFB1/FGF8/SRF/TP53/NOS3/CHD7/FZD2",10]
["GO:0010469","regulation of signaling receptor activity","10/267","174/18866",0.000192098555909022,0.000614051273786011,0.000219944367200909,"DLG1/CCL2/PPARGC1A/IFNG/OPRM1/PTK2B/IL10/ESR2/CDK5/PTEN",10]
["GO:1902905","positive regulation of supramolecular fiber organization","11/267","208/18866",0.000192476423076058,0.000614398519109674,0.000220068745499981,"TAC1/DLG1/SFRP1/PTK2B/APOE/RAC1/MECP2/PRKCE/MAPT/MTOR/GPX1",11]
["GO:0005976","polysaccharide metabolic process","8/267","112/18866",0.000193681882501777,0.000614398519109674,0.000220068745499981,"IGF1/GSK3B/TGFB1/POMC/PER2/AKT1/MTOR/INS",8]
["GO:0010893","positive regulation of steroid biosynthetic process","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"PPARGC1A/IFNG/IL1B/TNF",4]
["GO:0030220","platelet formation","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"EP300/GATA1/SRF/PTPN11",4]
["GO:0030728","ovulation","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"PTGS2/SIRT1/NOS3/LEP",4]
["GO:0035813","regulation of renal sodium excretion","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"TAC1/COMT/OXT/DRD2",4]
["GO:0036499","PERK-mediated unfolded protein response","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"CCL2/ATF4/ATF3/CXCL8",4]
["GO:0046716","muscle cell cellular homeostasis","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"HIF1A/SRF/SOD1/DMD",4]
["GO:0046827","positive regulation of protein export from nucleus","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"PRKACA/GSK3B/IL1B/TP53",4]
["GO:0048305","immunoglobulin secretion","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"XBP1/IL2/IL6/TNF",4]
["GO:0072111","cell proliferation involved in kidney development","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"PDGFRB/IL6R/SHH/PTCH1",4]
["GO:0090312","positive regulation of protein deacetylation","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"IFNG/VEGFA/TP53/LRRK2",4]
["GO:0098780","response to mitochondrial depolarisation","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"HDAC6/MFN2/SQSTM1/PRKN",4]
["GO:0140467","integrated stress response signaling","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"CCL2/ATF4/ATF3/CXCL8",4]
["GO:1903599","positive regulation of autophagy of mitochondrion","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"HDAC6/HIF1A/MFN2/PRKN",4]
["GO:1904886","beta-catenin destruction complex disassembly","4/267","21/18866",0.000194176019057694,0.000614398519109674,0.000220068745499981,"GSK3B/DVL3/CTNNB1/FZD2",4]
["GO:0035904","aorta development","6/267","60/18866",0.000200468681621042,0.000633506409704976,0.000226912918104031,"NGFR/FGF8/SRF/PDGFRB/CHD7/LEP",6]
["GO:0043966","histone H3 acetylation","6/267","60/18866",0.000200468681621042,0.000633506409704976,0.000226912918104031,"BRCA1/SIRT1/SMARCB1/KMT2A/LIF/BRCA2",6]
["GO:0043154","negative regulation of cysteine-type endopeptidase activity involved in apoptotic process","7/267","85/18866",0.000202594764685243,0.000639820151849094,0.000229174410067065,"NGFR/PTGS2/VEGFA/NGF/AKT1/TNF/GPX1",7]
["GO:0032963","collagen metabolic process","8/267","113/18866",0.000205927232382805,0.000649933420535616,0.000232796837992139,"P2RX7/HIF1A/TGFB1/COL1A1/PDGFRB/IL6/F2/HDAC2",8]
["GO:0010737","protein kinase A signaling","5/267","39/18866",0.000212419071333684,0.000668310285550778,0.000239379167708639,"PRKACA/PRKAR1A/ADIPOQ/LRRK2/MC1R",5]
["GO:0032660","regulation of interleukin-17 production","5/267","39/18866",0.000212419071333684,0.000668310285550778,0.000239379167708639,"TGFB1/IL2/IFNG/IL6/IL18",5]
["GO:0038179","neurotrophin signaling pathway","5/267","39/18866",0.000212419071333684,0.000668310285550778,0.000239379167708639,"NGFR/NGF/NTRK2/BDNF/PTPN11",5]
["GO:0055090","acylglycerol homeostasis","5/267","39/18866",0.000212419071333684,0.000668310285550778,0.000239379167708639,"SIRT1/XBP1/APOE/IL18/LPL",5]
["GO:0070328","triglyceride homeostasis","5/267","39/18866",0.000212419071333684,0.000668310285550778,0.000239379167708639,"SIRT1/XBP1/APOE/IL18/LPL",5]
["GO:0002700","regulation of production of molecular mediator of immune response","9/267","144/18866",0.000214703338655153,0.000674646802961093,0.000241648817445665,"TNFRSF1B/XBP1/TGFB1/IL2/IL1B/IL6/IL10/IL18/TNF",9]
["GO:0061008","hepaticobiliary system development","9/267","144/18866",0.000214703338655153,0.000674646802961093,0.000241648817445665,"XBP1/PIK3CA/KRAS/IL6/IL10/SRD5A1/JUN/PTCH1/NF1",9]
["GO:0014910","regulation of smooth muscle cell migration","7/267","86/18866",0.00021791998532247,0.000683893454880636,0.000244960835663023,"IGF1/HDAC4/PPARGC1A/PDGFRB/ACE/BCL2/ADIPOQ",7]
["GO:0034637","cellular carbohydrate biosynthetic process","7/267","86/18866",0.00021791998532247,0.000683893454880636,0.000244960835663023,"IGF1/GSK3B/PER2/AKT1/LEP/MTOR/INS",7]
["GO:0006470","protein dephosphorylation","14/267","323/18866",0.000219091879024375,0.000687139291437628,0.000246123447806409,"DLG1/GSK3B/TGFB1/PDGFRB/DUSP1/PPP1R1B/DUSP6/DRD2/BCL2/PTEN/PTPN11/LRRK2/MTOR/TNF",14]
["GO:0021872","forebrain generation of neurons","6/267","61/18866",0.000219732084843451,0.000687850971550691,0.000246378361424863,"PAX6/FGFR2/FGFR1/FGF8/ERBB4/CSF1R",6]
["GO:0042733","embryonic digit morphogenesis","6/267","61/18866",0.000219732084843451,0.000687850971550691,0.000246378361424863,"CREBBP/GLI2/BAX/SHH/CTNNB1/HDAC2",6]
["GO:1902110","positive regulation of mitochondrial membrane permeability involved in apoptotic process","6/267","61/18866",0.000219732084843451,0.000687850971550691,0.000246378361424863,"GCLC/GSK3B/BAX/MAPK8/TP53/BCL2",6]
["GO:0043620","regulation of DNA-templated transcription in response to stress","8/267","115/18866",0.000232327424809334,0.000726823829619678,0.000260337880722239,"CREBBP/EP300/HIF1A/VEGFA/ATF4/TP53/ATF3/JUN",8]
["GO:0032436","positive regulation of proteasomal ubiquitin-dependent protein catabolic process","7/267","87/18866",0.000234166514484694,0.000730579745272461,0.000261683195888541,"GCLC/GSK3B/AKT1/PLK2/VCP/PRKN/LRRK2",7]
["GO:0002313","mature B cell differentiation involved in immune response","4/267","22/18866",0.00023469856026778,0.000730579745272461,0.000261683195888541,"XBP1/PTK2B/IL6/DLL1",4]
["GO:0010888","negative regulation of lipid storage","4/267","22/18866",0.00023469856026778,0.000730579745272461,0.000261683195888541,"CRP/IL6/LEP/TNF",4]
["GO:0032928","regulation of superoxide anion generation","4/267","22/18866",0.00023469856026778,0.000730579745272461,0.000261683195888541,"TGFB1/CRP/SOD1/MAPT",4]
["GO:0036344","platelet morphogenesis","4/267","22/18866",0.00023469856026778,0.000730579745272461,0.000261683195888541,"EP300/GATA1/SRF/PTPN11",4]
["GO:0043369","CD4-positive or CD8-positive, alpha-beta T cell lineage commitment","4/267","22/18866",0.00023469856026778,0.000730579745272461,0.000261683195888541,"IL6/SHH/BCL2/MTOR",4]
["GO:0055093","response to hyperoxia","4/267","22/18866",0.00023469856026778,0.000730579745272461,0.000261683195888541,"COL1A1/PDGFRB/POLG/HDAC2",4]
["GO:0071379","cellular response to prostaglandin stimulus","4/267","22/18866",0.00023469856026778,0.000730579745272461,0.000261683195888541,"APOB/SFRP1/AKT1/PRKCE",4]
["GO:0046631","alpha-beta T cell activation","9/267","146/18866",0.000238057047222145,0.000740572483975183,0.000265262451700557,"IL2/IFNG/IL6/IL18/SHH/BCL2/MTOR/AGER/INS",9]
["GO:0021587","cerebellum morphogenesis","5/267","40/18866",0.000239983452417702,0.000745172498707454,0.000266910111061584,"GLI2/CDK5/MAP2K1/PTPN11/DLL1",5]
["GO:0042417","dopamine metabolic process","5/267","40/18866",0.000239983452417702,0.000745172498707454,0.000266910111061584,"COMT/SLC6A3/DRD2/PRKN/MAOA",5]
["GO:0045740","positive regulation of DNA replication","5/267","40/18866",0.000239983452417702,0.000745172498707454,0.000266910111061584,"GLI2/FGFR1/ATRX/RAC1/JUN",5]
["GO:0060997","dendritic spine morphogenesis","6/267","62/18866",0.000240424200837239,0.000745613686198966,0.000267068138099032,"HDAC6/ADAM10/PDLIM5/CDK5/PTEN/LRRK2",6]
["GO:2001244","positive regulation of intrinsic apoptotic signaling pathway","6/267","62/18866",0.000240424200837239,0.000745613686198966,0.000267068138099032,"BAX/SIRT1/TP53/SOD1/BCL2L1/BCL2",6]
["GO:1903828","negative regulation of cellular protein localization","8/267","116/18866",0.000246531673297852,0.000764079853988934,0.0002736824547898,"GSK3B/TGFB1/CDK5/BCL2L1/ADIPOQ/MAPT/LRRK2/NF1",8]
["GO:0002028","regulation of sodium ion transport","7/267","88/18866",0.000251374890927847,0.000778607214890036,0.000278885947294248,"DLG1/P2RX7/AKT1/DRD2/NOS3/PRKCE/DMD",7]
["GO:0044282","small molecule catabolic process","17/267","452/18866",0.000258951164713966,0.00080157666795836,0.000287113276241739,"PON1/NOS2/ADA2/TGFB1/CNR1/IDUA/APOE/IDO1/GLUL/CYP27A1/TP53/AKT1/NOS3/PTEN/LEP/ADIPOQ/MTOR",17]
["GO:0045446","endothelial cell differentiation","8/267","117/18866",0.000261439312696475,0.000808276463339627,0.000289513046942356,"TNFRSF1A/VEGFA/IL1B/KDM6B/CTNNB1/DLL1/TNF/GPX1",8]
["GO:1904019","epithelial cell apoptotic process","8/267","117/18866",0.000261439312696475,0.000808276463339627,0.000289513046942356,"CCL2/PPARGC1A/IL6/IL10/PRKCI/BCL2L1/MTOR/TNF",8]
["GO:0010830","regulation of myotube differentiation","6/267","63/18866",0.000262619014021925,0.000810919441565534,0.000290459723870227,"HDAC9/HDAC4/XBP1/BCL2/BDNF/MTOR",6]
["GO:1902686","mitochondrial outer membrane permeabilization involved in programmed cell death","6/267","63/18866",0.000262619014021925,0.000810919441565534,0.000290459723870227,"GCLC/GSK3B/BAX/MAPK8/TP53/BCL2",6]
["GO:0045619","regulation of lymphocyte differentiation","10/267","181/18866",0.000264179724747834,0.000815234465800949,0.000292005303719062,"GLI2/XBP1/SFRP1/IL2/IFNG/IL1A/IL1B/SOD1/IL18/SHH",10]
["GO:0001892","embryonic placenta development","7/267","89/18866",0.000269586715687581,0.000830892883597588,0.000297613924595972,"FGFR2/MAPK1/HIF1A/LIF/IL10/AKT1/MAP2K1",7]
["GO:0055006","cardiac cell development","7/267","89/18866",0.000269586715687581,0.000830892883597588,0.000297613924595972,"IGF1/SRF/VEGFA/PDGFRB/PDLIM5/NEB/MTOR",7]
["GO:0043267","negative regulation of potassium ion transport","5/267","41/18866",0.000270184307644144,0.000832221004359785,0.000298089638421638,"HTR2A/PTK2B/ATF4/NOS3/PTEN",5]
["GO:0006805","xenobiotic metabolic process","8/267","118/18866",0.000277076579915683,0.000852924391811964,0.000305505295137092,"CYP2D6/CYP2E1/GSTM1/CYP1A2/CYP3A4/CYP2C19/NQO1/CYP2B6",8]
["GO:0018027","peptidyl-lysine dimethylation","4/267","23/18866",0.000280964537546439,0.000860647813478141,0.000308271714104876,"SMARCB1/KMT2A/KMT2D/EHMT1",4]
["GO:0033139","regulation of peptidyl-serine phosphorylation of STAT protein","4/267","23/18866",0.000280964537546439,0.000860647813478141,0.000308271714104876,"IFNG/LIF/RET/IFNA1",4]
["GO:0035812","renal sodium excretion","4/267","23/18866",0.000280964537546439,0.000860647813478141,0.000308271714104876,"TAC1/COMT/OXT/DRD2",4]
["GO:0045649","regulation of macrophage differentiation","4/267","23/18866",0.000280964537546439,0.000860647813478141,0.000308271714104876,"TGFB1/LIF/FADD/ADIPOQ",4]
["GO:0048714","positive regulation of oligodendrocyte differentiation","4/267","23/18866",0.000280964537546439,0.000860647813478141,0.000308271714104876,"TNFRSF1B/SHH/HDAC2/MTOR",4]
["GO:1900273","positive regulation of long-term synaptic potentiation","4/267","23/18866",0.000280964537546439,0.000860647813478141,0.000308271714104876,"CREB1/DRD2/SQSTM1/INS",4]
["GO:1901984","negative regulation of protein acetylation","4/267","23/18866",0.000280964537546439,0.000860647813478141,0.000308271714104876,"BRCA1/GSK3B/SIRT1/HDAC2",4]
["GO:2000178","negative regulation of neural precursor cell proliferation","4/267","23/18866",0.000280964537546439,0.000860647813478141,0.000308271714104876,"PAX6/TP53/BDNF/NF1",4]
["GO:0001885","endothelial cell development","6/267","64/18866",0.000286392533510227,0.000874057408200835,0.000313074838781287,"TNFRSF1A/VEGFA/IL1B/CTNNB1/TNF/GPX1",6]
["GO:0002066","columnar/cuboidal epithelial cell development","6/267","64/18866",0.000286392533510227,0.000874057408200835,0.000313074838781287,"PAX6/FGFR1/GSK3B/HIF1A/SOD1/DLL1",6]
["GO:0032835","glomerulus development","6/267","64/18866",0.000286392533510227,0.000874057408200835,0.000313074838781287,"NOTCH3/PDGFRB/IL6R/RET/BCL2/ADIPOQ",6]
["GO:0051898","negative regulation of protein kinase B signaling","6/267","64/18866",0.000286392533510227,0.000874057408200835,0.000313074838781287,"DLG1/SIRT1/TSC2/AKT1/DRD2/PTEN",6]
["GO:1900449","regulation of glutamate receptor signaling pathway","6/267","64/18866",0.000286392533510227,0.000874057408200835,0.000313074838781287,"DLG1/CCL2/PPARGC1A/IFNG/OPRM1/PTK2B",6]
["GO:1901862","negative regulation of muscle tissue development","6/267","64/18866",0.000286392533510227,0.000874057408200835,0.000313074838781287,"TGFB1/FGF8/S100B/SHH/PTEN/DLL1",6]
["GO:0001959","regulation of cytokine-mediated signaling pathway","10/267","183/18866",0.000288509341521742,0.000879979928050128,0.000315196200524348,"VRK2/TNFRSF1A/HIF1A/IFNG/IL6/FADD/PTPN11/ADIPOQ/PRKN/TNF",10]
["GO:0045580","regulation of T cell differentiation","9/267","150/18866",0.000291116011849667,0.0008868470086427,0.000317655890390536,"GLI2/XBP1/IL2/IFNG/IL1A/IL1B/SOD1/IL18/SHH",9]
["GO:0097530","granulocyte migration","9/267","150/18866",0.000291116011849667,0.0008868470086427,0.000317655890390536,"MAPK1/MAPK3/CCL2/IL17A/IL1B/RAC1/CXCL8/CSF1R/DPP4",9]
["GO:1902903","regulation of supramolecular fiber organization","15/267","373/18866",0.000294500996056202,0.00089661187396867,0.000321153525224318,"TAC1/DLG1/HDAC6/SFRP1/STMN1/PTK2B/APOE/RAC1/PIK3R1/MECP2/PRKCE/PRKN/MAPT/MTOR/GPX1",15]
["GO:0000075","cell cycle checkpoint","11/267","219/18866",0.000300200487256566,0.00091340708889216,0.000327169330542292,"BRCA1/DLG1/BAX/EP300/TGFB1/TIMELESS/DUSP1/TP53/PLK2/BCL2L1/PTPN11",11]
["GO:0010907","positive regulation of glucose metabolic process","5/267","42/18866",0.000303184354301919,0.000921363043840219,0.000330019039599551,"IGF1/SIRT1/PPARGC1A/AKT1/INS",5]
["GO:0048246","macrophage chemotaxis","5/267","42/18866",0.000303184354301919,0.000921363043840219,0.000330019039599551,"MAPK1/MAPK3/CCL2/PTK2B/CSF1R",5]
["GO:0061041","regulation of wound healing","9/267","151/18866",0.000305807903775347,0.000928770598266612,0.000332672319448275,"XBP1/APOE/NOS3/PRKCE/PTEN/F2/MTOR/AGER/TNF",9]
["GO:0042475","odontogenesis of dentin-containing tooth","7/267","91/18866",0.000309192438148221,0.000934845944310325,0.000334848421344249,"NGFR/GLI2/BAX/FGF8/SHH/CTNNB1/HDAC2",7]
["GO:0051899","membrane depolarization","7/267","91/18866",0.000309192438148221,0.000934845944310325,0.000334848421344249,"GCLC/P2RX7/TSPO/BCL2/JUN/CCK/LRRK2",7]
["GO:0097306","cellular response to alcohol","7/267","91/18866",0.000309192438148221,0.000934845944310325,0.000334848421344249,"BRCA1/SFRP1/AKT1/CTNNB1/PRKCE/PTEN/PTCH1",7]
["GO:0030111","regulation of Wnt signaling pathway","15/267","375/18866",0.000311677952705427,0.000934845944310325,0.000334848421344249,"FGFR2/GSK3B/ESR1/TSC2/SFRP1/TGFB1/COL1A1/APOE/DVL3/SHH/VCP/CTNNB1/PRKN/LRRK2/TLE1",15]
["GO:0031646","positive regulation of nervous system process","6/267","65/18866",0.000311822778750356,0.000934845944310325,0.000334848421344249,"TNFRSF1B/PTK2B/S100B/PTEN/CCK/MTOR",6]
["GO:0035794","positive regulation of mitochondrial membrane permeability","6/267","65/18866",0.000311822778750356,0.000934845944310325,0.000334848421344249,"GCLC/GSK3B/BAX/MAPK8/TP53/BCL2",6]
["GO:0060828","regulation of canonical Wnt signaling pathway","13/267","295/18866",0.000312435119809141,0.000934845944310325,0.000334848421344249,"FGFR2/GSK3B/SFRP1/TGFB1/COL1A1/APOE/DVL3/SHH/VCP/CTNNB1/PRKN/LRRK2/TLE1",13]
["GO:0001840","neural plate development","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"FGF8/CTNNB1/PTCH1",3]
["GO:0002676","regulation of chronic inflammatory response","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"IDO1/IL10/TNF",3]
["GO:0019614","catechol-containing compound catabolic process","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"COMT/SLC6A3/MAOA",3]
["GO:0030432","peristalsis","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"DLG1/DRD2/GDNF",3]
["GO:0032308","positive regulation of prostaglandin secretion","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"P2RX7/OXT/IL1B",3]
["GO:0035933","glucocorticoid secretion","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"TAC1/POMC/PTPN11",3]
["GO:0042424","catecholamine catabolic process","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"COMT/SLC6A3/MAOA",3]
["GO:0045792","negative regulation of cell size","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"AKT1/PTEN/MTOR",3]
["GO:0051901","positive regulation of mitochondrial depolarization","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"P2RX7/TSPO/CCK",3]
["GO:0060513","prostatic bud formation","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"GLI2/SHH/AR",3]
["GO:0060768","regulation of epithelial cell proliferation involved in prostate gland development","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"SHH/CTNNB1/AR",3]
["GO:0071394","cellular response to testosterone stimulus","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"SIRT1/SRD5A1/AR",3]
["GO:0071600","otic vesicle morphogenesis","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"FGFR2/FGF8/HESX1",3]
["GO:0072203","cell proliferation involved in metanephros development","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"PDGFRB/SHH/PTCH1",3]
["GO:0098779","positive regulation of mitophagy in response to mitochondrial depolarization","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"HDAC6/MFN2/PRKN",3]
["GO:1900222","negative regulation of amyloid-beta clearance","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"IFNG/SRF/TNF",3]
["GO:1903431","positive regulation of cell maturation","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"RET/BCL2/MTOR",3]
["GO:1904338","regulation of dopaminergic neuron differentiation","3/267","10/18866",0.000312489060896041,0.000934845944310325,0.000334848421344249,"GSK3B/SFRP1/SHH",3]
["GO:2001257","regulation of cation channel activity","10/267","185/18866",0.000314685523085043,0.000940853183690791,0.000337000128409385,"PRKACA/DLG1/CCL2/PPARGC1A/IFNG/OPRM1/PTK2B/DRD2/CDK5/DMD",10]
["GO:1903169","regulation of calcium ion transmembrane transport","9/267","152/18866",0.000321107850394627,0.000959480249563359,0.000343672076487745,"PRKACA/BAX/PTK2B/DRD2/CDK5/PRKCE/CHD7/F2/DMD",9]
["GO:0016079","synaptic vesicle exocytosis","8/267","121/18866",0.000328637839215574,0.000981392781820192,0.000351520831545744,"GSK3B/P2RX7/HTR2A/CNR1/DRD2/CDK5/ATP2A2/LRRK2",8]
["GO:1905897","regulation of response to endoplasmic reticulum stress","7/267","92/18866",0.000330674865584947,0.000986885597050592,0.000353488279251785,"BAX/SIRT1/XBP1/PIK3R1/BCL2L1/PRKN/LRRK2",7]
["GO:0021697","cerebellar cortex formation","4/267","24/18866",0.000333427793743069,0.000990365838286223,0.00035473485179215,"CDK5/MAP2K1/PTPN11/DLL1",4]
["GO:0021904","dorsal/ventral neural tube patterning","4/267","24/18866",0.000333427793743069,0.000990365838286223,0.00035473485179215,"PRKACA/GLI2/SHH/PTCH1",4]
["GO:0044062","regulation of excretion","4/267","24/18866",0.000333427793743069,0.000990365838286223,0.00035473485179215,"TAC1/COMT/OXT/DRD2",4]
["GO:0046628","positive regulation of insulin receptor signaling pathway","4/267","24/18866",0.000333427793743069,0.000990365838286223,0.00035473485179215,"SIRT1/LEP/PTPN11/INS",4]
["GO:0062009","secondary palate development","4/267","24/18866",0.000333427793743069,0.000990365838286223,0.00035473485179215,"DLG1/CHD7/FZD2/COL11A2",4]
["GO:0070841","inclusion body assembly","4/267","24/18866",0.000333427793743069,0.000990365838286223,0.00035473485179215,"HDAC6/VCP/PRKN/MAPT",4]
["GO:1903429","regulation of cell maturation","4/267","24/18866",0.000333427793743069,0.000990365838286223,0.00035473485179215,"RET/BCL2/LRRK2/MTOR",4]
["GO:2000209","regulation of anoikis","4/267","24/18866",0.000333427793743069,0.000990365838286223,0.00035473485179215,"PIK3CA/NTRK2/BCL2/TLE1",4]
["GO:0034394","protein localization to cell surface","6/267","66/18866",0.000338989763253731,0.00100259213545155,0.000359114136239618,"TOR1A/AKT1/CTNNB1/BDNF/ERBB4/TNF",6]
["GO:0042490","mechanoreceptor differentiation","6/267","66/18866",0.000338989763253731,0.00100259213545155,0.000359114136239618,"FGFR1/SOD1/NTRK2/BDNF/FZD2/DLL1",6]
["GO:1902108","regulation of mitochondrial membrane permeability involved in apoptotic process","6/267","66/18866",0.000338989763253731,0.00100259213545155,0.000359114136239618,"GCLC/GSK3B/BAX/MAPK8/TP53/BCL2",6]
["GO:0002369","T cell cytokine production","5/267","43/18866",0.000339150433963083,0.00100259213545155,0.000359114136239618,"TNFRSF1B/DLG1/IL1B/IL6/IL18",5]
["GO:0030521","androgen receptor signaling pathway","5/267","43/18866",0.000339150433963083,0.00100259213545155,0.000359114136239618,"HDAC6/SIRT1/EP300/SFRP1/AR",5]
["GO:0045124","regulation of bone resorption","5/267","43/18866",0.000339150433963083,0.00100259213545155,0.000359114136239618,"CD38/P2RX7/IL6/CSF1R/NF1",5]
["GO:0045773","positive regulation of axon extension","5/267","43/18866",0.000339150433963083,0.00100259213545155,0.000359114136239618,"ADNP/SRF/VEGFA/MAPT/L1CAM",5]
["GO:1901031","regulation of response to reactive oxygen species","5/267","43/18866",0.000339150433963083,0.00100259213545155,0.000359114136239618,"HDAC6/IL10/PAWR/LRRK2/TNF",5]
["GO:0010811","positive regulation of cell-substrate adhesion","8/267","122/18866",0.000347468437112187,0.00102657390917228,0.000367704063938714,"GSK3B/OLFM4/SFRP1/VEGFA/PTK2B/RAC1/CDH13/PRKCE",8]
["GO:0002699","positive regulation of immune effector process","11/267","223/18866",0.000350280338758717,0.0010342695040936,0.000370460515765234,"NOS2/P2RX7/XBP1/TGFB1/IL2/IFNG/IL1B/IL6/IL18/FADD/TNF",11]
["GO:0014909","smooth muscle cell migration","7/267","93/18866",0.000353337801748424,0.00104144961282756,0.000373032327826119,"IGF1/HDAC4/PPARGC1A/PDGFRB/ACE/BCL2/ADIPOQ",7]
["GO:0032677","regulation of interleukin-8 production","7/267","93/18866",0.000353337801748424,0.00104144961282756,0.000373032327826119,"IL1B/CRP/IL6/IL10/FADD/ADIPOQ/TNF",7]
["GO:2000117","negative regulation of cysteine-type endopeptidase activity","7/267","93/18866",0.000353337801748424,0.00104144961282756,0.000373032327826119,"NGFR/PTGS2/VEGFA/NGF/AKT1/TNF/GPX1",7]
["GO:0010977","negative regulation of neuron projection development","9/267","154/18866",0.000353609475120486,0.00104163546270005,0.000373098896587304,"CD38/NGFR/APOE/PLK2/CDK5/PTEN/DCC/LRRK2/HDAC2",9]
["GO:0051783","regulation of nuclear division","10/267","188/18866",0.000357650843723226,0.00105291902282433,0.000377140506135651,"IGF1/ATRX/FGF8/PRKAR1A/PDGFRB/IL1A/DUSP1/IL1B/LIF/INS",10]
["GO:0019935","cyclic-nucleotide-mediated signaling","11/267","224/18866",0.000363843131099891,0.00107051782768518,0.000383444145854117,"GNAS/ADNP/PRKAR1A/OPRM1/CNR1/PTK2B/PDE11A/APOE/GNAL/DRD2/MC1R",11]
["GO:0007173","epidermal growth factor receptor signaling pathway","8/267","123/18866",0.000367169210673815,0.00107886174628832,0.000386432817933287,"TGFB1/PTK2B/PIK3CA/CDH13/AKT1/PIK3R1/BRAF/PTPN11",8]
["GO:0071466","cellular response to xenobiotic stimulus","8/267","123/18866",0.000367169210673815,0.00107886174628832,0.000386432817933287,"CYP2D6/CYP2E1/GSTM1/CYP1A2/CYP3A4/CYP2C19/NQO1/CYP2B6",8]
["GO:0043550","regulation of lipid kinase activity","6/267","67/18866",0.000367975476452836,0.00107886174628832,0.000386432817933287,"FGFR3/TGFB1/PDGFRB/PTK2B/PIK3R1/F2",6]
["GO:1900015","regulation of cytokine production involved in inflammatory response","6/267","67/18866",0.000367975476452836,0.00107886174628832,0.000386432817933287,"NOS2/IL17A/IL6/LEP/F2/TNF",6]
["GO:1903672","positive regulation of sprouting angiogenesis","6/267","67/18866",0.000367975476452836,0.00107886174628832,0.000386432817933287,"HDAC9/PTGS2/VEGFA/IL10/PLK2/DLL1",6]
["GO:1905710","positive regulation of membrane permeability","6/267","67/18866",0.000367975476452836,0.00107886174628832,0.000386432817933287,"GCLC/GSK3B/BAX/MAPK8/TP53/BCL2",6]
["GO:0034308","primary alcohol metabolic process","7/267","94/18866",0.000377228178156635,0.00110381012652235,0.000395368970234428,"IGF1/REST/CYP2D6/TTR/CYP1A2/CYP3A4/ADH1C",7]
["GO:0010463","mesenchymal cell proliferation","5/267","44/18866",0.000378253380027988,0.00110381012652235,0.000395368970234428,"FGFR2/FGFR1/VEGFA/SHH/CTNNB1",5]
["GO:0021575","hindbrain morphogenesis","5/267","44/18866",0.000378253380027988,0.00110381012652235,0.000395368970234428,"GLI2/CDK5/MAP2K1/PTPN11/DLL1",5]
["GO:0032620","interleukin-17 production","5/267","44/18866",0.000378253380027988,0.00110381012652235,0.000395368970234428,"TGFB1/IL2/IFNG/IL6/IL18",5]
["GO:0032965","regulation of collagen biosynthetic process","5/267","44/18866",0.000378253380027988,0.00110381012652235,0.000395368970234428,"TGFB1/PDGFRB/IL6/F2/HDAC2",5]
["GO:0033173","calcineurin-NFAT signaling cascade","5/267","44/18866",0.000378253380027988,0.00110381012652235,0.000395368970234428,"IGF1/ERBB3/GSK3B/MTOR/TNF",5]
["GO:0048489","synaptic vesicle transport","5/267","44/18866",0.000378253380027988,0.00110381012652235,0.000395368970234428,"TOR1A/CDK5/CTNNB1/PRKN/LRRK2",5]
["GO:1903053","regulation of extracellular matrix organization","5/267","44/18866",0.000378253380027988,0.00110381012652235,0.000395368970234428,"TNFRSF1B/TNFRSF1A/TGFB1/IL6/DPP4",5]
["GO:0030308","negative regulation of cell growth","10/267","190/18866",0.000388928003634424,0.00113429761807633,0.000406289152837486,"SIRT1/SFRP1/TGFB1/ESR2/TP53/CDKN2A/CDK5/BCL2/DCC/MEG3",10]
["GO:0003309","type B pancreatic cell differentiation","4/267","25/18866",0.00039254889625734,0.00114152395982114,0.000408877524900359,"PAX6/GSK3B/MEN1/DLL1",4]
["GO:0010738","regulation of protein kinase A signaling","4/267","25/18866",0.00039254889625734,0.00114152395982114,0.000408877524900359,"PRKAR1A/ADIPOQ/LRRK2/MC1R",4]
["GO:0045662","negative regulation of myoblast differentiation","4/267","25/18866",0.00039254889625734,0.00114152395982114,0.000408877524900359,"TGFB1/IL18/DLL1/TNF",4]
["GO:0050927","positive regulation of positive chemotaxis","4/267","25/18866",0.00039254889625734,0.00114152395982114,0.000408877524900359,"VEGFA/CDH13/CXCL8/AGER",4]
["GO:0060259","regulation of feeding behavior","4/267","25/18866",0.00039254889625734,0.00114152395982114,0.000408877524900359,"CNR1/CCK/MTOR/INS",4]
["GO:0002637","regulation of immunoglobulin production","6/267","68/18866",0.000398863863735014,0.00115786469280752,0.000414730541300973,"XBP1/TGFB1/IL2/IL6/IL10/TNF",6]
["GO:0010812","negative regulation of cell-substrate adhesion","6/267","68/18866",0.000398863863735014,0.00115786469280752,0.000414730541300973,"COL1A1/MEN1/PIK3R1/CDKN2A/PTEN/NF1",6]
["GO:1904888","cranial skeletal system development","6/267","68/18866",0.000398863863735014,0.00115786469280752,0.000414730541300973,"FGFR2/GNAS/FGF8/CTNNB1/MED12/PAX5",6]
["GO:0070167","regulation of biomineral tissue development","7/267","95/18866",0.000402393991431764,0.00116607846733534,0.000417672597637271,"P2RX7/HIF1A/GATA1/TGFB1/PTK2B/ATF4/NOS3",7]
["GO:0110149","regulation of biomineralization","7/267","95/18866",0.000402393991431764,0.00116607846733534,0.000417672597637271,"P2RX7/HIF1A/GATA1/TGFB1/PTK2B/ATF4/NOS3",7]
["GO:1903725","regulation of phospholipid metabolic process","7/267","95/18866",0.000402393991431764,0.00116607846733534,0.000417672597637271,"FGFR3/HTR2A/TGFB1/GNB3/PDGFRB/PTK2B/PIK3R1",7]
["GO:0003014","renal system process","8/267","125/18866",0.00040930192498534,0.00118540864933399,0.000424596391836667,"TAC1/PRKACA/COMT/OXT/PRKAR1A/DRD2/BCL2/ADIPOQ",8]
["GO:0014047","glutamate secretion","5/267","45/18866",0.000420667881508228,0.00121550621086261,0.000435376907092154,"P2RX7/NTRK2/BDNF/CCK/NF1",5]
["GO:0031057","negative regulation of histone modification","5/267","45/18866",0.000420667881508228,0.00121550621086261,0.000435376907092154,"BRCA1/SIRT1/SMARCB1/DNMT1/PAX5",5]
["GO:0042771","intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","5/267","45/18866",0.000420667881508228,0.00121550621086261,0.000435376907092154,"SIRT1/EP300/BRCA2/TP53/BCL2",5]
["GO:1904646","cellular response to amyloid-beta","5/267","45/18866",0.000420667881508228,0.00121550621086261,0.000435376907092154,"IGF1/NGFR/GSK3B/CDK5/AGER",5]
["GO:0007191","adenylate cyclase-activating dopamine receptor signaling pathway","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"GNAS/OPRM1/GNAL",3]
["GO:0009950","dorsal/ventral axis specification","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"PAX6/SFRP1/CTNNB1",3]
["GO:0014820","tonic smooth muscle contraction","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"CD38/HTR2A/EDNRA",3]
["GO:0032306","regulation of prostaglandin secretion","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"P2RX7/OXT/IL1B",3]
["GO:0033483","gas homeostasis","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"HIF1A/ADNP/SOD2",3]
["GO:0045899","positive regulation of RNA polymerase II transcription preinitiation complex assembly","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"ESR1/CREB1/TP53",3]
["GO:0048742","regulation of skeletal muscle fiber development","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"HDAC9/HDAC4/BCL2",3]
["GO:0051024","positive regulation of immunoglobulin secretion","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"XBP1/IL2/IL6",3]
["GO:0051574","positive regulation of histone H3-K9 methylation","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"BRCA1/SIRT1/MECP2",3]
["GO:0060159","regulation of dopamine receptor signaling pathway","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"DRD2/ALK/LRRK2",3]
["GO:0060174","limb bud formation","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"FGFR2/COL2A1/SHH",3]
["GO:0060525","prostate glandular acinus development","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"FGFR2/ESR1/SFRP1",3]
["GO:0060767","epithelial cell proliferation involved in prostate gland development","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"SHH/CTNNB1/AR",3]
["GO:0090193","positive regulation of glomerulus development","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"IL6R/RET/ADIPOQ",3]
["GO:1901033","positive regulation of response to reactive oxygen species","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"HDAC6/PAWR/TNF",3]
["GO:1901526","positive regulation of mitophagy","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"HDAC6/MFN2/PRKN",3]
["GO:1990440","positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"ATF4/TP53/ATF3",3]
["GO:2000615","regulation of histone H3-K9 acetylation","3/267","11/18866",0.000425183462746327,0.00121588833304262,0.000435513777781401,"BRCA1/SMARCB1/KMT2A",3]
["GO:0060038","cardiac muscle cell proliferation","6/267","69/18866",0.000431740804699168,0.00123338461737416,0.00044178069611534,"FGFR2/FGFR1/MAPK1/PRKAR1A/PTEN/ERBB4",6]
["GO:2000134","negative regulation of G1/S transition of mitotic cell cycle","8/267","126/18866",0.000431795776320856,0.00123338461737416,0.00044178069611534,"BAX/EP300/CCL2/TP53/PLK2/CDKN2A/BCL2/PTEN",8]
["GO:0002440","production of molecular mediator of immune response","13/267","306/18866",0.000442750188098023,0.00126395179483901,0.000452729421069809,"TNFRSF1B/DLG1/SIRT1/XBP1/TGFB1/IL2/IL1B/IL6/IL10/IL18/HLA-DQB1/HLA-DRB1/TNF",13]
["GO:0050777","negative regulation of immune response","9/267","159/18866",0.000446904306384032,0.00127362625672116,0.000456194674685455,"GRN/TGFB1/IL2/IL10/DRD2/HLA-DRB1/TNF/GPX1/INS",9]
["GO:0051092","positive regulation of NF-kappaB transcription factor activity","9/267","159/18866",0.000446904306384032,0.00127362625672116,0.000456194674685455,"IL1B/KRAS/IL18/PRKCI/AR/ALK/AGER/TNF/INS",9]
["GO:0055067","monovalent inorganic cation homeostasis","9/267","159/18866",0.000446904306384032,0.00127362625672116,0.000456194674685455,"TAC1/GRN/COMT/MAPK1/OXT/MAPK3/DRD2/BCL2/LRRK2",9]
["GO:0051495","positive regulation of cytoskeleton organization","11/267","230/18866",0.000454833573149561,0.00129494588014182,0.000463831058294445,"TAC1/DLG1/P2RX7/SFRP1/PTK2B/RAC1/CDK5/MECP2/PRKCE/MAPT/MTOR",11]
["GO:0071621","granulocyte chemotaxis","8/267","127/18866",0.000455283627402434,0.00129494588014182,0.000463831058294445,"MAPK1/MAPK3/CCL2/IL1B/RAC1/CXCL8/CSF1R/DPP4",8]
["GO:0042100","B cell proliferation","7/267","97/18866",0.000456749228359168,0.00129494588014182,0.000463831058294445,"CD38/BAX/IL2/IL10/BCL2/PAWR/IFNA1",7]
["GO:0050764","regulation of phagocytosis","7/267","97/18866",0.000456749228359168,0.00129494588014182,0.000463831058294445,"CCL2/IFNG/IL1B/SOD1/PTEN/ADIPOQ/TNF",7]
["GO:1901655","cellular response to ketone","7/267","97/18866",0.000456749228359168,0.00129494588014182,0.000463831058294445,"SIRT1/SFRP1/NR3C1/AKT1/SRD5A1/AR/PRKCE",7]
["GO:0046578","regulation of Ras protein signal transduction","10/267","194/18866",0.000458343201475841,0.00129494588014182,0.000463831058294445,"IGF1/PDGFRB/MFN2/STMN1/APOE/KRAS/NGF/RAC1/SQSTM1/NF1",10]
["GO:0001783","B cell apoptotic process","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"BAX/IL2/IL10/PTEN",4]
["GO:0030810","positive regulation of nucleotide biosynthetic process","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"NOS2/PPARGC1A/NOS3/VCP",4]
["GO:0032967","positive regulation of collagen biosynthetic process","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"TGFB1/PDGFRB/F2/HDAC2",4]
["GO:0048643","positive regulation of skeletal muscle tissue development","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"SHH/CTNNB1/BCL2/DLL1",4]
["GO:0050926","regulation of positive chemotaxis","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"VEGFA/CDH13/CXCL8/AGER",4]
["GO:0051123","RNA polymerase II preinitiation complex assembly","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"ESR1/TBP/CREB1/TP53",4]
["GO:0060561","apoptotic process involved in morphogenesis","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"TNFRSF1B/TNFRSF1A/BAX/VDR",4]
["GO:0060765","regulation of androgen receptor signaling pathway","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"HDAC6/SIRT1/EP300/SFRP1",4]
["GO:0072202","cell differentiation involved in metanephros development","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"LIF/CTNNB1/GDNF/ADIPOQ",4]
["GO:0072273","metanephric nephron morphogenesis","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"PDGFRB/LIF/CTNNB1/GDNF",4]
["GO:1900373","positive regulation of purine nucleotide biosynthetic process","4/267","26/18866",0.000458794164224091,0.00129494588014182,0.000463831058294445,"NOS2/PPARGC1A/NOS3/VCP",4]
["GO:0032570","response to progesterone","5/267","46/18866",0.00046657234342056,0.0013142716242461,0.000470753262903669,"CD38/TSPO/OXT/TGFB1/FOS",5]
["GO:0061028","establishment of endothelial barrier","5/267","46/18866",0.00046657234342056,0.0013142716242461,0.000470753262903669,"TNFRSF1A/VEGFA/IL1B/CTNNB1/TNF",5]
["GO:0001756","somitogenesis","6/267","70/18866",0.000466694089683222,0.0013142716242461,0.000470753262903669,"EP300/SFRP1/TP53/KDM6A/MED12/DLL1",6]
["GO:0043967","histone H4 acetylation","6/267","70/18866",0.000466694089683222,0.0013142716242461,0.000470753262903669,"BRCA1/SIRT1/SMARCB1/EP300/KMT2A/BRCA2",6]
["GO:0048285","organelle fission","17/267","476/18866",0.000468652462035889,0.00131904269613596,0.000472462192487376,"IGF1/ATRX/FGF8/SMC3/PRKAR1A/PPARGC1A/PDGFRB/IL1A/DUSP1/IL1B/LIF/BRCA2/POGZ/PRKN/MAPT/LRRK2/INS",17]
["GO:0034763","negative regulation of transmembrane transport","8/267","128/18866",0.00047979803006285,0.0013496515854106,0.0004834258580144,"IL1B/AKT1/DRD2/PRKCE/PTEN/LEP/MTOR/TNF",8]
["GO:0048010","vascular endothelial growth factor receptor signaling pathway","7/267","98/18866",0.000486039950057491,0.00136644001725059,0.000489439233729064,"HIF1A/VEGFA/PTK2B/PIK3CA/IL1B/RAC1/PIK3R1",7]
["GO:0007015","actin filament organization","16/267","434/18866",0.000487026699633161,0.00136767396584273,0.000489881216432858,"TAC1/DLG1/SFRP1/SRF/STMN1/PTK2B/RAC1/PIK3R1/PRKCI/INPPL1/PRKCE/BCL2/PAWR/NEB/PRKN/MTOR",16]
["GO:0052548","regulation of endopeptidase activity","16/267","434/18866",0.000487026699633161,0.00136767396584273,0.000489881216432858,"NGFR/PTGS2/REST/BAX/SIRT1/VEGFA/NGF/AKT1/VCP/FADD/MAPT/CCK/SERPINA3/AGER/TNF/GPX1",16]
["GO:0060759","regulation of response to cytokine stimulus","10/267","196/18866",0.000496733625477706,0.00139414895559876,0.000499364178389174,"VRK2/TNFRSF1A/HIF1A/IFNG/IL6/FADD/PTPN11/ADIPOQ/PRKN/TNF",10]
["GO:0015800","acidic amino acid transport","6/267","71/18866",0.000503813394611081,0.00141084704391089,0.00050534519434674,"P2RX7/PER2/NTRK2/BDNF/CCK/NF1",6]
["GO:0033692","cellular polysaccharide biosynthetic process","6/267","71/18866",0.000503813394611081,0.00141084704391089,0.00050534519434674,"IGF1/GSK3B/PER2/AKT1/MTOR/INS",6]
["GO:0035690","cellular response to drug","6/267","71/18866",0.000503813394611081,0.00141084704391089,0.00050534519434674,"NOS2/REST/KMT2A/IL1B/TP53/ADIPOQ",6]
["GO:0051785","positive regulation of nuclear division","6/267","71/18866",0.000503813394611081,0.00141084704391089,0.00050534519434674,"IGF1/FGF8/PDGFRB/IL1A/IL1B/INS",6]
["GO:0010559","regulation of glycoprotein biosynthetic process","5/267","47/18866",0.000516148744148983,0.00144134825477398,0.000516270291009727,"IGF1/GATA1/CTNNB1/BCL2/PAWR",5]
["GO:0042551","neuron maturation","5/267","47/18866",0.000516148744148983,0.00144134825477398,0.000516270291009727,"RET/MECP2/BCL2/LRRK2/MTOR",5]
["GO:0042572","retinol metabolic process","5/267","47/18866",0.000516148744148983,0.00144134825477398,0.000516270291009727,"CYP2D6/TTR/CYP1A2/CYP3A4/ADH1C",5]
["GO:0046677","response to antibiotic","5/267","47/18866",0.000516148744148983,0.00144134825477398,0.000516270291009727,"KDM6B/TP53/SOD1/SRD5A1/EHMT1",5]
["GO:0048483","autonomic nervous system development","5/267","47/18866",0.000516148744148983,0.00144134825477398,0.000516270291009727,"EDNRA/RET/CTNNB1/GDNF/NF1",5]
["GO:0070588","calcium ion transmembrane transport","13/267","312/18866",0.000531518639723264,0.00147993613853994,0.000530091918028264,"PRKACA/BAX/P2RX7/HTR2A/OPRM1/PTK2B/DRD2/CDK5/PRKCE/CHD7/ATP2A2/F2/DMD",13]
["GO:0009651","response to salt stress","4/267","27/18866",0.000532634736822808,0.00147993613853994,0.000530091918028264,"BAX/OXT/TP53/TNF",4]
["GO:0010714","positive regulation of collagen metabolic process","4/267","27/18866",0.000532634736822808,0.00147993613853994,0.000530091918028264,"TGFB1/PDGFRB/F2/HDAC2",4]
["GO:0048668","collateral sprouting","4/267","27/18866",0.000532634736822808,0.00147993613853994,0.000530091918028264,"HDAC6/NGF/BDNF/DCC",4]
["GO:0048799","animal organ maturation","4/267","27/18866",0.000532634736822808,0.00147993613853994,0.000530091918028264,"IGF1/FGFR3/RET/LEP",4]
["GO:0090140","regulation of mitochondrial fission","4/267","27/18866",0.000532634736822808,0.00147993613853994,0.000530091918028264,"PPARGC1A/PRKN/MAPT/LRRK2",4]
["GO:1900078","positive regulation of cellular response to insulin stimulus","4/267","27/18866",0.000532634736822808,0.00147993613853994,0.000530091918028264,"SIRT1/LEP/PTPN11/INS",4]
["GO:1900120","regulation of receptor binding","4/267","27/18866",0.000532634736822808,0.00147993613853994,0.000530091918028264,"IL10/ATP2A2/BDNF/ADIPOQ",4]
["GO:1902473","regulation of protein localization to synapse","4/267","27/18866",0.000532634736822808,0.00147993613853994,0.000530091918028264,"DLG1/ADAM10/GPC6/MAPT",4]
["GO:0055088","lipid homeostasis","9/267","163/18866",0.000535345757876137,0.00148664147334569,0.000532493672871352,"HDAC9/APOB/SIRT1/XBP1/VDR/APOE/IL18/LPL/INS",9]
["GO:0070988","demethylation","6/267","72/18866",0.00054319025420852,0.00150758695901231,0.000539996045698064,"CYP2D6/KDM6B/CYP1A2/FTO/KDM6A/CYP3A4",6]
["GO:0032434","regulation of proteasomal ubiquitin-dependent protein catabolic process","8/267","131/18866",0.000559835671903729,0.00154753350800008,0.00055430432713001,"GCLC/GSK3B/AKT1/PLK2/SHH/VCP/PRKN/LRRK2",8]
["GO:0044106","cellular amine metabolic process","8/267","131/18866",0.000559835671903729,0.00154753350800008,0.00055430432713001,"COMT/IDO1/SLC6A3/MECP2/NQO1/PRKN/MAOA/INS",8]
["GO:0001976","nervous system process involved in regulation of systemic arterial blood pressure","3/267","12/18866",0.000560992519423221,0.00154753350800008,0.00055430432713001,"SOD2/DRD2/MECP2",3]
["GO:0031392","regulation of prostaglandin biosynthetic process","3/267","12/18866",0.000560992519423221,0.00154753350800008,0.00055430432713001,"PTGS2/SIRT1/IL1B",3]
["GO:0036462","TRAIL-activated apoptotic signaling pathway","3/267","12/18866",0.000560992519423221,0.00154753350800008,0.00055430432713001,"ATF3/FADD/PTEN",3]
["GO:0060742","epithelial cell differentiation involved in prostate gland development","3/267","12/18866",0.000560992519423221,0.00154753350800008,0.00055430432713001,"FGFR2/CTNNB1/AR",3]
["GO:0061517","macrophage proliferation","3/267","12/18866",0.000560992519423221,0.00154753350800008,0.00055430432713001,"MAPK1/MAPK3/CSF1R",3]
["GO:0071639","positive regulation of monocyte chemotactic protein-1 production","3/267","12/18866",0.000560992519423221,0.00154753350800008,0.00055430432713001,"IL1B/ADIPOQ/AGER",3]
["GO:0150065","regulation of deacetylase activity","3/267","12/18866",0.000560992519423221,0.00154753350800008,0.00055430432713001,"MAPK8/VEGFA/LRRK2",3]
["GO:1904181","positive regulation of membrane depolarization","3/267","12/18866",0.000560992519423221,0.00154753350800008,0.00055430432713001,"P2RX7/TSPO/CCK",3]
["GO:1905461","positive regulation of vascular associated smooth muscle cell apoptotic process","3/267","12/18866",0.000560992519423221,0.00154753350800008,0.00055430432713001,"SOD2/MFN2/ATF4",3]
["GO:0031952","regulation of protein autophosphorylation","5/267","48/18866",0.000569582490116894,0.00156690103204058,0.000561241496713703,"VEGFA/ACE/JUN/ADIPOQ/INS",5]
["GO:0045601","regulation of endothelial cell differentiation","5/267","48/18866",0.000569582490116894,0.00156690103204058,0.000561241496713703,"TNFRSF1A/VEGFA/IL1B/CTNNB1/TNF",5]
["GO:0048701","embryonic cranial skeleton morphogenesis","5/267","48/18866",0.000569582490116894,0.00156690103204058,0.000561241496713703,"FGFR2/GNAS/FGF8/MED12/PAX5",5]
["GO:0051972","regulation of telomerase activity","5/267","48/18866",0.000569582490116894,0.00156690103204058,0.000561241496713703,"MAPK1/MAPK3/MEN1/TP53/CTNNB1",5]
["GO:0061001","regulation of dendritic spine morphogenesis","5/267","48/18866",0.000569582490116894,0.00156690103204058,0.000561241496713703,"ADAM10/PDLIM5/CDK5/PTEN/LRRK2",5]
["GO:0044264","cellular polysaccharide metabolic process","7/267","101/18866",0.000582994432035983,0.00160291365592272,0.000574140702544131,"IGF1/GSK3B/POMC/PER2/AKT1/MTOR/INS",7]
["GO:1903747","regulation of establishment of protein localization to mitochondrion","6/267","73/18866",0.000584918033638123,0.00160731741439469,0.000575718065724978,"MAPK8/TP53/BCL2/PRKN/MAPT/LRRK2",6]
["GO:0019751","polyol metabolic process","8/267","132/18866",0.000588794609142457,0.00161708002389895,0.000579214892555749,"POU1F1/PTK2B/CYP27A1/CYP3A4/INPPL1/MECP2/PTEN/LEP",8]
["GO:0007093","mitotic cell cycle checkpoint","9/267","166/18866",0.000610695142866542,0.00167630612882498,0.00060042883465771,"BRCA1/DLG1/BAX/EP300/TGFB1/DUSP1/TP53/PLK2/BCL2L1",9]
["GO:0002335","mature B cell differentiation","4/267","28/18866",0.000614545681467852,0.00167857034330907,0.000601239843840769,"XBP1/PTK2B/IL6/DLL1",4]
["GO:0022011","myelination in peripheral nervous system","4/267","28/18866",0.000614545681467852,0.00167857034330907,0.000601239843840769,"SOD1/AKT1/NTRK2/NF1",4]
["GO:0032292","peripheral nervous system axon ensheathment","4/267","28/18866",0.000614545681467852,0.00167857034330907,0.000601239843840769,"SOD1/AKT1/NTRK2/NF1",4]
["GO:0035883","enteroendocrine cell differentiation","4/267","28/18866",0.000614545681467852,0.00167857034330907,0.000601239843840769,"PAX6/GSK3B/MEN1/DLL1",4]
["GO:0051590","positive regulation of neurotransmitter transport","4/267","28/18866",0.000614545681467852,0.00167857034330907,0.000601239843840769,"CNR1/DRD2/CDK5/PRKN",4]
["GO:1902932","positive regulation of alcohol biosynthetic process","4/267","28/18866",0.000614545681467852,0.00167857034330907,0.000601239843840769,"POU1F1/IFNG/IL1B/TNF",4]
["GO:1903579","negative regulation of ATP metabolic process","4/267","28/18866",0.000614545681467852,0.00167857034330907,0.000601239843840769,"HDAC4/TSPO/PPARGC1A/TP53",4]
["GO:2000171","negative regulation of dendrite development","4/267","28/18866",0.000614545681467852,0.00167857034330907,0.000601239843840769,"PLK2/PTEN/DCC/HDAC2",4]
["GO:2000191","regulation of fatty acid transport","4/267","28/18866",0.000614545681467852,0.00167857034330907,0.000601239843840769,"P2RX7/OXT/IL1B/AKT1",4]
["GO:0042770","signal transduction in response to DNA damage","8/267","133/18866",0.000618952465550734,0.00168968270120001,0.000605220131202381,"BRCA1/ATRX/BAX/SIRT1/EP300/BRCA2/TP53/PLK2",8]
["GO:0009150","purine ribonucleotide metabolic process","15/267","401/18866",0.00062667896437158,0.00170436685062846,0.000610479783110619,"IGF1/HDAC4/ACSL4/DLG1/P2RX7/EP300/HIF1A/HTR2A/TGFB1/PPARGC1A/IFNG/LDHA/VCP/LRRK2/INS",15]
["GO:0006692","prostanoid metabolic process","5/267","49/18866",0.000627062268096232,0.00170436685062846,0.000610479783110619,"TNFRSF1A/PTGS2/SIRT1/IL1B/GSTM1",5]
["GO:0006693","prostaglandin metabolic process","5/267","49/18866",0.000627062268096232,0.00170436685062846,0.000610479783110619,"TNFRSF1A/PTGS2/SIRT1/IL1B/GSTM1",5]
["GO:0010712","regulation of collagen metabolic process","5/267","49/18866",0.000627062268096232,0.00170436685062846,0.000610479783110619,"TGFB1/PDGFRB/IL6/F2/HDAC2",5]
["GO:0045058","T cell selection","5/267","49/18866",0.000627062268096232,0.00170436685062846,0.000610479783110619,"SRF/IL6/SHH/BCL2/MTOR",5]
["GO:0048512","circadian behavior","5/267","49/18866",0.000627062268096232,0.00170436685062846,0.000610479783110619,"TP53/SRD5A1/DRD2/PTEN/MTOR",5]
["GO:0060711","labyrinthine layer development","5/267","49/18866",0.000627062268096232,0.00170436685062846,0.000610479783110619,"FGFR2/MAPK1/IL10/AKT1/MAP2K1",5]
["GO:0097720","calcineurin-mediated signaling","5/267","49/18866",0.000627062268096232,0.00170436685062846,0.000610479783110619,"IGF1/ERBB3/GSK3B/MTOR/TNF",5]
["GO:0007179","transforming growth factor beta receptor signaling pathway","10/267","202/18866",0.00062824614287188,0.00170572756463257,0.000610967171368492,"CREBBP/SIRT1/EP300/TGFB1/CREB1/MEN1/TP53/FBN1/FOS/JUN",10]
["GO:1901605","alpha-amino acid metabolic process","10/267","202/18866",0.00062824614287188,0.00170572756463257,0.000610967171368492,"GCLC/NOS2/COMT/MTR/ATF4/IDO1/GLUL/NOS3/MECP2/MTHFR",10]
["GO:0032956","regulation of actin cytoskeleton organization","14/267","360/18866",0.000648782678600359,0.00176052821426717,0.000630595978799777,"TAC1/DLG1/SFRP1/PDGFRB/STMN1/PTK2B/RAC1/PIK3R1/CDK5/PRKCE/CSF1R/NEB/PRKN/MTOR",14]
["GO:1901890","positive regulation of cell junction assembly","7/267","103/18866",0.000655745155410284,0.00177845494892099,0.000637017078271004,"ADNP/OXT/SFRP1/VEGFA/RAC1/NTRK2/BDNF",7]
["GO:0008344","adult locomotory behavior","6/267","75/18866",0.000675808783976156,0.00183187473311235,0.000656151279487679,"DRD2/GDNF/MECP2/CHD7/SNCG/PRKN",6]
["GO:0016311","dephosphorylation","17/267","492/18866",0.00067878325572701,0.00183893911874387,0.000658681641191529,"PON1/DLG1/GSK3B/TGFB1/IFNG/PDGFRB/DUSP1/PPP1R1B/DUSP6/DRD2/INPPL1/BCL2/PTEN/PTPN11/LRRK2/MTOR/TNF",17]
["GO:0003158","endothelium development","8/267","135/18866",0.000683011151999948,0.00184938974074606,0.000662424904240159,"TNFRSF1A/VEGFA/IL1B/KDM6B/CTNNB1/DLL1/TNF/GPX1",8]
["GO:0002711","positive regulation of T cell mediated immunity","5/267","50/18866",0.000688779895466192,0.00186097295349713,0.000666573845065539,"P2RX7/IL1B/IL6/IL18/FADD",5]
["GO:0007622","rhythmic behavior","5/267","50/18866",0.000688779895466192,0.00186097295349713,0.000666573845065539,"TP53/SRD5A1/DRD2/PTEN/MTOR",5]
["GO:0032760","positive regulation of tumor necrosis factor production","5/267","50/18866",0.000688779895466192,0.00186097295349713,0.000666573845065539,"PIK3R1/FADD/LEP/PTPN11/HDAC2",5]
["GO:1903727","positive regulation of phospholipid metabolic process","5/267","50/18866",0.000688779895466192,0.00186097295349713,0.000666573845065539,"FGFR3/HTR2A/TGFB1/PDGFRB/PTK2B",5]
["GO:0032970","regulation of actin filament-based process","15/267","405/18866",0.000693599940016083,0.00187298242320189,0.000670875465023668,"TAC1/DLG1/SFRP1/PDGFRB/STMN1/PTK2B/RAC1/PIK3R1/CDK5/PRKCE/ATP2A2/CSF1R/NEB/PRKN/MTOR",15]
["GO:0032231","regulation of actin filament bundle assembly","7/267","104/18866",0.000694724004359577,0.00187399079079814,0.000671236647847207,"TAC1/SFRP1/STMN1/RAC1/PIK3R1/PRKN/MTOR",7]
["GO:0032649","regulation of interferon-gamma production","7/267","104/18866",0.000694724004359577,0.00187399079079814,0.000671236647847207,"IL2/IL1B/IL10/IL18/FADD/HLA-DRB1/TNF",7]
["GO:0010882","regulation of cardiac muscle contraction by calcium ion signaling","4/267","29/18866",0.000705005140667104,0.0018976230012673,0.000679701366998672,"HDAC4/PRKACA/ATP2A2/DMD",4]
["GO:0031063","regulation of histone deacetylation","4/267","29/18866",0.000705005140667104,0.0018976230012673,0.000679701366998672,"MAPK8/VEGFA/TP53/LRRK2",4]
["GO:0036296","response to increased oxygen levels","4/267","29/18866",0.000705005140667104,0.0018976230012673,0.000679701366998672,"COL1A1/PDGFRB/POLG/HDAC2",4]
["GO:0051569","regulation of histone H3-K4 methylation","4/267","29/18866",0.000705005140667104,0.0018976230012673,0.000679701366998672,"BRCA1/KMT2A/DNMT1/CTNNB1",4]
["GO:0016054","organic acid catabolic process","12/267","282/18866",0.000719369522974021,0.00192795896461647,0.000690567274370095,"PON1/NOS2/TGFB1/CNR1/IDUA/IDO1/GLUL/AKT1/NOS3/LEP/ADIPOQ/MTOR",12]
["GO:0046395","carboxylic acid catabolic process","12/267","282/18866",0.000719369522974021,0.00192795896461647,0.000690567274370095,"PON1/NOS2/TGFB1/CNR1/IDUA/IDO1/GLUL/AKT1/NOS3/LEP/ADIPOQ/MTOR",12]
["GO:0003337","mesenchymal to epithelial transition involved in metanephros morphogenesis","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"LIF/CTNNB1/GDNF",3]
["GO:0019336","phenol-containing compound catabolic process","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"COMT/SLC6A3/MAOA",3]
["GO:0034370","triglyceride-rich lipoprotein particle remodeling","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"APOB/APOE/LPL",3]
["GO:0043970","histone H3-K9 acetylation","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"BRCA1/SMARCB1/KMT2A",3]
["GO:0060123","regulation of growth hormone secretion","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"DRD2/CHD7/PTPN11",3]
["GO:0061000","negative regulation of dendritic spine development","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"PLK2/PTEN/HDAC2",3]
["GO:0061029","eyelid development in camera-type eye","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"SRF/JUN/HDAC2",3]
["GO:0071287","cellular response to manganese ion","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"ATF4/PRKN/LRRK2",3]
["GO:0071872","cellular response to epinephrine stimulus","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"PRKACA/SRD5A1/ADIPOQ",3]
["GO:0090042","tubulin deacetylation","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"HDAC6/EP300/MAPT",3]
["GO:0090179","planar cell polarity pathway involved in neural tube closure","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"SFRP1/DVL3/FZD2",3]
["GO:1900103","positive regulation of endoplasmic reticulum unfolded protein response","3/267","13/18866",0.000721681414954574,0.00192795896461647,0.000690567274370095,"BAX/XBP1/PIK3R1",3]
["GO:1901616","organic hydroxy compound catabolic process","6/267","76/18866",0.000725167360989627,0.00193623563284556,0.000693531858328948,"COMT/APOE/CYP27A1/SLC6A3/PTEN/MAOA",6]
["GO:1902806","regulation of cell cycle G1/S phase transition","10/267","206/18866",0.000730973045313344,0.00195069396859943,0.000698710627014752,"BAX/EP300/CCL2/MEN1/TP53/AKT1/PLK2/CDKN2A/BCL2/PTEN",10]
["GO:0021879","forebrain neuron differentiation","5/267","51/18866",0.000754930168720118,0.00201032871062376,0.000720070937069744,"PAX6/FGFR2/FGF8/ERBB4/CSF1R",5]
["GO:0035176","social behavior","5/267","51/18866",0.000754930168720118,0.00201032871062376,0.000720070937069744,"OXT/GRPR/MECP2/PTEN/MTOR",5]
["GO:0048146","positive regulation of fibroblast proliferation","5/267","51/18866",0.000754930168720118,0.00201032871062376,0.000720070937069744,"IGF1/NGFR/ESR1/PDGFRB/JUN",5]
["GO:0071827","plasma lipoprotein particle organization","5/267","51/18866",0.000754930168720118,0.00201032871062376,0.000720070937069744,"PRKACA/APOB/APOE/ALB/LPL",5]
["GO:0006342","chromatin silencing","6/267","77/18866",0.000777268003063754,0.00206673237260132,0.000740273920551857,"SIRT1/KMT2D/MECP2/MTHFR/HDAC2/HOTAIR",6]
["GO:0060411","cardiac septum morphogenesis","6/267","77/18866",0.000777268003063754,0.00206673237260132,0.000740273920551857,"FGFR2/FGF8/TP53/NOS3/CHD7/FZD2",6]
["GO:0014812","muscle cell migration","7/267","106/18866",0.000778180825253453,0.00206673237260132,0.000740273920551857,"IGF1/HDAC4/PPARGC1A/PDGFRB/ACE/BCL2/ADIPOQ",7]
["GO:0046632","alpha-beta T cell differentiation","7/267","106/18866",0.000778180825253453,0.00206673237260132,0.000740273920551857,"IL2/IFNG/IL6/IL18/SHH/BCL2/MTOR",7]
["GO:0071156","regulation of cell cycle arrest","7/267","106/18866",0.000778180825253453,0.00206673237260132,0.000740273920551857,"BRCA1/PRKACA/BAX/EP300/TP53/PLK2/CDK5",7]
["GO:0001844","protein insertion into mitochondrial membrane involved in apoptotic signaling pathway","4/267","30/18866",0.000804493516367628,0.00212756150806333,0.000762062045221119,"BAX/MAPK8/TP53/BCL2",4]
["GO:0010758","regulation of macrophage chemotaxis","4/267","30/18866",0.000804493516367628,0.00212756150806333,0.000762062045221119,"MAPK1/MAPK3/PTK2B/CSF1R",4]
["GO:0019934","cGMP-mediated signaling","4/267","30/18866",0.000804493516367628,0.00212756150806333,0.000762062045221119,"ADNP/PTK2B/PDE11A/APOE",4]
["GO:0033688","regulation of osteoblast proliferation","4/267","30/18866",0.000804493516367628,0.00212756150806333,0.000762062045221119,"FGFR2/GATA1/SFRP1/BCL2",4]
["GO:0044030","regulation of DNA methylation","4/267","30/18866",0.000804493516367628,0.00212756150806333,0.000762062045221119,"BRCA1/KMT2A/PIK3CA/MECP2",4]
["GO:0044788","modulation by host of viral process","4/267","30/18866",0.000804493516367628,0.00212756150806333,0.000762062045221119,"APOE/CRP/CSF1R/PRKN",4]
["GO:0048265","response to pain","4/267","30/18866",0.000804493516367628,0.00212756150806333,0.000762062045221119,"TAC1/COMT/TSPO/RET",4]
["GO:1903205","regulation of hydrogen peroxide-induced cell death","4/267","30/18866",0.000804493516367628,0.00212756150806333,0.000762062045221119,"HDAC6/IL10/PAWR/LRRK2",4]
["GO:0006937","regulation of muscle contraction","9/267","173/18866",0.000820649734903328,0.00216799160125519,0.000776543525258009,"HDAC4/PRKACA/PTGS2/DLG1/OXT/SRF/SOD1/ATP2A2/DMD",9]
["GO:0050954","sensory perception of mechanical stimulus","9/267","173/18866",0.000820649734903328,0.00216799160125519,0.000776543525258009,"COL11A1/FGFR1/HTR2A/COL1A1/COL2A1/SOD1/CHD7/COL11A2/GPX1",9]
["GO:0043266","regulation of potassium ion transport","7/267","107/18866",0.000822778673209923,0.00217131813707037,0.000777735042719295,"DLG1/HTR2A/PTK2B/ATF4/DRD2/NOS3/PTEN",7]
["GO:0099175","regulation of postsynapse organization","7/267","107/18866",0.000822778673209923,0.00217131813707037,0.000777735042719295,"APOE/ADAM10/PDLIM5/CDK5/PTEN/LRRK2/INS",7]
["GO:0000186","activation of MAPKK activity","5/267","52/18866",0.000825710710505686,0.00217675479279561,0.000779682374895326,"MAPK1/MAPK3/NGF/BRAF/LRRK2",5]
["GO:0009948","anterior/posterior axis specification","5/267","52/18866",0.000825710710505686,0.00217675479279561,0.000779682374895326,"SRF/KDM6A/SHH/OTX2/CTNNB1",5]
["GO:0043900","regulation of multi-organism process","6/267","78/18866",0.000832212750299805,0.00219158136194458,0.000784993039506645,"IGF1/HDAC4/OXT/VEGFA/CNR1/HDAC2",6]
["GO:0061045","negative regulation of wound healing","6/267","78/18866",0.000832212750299805,0.00219158136194458,0.000784993039506645,"APOE/NOS3/PTEN/F2/AGER/TNF",6]
["GO:0009308","amine metabolic process","8/267","140/18866",0.00086676460939599,0.00228136831561106,0.000817153439704679,"COMT/IDO1/SLC6A3/MECP2/NQO1/PRKN/MAOA/INS",8]
["GO:0001909","leukocyte mediated cytotoxicity","7/267","108/18866",0.000869371051078498,0.00228702300212589,0.000819178867385263,"NOS2/P2RX7/IL18/FADD/LEP/F2/AGER",7]
["GO:0045599","negative regulation of fat cell differentiation","5/267","53/18866",0.000901321815470407,0.0023673328903965,0.000847944718560437,"SIRT1/TGFB1/IL6/ADIPOQ/TNF",5]
["GO:0048168","regulation of neuronal synaptic plasticity","5/267","53/18866",0.000901321815470407,0.0023673328903965,0.000847944718560437,"APOE/KRAS/DRD2/S100B/NF1",5]
["GO:0051703","intraspecies interaction between organisms","5/267","53/18866",0.000901321815470407,0.0023673328903965,0.000847944718560437,"OXT/GRPR/MECP2/PTEN/MTOR",5]
["GO:0007586","digestion","8/267","141/18866",0.000907877466123596,0.00236985566620625,0.000848848340705286,"TAC1/OXT/PPARGC1A/VDR/SST/LEP/CCK/SERPINA3",8]
["GO:0014854","response to inactivity","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"HDAC4/IL10/DRD2",3]
["GO:0035815","positive regulation of renal sodium excretion","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"TAC1/OXT/DRD2",3]
["GO:0045898","regulation of RNA polymerase II transcription preinitiation complex assembly","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"ESR1/CREB1/TP53",3]
["GO:0050930","induction of positive chemotaxis","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"VEGFA/CXCL8/AGER",3]
["GO:0051709","regulation of killing of cells of other organism","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"NOS2/P2RX7/IFNG",3]
["GO:0060831","smoothened signaling pathway involved in dorsal/ventral neural tube patterning","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"PRKACA/GLI2/PTCH1",3]
["GO:0090178","regulation of establishment of planar polarity involved in neural tube closure","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"SFRP1/DVL3/FZD2",3]
["GO:0090239","regulation of histone H4 acetylation","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"BRCA1/SIRT1/SMARCB1",3]
["GO:0099550","trans-synaptic signaling, modulating synaptic transmission","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"CNR1/NTRK2/BDNF",3]
["GO:1900452","regulation of long-term synaptic depression","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"SORCS3/MAPT/AGER",3]
["GO:1902430","negative regulation of amyloid-beta formation","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"IGF1/APOE/NTRK2",3]
["GO:1904925","positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"HDAC6/MFN2/PRKN",3]
["GO:2001279","regulation of unsaturated fatty acid biosynthetic process","3/267","14/18866",0.000908927218262561,0.00236985566620625,0.000848848340705286,"PTGS2/SIRT1/IL1B",3]
["GO:0009259","ribonucleotide metabolic process","15/267","416/18866",0.000909808357822965,0.0023709149950992,0.00084922777713505,"IGF1/HDAC4/ACSL4/DLG1/P2RX7/EP300/HIF1A/HTR2A/TGFB1/PPARGC1A/IFNG/LDHA/VCP/LRRK2/INS",15]
["GO:0034368","protein-lipid complex remodeling","4/267","31/18866",0.000913492690637102,0.0023718507562928,0.000849562953385574,"APOB/APOE/ALB/LPL",4]
["GO:0034369","plasma lipoprotein particle remodeling","4/267","31/18866",0.000913492690637102,0.0023718507562928,0.000849562953385574,"APOB/APOE/ALB/LPL",4]
["GO:0048710","regulation of astrocyte differentiation","4/267","31/18866",0.000913492690637102,0.0023718507562928,0.000849562953385574,"LIF/IL6/F2/NF1",4]
["GO:0061037","negative regulation of cartilage development","4/267","31/18866",0.000913492690637102,0.0023718507562928,0.000849562953385574,"GLI2/CTNNB1/LEP/PTPN11",4]
["GO:0070229","negative regulation of lymphocyte apoptotic process","4/267","31/18866",0.000913492690637102,0.0023718507562928,0.000849562953385574,"HIF1A/IL2/IDO1/FADD",4]
["GO:1900745","positive regulation of p38MAPK cascade","4/267","31/18866",0.000913492690637102,0.0023718507562928,0.000849562953385574,"VEGFA/IL1B/LEP/AGER",4]
["GO:1902253","regulation of intrinsic apoptotic signaling pathway by p53 class mediator","4/267","31/18866",0.000913492690637102,0.0023718507562928,0.000849562953385574,"SIRT1/TP53/BCL2/PRKN",4]
["GO:0002286","T cell activation involved in immune response","7/267","109/18866",0.000918020363072854,0.00238236781331744,0.000853330012507265,"IL2/IFNG/IL6/TP53/IL18/IFNA1/MTOR",7]
["GO:0007254","JNK cascade","10/267","213/18866",0.000943935679092117,0.00244834849127633,0.000876963345879703,"SFRP1/MAPK8/PTK2B/IL1B/MEN1/AKT1/DVL3/PRKN/AGER/TNF",10]
["GO:0007006","mitochondrial membrane organization","8/267","142/18866",0.000950539639265417,0.00246296514790298,0.000882198822833476,"GCLC/GSK3B/BAX/MAPK8/MFN2/TP53/BCL2L1/BCL2",8]
["GO:0035050","embryonic heart tube development","6/267","80/18866",0.000951050832196465,0.00246296514790298,0.000882198822833476,"HIF1A/FGF8/SRF/SHH/CTNNB1/DLL1",6]
["GO:1901224","positive regulation of NIK/NF-kappaB signaling","6/267","80/18866",0.000951050832196465,0.00246296514790298,0.000882198822833476,"EP300/IL1B/IL18/NR3C2/AGER/TNF",6]
["GO:0022412","cellular process involved in reproduction in multicellular organism","14/267","375/18866",0.000962696582800551,0.00249183205698452,0.000892538536017099,"IGF1/PRKACA/BAX/SFRP1/PRKAR1A/PTK2B/PRMT7/BRCA2/AKT1/KMT2D/CTNNB1/BCL2L1/BCL2/MTOR",14]
["GO:1901800","positive regulation of proteasomal protein catabolic process","7/267","110/18866",0.000968789980894032,0.00250630485730772,0.000897722485704368,"GCLC/GSK3B/AKT1/PLK2/VCP/PRKN/LRRK2",7]
["GO:0006584","catecholamine metabolic process","5/267","54/18866",0.000981966295171955,0.00253382827482872,0.000907580979462614,"COMT/SLC6A3/DRD2/PRKN/MAOA",5]
["GO:0009712","catechol-containing compound metabolic process","5/267","54/18866",0.000981966295171955,0.00253382827482872,0.000907580979462614,"COMT/SLC6A3/DRD2/PRKN/MAOA",5]
["GO:0030857","negative regulation of epithelial cell differentiation","5/267","54/18866",0.000981966295171955,0.00253382827482872,0.000907580979462614,"GSK3B/IFNG/VEGFA/CTNNB1/DLL1",5]
["GO:0032757","positive regulation of interleukin-8 production","5/267","54/18866",0.000981966295171955,0.00253382827482872,0.000907580979462614,"IL1B/IL6/FADD/ADIPOQ/TNF",5]
["GO:1903018","regulation of glycoprotein metabolic process","5/267","54/18866",0.000981966295171955,0.00253382827482872,0.000907580979462614,"IGF1/GATA1/CTNNB1/BCL2/PAWR",5]
["GO:0097549","chromatin organization involved in negative regulation of transcription","8/267","143/18866",0.00099479320088293,0.00256560044008702,0.000918961313777782,"SIRT1/DNMT1/CDKN2A/KMT2D/MECP2/MTHFR/HDAC2/HOTAIR",8]
["GO:0051604","protein maturation","12/267","293/18866",0.00100249342167616,0.002584124757062,0.00092559645867337,"CREBBP/PRKACA/P2RX7/EP300/NGF/ADAM10/ACE/SHH/FADD/PTCH1/LRRK2/HP",12]
["GO:0001937","negative regulation of endothelial cell proliferation","6/267","81/18866",0.00101515624343626,0.00261406659281961,0.000936321195189165,"NGFR/CCL2/APOE/PRL/NF1/TNF",6]
["GO:0071158","positive regulation of cell cycle arrest","6/267","81/18866",0.00101515624343626,0.00261406659281961,0.000936321195189165,"BRCA1/PRKACA/BAX/EP300/TP53/PLK2",6]
["GO:0002724","regulation of T cell cytokine production","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"TNFRSF1B/IL1B/IL6/IL18",4]
["GO:0003176","aortic valve development","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"TNFRSF1B/TNFRSF1A/TGFB1/NOS3",4]
["GO:0008210","estrogen metabolic process","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"COMT/CYP2D6/CYP1A2/CYP3A4",4]
["GO:0032350","regulation of hormone metabolic process","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"REST/HIF1A/PPARGC1A/GNB3",4]
["GO:0034367","protein-containing complex remodeling","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"APOB/APOE/ALB/LPL",4]
["GO:0038128","ERBB2 signaling pathway","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"ERBB3/PIK3CA/PIK3R1/ERBB4",4]
["GO:0046320","regulation of fatty acid oxidation","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"PPARGC1A/CNR1/AKT1/MTOR",4]
["GO:0048741","skeletal muscle fiber development","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"HDAC9/HDAC4/BCL2/GPX1",4]
["GO:0051968","positive regulation of synaptic transmission, glutamatergic","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"PTGS2/CCL2/PTK2B/GLUL",4]
["GO:1901889","negative regulation of cell junction assembly","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"IL1B/ACE/PTEN/TNF",4]
["GO:1903959","regulation of anion transmembrane transport","4/267","32/18866",0.00103248528155923,0.0026436918004232,0.00094693252003732,"ABCB1/PER2/AKT1/MTOR",4]
["GO:0022029","telencephalon cell migration","5/267","55/18866",0.00106784932230042,0.00272585463509509,0.000976362070061573,"SRF/DRD2/CDK5/CTNNB1/LRRK2",5]
["GO:0030199","collagen fibril organization","5/267","55/18866",0.00106784932230042,0.00272585463509509,0.000976362070061573,"COL11A1/COL1A1/COL2A1/NF1/COL11A2",5]
["GO:0032655","regulation of interleukin-12 production","5/267","55/18866",0.00106784932230042,0.00272585463509509,0.000976362070061573,"IFNG/IL17A/IDO1/IL10/AGER",5]
["GO:0042304","regulation of fatty acid biosynthetic process","5/267","55/18866",0.00106784932230042,0.00272585463509509,0.000976362070061573,"BRCA1/PTGS2/SIRT1/IL1B/ADIPOQ",5]
["GO:0060350","endochondral bone morphogenesis","5/267","55/18866",0.00106784932230042,0.00272585463509509,0.000976362070061573,"FGFR3/GNAS/COL1A1/COL2A1/INPPL1",5]
["GO:0071825","protein-lipid complex subunit organization","5/267","55/18866",0.00106784932230042,0.00272585463509509,0.000976362070061573,"PRKACA/APOB/APOE/ALB/LPL",5]
["GO:0010256","endomembrane system organization","16/267","468/18866",0.00108487542278492,0.00276790137249112,0.000991422608886633,"P2RX7/MAPK1/MAPK3/CREB1/MAP2K2/SYNE1/TOR1A/SOD1/AKT1/SQSTM1/MAP2K1/AR/PTEN/ATP2A2/PRKN/LRRK2",16]
["GO:0002281","macrophage activation involved in immune response","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"GRN/IFNG/PRKCE",3]
["GO:0010763","positive regulation of fibroblast migration","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"TGFB1/AKT1/PRKCE",3]
["GO:0021924","cell proliferation in external granule layer","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"GLI2/RERE/SHH",3]
["GO:0021930","cerebellar granule cell precursor proliferation","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"GLI2/RERE/SHH",3]
["GO:0044849","estrous cycle","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"ADNP/OPRM1/GNRH1",3]
["GO:0045651","positive regulation of macrophage differentiation","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"TGFB1/LIF/FADD",3]
["GO:0045779","negative regulation of bone resorption","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"CD38/P2RX7/IL6",3]
["GO:0048484","enteric nervous system development","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"EDNRA/RET/GDNF",3]
["GO:0060134","prepulse inhibition","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"SLC6A3/DRD2/PTEN",3]
["GO:0090177","establishment of planar polarity involved in neural tube closure","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"SFRP1/DVL3/FZD2",3]
["GO:0090192","regulation of glomerulus development","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"IL6R/RET/ADIPOQ",3]
["GO:1900119","positive regulation of execution phase of apoptosis","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"BAX/IL6/TP53",3]
["GO:1902043","positive regulation of extrinsic apoptotic signaling pathway via death domain receptors","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"SFRP1/ATF3/PTEN",3]
["GO:1904923","regulation of autophagy of mitochondrion in response to mitochondrial depolarization","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"HDAC6/MFN2/PRKN",3]
["GO:2000846","regulation of corticosteroid hormone secretion","3/267","15/18866",0.00112432147301204,0.00284672267482205,0.00101965526990896,"TAC1/POMC/PTPN11",3]
["GO:0048813","dendrite morphogenesis","8/267","146/18866",0.00113753216580494,0.00287871165933303,0.00103111326577352,"GSK3B/HDAC6/ADAM10/RERE/PDLIM5/CDK5/PTEN/LRRK2",8]
["GO:0001570","vasculogenesis","6/267","83/18866",0.00115328140078222,0.00291413665693604,0.00104380199229117,"TGFB1/VEGFA/PDGFRB/NTRK2/SHH/CTNNB1",6]
["GO:0048041","focal adhesion assembly","6/267","83/18866",0.00115328140078222,0.00291413665693604,0.00104380199229117,"SFRP1/VEGFA/PTK2B/RAC1/BCL2/PTEN",6]
["GO:0048644","muscle organ morphogenesis","6/267","83/18866",0.00115328140078222,0.00291413665693604,0.00104380199229117,"COL11A1/FGFR2/TGFB1/LIF/CHD7/FZD2",6]
["GO:0001755","neural crest cell migration","5/267","56/18866",0.00115917827444808,0.00292459682886268,0.00104754867598589,"HIF1A/SHH/RET/GDNF/ERBB4",5]
["GO:0031529","ruffle organization","5/267","56/18866",0.00115917827444808,0.00292459682886268,0.00104754867598589,"PDGFRB/RAC1/INPPL1/CSF1R/MTOR",5]
["GO:1904645","response to amyloid-beta","5/267","56/18866",0.00115917827444808,0.00292459682886268,0.00104754867598589,"IGF1/NGFR/GSK3B/CDK5/AGER",5]
["GO:0003338","metanephros morphogenesis","4/267","33/18866",0.00116195393325019,0.00292568632814835,0.001047938919018,"PDGFRB/LIF/CTNNB1/GDNF",4]
["GO:0010039","response to iron ion","4/267","33/18866",0.00116195393325019,0.00292568632814835,0.001047938919018,"HIF1A/SLC6A3/DRD2/BCL2",4]
["GO:0043552","positive regulation of phosphatidylinositol 3-kinase activity","4/267","33/18866",0.00116195393325019,0.00292568632814835,0.001047938919018,"FGFR3/TGFB1/PDGFRB/PTK2B",4]
["GO:0045879","negative regulation of smoothened signaling pathway","4/267","33/18866",0.00116195393325019,0.00292568632814835,0.001047938919018,"PRKACA/GLI2/VCP/PTCH1",4]
["GO:0006520","cellular amino acid metabolic process","13/267","340/18866",0.00117110693219365,0.00294724642764259,0.00105566143771064,"GCLC/NOS2/FOLH1/COMT/MTR/ATF4/IDO1/GLUL/NOS3/MECP2/MTHFR/NQO1/INS",13]
["GO:0071346","cellular response to interferon-gamma","9/267","182/18866",0.00117331500380014,0.00295131577530181,0.00105711901973031,"NOS2/CCL2/IFNG/FLNB/TP53/NCAM1/HLA-DQB1/HLA-DRB1/HLA-DQA1",9]
["GO:0019693","ribose phosphate metabolic process","15/267","427/18866",0.00118060908280579,0.00296816774947096,0.00106315515539675,"IGF1/HDAC4/ACSL4/DLG1/P2RX7/EP300/HIF1A/HTR2A/TGFB1/PPARGC1A/IFNG/LDHA/VCP/LRRK2/INS",15]
["GO:0007043","cell-cell junction assembly","8/267","147/18866",0.00118858427846606,0.00298521192272688,0.00106926013402194,"PRKACA/DLG1/SRF/IL1B/ACE/PRKCI/CTNNB1/TNF",8]
["GO:0051592","response to calcium ion","8/267","147/18866",0.00118858427846606,0.00298521192272688,0.00106926013402194,"P2RX7/FUS/DUSP1/PTK2B/BRAF/FOS/JUN/PENK",8]
["GO:0032411","positive regulation of transporter activity","7/267","114/18866",0.00119437214882553,0.00299824039169728,0.00107392674491523,"PON1/ABCB1/CCL2/IFNG/KMT2A/CDK5/DMD",7]
["GO:1903670","regulation of sprouting angiogenesis","8/267","148/18866",0.00124144731066386,0.0031148474483139,0.00111569372167041,"HDAC9/NGFR/PTGS2/VEGFA/GLUL/IL10/PLK2/DLL1",8]
["GO:0030520","intracellular estrogen receptor signaling pathway","5/267","57/18866",0.00125616257765049,0.00314528190926559,0.00112659490947162,"BRCA1/ESR1/ESR2/KMT2D/AR",5]
["GO:0045747","positive regulation of Notch signaling pathway","5/267","57/18866",0.00125616257765049,0.00314528190926559,0.00112659490947162,"CREBBP/EP300/PRKCI/NOS3/DLL1",5]
["GO:0048016","inositol phosphate-mediated signaling","5/267","57/18866",0.00125616257765049,0.00314528190926559,0.00112659490947162,"IGF1/ERBB3/GSK3B/MTOR/TNF",5]
["GO:1905517","macrophage migration","5/267","57/18866",0.00125616257765049,0.00314528190926559,0.00112659490947162,"MAPK1/MAPK3/CCL2/PTK2B/CSF1R",5]
["GO:0032609","interferon-gamma production","7/267","115/18866",0.00125672689945621,0.00314528190926559,0.00112659490947162,"IL2/IL1B/IL10/IL18/FADD/HLA-DRB1/TNF",7]
["GO:0046328","regulation of JNK cascade","9/267","184/18866",0.00126627788823615,0.00316759794386929,0.00113458819328827,"SFRP1/PTK2B/IL1B/MEN1/AKT1/DVL3/PRKN/AGER/TNF",9]
["GO:0017157","regulation of exocytosis","10/267","222/18866",0.0012900177768128,0.00322536743095959,0.00115528039575413,"GSK3B/REST/HTR2A/IFNG/CNR1/DRD2/CDK5/ATP2A2/PRKN/LRRK2",10]
["GO:0007202","activation of phospholipase C activity","4/267","34/18866",0.00130238063893123,0.00324490345817547,0.00116227792076067,"HTR2A/NTRK2/EDNRA/BDNF",4]
["GO:0035633","maintenance of blood-brain barrier","4/267","34/18866",0.00130238063893123,0.00324490345817547,0.00116227792076067,"PTGS2/VEGFA/IL6/DMD",4]
["GO:0036474","cell death in response to hydrogen peroxide","4/267","34/18866",0.00130238063893123,0.00324490345817547,0.00116227792076067,"HDAC6/IL10/PAWR/LRRK2",4]
["GO:0045907","positive regulation of vasoconstriction","4/267","34/18866",0.00130238063893123,0.00324490345817547,0.00116227792076067,"CD38/PTGS2/HTR2A/AKT1",4]
["GO:0048854","brain morphogenesis","4/267","34/18866",0.00130238063893123,0.00324490345817547,0.00116227792076067,"FGF8/HESX1/PTEN/NF1",4]
["GO:0055094","response to lipoprotein particle","4/267","34/18866",0.00130238063893123,0.00324490345817547,0.00116227792076067,"APOE/CDH13/AKT1/LPL",4]
["GO:0070232","regulation of T cell apoptotic process","4/267","34/18866",0.00130238063893123,0.00324490345817547,0.00116227792076067,"HIF1A/IDO1/TP53/FADD",4]
["GO:2000045","regulation of G1/S transition of mitotic cell cycle","9/267","185/18866",0.00131493886145411,0.00327455847144158,0.00117289992157004,"BAX/EP300/CCL2/TP53/AKT1/PLK2/CDKN2A/BCL2/PTEN",9]
["GO:0016485","protein processing","10/267","223/18866",0.00133413690535994,0.00332071065227427,0.00118943097140501,"PRKACA/P2RX7/NGF/ADAM10/ACE/SHH/FADD/PTCH1/LRRK2/HP",10]
["GO:0060041","retina development in camera-type eye","8/267","150/18866",0.00135278956119727,0.00336546002942598,0.00120545955706299,"PAX6/BAX/HIF1A/PDGFRB/NTRK2/RET/CHD7/DLL1",8]
["GO:0007566","embryo implantation","5/267","58/18866",0.00135901354991208,0.00336645889739089,0.00120581733725471,"PTGS2/VEGFA/IL1B/LIF/SOD1",5]
["GO:0021885","forebrain cell migration","5/267","58/18866",0.00135901354991208,0.00336645889739089,0.00120581733725471,"SRF/DRD2/CDK5/CTNNB1/LRRK2",5]
["GO:0043551","regulation of phosphatidylinositol 3-kinase activity","5/267","58/18866",0.00135901354991208,0.00336645889739089,0.00120581733725471,"FGFR3/TGFB1/PDGFRB/PTK2B/PIK3R1",5]
["GO:0051055","negative regulation of lipid biosynthetic process","5/267","58/18866",0.00135901354991208,0.00336645889739089,0.00120581733725471,"BRCA1/REST/SIRT1/APOE/SOD1",5]
["GO:0002830","positive regulation of type 2 immune response","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"IDO1/IL6/IL18",3]
["GO:0017014","protein nitrosylation","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"NOS2/ACE/DMD",3]
["GO:0018119","peptidyl-cysteine S-nitrosylation","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"NOS2/ACE/DMD",3]
["GO:0019372","lipoxygenase pathway","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"PON1/PTGS2/GPX1",3]
["GO:0021534","cell proliferation in hindbrain","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"GLI2/RERE/SHH",3]
["GO:0030252","growth hormone secretion","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"DRD2/CHD7/PTPN11",3]
["GO:0032354","response to follicle-stimulating hormone","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"GCLC/PPARGC1A/SRD5A1",3]
["GO:0035864","response to potassium ion","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"PPARGC1A/SOD1/GNRH1",3]
["GO:0035930","corticosteroid hormone secretion","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"TAC1/POMC/PTPN11",3]
["GO:0045725","positive regulation of glycogen biosynthetic process","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"IGF1/AKT1/INS",3]
["GO:0048521","negative regulation of behavior","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"DRD2/CCK/INS",3]
["GO:0051447","negative regulation of meiotic cell cycle","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"PRKAR1A/DUSP1/LIF",3]
["GO:0051770","positive regulation of nitric-oxide synthase biosynthetic process","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"CCL2/IFNG/LRRK2",3]
["GO:0070886","positive regulation of calcineurin-NFAT signaling cascade","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"IGF1/ERBB3/TNF",3]
["GO:0071380","cellular response to prostaglandin E stimulus","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"SFRP1/AKT1/PRKCE",3]
["GO:0071391","cellular response to estrogen stimulus","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"ESR1/SFRP1/AR",3]
["GO:0072224","metanephric glomerulus development","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"PDGFRB/RET/ADIPOQ",3]
["GO:0072283","metanephric renal vesicle morphogenesis","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"LIF/CTNNB1/GDNF",3]
["GO:0106058","positive regulation of calcineurin-mediated signaling","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"IGF1/ERBB3/TNF",3]
["GO:1900121","negative regulation of receptor binding","3/267","16/18866",0.00136937272593649,0.00336645889739089,0.00120581733725471,"IL10/ATP2A2/ADIPOQ",3]
["GO:0010259","multicellular organism aging","4/267","35/18866",0.00145424609602024,0.00356108423611037,0.00127552934469342,"POU1F1/TP53/LEP/LRRK2",4]
["GO:0021522","spinal cord motor neuron differentiation","4/267","35/18866",0.00145424609602024,0.00356108423611037,0.00127552934469342,"PAX6/GLI2/SHH/PTCH1",4]
["GO:0032735","positive regulation of interleukin-12 production","4/267","35/18866",0.00145424609602024,0.00356108423611037,0.00127552934469342,"IFNG/IL17A/IDO1/AGER",4]
["GO:0033687","osteoblast proliferation","4/267","35/18866",0.00145424609602024,0.00356108423611037,0.00127552934469342,"FGFR2/GATA1/SFRP1/BCL2",4]
["GO:0035909","aorta morphogenesis","4/267","35/18866",0.00145424609602024,0.00356108423611037,0.00127552934469342,"FGF8/SRF/PDGFRB/CHD7",4]
["GO:0042462","eye photoreceptor cell development","4/267","35/18866",0.00145424609602024,0.00356108423611037,0.00127552934469342,"PAX6/VEGFA/NTRK2/PRKCI",4]
["GO:0048333","mesodermal cell differentiation","4/267","35/18866",0.00145424609602024,0.00356108423611037,0.00127552934469342,"FGFR2/FGFR1/KDM6B/KDM6A",4]
["GO:0098751","bone cell development","4/267","35/18866",0.00145424609602024,0.00356108423611037,0.00127552934469342,"EP300/SRF/FBN1/PTPN11",4]
["GO:0045454","cell redox homeostasis","5/267","59/18866",0.00146794424491843,0.00358934653030251,0.0012856524934875,"GCLC/NOS2/NOS3/NQO1/GPX1",5]
["GO:0048008","platelet-derived growth factor receptor signaling pathway","5/267","59/18866",0.00146794424491843,0.00358934653030251,0.0012856524934875,"VEGFA/PDGFRB/PTEN/PTPN11/ADIPOQ",5]
["GO:0060043","regulation of cardiac muscle cell proliferation","5/267","59/18866",0.00146794424491843,0.00358934653030251,0.0012856524934875,"FGFR2/FGFR1/MAPK1/PTEN/ERBB4",5]
["GO:0031345","negative regulation of cell projection organization","9/267","188/18866",0.0014700376471922,0.00359270581127296,0.00128685573979419,"CD38/NGFR/APOE/PLK2/CDK5/PTEN/DCC/LRRK2/HDAC2",9]
["GO:0007605","sensory perception of sound","8/267","152/18866",0.00147193163445791,0.00359474635378665,0.00128758663288257,"COL11A1/FGFR1/COL1A1/COL2A1/SOD1/CHD7/COL11A2/GPX1",8]
["GO:0060218","hematopoietic stem cell differentiation","6/267","87/18866",0.00147231249619341,0.00359474635378665,0.00128758663288257,"GATA1/SFRP1/SRF/KMT2A/TP53/ACE",6]
["GO:0045088","regulation of innate immune response","12/267","307/18866",0.00149149160622009,0.00363979354342959,0.00130372189070738,"CREBBP/GRN/PRKACA/EP300/IFNG/APOE/KRAS/DRD2/FADD/LEP/PTPN11/INS",12]
["GO:0030198","extracellular matrix organization","14/267","395/18866",0.0015723987896298,0.00383536255819325,0.00137377190938268,"TNFRSF1B/COL11A1/TNFRSF1A/TGFB1/COL1A1/TTR/IL6/ADAM10/COL2A1/FBN1/NF1/DPP4/COL11A2/TNF",14]
["GO:0070507","regulation of microtubule cytoskeleton organization","9/267","190/18866",0.00158137294935002,0.00385536871880109,0.00138093782943343,"BRCA1/GSK3B/HDAC6/STMN1/RAC1/PLK2/CTNNB1/MECP2/MAPT",9]
["GO:0032653","regulation of interleukin-10 production","5/267","60/18866",0.00158316929612728,0.00385598258320171,0.00138115770686534,"IDO1/IL6/HLA-DRB1/DLL1/AGER",5]
["GO:0061098","positive regulation of protein tyrosine kinase activity","5/267","60/18866",0.00158316929612728,0.00385598258320171,0.00138115770686534,"ERBB3/NTRK2/ACE/BDNF/CSF1R",5]
["GO:0043062","extracellular structure organization","14/267","396/18866",0.0016098381671669,0.0039190258257749,0.0014037388929747,"TNFRSF1B/COL11A1/TNFRSF1A/TGFB1/COL1A1/TTR/IL6/ADAM10/COL2A1/FBN1/NF1/DPP4/COL11A2/TNF",14]
["GO:0033280","response to vitamin D","4/267","36/18866",0.00161802909223161,0.00393129890876517,0.00140813493543425,"PTGS2/SFRP1/VDR/PENK",4]
["GO:0042554","superoxide anion generation","4/267","36/18866",0.00161802909223161,0.00393129890876517,0.00140813493543425,"TGFB1/CRP/SOD1/MAPT",4]
["GO:0051955","regulation of amino acid transport","4/267","36/18866",0.00161802909223161,0.00393129890876517,0.00140813493543425,"P2RX7/PER2/LEP/CCK",4]
["GO:0071402","cellular response to lipoprotein particle stimulus","4/267","36/18866",0.00161802909223161,0.00393129890876517,0.00140813493543425,"APOE/CDH13/AKT1/LPL",4]
["GO:0006978","DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"BRCA1/BRCA2/TP53",3]
["GO:0009299","mRNA transcription","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"SRF/ATF4/TP53",3]
["GO:0010715","regulation of extracellular matrix disassembly","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"TGFB1/IL6/DPP4",3]
["GO:0030730","sequestering of triglyceride","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"IL1B/LPL/TNF",3]
["GO:0031065","positive regulation of histone deacetylation","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"VEGFA/TP53/LRRK2",3]
["GO:0032305","positive regulation of icosanoid secretion","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"P2RX7/OXT/IL1B",3]
["GO:0033599","regulation of mammary gland epithelial cell proliferation","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"BAX/BRCA2/GPX1",3]
["GO:0035729","cellular response to hepatocyte growth factor stimulus","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"GCLC/CREB1/IL10",3]
["GO:0035855","megakaryocyte development","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"EP300/SRF/PTPN11",3]
["GO:0042249","establishment of planar polarity of embryonic epithelium","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"SFRP1/DVL3/FZD2",3]
["GO:0043117","positive regulation of vascular permeability","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"TGFB1/VEGFA/APOE",3]
["GO:0043923","positive regulation by host of viral transcription","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"SMARCB1/EP300/JUN",3]
["GO:0060263","regulation of respiratory burst","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"GRN/RAC1/INS",3]
["GO:0070242","thymocyte apoptotic process","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"BAX/HIF1A/TP53",3]
["GO:0070875","positive regulation of glycogen metabolic process","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"IGF1/AKT1/INS",3]
["GO:0090185","negative regulation of kidney development","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"SHH/CTNNB1/ADIPOQ",3]
["GO:0097067","cellular response to thyroid hormone stimulus","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"GCLC/GATA1/PPARGC1A",3]
["GO:0099509","regulation of presynaptic cytosolic calcium ion concentration","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"CNR1/CDK5/CALB2",3]
["GO:1902931","negative regulation of alcohol biosynthetic process","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"REST/APOE/SOD1",3]
["GO:1902992","negative regulation of amyloid precursor protein catabolic process","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"IGF1/APOE/NTRK2",3]
["GO:1905331","negative regulation of morphogenesis of an epithelium","3/267","17/18866",0.00164550899493863,0.00395762351239334,0.00141756403123452,"CTNNB1/PTEN/TNF",3]
["GO:0098657","import into cell","10/267","230/18866",0.00167860168651519,0.00403527117032756,0.00144537630965173,"DLG1/IFNG/PER2/GLUL/TOR1A/AKT1/SLC6A3/DRD2/GDNF/PRKN",10]
["GO:1901988","negative regulation of cell cycle phase transition","11/267","270/18866",0.00168031184671966,0.00403743842669455,0.00144615258982661,"BRCA1/BAX/EP300/CCL2/DUSP1/MEN1/TP53/PLK2/CDKN2A/BCL2/PTEN",11]
["GO:0002381","immunoglobulin production involved in immunoglobulin mediated immune response","5/267","61/18866",0.00170490476142048,0.00409062444679119,0.00146520306009429,"TGFB1/IL2/IL10/HLA-DQB1/HLA-DRB1",5]
["GO:0003170","heart valve development","5/267","61/18866",0.00170490476142048,0.00409062444679119,0.00146520306009429,"TNFRSF1B/TNFRSF1A/TGFB1/NOS3/MTOR",5]
["GO:0045843","negative regulation of striated muscle tissue development","5/267","61/18866",0.00170490476142048,0.00409062444679119,0.00146520306009429,"TGFB1/FGF8/S100B/PTEN/DLL1",5]
["GO:0006839","mitochondrial transport","11/267","271/18866",0.00172997144398314,0.00414877397685294,0.00148603138850668,"GCLC/GSK3B/BAX/TSPO/MAPK8/MFN2/TP53/BCL2L1/BCL2/PRKN/LRRK2",11]
["GO:0008360","regulation of cell shape","8/267","156/18866",0.00173515217063387,0.00415920057031922,0.00148976604487806,"DLG1/CCL2/VEGFA/PTK2B/RAC1/S100B/F2/CSF1R",8]
["GO:0051928","positive regulation of calcium ion transport","7/267","122/18866",0.0017677426664936,0.0042352874922277,0.00151701929001547,"BAX/P2RX7/TSPO/CCL2/PDGFRB/CDK5/F2",7]
["GO:0060428","lung epithelium development","4/267","37/18866",0.00179420592170044,0.00429045506084785,0.0015367795225696,"FGFR2/CREB1/SHH/MAP2K1",4]
["GO:0090050","positive regulation of cell migration involved in sprouting angiogenesis","4/267","37/18866",0.00179420592170044,0.00429045506084785,0.0015367795225696,"HDAC9/PTGS2/VEGFA/PLK2",4]
["GO:0097242","amyloid-beta clearance","4/267","37/18866",0.00179420592170044,0.00429045506084785,0.0015367795225696,"IFNG/SRF/APOE/TNF",4]
["GO:1905314","semi-lunar valve development","4/267","37/18866",0.00179420592170044,0.00429045506084785,0.0015367795225696,"TNFRSF1B/TNFRSF1A/TGFB1/NOS3",4]
["GO:0002294","CD4-positive, alpha-beta T cell differentiation involved in immune response","5/267","62/18866",0.00183336796848919,0.0043757200127469,0.00156732020653272,"IL2/IFNG/IL6/IL18/MTOR",5]
["GO:0030888","regulation of B cell proliferation","5/267","62/18866",0.00183336796848919,0.0043757200127469,0.00156732020653272,"CD38/IL2/IL10/BCL2/PAWR",5]
["GO:0034113","heterotypic cell-cell adhesion","5/267","62/18866",0.00183336796848919,0.0043757200127469,0.00156732020653272,"IL1B/IL10/ADIPOQ/AGER/TNF",5]
["GO:0048635","negative regulation of muscle organ development","5/267","62/18866",0.00183336796848919,0.0043757200127469,0.00156732020653272,"TGFB1/FGF8/S100B/PTEN/DLL1",5]
["GO:0030901","midbrain development","6/267","91/18866",0.00185452797502392,0.00441356443245684,0.00158087553537988,"FGFR2/FGFR1/SFRP1/SHH/OTX2/CTNNB1",6]
["GO:0045682","regulation of epidermis development","6/267","91/18866",0.00185452797502392,0.00441356443245684,0.00158087553537988,"NGFR/VDR/CTNNB1/PTCH1/DLL1/TNF",6]
["GO:0048477","oogenesis","6/267","91/18866",0.00185452797502392,0.00441356443245684,0.00158087553537988,"IGF1/PTK2B/BRCA2/KMT2D/CTNNB1/BCL2",6]
["GO:0051492","regulation of stress fiber assembly","6/267","91/18866",0.00185452797502392,0.00441356443245684,0.00158087553537988,"TAC1/SFRP1/STMN1/RAC1/PIK3R1/MTOR",6]
["GO:0060021","roof of mouth development","6/267","91/18866",0.00185452797502392,0.00441356443245684,0.00158087553537988,"DLG1/COL2A1/SHH/CHD7/FZD2/COL11A2",6]
["GO:0060333","interferon-gamma-mediated signaling pathway","6/267","91/18866",0.00185452797502392,0.00441356443245684,0.00158087553537988,"IFNG/TP53/NCAM1/HLA-DQB1/HLA-DRB1/HLA-DQA1",6]
["GO:0050864","regulation of B cell activation","9/267","195/18866",0.0018895322946606,0.00449472832169622,0.00160994727746464,"CD38/XBP1/SFRP1/TGFB1/IL2/IL6/IL10/BCL2/PAWR",9]
["GO:0007178","transmembrane receptor protein serine/threonine kinase signaling pathway","13/267","359/18866",0.00189882192664753,0.00451467518083387,0.00161709195657852,"CREBBP/SIRT1/EP300/MAPK3/SFRP1/TGFB1/CREB1/MEN1/TP53/SHH/FBN1/FOS/JUN",13]
["GO:0031929","TOR signaling","7/267","124/18866",0.00193987908220713,0.0046099777582586,0.00165122797417044,"SIRT1/HIF1A/TSC2/PIK3CA/AKT1/LEP/MTOR",7]
["GO:0007281","germ cell development","11/267","275/18866",0.00194075170195465,0.0046099777582586,0.00165122797417044,"IGF1/PRKACA/BAX/PTK2B/BRCA2/AKT1/KMT2D/CTNNB1/BCL2L1/BCL2/MTOR",11]
["GO:0006349","regulation of gene expression by genetic imprinting","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"BRCA1/PRMT7/MECP2",3]
["GO:0007221","positive regulation of transcription of Notch receptor target","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"CREBBP/NOTCH3/EP300",3]
["GO:0010832","negative regulation of myotube differentiation","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"HDAC4/XBP1/BDNF",3]
["GO:0031293","membrane protein intracellular domain proteolysis","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"NGFR/TGFB1/ADAM10",3]
["GO:0035994","response to muscle stretch","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"FOS/JUN/DMD",3]
["GO:0042772","DNA damage response, signal transduction resulting in transcription","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"BRCA1/BRCA2/TP53",3]
["GO:0043217","myelin maintenance","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"SOD1/AKT1/PTEN",3]
["GO:0045721","negative regulation of gluconeogenesis","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"EP300/ADIPOQ/INS",3]
["GO:0046885","regulation of hormone biosynthetic process","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"REST/HIF1A/PPARGC1A",3]
["GO:0060033","anatomical structure regression","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"GLI2/SLC6A3/DRD2",3]
["GO:0071318","cellular response to ATP","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"PTGS2/P2RX7/SOD1",3]
["GO:0071605","monocyte chemotactic protein-1 production","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"IL1B/ADIPOQ/AGER",3]
["GO:0071637","regulation of monocyte chemotactic protein-1 production","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"IL1B/ADIPOQ/AGER",3]
["GO:2000831","regulation of steroid hormone secretion","3/267","18/18866",0.00195408017823705,0.00461092737709715,0.00165156811403081,"TAC1/POMC/PTPN11",3]
["GO:0031341","regulation of cell killing","6/267","92/18866",0.0019608433082406,0.00462470034862793,0.00165650139507286,"NOS2/P2RX7/IFNG/FADD/LEP/AGER",6]
["GO:0002287","alpha-beta T cell activation involved in immune response","5/267","63/18866",0.00196877736111568,0.00463684215285404,0.00166085041536025,"IL2/IFNG/IL6/IL18/MTOR",5]
["GO:0002293","alpha-beta T cell differentiation involved in immune response","5/267","63/18866",0.00196877736111568,0.00463684215285404,0.00166085041536025,"IL2/IFNG/IL6/IL18/MTOR",5]
["GO:0032613","interleukin-10 production","5/267","63/18866",0.00196877736111568,0.00463684215285404,0.00166085041536025,"IDO1/IL6/HLA-DRB1/DLL1/AGER",5]
["GO:0030224","monocyte differentiation","4/267","38/18866",0.00198324983017232,0.00465993713037666,0.00166912270536856,"VEGFA/JUN/CSF1R/HLA-DRB1",4]
["GO:0045923","positive regulation of fatty acid metabolic process","4/267","38/18866",0.00198324983017232,0.00465993713037666,0.00166912270536856,"PTGS2/PPARGC1A/IL1B/ADIPOQ",4]
["GO:0060045","positive regulation of cardiac muscle cell proliferation","4/267","38/18866",0.00198324983017232,0.00465993713037666,0.00166912270536856,"FGFR2/FGFR1/MAPK1/ERBB4",4]
["GO:1903131","mononuclear cell differentiation","4/267","38/18866",0.00198324983017232,0.00465993713037666,0.00166912270536856,"VEGFA/JUN/CSF1R/HLA-DRB1",4]
["GO:1905898","positive regulation of response to endoplasmic reticulum stress","4/267","38/18866",0.00198324983017232,0.00465993713037666,0.00166912270536856,"BAX/SIRT1/XBP1/PIK3R1",4]
["GO:0045185","maintenance of protein location","6/267","93/18866",0.00207170575696419,0.00486320020899023,0.00174192862746253,"TSPO/SYNE1/IL10/AKT1/CDK5/FBN1",6]
["GO:1903035","negative regulation of response to wounding","6/267","93/18866",0.00207170575696419,0.00486320020899023,0.00174192862746253,"APOE/NOS3/PTEN/F2/AGER/TNF",6]
["GO:0001947","heart looping","5/267","64/18866",0.00211135234650596,0.0049446445901052,0.0017711008377178,"HIF1A/FGF8/SRF/SHH/DLL1",5]
["GO:0046173","polyol biosynthetic process","5/267","64/18866",0.00211135234650596,0.0049446445901052,0.0017711008377178,"POU1F1/PTK2B/CYP27A1/CYP3A4/LEP",5]
["GO:0070265","necrotic cell death","5/267","64/18866",0.00211135234650596,0.0049446445901052,0.0017711008377178,"BAX/TSPO/TP53/FADD/TNF",5]
["GO:1905268","negative regulation of chromatin organization","5/267","64/18866",0.00211135234650596,0.0049446445901052,0.0017711008377178,"BRCA1/SIRT1/SMARCB1/DNMT1/PAX5",5]
["GO:2000401","regulation of lymphocyte migration","5/267","64/18866",0.00211135234650596,0.0049446445901052,0.0017711008377178,"CCL2/PTK2B/ADAM10/AKT1/FADD",5]
["GO:0034767","positive regulation of ion transmembrane transport","8/267","161/18866",0.00211504510418369,0.00495097056033248,0.001773366709605,"ABCB1/BAX/P2RX7/CCL2/IFNG/CDK5/F2/DMD",8]
["GO:0045814","negative regulation of gene expression, epigenetic","7/267","126/18866",0.00212472781197011,0.00497130551319904,0.00178065039833138,"SIRT1/DNMT1/KMT2D/MECP2/MTHFR/HDAC2/HOTAIR",7]
["GO:0002831","regulation of response to biotic stimulus","14/267","409/18866",0.00216815762671802,0.00507054380805765,0.00181619613351112,"CREBBP/GRN/PRKACA/EP300/MAPK3/IFNG/IL1B/APOE/KRAS/DRD2/FADD/LEP/PTPN11/INS",14]
["GO:0016601","Rac protein signal transduction","4/267","39/18866",0.00218563048832531,0.00508894731013235,0.00182278800424064,"KRAS/RAC1/CDH13/NF1",4]
["GO:0033146","regulation of intracellular estrogen receptor signaling pathway","4/267","39/18866",0.00218563048832531,0.00508894731013235,0.00182278800424064,"BRCA1/ESR1/KMT2D/AR",4]
["GO:0035886","vascular associated smooth muscle cell differentiation","4/267","39/18866",0.00218563048832531,0.00508894731013235,0.00182278800424064,"SOD2/SRF/VEGFA/DNMT1",4]
["GO:0042092","type 2 immune response","4/267","39/18866",0.00218563048832531,0.00508894731013235,0.00182278800424064,"IDO1/IL6/IL10/IL18",4]
["GO:0045022","early endosome to late endosome transport","4/267","39/18866",0.00218563048832531,0.00508894731013235,0.00182278800424064,"MAPK1/MAPK3/MAP2K2/MAP2K1",4]
["GO:0046329","negative regulation of JNK cascade","4/267","39/18866",0.00218563048832531,0.00508894731013235,0.00182278800424064,"SFRP1/MEN1/AKT1/PRKN",4]
["GO:0060416","response to growth hormone","4/267","39/18866",0.00218563048832531,0.00508894731013235,0.00182278800424064,"AKT1/SRD5A1/PIK3R1/PRL",4]
["GO:1904706","negative regulation of vascular associated smooth muscle cell proliferation","4/267","39/18866",0.00218563048832531,0.00508894731013235,0.00182278800424064,"SOD2/IL10/PTEN/ADIPOQ",4]
["GO:2000279","negative regulation of DNA biosynthetic process","4/267","39/18866",0.00218563048832531,0.00508894731013235,0.00182278800424064,"DUSP1/MEN1/TP53/ADIPOQ",4]
["GO:0060349","bone morphogenesis","6/267","94/18866",0.00218723831915562,0.00508894731013235,0.00182278800424064,"FGFR2/FGFR3/GNAS/COL1A1/COL2A1/INPPL1",6]
["GO:1904035","regulation of epithelial cell apoptotic process","6/267","94/18866",0.00218723831915562,0.00508894731013235,0.00182278800424064,"CCL2/PPARGC1A/IL6/PRKCI/MTOR/TNF",6]
["GO:1903305","regulation of regulated secretory pathway","8/267","162/18866",0.0021983204503705,0.00511234932869115,0.00183117027194836,"GSK3B/REST/HTR2A/CNR1/DRD2/CDK5/ATP2A2/LRRK2",8]
["GO:0017015","regulation of transforming growth factor beta receptor signaling pathway","7/267","127/18866",0.00222211205606988,0.00516286900695995,0.00184926569678075,"CREBBP/SIRT1/EP300/TGFB1/MEN1/TP53/FBN1",7]
["GO:0019079","viral genome replication","7/267","127/18866",0.00222211205606988,0.00516286900695995,0.00184926569678075,"SMARCB1/CCL2/VCP/CXCL8/BCL2/PRKN/TNF",7]
["GO:0032729","positive regulation of interferon-gamma production","5/267","65/18866",0.00226131314381894,0.00525150536143626,0.00188101396883641,"IL2/IL1B/IL18/FADD/TNF",5]
["GO:0007088","regulation of mitotic nuclear division","8/267","163/18866",0.00228415140224117,0.00529106022436064,0.00189518195393313,"IGF1/ATRX/FGF8/PDGFRB/IL1A/DUSP1/IL1B/INS",8]
["GO:0002862","negative regulation of inflammatory response to antigenic stimulus","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"IL10/HLA-DRB1/GPX1",3]
["GO:0010544","negative regulation of platelet activation","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"APOE/NOS3/F2",3]
["GO:0010744","positive regulation of macrophage derived foam cell differentiation","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"APOB/IL18/LPL",3]
["GO:0010759","positive regulation of macrophage chemotaxis","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"MAPK1/MAPK3/CSF1R",3]
["GO:0035728","response to hepatocyte growth factor","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"GCLC/CREB1/IL10",3]
["GO:0042053","regulation of dopamine metabolic process","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"COMT/SLC6A3/PRKN",3]
["GO:0042069","regulation of catecholamine metabolic process","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"COMT/SLC6A3/PRKN",3]
["GO:0044320","cellular response to leptin stimulus","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"SIRT1/PTEN/LEP",3]
["GO:0055003","cardiac myofibril assembly","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"SRF/PDGFRB/NEB",3]
["GO:0060602","branch elongation of an epithelium","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"FGFR2/ESR1/SHH",3]
["GO:0070233","negative regulation of T cell apoptotic process","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"HIF1A/IDO1/FADD",3]
["GO:0072077","renal vesicle morphogenesis","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"LIF/CTNNB1/GDNF",3]
["GO:0150079","negative regulation of neuroinflammatory response","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"IGF1/TNFRSF1B/GRN",3]
["GO:2000010","positive regulation of protein localization to cell surface","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"AKT1/ERBB4/TNF",3]
["GO:2000647","negative regulation of stem cell proliferation","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"TP53/BDNF/NF1",3]
["GO:2000757","negative regulation of peptidyl-lysine acetylation","3/267","19/18866",0.00229636040580603,0.00529106022436064,0.00189518195393313,"BRCA1/SIRT1/HDAC2",3]
["GO:0003073","regulation of systemic arterial blood pressure","6/267","95/18866",0.00230756490304711,0.00531197397921357,0.00190267296123707,"SOD2/DRD2/ACE/NOS3/MECP2/AR",6]
["GO:0048814","regulation of dendrite morphogenesis","6/267","95/18866",0.00230756490304711,0.00531197397921357,0.00190267296123707,"GSK3B/ADAM10/PDLIM5/CDK5/PTEN/LRRK2",6]
["GO:0098727","maintenance of cell number","8/267","164/18866",0.00237259181781874,0.00545914790155252,0.001955388551285,"IGF1/REST/SFRP1/SMC3/LIF/CTNNB1/MED12/DLL1",8]
["GO:0034341","response to interferon-gamma","9/267","202/18866",0.00239971924856769,0.00551114649224678,0.00197401370135606,"NOS2/CCL2/IFNG/FLNB/TP53/NCAM1/HLA-DQB1/HLA-DRB1/HLA-DQA1",9]
["GO:0000096","sulfur amino acid metabolic process","4/267","40/18866",0.00240181349231504,0.00551114649224678,0.00197401370135606,"GCLC/COMT/MTR/MTHFR",4]
["GO:0008207","C21-steroid hormone metabolic process","4/267","40/18866",0.00240181349231504,0.00551114649224678,0.00197401370135606,"REST/TSPO/PPARGC1A/SRD5A1",4]
["GO:0032892","positive regulation of organic acid transport","4/267","40/18866",0.00240181349231504,0.00551114649224678,0.00197401370135606,"P2RX7/OXT/IL1B/CCK",4]
["GO:0043902","positive regulation of multi-organism process","4/267","40/18866",0.00240181349231504,0.00551114649224678,0.00197401370135606,"HDAC4/OXT/VEGFA/HDAC2",4]
["GO:1902742","apoptotic process involved in development","4/267","40/18866",0.00240181349231504,0.00551114649224678,0.00197401370135606,"TNFRSF1B/TNFRSF1A/BAX/VDR",4]
["GO:0006360","transcription by RNA polymerase I","5/267","66/18866",0.0024188806340292,0.00554521166469595,0.00198621535798927,"SMARCB1/MAPK3/TBP/ATF4/MTOR",5]
["GO:0045669","positive regulation of osteoblast differentiation","5/267","66/18866",0.0024188806340292,0.00554521166469595,0.00198621535798927,"IGF1/GNAS/IL6/IL6R/CTNNB1",5]
["GO:1903844","regulation of cellular response to transforming growth factor beta stimulus","7/267","129/18866",0.00242719187205592,0.00556171134335714,0.00199212530645299,"CREBBP/SIRT1/EP300/TGFB1/MEN1/TP53/FBN1",7]
["GO:0035710","CD4-positive, alpha-beta T cell activation","6/267","97/18866",0.0025631000159293,0.0058704396236399,0.00210270735251757,"IL2/IFNG/IL6/IL18/MTOR/AGER",6]
["GO:0045123","cellular extravasation","5/267","67/18866",0.0025842762112531,0.00591351563830738,0.0021181365637122,"CCL2/FADD/LEP/AGER/TNF",5]
["GO:0048663","neuron fate commitment","5/267","67/18866",0.0025842762112531,0.00591351563830738,0.0021181365637122,"PAX6/GLI2/NOTCH3/SHH/DLL1",5]
["GO:0038083","peptidyl-tyrosine autophosphorylation","4/267","41/18866",0.00263225989065784,0.00601779928299203,0.0021554894709021,"MAPK3/VEGFA/PTK2B/ACE",4]
["GO:1900117","regulation of execution phase of apoptosis","4/267","41/18866",0.00263225989065784,0.00601779928299203,0.0021554894709021,"BAX/IL6/TP53/BCL2L1",4]
["GO:0003231","cardiac ventricle development","7/267","131/18866",0.00264654986100968,0.00604769952220655,0.00216619930813221,"COL11A1/FGFR2/HIF1A/TGFB1/NOS3/CHD7/FZD2",7]
["GO:0034250","positive regulation of cellular amide metabolic process","8/267","167/18866",0.00265411557981344,0.00606221367337992,0.00217139806910148,"TNFRSF1A/MAPK1/MAPK3/IFNG/PTK2B/IL6/MTOR/TNF",8]
["GO:0002544","chronic inflammatory response","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"IDO1/IL10/TNF",3]
["GO:0002689","negative regulation of leukocyte chemotaxis","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"CCL2/DUSP1/DPP4",3]
["GO:0002726","positive regulation of T cell cytokine production","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"IL1B/IL6/IL18",3]
["GO:0007620","copulation","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"TAC1/OXT/CNR1",3]
["GO:0030903","notochord development","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"GLI2/COL2A1/KDM6A",3]
["GO:0031998","regulation of fatty acid beta-oxidation","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"CNR1/AKT1/MTOR",3]
["GO:0032303","regulation of icosanoid secretion","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"P2RX7/OXT/IL1B",3]
["GO:0048670","regulation of collateral sprouting","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"NGF/BDNF/DCC",3]
["GO:0051767","nitric-oxide synthase biosynthetic process","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"CCL2/IFNG/LRRK2",3]
["GO:0051769","regulation of nitric-oxide synthase biosynthetic process","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"CCL2/IFNG/LRRK2",3]
["GO:0060231","mesenchymal to epithelial transition","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"LIF/CTNNB1/GDNF",3]
["GO:0071243","cellular response to arsenic-containing substance","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"ATF4/ATF3/VCP",3]
["GO:0072087","renal vesicle development","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"LIF/CTNNB1/GDNF",3]
["GO:2000193","positive regulation of fatty acid transport","3/267","20/18866",0.00267355033433069,0.0060677440087787,0.00217337895599418,"P2RX7/OXT/IL1B",3]
["GO:0006835","dicarboxylic acid transport","6/267","98/18866",0.0026985604550079,0.00612172301310969,0.00219271346185151,"P2RX7/PER2/NTRK2/BDNF/CCK/NF1",6]
["GO:0050766","positive regulation of phagocytosis","5/267","68/18866",0.0027577216356593,0.00625308997586143,0.00223976722548169,"CCL2/IFNG/IL1B/SOD1/TNF",5]
["GO:0007044","cell-substrate junction assembly","6/267","99/18866",0.00283931863291235,0.00643226766521387,0.00230394610627476,"SFRP1/VEGFA/PTK2B/RAC1/BCL2/PTEN",6]
["GO:0043473","pigmentation","6/267","99/18866",0.00283931863291235,0.00643226766521387,0.00230394610627476,"BAX/POMC/DRD2/BCL2/NF1/MC1R",6]
["GO:0038095","Fc-epsilon receptor signaling pathway","8/267","169/18866",0.00285585400084552,0.00646679320917083,0.00231631266138515,"MAPK1/MAPK3/MAPK8/PIK3CA/RAC1/PIK3R1/FOS/JUN",8]
["GO:0000266","mitochondrial fission","4/267","42/18866",0.00287742573659005,0.00649795870773139,0.00232747569638244,"PPARGC1A/PRKN/MAPT/LRRK2",4]
["GO:0001709","cell fate determination","4/267","42/18866",0.00287742573659005,0.00649795870773139,0.00232747569638244,"PAX6/CTNNB1/PTCH1/DLL1",4]
["GO:0072595","maintenance of protein localization in organelle","4/267","42/18866",0.00287742573659005,0.00649795870773139,0.00232747569638244,"TSPO/SYNE1/AKT1/CDK5",4]
["GO:0098927","vesicle-mediated transport between endosomal compartments","4/267","42/18866",0.00287742573659005,0.00649795870773139,0.00232747569638244,"MAPK1/MAPK3/MAP2K2/MAP2K1",4]
["GO:1900371","regulation of purine nucleotide biosynthetic process","4/267","42/18866",0.00287742573659005,0.00649795870773139,0.00232747569638244,"NOS2/PPARGC1A/NOS3/VCP",4]
["GO:1904037","positive regulation of epithelial cell apoptotic process","4/267","42/18866",0.00287742573659005,0.00649795870773139,0.00232747569638244,"CCL2/PPARGC1A/IL6/PRKCI",4]
["GO:0006959","humoral immune response","13/267","377/18866",0.00289942792859447,0.00654468519325144,0.00234421245392691,"CCL2/IFNG/IL1B/CRP/IL6/CXCL8/BCL2/HLA-DQB1/F2/PAX5/HLA-DRB1/IFNA1/TNF",13]
["GO:0061371","determination of heart left/right asymmetry","5/267","69/18866",0.00293943888807806,0.00662900558634767,0.00237441481046195,"HIF1A/FGF8/SRF/SHH/DLL1",5]
["GO:2000573","positive regulation of DNA biosynthetic process","5/267","69/18866",0.00293943888807806,0.00662900558634767,0.00237441481046195,"MAPK1/MAPK3/PDGFRB/PTK2B/CTNNB1",5]
["GO:0002702","positive regulation of production of molecular mediator of immune response","6/267","100/18866",0.00298550224243387,0.00672074512915793,0.00240727460011159,"XBP1/TGFB1/IL2/IL1B/IL6/IL18",6]
["GO:0030219","megakaryocyte differentiation","6/267","100/18866",0.00298550224243387,0.00672074512915793,0.00240727460011159,"EP300/GATA1/SRF/KMT2A/KMT2D/PTPN11",6]
["GO:0035282","segmentation","6/267","100/18866",0.00298550224243387,0.00672074512915793,0.00240727460011159,"EP300/SFRP1/TP53/KDM6A/MED12/DLL1",6]
["GO:0045807","positive regulation of endocytosis","6/267","100/18866",0.00298550224243387,0.00672074512915793,0.00240727460011159,"VEGFA/APOE/TOR1A/DRD2/LRRK2/DLL1",6]
["GO:0002363","alpha-beta T cell lineage commitment","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"IL6/BCL2/MTOR",3]
["GO:0003177","pulmonary valve development","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"TNFRSF1B/TNFRSF1A/NOS3",3]
["GO:0010310","regulation of hydrogen peroxide metabolic process","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"HDAC6/RAC1/HP",3]
["GO:0010829","negative regulation of glucose transmembrane transport","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"IL1B/LEP/TNF",3]
["GO:0014821","phasic smooth muscle contraction","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"DLG1/DRD2/GDNF",3]
["GO:0030502","negative regulation of bone mineralization","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"HIF1A/GATA1/PTK2B",3]
["GO:0035929","steroid hormone secretion","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"TAC1/POMC/PTPN11",3]
["GO:0043984","histone H4-K16 acetylation","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"BRCA1/SIRT1/KMT2A",3]
["GO:0045943","positive regulation of transcription by RNA polymerase I","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"SMARCB1/ATF4/MTOR",3]
["GO:0048485","sympathetic nervous system development","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"CTNNB1/GDNF/NF1",3]
["GO:0051797","regulation of hair follicle development","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"NGFR/CTNNB1/TNF",3]
["GO:0061042","vascular wound healing","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"XBP1/VEGFA/TNF",3]
["GO:1903978","regulation of microglial cell activation","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"GRN/IL6/LRRK2",3]
["GO:2000269","regulation of fibroblast apoptotic process","3/267","21/18866",0.00308677938687619,0.00690514761589283,0.00247332492845814,"SFRP1/PIK3CA/TP53",3]
["GO:0030100","regulation of endocytosis","9/267","210/18866",0.00311080345951124,0.0069557732527271,0.00249145830613034,"TSC2/VEGFA/APOE/RAC1/TOR1A/CDH13/DRD2/LRRK2/DLL1",9]
["GO:0003143","embryonic heart tube morphogenesis","5/267","70/18866",0.00312965002641612,0.00698165953371996,0.00250073040104361,"HIF1A/FGF8/SRF/SHH/DLL1",5]
["GO:0007215","glutamate receptor signaling pathway","6/267","101/18866",0.00313723957782741,0.00698165953371996,0.00250073040104361,"DLG1/CCL2/PPARGC1A/IFNG/OPRM1/PTK2B",6]
["GO:0001953","negative regulation of cell-matrix adhesion","4/267","43/18866",0.00313776166506461,0.00698165953371996,0.00250073040104361,"PIK3R1/CDKN2A/PTEN/NF1",4]
["GO:0010470","regulation of gastrulation","4/267","43/18866",0.00313776166506461,0.00698165953371996,0.00250073040104361,"FGFR1/IL10/OTX2/ADIPOQ",4]
["GO:0030808","regulation of nucleotide biosynthetic process","4/267","43/18866",0.00313776166506461,0.00698165953371996,0.00250073040104361,"NOS2/PPARGC1A/NOS3/VCP",4]
["GO:0046717","acid secretion","4/267","43/18866",0.00313776166506461,0.00698165953371996,0.00250073040104361,"P2RX7/OXT/DRD2/NF1",4]
["GO:0050850","positive regulation of calcium-mediated signaling","4/267","43/18866",0.00313776166506461,0.00698165953371996,0.00250073040104361,"IGF1/ERBB3/CDH13/TNF",4]
["GO:0051154","negative regulation of striated muscle cell differentiation","4/267","43/18866",0.00313776166506461,0.00698165953371996,0.00250073040104361,"HDAC4/XBP1/BDNF/DLL1",4]
["GO:0070296","sarcoplasmic reticulum calcium ion transport","4/267","43/18866",0.00313776166506461,0.00698165953371996,0.00250073040104361,"PRKACA/CHD7/ATP2A2/DMD",4]
["GO:0071364","cellular response to epidermal growth factor stimulus","4/267","43/18866",0.00313776166506461,0.00698165953371996,0.00250073040104361,"COL1A1/AKT1/ERBB4/PTPN11",4]
["GO:0090317","negative regulation of intracellular protein transport","4/267","43/18866",0.00313776166506461,0.00698165953371996,0.00250073040104361,"CDK5/ADIPOQ/LRRK2/NF1",4]
["GO:0051346","negative regulation of hydrolase activity","15/267","473/18866",0.00316015233890718,0.00702834771855838,0.00251745343983275,"HDAC9/NGFR/PTGS2/GSK3B/SIRT1/VEGFA/PPP1R1B/NGF/TP53/AKT1/NOS3/LRRK2/SERPINA3/TNF/GPX1",15]
["GO:1901991","negative regulation of mitotic cell cycle phase transition","10/267","251/18866",0.00316383733234866,0.00703341041870743,0.00251926682648,"BRCA1/BAX/EP300/CCL2/DUSP1/TP53/PLK2/CDKN2A/BCL2/PTEN",10]
["GO:0001906","cell killing","8/267","172/18866",0.00318067305046708,0.0070645465039956,0.0025304193260646,"NOS2/P2RX7/IFNG/IL18/FADD/LEP/F2/AGER",8]
["GO:0015698","inorganic anion transport","8/267","172/18866",0.00318067305046708,0.0070645465039956,0.0025304193260646,"GABRA3/TG/FGFR1/ABCB1/TSPO/ATF4/ANO10/MTOR",8]
["GO:0110020","regulation of actomyosin structure organization","6/267","102/18866",0.0032946594824961,0.00731121546493468,0.00261877261322146,"TAC1/SFRP1/STMN1/RAC1/PIK3R1/MTOR",6]
["GO:0150115","cell-substrate junction organization","6/267","102/18866",0.0032946594824961,0.00731121546493468,0.00261877261322146,"SFRP1/VEGFA/PTK2B/RAC1/BCL2/PTEN",6]
["GO:0002292","T cell differentiation involved in immune response","5/267","71/18866",0.00332857704397711,0.00737664677344772,0.00264220917033061,"IL2/IFNG/IL6/IL18/MTOR",5]
["GO:0033627","cell adhesion mediated by integrin","5/267","71/18866",0.00332857704397711,0.00737664677344772,0.00264220917033061,"LIF/RET/FBN1/PTPN11/DPP4",5]
["GO:0046579","positive regulation of Ras protein signal transduction","5/267","71/18866",0.00332857704397711,0.00737664677344772,0.00264220917033061,"IGF1/PDGFRB/KRAS/NGF/RAC1",5]
["GO:0032273","positive regulation of protein polymerization","7/267","137/18866",0.00339678195030356,0.00752445975060588,0.00269515366065743,"DLG1/PTK2B/RAC1/MECP2/PRKCE/MAPT/MTOR",7]
["GO:0042088","T-helper 1 type immune response","4/267","44/18866",0.00341371249356827,0.00755525996471027,0.00270618585599687,"IL1B/IL18/HLA-DRB1/MTOR",4]
["GO:1905521","regulation of macrophage migration","4/267","44/18866",0.00341371249356827,0.00755525996471027,0.00270618585599687,"MAPK1/MAPK3/PTK2B/CSF1R",4]
["GO:0002042","cell migration involved in sprouting angiogenesis","6/267","103/18866",0.00345789129654264,0.00764625830099087,0.00273878015608873,"HDAC9/PTGS2/SRF/VEGFA/AKT1/PLK2",6]
["GO:0070498","interleukin-1-mediated signaling pathway","6/267","103/18866",0.00345789129654264,0.00764625830099087,0.00273878015608873,"VRK2/MAPK3/IL1A/IL1B/IL6/SQSTM1",6]
["GO:0019058","viral life cycle","12/267","341/18866",0.00353243502470841,0.0077903749169213,0.00279040066279092,"SMARCB1/HTR2A/CCL2/APOE/NCAM1/VCP/CXCL8/BCL2/PRKN/HLA-DRB1/DPP4/TNF",12]
["GO:0061515","myeloid cell development","5/267","72/18866",0.00353644172978073,0.0077903749169213,0.00279040066279092,"EP300/GATA1/SRF/FBN1/PTPN11",5]
["GO:0006925","inflammatory cell apoptotic process","3/267","22/18866",0.00353710793844594,0.0077903749169213,0.00279040066279092,"SIRT1/IL6/CDKN2A",3]
["GO:0010560","positive regulation of glycoprotein biosynthetic process","3/267","22/18866",0.00353710793844594,0.0077903749169213,0.00279040066279092,"IGF1/CTNNB1/PAWR",3]
["GO:0021513","spinal cord dorsal/ventral patterning","3/267","22/18866",0.00353710793844594,0.0077903749169213,0.00279040066279092,"PAX6/GLI2/SHH",3]
["GO:0051152","positive regulation of smooth muscle cell differentiation","3/267","22/18866",0.00353710793844594,0.0077903749169213,0.00279040066279092,"SIRT1/SOD2/SHH",3]
["GO:0099633","protein localization to postsynaptic specialization membrane","3/267","22/18866",0.00353710793844594,0.0077903749169213,0.00279040066279092,"DLG1/ADAM10/GPC6",3]
["GO:0099645","neurotransmitter receptor localization to postsynaptic specialization membrane","3/267","22/18866",0.00353710793844594,0.0077903749169213,0.00279040066279092,"DLG1/ADAM10/GPC6",3]
["GO:2000479","regulation of cAMP-dependent protein kinase activity","3/267","22/18866",0.00353710793844594,0.0077903749169213,0.00279040066279092,"SIRT1/PRKAR1A/ADIPOQ",3]
["GO:0002027","regulation of heart rate","6/267","104/18866",0.00362706480422731,0.00798146080542396,0.00285884488988064,"TAC1/PRKACA/OXT/DRD2/ATP2A2/DMD",6]
["GO:0007200","phospholipase C-activating G protein-coupled receptor signaling pathway","6/267","104/18866",0.00362706480422731,0.00798146080542396,0.00285884488988064,"ESR1/HTR2A/OPRM1/GRPR/DRD2/F2",6]
["GO:0008016","regulation of heart contraction","10/267","256/18866",0.00363858372581064,0.00800328129646367,0.00286666067709357,"TAC1/HDAC4/PRKACA/DLG1/OXT/IL2/DRD2/NOS3/ATP2A2/DMD",10]
["GO:0035304","regulation of protein dephosphorylation","7/267","139/18866",0.00367978532988473,0.00809034264734233,0.00289784480542963,"GSK3B/TGFB1/PDGFRB/PPP1R1B/DRD2/MTOR/TNF",7]
["GO:0002639","positive regulation of immunoglobulin production","4/267","45/18866",0.00370571684596437,0.00812945703510548,0.0029118550186354,"XBP1/TGFB1/IL2/IL6",4]
["GO:0034105","positive regulation of tissue remodeling","4/267","45/18866",0.00370571684596437,0.00812945703510548,0.0029118550186354,"BAX/IL2/VDR/IL18",4]
["GO:0035315","hair cell differentiation","4/267","45/18866",0.00370571684596437,0.00812945703510548,0.0029118550186354,"FGFR1/SOD1/CTNNB1/DLL1",4]
["GO:0045911","positive regulation of DNA recombination","4/267","45/18866",0.00370571684596437,0.00812945703510548,0.0029118550186354,"FUS/TGFB1/IL2/TIMELESS",4]
["GO:0051204","protein insertion into mitochondrial membrane","4/267","45/18866",0.00370571684596437,0.00812945703510548,0.0029118550186354,"BAX/MAPK8/TP53/BCL2",4]
["GO:0003208","cardiac ventricle morphogenesis","5/267","73/18866",0.00375346553096769,0.00821976026145687,0.00294420034031122,"COL11A1/FGFR2/HIF1A/TGFB1/CHD7",5]
["GO:0051155","positive regulation of striated muscle cell differentiation","5/267","73/18866",0.00375346553096769,0.00821976026145687,0.00294420034031122,"IGF1/TGFB1/SHH/BCL2/MTOR",5]
["GO:0072401","signal transduction involved in DNA integrity checkpoint","5/267","73/18866",0.00375346553096769,0.00821976026145687,0.00294420034031122,"BRCA1/BAX/EP300/TP53/PLK2",5]
["GO:0072422","signal transduction involved in DNA damage checkpoint","5/267","73/18866",0.00375346553096769,0.00821976026145687,0.00294420034031122,"BRCA1/BAX/EP300/TP53/PLK2",5]
["GO:0097006","regulation of plasma lipoprotein particle levels","6/267","105/18866",0.00380231018137052,0.00832307528960237,0.00298120630293662,"PRKACA/APOB/APOE/ALB/LPL/ADIPOQ",6]
["GO:0060048","cardiac muscle contraction","7/267","140/18866",0.00382783905201571,0.00837528500732448,0.0029999070756837,"HDAC4/PRKACA/DLG1/PIK3CA/ATP2A2/MTOR/DMD",7]
["GO:0006635","fatty acid beta-oxidation","5/267","74/18866",0.00397986941737087,0.00869649365467517,0.00311495941039416,"CNR1/AKT1/LEP/ADIPOQ/MTOR",5]
["GO:0072395","signal transduction involved in cell cycle checkpoint","5/267","74/18866",0.00397986941737087,0.00869649365467517,0.00311495941039416,"BRCA1/BAX/EP300/TP53/PLK2",5]
["GO:1903036","positive regulation of response to wounding","5/267","74/18866",0.00397986941737087,0.00869649365467517,0.00311495941039416,"GRN/XBP1/PRKCE/F2/MTOR",5]
["GO:0019395","fatty acid oxidation","6/267","106/18866",0.00398375794273753,0.00870118259321457,0.00311663892098866,"PPARGC1A/CNR1/AKT1/LEP/ADIPOQ/MTOR",6]
["GO:0001754","eye photoreceptor cell differentiation","4/267","46/18866",0.00401420679858759,0.00874270053795748,0.00313151005386273,"PAX6/VEGFA/NTRK2/PRKCI",4]
["GO:0014014","negative regulation of gliogenesis","4/267","46/18866",0.00401420679858759,0.00874270053795748,0.00313151005386273,"TSPO/CTNNB1/F2/NF1",4]
["GO:0006359","regulation of transcription by RNA polymerase III","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"BRCA1/AR/MTOR",3]
["GO:0010226","response to lithium ion","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"PTGS2/PTK2B/SHH",3]
["GO:0032693","negative regulation of interleukin-10 production","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"IDO1/DLL1/AGER",3]
["GO:0035743","CD4-positive, alpha-beta T cell cytokine production","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"IL1B/IL6/IL18",3]
["GO:0043586","tongue development","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"CTNNB1/BDNF/HDAC2",3]
["GO:0051151","negative regulation of smooth muscle cell differentiation","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"DNMT1/SHH/MECP2",3]
["GO:0070977","bone maturation","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"IGF1/FGFR3/LEP",3]
["GO:0071218","cellular response to misfolded protein","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"HDAC6/TOR1A/VCP",3]
["GO:0071305","cellular response to vitamin D","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"SFRP1/VDR/PENK",3]
["GO:1900017","positive regulation of cytokine production involved in inflammatory response","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"IL17A/IL6/TNF",3]
["GO:1902254","negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator","3/267","23/18866",0.00402552944858087,0.00874270053795748,0.00313151005386273,"SIRT1/BCL2/PRKN",3]
["GO:0048524","positive regulation of viral process","6/267","107/18866",0.00417153888944216,0.00904799899000204,0.00324086358460022,"SMARCB1/EP300/APOE/JUN/CSF1R/HLA-DRB1",6]
["GO:0050905","neuromuscular process","6/267","107/18866",0.00417153888944216,0.00904799899000204,0.00324086358460022,"SLC6A3/DRD2/MECP2/PTEN/PENK/PRKN",6]
["GO:0051963","regulation of synapse assembly","6/267","107/18866",0.00417153888944216,0.00904799899000204,0.00324086358460022,"ADNP/OXT/NTRK2/PDLIM5/BDNF/GPC6",6]
["GO:0001910","regulation of leukocyte mediated cytotoxicity","5/267","75/18866",0.00421587374832763,0.00913622292769091,0.00327246413487237,"NOS2/P2RX7/FADD/LEP/AGER",5]
["GO:0009064","glutamine family amino acid metabolic process","5/267","75/18866",0.00421587374832763,0.00913622292769091,0.00327246413487237,"GCLC/NOS2/GLUL/NOS3/MECP2",5]
["GO:0006383","transcription by RNA polymerase III","4/267","47/18866",0.00433960754783769,0.00938806780171299,0.00336267135992714,"BRCA1/TBP/AR/MTOR",4]
["GO:0022602","ovulation cycle process","4/267","47/18866",0.00433960754783769,0.00938806780171299,0.00336267135992714,"ESR1/SIRT1/NOS3/LEP",4]
["GO:0035722","interleukin-12-mediated signaling pathway","4/267","47/18866",0.00433960754783769,0.00938806780171299,0.00336267135992714,"IFNG/SOD2/IL10/SOD1",4]
["GO:0035850","epithelial cell differentiation involved in kidney development","4/267","47/18866",0.00433960754783769,0.00938806780171299,0.00336267135992714,"LIF/CTNNB1/GDNF/ADIPOQ",4]
["GO:0060071","Wnt signaling pathway, planar cell polarity pathway","6/267","108/18866",0.00436578405640472,0.00944060623370671,0.00338148987341598,"SFRP1/RAC1/DVL3/FZD2/GPC6/MED12",6]
["GO:0007187","G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","10/267","263/18866",0.0043963844844094,0.0095026613552624,0.00340371712873619,"GNAS/HTR2A/CCL2/OPRM1/CNR1/NPY/GNAL/DRD2/EDNRA/MC1R",10]
["GO:0060415","muscle tissue morphogenesis","5/267","76/18866",0.00446169814180215,0.00963549257007705,0.00345129536647325,"COL11A1/FGFR2/TGFB1/CHD7/FZD2",5]
["GO:1903524","positive regulation of blood circulation","5/267","76/18866",0.00446169814180215,0.00963549257007705,0.00345129536647325,"CD38/PTGS2/HTR2A/AKT1/ATP2A2",5]
["GO:0002719","negative regulation of cytokine production involved in immune response","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"TGFB1/IL10/TNF",3]
["GO:0014850","response to muscle activity","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"HIF1A/PPARGC1A/SRD5A1",3]
["GO:0021511","spinal cord patterning","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"PAX6/GLI2/SHH",3]
["GO:0021544","subpallium development","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"FGF8/DRD2/LRRK2",3]
["GO:0021871","forebrain regionalization","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"PAX6/FGF8/SHH",3]
["GO:0030325","adrenal gland development","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"TSPO/PDGFRB/NF1",3]
["GO:0032331","negative regulation of chondrocyte differentiation","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"GLI2/CTNNB1/PTPN11",3]
["GO:0032469","endoplasmic reticulum calcium ion homeostasis","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"BAX/BCL2/ATP2A2",3]
["GO:0044321","response to leptin","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"SIRT1/PTEN/LEP",3]
["GO:0044346","fibroblast apoptotic process","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"SFRP1/PIK3CA/TP53",3]
["GO:0051349","positive regulation of lyase activity","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"NOS2/NOS3/NF1",3]
["GO:0060444","branching involved in mammary gland duct morphogenesis","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"ESR1/VDR/AR",3]
["GO:1902993","positive regulation of amyloid precursor protein catabolic process","3/267","24/18866",0.00455297254212912,0.00977763092595729,0.003502207288773,"IFNG/AGER/TNF",3]
["GO:0043433","negative regulation of DNA-binding transcription factor activity","8/267","183/18866",0.00462364814784202,0.00992513981176923,0.0035550428579371,"HDAC4/ESR1/SIRT1/MEN1/IL10/CDKN2A/PTCH1/HDAC2",8]
["GO:0014911","positive regulation of smooth muscle cell migration","4/267","48/18866",0.00468233709853959,0.0100338665806902,0.00359398722856054,"IGF1/HDAC4/PDGFRB/BCL2",4]
["GO:0033628","regulation of cell adhesion mediated by integrin","4/267","48/18866",0.00468233709853959,0.0100338665806902,0.00359398722856054,"LIF/RET/PTPN11/DPP4",4]
["GO:0042461","photoreceptor cell development","4/267","48/18866",0.00468233709853959,0.0100338665806902,0.00359398722856054,"PAX6/VEGFA/NTRK2/PRKCI",4]
["GO:0055010","ventricular cardiac muscle tissue morphogenesis","4/267","48/18866",0.00468233709853959,0.0100338665806902,0.00359398722856054,"COL11A1/FGFR2/TGFB1/CHD7",4]
["GO:0030500","regulation of bone mineralization","5/267","77/18866",0.0047175613458812,0.010096349678519,0.00361636777884908,"P2RX7/HIF1A/GATA1/TGFB1/PTK2B",5]
["GO:0061418","regulation of transcription from RNA polymerase II promoter in response to hypoxia","5/267","77/18866",0.0047175613458812,0.010096349678519,0.00361636777884908,"CREBBP/EP300/HIF1A/VEGFA/TP53",5]
["GO:0070830","bicellular tight junction assembly","5/267","77/18866",0.0047175613458812,0.010096349678519,0.00361636777884908,"PRKACA/DLG1/SRF/PRKCI/TNF",5]
["GO:0090175","regulation of establishment of planar polarity","6/267","110/18866",0.00477419204522703,0.0102131709005221,0.00365821146657679,"SFRP1/RAC1/DVL3/FZD2/GPC6/MED12",6]
["GO:0038061","NIK/NF-kappaB signaling","8/267","184/18866",0.00477625588691502,0.0102132101256388,0.00365822551645153,"EP300/IL1B/AKT1/IL18/NR3C2/ALK/AGER/TNF",8]
["GO:0044843","cell cycle G1/S phase transition","11/267","310/18866",0.00482635252649652,0.0103159153102727,0.00369501304186985,"BAX/EP300/CCL2/MEN1/TP53/AKT1/PLK2/CDKN2A/CDK5/BCL2/PTEN",11]
["GO:0043367","CD4-positive, alpha-beta T cell differentiation","5/267","78/18866",0.00498368111270184,0.0106430794678017,0.00381219855498646,"IL2/IFNG/IL6/IL18/MTOR",5]
["GO:0051057","positive regulation of small GTPase mediated signal transduction","5/267","78/18866",0.00498368111270184,0.0106430794678017,0.00381219855498646,"IGF1/PDGFRB/KRAS/NGF/RAC1",5]
["GO:0034440","lipid oxidation","6/267","111/18866",0.00498861763453892,0.0106490670582526,0.0038143432240866,"PPARGC1A/CNR1/AKT1/LEP/ADIPOQ/MTOR",6]
["GO:0002686","negative regulation of leukocyte migration","4/267","49/18866",0.00504280597235677,0.010723479650757,0.00384099674842381,"CCL2/DUSP1/AKT1/DPP4",4]
["GO:0010171","body morphogenesis","4/267","49/18866",0.00504280597235677,0.010723479650757,0.00384099674842381,"GNAS/EP300/COL1A1/PTPN11",4]
["GO:0021517","ventral spinal cord development","4/267","49/18866",0.00504280597235677,0.010723479650757,0.00384099674842381,"PAX6/GLI2/SHH/PTCH1",4]
["GO:0042149","cellular response to glucose starvation","4/267","49/18866",0.00504280597235677,0.010723479650757,0.00384099674842381,"XBP1/ATF4/TP53/BCL2",4]
["GO:0061383","trabecula morphogenesis","4/267","49/18866",0.00504280597235677,0.010723479650757,0.00384099674842381,"SFRP1/COL1A1/SRF/CHD7",4]
["GO:0071349","cellular response to interleukin-12","4/267","49/18866",0.00504280597235677,0.010723479650757,0.00384099674842381,"IFNG/SOD2/IL10/SOD1",4]
["GO:0090151","establishment of protein localization to mitochondrial membrane","4/267","49/18866",0.00504280597235677,0.010723479650757,0.00384099674842381,"BAX/MAPK8/TP53/BCL2",4]
["GO:0120178","steroid hormone biosynthetic process","4/267","49/18866",0.00504280597235677,0.010723479650757,0.00384099674842381,"REST/TSPO/PPARGC1A/SRD5A1",4]
["GO:2000107","negative regulation of leukocyte apoptotic process","4/267","49/18866",0.00504280597235677,0.010723479650757,0.00384099674842381,"HIF1A/IL2/IDO1/FADD",4]
["GO:0007530","sex determination","3/267","25/18866",0.00512030303929346,0.010851304361287,0.00388678172806702,"SRD5A1/GNRH1/AR",3]
["GO:0010592","positive regulation of lamellipodium assembly","3/267","25/18866",0.00512030303929346,0.010851304361287,0.00388678172806702,"HDAC4/RAC1/MTOR",3]
["GO:0014829","vascular associated smooth muscle contraction","3/267","25/18866",0.00512030303929346,0.010851304361287,0.00388678172806702,"CD38/HTR2A/EDNRA",3]
["GO:0042537","benzene-containing compound metabolic process","3/267","25/18866",0.00512030303929346,0.010851304361287,0.00388678172806702,"CYP2E1/IDO1/GSTM1",3]
["GO:0048169","regulation of long-term neuronal synaptic plasticity","3/267","25/18866",0.00512030303929346,0.010851304361287,0.00388678172806702,"KRAS/DRD2/NF1",3]
["GO:0051788","response to misfolded protein","3/267","25/18866",0.00512030303929346,0.010851304361287,0.00388678172806702,"HDAC6/TOR1A/VCP",3]
["GO:0051894","positive regulation of focal adhesion assembly","3/267","25/18866",0.00512030303929346,0.010851304361287,0.00388678172806702,"SFRP1/VEGFA/RAC1",3]
["GO:1903421","regulation of synaptic vesicle recycling","3/267","25/18866",0.00512030303929346,0.010851304361287,0.00388678172806702,"TOR1A/CDK5/LRRK2",3]
["GO:0008277","regulation of G protein-coupled receptor signaling pathway","7/267","148/18866",0.00518084199910332,0.0109702901193905,0.0039294007216091,"FGF8/OPRM1/STMN1/DRD2/CXCL8/F2/KCTD16",7]
["GO:2001251","negative regulation of chromosome organization","7/267","148/18866",0.00518084199910332,0.0109702901193905,0.0039294007216091,"BRCA1/ATRX/SIRT1/SMARCB1/DUSP1/DNMT1/PAX5",7]
["GO:0045333","cellular respiration","8/267","187/18866",0.00525734324727201,0.0111243322557369,0.00398457640749619,"NOS2/HIF1A/PPARGC1A/IFNG/PIK3CA/CYP1A2/VCP/MECP2",8]
["GO:0007492","endoderm development","5/267","79/18866",0.0052602740748638,0.0111243322557369,0.00398457640749619,"COL11A1/FGF8/DUSP1/CTNNB1/MED12",5]
["GO:0120192","tight junction assembly","5/267","79/18866",0.0052602740748638,0.0111243322557369,0.00398457640749619,"PRKACA/DLG1/SRF/PRKCI/TNF",5]
["GO:0043616","keratinocyte proliferation","4/267","50/18866",0.00542141693556465,0.0114408853589494,0.00409796119300812,"FGFR2/VDR/CDH13/PTCH1",4]
["GO:0045104","intermediate filament cytoskeleton organization","4/267","50/18866",0.00542141693556465,0.0114408853589494,0.00409796119300812,"GFAP/TOR1A/SOD1/SHH",4]
["GO:0070671","response to interleukin-12","4/267","50/18866",0.00542141693556465,0.0114408853589494,0.00409796119300812,"IFNG/SOD2/IL10/SOD1",4]
["GO:0097300","programmed necrotic cell death","4/267","50/18866",0.00542141693556465,0.0114408853589494,0.00409796119300812,"BAX/TP53/FADD/TNF",4]
["GO:2000725","regulation of cardiac muscle cell differentiation","4/267","50/18866",0.00542141693556465,0.0114408853589494,0.00409796119300812,"IGF1/TGFB1/DLL1/MTOR",4]
["GO:0007009","plasma membrane organization","6/267","113/18866",0.0054385691863083,0.0114722331842997,0.00410918953484882,"P2RX7/SOD1/AKT1/AR/PTEN/ATP2A2",6]
["GO:0070828","heterochromatin organization","5/267","80/18866",0.00554755562437494,0.0116971897096723,0.0041897657387149,"SIRT1/DNMT1/CDKN2A/MTHFR/HDAC2",5]
["GO:0006644","phospholipid metabolic process","14/267","455/18866",0.00556826289045278,0.0117358955728285,0.00420362962426041,"PON1/FGFR3/HTR2A/TGFB1/GNB3/PDGFRB/PTK2B/PIK3CA/PIK3R1/INPPL1/MECP2/PTEN/LPL/CSF1R",14]
["GO:0003279","cardiac septum development","6/267","114/18866",0.00567435791061289,0.0119544595137933,0.00428191609599436,"FGFR2/FGF8/TP53/NOS3/CHD7/FZD2",6]
["GO:0002068","glandular epithelial cell development","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"PAX6/GSK3B/DLL1",3]
["GO:0006700","C21-steroid hormone biosynthetic process","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"REST/TSPO/PPARGC1A",3]
["GO:0035902","response to immobilization stress","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"PTK2B/CYP1A2/FOS",3]
["GO:0043501","skeletal muscle adaptation","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"PPARGC1A/ATP2A2/MTOR",3]
["GO:0043567","regulation of insulin-like growth factor receptor signaling pathway","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"IGF1/POU1F1/AR",3]
["GO:0060343","trabecula formation","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"SFRP1/COL1A1/SRF",3]
["GO:0072012","glomerulus vasculature development","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"NOTCH3/PDGFRB/IL6R",3]
["GO:0097066","response to thyroid hormone","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"GCLC/GATA1/PPARGC1A",3]
["GO:1900739","regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"MAPK8/TP53/BCL2",3]
["GO:1900740","positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"MAPK8/TP53/BCL2",3]
["GO:1903020","positive regulation of glycoprotein metabolic process","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"IGF1/CTNNB1/PAWR",3]
["GO:1905523","positive regulation of macrophage migration","3/267","26/18866",0.00572832593604163,0.0120073599490579,0.00430086427386748,"MAPK1/MAPK3/CSF1R",3]
["GO:0035567","non-canonical Wnt signaling pathway","7/267","151/18866",0.00577121360508302,0.0120921819262188,0.00433124629062705,"SFRP1/RAC1/DVL3/CTNNB1/FZD2/GPC6/MED12",7]
["GO:0006575","cellular modified amino acid metabolic process","8/267","190/18866",0.00577463653905913,0.0120942786239607,0.00433199729771347,"GCLC/TG/FOLH1/TPO/GSTM1/SOD1/MTHFR/GPX1",8]
["GO:0031113","regulation of microtubule polymerization","4/267","51/18866",0.00581856474550886,0.0121607759624637,0.0043558156914893,"STMN1/RAC1/MECP2/MAPT",4]
["GO:0032206","positive regulation of telomere maintenance","4/267","51/18866",0.00581856474550886,0.0121607759624637,0.0043558156914893,"ATRX/MAPK1/MAPK3/CTNNB1",4]
["GO:0045103","intermediate filament-based process","4/267","51/18866",0.00581856474550886,0.0121607759624637,0.0043558156914893,"GFAP/TOR1A/SOD1/SHH",4]
["GO:0071354","cellular response to interleukin-6","4/267","51/18866",0.00581856474550886,0.0121607759624637,0.0043558156914893,"PPARGC1A/IL6/IL6R/PTPN11",4]
["GO:1903573","negative regulation of response to endoplasmic reticulum stress","4/267","51/18866",0.00581856474550886,0.0121607759624637,0.0043558156914893,"XBP1/BCL2L1/PRKN/LRRK2",4]
["GO:0033238","regulation of cellular amine metabolic process","5/267","81/18866",0.00584573979417353,0.0122124597457358,0.00437432808205278,"COMT/SLC6A3/NQO1/PRKN/INS",5]
["GO:0048640","negative regulation of developmental growth","6/267","115/18866",0.00591753025985088,0.0123572683343519,0.00442619644345534,"FGFR3/SFRP1/CDK5/PTEN/PTCH1/DCC",6]
["GO:0120193","tight junction organization","5/267","82/18866",0.00615503914226596,0.0128478722564105,0.00460192373821064,"PRKACA/DLG1/SRF/PRKCI/TNF",5]
["GO:0051339","regulation of lyase activity","4/267","52/18866",0.00623463591509246,0.0129922942921772,0.00465365364192166,"NOS2/DRD2/NOS3/NF1",4]
["GO:0051496","positive regulation of stress fiber assembly","4/267","52/18866",0.00623463591509246,0.0129922942921772,0.00465365364192166,"TAC1/SFRP1/RAC1/MTOR",4]
["GO:0055078","sodium ion homeostasis","4/267","52/18866",0.00623463591509246,0.0129922942921772,0.00465365364192166,"TAC1/COMT/OXT/DRD2",4]
["GO:0090329","regulation of DNA-dependent DNA replication","4/267","52/18866",0.00623463591509246,0.0129922942921772,0.00465365364192166,"FGFR1/ATRX/TIMELESS/BRCA2",4]
["GO:0001702","gastrulation with mouth forming second","3/267","27/18866",0.00637778733594398,0.0132353666535197,0.0047407186786406,"SRF/OTX2/CTNNB1",3]
["GO:0002021","response to dietary excess","3/267","27/18866",0.00637778733594398,0.0132353666535197,0.0047407186786406,"PPARGC1A/APOE/LEP",3]
["GO:0007214","gamma-aminobutyric acid signaling pathway","3/267","27/18866",0.00637778733594398,0.0132353666535197,0.0047407186786406,"GABRA3/ATF4/BDNF",3]
["GO:0008053","mitochondrial fusion","3/267","27/18866",0.00637778733594398,0.0132353666535197,0.0047407186786406,"BAX/MFN2/PRKN",3]
["GO:0009065","glutamine family amino acid catabolic process","3/267","27/18866",0.00637778733594398,0.0132353666535197,0.0047407186786406,"NOS2/GLUL/NOS3",3]
["GO:0031954","positive regulation of protein autophosphorylation","3/267","27/18866",0.00637778733594398,0.0132353666535197,0.0047407186786406,"VEGFA/ACE/INS",3]
["GO:0034698","response to gonadotropin","3/267","27/18866",0.00637778733594398,0.0132353666535197,0.0047407186786406,"GCLC/PPARGC1A/SRD5A1",3]
["GO:0042481","regulation of odontogenesis","3/267","27/18866",0.00637778733594398,0.0132353666535197,0.0047407186786406,"NGFR/FGF8/SHH",3]
["GO:0051953","negative regulation of amine transport","3/267","27/18866",0.00637778733594398,0.0132353666535197,0.0047407186786406,"CNR1/DRD2/LEP",3]
["GO:1901623","regulation of lymphocyte chemotaxis","3/267","27/18866",0.00637778733594398,0.0132353666535197,0.0047407186786406,"CCL2/PTK2B/ADAM10",3]
["GO:0002262","myeloid cell homeostasis","7/267","154/18866",0.006410538815635,0.0132978065253284,0.00476308374598818,"BAX/HIF1A/GATA1/SRF/VEGFA/IL6/SOD1",7]
["GO:0043666","regulation of phosphoprotein phosphatase activity","6/267","117/18866",0.00642654972804329,0.0133199513458365,0.00477101570336918,"GSK3B/PDGFRB/PPP1R1B/DRD2/MTOR/TNF",6]
["GO:0072676","lymphocyte migration","6/267","117/18866",0.00642654972804329,0.0133199513458365,0.00477101570336918,"CCL2/PTK2B/ADAM10/AKT1/RET/FADD",6]
["GO:0110053","regulation of actin filament organization","10/267","278/18866",0.00643804960576733,0.0133382496604134,0.00477756989744429,"TAC1/DLG1/SFRP1/STMN1/PTK2B/RAC1/PIK3R1/PRKCE/PRKN/MTOR",10]
["GO:0055117","regulation of cardiac muscle contraction","5/267","83/18866",0.0064756646385149,0.0134106153214869,0.00480349024027454,"HDAC4/PRKACA/DLG1/ATP2A2/DMD",5]
["GO:0051056","regulation of small GTPase mediated signal transduction","11/267","323/18866",0.00651430576392982,0.0134850450577536,0.00483014990526174,"IGF1/TSC2/PDGFRB/MFN2/STMN1/APOE/KRAS/NGF/RAC1/SQSTM1/NF1",11]
["GO:0043124","negative regulation of I-kappaB kinase/NF-kappaB signaling","4/267","53/18866",0.00667000849465344,0.013778797026812,0.00493536765124935,"ESR1/SIRT1/ADIPOQ/TLE1",4]
["GO:0043331","response to dsRNA","4/267","53/18866",0.00667000849465344,0.013778797026812,0.00493536765124935,"P2RX7/MAPK1/MAPK3/IFNA1",4]
["GO:0043392","negative regulation of DNA binding","4/267","53/18866",0.00667000849465344,0.013778797026812,0.00493536765124935,"GATA1/PER2/JUN/HDAC2",4]
["GO:0045661","regulation of myoblast differentiation","4/267","53/18866",0.00667000849465344,0.013778797026812,0.00493536765124935,"TGFB1/IL18/DLL1/TNF",4]
["GO:0045744","negative regulation of G protein-coupled receptor signaling pathway","4/267","53/18866",0.00667000849465344,0.013778797026812,0.00493536765124935,"OPRM1/STMN1/DRD2/CXCL8",4]
["GO:0007219","Notch signaling pathway","8/267","195/18866",0.00672186759436998,0.0138801839944952,0.00497168301024535,"CREBBP/NOTCH3/EP300/ADAM10/AKT1/PRKCI/NOS3/DLL1",8]
["GO:0050851","antigen receptor-mediated signaling pathway","11/267","325/18866",0.00681067069522397,0.0140577423651316,0.00503528187427842,"CD38/BAX/MAPK1/PIK3CA/PIK3R1/BCL2/PAWR/HLA-DQB1/PAX5/HLA-DRB1/HLA-DQA1",11]
["GO:0006865","amino acid transport","7/267","156/18866",0.00686512885824598,0.0141642927228191,0.005073446685585,"P2RX7/PER2/NTRK2/LEP/BDNF/CCK/NF1",7]
["GO:1901222","regulation of NIK/NF-kappaB signaling","6/267","119/18866",0.0069666727682656,0.0143678633341388,0.00514636276148754,"EP300/IL1B/IL18/NR3C2/AGER/TNF",6]
["GO:0010894","negative regulation of steroid biosynthetic process","3/267","28/18866",0.00706937633448112,0.0145256773819194,0.00520288949200062,"REST/APOE/SOD1",3]
["GO:0021846","cell proliferation in forebrain","3/267","28/18866",0.00706937633448112,0.0145256773819194,0.00520288949200062,"FGFR2/FGFR1/FGF8",3]
["GO:0031645","negative regulation of nervous system process","3/267","28/18866",0.00706937633448112,0.0145256773819194,0.00520288949200062,"IL10/PTEN/LRRK2",3]
["GO:0045686","negative regulation of glial cell differentiation","3/267","28/18866",0.00706937633448112,0.0145256773819194,0.00520288949200062,"CTNNB1/F2/NF1",3]
["GO:0045745","positive regulation of G protein-coupled receptor signaling pathway","3/267","28/18866",0.00706937633448112,0.0145256773819194,0.00520288949200062,"FGF8/DRD2/F2",3]
["GO:0051450","myoblast proliferation","3/267","28/18866",0.00706937633448112,0.0145256773819194,0.00520288949200062,"IGF1/GPX1/MALAT1",3]
["GO:0061437","renal system vasculature development","3/267","28/18866",0.00706937633448112,0.0145256773819194,0.00520288949200062,"NOTCH3/PDGFRB/IL6R",3]
["GO:0061440","kidney vasculature development","3/267","28/18866",0.00706937633448112,0.0145256773819194,0.00520288949200062,"NOTCH3/PDGFRB/IL6R",3]
["GO:1900101","regulation of endoplasmic reticulum unfolded protein response","3/267","28/18866",0.00706937633448112,0.0145256773819194,0.00520288949200062,"BAX/XBP1/PIK3R1",3]
["GO:0006749","glutathione metabolic process","4/267","54/18866",0.00712505187061197,0.0146280361800845,0.00523955294674936,"GCLC/GSTM1/SOD1/GPX1",4]
["GO:0010043","response to zinc ion","4/267","54/18866",0.00712505187061197,0.0146280361800845,0.00523955294674936,"P2RX7/TSPO/CREB1/PTEN",4]
["GO:0031110","regulation of microtubule polymerization or depolymerization","5/267","85/18866",0.00715172935373794,0.0146586964955721,0.00525053503240893,"HDAC6/STMN1/RAC1/MECP2/MAPT",5]
["GO:0035418","protein localization to synapse","5/267","85/18866",0.00715172935373794,0.0146586964955721,0.00525053503240893,"DLG1/ADAM10/CDK5/GPC6/MAPT",5]
["GO:0043297","apical junction assembly","5/267","85/18866",0.00715172935373794,0.0146586964955721,0.00525053503240893,"PRKACA/DLG1/SRF/PRKCI/TNF",5]
["GO:0070509","calcium ion import","5/267","85/18866",0.00715172935373794,0.0146586964955721,0.00525053503240893,"CCL2/PDGFRB/CDK5/CTNNB1/ATP2A2",5]
["GO:0032886","regulation of microtubule-based process","9/267","240/18866",0.00735885262622523,0.0150770419215193,0.0054003803692878,"BRCA1/GSK3B/HDAC6/STMN1/RAC1/PLK2/CTNNB1/MECP2/MAPT",9]
["GO:0038093","Fc receptor signaling pathway","9/267","241/18866",0.00755267316369219,0.0154678002897109,0.0055403444173883,"MAPK1/MAPK3/MAPK8/PIK3CA/RAC1/PIK3R1/FOS/PRKCE/JUN",9]
["GO:0019933","cAMP-mediated signaling","8/267","199/18866",0.00756079751416406,0.0154780901960726,0.00554403011439751,"GNAS/PRKAR1A/OPRM1/CNR1/PDE11A/GNAL/DRD2/MC1R",8]
["GO:0003229","ventricular cardiac muscle tissue development","4/267","55/18866",0.00760012658028346,0.0155331281274479,0.00556374391274817,"COL11A1/FGFR2/TGFB1/CHD7",4]
["GO:0008347","glial cell migration","4/267","55/18866",0.00760012658028346,0.0155331281274479,0.00556374391274817,"TSPO/CCL2/CDK5/CTNNB1",4]
["GO:0014888","striated muscle adaptation","4/267","55/18866",0.00760012658028346,0.0155331281274479,0.00556374391274817,"HDAC4/PPARGC1A/ATP2A2/MTOR",4]
["GO:0070741","response to interleukin-6","4/267","55/18866",0.00760012658028346,0.0155331281274479,0.00556374391274817,"PPARGC1A/IL6/IL6R/PTPN11",4]
["GO:0140014","mitotic nuclear division","10/267","286/18866",0.00779345876213178,0.0158907048108579,0.00569182275683799,"IGF1/ATRX/FGF8/SMC3/PDGFRB/IL1A/DUSP1/IL1B/POGZ/INS",10]
["GO:0001782","B cell homeostasis","3/267","29/18866",0.00780372685684427,0.0158907048108579,0.00569182275683799,"BAX/HIF1A/BCL2",3]
["GO:0006515","protein quality control for misfolded or incompletely synthesized proteins","3/267","29/18866",0.00780372685684427,0.0158907048108579,0.00569182275683799,"HDAC6/TOR1A/VCP",3]
["GO:0042634","regulation of hair cycle","3/267","29/18866",0.00780372685684427,0.0158907048108579,0.00569182275683799,"NGFR/CTNNB1/TNF",3]
["GO:0045822","negative regulation of heart contraction","3/267","29/18866",0.00780372685684427,0.0158907048108579,0.00569182275683799,"TAC1/IL2/ATP2A2",3]
["GO:0048679","regulation of axon regeneration","3/267","29/18866",0.00780372685684427,0.0158907048108579,0.00569182275683799,"GRN/MAP2K1/PTEN",3]
["GO:0090344","negative regulation of cell aging","3/267","29/18866",0.00780372685684427,0.0158907048108579,0.00569182275683799,"SIRT1/PLK2/PTEN",3]
["GO:0150117","positive regulation of cell-substrate junction organization","3/267","29/18866",0.00780372685684427,0.0158907048108579,0.00569182275683799,"SFRP1/VEGFA/RAC1",3]
["GO:2000727","positive regulation of cardiac muscle cell differentiation","3/267","29/18866",0.00780372685684427,0.0158907048108579,0.00569182275683799,"IGF1/TGFB1/MTOR",3]
["GO:0000082","G1/S transition of mitotic cell cycle","10/267","287/18866",0.00797727591485241,0.016237480082698,0.00581603269008271,"BAX/EP300/CCL2/TP53/AKT1/PLK2/CDKN2A/CDK5/BCL2/PTEN",10]
["GO:0002712","regulation of B cell mediated immunity","4/267","56/18866",0.00809558414227079,0.0164514658617656,0.00589267932982802,"TGFB1/IL2/IL10/TNF",4]
["GO:0002889","regulation of immunoglobulin mediated immune response","4/267","56/18866",0.00809558414227079,0.0164514658617656,0.00589267932982802,"TGFB1/IL2/IL10/TNF",4]
["GO:0006977","DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","4/267","56/18866",0.00809558414227079,0.0164514658617656,0.00589267932982802,"BAX/EP300/TP53/PLK2",4]
["GO:0060563","neuroepithelial cell differentiation","4/267","56/18866",0.00809558414227079,0.0164514658617656,0.00589267932982802,"FGFR1/FGF8/SOD1/DLL1",4]
["GO:0031570","DNA integrity checkpoint","7/267","161/18866",0.00810606568273793,0.0164660642611516,0.0058979082672998,"BRCA1/BAX/EP300/TIMELESS/TP53/PLK2/PTPN11",7]
["GO:0000280","nuclear division","13/267","428/18866",0.0082322497082994,0.01667915720058,0.00597423510468033,"IGF1/ATRX/FGF8/SMC3/PRKAR1A/PDGFRB/IL1A/DUSP1/IL1B/LIF/BRCA2/POGZ/INS",13]
["GO:0003149","membranous septum morphogenesis","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"FGFR2/FZD2",2]
["GO:0007440","foregut morphogenesis","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"SHH/CTNNB1",2]
["GO:0010269","response to selenium ion","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"APOB/GPX1",2]
["GO:0010749","regulation of nitric oxide mediated signal transduction","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"VEGFA/INS",2]
["GO:0014049","positive regulation of glutamate secretion","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"P2RX7/CCK",2]
["GO:0014051","gamma-aminobutyric acid secretion","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"P2RX7/NF1",2]
["GO:0021936","regulation of cerebellar granule cell precursor proliferation","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"GLI2/SHH",2]
["GO:0032070","regulation of deoxyribonuclease activity","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"SIRT1/AKT1",2]
["GO:0032817","regulation of natural killer cell proliferation","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"IL18/LEP",2]
["GO:0034447","very-low-density lipoprotein particle clearance","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"APOB/APOE",2]
["GO:0035907","dorsal aorta development","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"NGFR/SRF",2]
["GO:0042756","drinking behavior","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"OXT/DRD2",2]
["GO:0043084","penile erection","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"OXT/CNR1",2]
["GO:0043587","tongue morphogenesis","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"CTNNB1/HDAC2",2]
["GO:0048570","notochord morphogenesis","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"GLI2/KDM6A",2]
["GO:0051409","response to nitrosative stress","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"GCLC/DUSP6",2]
["GO:0051541","elastin metabolic process","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"HIF1A/LEP",2]
["GO:0051967","negative regulation of synaptic transmission, glutamatergic","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"HTR2A/DRD2",2]
["GO:0060068","vagina development","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"BAX/ESR1",2]
["GO:0060346","bone trabecula formation","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"SFRP1/COL1A1",2]
["GO:0060502","epithelial cell proliferation involved in lung morphogenesis","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"FGFR2/MAP2K1",2]
["GO:0070091","glucagon secretion","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"IL6/LEP",2]
["GO:0070092","regulation of glucagon secretion","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"IL6/LEP",2]
["GO:0070341","fat cell proliferation","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"PER2/FTO",2]
["GO:0070344","regulation of fat cell proliferation","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"PER2/FTO",2]
["GO:0090009","primitive streak formation","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"SRF/OTX2",2]
["GO:0090037","positive regulation of protein kinase C signaling","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"VEGFA/MC1R",2]
["GO:0090043","regulation of tubulin deacetylation","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"EP300/MAPT",2]
["GO:1901725","regulation of histone deacetylase activity","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"VEGFA/LRRK2",2]
["GO:1901838","positive regulation of transcription of nucleolar large rRNA by RNA polymerase I","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"SMARCB1/MTOR",2]
["GO:1990416","cellular response to brain-derived neurotrophic factor stimulus","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"NTRK2/MAPT",2]
["GO:2000109","regulation of macrophage apoptotic process","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"SIRT1/CDKN2A",2]
["GO:2000169","regulation of peptidyl-cysteine S-nitrosylation","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"ACE/DMD",2]
["GO:2000659","regulation of interleukin-1-mediated signaling pathway","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"VRK2/IL6",2]
["GO:2001054","negative regulation of mesenchymal cell apoptotic process","2/267","10/18866",0.00833122732991119,0.01667915720058,0.00597423510468033,"HIF1A/SHH",2]
["GO:0019827","stem cell population maintenance","7/267","162/18866",0.00837286708032872,0.0167558017363051,0.0060016880790965,"REST/SFRP1/SMC3/LIF/CTNNB1/MED12/DLL1",7]
["GO:0001736","establishment of planar polarity","6/267","124/18866",0.00845986543081923,0.0169095708951483,0.00605676598835357,"SFRP1/RAC1/DVL3/FZD2/GPC6/MED12",6]
["GO:0002698","negative regulation of immune effector process","6/267","124/18866",0.00845986543081923,0.0169095708951483,0.00605676598835357,"GRN/TGFB1/IL2/IL10/TNF/INS",6]
["GO:0007164","establishment of tissue polarity","6/267","124/18866",0.00845986543081923,0.0169095708951483,0.00605676598835357,"SFRP1/RAC1/DVL3/FZD2/GPC6/MED12",6]
["GO:0001516","prostaglandin biosynthetic process","3/267","30/18866",0.00858141945023057,0.0170909562485047,0.00612173562275806,"PTGS2/SIRT1/IL1B",3]
["GO:0007271","synaptic transmission, cholinergic","3/267","30/18866",0.00858141945023057,0.0170909562485047,0.00612173562275806,"TAC1/APOE/NQO1",3]
["GO:0030511","positive regulation of transforming growth factor beta receptor signaling pathway","3/267","30/18866",0.00858141945023057,0.0170909562485047,0.00612173562275806,"CREBBP/EP300/MEN1",3]
["GO:0031116","positive regulation of microtubule polymerization","3/267","30/18866",0.00858141945023057,0.0170909562485047,0.00612173562275806,"RAC1/MECP2/MAPT",3]
["GO:0033137","negative regulation of peptidyl-serine phosphorylation","3/267","30/18866",0.00858141945023057,0.0170909562485047,0.00612173562275806,"BAX/PTEN/DMD",3]
["GO:0042133","neurotransmitter metabolic process","3/267","30/18866",0.00858141945023057,0.0170909562485047,0.00612173562275806,"COMT/SLC6A3/MAOA",3]
["GO:0045939","negative regulation of steroid metabolic process","3/267","30/18866",0.00858141945023057,0.0170909562485047,0.00612173562275806,"REST/APOE/SOD1",3]
["GO:0046457","prostanoid biosynthetic process","3/267","30/18866",0.00858141945023057,0.0170909562485047,0.00612173562275806,"PTGS2/SIRT1/IL1B",3]
["GO:1903846","positive regulation of cellular response to transforming growth factor beta stimulus","3/267","30/18866",0.00858141945023057,0.0170909562485047,0.00612173562275806,"CREBBP/EP300/MEN1",3]
["GO:0019748","secondary metabolic process","4/267","57/18866",0.00861176690186478,0.0171104465344253,0.0061287167638881,"CYP2D6/CYP1A2/BCL2/MC1R",4]
["GO:0021515","cell differentiation in spinal cord","4/267","57/18866",0.00861176690186478,0.0171104465344253,0.0061287167638881,"PAX6/GLI2/SHH/PTCH1",4]
["GO:0061178","regulation of insulin secretion involved in cellular response to glucose stimulus","4/267","57/18866",0.00861176690186478,0.0171104465344253,0.0061287167638881,"HIF1A/RAC1/PRKCE/HLA-DRB1",4]
["GO:0072431","signal transduction involved in mitotic G1 DNA damage checkpoint","4/267","57/18866",0.00861176690186478,0.0171104465344253,0.0061287167638881,"BAX/EP300/TP53/PLK2",4]
["GO:0098900","regulation of action potential","4/267","57/18866",0.00861176690186478,0.0171104465344253,0.0061287167638881,"TAC1/DLG1/CNR1/ATP2A2",4]
["GO:1902400","intracellular signal transduction involved in G1 DNA damage checkpoint","4/267","57/18866",0.00861176690186478,0.0171104465344253,0.0061287167638881,"BAX/EP300/TP53/PLK2",4]
["GO:0043506","regulation of JUN kinase activity","5/267","89/18866",0.00864885365092534,0.0171772976448171,0.00615266187368511,"SFRP1/PTK2B/DVL3/AGER/TNF",5]
["GO:0006029","proteoglycan metabolic process","5/267","90/18866",0.0090545134115771,0.0179686746677283,0.00643612178322713,"IGF1/COL11A1/IDUA/COL2A1/CTNNB1",5]
["GO:0032465","regulation of cytokinesis","5/267","90/18866",0.0090545134115771,0.0179686746677283,0.00643612178322713,"BRCA2/PLK2/DRD2/PRKCE/BCL2L1",5]
["GO:0002011","morphogenesis of an epithelial sheet","4/267","58/18866",0.00914900789089832,0.0181417777598313,0.00649812483033161,"SRF/TOR1A/PTEN/MTOR",4]
["GO:0035306","positive regulation of dephosphorylation","4/267","58/18866",0.00914900789089832,0.0181417777598313,0.00649812483033161,"TGFB1/IFNG/PDGFRB/MTOR",4]
["GO:0010498","proteasomal protein catabolic process","14/267","483/18866",0.00918681593416209,0.018209516458623,0.00652238786157472,"GCLC/PRKACA/GSK3B/SIRT1/APOE/TOR1A/AKT1/PLK2/SHH/VCP/CTNNB1/PRKN/LRRK2/GPX1",14]
["GO:0002828","regulation of type 2 immune response","3/267","31/18866",0.00940298303161557,0.0185716353943262,0.00665209367534762,"IDO1/IL6/IL18",3]
["GO:0006356","regulation of transcription by RNA polymerase I","3/267","31/18866",0.00940298303161557,0.0185716353943262,0.00665209367534762,"SMARCB1/ATF4/MTOR",3]
["GO:0008045","motor neuron axon guidance","3/267","31/18866",0.00940298303161557,0.0185716353943262,0.00665209367534762,"FGF8/RAC1/CDK5",3]
["GO:0034377","plasma lipoprotein particle assembly","3/267","31/18866",0.00940298303161557,0.0185716353943262,0.00665209367534762,"PRKACA/APOB/APOE",3]
["GO:0045987","positive regulation of smooth muscle contraction","3/267","31/18866",0.00940298303161557,0.0185716353943262,0.00665209367534762,"PTGS2/OXT/SRF",3]
["GO:0060325","face morphogenesis","3/267","31/18866",0.00940298303161557,0.0185716353943262,0.00665209367534762,"EP300/COL1A1/PTPN11",3]
["GO:0098868","bone growth","3/267","31/18866",0.00940298303161557,0.0185716353943262,0.00665209367534762,"FGFR2/FGFR3/LEP",3]
["GO:1902230","negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage","3/267","31/18866",0.00940298303161557,0.0185716353943262,0.00665209367534762,"SIRT1/BCL2L1/BCL2",3]
["GO:1903792","negative regulation of anion transport","3/267","31/18866",0.00940298303161557,0.0185716353943262,0.00665209367534762,"AKT1/LEP/MTOR",3]
["GO:1901343","negative regulation of vasculature development","8/267","207/18866",0.00947246857190562,0.0187014770974792,0.00669860111284579,"NGFR/DNMT1/PLK2/CTNNB1/MECP2/PRL/NF1/TNF",8]
["GO:1901987","regulation of cell cycle phase transition","14/267","486/18866",0.00966476003066412,0.019073575823362,0.00683188154445531,"BRCA1/PRKACA/BAX/EP300/CCL2/DUSP1/MEN1/TP53/AKT1/PLK2/CDKN2A/MECP2/BCL2/PTEN",14]
["GO:0006636","unsaturated fatty acid biosynthetic process","4/267","59/18866",0.00970763070151502,0.0190977935747299,0.00684055599596617,"PTGS2/SIRT1/IL1B/GSTM1",4]
["GO:0032387","negative regulation of intracellular transport","4/267","59/18866",0.00970763070151502,0.0190977935747299,0.00684055599596617,"CDK5/ADIPOQ/LRRK2/NF1",4]
["GO:0043030","regulation of macrophage activation","4/267","59/18866",0.00970763070151502,0.0190977935747299,0.00684055599596617,"GRN/IL6/IL10/LRRK2",4]
["GO:0045815","positive regulation of gene expression, epigenetic","4/267","59/18866",0.00970763070151502,0.0190977935747299,0.00684055599596617,"ARID1B/EP300/TBP/CTNNB1",4]
["GO:0060113","inner ear receptor cell differentiation","4/267","59/18866",0.00970763070151502,0.0190977935747299,0.00684055599596617,"FGFR1/SOD1/FZD2/DLL1",4]
["GO:0072413","signal transduction involved in mitotic cell cycle checkpoint","4/267","59/18866",0.00970763070151502,0.0190977935747299,0.00684055599596617,"BAX/EP300/TP53/PLK2",4]
["GO:1902402","signal transduction involved in mitotic DNA damage checkpoint","4/267","59/18866",0.00970763070151502,0.0190977935747299,0.00684055599596617,"BAX/EP300/TP53/PLK2",4]
["GO:1902403","signal transduction involved in mitotic DNA integrity checkpoint","4/267","59/18866",0.00970763070151502,0.0190977935747299,0.00684055599596617,"BAX/EP300/TP53/PLK2",4]
["GO:0035303","regulation of dephosphorylation","8/267","209/18866",0.0100020949144783,0.0194553931840576,0.00696864305179122,"GSK3B/TGFB1/IFNG/PDGFRB/PPP1R1B/DRD2/MTOR/TNF",8]
["GO:0001787","natural killer cell proliferation","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"IL18/LEP",2]
["GO:0005984","disaccharide metabolic process","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"IDUA/BRAF",2]
["GO:0006527","arginine catabolic process","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"NOS2/NOS3",2]
["GO:0006707","cholesterol catabolic process","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"APOE/CYP27A1",2]
["GO:0007614","short-term memory","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"COMT/ADNP",2]
["GO:0010739","positive regulation of protein kinase A signaling","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"ADIPOQ/MC1R",2]
["GO:0010918","positive regulation of mitochondrial membrane potential","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"AKT1/VCP",2]
["GO:0014889","muscle atrophy","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"PPARGC1A/MTOR",2]
["GO:0016127","sterol catabolic process","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"APOE/CYP27A1",2]
["GO:0021521","ventral spinal cord interneuron specification","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"PAX6/GLI2",2]
["GO:0031284","positive regulation of guanylate cyclase activity","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"NOS2/NOS3",2]
["GO:0033148","positive regulation of intracellular estrogen receptor signaling pathway","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"KMT2D/AR",2]
["GO:0033197","response to vitamin E","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"COL1A1/LEP",2]
["GO:0033210","leptin-mediated signaling pathway","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"SIRT1/LEP",2]
["GO:0034115","negative regulation of heterotypic cell-cell adhesion","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"IL10/ADIPOQ",2]
["GO:0034372","very-low-density lipoprotein particle remodeling","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"APOE/LPL",2]
["GO:0034378","chylomicron assembly","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"APOB/APOE",2]
["GO:0035865","cellular response to potassium ion","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"PPARGC1A/SOD1",2]
["GO:0042135","neurotransmitter catabolic process","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"COMT/MAOA",2]
["GO:0042447","hormone catabolic process","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"SRD5A1/ACE",2]
["GO:0042789","mRNA transcription by RNA polymerase II","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"SRF/ATF4",2]
["GO:0043471","regulation of cellular carbohydrate catabolic process","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"TP53/INS",2]
["GO:0043589","skin morphogenesis","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"COL1A1/SRF",2]
["GO:0043619","regulation of transcription from RNA polymerase II promoter in response to oxidative stress","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"HIF1A/ATF4",2]
["GO:0045657","positive regulation of monocyte differentiation","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"JUN/HLA-DRB1",2]
["GO:0045835","negative regulation of meiotic nuclear division","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"PRKAR1A/LIF",2]
["GO:0045945","positive regulation of transcription by RNA polymerase III","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"AR/MTOR",2]
["GO:0048642","negative regulation of skeletal muscle tissue development","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"TGFB1/S100B",2]
["GO:0048672","positive regulation of collateral sprouting","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"NGF/BDNF",2]
["GO:0051712","positive regulation of killing of cells of other organism","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"NOS2/IFNG",2]
["GO:0051974","negative regulation of telomerase activity","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"MEN1/TP53",2]
["GO:0060272","embryonic skeletal joint morphogenesis","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"COL2A1/CTNNB1",2]
["GO:0060379","cardiac muscle cell myoblast differentiation","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"REST/SRF",2]
["GO:0060573","cell fate specification involved in pattern specification","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"PAX6/GLI2",2]
["GO:0060947","cardiac vascular smooth muscle cell differentiation","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"SRF/VEGFA",2]
["GO:0061307","cardiac neural crest cell differentiation involved in heart development","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"MAPK1/MAPK3",2]
["GO:0061308","cardiac neural crest cell development involved in heart development","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"MAPK1/MAPK3",2]
["GO:0070587","regulation of cell-cell adhesion involved in gastrulation","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"IL10/ADIPOQ",2]
["GO:0070673","response to interleukin-18","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"AKT1/IL18",2]
["GO:0071372","cellular response to follicle-stimulating hormone stimulus","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"GCLC/PPARGC1A",2]
["GO:0071838","cell proliferation in bone marrow","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"FGFR2/ACE",2]
["GO:0072110","glomerular mesangial cell proliferation","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"PDGFRB/IL6R",2]
["GO:0072205","metanephric collecting duct development","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"SHH/PTCH1",2]
["GO:0090269","fibroblast growth factor production","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"PTGS2/FGFR1",2]
["GO:0090270","regulation of fibroblast growth factor production","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"PTGS2/FGFR1",2]
["GO:0098917","retrograde trans-synaptic signaling","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"CNR1/BDNF",2]
["GO:0150104","transport across blood-brain barrier","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"ABCB1/APOE",2]
["GO:1905168","positive regulation of double-strand break repair via homologous recombination","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"FUS/TIMELESS",2]
["GO:1905245","regulation of aspartic-type peptidase activity","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"GRN/AGER",2]
["GO:2000480","negative regulation of cAMP-dependent protein kinase activity","2/267","11/18866",0.0100881259670589,0.0194553931840576,0.00696864305179122,"SIRT1/PRKAR1A",2]
["GO:0002576","platelet degranulation","6/267","129/18866",0.0101699647474775,0.0196056501869325,0.007022462957108,"IGF1/TGFB1/VEGFA/SOD1/ALB/SERPINA3",6]
["GO:0003016","respiratory system process","3/267","32/18866",0.0102688965919662,0.0197416338282202,0.00707117034883492,"FTO/KDM6A/MECP2",3]
["GO:0010165","response to X-ray","3/267","32/18866",0.0102688965919662,0.0197416338282202,0.00707117034883492,"SFRP1/BRCA2/TP53",3]
["GO:0010880","regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum","3/267","32/18866",0.0102688965919662,0.0197416338282202,0.00707117034883492,"PRKACA/CHD7/DMD",3]
["GO:0042744","hydrogen peroxide catabolic process","3/267","32/18866",0.0102688965919662,0.0197416338282202,0.00707117034883492,"TPO/GPX1/HP",3]
["GO:0050869","negative regulation of B cell activation","3/267","32/18866",0.0102688965919662,0.0197416338282202,0.00707117034883492,"SFRP1/IL10/PAWR",3]
["GO:0070570","regulation of neuron projection regeneration","3/267","32/18866",0.0102688965919662,0.0197416338282202,0.00707117034883492,"GRN/MAP2K1/PTEN",3]
["GO:0097421","liver regeneration","3/267","32/18866",0.0102688965919662,0.0197416338282202,0.00707117034883492,"IL6/IL10/PTCH1",3]
["GO:0002377","immunoglobulin production","8/267","210/18866",0.0102750173483384,0.0197416338282202,0.00707117034883492,"XBP1/TGFB1/IL2/IL6/IL10/HLA-DQB1/HLA-DRB1/TNF",8]
["GO:0030865","cortical cytoskeleton organization","4/267","60/18866",0.0102879493733284,0.0197416338282202,0.00707117034883492,"DLG1/RAC1/CDK5/TNF",4]
["GO:0042093","T-helper cell differentiation","4/267","60/18866",0.0102879493733284,0.0197416338282202,0.00707117034883492,"IL2/IL6/IL18/MTOR",4]
["GO:0051784","negative regulation of nuclear division","4/267","60/18866",0.0102879493733284,0.0197416338282202,0.00707117034883492,"ATRX/PRKAR1A/DUSP1/LIF",4]
["GO:2000242","negative regulation of reproductive process","4/267","60/18866",0.0102879493733284,0.0197416338282202,0.00707117034883492,"IGF1/PRKAR1A/DUSP1/LIF",4]
["GO:0061097","regulation of protein tyrosine kinase activity","5/267","93/18866",0.0103499225127643,0.019852924743078,0.00711103315978991,"ERBB3/NTRK2/ACE/BDNF/CSF1R",5]
["GO:0090092","regulation of transmembrane receptor protein serine/threonine kinase signaling pathway","9/267","254/18866",0.0104430510563133,0.0200238686344748,0.00717226281214178,"CREBBP/SIRT1/EP300/SFRP1/TGFB1/MEN1/TP53/SHH/FBN1",9]
["GO:0070646","protein modification by small protein removal","10/267","300/18866",0.0106836802451096,0.0204773955715287,0.00733470966216435,"BRCA1/ESR1/EP300/HIF1A/TOR1A/TP53/VCP/AR/PTEN/PRKN",10]
["GO:0032874","positive regulation of stress-activated MAPK cascade","7/267","170/18866",0.0107453945700724,0.0205877801567043,0.00737424783881448,"VEGFA/PTK2B/IL1B/DVL3/LEP/AGER/TNF",7]
["GO:0030641","regulation of cellular pH","5/267","94/18866",0.0108085002764501,0.0207007448716209,0.00741471018096574,"GRN/MAPK1/MAPK3/BCL2/LRRK2",5]
["GO:0031343","positive regulation of cell killing","4/267","61/18866",0.0108902682934623,0.020841360517155,0.00746507669023925,"NOS2/P2RX7/IFNG/FADD",4]
["GO:0090303","positive regulation of wound healing","4/267","61/18866",0.0108902682934623,0.020841360517155,0.00746507669023925,"XBP1/PRKCE/F2/MTOR",4]
["GO:0042742","defense response to bacterium","11/267","348/18866",0.0110334635524285,0.0211073116924427,0.00756033659027063,"NOS2/GRN/TNFRSF1A/P2RX7/CRP/IL6/IL10/IL6R/F2/TNF/HP",11]
["GO:0009303","rRNA transcription","3/267","33/18866",0.0111795908578378,0.0213133627923575,0.00763414114164366,"SMARCB1/TP53/MTOR",3]
["GO:0009954","proximal/distal pattern formation","3/267","33/18866",0.0111795908578378,0.0213133627923575,0.00763414114164366,"GLI2/CTNNB1/DLL1",3]
["GO:0044319","wound healing, spreading of cells","3/267","33/18866",0.0111795908578378,0.0213133627923575,0.00763414114164366,"TOR1A/PTEN/MTOR",3]
["GO:0045736","negative regulation of cyclin-dependent protein serine/threonine kinase activity","3/267","33/18866",0.0111795908578378,0.0213133627923575,0.00763414114164366,"MEN1/CDKN2A/PTEN",3]
["GO:0090022","regulation of neutrophil chemotaxis","3/267","33/18866",0.0111795908578378,0.0213133627923575,0.00763414114164366,"RAC1/CXCL8/DPP4",3]
["GO:0090505","epiboly involved in wound healing","3/267","33/18866",0.0111795908578378,0.0213133627923575,0.00763414114164366,"TOR1A/PTEN/MTOR",3]
["GO:0120255","olefinic compound biosynthetic process","3/267","33/18866",0.0111795908578378,0.0213133627923575,0.00763414114164366,"REST/PPARGC1A/GSTM1",3]
["GO:1901797","negative regulation of signal transduction by p53 class mediator","3/267","33/18866",0.0111795908578378,0.0213133627923575,0.00763414114164366,"SIRT1/BCL2/PRKN",3]
["GO:1902745","positive regulation of lamellipodium organization","3/267","33/18866",0.0111795908578378,0.0213133627923575,0.00763414114164366,"HDAC4/RAC1/MTOR",3]
["GO:0009615","response to virus","11/267","349/18866",0.0112543374371056,0.0214476743601023,0.00768224962058753,"APOB/IFNG/STMN1/IL1B/IL6/FADD/BCL2L1/BCL2/PENK/IFNA1/TNF",11]
["GO:0051668","localization within membrane","5/267","95/18866",0.0112807744638614,0.0214816578558581,0.00769442202179956,"DLG1/APOE/RAC1/CDH13/CDK5",5]
["GO:0097194","execution phase of apoptosis","5/267","95/18866",0.0112807744638614,0.0214816578558581,0.00769442202179956,"BAX/IL6/TP53/AKT1/BCL2L1",5]
["GO:0070304","positive regulation of stress-activated protein kinase signaling cascade","7/267","172/18866",0.0114078573602384,0.0217153762103204,0.0077781365872926,"VEGFA/PTK2B/IL1B/DVL3/LEP/AGER/TNF",7]
["GO:0010803","regulation of tumor necrosis factor-mediated signaling pathway","4/267","62/18866",0.0115148821089777,0.0218773996842183,0.00783617107392179,"TNFRSF1A/ADIPOQ/PRKN/TNF",4]
["GO:0032233","positive regulation of actin filament bundle assembly","4/267","62/18866",0.0115148821089777,0.0218773996842183,0.00783617107392179,"TAC1/SFRP1/RAC1/MTOR",4]
["GO:0048488","synaptic vesicle endocytosis","4/267","62/18866",0.0115148821089777,0.0218773996842183,0.00783617107392179,"TOR1A/CDK5/SNCG/LRRK2",4]
["GO:0055081","anion homeostasis","4/267","62/18866",0.0115148821089777,0.0218773996842183,0.00783617107392179,"SIRT1/XBP1/APOE/INS",4]
["GO:0140238","presynaptic endocytosis","4/267","62/18866",0.0115148821089777,0.0218773996842183,0.00783617107392179,"TOR1A/CDK5/SNCG/LRRK2",4]
["GO:1901990","regulation of mitotic cell cycle phase transition","13/267","448/18866",0.0117441690191876,0.0223045400961596,0.00798916664875565,"BRCA1/PRKACA/BAX/EP300/CCL2/DUSP1/TP53/AKT1/PLK2/CDKN2A/MECP2/BCL2/PTEN",13]
["GO:0033209","tumor necrosis factor-mediated signaling pathway","7/267","173/18866",0.0117499616527581,0.0223070564761297,0.00799006798000241,"TNFRSF1B/TNFRSF1A/PTK2B/TP53/ADIPOQ/PRKN/TNF",7]
["GO:0002551","mast cell chemotaxis","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"VEGFA/RAC1",2]
["GO:0002863","positive regulation of inflammatory response to antigenic stimulus","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"CNR1/TNF",2]
["GO:0006983","ER overload response","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"GSK3B/TP53",2]
["GO:0007320","insemination","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"TAC1/OXT",2]
["GO:0008343","adult feeding behavior","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"NPY/LEP",2]
["GO:0009086","methionine biosynthetic process","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"MTR/MTHFR",2]
["GO:0010232","vascular transport","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"ABCB1/APOE",2]
["GO:0014745","negative regulation of muscle adaptation","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"NOS3/MTOR",2]
["GO:0021819","layer formation in cerebral cortex","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"CDK5/CTNNB1",2]
["GO:0021903","rostrocaudal neural tube patterning","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"PAX6/FGF8",2]
["GO:0032957","inositol trisphosphate metabolic process","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"POU1F1/PTK2B",2]
["GO:0035630","bone mineralization involved in bone maturation","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"IGF1/LEP",2]
["GO:0038110","interleukin-2-mediated signaling pathway","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"IL2/PTK2B",2]
["GO:0038180","nerve growth factor signaling pathway","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"NGF/BDNF",2]
["GO:0042711","maternal behavior","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"OXT/PTEN",2]
["GO:0046322","negative regulation of fatty acid oxidation","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"CNR1/AKT1",2]
["GO:0046929","negative regulation of neurotransmitter secretion","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"PRKN/NF1",2]
["GO:0051095","regulation of helicase activity","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"SIRT1/TP53",2]
["GO:0060670","branching involved in labyrinthine layer morphogenesis","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"FGFR2/IL10",2]
["GO:0060746","parental behavior","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"OXT/PTEN",2]
["GO:0060788","ectodermal placode formation","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"CTNNB1/HDAC2",2]
["GO:0070243","regulation of thymocyte apoptotic process","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"HIF1A/TP53",2]
["GO:0070278","extracellular matrix constituent secretion","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"TNFRSF1B/TNFRSF1A",2]
["GO:0070586","cell-cell adhesion involved in gastrulation","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"IL10/ADIPOQ",2]
["GO:0071107","response to parathyroid hormone","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"HDAC4/PRKACA",2]
["GO:0071257","cellular response to electrical stimulus","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"REST/PTEN",2]
["GO:0071697","ectodermal placode morphogenesis","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"CTNNB1/HDAC2",2]
["GO:0071712","ER-associated misfolded protein catabolic process","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"TOR1A/VCP",2]
["GO:0071888","macrophage apoptotic process","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"SIRT1/CDKN2A",2]
["GO:0072520","seminiferous tubule development","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"ATRX/AR",2]
["GO:0072584","caveolin-mediated endocytosis","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"MAPK1/MAPK3",2]
["GO:0072711","cellular response to hydroxyurea","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"ATRX/TIMELESS",2]
["GO:0090154","positive regulation of sphingolipid biosynthetic process","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"TNFRSF1A/TNF",2]
["GO:0090394","negative regulation of excitatory postsynaptic potential","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"PTEN/LRRK2",2]
["GO:1901298","regulation of hydrogen peroxide-mediated programmed cell death","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"HDAC6/PAWR",2]
["GO:1902510","regulation of apoptotic DNA fragmentation","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"BAX/IL6",2]
["GO:1902950","regulation of dendritic spine maintenance","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"APOE/INS",2]
["GO:2000105","positive regulation of DNA-dependent DNA replication","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"FGFR1/ATRX",2]
["GO:2000302","positive regulation of synaptic vesicle exocytosis","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"CNR1/CDK5",2]
["GO:2000304","positive regulation of ceramide biosynthetic process","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"TNFRSF1A/TNF",2]
["GO:2001053","regulation of mesenchymal cell apoptotic process","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"HIF1A/SHH",2]
["GO:2001223","negative regulation of neuron migration","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"GNRH1/ERBB4",2]
["GO:2001241","positive regulation of extrinsic apoptotic signaling pathway in absence of ligand","2/267","12/18866",0.0119935526565861,0.022403220506672,0.0080245125577568,"RET/NF1",2]
["GO:0009855","determination of bilateral symmetry","6/267","134/18866",0.0121125840375607,0.0225492921375677,0.00807683332280509,"HIF1A/FGF8/SRF/SHH/CTNNB1/DLL1",6]
["GO:0008156","negative regulation of DNA replication","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"TIMELESS/BRCA2/TP53",3]
["GO:0010762","regulation of fibroblast migration","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"TGFB1/AKT1/PRKCE",3]
["GO:0010922","positive regulation of phosphatase activity","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"IFNG/PDGFRB/MTOR",3]
["GO:0030851","granulocyte differentiation","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"GATA1/LBR/ADIPOQ",3]
["GO:0031112","positive regulation of microtubule polymerization or depolymerization","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"RAC1/MECP2/MAPT",3]
["GO:0032212","positive regulation of telomere maintenance via telomerase","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"MAPK1/MAPK3/CTNNB1",3]
["GO:0035774","positive regulation of insulin secretion involved in cellular response to glucose stimulus","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"HIF1A/RAC1/HLA-DRB1",3]
["GO:0042558","pteridine-containing compound metabolic process","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"FOLH1/MTR/MTHFR",3]
["GO:0048665","neuron fate specification","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"PAX6/GLI2/DLL1",3]
["GO:0070102","interleukin-6-mediated signaling pathway","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"IL6/IL6R/PTPN11",3]
["GO:0090504","epiboly","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"TOR1A/PTEN/MTOR",3]
["GO:1904030","negative regulation of cyclin-dependent protein kinase activity","3/267","34/18866",0.0121354499112804,0.0225492921375677,0.00807683332280509,"MEN1/CDKN2A/PTEN",3]
["GO:0007062","sister chromatid cohesion","4/267","63/18866",0.0121620756512057,0.0225492921375677,0.00807683332280509,"ATRX/SMC3/POGZ/CTNNB1",4]
["GO:0031571","mitotic G1 DNA damage checkpoint","4/267","63/18866",0.0121620756512057,0.0225492921375677,0.00807683332280509,"BAX/EP300/TP53/PLK2",4]
["GO:0046530","photoreceptor cell differentiation","4/267","63/18866",0.0121620756512057,0.0225492921375677,0.00807683332280509,"PAX6/VEGFA/NTRK2/PRKCI",4]
["GO:0051893","regulation of focal adhesion assembly","4/267","63/18866",0.0121620756512057,0.0225492921375677,0.00807683332280509,"SFRP1/VEGFA/RAC1/PTEN",4]
["GO:0055008","cardiac muscle tissue morphogenesis","4/267","63/18866",0.0121620756512057,0.0225492921375677,0.00807683332280509,"COL11A1/FGFR2/TGFB1/CHD7",4]
["GO:0090109","regulation of cell-substrate junction assembly","4/267","63/18866",0.0121620756512057,0.0225492921375677,0.00807683332280509,"SFRP1/VEGFA/RAC1/PTEN",4]
["GO:2000514","regulation of CD4-positive, alpha-beta T cell activation","4/267","63/18866",0.0121620756512057,0.0225492921375677,0.00807683332280509,"IL2/IFNG/IL18/AGER",4]
["GO:0046634","regulation of alpha-beta T cell activation","5/267","97/18866",0.0122671342948078,0.022718769114976,0.00813753754758647,"IL2/IFNG/IL18/SHH/AGER",5]
["GO:1990868","response to chemokine","5/267","97/18866",0.0122671342948078,0.022718769114976,0.00813753754758647,"HIF1A/CCL2/DUSP1/PTK2B/CXCL8",5]
["GO:1990869","cellular response to chemokine","5/267","97/18866",0.0122671342948078,0.022718769114976,0.00813753754758647,"HIF1A/CCL2/DUSP1/PTK2B/CXCL8",5]
["GO:0010921","regulation of phosphatase activity","7/267","175/18866",0.0124563404063925,0.0230606257505071,0.00825998569578706,"GSK3B/IFNG/PDGFRB/PPP1R1B/DRD2/MTOR/TNF",7]
["GO:0009799","specification of symmetry","6/267","135/18866",0.012530346691036,0.0231890367043524,0.0083059806593852,"HIF1A/FGF8/SRF/SHH/CTNNB1/DLL1",6]
["GO:0006942","regulation of striated muscle contraction","5/267","98/18866",0.0127815737485605,0.0236452010843137,0.00846937220366386,"HDAC4/PRKACA/DLG1/ATP2A2/DMD",5]
["GO:0032507","maintenance of protein location in cell","4/267","64/18866",0.012832123871519,0.023694820447668,0.00848714514859495,"TSPO/SYNE1/AKT1/CDK5",4]
["GO:0044783","G1 DNA damage checkpoint","4/267","64/18866",0.012832123871519,0.023694820447668,0.00848714514859495,"BAX/EP300/TP53/PLK2",4]
["GO:0044819","mitotic G1/S transition checkpoint","4/267","64/18866",0.012832123871519,0.023694820447668,0.00848714514859495,"BAX/EP300/TP53/PLK2",4]
["GO:0046637","regulation of alpha-beta T cell differentiation","4/267","64/18866",0.012832123871519,0.023694820447668,0.00848714514859495,"IL2/IFNG/IL18/SHH",4]
["GO:0051926","negative regulation of calcium ion transport","4/267","64/18866",0.012832123871519,0.023694820447668,0.00848714514859495,"PTGS2/DRD2/NOS3/BCL2",4]
["GO:0045727","positive regulation of translation","6/267","136/18866",0.0129581320933957,0.0239186519564972,0.00856731838765613,"MAPK1/MAPK3/PTK2B/IL6/MTOR/TNF",6]
["GO:0030178","negative regulation of Wnt signaling pathway","8/267","219/18866",0.0129860742277068,0.0239613705169772,0.00858261956388296,"GSK3B/TSC2/SFRP1/APOE/DVL3/SHH/PRKN/TLE1",8]
["GO:0001914","regulation of T cell mediated cytotoxicity","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"P2RX7/FADD/AGER",3]
["GO:0009112","nucleobase metabolic process","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"MAPK1/TTR/MTOR",3]
["GO:0032801","receptor catabolic process","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"TGFB1/APOE/CDK5",3]
["GO:0033144","negative regulation of intracellular steroid hormone receptor signaling pathway","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"BRCA1/SIRT1/SFRP1",3]
["GO:0050779","RNA destabilization","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"TNFRSF1B/FTO/LIN28B",3]
["GO:0060674","placenta blood vessel development","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"MAPK1/AKT1/MAP2K1",3]
["GO:0065005","protein-lipid complex assembly","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"PRKACA/APOB/APOE",3]
["GO:0071312","cellular response to alkaloid","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"PPARGC1A/OPRM1/BCL2L1",3]
["GO:0097009","energy homeostasis","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"PPARGC1A/PIK3CA/DLL1",3]
["GO:0110111","negative regulation of animal organ morphogenesis","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"CTNNB1/BCL2/TNF",3]
["GO:1900077","negative regulation of cellular response to insulin stimulus","3/267","35/18866",0.0131368127689611,0.0241413714226804,0.00864709330897656,"TSC2/IL1B/LPL",3]
["GO:0006940","regulation of smooth muscle contraction","4/267","65/18866",0.0135252917880895,0.0247914030462301,0.00887992532188113,"PTGS2/OXT/SRF/SOD1",4]
["GO:0007588","excretion","4/267","65/18866",0.0135252917880895,0.0247914030462301,0.00887992532188113,"TAC1/COMT/OXT/DRD2",4]
["GO:0031640","killing of cells of other organism","4/267","65/18866",0.0135252917880895,0.0247914030462301,0.00887992532188113,"NOS2/P2RX7/IFNG/F2",4]
["GO:0035773","insulin secretion involved in cellular response to glucose stimulus","4/267","65/18866",0.0135252917880895,0.0247914030462301,0.00887992532188113,"HIF1A/RAC1/PRKCE/HLA-DRB1",4]
["GO:0046782","regulation of viral transcription","4/267","65/18866",0.0135252917880895,0.0247914030462301,0.00887992532188113,"REST/SMARCB1/EP300/JUN",4]
["GO:0051205","protein insertion into membrane","4/267","65/18866",0.0135252917880895,0.0247914030462301,0.00887992532188113,"BAX/MAPK8/TP53/BCL2",4]
["GO:0090181","regulation of cholesterol metabolic process","4/267","65/18866",0.0135252917880895,0.0247914030462301,0.00887992532188113,"APOB/GNB3/APOE/SOD1",4]
["GO:0006941","striated muscle contraction","7/267","178/18866",0.0135725940407429,0.0248689768974052,0.00890771116377487,"HDAC4/PRKACA/DLG1/PIK3CA/ATP2A2/MTOR/DMD",7]
["GO:0009165","nucleotide biosynthetic process","9/267","266/18866",0.0137860749848567,0.0252508702859096,0.00904449990318243,"NOS2/ACSL4/PTGS2/MAPK1/TGFB1/PPARGC1A/IDO1/NOS3/VCP",9]
["GO:0001508","action potential","6/267","138/18866",0.0138442351004999,0.0253388071322566,0.00907599762144983,"TAC1/DLG1/CNR1/NTRK2/ATP2A2/DMD",6]
["GO:0072329","monocarboxylic acid catabolic process","6/267","138/18866",0.0138442351004999,0.0253388071322566,0.00907599762144983,"CNR1/IDUA/AKT1/LEP/ADIPOQ/MTOR",6]
["GO:0002679","respiratory burst involved in defense response","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"GRN/INS",2]
["GO:0009650","UV protection","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"GPX1/MC1R",2]
["GO:0010745","negative regulation of macrophage derived foam cell differentiation","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"CRP/ADIPOQ",2]
["GO:0016264","gap junction assembly","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"IL1B/ACE",2]
["GO:0021520","spinal cord motor neuron cell fate specification","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"PAX6/GLI2",2]
["GO:0021794","thalamus development","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"SRD5A1/SHH",2]
["GO:0021978","telencephalon regionalization","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"PAX6/SHH",2]
["GO:0031053","primary miRNA processing","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"IL6/LIN28B",2]
["GO:0031953","negative regulation of protein autophosphorylation","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"JUN/ADIPOQ",2]
["GO:0032096","negative regulation of response to food","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"LEP/CCK",2]
["GO:0032099","negative regulation of appetite","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"LEP/CCK",2]
["GO:0032230","positive regulation of synaptic transmission, GABAergic","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"TAC1/PRKCE",2]
["GO:0032352","positive regulation of hormone metabolic process","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"HIF1A/PPARGC1A",2]
["GO:0032725","positive regulation of granulocyte macrophage colony-stimulating factor production","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"IL1B/IL18",2]
["GO:0033127","regulation of histone phosphorylation","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"MAPK3/IL1B",2]
["GO:0033145","positive regulation of intracellular steroid hormone receptor signaling pathway","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"KMT2D/AR",2]
["GO:0033605","positive regulation of catecholamine secretion","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"OXT/GDNF",2]
["GO:0043201","response to leucine","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"PPARGC1A/MTOR",2]
["GO:0043568","positive regulation of insulin-like growth factor receptor signaling pathway","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"IGF1/AR",2]
["GO:0048096","chromatin-mediated maintenance of transcription","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"ARID1B/CTNNB1",2]
["GO:0048505","regulation of timing of cell differentiation","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"PAX6/DLL1",2]
["GO:0048715","negative regulation of oligodendrocyte differentiation","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"CTNNB1/NF1",2]
["GO:0060456","positive regulation of digestive system process","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"TAC1/OXT",2]
["GO:0061043","regulation of vascular wound healing","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"XBP1/TNF",2]
["GO:0061430","bone trabecula morphogenesis","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"SFRP1/COL1A1",2]
["GO:0061469","regulation of type B pancreatic cell proliferation","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"SFRP1/MEN1",2]
["GO:0070914","UV-damage excision repair","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"SIRT1/MC1R",2]
["GO:0071352","cellular response to interleukin-2","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"IL2/PTK2B",2]
["GO:0071696","ectodermal placode development","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"CTNNB1/HDAC2",2]
["GO:0072182","regulation of nephron tubule epithelial cell differentiation","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"LIF/CTNNB1",2]
["GO:0072683","T cell extravasation","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"CCL2/FADD",2]
["GO:0072710","response to hydroxyurea","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"ATRX/TIMELESS",2]
["GO:0090677","reversible differentiation","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"SOD2/DNMT1",2]
["GO:0097152","mesenchymal cell apoptotic process","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"HIF1A/SHH",2]
["GO:0097531","mast cell migration","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"VEGFA/RAC1",2]
["GO:1900272","negative regulation of long-term synaptic potentiation","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"APOE/AGER",2]
["GO:1903025","regulation of RNA polymerase II regulatory region sequence-specific DNA binding","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"EP300/LIF",2]
["GO:1990403","embryonic brain development","2/267","13/18866",0.0140429837914282,0.0253494642337675,0.00907981484249969,"CTNNB1/MED12",2]
["GO:0002701","negative regulation of production of molecular mediator of immune response","3/267","36/18866",0.014183974921391,0.0255117387545048,0.00913793925050937,"TGFB1/IL10/TNF",3]
["GO:0010543","regulation of platelet activation","3/267","36/18866",0.014183974921391,0.0255117387545048,0.00913793925050937,"APOE/NOS3/F2",3]
["GO:0014808","release of sequestered calcium ion into cytosol by sarcoplasmic reticulum","3/267","36/18866",0.014183974921391,0.0255117387545048,0.00913793925050937,"PRKACA/CHD7/DMD",3]
["GO:0021955","central nervous system neuron axonogenesis","3/267","36/18866",0.014183974921391,0.0255117387545048,0.00913793925050937,"GLI2/PTEN/DCC",3]
["GO:0033762","response to glucagon","3/267","36/18866",0.014183974921391,0.0255117387545048,0.00913793925050937,"PRKACA/PRKAR1A/CREB1",3]
["GO:0042491","inner ear auditory receptor cell differentiation","3/267","36/18866",0.014183974921391,0.0255117387545048,0.00913793925050937,"FGFR1/SOD1/DLL1",3]
["GO:0051973","positive regulation of telomerase activity","3/267","36/18866",0.014183974921391,0.0255117387545048,0.00913793925050937,"MAPK1/MAPK3/CTNNB1",3]
["GO:0060323","head morphogenesis","3/267","36/18866",0.014183974921391,0.0255117387545048,0.00913793925050937,"EP300/COL1A1/PTPN11",3]
["GO:0071634","regulation of transforming growth factor beta production","3/267","36/18866",0.014183974921391,0.0255117387545048,0.00913793925050937,"PTGS2/HIF1A/CREB1",3]
["GO:1901385","regulation of voltage-gated calcium channel activity","3/267","36/18866",0.014183974921391,0.0255117387545048,0.00913793925050937,"DRD2/CDK5/DMD",3]
["GO:0007585","respiratory gaseous exchange by respiratory system","4/267","66/18866",0.0142418344431901,0.025588153787279,0.0091653100202572,"FTO/KDM6A/EDNRA/MECP2",4]
["GO:0150116","regulation of cell-substrate junction organization","4/267","66/18866",0.0142418344431901,0.025588153787279,0.0091653100202572,"SFRP1/VEGFA/RAC1/PTEN",4]
["GO:1905207","regulation of cardiocyte differentiation","4/267","66/18866",0.0142418344431901,0.025588153787279,0.0091653100202572,"IGF1/TGFB1/DLL1/MTOR",4]
["GO:0002433","immune response-regulating cell surface receptor signaling pathway involved in phagocytosis","6/267","139/18866",0.0143027817066931,0.0256791762177341,0.0091979129505371,"MAPK1/MAPK3/PIK3CA/RAC1/PIK3R1/PRKCE",6]
["GO:0038096","Fc-gamma receptor signaling pathway involved in phagocytosis","6/267","139/18866",0.0143027817066931,0.0256791762177341,0.0091979129505371,"MAPK1/MAPK3/PIK3CA/RAC1/PIK3R1/PRKCE",6]
["GO:1901293","nucleoside phosphate biosynthetic process","9/267","269/18866",0.0147333761905749,0.0264427560458449,0.00947141630322251,"NOS2/ACSL4/PTGS2/MAPK1/TGFB1/PPARGC1A/IDO1/NOS3/VCP",9]
["GO:0007266","Rho protein signal transduction","6/267","140/18866",0.0147718089897383,0.0265022070735765,0.00949271080945039,"NGFR/PDGFRB/STMN1/APOE/RAC1/CDH13",6]
["GO:0002548","monocyte chemotaxis","4/267","67/18866",0.0149819968706147,0.0268077191109297,0.00960214084338484,"CCL2/DUSP1/IL6/IL6R",4]
["GO:0007040","lysosome organization","4/267","67/18866",0.0149819968706147,0.0268077191109297,0.00960214084338484,"GRN/P2RX7/LRRK2/MTOR",4]
["GO:0030239","myofibril assembly","4/267","67/18866",0.0149819968706147,0.0268077191109297,0.00960214084338484,"PRKAR1A/SRF/PDGFRB/NEB",4]
["GO:0034332","adherens junction organization","4/267","67/18866",0.0149819968706147,0.0268077191109297,0.00960214084338484,"VEGFA/ADAM10/CDH13/CTNNB1",4]
["GO:0051965","positive regulation of synapse assembly","4/267","67/18866",0.0149819968706147,0.0268077191109297,0.00960214084338484,"ADNP/OXT/NTRK2/BDNF",4]
["GO:0080171","lytic vacuole organization","4/267","67/18866",0.0149819968706147,0.0268077191109297,0.00960214084338484,"GRN/P2RX7/LRRK2/MTOR",4]
["GO:0022600","digestive system process","5/267","102/18866",0.0149850478747456,0.0268077191109297,0.00960214084338484,"TAC1/OXT/VDR/LEP/SERPINA3",5]
["GO:0032006","regulation of TOR signaling","5/267","102/18866",0.0149850478747456,0.0268077191109297,0.00960214084338484,"SIRT1/HIF1A/TSC2/PIK3CA/LEP",5]
["GO:1903322","positive regulation of protein modification by small protein conjugation or removal","6/267","141/18866",0.0152514283066715,0.0272717228590669,0.00976834033700965,"BRCA1/HDAC4/VCP/PTEN/PRKN/LRRK2",6]
["GO:0030212","hyaluronan metabolic process","3/267","37/18866",0.0152771898331284,0.0272717228590669,0.00976834033700965,"TGFB1/IL1B/AKT1",3]
["GO:0045191","regulation of isotype switching","3/267","37/18866",0.0152771898331284,0.0272717228590669,0.00976834033700965,"TGFB1/IL2/IL10",3]
["GO:0045730","respiratory burst","3/267","37/18866",0.0152771898331284,0.0272717228590669,0.00976834033700965,"GRN/RAC1/INS",3]
["GO:1903514","release of sequestered calcium ion into cytosol by endoplasmic reticulum","3/267","37/18866",0.0152771898331284,0.0272717228590669,0.00976834033700965,"PRKACA/CHD7/DMD",3]
["GO:1904358","positive regulation of telomere maintenance via telomere lengthening","3/267","37/18866",0.0152771898331284,0.0272717228590669,0.00976834033700965,"MAPK1/MAPK3/CTNNB1",3]
["GO:2001020","regulation of response to DNA damage stimulus","8/267","226/18866",0.0154316990319347,0.0275376959494103,0.00986360808669994,"BRCA1/FUS/SIRT1/TIMELESS/TP53/BCL2L1/BCL2/MAPT",8]
["GO:0006885","regulation of pH","5/267","103/18866",0.0155731681083274,0.0277603814226628,0.00994337083223968,"GRN/MAPK1/MAPK3/BCL2/LRRK2",5]
["GO:0030593","neutrophil chemotaxis","5/267","103/18866",0.0155731681083274,0.0277603814226628,0.00994337083223968,"CCL2/IL1B/RAC1/CXCL8/DPP4",5]
["GO:0034766","negative regulation of ion transmembrane transport","5/267","103/18866",0.0155731681083274,0.0277603814226628,0.00994337083223968,"AKT1/DRD2/PRKCE/PTEN/MTOR",5]
["GO:0007051","spindle organization","7/267","183/18866",0.0155896881059218,0.0277700009678444,0.00994681641548011,"DLG1/ATRX/SMC3/STMN1/PLK2/VCP/MECP2",7]
["GO:0030177","positive regulation of Wnt signaling pathway","7/267","183/18866",0.0155896881059218,0.0277700009678444,0.00994681641548011,"FGFR2/SFRP1/TGFB1/COL1A1/SHH/VCP/LRRK2",7]
["GO:0038094","Fc-gamma receptor signaling pathway","6/267","142/18866",0.0157417496922709,0.0280084959976799,0.0100322419176443,"MAPK1/MAPK3/PIK3CA/RAC1/PIK3R1/PRKCE",6]
["GO:0071479","cellular response to ionizing radiation","4/267","68/18866",0.0157460140727994,0.0280084959976799,0.0100322419176443,"SIRT1/SFRP1/TP53/BCL2L1",4]
["GO:0072577","endothelial cell apoptotic process","4/267","68/18866",0.0157460140727994,0.0280084959976799,0.0100322419176443,"CCL2/IL10/PRKCI/TNF",4]
["GO:0099072","regulation of postsynaptic membrane neurotransmitter receptor levels","4/267","68/18866",0.0157460140727994,0.0280084959976799,0.0100322419176443,"DLG1/ADAM10/PRKCI/GPC6",4]
["GO:0006611","protein export from nucleus","7/267","184/18866",0.0160173379676905,0.0284472945415596,0.0101894132682829,"PRKACA/GSK3B/TGFB1/IL1B/TP53/CDK5/PTPN11",7]
["GO:0090090","negative regulation of canonical Wnt signaling pathway","7/267","184/18866",0.0160173379676905,0.0284472945415596,0.0101894132682829,"GSK3B/SFRP1/APOE/DVL3/SHH/PRKN/TLE1",7]
["GO:0048525","negative regulation of viral process","5/267","104/18866",0.0161765066590395,0.0284472945415596,0.0101894132682829,"REST/CRP/JUN/PRKN/TNF",5]
["GO:0120034","positive regulation of plasma membrane bounded cell projection assembly","5/267","104/18866",0.0161765066590395,0.0284472945415596,0.0101894132682829,"HDAC4/P2RX7/SRF/RAC1/MTOR",5]
["GO:0010421","hydrogen peroxide-mediated programmed cell death","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"HDAC6/PAWR",2]
["GO:0010752","regulation of cGMP-mediated signaling","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"PTK2B/PDE11A",2]
["GO:0010917","negative regulation of mitochondrial membrane potential","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"BAX/MAPT",2]
["GO:0014874","response to stimulus involved in regulation of muscle adaptation","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"HDAC4/PPARGC1A",2]
["GO:0019896","axonal transport of mitochondrion","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"HIF1A/MAPT",2]
["GO:0021781","glial cell fate commitment","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"PAX6/CTNNB1",2]
["GO:0030213","hyaluronan biosynthetic process","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"TGFB1/IL1B",2]
["GO:0031282","regulation of guanylate cyclase activity","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"NOS2/NOS3",2]
["GO:0032042","mitochondrial DNA metabolic process","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"PPARGC1A/TP53",2]
["GO:0033604","negative regulation of catecholamine secretion","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"CNR1/DRD2",2]
["GO:0034392","negative regulation of smooth muscle cell apoptotic process","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"IGF1/DNMT1",2]
["GO:0035112","genitalia morphogenesis","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"CTNNB1/AR",2]
["GO:0035358","regulation of peroxisome proliferator activated receptor signaling pathway","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"SIRT1/LEP",2]
["GO:0035751","regulation of lysosomal lumen pH","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"GRN/LRRK2",2]
["GO:0040034","regulation of development, heterochronic","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"PAX6/DLL1",2]
["GO:0042659","regulation of cell fate specification","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"FGFR1/AR",2]
["GO:0043922","negative regulation by host of viral transcription","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"REST/JUN",2]
["GO:0044154","histone H3-K14 acetylation","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"SIRT1/KMT2A",2]
["GO:0044793","negative regulation by host of viral process","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"CRP/PRKN",2]
["GO:0044794","positive regulation by host of viral process","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"APOE/CSF1R",2]
["GO:0045059","positive thymic T cell selection","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"SRF/SHH",2]
["GO:0045472","response to ether","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"OXT/PPARGC1A",2]
["GO:0045591","positive regulation of regulatory T cell differentiation","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"IL2/IFNG",2]
["GO:0047484","regulation of response to osmotic stress","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"PTGS2/ABCB1",2]
["GO:0050667","homocysteine metabolic process","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"COMT/MTHFR",2]
["GO:0050872","white fat cell differentiation","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"SIRT1/PER2",2]
["GO:0051547","regulation of keratinocyte migration","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"PTEN/MTOR",2]
["GO:0061051","positive regulation of cell growth involved in cardiac muscle cell development","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"IGF1/MTOR",2]
["GO:0070234","positive regulation of T cell apoptotic process","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"IDO1/TP53",2]
["GO:0070669","response to interleukin-2","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"IL2/PTK2B",2]
["GO:0071361","cellular response to ethanol","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"PRKCE/PTEN",2]
["GO:0090399","replicative senescence","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"TP53/CDKN2A",2]
["GO:0097468","programmed cell death in response to reactive oxygen species","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"HDAC6/PAWR",2]
["GO:0098814","spontaneous synaptic transmission","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"PRKN/AGER",2]
["GO:1900239","regulation of phenotypic switching","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"SOD2/DNMT1",2]
["GO:1901836","regulation of transcription of nucleolar large rRNA by RNA polymerase I","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"SMARCB1/MTOR",2]
["GO:1902894","negative regulation of pri-miRNA transcription by RNA polymerase II","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"HDAC4/SRF",2]
["GO:1903624","regulation of DNA catabolic process","2/267","14/18866",0.0162319932202891,0.0284472945415596,0.0101894132682829,"BAX/IL6",2]
["GO:0003298","physiological muscle hypertrophy","3/267","38/18866",0.0164166704048104,0.0286903868852706,0.0102764854623999,"IGF1/PDLIM5/MTOR",3]
["GO:0003301","physiological cardiac muscle hypertrophy","3/267","38/18866",0.0164166704048104,0.0286903868852706,0.0102764854623999,"IGF1/PDLIM5/MTOR",3]
["GO:0006361","transcription initiation from RNA polymerase I promoter","3/267","38/18866",0.0164166704048104,0.0286903868852706,0.0102764854623999,"SMARCB1/MAPK3/TBP",3]
["GO:0010591","regulation of lamellipodium assembly","3/267","38/18866",0.0164166704048104,0.0286903868852706,0.0102764854623999,"HDAC4/RAC1/MTOR",3]
["GO:0045777","positive regulation of blood pressure","3/267","38/18866",0.0164166704048104,0.0286903868852706,0.0102764854623999,"OXT/CNR1/ACE",3]
["GO:0061049","cell growth involved in cardiac muscle cell development","3/267","38/18866",0.0164166704048104,0.0286903868852706,0.0102764854623999,"IGF1/PDLIM5/MTOR",3]
["GO:0071604","transforming growth factor beta production","3/267","38/18866",0.0164166704048104,0.0286903868852706,0.0102764854623999,"PTGS2/HIF1A/CREB1",3]
["GO:2000403","positive regulation of lymphocyte migration","3/267","38/18866",0.0164166704048104,0.0286903868852706,0.0102764854623999,"PTK2B/ADAM10/FADD",3]
["GO:0046488","phosphatidylinositol metabolic process","7/267","185/18866",0.0164532507127122,0.0287442550064983,0.0102957802515186,"HTR2A/PDGFRB/PIK3CA/PIK3R1/INPPL1/PTEN/CSF1R",7]
["GO:0030032","lamellipodium assembly","4/267","69/18866",0.0165341110072438,0.0288653203703386,0.0103391441300358,"HDAC4/RAC1/CDH13/MTOR",4]
["GO:0035914","skeletal muscle cell differentiation","4/267","69/18866",0.0165341110072438,0.0288653203703386,0.0103391441300358,"S100B/ATF3/FOS/PAX5",4]
["GO:1902850","microtubule cytoskeleton organization involved in mitosis","6/267","144/18866",0.0167549319893311,0.0292406065790738,0.0104735662723279,"PAX6/SMC3/STMN1/PLK2/VCP/MECP2",6]
["GO:1902414","protein localization to cell junction","5/267","105/18866",0.016795216482923,0.0293006694267066,0.0104950799236773,"DLG1/ADAM10/CDK5/GPC6/MAPT",5]
["GO:0001738","morphogenesis of a polarized epithelium","6/267","145/18866",0.017278006049858,0.0301218869437644,0.0107892282706222,"SFRP1/RAC1/DVL3/FZD2/GPC6/MED12",6]
["GO:0002431","Fc receptor mediated stimulatory signaling pathway","6/267","145/18866",0.017278006049858,0.0301218869437644,0.0107892282706222,"MAPK1/MAPK3/PIK3CA/RAC1/PIK3R1/PRKCE",6]
["GO:0050771","negative regulation of axonogenesis","4/267","70/18866",0.0173465025818394,0.0302307460352964,0.0108282200373088,"NGFR/CDK5/PTEN/DCC",4]
["GO:0032271","regulation of protein polymerization","8/267","231/18866",0.0173720993291706,0.0302647913295704,0.0108404145738645,"DLG1/STMN1/PTK2B/RAC1/MECP2/PRKCE/MAPT/MTOR",8]
["GO:0032414","positive regulation of ion transmembrane transporter activity","5/267","106/18866",0.0174294471037242,0.0303541086114039,0.0108724067443421,"ABCB1/CCL2/IFNG/CDK5/DMD",5]
["GO:0000578","embryonic axis specification","3/267","39/18866",0.0176025903978508,0.0306129341192856,0.0109651143324162,"KDM6A/CTNNB1/PTCH1",3]
["GO:0030866","cortical actin cytoskeleton organization","3/267","39/18866",0.0176025903978508,0.0306129341192856,0.0109651143324162,"DLG1/CDK5/TNF",3]
["GO:1902229","regulation of intrinsic apoptotic signaling pathway in response to DNA damage","3/267","39/18866",0.0176025903978508,0.0306129341192856,0.0109651143324162,"SIRT1/BCL2L1/BCL2",3]
["GO:2000249","regulation of actin cytoskeleton reorganization","3/267","39/18866",0.0176025903978508,0.0306129341192856,0.0109651143324162,"PTK2B/CDK5/CSF1R",3]
["GO:0000018","regulation of DNA recombination","5/267","107/18866",0.0180793445652086,0.0314311167876346,0.0112581756400416,"FUS/TGFB1/IL2/TIMELESS/IL10",5]
["GO:0045739","positive regulation of DNA repair","4/267","71/18866",0.0181833936587267,0.0315900085379341,0.0113150883881539,"BRCA1/FUS/SIRT1/TIMELESS",4]
["GO:0050891","multicellular organismal water homeostasis","4/267","71/18866",0.0181833936587267,0.0315900085379341,0.0113150883881539,"PRKACA/PRKAR1A/SRF/STMN1",4]
["GO:0007189","adenylate cyclase-activating G protein-coupled receptor signaling pathway","6/267","147/18866",0.0183576419917125,0.0318061648843131,0.011392512494007,"GNAS/OPRM1/CNR1/GNAL/DRD2/MC1R",6]
["GO:0044409","entry into host","6/267","147/18866",0.0183576419917125,0.0318061648843131,0.011392512494007,"HTR2A/NCAM1/CTNNB1/CXCL8/HLA-DRB1/DPP4",6]
["GO:1904064","positive regulation of cation transmembrane transport","6/267","147/18866",0.0183576419917125,0.0318061648843131,0.011392512494007,"BAX/CCL2/IFNG/CDK5/F2/DMD",6]
["GO:0014048","regulation of glutamate secretion","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"P2RX7/CCK",2]
["GO:0014733","regulation of skeletal muscle adaptation","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"ATP2A2/MTOR",2]
["GO:0030238","male sex determination","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"GNRH1/AR",2]
["GO:0032105","negative regulation of response to extracellular stimulus","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"LEP/CCK",2]
["GO:0032108","negative regulation of response to nutrient levels","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"LEP/CCK",2]
["GO:0032645","regulation of granulocyte macrophage colony-stimulating factor production","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"IL1B/IL18",2]
["GO:0033689","negative regulation of osteoblast proliferation","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"SFRP1/BCL2",2]
["GO:0035635","entry of bacterium into host cell","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"CTNNB1/CXCL8",2]
["GO:0042159","lipoprotein catabolic process","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"APOB/APOE",2]
["GO:0042754","negative regulation of circadian rhythm","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"PER2/DRD2",2]
["GO:0042976","activation of Janus kinase activity","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"PTK2B/IL6R",2]
["GO:0043584","nose development","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"HESX1/CHD7",2]
["GO:0045475","locomotor rhythm","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"PTEN/MTOR",2]
["GO:0045820","negative regulation of glycolytic process","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"HDAC4/PPARGC1A",2]
["GO:0045837","negative regulation of membrane potential","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"BAX/MAPT",2]
["GO:0048070","regulation of developmental pigmentation","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"BAX/BCL2",2]
["GO:0048368","lateral mesoderm development","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"FGFR1/SHH",2]
["GO:0048712","negative regulation of astrocyte differentiation","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"F2/NF1",2]
["GO:0051589","negative regulation of neurotransmitter transport","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"PRKN/NF1",2]
["GO:0055057","neuroblast division","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"FGFR2/FGFR1",2]
["GO:0060579","ventral spinal cord interneuron fate commitment","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"PAX6/GLI2",2]
["GO:0060581","cell fate commitment involved in pattern specification","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"PAX6/GLI2",2]
["GO:0060766","negative regulation of androgen receptor signaling pathway","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"SIRT1/SFRP1",2]
["GO:0070885","negative regulation of calcineurin-NFAT signaling cascade","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"GSK3B/MTOR",2]
["GO:0072044","collecting duct development","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"SHH/PTCH1",2]
["GO:0072075","metanephric mesenchyme development","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"PDGFRB/SHH",2]
["GO:0072160","nephron tubule epithelial cell differentiation","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"LIF/CTNNB1",2]
["GO:0072498","embryonic skeletal joint development","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"COL2A1/CTNNB1",2]
["GO:0072567","chemokine (C-X-C motif) ligand 2 production","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"LPL/TNF",2]
["GO:0099171","presynaptic modulation of chemical synaptic transmission","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"CNR1/CDK5",2]
["GO:0106057","negative regulation of calcineurin-mediated signaling","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"GSK3B/MTOR",2]
["GO:1903960","negative regulation of anion transmembrane transport","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"AKT1/MTOR",2]
["GO:2000341","regulation of chemokine (C-X-C motif) ligand 2 production","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"LPL/TNF",2]
["GO:2000402","negative regulation of lymphocyte migration","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"CCL2/AKT1",2]
["GO:2001028","positive regulation of endothelial cell chemotaxis","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"FGFR1/VEGFA",2]
["GO:2001171","positive regulation of ATP biosynthetic process","2/267","15/18866",0.0185562504121779,0.0318061648843131,0.011392512494007,"PPARGC1A/VCP",2]
["GO:0002714","positive regulation of B cell mediated immunity","3/267","40/18866",0.018835085822624,0.0322067066823156,0.0115359808264737,"TGFB1/IL2/TNF",3]
["GO:0002891","positive regulation of immunoglobulin mediated immune response","3/267","40/18866",0.018835085822624,0.0322067066823156,0.0115359808264737,"TGFB1/IL2/TNF",3]
["GO:0016572","histone phosphorylation","3/267","40/18866",0.018835085822624,0.0322067066823156,0.0115359808264737,"MAPK3/IL1B/CDK5",3]
["GO:0040036","regulation of fibroblast growth factor receptor signaling pathway","3/267","40/18866",0.018835085822624,0.0322067066823156,0.0115359808264737,"NGFR/OTX2/CTNNB1",3]
["GO:0045746","negative regulation of Notch signaling pathway","3/267","40/18866",0.018835085822624,0.0322067066823156,0.0115359808264737,"NOTCH3/AKT1/DLL1",3]
["GO:0071526","semaphorin-plexin signaling pathway","3/267","40/18866",0.018835085822624,0.0322067066823156,0.0115359808264737,"RAC1/NCAM1/GDNF",3]
["GO:1903427","negative regulation of reactive oxygen species biosynthetic process","3/267","40/18866",0.018835085822624,0.0322067066823156,0.0115359808264737,"TSPO/IL10/INS",3]
["GO:0042440","pigment metabolic process","4/267","72/18866",0.0190449790663118,0.0325321862737238,0.011652562952145,"TSPO/PPARGC1A/BCL2/MC1R",4]
["GO:0043647","inositol phosphate metabolic process","4/267","72/18866",0.0190449790663118,0.0325321862737238,0.011652562952145,"POU1F1/PTK2B/INPPL1/PTEN",4]
["GO:0061035","regulation of cartilage development","4/267","72/18866",0.0190449790663118,0.0325321862737238,0.011652562952145,"GLI2/CTNNB1/LEP/PTPN11",4]
["GO:0016525","negative regulation of angiogenesis","7/267","192/18866",0.0197424957187307,0.0337121344472033,0.0120752034797766,"NGFR/PLK2/CTNNB1/MECP2/PRL/NF1/TNF",7]
["GO:0016579","protein deubiquitination","9/267","283/18866",0.0197993641872053,0.0337976838928944,0.0121058460653394,"BRCA1/ESR1/EP300/HIF1A/TP53/VCP/AR/PTEN/PRKN",9]
["GO:0010611","regulation of cardiac muscle hypertrophy","4/267","73/18866",0.0199314436190854,0.0340115167430257,0.0121824379281311,"IGF1/TNFRSF1B/TNFRSF1A/MTOR",4]
["GO:0090263","positive regulation of canonical Wnt signaling pathway","6/267","150/18866",0.0200623362500739,0.0342231789875706,0.0122582523111055,"FGFR2/SFRP1/TGFB1/COL1A1/VCP/LRRK2",6]
["GO:0002251","organ or tissue specific immune response","3/267","41/18866",0.0201142562909371,0.0342298846832477,0.0122606541952076,"NOS2/IL6/IL6R",3]
["GO:0030890","positive regulation of B cell proliferation","3/267","41/18866",0.0201142562909371,0.0342298846832477,0.0122606541952076,"CD38/IL2/BCL2",3]
["GO:0035136","forelimb morphogenesis","3/267","41/18866",0.0201142562909371,0.0342298846832477,0.0122606541952076,"ATRX/SHH/CTNNB1",3]
["GO:0048286","lung alveolus development","3/267","41/18866",0.0201142562909371,0.0342298846832477,0.0122606541952076,"FGFR2/CREB1/LIF",3]
["GO:0050434","positive regulation of viral transcription","3/267","41/18866",0.0201142562909371,0.0342298846832477,0.0122606541952076,"SMARCB1/EP300/JUN",3]
["GO:0070317","negative regulation of G0 to G1 transition","3/267","41/18866",0.0201142562909371,0.0342298846832477,0.0122606541952076,"BRCA1/L3MBTL2/EHMT1",3]
["GO:1905209","positive regulation of cardiocyte differentiation","3/267","41/18866",0.0201142562909371,0.0342298846832477,0.0122606541952076,"IGF1/TGFB1/MTOR",3]
["GO:0000077","DNA damage checkpoint","6/267","151/18866",0.0206536930491771,0.035111981407743,0.0125766086018859,"BRCA1/BAX/EP300/TP53/PLK2/PTPN11",6]
["GO:0007030","Golgi organization","6/267","151/18866",0.0206536930491771,0.035111981407743,0.0125766086018859,"MAPK1/MAPK3/MAP2K2/SYNE1/MAP2K1/LRRK2",6]
["GO:0050871","positive regulation of B cell activation","6/267","151/18866",0.0206536930491771,0.035111981407743,0.0125766086018859,"CD38/XBP1/TGFB1/IL2/IL6/BCL2",6]
["GO:2000181","negative regulation of blood vessel morphogenesis","7/267","194/18866",0.0207609930441924,0.0352823819842248,0.0126376436466206,"NGFR/PLK2/CTNNB1/MECP2/PRL/NF1/TNF",7]
["GO:0032481","positive regulation of type I interferon production","4/267","74/18866",0.0208429621448976,0.0353591212115861,0.012665130538224,"CREBBP/EP300/CTNNB1/PTPN11",4]
["GO:0036465","synaptic vesicle recycling","4/267","74/18866",0.0208429621448976,0.0353591212115861,0.012665130538224,"TOR1A/CDK5/SNCG/LRRK2",4]
["GO:0043507","positive regulation of JUN kinase activity","4/267","74/18866",0.0208429621448976,0.0353591212115861,0.012665130538224,"PTK2B/DVL3/AGER/TNF",4]
["GO:0002070","epithelial cell maturation","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"XBP1/HIF1A",2]
["GO:0002295","T-helper cell lineage commitment","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"IL6/MTOR",2]
["GO:0006206","pyrimidine nucleobase metabolic process","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"MAPK1/MTOR",2]
["GO:0006555","methionine metabolic process","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"MTR/MTHFR",2]
["GO:0010225","response to UV-C","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"BRCA2/TP53",2]
["GO:0010919","regulation of inositol phosphate biosynthetic process","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"POU1F1/PTK2B",2]
["GO:0010934","macrophage cytokine production","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"SIRT1/TGFB1",2]
["GO:0015812","gamma-aminobutyric acid transport","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"P2RX7/NF1",2]
["GO:0032604","granulocyte macrophage colony-stimulating factor production","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"IL1B/IL18",2]
["GO:0034374","low-density lipoprotein particle remodeling","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"APOB/APOE",2]
["GO:0034380","high-density lipoprotein particle assembly","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"PRKACA/APOE",2]
["GO:0035067","negative regulation of histone acetylation","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"BRCA1/SIRT1",2]
["GO:0042487","regulation of odontogenesis of dentin-containing tooth","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"NGFR/FGF8",2]
["GO:0044065","regulation of respiratory system process","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"FTO/MECP2",2]
["GO:0045838","positive regulation of membrane potential","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"AKT1/VCP",2]
["GO:0046325","negative regulation of glucose import","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"LEP/TNF",2]
["GO:0048012","hepatocyte growth factor receptor signaling pathway","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"STMN1/RAC1",2]
["GO:0048311","mitochondrion distribution","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"MAPT/LRRK2",2]
["GO:0048820","hair follicle maturation","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"CTNNB1/NF1",2]
["GO:0072109","glomerular mesangium development","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"PDGFRB/IL6R",2]
["GO:0097091","synaptic vesicle clustering","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"CTNNB1/PTEN",2]
["GO:0099170","postsynaptic modulation of chemical synaptic transmission","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"DRD2/DCC",2]
["GO:1900451","positive regulation of glutamate receptor signaling pathway","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"CCL2/IFNG",2]
["GO:1902166","negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"SIRT1/BCL2",2]
["GO:1902969","mitotic DNA replication","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"FGFR1/BRCA2",2]
["GO:1903541","regulation of exosomal secretion","2/267","16/18866",0.0210115186530695,0.0353591212115861,0.012665130538224,"IFNG/PRKN",2]
["GO:0043487","regulation of RNA stability","7/267","195/18866",0.0212837264386006,0.0358051368288183,0.0128248869411201,"TNFRSF1B/FUS/FTO/AKT1/GDNF/LIN28B/MTOR",7]
["GO:0044058","regulation of digestive system process","3/267","42/18866",0.0214401663335791,0.0360318917884755,0.0129061073183762,"TAC1/OXT/LEP",3]
["GO:0090279","regulation of calcium ion import","3/267","42/18866",0.0214401663335791,0.0360318917884755,0.0129061073183762,"CCL2/PDGFRB/CTNNB1",3]
["GO:1902622","regulation of neutrophil migration","3/267","42/18866",0.0214401663335791,0.0360318917884755,0.0129061073183762,"RAC1/CXCL8/DPP4",3]
["GO:0006814","sodium ion transport","8/267","241/18866",0.0217693920827626,0.0365287335237238,0.0130840689084311,"DLG1/P2RX7/AKT1/SLC6A3/DRD2/NOS3/PRKCE/DMD",8]
["GO:0006695","cholesterol biosynthetic process","4/267","75/18866",0.0217796995193523,0.0365287335237238,0.0130840689084311,"APOB/APOE/SOD1/LBR",4]
["GO:0015909","long-chain fatty acid transport","4/267","75/18866",0.0217796995193523,0.0365287335237238,0.0130840689084311,"APOE/AKT1/DRD2/ACE",4]
["GO:0035924","cellular response to vascular endothelial growth factor stimulus","4/267","75/18866",0.0217796995193523,0.0365287335237238,0.0130840689084311,"VEGFA/PDGFRB/AKT1/DLL1",4]
["GO:1900006","positive regulation of dendrite development","4/267","75/18866",0.0217796995193523,0.0365287335237238,0.0130840689084311,"IL2/APOE/ALK/MTOR",4]
["GO:1902653","secondary alcohol biosynthetic process","4/267","75/18866",0.0217796995193523,0.0365287335237238,0.0130840689084311,"APOB/APOE/SOD1/LBR",4]
["GO:0065004","protein-DNA complex assembly","8/267","243/18866",0.0227353702816426,0.0381167710171268,0.0136528811827292,"ATRX/ESR1/SMARCB1/TBP/CREB1/TP53/POGZ/TCF4",8]
["GO:0014743","regulation of muscle hypertrophy","4/267","76/18866",0.0227418107069939,0.0381167710171268,0.0136528811827292,"IGF1/TNFRSF1B/TNFRSF1A/MTOR",4]
["GO:0017158","regulation of calcium ion-dependent exocytosis","3/267","43/18866",0.0228128466837177,0.0381973653560706,0.0136817489200595,"REST/CDK5/ATP2A2",3]
["GO:0046688","response to copper ion","3/267","43/18866",0.0228128466837177,0.0381973653560706,0.0136817489200595,"IL1A/CYP1A2/SOD1",3]
["GO:0060119","inner ear receptor cell development","3/267","43/18866",0.0228128466837177,0.0381973653560706,0.0136817489200595,"FGFR1/SOD1/FZD2",3]
["GO:0009062","fatty acid catabolic process","5/267","114/18866",0.0230788155171421,0.0386167982161831,0.0138319837602739,"CNR1/AKT1/LEP/ADIPOQ/MTOR",5]
["GO:0030004","cellular monovalent inorganic cation homeostasis","5/267","114/18866",0.0230788155171421,0.0386167982161831,0.0138319837602739,"GRN/MAPK1/MAPK3/BCL2/LRRK2",5]
["GO:0000097","sulfur amino acid biosynthetic process","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"MTR/MTHFR",2]
["GO:0006474","N-terminal protein amino acid acetylation","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"CREBBP/EP300",2]
["GO:0010566","regulation of ketone biosynthetic process","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"REST/PPARGC1A",2]
["GO:0014067","negative regulation of phosphatidylinositol 3-kinase signaling","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"TSC2/PTEN",2]
["GO:0021514","ventral spinal cord interneuron differentiation","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"PAX6/GLI2",2]
["GO:0030889","negative regulation of B cell proliferation","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"IL10/PAWR",2]
["GO:0030949","positive regulation of vascular endothelial growth factor receptor signaling pathway","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"HIF1A/IL1B",2]
["GO:0031000","response to caffeine","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"PPARGC1A/HDAC2",2]
["GO:0033262","regulation of nuclear cell cycle DNA replication","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"FGFR1/ATRX",2]
["GO:0035020","regulation of Rac protein signal transduction","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"KRAS/NF1",2]
["GO:0036166","phenotypic switching","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"SOD2/DNMT1",2]
["GO:0042448","progesterone metabolic process","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"PPARGC1A/SRD5A1",2]
["GO:0042790","nucleolar large rRNA transcription by RNA polymerase I","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"SMARCB1/MTOR",2]
["GO:0045722","positive regulation of gluconeogenesis","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"SIRT1/PPARGC1A",2]
["GO:0045986","negative regulation of smooth muscle contraction","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"PTGS2/SOD1",2]
["GO:0048535","lymph node development","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"TGFB1/FADD",2]
["GO:0050665","hydrogen peroxide biosynthetic process","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"CYP1A2/SOD1",2]
["GO:0071850","mitotic cell cycle arrest","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"DUSP1/TP53",2]
["GO:0090336","positive regulation of brown fat cell differentiation","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"PTGS2/INS",2]
["GO:1900242","regulation of synaptic vesicle endocytosis","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"TOR1A/LRRK2",2]
["GO:1904355","positive regulation of telomere capping","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"MAPK1/MAPK3",2]
["GO:1904948","midbrain dopaminergic neuron differentiation","2/267","17/18866",0.0235936532741536,0.0391893249493842,0.0140370546320646,"SFRP1/CTNNB1",2]
["GO:0046785","microtubule polymerization","4/267","77/18866",0.0237294408089727,0.0394017618753577,0.014113146494826,"STMN1/RAC1/MECP2/MAPT",4]
["GO:0001913","T cell mediated cytotoxicity","3/267","44/18866",0.0242322955268994,0.0401432818731947,0.0143787483324144,"P2RX7/FADD/AGER",3]
["GO:0035307","positive regulation of protein dephosphorylation","3/267","44/18866",0.0242322955268994,0.0401432818731947,0.0143787483324144,"TGFB1/PDGFRB/MTOR",3]
["GO:0045005","DNA-dependent DNA replication maintenance of fidelity","3/267","44/18866",0.0242322955268994,0.0401432818731947,0.0143787483324144,"ATRX/TIMELESS/BRCA2",3]
["GO:0045684","positive regulation of epidermis development","3/267","44/18866",0.0242322955268994,0.0401432818731947,0.0143787483324144,"VDR/PTCH1/TNF",3]
["GO:0060999","positive regulation of dendritic spine development","3/267","44/18866",0.0242322955268994,0.0401432818731947,0.0143787483324144,"IL2/APOE/MTOR",3]
["GO:0097178","ruffle assembly","3/267","44/18866",0.0242322955268994,0.0401432818731947,0.0143787483324144,"PDGFRB/RAC1/INPPL1",3]
["GO:1903539","protein localization to postsynaptic membrane","3/267","44/18866",0.0242322955268994,0.0401432818731947,0.0143787483324144,"DLG1/ADAM10/GPC6",3]
["GO:0030203","glycosaminoglycan metabolic process","6/267","158/18866",0.0251265278278424,0.0416108634973191,0.0149044150404134,"TGFB1/PDGFRB/IL1B/IDUA/AKT1/GPC6",6]
["GO:0031109","microtubule polymerization or depolymerization","5/267","117/18866",0.0254695539644591,0.0421649479259099,0.0151028801429624,"HDAC6/STMN1/RAC1/MECP2/MAPT",5]
["GO:0003197","endocardial cushion development","3/267","45/18866",0.0256984797183947,0.0424454215130483,0.0152033417628193,"ERBB3/FGF8/NOS3",3]
["GO:0043114","regulation of vascular permeability","3/267","45/18866",0.0256984797183947,0.0424454215130483,0.0152033417628193,"TGFB1/VEGFA/APOE",3]
["GO:0055026","negative regulation of cardiac muscle tissue development","3/267","45/18866",0.0256984797183947,0.0424454215130483,0.0152033417628193,"FGF8/PTEN/DLL1",3]
["GO:0060412","ventricular septum morphogenesis","3/267","45/18866",0.0256984797183947,0.0424454215130483,0.0152033417628193,"FGFR2/NOS3/FZD2",3]
["GO:0070266","necroptotic process","3/267","45/18866",0.0256984797183947,0.0424454215130483,0.0152033417628193,"TP53/FADD/TNF",3]
["GO:0070316","regulation of G0 to G1 transition","3/267","45/18866",0.0256984797183947,0.0424454215130483,0.0152033417628193,"BRCA1/L3MBTL2/EHMT1",3]
["GO:0098815","modulation of excitatory postsynaptic potential","3/267","45/18866",0.0256984797183947,0.0424454215130483,0.0152033417628193,"PTK2B/PTEN/LRRK2",3]
["GO:0009205","purine ribonucleoside triphosphate metabolic process","4/267","79/18866",0.0257817891724534,0.0425548672191933,0.0152425436464544,"TGFB1/PPARGC1A/VCP/LRRK2",4]
["GO:0030104","water homeostasis","4/267","79/18866",0.0257817891724534,0.0425548672191933,0.0152425436464544,"PRKACA/PRKAR1A/SRF/STMN1",4]
["GO:0010839","negative regulation of keratinocyte proliferation","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"FGFR2/VDR",2]
["GO:0010885","regulation of cholesterol storage","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"APOB/LPL",2]
["GO:0021756","striatum development","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"DRD2/LRRK2",2]
["GO:0032780","negative regulation of ATPase activity","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"SIRT1/TP53",2]
["GO:0033194","response to hydroperoxide","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"CD38/GPX1",2]
["GO:0034199","activation of protein kinase A activity","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"PRKACA/PRKAR1A",2]
["GO:0034375","high-density lipoprotein particle remodeling","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"APOE/ALB",2]
["GO:0035313","wound healing, spreading of epidermal cells","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"PTEN/MTOR",2]
["GO:0048557","embryonic digestive tract morphogenesis","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"FGFR2/SHH",2]
["GO:0060977","coronary vasculature morphogenesis","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"VEGFA/PDGFRB",2]
["GO:0061298","retina vasculature development in camera-type eye","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"HIF1A/PDGFRB",2]
["GO:0071371","cellular response to gonadotropin stimulus","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"GCLC/PPARGC1A",2]
["GO:0072079","nephron tubule formation","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"CTNNB1/GDNF",2]
["GO:0072189","ureter development","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"SHH/RET",2]
["GO:0090036","regulation of protein kinase C signaling","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"VEGFA/MC1R",2]
["GO:0090190","positive regulation of branching involved in ureteric bud morphogenesis","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"VEGFA/GDNF",2]
["GO:1902165","regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"SIRT1/BCL2",2]
["GO:1902683","regulation of receptor localization to synapse","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"ADAM10/GPC6",2]
["GO:1990000","amyloid fibril formation","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"APOE/MAPT",2]
["GO:2000303","regulation of ceramide biosynthetic process","2/267","18/18866",0.0262985999111432,0.0430974229006135,0.0154368793169684,"TNFRSF1A/TNF",2]
["GO:0006661","phosphatidylinositol biosynthetic process","5/267","118/18866",0.0263003900617203,0.0430974229006135,0.0154368793169684,"HTR2A/PIK3CA/PIK3R1/INPPL1/PTEN",5]
["GO:0007052","mitotic spindle organization","5/267","118/18866",0.0263003900617203,0.0430974229006135,0.0154368793169684,"SMC3/STMN1/PLK2/VCP/MECP2",5]
["GO:0051168","nuclear export","7/267","204/18866",0.0264053158938208,0.0432551647827583,0.0154933801987849,"PRKACA/GSK3B/TGFB1/IL1B/TP53/CDK5/PTPN11",7]
["GO:0032204","regulation of telomere maintenance","4/267","80/18866",0.0268467488328786,0.0439638625524968,0.0157472255845957,"ATRX/MAPK1/MAPK3/CTNNB1",4]
["GO:0010761","fibroblast migration","3/267","46/18866",0.0272113359686139,0.0445025222703207,0.0159401657767769,"TGFB1/AKT1/PRKCE",3]
["GO:0032007","negative regulation of TOR signaling","3/267","46/18866",0.0272113359686139,0.0445025222703207,0.0159401657767769,"SIRT1/HIF1A/TSC2",3]
["GO:0043330","response to exogenous dsRNA","3/267","46/18866",0.0272113359686139,0.0445025222703207,0.0159401657767769,"MAPK1/MAPK3/IFNA1",3]
["GO:0045023","G0 to G1 transition","3/267","46/18866",0.0272113359686139,0.0445025222703207,0.0159401657767769,"BRCA1/L3MBTL2/EHMT1",3]
["GO:0051258","protein polymerization","9/267","300/18866",0.0275166598804215,0.0449871259931056,0.0161137438861325,"DLG1/STMN1/PTK2B/RAC1/MECP2/PRKCE/PRKN/MAPT/MTOR",9]
["GO:0050852","T cell receptor signaling pathway","7/267","206/18866",0.0276482785911396,0.0451875139134403,0.0161855199677306,"MAPK1/PIK3CA/PIK3R1/PAWR/HLA-DQB1/HLA-DRB1/HLA-DQA1",7]
["GO:0016126","sterol biosynthetic process","4/267","81/18866",0.0279377103413827,0.0456306796645482,0.0163442555894183,"APOB/APOE/SOD1/LBR",4]
["GO:0050829","defense response to Gram-negative bacterium","4/267","81/18866",0.0279377103413827,0.0456306796645482,0.0163442555894183,"NOS2/IL6/IL6R/F2",4]
["GO:0014003","oligodendrocyte development","3/267","47/18866",0.0287707719973031,0.0469299132906026,0.0168096224568572,"SHH/PTEN/MED12",3]
["GO:0032369","negative regulation of lipid transport","3/267","47/18866",0.0287707719973031,0.0469299132906026,0.0168096224568572,"AKT1/SHH/PTPN11",3]
["GO:0045933","positive regulation of muscle contraction","3/267","47/18866",0.0287707719973031,0.0469299132906026,0.0168096224568572,"PTGS2/OXT/SRF",3]
["GO:0046638","positive regulation of alpha-beta T cell differentiation","3/267","47/18866",0.0287707719973031,0.0469299132906026,0.0168096224568572,"IFNG/IL18/SHH",3]
["GO:0072522","purine-containing compound biosynthetic process","7/267","208/18866",0.0289304459892402,0.0471749565069485,0.016897393425597,"NOS2/ACSL4/ADA2/TGFB1/PPARGC1A/NOS3/VCP",7]
["GO:0022617","extracellular matrix disassembly","4/267","82/18866",0.0290547704028759,0.0472411004616833,0.0169210852423709,"TGFB1/IL6/ADAM10/DPP4",4]
["GO:0045652","regulation of megakaryocyte differentiation","4/267","82/18866",0.0290547704028759,0.0472411004616833,0.0169210852423709,"EP300/GATA1/KMT2A/KMT2D",4]
["GO:0002922","positive regulation of humoral immune response","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"IL1B/TNF",2]
["GO:0007625","grooming behavior","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"OXT/DRD2",2]
["GO:0010663","positive regulation of striated muscle cell apoptotic process","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"TP53/PTEN",2]
["GO:0010666","positive regulation of cardiac muscle cell apoptotic process","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"TP53/PTEN",2]
["GO:0031643","positive regulation of myelination","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"TNFRSF1B/S100B",2]
["GO:0043373","CD4-positive, alpha-beta T cell lineage commitment","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"IL6/MTOR",2]
["GO:0045683","negative regulation of epidermis development","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"NGFR/DLL1",2]
["GO:0051546","keratinocyte migration","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"PTEN/MTOR",2]
["GO:0072074","kidney mesenchyme development","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"PDGFRB/SHH",2]
["GO:0090153","regulation of sphingolipid biosynthetic process","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"TNFRSF1A/TNF",2]
["GO:1902170","cellular response to reactive nitrogen species","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"PPARGC1A/MTR",2]
["GO:1905038","regulation of membrane lipid metabolic process","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"TNFRSF1A/TNF",2]
["GO:1990182","exosomal secretion","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"IFNG/PRKN",2]
["GO:2000104","negative regulation of DNA-dependent DNA replication","2/267","19/18866",0.029122392794124,0.0472411004616833,0.0169210852423709,"TIMELESS/BRCA2",2]
["GO:1990266","neutrophil migration","5/267","122/18866",0.0297960303900536,0.0483181486643513,0.0173068684749666,"CCL2/IL1B/RAC1/CXCL8/DPP4",5]
["GO:0002088","lens development in camera-type eye","4/267","83/18866",0.0301980162643625,0.0489314839943736,0.0175265564013705,"PAX6/DLG1/ATF4/CTNNB1",4]
["GO:0071277","cellular response to calcium ion","4/267","83/18866",0.0301980162643625,0.0489314839943736,0.0175265564013705,"FUS/BRAF/FOS/JUN",4]
["GO:0016482","cytosolic transport","6/267","165/18866",0.0302036518467173,0.0489314839943736,0.0175265564013705,"MAPK1/MAPK3/MAP2K2/MAP2K1/PRKN/LRRK2",6]
["GO:0008206","bile acid metabolic process","3/267","48/18866",0.0303766676572207,0.0491161598486085,0.0175927046460383,"SIRT1/CYP27A1/LEP",3]
["GO:0009409","response to cold","3/267","48/18866",0.0303766676572207,0.0491161598486085,0.0175927046460383,"PPARGC1A/FOS/LPL",3]
["GO:0043370","regulation of CD4-positive, alpha-beta T cell differentiation","3/267","48/18866",0.0303766676572207,0.0491161598486085,0.0175927046460383,"IL2/IFNG/IL18",3]
["GO:0062237","protein localization to postsynapse","3/267","48/18866",0.0303766676572207,0.0491161598486085,0.0175927046460383,"DLG1/ADAM10/GPC6",3]
["GO:0070169","positive regulation of biomineral tissue development","3/267","48/18866",0.0303766676572207,0.0491161598486085,0.0175927046460383,"P2RX7/TGFB1/ATF4",3]
["GO:0110151","positive regulation of biomineralization","3/267","48/18866",0.0303766676572207,0.0491161598486085,0.0175927046460383,"P2RX7/TGFB1/ATF4",3]
["GO:0010951","negative regulation of endopeptidase activity","8/267","258/18866",0.0309605329838555,0.0500440081542216,0.0179250466134741,"NGFR/PTGS2/VEGFA/NGF/AKT1/SERPINA3/TNF/GPX1",8]
["GO:0008652","cellular amino acid biosynthetic process","4/267","84/18866",0.0313675257998752,0.0506854551193453,0.0181548037247447,"FOLH1/MTR/GLUL/MTHFR",4]
["GO:0051701","interaction with host","7/267","212/18866",0.0316142574202339,0.0510676115494105,0.0182916866818701,"HTR2A/NCAM1/CTNNB1/CXCL8/BCL2L1/HLA-DRB1/DPP4",7]
["GO:0010633","negative regulation of epithelial cell migration","5/267","124/18866",0.0316484986418078,0.0511063886541224,0.01830557608512,"TGFB1/APOE/MECP2/PTEN/TNF",5]
["GO:0018198","peptidyl-cysteine modification","3/267","49/18866",0.0320288760279727,0.0514069804963712,0.0184132437756722,"NOS2/ACE/DMD",3]
["GO:0001832","blastocyst growth","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"IGF1/BRCA2",2]
["GO:0002320","lymphoid progenitor cell differentiation","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"SHH/BCL2",2]
["GO:0002827","positive regulation of T-helper 1 type immune response","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"IL1B/IL18",2]
["GO:0003323","type B pancreatic cell development","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"GSK3B/DLL1",2]
["GO:0006346","DNA methylation-dependent heterochromatin assembly","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"SIRT1/DNMT1",2]
["GO:0006525","arginine metabolic process","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"NOS2/NOS3",2]
["GO:0007252","I-kappaB phosphorylation","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"AKT1/TNF",2]
["GO:0010002","cardioblast differentiation","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"REST/SRF",2]
["GO:0010878","cholesterol storage","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"APOB/LPL",2]
["GO:0023019","signal transduction involved in regulation of gene expression","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"PAX6/FGF8",2]
["GO:0039692","single stranded viral RNA replication via double stranded DNA intermediate","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"SMARCB1/CXCL8",2]
["GO:0043931","ossification involved in bone maturation","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"IGF1/LEP",2]
["GO:0045019","negative regulation of nitric oxide biosynthetic process","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"TSPO/IL10",2]
["GO:0046931","pore complex assembly","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"P2RX7/ADAM10",2]
["GO:0060353","regulation of cell adhesion molecule production","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"IL1B/CXCL8",2]
["GO:0071636","positive regulation of transforming growth factor beta production","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"PTGS2/CREB1",2]
["GO:0097062","dendritic spine maintenance","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"APOE/INS",2]
["GO:0097734","extracellular exosome biogenesis","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"IFNG/PRKN",2]
["GO:1902004","positive regulation of amyloid-beta formation","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"IFNG/TNF",2]
["GO:1904406","negative regulation of nitric oxide metabolic process","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"TSPO/IL10",2]
["GO:2001169","regulation of ATP biosynthetic process","2/267","20/18866",0.0320611530674344,0.0514069804963712,0.0184132437756722,"PPARGC1A/VCP",2]
["GO:0009199","ribonucleoside triphosphate metabolic process","4/267","85/18866",0.0325633675996845,0.052178720932357,0.0186896701411607,"TGFB1/PPARGC1A/VCP/LRRK2",4]
["GO:0030101","natural killer cell activation","4/267","85/18866",0.0325633675996845,0.052178720932357,0.0186896701411607,"IL2/IL18/LEP/IFNA1",4]
["GO:0007368","determination of left/right symmetry","5/267","125/18866",0.0326011849918484,0.0522058103477547,0.0186993731815774,"HIF1A/FGF8/SRF/SHH/DLL1",5]
["GO:0032479","regulation of type I interferon production","5/267","125/18866",0.0326011849918484,0.0522058103477547,0.0186993731815774,"CREBBP/EP300/IL10/CTNNB1/PTPN11",5]
["GO:0052126","movement in host environment","6/267","169/18866",0.0333863161203429,0.0534459366427933,0.019143568650027,"HTR2A/NCAM1/CTNNB1/CXCL8/HLA-DRB1/DPP4",6]
["GO:0001961","positive regulation of cytokine-mediated signaling pathway","3/267","50/18866",0.0337272244806797,0.0538535439181431,0.0192895677352346,"HIF1A/FADD/PRKN",3]
["GO:0003044","regulation of systemic arterial blood pressure mediated by a chemical signal","3/267","50/18866",0.0337272244806797,0.0538535439181431,0.0192895677352346,"SOD2/ACE/NOS3",3]
["GO:0009066","aspartate family amino acid metabolic process","3/267","50/18866",0.0337272244806797,0.0538535439181431,0.0192895677352346,"MTR/ATF4/MTHFR",3]
["GO:0019674","NAD metabolic process","3/267","50/18866",0.0337272244806797,0.0538535439181431,0.0192895677352346,"CD38/LDHA/TP53",3]
["GO:0030195","negative regulation of blood coagulation","3/267","50/18866",0.0337272244806797,0.0538535439181431,0.0192895677352346,"APOE/NOS3/F2",3]
["GO:0045540","regulation of cholesterol biosynthetic process","3/267","50/18866",0.0337272244806797,0.0538535439181431,0.0192895677352346,"APOB/APOE/SOD1",3]
["GO:0106118","regulation of sterol biosynthetic process","3/267","50/18866",0.0337272244806797,0.0538535439181431,0.0192895677352346,"APOB/APOE/SOD1",3]
["GO:1902743","regulation of lamellipodium organization","3/267","50/18866",0.0337272244806797,0.0538535439181431,0.0192895677352346,"HDAC4/RAC1/MTOR",3]
["GO:0007193","adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway","4/267","86/18866",0.033785601063547,0.0539122742442601,0.0193106040964715,"OPRM1/GNAL/DRD2/EDNRA",4]
["GO:0035023","regulation of Rho protein signal transduction","4/267","86/18866",0.033785601063547,0.0539122742442601,0.0193106040964715,"PDGFRB/STMN1/APOE/RAC1",4]
["GO:0043687","post-translational protein modification","10/267","363/18866",0.0345015223437474,0.05503709299116,0.0197134980534814,"APOB/FOLH1/HIF1A/APOE/MEN1/IL6/ADAM10/ALB/FBN1/PENK",10]
["GO:0032606","type I interferon production","5/267","127/18866",0.0345598324634297,0.0550949053288329,0.0197342056044119,"CREBBP/EP300/IL10/CTNNB1/PTPN11",5]
["GO:0051053","negative regulation of DNA metabolic process","5/267","127/18866",0.0345598324634297,0.0550949053288329,0.0197342056044119,"KMT2A/DUSP1/MEN1/TP53/ADIPOQ",5]
["GO:0009144","purine nucleoside triphosphate metabolic process","4/267","87/18866",0.0350342764977627,0.0554777399004389,0.0198713314621198,"TGFB1/PPARGC1A/VCP/LRRK2",4]
["GO:0030512","negative regulation of transforming growth factor beta receptor signaling pathway","4/267","87/18866",0.0350342764977627,0.0554777399004389,0.0198713314621198,"SIRT1/TGFB1/TP53/FBN1",4]
["GO:0090049","regulation of cell migration involved in sprouting angiogenesis","4/267","87/18866",0.0350342764977627,0.0554777399004389,0.0198713314621198,"HDAC9/PTGS2/VEGFA/PLK2",4]
["GO:0097581","lamellipodium organization","4/267","87/18866",0.0350342764977627,0.0554777399004389,0.0198713314621198,"HDAC4/RAC1/CDH13/MTOR",4]
["GO:0001502","cartilage condensation","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"COL11A1/COL2A1",2]
["GO:0002693","positive regulation of cellular extravasation","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"FADD/AGER",2]
["GO:0009067","aspartate family amino acid biosynthetic process","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"MTR/MTHFR",2]
["GO:0021854","hypothalamus development","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"BAX/SRD5A1",2]
["GO:0032516","positive regulation of phosphoprotein phosphatase activity","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"PDGFRB/MTOR",2]
["GO:0033630","positive regulation of cell adhesion mediated by integrin","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"LIF/RET",2]
["GO:0035357","peroxisome proliferator activated receptor signaling pathway","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"SIRT1/LEP",2]
["GO:0045717","negative regulation of fatty acid biosynthetic process","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"BRCA1/SIRT1",2]
["GO:0046823","negative regulation of nucleocytoplasmic transport","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"CDK5/NF1",2]
["GO:0051957","positive regulation of amino acid transport","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"P2RX7/CCK",2]
["GO:0060117","auditory receptor cell development","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"FGFR1/SOD1",2]
["GO:0060713","labyrinthine layer morphogenesis","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"FGFR2/IL10",2]
["GO:0060716","labyrinthine layer blood vessel development","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"MAPK1/AKT1",2]
["GO:0061213","positive regulation of mesonephros development","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"VEGFA/GDNF",2]
["GO:0071498","cellular response to fluid shear stress","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"PTGS2/PTK2B",2]
["GO:0072574","hepatocyte proliferation","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"XBP1/IL6",2]
["GO:0072575","epithelial cell proliferation involved in liver morphogenesis","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"XBP1/IL6",2]
["GO:0080182","histone H3-K4 trimethylation","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"KMT2A/KMT2D",2]
["GO:0090280","positive regulation of calcium ion import","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"CCL2/PDGFRB",2]
["GO:0140131","positive regulation of lymphocyte chemotaxis","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"PTK2B/ADAM10",2]
["GO:1900543","negative regulation of purine nucleotide metabolic process","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"HDAC4/PPARGC1A",2]
["GO:1903055","positive regulation of extracellular matrix organization","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"TGFB1/IL6",2]
["GO:2000380","regulation of mesoderm development","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"FGFR1/SHH",2]
["GO:2000678","negative regulation of transcription regulatory region DNA binding","2/267","21/18866",0.0351110871390721,0.0554777399004389,0.0198713314621198,"GATA1/PER2",2]
["GO:0002204","somatic recombination of immunoglobulin genes involved in immune response","3/267","51/18866",0.0354715157141279,0.0558880649923131,0.0200183040302613,"TGFB1/IL2/IL10",3]
["GO:0002208","somatic diversification of immunoglobulins involved in immune response","3/267","51/18866",0.0354715157141279,0.0558880649923131,0.0200183040302613,"TGFB1/IL2/IL10",3]
["GO:0021545","cranial nerve development","3/267","51/18866",0.0354715157141279,0.0558880649923131,0.0200183040302613,"ERBB3/CTNNB1/CHD7",3]
["GO:0038084","vascular endothelial growth factor signaling pathway","3/267","51/18866",0.0354715157141279,0.0558880649923131,0.0200183040302613,"VEGFA/PDGFRB/DLL1",3]
["GO:0045190","isotype switching","3/267","51/18866",0.0354715157141279,0.0558880649923131,0.0200183040302613,"TGFB1/IL2/IL10",3]
["GO:0048255","mRNA stabilization","3/267","51/18866",0.0354715157141279,0.0558880649923131,0.0200183040302613,"FUS/GDNF/MTOR",3]
["GO:0060976","coronary vasculature development","3/267","51/18866",0.0354715157141279,0.0558880649923131,0.0200183040302613,"SRF/VEGFA/PDGFRB",3]
["GO:0090102","cochlea development","3/267","51/18866",0.0354715157141279,0.0558880649923131,0.0200183040302613,"GLI2/ADAM10/FZD2",3]
["GO:1900047","negative regulation of hemostasis","3/267","51/18866",0.0354715157141279,0.0558880649923131,0.0200183040302613,"APOE/NOS3/F2",3]
["GO:0009913","epidermal cell differentiation","10/267","365/18866",0.0356099884582814,0.0560885401805044,0.0200901113699552,"PAX6/FGFR1/VDR/FLNB/SOD1/CTNNB1/MAP2K1/PTCH1/HDAC2/DLL1",10]
["GO:0000910","cytokinesis","6/267","172/18866",0.0359109134689092,0.0565268571722142,0.020247110235507,"STMN1/BRCA2/PLK2/DRD2/PRKCE/BCL2L1",6]
["GO:0006022","aminoglycan metabolic process","6/267","172/18866",0.0359109134689092,0.0565268571722142,0.020247110235507,"TGFB1/PDGFRB/IL1B/IDUA/AKT1/GPC6",6]
["GO:0070098","chemokine-mediated signaling pathway","4/267","88/18866",0.0363094352158182,0.0571361519169809,0.020465350882172,"HIF1A/CCL2/PTK2B/CXCL8",4]
["GO:0001912","positive regulation of leukocyte mediated cytotoxicity","3/267","52/18866",0.0372615287630483,0.0585052871427359,0.0209557555009663,"NOS2/P2RX7/FADD",3]
["GO:0003179","heart valve morphogenesis","3/267","52/18866",0.0372615287630483,0.0585052871427359,0.0209557555009663,"TGFB1/NOS3/MTOR",3]
["GO:0006301","postreplication repair","3/267","52/18866",0.0372615287630483,0.0585052871427359,0.0209557555009663,"BRCA1/REV1/VCP",3]
["GO:0032330","regulation of chondrocyte differentiation","3/267","52/18866",0.0372615287630483,0.0585052871427359,0.0209557555009663,"GLI2/CTNNB1/PTPN11",3]
["GO:0046580","negative regulation of Ras protein signal transduction","3/267","52/18866",0.0372615287630483,0.0585052871427359,0.0209557555009663,"MFN2/STMN1/NF1",3]
["GO:0051445","regulation of meiotic cell cycle","3/267","52/18866",0.0372615287630483,0.0585052871427359,0.0209557555009663,"PRKAR1A/DUSP1/LIF",3]
["GO:0072132","mesenchyme morphogenesis","3/267","52/18866",0.0372615287630483,0.0585052871427359,0.0209557555009663,"FGFR1/FGF8/NOS3",3]
["GO:0007163","establishment or maintenance of cell polarity","7/267","220/18866",0.037471851529145,0.0588170244215721,0.0210674153271951,"PAX6/DLG1/GSK3B/PTK2B/RAC1/PRKCI/SHH",7]
["GO:0043537","negative regulation of blood vessel endothelial cell migration","4/267","89/18866",0.0376111096424014,0.0589799844360899,0.0211257852692542,"TGFB1/APOE/MECP2/TNF",4]
["GO:1901019","regulation of calcium ion transmembrane transporter activity","4/267","89/18866",0.0376111096424014,0.0589799844360899,0.0211257852692542,"PRKACA/DRD2/CDK5/DMD",4]
["GO:1903845","negative regulation of cellular response to transforming growth factor beta stimulus","4/267","89/18866",0.0376111096424014,0.0589799844360899,0.0211257852692542,"SIRT1/TGFB1/TP53/FBN1",4]
["GO:0002089","lens morphogenesis in camera-type eye","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"ATF4/CTNNB1",2]
["GO:0007063","regulation of sister chromatid cohesion","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"ATRX/CTNNB1",2]
["GO:0007398","ectoderm development","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"SHH/CTNNB1",2]
["GO:0032069","regulation of nuclease activity","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"SIRT1/AKT1",2]
["GO:0035809","regulation of urine volume","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"OXT/DRD2",2]
["GO:0035970","peptidyl-threonine dephosphorylation","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"DUSP1/DUSP6",2]
["GO:0036120","cellular response to platelet-derived growth factor stimulus","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"PDGFRB/CREB1",2]
["GO:0044342","type B pancreatic cell proliferation","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"SFRP1/MEN1",2]
["GO:0045061","thymic T cell selection","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"SRF/SHH",2]
["GO:0045655","regulation of monocyte differentiation","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"JUN/HLA-DRB1",2]
["GO:0045980","negative regulation of nucleotide metabolic process","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"HDAC4/PPARGC1A",2]
["GO:0050765","negative regulation of phagocytosis","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"PTEN/ADIPOQ",2]
["GO:0050802","circadian sleep/wake cycle, sleep","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"SRD5A1/DRD2",2]
["GO:0060352","cell adhesion molecule production","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"IL1B/CXCL8",2]
["GO:0070987","error-free translesion synthesis","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"REV1/VCP",2]
["GO:0072576","liver morphogenesis","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"XBP1/IL6",2]
["GO:0090189","regulation of branching involved in ureteric bud morphogenesis","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"VEGFA/GDNF",2]
["GO:0140112","extracellular vesicle biogenesis","2/267","22/18866",0.0382684850591347,0.0596734996565458,0.0213741924834708,"IFNG/PRKN",2]
["GO:0000731","DNA synthesis involved in DNA repair","3/267","53/18866",0.039097019979152,0.0608704149535098,0.0218029103916036,"SIRT1/REV1/VCP",3]
["GO:0032210","regulation of telomere maintenance via telomerase","3/267","53/18866",0.039097019979152,0.0608704149535098,0.0218029103916036,"MAPK1/MAPK3/CTNNB1",3]
["GO:0043949","regulation of cAMP-mediated signaling","3/267","53/18866",0.039097019979152,0.0608704149535098,0.0218029103916036,"PRKAR1A/OPRM1/PDE11A",3]
["GO:0061756","leukocyte adhesion to vascular endothelial cell","3/267","53/18866",0.039097019979152,0.0608704149535098,0.0218029103916036,"IL6/LEP/TNF",3]
["GO:0071320","cellular response to cAMP","3/267","53/18866",0.039097019979152,0.0608704149535098,0.0218029103916036,"SRD5A1/ADIPOQ/PENK",3]
["GO:0010466","negative regulation of peptidase activity","8/267","272/18866",0.0402972903086138,0.0627195668674903,0.0224652501097043,"NGFR/PTGS2/VEGFA/NGF/AKT1/SERPINA3/TNF/GPX1",8]
["GO:0090101","negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway","5/267","133/18866",0.0408665253959977,0.0635857155818687,0.0227754921676863,"SIRT1/SFRP1/TGFB1/TP53/FBN1",5]
["GO:0006754","ATP biosynthetic process","3/267","54/18866",0.0409777239855368,0.0637190208221068,0.0228232401945375,"TGFB1/PPARGC1A/VCP",3]
["GO:0010524","positive regulation of calcium ion transport into cytosol","3/267","54/18866",0.0409777239855368,0.0637190208221068,0.0228232401945375,"BAX/P2RX7/F2",3]
["GO:0000002","mitochondrial genome maintenance","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"PPARGC1A/TP53",2]
["GO:0001956","positive regulation of neurotransmitter secretion","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"CNR1/CDK5",2]
["GO:0006541","glutamine metabolic process","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"GLUL/MECP2",2]
["GO:0006582","melanin metabolic process","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"BCL2/MC1R",2]
["GO:0006590","thyroid hormone generation","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"TG/TPO",2]
["GO:0010288","response to lead ion","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"PTGS2/MAPT",2]
["GO:0016048","detection of temperature stimulus","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"NGFR/HTR2A",2]
["GO:0032799","low-density lipoprotein receptor particle metabolic process","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"APOE/ADIPOQ",2]
["GO:0034643","establishment of mitochondrion localization, microtubule-mediated","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"HIF1A/MAPT",2]
["GO:0036119","response to platelet-derived growth factor","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"PDGFRB/CREB1",2]
["GO:0043576","regulation of respiratory gaseous exchange","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"FTO/MECP2",2]
["GO:0045723","positive regulation of fatty acid biosynthetic process","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"PTGS2/IL1B",2]
["GO:0046599","regulation of centriole replication","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"BRCA1/PLK2",2]
["GO:0047497","mitochondrion transport along microtubule","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"HIF1A/MAPT",2]
["GO:0051457","maintenance of protein location in nucleus","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"SYNE1/CDK5",2]
["GO:0060479","lung cell differentiation","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"CREB1/CTNNB1",2]
["GO:0070584","mitochondrion morphogenesis","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"BAX/BCL2L1",2]
["GO:0071404","cellular response to low-density lipoprotein particle stimulus","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"CDH13/LPL",2]
["GO:0072243","metanephric nephron epithelium development","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"LIF/ADIPOQ",2]
["GO:0097150","neuronal stem cell population maintenance","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"REST/DLL1",2]
["GO:1901032","negative regulation of response to reactive oxygen species","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"IL10/LRRK2",2]
["GO:1903077","negative regulation of protein localization to plasma membrane","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"TGFB1/BCL2L1",2]
["GO:1903206","negative regulation of hydrogen peroxide-induced cell death","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"IL10/LRRK2",2]
["GO:1904996","positive regulation of leukocyte adhesion to vascular endothelial cell","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"IL6/TNF",2]
["GO:2000773","negative regulation of cellular senescence","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"SIRT1/PLK2",2]
["GO:2000810","regulation of bicellular tight junction assembly","2/267","23/18866",0.0415297189268065,0.0640586612917964,0.0229448945438903,"PRKACA/TNF",2]
["GO:0043087","regulation of GTPase activity","12/267","481/18866",0.0417832474643115,0.0644298192060863,0.0230778379902686,"GSK3B/TSC2/SFRP1/CCL2/PTK2B/SOD1/NTRK2/DVL3/JUN/LRRK2/NF1/MTOR",12]
["GO:0001706","endoderm formation","3/267","55/18866",0.0429033546050705,0.0660143141889421,0.0236453813880512,"COL11A1/DUSP1/CTNNB1",3]
["GO:0002720","positive regulation of cytokine production involved in immune response","3/267","55/18866",0.0429033546050705,0.0660143141889421,0.0236453813880512,"IL1B/IL6/IL18",3]
["GO:0045620","negative regulation of lymphocyte differentiation","3/267","55/18866",0.0429033546050705,0.0660143141889421,0.0236453813880512,"SFRP1/IL2/SHH",3]
["GO:0046164","alcohol catabolic process","3/267","55/18866",0.0429033546050705,0.0660143141889421,0.0236453813880512,"APOE/CYP27A1/PTEN",3]
["GO:0050819","negative regulation of coagulation","3/267","55/18866",0.0429033546050705,0.0660143141889421,0.0236453813880512,"APOE/NOS3/F2",3]
["GO:0050879","multicellular organismal movement","3/267","55/18866",0.0429033546050705,0.0660143141889421,0.0236453813880512,"ATP2A2/MTOR/DMD",3]
["GO:0050881","musculoskeletal movement","3/267","55/18866",0.0429033546050705,0.0660143141889421,0.0236453813880512,"ATP2A2/MTOR/DMD",3]
["GO:0050853","B cell receptor signaling pathway","5/267","135/18866",0.0431137374223332,0.0663175880929481,0.0237540097546921,"CD38/BAX/MAPK1/BCL2/PAX5",5]
["GO:0016064","immunoglobulin mediated immune response","7/267","227/18866",0.0431490757619686,0.0663515045517429,0.0237661581442253,"TGFB1/IL2/CRP/IL10/HLA-DQB1/HLA-DRB1/TNF",7]
["GO:0006898","receptor-mediated endocytosis","9/267","328/18866",0.0444799394857511,0.0683769513092226,0.0244916441490443,"APOB/VEGFA/APOE/RAC1/DRD2/ALB/CXCL8/DLL1/HP",9]
["GO:0016447","somatic recombination of immunoglobulin gene segments","3/267","56/18866",0.0448736057633422,0.0686919913998743,0.0246044869951377,"TGFB1/IL2/IL10",3]
["GO:0043113","receptor clustering","3/267","56/18866",0.0448736057633422,0.0686919913998743,0.0246044869951377,"DLG1/APOE/CDK5",3]
["GO:0002438","acute inflammatory response to antigenic stimulus","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"OPRM1/CNR1",2]
["GO:0010881","regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"PRKACA/DMD",2]
["GO:0021801","cerebral cortex radial glia guided migration","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"CDK5/CTNNB1",2]
["GO:0022030","telencephalon glial cell migration","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"CDK5/CTNNB1",2]
["GO:0032891","negative regulation of organic acid transport","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"AKT1/LEP",2]
["GO:0032925","regulation of activin receptor signaling pathway","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"MEN1/SHH",2]
["GO:0042430","indole-containing compound metabolic process","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"IDO1/SRD5A1",2]
["GO:0044550","secondary metabolite biosynthetic process","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"CYP1A2/MC1R",2]
["GO:0051004","regulation of lipoprotein lipase activity","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"HDAC9/LPL",2]
["GO:0060396","growth hormone receptor signaling pathway","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"PIK3R1/PRL",2]
["GO:0071294","cellular response to zinc ion","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"TSPO/CREB1",2]
["GO:0090103","cochlea morphogenesis","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"GLI2/FZD2",2]
["GO:0098743","cell aggregation","2/267","24/18866",0.0448912413254135,0.0686919913998743,0.0246044869951377,"COL11A1/COL2A1",2]
["GO:0090288","negative regulation of cellular response to growth factor stimulus","6/267","182/18866",0.0451982026262395,0.0691405103286807,0.0247651400483684,"NGFR/SIRT1/SFRP1/TGFB1/TP53/FBN1",6]
["GO:0019724","B cell mediated immunity","7/267","230/18866",0.0457435616597549,0.0699533241553312,0.0250562783138304,"TGFB1/IL2/CRP/IL10/HLA-DQB1/HLA-DRB1/TNF",7]
["GO:0032984","protein-containing complex disassembly","9/267","330/18866",0.0459105322835241,0.0701871670825585,0.0251400374995029,"GSK3B/HDAC6/SMARCB1/STMN1/DVL3/VCP/CTNNB1/FZD2/TNF",9]
["GO:0046330","positive regulation of JNK cascade","5/267","138/18866",0.0466215665538802,0.0712523666371361,0.0255215767161382,"PTK2B/IL1B/DVL3/AGER/TNF",5]
["GO:0006576","cellular biogenic amine metabolic process","3/267","57/18866",0.0468881523667576,0.0715940503875293,0.0256439629393598,"IDO1/MECP2/MAOA",3]
["GO:0060760","positive regulation of response to cytokine stimulus","3/267","57/18866",0.0468881523667576,0.0715940503875293,0.0256439629393598,"HIF1A/FADD/PRKN",3]
["GO:0097120","receptor localization to synapse","3/267","57/18866",0.0468881523667576,0.0715940503875293,0.0256439629393598,"DLG1/ADAM10/GPC6",3]
["GO:0071824","protein-DNA complex subunit organization","8/267","282/18866",0.0480105382976917,0.073285422720995,0.0262497882726281,"ATRX/ESR1/SMARCB1/TBP/CREB1/TP53/POGZ/TCF4",8]
["GO:0002092","positive regulation of receptor internalization","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"VEGFA/DRD2",2]
["GO:0015874","norepinephrine transport","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"OXT/SLC6A3",2]
["GO:0022410","circadian sleep/wake cycle process","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"SRD5A1/DRD2",2]
["GO:0045109","intermediate filament organization","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"GFAP/SHH",2]
["GO:0045992","negative regulation of embryonic development","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"PRKACA/CTNNB1",2]
["GO:0046639","negative regulation of alpha-beta T cell differentiation","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"IL2/SHH",2]
["GO:0060575","intestinal epithelial cell differentiation","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"HIF1A/NPY",2]
["GO:0060669","embryonic placenta morphogenesis","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"FGFR2/IL10",2]
["GO:0061050","regulation of cell growth involved in cardiac muscle cell development","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"IGF1/MTOR",2]
["GO:0061217","regulation of mesonephros development","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"VEGFA/GDNF",2]
["GO:0071378","cellular response to growth hormone stimulus","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"PIK3R1/PRL",2]
["GO:0071677","positive regulation of mononuclear cell migration","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"AGER/TNF",2]
["GO:1904376","negative regulation of protein localization to cell periphery","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"TGFB1/BCL2L1",2]
["GO:2001026","regulation of endothelial cell chemotaxis","2/267","25/18866",0.0483495837850761,0.0734884236952466,0.0263225003126955,"FGFR1/VEGFA",2]
["GO:0007188","adenylate cyclase-modulating G protein-coupled receptor signaling pathway","7/267","233/18866",0.0484362447258376,0.0735977388667399,0.0263616554406888,"GNAS/OPRM1/CNR1/GNAL/DRD2/EDNRA/MC1R",7]
["GO:0010656","negative regulation of muscle cell apoptotic process","3/267","58/18866",0.04894665115635,0.074237736702204,0.0265908934944806,"IGF1/PTK2B/DNMT1",3]
["GO:0043489","RNA stabilization","3/267","58/18866",0.04894665115635,0.074237736702204,0.0265908934944806,"FUS/GDNF/MTOR",3]
["GO:0046128","purine ribonucleoside metabolic process","3/267","58/18866",0.04894665115635,0.074237736702204,0.0265908934944806,"DLG1/ADA2/LRRK2",3]
["GO:1902373","negative regulation of mRNA catabolic process","3/267","58/18866",0.04894665115635,0.074237736702204,0.0265908934944806,"FUS/GDNF/MTOR",3]
["GO:1903749","positive regulation of establishment of protein localization to mitochondrion","3/267","58/18866",0.04894665115635,0.074237736702204,0.0265908934944806,"MAPK8/TP53/BCL2",3]
["GO:2000272","negative regulation of signaling receptor activity","3/267","58/18866",0.04894665115635,0.074237736702204,0.0265908934944806,"PPARGC1A/ESR2/PTEN",3]
["GO:1990823","response to leukemia inhibitory factor","4/267","97/18866",0.0489801156920858,0.0742433872649012,0.0265929174450688,"PAX6/SIRT1/XBP1/CREB1",4]
["GO:1990830","cellular response to leukemia inhibitory factor","4/267","97/18866",0.0489801156920858,0.0742433872649012,0.0265929174450688,"PAX6/SIRT1/XBP1/CREB1",4]
["ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"]
["GO:0045121","membrane raft","28/265","329/19559",9.88004604971771e-15,2.14432990535124e-12,1.29142675629952e-12,"TNFRSF1B/TNFRSF1A/PRKACA/PTGS2/DLG1/HDAC6/MAPK1/HTR2A/MAPK3/PRKAR1A/OPRM1/CNR1/PTK2B/KRAS/CDH13/SLC6A3/SHH/NOS3/RET/CTNNB1/FADD/PTCH1/MAPT/LRRK2/DPP4/DLL1/DMD/TNF",28]
["GO:0098857","membrane microdomain","28/265","330/19559",1.06683079868221e-14,2.14432990535124e-12,1.29142675629952e-12,"TNFRSF1B/TNFRSF1A/PRKACA/PTGS2/DLG1/HDAC6/MAPK1/HTR2A/MAPK3/PRKAR1A/OPRM1/CNR1/PTK2B/KRAS/CDH13/SLC6A3/SHH/NOS3/RET/CTNNB1/FADD/PTCH1/MAPT/LRRK2/DPP4/DLL1/DMD/TNF",28]
["GO:0098589","membrane region","28/265","343/19559",2.82266754326846e-14,3.78237450797974e-12,2.27794222790086e-12,"TNFRSF1B/TNFRSF1A/PRKACA/PTGS2/DLG1/HDAC6/MAPK1/HTR2A/MAPK3/PRKAR1A/OPRM1/CNR1/PTK2B/KRAS/CDH13/SLC6A3/SHH/NOS3/RET/CTNNB1/FADD/PTCH1/MAPT/LRRK2/DPP4/DLL1/DMD/TNF",28]
["GO:0150034","distal axon","21/265","309/19559",1.5685092958096e-09,1.57635184228864e-07,9.49360889568966e-08,"NGFR/OXT/CNR1/PTK2B/NTS/GLUL/TOR1A/POLG/GNRH1/NTRK2/DRD2/CDK5/OTX2/CALB2/SNCG/PENK/PTCH1/MAPT/CCK/LRRK2/L1CAM",21]
["GO:0044853","plasma membrane raft","13/265","113/19559",4.44822747008469e-09,3.57637488594809e-07,2.15387856446206e-07,"PRKACA/PTGS2/HDAC6/MAPK1/HTR2A/MAPK3/PRKAR1A/CDH13/SLC6A3/NOS3/CTNNB1/PTCH1/LRRK2",13]
["GO:0005901","caveola","11/265","82/19559",1.3741176492711e-08,9.20658825011639e-07,5.5446852514448e-07,"PTGS2/HDAC6/MAPK1/HTR2A/MAPK3/CDH13/SLC6A3/NOS3/CTNNB1/PTCH1/LRRK2",11]
["GO:0044306","neuron projection terminus","13/265","149/19559",1.25674370013358e-07,7.21729953505286e-06,4.34663234632668e-06,"OXT/NTS/GLUL/POLG/GNRH1/NTRK2/DRD2/CALB2/SNCG/PENK/CCK/LRRK2/DMD",13]
["GO:0043679","axon terminus","12/265","130/19559",2.08590057751474e-07,1.04816504020116e-05,6.31259385300514e-06,"OXT/NTS/GLUL/POLG/GNRH1/NTRK2/DRD2/CALB2/SNCG/PENK/CCK/LRRK2",12]
["GO:0098978","glutamatergic synapse","19/265","361/19559",5.3676428738512e-07,2.3975471503202e-05,1.44392732279038e-05,"DLG1/GSK3B/HTR2A/PRKAR1A/CNR1/PTK2B/APOE/PPP1R1B/RAC1/ADAM10/DRD2/SORCS3/PRKCI/CDK5/VCP/ERBB4/GPC6/LRRK2/MTOR",19]
["GO:0043197","dendritic spine","13/265","175/19559",8.08009168302454e-07,3.24819685657586e-05,1.95623272325857e-05,"NGFR/PRKACA/FUS/COMT/OPRM1/PTK2B/PPP1R1B/RAC1/ADAM10/NTRK2/DRD2/PTEN/MAPT",13]
["GO:0044309","neuron spine","13/265","177/19559",9.19283511524455e-07,3.35956337848028e-05,2.02330342249402e-05,"NGFR/PRKACA/FUS/COMT/OPRM1/PTK2B/PPP1R1B/RAC1/ADAM10/NTRK2/DRD2/PTEN/MAPT",13]
["GO:0005788","endoplasmic reticulum lumen","17/265","308/19559",1.12602577675413e-06,3.77218635212632e-05,2.27180639169692e-05,"COL11A1/PTGS2/APOB/COL1A1/APOE/MEN1/IL6/TOR1A/ADAM10/COL2A1/ALB/SHH/FBN1/F2/PENK/COL11A2/INS",17]
["GO:0043204","perikaryon","12/265","156/19559",1.49005817342246e-06,4.2806437253986e-05,2.57802581000701e-05,"NGFR/FUS/HDAC6/MAPK1/OPRM1/GLUL/GNRH1/DRD2/CDK5/PENK/CCK/LRRK2",12]
["GO:0045211","postsynaptic membrane","16/265","280/19559",1.49077144665623e-06,4.2806437253986e-05,2.57802581000701e-05,"GABRA3/DLG1/COMT/HTR2A/OPRM1/SYNE1/ADAM10/SLC6A3/DRD2/SORCS3/CTNNB1/PTEN/ERBB4/KCTD16/DCC/DMD",16]
["GO:0005719","nuclear euchromatin","6/265","34/19559",5.71724903765966e-06,0.000153222274209279,9.22784055201208e-05,"SIRT1/PPARGC1A/TBP/CREB1/CTNNB1/JUN",6]
["GO:0097060","synaptic membrane","18/265","387/19559",6.1018720515499e-06,0.000153309535295191,9.23309586747682e-05,"GABRA3/DLG1/COMT/HTR2A/OPRM1/CNR1/SYNE1/ADAM10/SLC6A3/DRD2/SORCS3/CTNNB1/PTEN/CALB2/ERBB4/KCTD16/DCC/DMD",18]
["GO:0035097","histone methyltransferase complex","8/265","77/19559",9.58707600957084e-06,0.000226706150343969,0.000136534209424229,"HDAC9/SIRT1/KMT2A/KDM6B/MEN1/KDM6A/KMT2D/HDAC2",8]
["GO:0031983","vesicle lumen","16/265","328/19559",1.12165437071621e-05,0.000250502809459954,0.000150865792552473,"IGF1/GRN/APOB/ADA2/MAPK1/OLFM4/TGFB1/VEGFA/POMC/TTR/ALB/VCP/PENK/SERPINA3/INS/HP",16]
["GO:0090575","RNA polymerase II transcription regulator complex","11/265","161/19559",1.27366333691735e-05,0.000266423709182641,0.000160454184634741,"HIF1A/VDR/TBP/CREB1/ATF4/TP53/CTNNB1/FOS/JUN/TCF4/TLE1",11]
["GO:0005667","transcription regulator complex","18/265","413/19559",1.47440585130328e-05,0.000266423709182641,0.000160454184634741,"CREBBP/HDAC9/HDAC4/REST/EP300/HIF1A/GATA1/VDR/TBP/CREB1/ATF4/TP53/CTNNB1/FOS/JUN/HDAC2/TCF4/TLE1",18]
["GO:0005583","fibrillar collagen trimer","4/265","12/19559",1.49697741726204e-05,0.000266423709182641,0.000160454184634741,"COL11A1/COL1A1/COL2A1/COL11A2",4]
["GO:0098643","banded collagen fibril","4/265","12/19559",1.49697741726204e-05,0.000266423709182641,0.000160454184634741,"COL11A1/COL1A1/COL2A1/COL11A2",4]
["GO:0030669","clathrin-coated endocytic vesicle membrane","6/265","40/19559",1.52431475403004e-05,0.000266423709182641,0.000160454184634741,"APOB/APOE/HLA-DQB1/FZD2/HLA-DRB1/HLA-DQA1",6]
["GO:0030055","cell-substrate junction","18/265","423/19559",2.02836749282161e-05,0.000327472938680938,0.000197221198996114,"FGFR3/MAPK1/MAPK3/OPRM1/PDGFRB/PTK2B/MAP2K2/KRAS/FLNB/RAC1/ADAM10/CDH13/CTNNB1/MAP2K1/FZD2/DPP4/L1CAM/DMD",18]
["GO:0000791","euchromatin","6/265","42/19559",2.03652325050335e-05,0.000327472938680938,0.000197221198996114,"SIRT1/PPARGC1A/TBP/CREB1/CTNNB1/JUN",6]
["GO:0062023","collagen-containing extracellular matrix","18/265","427/19559",2.29759101820053e-05,0.000355242918967929,0.00021394572234256,"COL11A1/FGFR2/DLG1/SFRP1/TGFB1/COL1A1/APOE/COL2A1/CDH13/NCAM1/SHH/FBN1/F2/ADIPOQ/GPC6/SERPINA3/L1CAM/COL11A2",18]
["GO:0034774","secretory granule lumen","15/265","322/19559",3.6006179830873e-05,0.0005193424272315,0.000312774962721249,"IGF1/GRN/ADA2/MAPK1/OLFM4/TGFB1/VEGFA/POMC/TTR/ALB/VCP/PENK/SERPINA3/INS/HP",15]
["GO:0099572","postsynaptic specialization","16/265","361/19559",3.61731043842836e-05,0.0005193424272315,0.000312774962721249,"GABRA3/NGFR/DLG1/MAPK1/TSC2/PTK2B/ADAM10/NTRK2/DRD2/SORCS3/PDLIM5/CDK5/CTNNB1/ERBB4/PTCH1/DCC",16]
["GO:0043209","myelin sheath","6/265","47/19559",3.93898241452613e-05,0.000546024458841209,0.000328844266911438,"DLG1/GLUL/SRD5A1/PRKCI/BCL2/PTEN",6]
["GO:0060205","cytoplasmic vesicle lumen","15/265","326/19559",4.1468341007225e-05,0.000555675769496815,0.000334656787075851,"IGF1/GRN/ADA2/MAPK1/OLFM4/TGFB1/VEGFA/POMC/TTR/ALB/VCP/PENK/SERPINA3/INS/HP",15]
["GO:0031968","organelle outer membrane","12/265","218/19559",4.46883453255879e-05,0.000571669431234532,0.000344289000219802,"ACSL4/PTGS2/BAX/TSPO/MFN2/CNR1/SYNE1/BCL2L1/BCL2/LRRK2/MAOA/MTOR",12]
["GO:0098984","neuron to neuron synapse","16/265","368/19559",4.55060243768782e-05,0.000571669431234532,0.000344289000219802,"NGFR/DLG1/MAPK1/TSC2/PTK2B/ADAM10/NTRK2/DRD2/SORCS3/PDLIM5/CDK5/CTNNB1/ERBB4/PENK/PTCH1/DCC",16]
["GO:0019867","outer membrane","12/265","220/19559",4.88283294263615e-05,0.000594817831193859,0.000358230168040292,"ACSL4/PTGS2/BAX/TSPO/MFN2/CNR1/SYNE1/BCL2L1/BCL2/LRRK2/MAOA/MTOR",12]
["GO:0098562","cytoplasmic side of membrane","11/265","188/19559",5.35279883564852e-05,0.000632889744685502,0.000381159050216458,"DLG1/GNAS/GNB3/PTK2B/MAP2K2/KRAS/GNAL/GNRH1/PTEN/ATP2A2/LRRK2",11]
["GO:0005925","focal adhesion","17/265","415/19559",5.54178087115971e-05,0.000636513117201772,0.000383341233193003,"FGFR3/MAPK1/MAPK3/OPRM1/PDGFRB/PTK2B/MAP2K2/KRAS/FLNB/RAC1/ADAM10/CDH13/CTNNB1/MAP2K1/FZD2/DPP4/L1CAM",17]
["GO:0014069","postsynaptic density","15/265","337/19559",6.04232171287481e-05,0.000674725924604353,0.000406354968994505,"NGFR/DLG1/MAPK1/TSC2/PTK2B/ADAM10/NTRK2/DRD2/SORCS3/PDLIM5/CDK5/CTNNB1/ERBB4/PTCH1/DCC",15]
["GO:0032279","asymmetric synapse","15/265","343/19559",7.36719418932521e-05,0.000800435693002361,0.000482063915659971,"NGFR/DLG1/MAPK1/TSC2/PTK2B/ADAM10/NTRK2/DRD2/SORCS3/PDLIM5/CDK5/CTNNB1/ERBB4/PTCH1/DCC",15]
["GO:0016234","inclusion body","7/265","78/19559",9.01096244328022e-05,0.000945206793254035,0.000569252585620393,"HDAC6/ATF4/SQSTM1/PRKN/MAPT/LRRK2/GPX1",7]
["GO:0034708","methyltransferase complex","8/265","105/19559",9.16991665097198e-05,0.000945206793254035,0.000569252585620393,"HDAC9/SIRT1/KMT2A/KDM6B/MEN1/KDM6A/KMT2D/HDAC2",8]
["GO:0043195","terminal bouton","6/265","56/19559",0.000107578736598186,0.00108116630281177,0.000651134458357443,"OXT/POLG/NTRK2/CALB2/CCK/LRRK2",6]
["GO:0005775","vacuolar lumen","10/265","173/19559",0.000129092667679905,0.00126573786359321,0.000762293031229218,"GRN/APOB/ADA2/MAPK1/PDGFRB/TTR/IDUA/VCP/GPC6/SERPINA3",10]
["GO:0045334","clathrin-coated endocytic vesicle","6/265","59/19559",0.00014431592486873,0.0013813095666007,0.000831896308767116,"APOB/APOE/HLA-DQB1/FZD2/HLA-DRB1/HLA-DQA1",6]
["GO:0098644","complex of collagen trimers","4/265","21/19559",0.000164408526436306,0.0015370285494743,0.000925678361820084,"COL11A1/COL1A1/COL2A1/COL11A2",4]
["GO:0099055","integral component of postsynaptic membrane","8/265","117/19559",0.00019510985103763,0.00178259454811653,0.00107357095068552,"GABRA3/HTR2A/OPRM1/SLC6A3/DRD2/SORCS3/ERBB4/DCC",8]
["GO:0030426","growth cone","10/265","184/19559",0.000213460161888327,0.00190691077953572,0.00114844063706,"NGFR/CNR1/PTK2B/TOR1A/CDK5/OTX2/PTCH1/MAPT/LRRK2/L1CAM",10]
["GO:0099699","integral component of synaptic membrane","9/265","154/19559",0.000257544305175878,0.00222365232729693,0.00133919883550221,"GABRA3/HTR2A/OPRM1/CNR1/SLC6A3/DRD2/SORCS3/ERBB4/DCC",9]
["GO:0098936","intrinsic component of postsynaptic membrane","8/265","122/19559",0.000259979252196407,0.00222365232729693,0.00133919883550221,"GABRA3/HTR2A/OPRM1/SLC6A3/DRD2/SORCS3/ERBB4/DCC",8]
["GO:0030427","site of polarized growth","10/265","191/19559",0.000288204888724625,0.00241371594306873,0.00145366500891806,"NGFR/CNR1/PTK2B/TOR1A/CDK5/OTX2/PTCH1/MAPT/LRRK2/L1CAM",10]
["GO:0005741","mitochondrial outer membrane","10/265","192/19559",0.000300482245411925,0.00246518087052232,0.00148465985917814,"ACSL4/BAX/TSPO/MFN2/CNR1/BCL2L1/BCL2/LRRK2/MAOA/MTOR",10]
["GO:0030139","endocytic vesicle","13/265","313/19559",0.000364391746561316,0.00292970964235298,0.00176442319387585,"APOB/APOE/FLNB/DRD2/NOS3/HLA-DQB1/FZD2/PTCH1/HLA-DRB1/HLA-DQA1/DPP4/MTOR/HP",13]
["GO:1990907","beta-catenin-TCF complex","3/265","11/19559",0.000374375937228578,0.00295096326991938,0.00177722323142565,"CTNNB1/TCF4/TLE1",3]
["GO:0009898","cytoplasmic side of plasma membrane","9/265","164/19559",0.000409658119866678,0.00316697238820008,0.00190731513298251,"DLG1/GNAS/GNB3/PTK2B/MAP2K2/KRAS/GNAL/PTEN/ATP2A2",9]
["GO:0099240","intrinsic component of synaptic membrane","9/265","166/19559",0.000447553351483153,0.00339464994898542,0.00204443437618918,"GABRA3/HTR2A/OPRM1/CNR1/SLC6A3/DRD2/SORCS3/ERBB4/DCC",9]
["GO:0016605","PML body","7/265","102/19559",0.000478399576547857,0.00355796168652587,0.00214278918015436,"ATRX/SIRT1/PPARGC1A/TP53/SQSTM1/PTEN/MTOR",7]
["GO:1990909","Wnt signalosome","3/265","12/19559",0.000494177991580562,0.00355796168652587,0.00214278918015436,"GSK3B/CTNNB1/LRRK2",3]
["GO:0099056","integral component of presynaptic membrane","6/265","74/19559",0.000501040353793825,0.00355796168652587,0.00214278918015436,"HTR2A/OPRM1/CNR1/SLC6A3/DRD2/ERBB4",6]
["GO:0030133","transport vesicle","15/265","410/19559",0.000504487104805906,0.00355796168652587,0.00214278918015436,"IGF1/FGFR3/NTS/NGF/TOR1A/ADAM10/DRD2/BCL2L1/BDNF/HLA-DQB1/PENK/LRRK2/HLA-DRB1/HLA-DQA1/INS",15]
["GO:0031594","neuromuscular junction","6/265","76/19559",0.000578134408002184,0.00400706951753238,0.00241326522396556,"HDAC4/PRKACA/DLG1/P2RX7/PRKAR1A/CDK5",6]
["GO:0042627","chylomicron","3/265","13/19559",0.000636013523468509,0.00426129060723901,0.00256637035785539,"APOB/APOE/LPL",3]
["GO:0044666","MLL3/4 complex","3/265","13/19559",0.000636013523468509,0.00426129060723901,0.00256637035785539,"KDM6B/KDM6A/KMT2D",3]
["GO:0031252","cell leading edge","15/265","421/19559",0.000662320478916265,0.00436480053318588,0.00262870940726041,"GABRA3/HDAC6/OPRM1/PDGFRB/PTK2B/PIK3CA/ATF4/RAC1/S100B/PRKCI/CDK5/INPPL1/CTNNB1/MAPT/DPP4",15]
["GO:0000800","lateral element","3/265","14/19559",0.000801390457879885,0.0051961123236728,0.00312936851124573,"BRCA1/SMC3/BRCA2",3]
["GO:0098889","intrinsic component of presynaptic membrane","6/265","83/19559",0.000922643299972994,0.00588734296173244,0.00354566347525127,"HTR2A/OPRM1/CNR1/SLC6A3/DRD2/ERBB4",6]
["GO:0032839","dendrite cytoplasm","4/265","34/19559",0.00110951798110659,0.00696915981882578,0.00419718973115981,"MAPK1/OPRM1/SOD1/LRRK2",4]
["GO:0120111","neuron projection cytoplasm","6/265","87/19559",0.00118020511859295,0.00729911473345179,0.00439590570488063,"MAPK1/HIF1A/OPRM1/SOD1/MAPT/LRRK2",6]
["GO:0042613","MHC class II protein complex","3/265","16/19559",0.00120843801319729,0.00736048608038351,0.00443286671507779,"HLA-DQB1/HLA-DRB1/HLA-DQA1",3]
["GO:0031904","endosome lumen","4/265","35/19559",0.00123947606417721,0.00743685638506329,0.00447886087605278,"APOB/NGF/PRL/INS",4]
["GO:0042734","presynaptic membrane","8/265","156/19559",0.00132095277001743,0.0078091619639266,0.00470308261770913,"HTR2A/OPRM1/CNR1/SLC6A3/DRD2/CTNNB1/ERBB4/KCTD16",8]
["GO:0034358","plasma lipoprotein particle","4/265","36/19559",0.00137971754484944,0.00792352075756393,0.00477195541827626,"PON1/APOB/APOE/LPL",4]
["GO:1990777","lipoprotein particle","4/265","36/19559",0.00137971754484944,0.00792352075756393,0.00477195541827626,"PON1/APOB/APOE/LPL",4]
["GO:0035578","azurophil granule lumen","6/265","91/19559",0.00148952500339711,0.00840016390597725,0.00505901465926883,"GRN/ADA2/MAPK1/TTR/VCP/SERPINA3",6]
["GO:0005770","late endosome","11/265","278/19559",0.00150450696823473,0.00840016390597725,0.00505901465926883,"GRN/HDAC6/MAPK1/MAPK3/PRKAR1A/MAP2K2/SQSTM1/MAP2K1/LRRK2/HLA-DRB1/SLC29A3",11]
["GO:0030666","endocytic vesicle membrane","8/265","164/19559",0.00181354635571534,0.00998692650681598,0.0060146454479384,"APOB/APOE/NOS3/HLA-DQB1/FZD2/PTCH1/HLA-DRB1/HLA-DQA1",8]
["GO:0032994","protein-lipid complex","4/265","39/19559",0.00186633781370874,0.0100357203085264,0.00604403160764879,"PON1/APOB/APOE/LPL",4]
["GO:0016328","lateral plasma membrane","5/265","65/19559",0.00187233587845642,0.0100357203085264,0.00604403160764879,"ERBB3/DLG1/DRD2/CTNNB1/DMD",5]
["GO:0031093","platelet alpha granule lumen","5/265","67/19559",0.00214180513938041,0.0113290219214595,0.00682292495924508,"IGF1/TGFB1/VEGFA/ALB/SERPINA3",5]
["GO:0031234","extrinsic component of cytoplasmic side of plasma membrane","6/265","99/19559",0.00228947615769313,0.0118767919494631,0.00715282049849834,"GNAS/GNB3/PTK2B/KRAS/GNAL/ATP2A2",6]
["GO:0034361","very-low-density lipoprotein particle","3/265","20/19559",0.00236354068646032,0.0118767919494631,0.00715282049849834,"APOB/APOE/LPL",3]
["GO:0034385","triglyceride-rich plasma lipoprotein particle","3/265","20/19559",0.00236354068646032,0.0118767919494631,0.00715282049849834,"APOB/APOE/LPL",3]
["GO:0071682","endocytic vesicle lumen","3/265","20/19559",0.00236354068646032,0.0118767919494631,0.00715282049849834,"APOB/APOE/HP",3]
["GO:0032838","plasma membrane bounded cell projection cytoplasm","9/265","211/19559",0.00240746518432091,0.0119481605444075,0.00719580237028991,"PRKACA/GLI2/MAPK1/HIF1A/PRKAR1A/OPRM1/SOD1/MAPT/LRRK2",9]
["GO:0019897","extrinsic component of plasma membrane","8/265","172/19559",0.00244103771615682,0.0119670385596956,0.00720717169083528,"GNAS/GNB3/PTK2B/KRAS/CDH13/GNAL/CTNNB1/ATP2A2",8]
["GO:0099568","cytoplasmic region","10/265","254/19559",0.00252808413506477,0.0122444556903137,0.00737424668439947,"PRKACA/GLI2/MAPK1/HIF1A/PRKAR1A/OPRM1/SOD1/CTNNB1/MAPT/LRRK2",10]
["GO:0005911","cell-cell junction","15/265","493/19559",0.00310318781258143,0.0148509702459254,0.00894402502373095,"NGFR/DLG1/P2RX7/VEGFA/MAP2K2/ADAM10/AKT1/PIK3R1/PDLIM5/PRKCI/CTNNB1/CALB2/ATP2A2/DPP4/DLL1",15]
["GO:0019898","extrinsic component of membrane","11/265","306/19559",0.00316791517701092,0.0149823753077458,0.00902316397167197,"GNAS/GNB3/PTK2B/PIK3CA/KRAS/TOR1A/CDH13/GNAL/PIK3R1/CTNNB1/ATP2A2",11]
["GO:0098982","GABA-ergic synapse","5/265","74/19559",0.00330953992831844,0.0154701750137676,0.0093169422706639,"GABRA3/CNR1/CDH13/DRD2/ERBB4",5]
["GO:0070382","exocytic vesicle","9/265","223/19559",0.00347857127447622,0.0160733983027522,0.00968023464161561,"IGF1/NGF/TOR1A/ADAM10/DRD2/BCL2L1/BDNF/PENK/LRRK2",9]
["GO:0046930","pore complex","3/265","23/19559",0.00356347596834386,0.0162786061281163,0.00980382144400823,"BAX/ADAM10/BCL2",3]
["GO:0017053","transcription repressor complex","5/265","76/19559",0.00371376147457175,0.0167745181210994,0.010102485383223,"HDAC4/REST/GATA1/JUN/HDAC2",5]
["GO:0000118","histone deacetylase complex","5/265","77/19559",0.00392860746245815,0.0175477799989797,0.0105681838171389,"HDAC9/HDAC4/HDAC6/RERE/HDAC2",5]
["GO:0072562","blood microparticle","7/265","148/19559",0.00410030436087475,0.0181134324513368,0.0109088490804071,"PON1/TGFB1/APOE/ALB/F2/SERPINA3/HP",7]
["GO:0000792","heterochromatin","5/265","78/19559",0.00415220146323915,0.0181433150893711,0.0109268459558925,"ATRX/SIRT1/DNMT1/CDKN2A/MECP2",5]
["GO:0042611","MHC protein complex","3/265","25/19559",0.00453658618972903,0.0194011451943731,0.011684376524498,"HLA-DQB1/HLA-DRB1/HLA-DQA1",3]
["GO:0099522","region of cytosol","3/265","25/19559",0.00453658618972903,0.0194011451943731,0.011684376524498,"PTEN/LRRK2/MTOR",3]
["GO:0043292","contractile fiber","9/265","238/19559",0.0053083217612389,0.0224625826107162,0.0135281330203318,"HDAC4/SYNE1/IDO1/FLNB/SQSTM1/PDLIM5/CTNNB1/NEB/DMD",9]
["GO:0030665","clathrin-coated vesicle membrane","6/265","118/19559",0.00544680019239634,0.0228084758056597,0.0137364478536311,"APOB/APOE/HLA-DQB1/FZD2/HLA-DRB1/HLA-DQA1",6]
["GO:0031045","dense core granule","3/265","27/19559",0.00565568330935246,0.0231998437791805,0.0139721499586581,"NPY/SOD1/PENK",3]
["GO:0034364","high-density lipoprotein particle","3/265","27/19559",0.00565568330935246,0.0231998437791805,0.0139721499586581,"PON1/APOB/APOE",3]
["GO:0045177","apical part of cell","13/265","433/19559",0.00638904373377398,0.0259433897068398,0.0156244557019459,"ERBB3/DLG1/ABCB1/GNAS/PDGFRB/IL6R/PRKCI/CTNNB1/PTEN/PTCH1/DPP4/DLL1/AGER",13]
["GO:0005581","collagen trimer","5/265","87/19559",0.00658972326504457,0.0264906875254792,0.0159540668522132,"COL11A1/COL1A1/COL2A1/ADIPOQ/COL11A2",5]
["GO:0071556","integral component of lumenal side of endoplasmic reticulum membrane","3/265","29/19559",0.00692623976858943,0.0272959235325107,0.0164390217661101,"HLA-DQB1/HLA-DRB1/HLA-DQA1",3]
["GO:0098553","lumenal side of endoplasmic reticulum membrane","3/265","29/19559",0.00692623976858943,0.0272959235325107,0.0164390217661101,"HLA-DQB1/HLA-DRB1/HLA-DQA1",3]
["GO:0008021","synaptic vesicle","8/265","205/19559",0.00699373165136468,0.0272959235325107,0.0164390217661101,"NGF/TOR1A/ADAM10/DRD2/BCL2L1/BDNF/PENK/LRRK2",8]
["GO:0030017","sarcomere","8/265","207/19559",0.00739772139174958,0.0285950384565705,0.0172214161953684,"HDAC4/SYNE1/FLNB/SQSTM1/PDLIM5/CTNNB1/NEB/DMD",8]
["GO:0031253","cell projection membrane","11/265","344/19559",0.0075026088813222,0.0287242740027764,0.0172992485484121,"GABRA3/DLG1/OPRM1/ATF4/RAC1/DRD2/CTNNB1/PTCH1/MAPT/DPP4/DMD",11]
["GO:0005952","cAMP-dependent protein kinase complex","2/265","10/19559",0.00765989789583679,0.0287783079824896,0.0173317906152726,"PRKACA/PRKAR1A",2]
["GO:0044754","autolysosome","2/265","10/19559",0.00765989789583679,0.0287783079824896,0.0173317906152726,"SQSTM1/LRRK2",2]
["GO:0031091","platelet alpha granule","5/265","91/19559",0.00794141069289141,0.0295596953568736,0.0178023826448833,"IGF1/TGFB1/VEGFA/ALB/SERPINA3",5]
["GO:0030018","Z disc","6/265","128/19559",0.00802232410617395,0.0295869200979993,0.0178187787969098,"HDAC4/FLNB/PDLIM5/CTNNB1/NEB/DMD",6]
["GO:0016607","nuclear speck","12/265","401/19559",0.00884155922958045,0.0321262675994516,0.0193481056503636,"HDAC4/PRKACA/GLI2/HIF1A/NR3C1/ATF4/FTO/INPPL1/AR/BDNF/PRKN/MAPT",12]
["GO:0005637","nuclear inner membrane","4/265","60/19559",0.00887068582969932,0.0321262675994516,0.0193481056503636,"PTGS2/P2RX7/SIRT1/LBR",4]
["GO:0043220","Schmidt-Lanterman incisure","2/265","11/19559",0.0092789027755275,0.0333046331764469,0.0200577785561215,"PRKCI/PTEN",2]
["GO:0032589","neuron projection membrane","4/265","61/19559",0.00939431875380695,0.0334204968055787,0.0201275576467219,"GABRA3/OPRM1/ATF4/MAPT",4]
["GO:0016324","apical plasma membrane","11/265","361/19559",0.0105352506199438,0.0371506206071704,0.0223740317875077,"ERBB3/DLG1/ABCB1/GNAS/PDGFRB/IL6R/PRKCI/PTEN/DPP4/DLL1/AGER",11]
["GO:0005834","heterotrimeric G-protein complex","3/265","34/19559",0.0107943713091748,0.0372807629276587,0.0224524102470843,"GNAS/GNB3/GNAL",3]
["GO:1905360","GTPase complex","3/265","34/19559",0.0107943713091748,0.0372807629276587,0.0224524102470843,"GNAS/GNB3/GNAL",3]
["GO:0030877","beta-catenin destruction complex","2/265","12/19559",0.0110358477323169,0.0372807629276587,0.0224524102470843,"GSK3B/CTNNB1",2]
["GO:0044327","dendritic spine head","2/265","12/19559",0.0110358477323169,0.0372807629276587,0.0224524102470843,"FUS/PPP1R1B",2]
["GO:0098992","neuronal dense core vesicle","2/265","12/19559",0.0110358477323169,0.0372807629276587,0.0224524102470843,"NPY/PENK",2]
["GO:0031674","I band","6/265","140/19559",0.0121497482373749,0.040701656595206,0.0245126499525986,"HDAC4/FLNB/PDLIM5/CTNNB1/NEB/DMD",6]
["GO:0030016","myofibril","8/265","227/19559",0.0124664558949082,0.041242413691356,0.0248383219403296,"HDAC4/SYNE1/FLNB/SQSTM1/PDLIM5/CTNNB1/NEB/DMD",8]
["GO:0097546","ciliary base","3/265","36/19559",0.0126274541196246,0.041242413691356,0.0248383219403296,"PRKACA/GLI2/PRKAR1A",3]
["GO:0098576","lumenal side of membrane","3/265","36/19559",0.0126274541196246,0.041242413691356,0.0248383219403296,"HLA-DQB1/HLA-DRB1/HLA-DQA1",3]
["GO:0005635","nuclear envelope","13/265","473/19559",0.0127617975997826,0.041242413691356,0.0248383219403296,"VRK2/PTGS2/BAX/P2RX7/SIRT1/MAPK3/SYNE1/TOR1A/TP53/LBR/BCL2L1/BCL2/MTOR",13]
["GO:0034362","low-density lipoprotein particle","2/265","13/19559",0.0129267266793802,0.041242413691356,0.0248383219403296,"APOB/APOE",2]
["GO:0098691","dopaminergic synapse","2/265","13/19559",0.0129267266793802,0.041242413691356,0.0248383219403296,"SLC6A3/DRD2",2]
["GO:0005796","Golgi lumen","5/265","103/19559",0.0131288241694465,0.04155738044187,0.0250280112637604,"TGFB1/NGF/F2/GPC6/INS",5]
["GO:0044304","main axon","4/265","68/19559",0.0136263460094379,0.0427952429358908,0.0257735163007459,"TNFRSF1B/DLG1/MAPT/CCK",4]
["GO:0043218","compact myelin","2/265","14/19559",0.0149476160496303,0.0465809430383827,0.0280534613742551,"PRKCI/PTEN",2]
["GO:0016235","aggresome","3/265","39/19559",0.0156912227399328,0.048353441225287,0.0291209517722336,"HDAC6/SQSTM1/PRKN",3]
["GO:0045171","intercellular bridge","4/265","71/19559",0.0157569671654542,0.048353441225287,0.0291209517722336,"PRKACA/OLFM4/GSTM1/PRKCI",4]
["GO:0030136","clathrin-coated vesicle","7/265","194/19559",0.016803166049265,0.0509041382975983,0.0306571139262833,"APOB/APOE/ADAM10/HLA-DQB1/FZD2/HLA-DRB1/HLA-DQA1",7]
["GO:0005639","integral component of nuclear inner membrane","2/265","15/19559",0.017094673308895,0.0509041382975983,0.0306571139262833,"P2RX7/LBR",2]
["GO:0031229","intrinsic component of nuclear inner membrane","2/265","15/19559",0.017094673308895,0.0509041382975983,0.0306571139262833,"P2RX7/LBR",2]
["GO:0071565","nBAF complex","2/265","15/19559",0.017094673308895,0.0509041382975983,0.0306571139262833,"ARID1B/SMARCB1",2]
["GO:0099060","integral component of postsynaptic specialization membrane","4/265","74/19559",0.0180860599940644,0.0534602655706902,0.0321965464290619,"GABRA3/SORCS3/ERBB4/DCC",4]
["GO:0005802","trans-Golgi network","8/265","245/19559",0.0188811750426935,0.0540582115874016,0.0325566605527687,"GRN/RBFOX1/RAC1/ADAM10/HLA-DQB1/LRRK2/HLA-DRB1/HLA-DQA1",8]
["GO:0031514","motile cilium","7/265","199/19559",0.0190382040554467,0.0540582115874016,0.0325566605527687,"PRKACA/GLI2/HIF1A/PRKAR1A/PMFBP1/DRD2/SQSTM1",7]
["GO:0000795","synaptonemal complex","3/265","42/19559",0.0191367440532784,0.0540582115874016,0.0325566605527687,"BRCA1/SMC3/BRCA2",3]
["GO:0099086","synaptonemal structure","3/265","42/19559",0.0191367440532784,0.0540582115874016,0.0325566605527687,"BRCA1/SMC3/BRCA2",3]
["GO:0005766","primary lysosome","6/265","155/19559",0.019166069816499,0.0540582115874016,0.0325566605527687,"GRN/ADA2/MAPK1/TTR/VCP/SERPINA3",6]
["GO:0042582","azurophil granule","6/265","155/19559",0.019166069816499,0.0540582115874016,0.0325566605527687,"GRN/ADA2/MAPK1/TTR/VCP/SERPINA3",6]
["GO:0005767","secondary lysosome","2/265","16/19559",0.0193641354939946,0.0540582115874016,0.0325566605527687,"SQSTM1/LRRK2",2]
["GO:0035098","ESC/E(Z) complex","2/265","16/19559",0.0193641354939946,0.0540582115874016,0.0325566605527687,"SIRT1/HDAC2",2]
["GO:0030027","lamellipodium","7/265","201/19559",0.019987957363522,0.0554148886905921,0.0333737219136847,"PTK2B/PIK3CA/RAC1/CDK5/INPPL1/CTNNB1/DPP4",7]
["GO:0036126","sperm flagellum","5/265","115/19559",0.0202262902161123,0.0556915662114873,0.0335403514758892,"PRKACA/PRKAR1A/PMFBP1/DRD2/SQSTM1",5]
["GO:0032590","dendrite membrane","3/265","43/19559",0.020370671598,0.055707550900653,0.0335499782852846,"GABRA3/OPRM1/ATF4",3]
["GO:0098948","intrinsic component of postsynaptic specialization membrane","4/265","77/19559",0.0206184860954679,0.0560042662863384,0.0337286756895989,"GABRA3/SORCS3/ERBB4/DCC",4]
["GO:1904949","ATPase complex","4/265","78/19559",0.0215085555350478,0.0580297941281155,0.0349485536775768,"ARID1B/SMARCB1/VCP/HDAC2",4]
["GO:0031965","nuclear membrane","9/265","301/19559",0.0219817054523182,0.0589109706122128,0.0354792438879522,"PTGS2/P2RX7/SIRT1/SYNE1/TOR1A/TP53/LBR/BCL2L1/BCL2",9]
["GO:0099634","postsynaptic specialization membrane","5/265","118/19559",0.0223269054684086,0.0594398410483461,0.0357977571121225,"GABRA3/DLG1/SORCS3/ERBB4/DCC",5]
["GO:0097729","9+2 motile cilium","5/265","120/19559",0.0238031115734322,0.0629081034935387,0.0378865247538987,"PRKACA/PRKAR1A/PMFBP1/DRD2/SQSTM1",5]
["GO:0031143","pseudopodium","2/265","18/19559",0.0242556120435286,0.0629081034935387,0.0378865247538987,"MAPK1/MAPK3",2]
["GO:0097440","apical dendrite","2/265","18/19559",0.0242556120435286,0.0629081034935387,0.0378865247538987,"PPARGC1A/PTK2B",2]
["GO:0099524","postsynaptic cytosol","2/265","18/19559",0.0242556120435286,0.0629081034935387,0.0378865247538987,"PTEN/MTOR",2]
["GO:0005912","adherens junction","6/265","166/19559",0.0257953260036961,0.0664725708556784,0.0400332319895418,"DLG1/VEGFA/ADAM10/PDLIM5/CTNNB1/DLL1",6]
["GO:0016514","SWI/SNF complex","2/265","19/19559",0.0268704855199447,0.0688021348982023,0.0414362163566026,"ARID1B/SMARCB1",2]
["GO:0098685","Schaffer collateral - CA1 synapse","4/265","84/19559",0.027340450006919,0.069230259045997,0.041694054937364,"PRKCI/CDK5/CTNNB1/DCC",4]
["GO:0009897","external side of plasma membrane","11/265","417/19559",0.0273821173838645,0.069230259045997,0.041694054937364,"ABCB1/P2RX7/FGF8/IL17A/CDH13/NCAM1/ACE/IL6R/F2/HLA-DRB1/TNF",11]
["GO:0005721","pericentric heterochromatin","2/265","20/19559",0.0295934793903319,0.0743536169682088,0.0447796069722127,"ATRX/DNMT1",2]
["GO:0098858","actin-based cell projection","7/265","220/19559",0.0307056146188917,0.0766686774956179,0.046173856569762,"TGFB1/CDK5/INPPL1/CTNNB1/CALB2/LRRK2/DMD",7]
["GO:0099061","integral component of postsynaptic density membrane","3/265","51/19559",0.031782090407507,0.0788666687889989,0.0474976009988734,"SORCS3/ERBB4/DCC",3]
["GO:0031256","leading edge membrane","6/265","175/19559",0.0322376062275745,0.0795062435796623,0.047882786130721,"GABRA3/OPRM1/ATF4/RAC1/MAPT/DPP4",6]
["GO:0034399","nuclear periphery","5/265","131/19559",0.0330421095355537,0.0809934636176377,0.0487784672219342,"SMC3/ATF4/MEN1/TP53/MAPT",5]
["GO:0097038","perinuclear endoplasmic reticulum","2/265","22/19559",0.0353503548412202,0.0861263190677001,0.0518697391609611,"ADAM10/PIK3R1",2]
["GO:0098839","postsynaptic density membrane","4/265","92/19559",0.0364536277380015,0.0882792671727505,0.0531663562443902,"DLG1/SORCS3/ERBB4/DCC",4]
["GO:0099146","intrinsic component of postsynaptic density membrane","3/265","54/19559",0.0367620145402247,0.0884929930848523,0.0532950730806914,"SORCS3/ERBB4/DCC",3]
["GO:0005798","Golgi-associated vesicle","6/265","181/19559",0.0370670060791293,0.0886960502607738,0.0534173646503744,"ADAM10/GNRH1/HLA-DQB1/LRRK2/HLA-DRB1/HLA-DQA1",6]
["GO:0030662","coated vesicle membrane","6/265","183/19559",0.0387742698537519,0.0922322868710549,0.0555470698621174,"APOB/APOE/HLA-DQB1/FZD2/HLA-DRB1/HLA-DQA1",6]
["GO:0043202","lysosomal lumen","4/265","96/19559",0.0415917118581557,0.0983521656881093,0.059232778497683,"APOB/PDGFRB/IDUA/GPC6",4]
["GO:1904115","axon cytoplasm","3/265","57/19559",0.0421173021383278,0.0990126050269462,0.0596305293432773,"HIF1A/SOD1/MAPT",3]
["GO:0035861","site of double-strand break","3/265","61/19559",0.0498300071076195,0.116463156146878,0.0701401568834301,"TIMELESS/TP53/VCP",3]
["ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"]
["GO:0030546","signaling receptor activator activity","43/264","492/18352",1.13076408190814e-21,7.51958114468916e-19,5.23722311620614e-19,"IGF1/GRN/TG/ADA2/OXT/TGFB1/FGF8/CCL2/IL2/IFNG/IL17A/VEGFA/IL1A/POMC/TTR/NPY/IL1B/LIF/NTS/NGF/IL6/IL10/GNRH1/IL18/SST/FGF17/SHH/CDK5/FBN1/GDNF/CXCL8/PRKCE/PRL/LEP/BDNF/F2/ADIPOQ/PENK/CCK/DPP4/IFNA1/TNF/INS",43]
["GO:0048018","receptor ligand activity","41/264","487/18352",4.38166657525135e-20,1.45690413627107e-17,1.0147017332161e-17,"IGF1/GRN/TG/ADA2/OXT/TGFB1/FGF8/CCL2/IL2/IFNG/IL17A/VEGFA/IL1A/POMC/TTR/NPY/IL1B/LIF/NTS/NGF/IL6/IL10/GNRH1/IL18/SST/FGF17/SHH/FBN1/GDNF/CXCL8/PRL/LEP/BDNF/F2/ADIPOQ/PENK/CCK/DPP4/IFNA1/TNF/INS",41]
["GO:0140297","DNA-binding transcription factor binding","27/264","347/18352",1.05075591170458e-12,2.32917560427849e-10,1.62221965315795e-10,"CREBBP/HDAC9/POU1F1/HDAC4/GSK3B/FUS/ESR1/SIRT1/SMARCB1/EP300/HIF1A/PPARGC1A/VDR/TBP/SRF/CREB1/ATF4/CDKN2A/CTNNB1/FOS/BCL2/JUN/MED12/HDAC2/TCF4/TLE1/DLL1",27]
["GO:0005179","hormone activity","16/264","122/18352",2.25371433733995e-11,3.74680008582766e-09,2.60956396955152e-09,"IGF1/TG/OXT/POMC/TTR/NPY/NTS/GNRH1/SST/FBN1/PRL/LEP/ADIPOQ/PENK/CCK/INS",16]
["GO:0002020","protease binding","16/264","137/18352",1.3368243367098e-10,1.77797636782404e-08,1.23832149084698e-08,"GSK3B/COL1A1/BRCA2/POLG/TP53/SLC6A3/NTRK2/DVL3/VCP/FADD/BCL2/PTEN/PRKN/DPP4/TNF/INS",16]
["GO:0061629","RNA polymerase II-specific DNA-binding transcription factor binding","21/264","267/18352",3.161624344139e-10,3.09666341798115e-08,2.15675805921916e-08,"CREBBP/POU1F1/GSK3B/FUS/ESR1/SIRT1/SMARCB1/EP300/HIF1A/PPARGC1A/VDR/TBP/SRF/CREB1/CDKN2A/CTNNB1/FOS/JUN/MED12/HDAC2/DLL1",21]
["GO:0031625","ubiquitin protein ligase binding","22/264","297/18352",3.71064676501243e-10,3.09666341798115e-08,2.15675805921916e-08,"PAX6/BRCA1/TNFRSF1B/NGFR/ERBB3/PRKACA/GSK3B/ABCB1/HDAC6/HIF1A/BAG1/PRKAR1A/PPARGC1A/MFN2/PTK2B/TP53/SQSTM1/VCP/BCL2/JUN/PRKN/MC1R",22]
["GO:0001085","RNA polymerase II transcription factor binding","11/264","56/18352",3.72530937501491e-10,3.09666341798115e-08,2.15675805921916e-08,"CREBBP/POU1F1/HDAC4/GSK3B/EP300/GATA1/ATF4/TP53/RERE/CTNNB1/AR",11]
["GO:0044389","ubiquitin-like protein ligase binding","22/264","316/18352",1.19580058560478e-09,8.83563766030199e-08,6.15382757504215e-08,"PAX6/BRCA1/TNFRSF1B/NGFR/ERBB3/PRKACA/GSK3B/ABCB1/HDAC6/HIF1A/BAG1/PRKAR1A/PPARGC1A/MFN2/PTK2B/TP53/SQSTM1/VCP/BCL2/JUN/PRKN/MC1R",22]
["GO:0005126","cytokine receptor binding","20/264","271/18352",2.56726164579786e-09,1.70722899445558e-07,1.18904749910638e-07,"TGFB1/CCL2/IL2/IFNG/VEGFA/IL1A/IL1B/LIF/NGF/IL6/IL10/PIK3R1/IL18/IL6R/FADD/CXCL8/PRL/BDNF/IFNA1/TNF",20]
["GO:0001664","G protein-coupled receptor binding","20/264","293/18352",9.74900303254121e-09,5.89371546967264e-07,4.10484338212261e-07,"TAC1/GNAS/ADA2/OXT/SFRP1/CCL2/IL2/POMC/NPY/PPP1R1B/NTS/GNAL/ACE/DVL3/CXCL8/ATP2A2/PTPN11/PENK/PRKN/PTCH1",20]
["GO:0008083","growth factor activity","15/264","162/18352",1.29870097047937e-08,7.19696787807319e-07,5.01253006149934e-07,"IGF1/GRN/ADA2/TGFB1/FGF8/IL2/VEGFA/LIF/NGF/IL6/IL10/FGF17/GDNF/BDNF/F2",15]
["GO:0004714","transmembrane receptor protein tyrosine kinase activity","10/264","61/18352",1.51443999136247e-08,7.74694303273878e-07,5.39557567772863e-07,"ERBB3/FGFR2/FGFR3/FGFR1/PDGFRB/NTRK2/RET/ALK/ERBB4/CSF1R",10]
["GO:0002039","p53 binding","10/264","66/18352",3.32643140082569e-08,1.54812945578835e-06,1.07823816469628e-06,"CREBBP/GSK3B/SIRT1/SMARCB1/EP300/HIF1A/GATA1/TP53/CDK5/EHMT1",10]
["GO:0008013","beta-catenin binding","11/264","85/18352",3.69412685185734e-08,1.54812945578835e-06,1.07823816469628e-06,"GSK3B/ESR1/HDAC6/EP300/KDM6B/DVL3/CTNNB1/AR/MED12/PRKN/TCF4",11]
["GO:0031072","heat shock protein binding","13/264","127/18352",3.72482275076895e-08,1.54812945578835e-06,1.07823816469628e-06,"BAX/HDAC6/FKBP5/HIF1A/TSC2/BAG1/NR3C1/CREB1/CYP2E1/CDK5/PRKN/MAPT/HDAC2",13]
["GO:0005125","cytokine activity","17/264","235/18352",5.56810701063766e-08,2.17811244827885e-06,1.51700748277435e-06,"GRN/TGFB1/CCL2/IL2/IFNG/IL17A/VEGFA/IL1A/IL1B/LIF/IL6/IL10/IL18/CXCL8/ADIPOQ/IFNA1/TNF",17]
["GO:0004713","protein tyrosine kinase activity","13/264","135/18352",7.73686810647464e-08,2.85834293933647e-06,1.99077308002856e-06,"ERBB3/FGFR2/FGFR3/FGFR1/PDGFRB/PTK2B/MAP2K2/NTRK2/RET/MAP2K1/ALK/ERBB4/CSF1R",13]
["GO:0070851","growth factor receptor binding","13/264","141/18352",1.29482326480433e-07,4.53188142681516e-06,3.15635588096347e-06,"FGF8/IL2/VEGFA/PDGFRB/IL1A/IL1B/IL6/IL10/FGF17/IL6R/GDNF/PTEN/ERBB4",13]
["GO:0019199","transmembrane receptor protein kinase activity","10/264","80/18352",2.17556920305063e-07,7.23376760014335e-06,5.0381602596962e-06,"ERBB3/FGFR2/FGFR3/FGFR1/PDGFRB/NTRK2/RET/ALK/ERBB4/CSF1R",10]
["GO:0046906","tetrapyrrole binding","13/264","148/18352",2.28593361248147e-07,7.238789772858e-06,5.04165809269097e-06,"NOS2/PTGS2/CYP2D6/TPO/MTR/CYP2E1/IDO1/CYP27A1/CYP1A2/CYP3A4/NOS3/CYP2C19/CYP2B6",13]
["GO:0051427","hormone receptor binding","14/264","177/18352",2.86495881814468e-07,8.65998915484642e-06,6.03149224872564e-06,"GNAS/FUS/ESR1/SIRT1/EP300/HIF1A/PPARGC1A/VDR/GNRH1/CTNNB1/LEP/PTPN11/MED12/CCK",14]
["GO:0020037","heme binding","12/264","138/18352",7.47853079021052e-07,2.16227085890869e-05,1.50597416370372e-05,"NOS2/PTGS2/CYP2D6/TPO/CYP2E1/IDO1/CYP27A1/CYP1A2/CYP3A4/NOS3/CYP2C19/CYP2B6",12]
["GO:0019902","phosphatase binding","14/264","194/18352",8.72960670664301e-07,2.41882852496567e-05,1.68466094338725e-05,"DLG1/MAPK1/MAPK3/TSC2/TP53/SOD1/AKT1/SLC6A3/PIK3R1/VCP/CTNNB1/BCL2/CSF1R/MAPT",14]
["GO:0008395","steroid hydroxylase activity","7/264","38/18352",1.01509635366214e-06,2.70015630074128e-05,1.8805995604688e-05,"CYP2D6/CYP2E1/CYP27A1/CYP1A2/CYP3A4/CYP2C19/CYP2B6",7]
["GO:0017136","NAD-dependent histone deacetylase activity","5/264","15/18352",1.58316267355224e-06,4.04924299197015e-05,2.82020881118617e-05,"HDAC9/HDAC4/HDAC6/SIRT1/HDAC2",5]
["GO:0051879","Hsp90 protein binding","7/264","42/18352",2.06603381739029e-06,5.08856477246127e-05,3.54407360488003e-05,"HDAC6/HIF1A/TSC2/NR3C1/CYP2E1/CDK5/MAPT",7]
["GO:0034979","NAD-dependent protein deacetylase activity","5/264","16/18352",2.27577283660815e-06,5.40496048694437e-05,3.76443627108116e-05,"HDAC9/HDAC4/HDAC6/SIRT1/HDAC2",5]
["GO:0031490","chromatin DNA binding","10/264","106/18352",3.03316390360027e-06,6.95535860653166e-05,4.84425451028719e-05,"CREBBP/ZIC2/SMARCB1/EP300/GATA1/PPARGC1A/SRF/KDM6B/KDM6A/HDAC2",10]
["GO:0004712","protein serine/threonine/tyrosine kinase activity","7/264","45/18352",3.34969336115312e-06,7.42515361722275e-05,5.17145641721885e-05,"PRKACA/MAPK1/MAPK3/MAP2K2/AKT1/MAP2K1/LRRK2",7]
["GO:0008022","protein C-terminus binding","13/264","189/18352",3.67362983744319e-06,7.88052852225716e-05,5.48861503726656e-05,"DLG1/RBFOX1/SIRT1/EP300/OPRM1/PTK2B/ATF4/BRCA2/HESX1/CTNNB1/MAP2K1/MED12/TCF4",13]
["GO:0001046","core promoter sequence-specific DNA binding","7/264","46/18352",3.9027793955707e-06,8.11046343142035e-05,5.6487596514839e-05,"PAX6/REST/SMARCB1/TBP/NR3C1/TP53/FOS",7]
["GO:0016209","antioxidant activity","9/264","86/18352",4.02933338277696e-06,8.11971727135357e-05,5.65520474775714e-05,"PTGS2/SOD2/TPO/APOE/SOD1/ALB/NQO1/GPX1/HP",9]
["GO:0004708","MAP kinase kinase activity","5/264","18/18352",4.35996068475266e-06,8.36772967661747e-05,5.82793994097616e-05,"MAPK1/MAPK3/MAP2K2/MAP2K1/LRRK2",5]
["GO:0019838","growth factor binding","11/264","136/18352",4.41934307621166e-06,8.36772967661747e-05,5.82793994097616e-05,"NGFR/ERBB3/FGFR2/FGFR3/FGFR1/COL1A1/PDGFRB/DUSP1/COL2A1/NTRK2/IL6R",11]
["GO:0001102","RNA polymerase II activating transcription factor binding","7/264","47/18352",4.5298987723042e-06,8.36772967661747e-05,5.82793994097616e-05,"CREBBP/POU1F1/EP300/CREB1/CTNNB1/FOS/JUN",7]
["GO:0001091","RNA polymerase II general transcription initiation factor binding","5/264","19/18352",5.84775155741959e-06,0.000105101480694163,7.32008729805012e-05,"ESR1/TBP/TP53/AR/TCF4",5]
["GO:0008201","heparin binding","12/264","169/18352",6.2963199146668e-06,0.000108070195678059,7.52685177654866e-05,"COL11A1/FGFR2/FGFR1/APOB/ADA2/SFRP1/VEGFA/APOE/FBN1/LPL/F2/PTCH1",12]
["GO:0042826","histone deacetylase binding","10/264","115/18352",6.33795132548018e-06,0.000108070195678059,7.52685177654866e-05,"HDAC9/HDAC4/HDAC6/HIF1A/MAPK8/SRF/RAC1/TP53/PRKN/HDAC2",10]
["GO:0031078","histone deacetylase activity (H3-K14 specific)","4/264","10/18352",8.21207491916792e-06,0.000133195849298699,9.27679836825131e-05,"HDAC9/HDAC4/HDAC6/HDAC2",4]
["GO:0032041","NAD-dependent histone deacetylase activity (H3-K14 specific)","4/264","10/18352",8.21207491916792e-06,0.000133195849298699,9.27679836825131e-05,"HDAC9/HDAC4/HDAC6/HDAC2",4]
["GO:0016712","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","6/264","35/18352",9.57437198161269e-06,0.000151594223042201,0.000105582046915027,"CYP2D6/CYP2E1/CYP1A2/CYP3A4/CYP2C19/CYP2B6",6]
["GO:0051428","peptide hormone receptor binding","5/264","21/18352",9.99524052674149e-06,0.000154577556983328,0.00010765987348265,"GNAS/GNRH1/LEP/PTPN11/CCK",5]
["GO:0004497","monooxygenase activity","9/264","101/18352",1.51710459509899e-05,0.000229289671759279,0.000159695220536736,"NOS2/CYP2D6/CYP2E1/CYP27A1/CYP1A2/CYP3A4/NOS3/CYP2C19/CYP2B6",9]
["GO:0004674","protein serine/threonine kinase activity","19/264","435/18352",1.88296921007899e-05,0.000270783613042488,0.000188594839317285,"VRK2/PRKACA/GSK3B/MAPK1/MAPK3/MAPK8/PTK2B/PIK3CA/MAP2K2/AKT1/PLK2/BRAF/SQSTM1/PRKCI/CDK5/MAP2K1/PRKCE/LRRK2/MTOR",19]
["GO:1990841","promoter-specific chromatin binding","7/264","58/18352",1.89276060099791e-05,0.000270783613042488,0.000188594839317285,"HDAC4/GLI2/PPARGC1A/DNMT1/TP53/CHD7/HDAC2",7]
["GO:0008144","drug binding","9/264","104/18352",1.92259988258178e-05,0.000270783613042488,0.000188594839317285,"FKBP5/CYP2D6/HTR2A/SFRP1/CNR1/SLC6A3/DRD2/ACE/ALB",9]
["GO:0033613","activating transcription factor binding","8/264","80/18352",1.95452833474277e-05,0.000270783613042488,0.000188594839317285,"CREBBP/POU1F1/HDAC4/EP300/CREB1/CTNNB1/FOS/JUN",8]
["GO:0005496","steroid binding","9/264","106/18352",2.24131081386805e-05,0.000304177896167807,0.00021185322408205,"ESR1/TSPO/VDR/NR3C1/ESR2/NR3C2/CYP3A4/AR/PTCH1",9]
["GO:0016705","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","11/264","162/18352",2.33367189181232e-05,0.000310378361611039,0.000216171712083668,"NOS2/PTGS2/CYP2D6/CYP2E1/CYP27A1/CYP1A2/FTO/CYP3A4/NOS3/CYP2C19/CYP2B6",11]
["GO:0004407","histone deacetylase activity","5/264","25/18352",2.48966923015336e-05,0.000324633340794507,0.000226099992005672,"HDAC9/HDAC4/HDAC6/SIRT1/HDAC2",5]
["GO:0033558","protein deacetylase activity","5/264","26/18352",3.04640488443796e-05,0.000389588316952162,0.000271339706306215,"HDAC9/HDAC4/HDAC6/SIRT1/HDAC2",5]
["GO:0005539","glycosaminoglycan binding","13/264","232/18352",3.30758801816607e-05,0.000415008685298196,0.000289044434556718,"COL11A1/FGFR2/FGFR1/APOB/ADA2/SFRP1/VEGFA/APOE/SHH/FBN1/LPL/F2/PTCH1",13]
["GO:0140296","general transcription initiation factor binding","6/264","44/18352",3.73624836498027e-05,0.000460112067168866,0.000320457949433005,"ESR1/TBP/TP53/AR/TCF4/MTOR",6]
["GO:0016709","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","6/264","45/18352",4.25952206172871e-05,0.000505818244830285,0.000352291298338465,"NOS2/CYP2E1/CYP27A1/CYP3A4/NOS3/CYP2C19",6]
["GO:0048156","tau protein binding","6/264","45/18352",4.25952206172871e-05,0.000505818244830285,0.000352291298338465,"GSK3B/HDAC6/EP300/APOE/S100B/CDK5",6]
["GO:0035255","ionotropic glutamate receptor binding","5/264","28/18352",4.44577597775762e-05,0.000518673864071722,0.000361244954794709,"GNAS/FUS/DRD2/SQSTM1/PTEN",5]
["GO:0019903","protein phosphatase binding","10/264","149/18352",6.05558528523873e-05,0.000694304174945476,0.000483567608984581,"TP53/SOD1/AKT1/SLC6A3/PIK3R1/VCP/CTNNB1/BCL2/CSF1R/MAPT",10]
["GO:0005184","neuropeptide hormone activity","5/264","30/18352",6.2966670841158e-05,0.000709709086599492,0.000494296791616584,"OXT/NPY/NTS/PENK/CCK",5]
["GO:0005159","insulin-like growth factor receptor binding","4/264","16/18352",6.6482510875386e-05,0.000736847828868861,0.000513198329564383,"IGF1/GNAS/PIK3R1/INS",4]
["GO:0051721","protein phosphatase 2A binding","5/264","32/18352",8.69134455316314e-05,0.000947499037353031,0.000659912269782879,"TP53/AKT1/SLC6A3/BCL2/MAPT",5]
["GO:0070491","repressing transcription factor binding","7/264","74/18352",9.31723559207038e-05,0.000999348656246258,0.000696024390579111,"HDAC9/HDAC4/TBP/CTNNB1/BCL2/HDAC2/TLE1",7]
["GO:0004879","nuclear receptor activity","6/264","52/18352",9.78786484143707e-05,0.00101702033118057,0.000708332324051367,"ESR1/VDR/NR3C1/ESR2/NR3C2/AR",6]
["GO:0098531","ligand-activated transcription factor activity","6/264","52/18352",9.78786484143707e-05,0.00101702033118057,0.000708332324051367,"ESR1/VDR/NR3C1/ESR2/NR3C2/AR",6]
["GO:1901681","sulfur compound binding","13/264","262/18352",0.000114274234112426,0.00114721485326149,0.000799009949244253,"COL11A1/FGFR2/FGFR1/APOB/ADA2/SFRP1/VEGFA/APOE/GSTM1/FBN1/LPL/F2/PTCH1",13]
["GO:0003712","transcription coregulator activity","19/264","498/18352",0.000115429951738962,0.00114721485326149,0.000799009949244253,"CREBBP/BRCA1/HDAC9/ARID1B/HDAC4/FUS/SIRT1/SMARCB1/EP300/PPARGC1A/PER2/RERE/KMT2D/CTNNB1/MECP2/PAWR/MED12/PRKN/TLE1",19]
["GO:0071813","lipoprotein particle binding","5/264","34/18352",0.000117309188002679,0.00114721485326149,0.000799009949244253,"APOE/CRP/CDH13/LPL/MAPT",5]
["GO:0071814","protein-lipid complex binding","5/264","34/18352",0.000117309188002679,0.00114721485326149,0.000799009949244253,"APOE/CRP/CDH13/LPL/MAPT",5]
["GO:0051087","chaperone binding","8/264","104/18352",0.000129116192551604,0.00124438069633068,0.000866683824907793,"GRN/BAX/BAG1/TP53/SOD1/ALB/PRKN/MAPT",8]
["GO:0003713","transcription coactivator activity","13/264","267/18352",0.00013792053143244,0.00131024504860818,0.000912556899703366,"CREBBP/BRCA1/ARID1B/FUS/SIRT1/SMARCB1/EP300/PPARGC1A/PER2/RERE/KMT2D/CTNNB1/MED12",13]
["GO:0005507","copper ion binding","6/264","60/18352",0.000218674798626267,0.00201970473731205,0.00140667999116312,"ADNP/IL1A/TP53/SOD1/ALB/SNCG",6]
["GO:0097110","scaffold protein binding","6/264","60/18352",0.000218674798626267,0.00201970473731205,0.00140667999116312,"MAPK3/MAP2K2/BRAF/NOS3/MAP2K1/DLL1",6]
["GO:0035257","nuclear hormone receptor binding","9/264","144/18352",0.000241750202514934,0.00220224499551276,0.00153381527190441,"FUS/ESR1/SIRT1/EP300/HIF1A/PPARGC1A/VDR/CTNNB1/MED12",9]
["GO:0019213","deacetylase activity","5/264","41/18352",0.000291059012079849,0.0026145889677495,0.0018210037923384,"HDAC9/HDAC4/HDAC6/SIRT1/HDAC2",5]
["GO:0005158","insulin receptor binding","4/264","23/18352",0.0002988101677428,0.0026145889677495,0.0018210037923384,"IGF1/PIK3R1/PTPN11/INS",4]
["GO:0070412","R-SMAD binding","4/264","23/18352",0.0002988101677428,0.0026145889677495,0.0018210037923384,"PAX6/MEN1/FOS/JUN",4]
["GO:0032395","MHC class II receptor activity","3/264","10/18352",0.000327735626853712,0.00279415630586819,0.00194606849953621,"HLA-DQB1/HLA-DRB1/HLA-DQA1",3]
["GO:0043560","insulin receptor substrate binding","3/264","10/18352",0.000327735626853712,0.00279415630586819,0.00194606849953621,"PIK3CA/PIK3R1/PTPN11",3]
["GO:0000979","RNA polymerase II core promoter sequence-specific DNA binding","4/264","24/18352",0.000354541586236224,0.00298443233983657,0.00207859157820038,"PAX6/REST/TBP/FOS",4]
["GO:0070330","aromatase activity","4/264","25/18352",0.000417331089842832,0.00346906468431854,0.00241612736224797,"CYP2E1/CYP1A2/CYP3A4/CYP2C19",4]
["GO:0048407","platelet-derived growth factor binding","3/264","11/18352",0.000445851944782411,0.00357218726843739,0.00248794997722588,"COL1A1/PDGFRB/COL2A1",3]
["GO:0051400","BH domain binding","3/264","11/18352",0.000445851944782411,0.00357218726843739,0.00248794997722588,"BAX/BCL2L1/BCL2",3]
["GO:0070513","death domain binding","3/264","11/18352",0.000445851944782411,0.00357218726843739,0.00248794997722588,"BAX/BCL2L1/BCL2",3]
["GO:0003707","steroid hormone receptor activity","4/264","26/18352",0.000487670551842551,0.00386072520208686,0.00268891031091131,"ESR1/NR3C1/ESR2/NR3C2",4]
["GO:0035254","glutamate receptor binding","5/264","46/18352",0.000502153313777644,0.00392861121955451,0.00273619143111038,"GNAS/FUS/DRD2/SQSTM1/PTEN",5]
["GO:0005035","death receptor activity","3/264","12/18352",0.000588161968527994,0.00449572079392087,0.00313117079434141,"TNFRSF1B/NGFR/TNFRSF1A",3]
["GO:0005165","neurotrophin receptor binding","3/264","12/18352",0.000588161968527994,0.00449572079392087,0.00313117079434141,"NGF/PIK3R1/BDNF",3]
["GO:0035035","histone acetyltransferase binding","4/264","28/18352",0.000652989762751586,0.00493452491170233,0.00343678822500835,"PAX6/HIF1A/CREB1/TP53",4]
["GO:0016653","oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor","3/264","13/18352",0.000756503708067562,0.00565252770634752,0.0039368614021257,"NOS2/NOS3/NQO1",3]
["GO:0047485","protein N-terminus binding","7/264","107/18352",0.00090383810956033,0.00667835936508466,0.00465133062229878,"MEN1/TP53/SLC6A3/PDLIM5/HESX1/MAP2K1/MECP2",7]
["GO:0044548","S100 protein binding","3/264","14/18352",0.000952621596800228,0.00693684298322569,0.00483135878530954,"S100B/ATP2A2/AGER",3]
["GO:0046332","SMAD binding","6/264","79/18352",0.000967461778298714,0.00693684298322569,0.00483135878530954,"PAX6/MEN1/CTNNB1/FOS/TGIF1/JUN",6]
["GO:0051059","NF-kappaB binding","4/264","31/18352",0.000970114883368404,0.00693684298322569,0.00483135878530954,"GSK3B/EP300/CDKN2A/HDAC2",4]
["GO:0050661","NADP binding","5/264","54/18352",0.00105528819187991,0.00746560263404407,0.00519962826906116,"NOS2/LBR/SRD5A1/NOS3/MTHFR",5]
["GO:0005161","platelet-derived growth factor receptor binding","3/264","15/18352",0.00117816928940886,0.00824718502586205,0.00574398323922327,"VEGFA/PDGFRB/PTEN",3]
["GO:0051019","mitogen-activated protein kinase binding","4/264","33/18352",0.00123353450467343,0.00845670562482302,0.00588990973474021,"SIRT1/DUSP1/DUSP6/ACE",4]
["GO:0071855","neuropeptide receptor binding","4/264","33/18352",0.00123353450467343,0.00845670562482302,0.00588990973474021,"TAC1/GNAS/POMC/NTS",4]
["GO:0033218","amide binding","14/264","381/18352",0.0013027417806107,0.00884003351128686,0.00615688918870791,"NGFR/FOLH1/FKBP5/ADNP/OPRM1/GRPR/APOE/GSTM1/SRD5A1/PIK3R1/HLA-DQB1/HLA-DRB1/HLA-DQA1/AGER",14]
["GO:0042562","hormone binding","6/264","84/18352",0.00133295040876375,0.00895365678614035,0.0062360253041579,"TSPO/NR3C1/TTR/CDH13/PIK3R1/AR",6]
["GO:0008392","arachidonic acid epoxygenase activity","3/264","16/18352",0.00143471239214736,0.00954083740777991,0.00664498371099828,"CYP2E1/CYP2C19/CYP2B6",3]
["GO:0005506","iron ion binding","8/264","151/18352",0.00156200936774402,0.0102755627058562,0.00715670374448234,"CYP2D6/CYP2E1/CYP27A1/CYP1A2/FTO/CYP3A4/CYP2C19/CYP2B6",8]
["GO:0042054","histone methyltransferase activity","5/264","59/18352",0.00157610134736441,0.0102755627058562,0.00715670374448234,"KMT2A/PRMT7/MEN1/KMT2D/EHMT1",5]
["GO:0019825","oxygen binding","4/264","36/18352",0.00171678431874536,0.0108139735797729,0.00753169509315409,"CYP2E1/CYP3A4/ALB/CYP2C19",4]
["GO:0043394","proteoglycan binding","4/264","36/18352",0.00171678431874536,0.0108139735797729,0.00753169509315409,"ADA2/APOE/COL2A1/LPL",4]
["GO:0030275","LRR domain binding","3/264","17/18352",0.0017237311270014,0.0108139735797729,0.00753169509315409,"ATF4/KRAS/PAWR",3]
["GO:0050780","dopamine receptor binding","3/264","17/18352",0.0017237311270014,0.0108139735797729,0.00753169509315409,"GNAS/PPP1R1B/PTPN11",3]
["GO:0042277","peptide binding","12/264","308/18352",0.00175276476396789,0.0108933511031649,0.00758697979484379,"NGFR/FOLH1/ADNP/OPRM1/GRPR/APOE/GSTM1/PIK3R1/HLA-DQB1/HLA-DRB1/HLA-DQA1/AGER",12]
["GO:0003714","transcription corepressor activity","9/264","194/18352",0.00203434877573915,0.0125263142209864,0.00872430274196125,"CREBBP/HDAC9/HDAC4/SIRT1/RERE/MECP2/PAWR/PRKN/TLE1",9]
["GO:0032451","demethylase activity","4/264","38/18352",0.00210354545216383,0.0128335571164124,0.00893829067071062,"KDM6B/CYP1A2/FTO/KDM6A",4]
["GO:0046982","protein heterodimerization activity","12/264","321/18352",0.00246666063568929,0.0149120847521216,0.0103859395186918,"ERBB3/BAX/XBP1/HIF1A/SMC3/ATF4/TP53/PIK3R1/ATF3/BCL2L1/BCL2/TCF4",12]
["GO:0030020","extracellular matrix structural constituent conferring tensile strength","4/264","41/18352",0.00279043182303006,0.0161867749852164,0.0112737332702734,"COL11A1/COL1A1/COL2A1/COL11A2",4]
["GO:0004707","MAP kinase activity","3/264","20/18352",0.00279921672676674,0.0161867749852164,0.0112737332702734,"MAPK1/MAPK3/MAPK8",3]
["GO:0005123","death receptor binding","3/264","20/18352",0.00279921672676674,0.0161867749852164,0.0112737332702734,"NGF/FADD/BDNF",3]
["GO:0008391","arachidonic acid monooxygenase activity","3/264","20/18352",0.00279921672676674,0.0161867749852164,0.0112737332702734,"CYP2E1/CYP2C19/CYP2B6",3]
["GO:1990381","ubiquitin-specific protease binding","3/264","20/18352",0.00279921672676674,0.0161867749852164,0.0112737332702734,"VCP/PTEN/PRKN",3]
["GO:0030674","protein-macromolecule adaptor activity","10/264","244/18352",0.00289856169095851,0.0166118119558482,0.0115697621853157,"COL11A1/MAP2K2/MEN1/PIK3R1/MAP2K1/LPL/PTPN11/MAPT/LRRK2/COL11A2",10]
["GO:1990782","protein tyrosine kinase binding","6/264","98/18352",0.00292267969749509,0.0166118119558482,0.0115697621853157,"TP53/PIK3R1/SQSTM1/GDNF/PTEN/PTPN11",6]
["GO:0035591","signaling adaptor activity","5/264","68/18352",0.00295603027216999,0.016658984160958,0.0116026165901409,"MAP2K2/PIK3R1/MAP2K1/PTPN11/LRRK2",5]
["GO:0001784","phosphotyrosine residue binding","4/264","42/18352",0.00304978802600533,0.0167612317131698,0.0116738297646137,"MAPK1/MAPK3/PIK3R1/PTPN11",4]
["GO:0030331","estrogen receptor binding","4/264","42/18352",0.00304978802600533,0.0167612317131698,0.0116738297646137,"FUS/ESR1/PPARGC1A/CTNNB1",4]
["GO:0030544","Hsp70 protein binding","4/264","42/18352",0.00304978802600533,0.0167612317131698,0.0116738297646137,"BAX/CREB1/CYP2E1/PRKN",4]
["GO:0016811","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","5/264","69/18352",0.00315023983178085,0.0171713892470022,0.0119594954787194,"HDAC9/HDAC4/HDAC6/SIRT1/HDAC2",5]
["GO:0050750","low-density lipoprotein particle receptor binding","3/264","21/18352",0.00323132218533073,0.0174701565304466,0.0121675803298718,"APOB/APOE/CRP",3]
["GO:0016922","nuclear receptor binding","6/264","101/18352",0.00339589814599579,0.018211873121671,0.0126841696454851,"FUS/ESR1/EP300/PPARGC1A/VDR/CTNNB1",6]
["GO:0018024","histone-lysine N-methyltransferase activity","4/264","44/18352",0.00361691640843045,0.01924199529285,0.0134016271133423,"KMT2A/MEN1/KMT2D/EHMT1",4]
["GO:0001098","basal transcription machinery binding","5/264","72/18352",0.00378798503657545,0.0196797660103334,0.013706524803398,"ESR1/TBP/TP53/AR/TCF4",5]
["GO:0001099","basal RNA polymerase II transcription machinery binding","5/264","72/18352",0.00378798503657545,0.0196797660103334,0.013706524803398,"ESR1/TBP/TP53/AR/TCF4",5]
["GO:0030971","receptor tyrosine kinase binding","5/264","72/18352",0.00378798503657545,0.0196797660103334,0.013706524803398,"TP53/PIK3R1/SQSTM1/GDNF/PTPN11",5]
["GO:0019207","kinase regulator activity","9/264","216/18352",0.00415937687970565,0.0214417490310408,0.0149337072792369,"ERBB3/PRKAR1A/IL2/PIK3CA/MAP2K2/PPP1R1B/PIK3R1/CDKN2A/MAP2K1",9]
["GO:0017134","fibroblast growth factor binding","3/264","23/18352",0.00421260775228668,0.0215491088866972,0.0150084810607785,"FGFR2/FGFR3/FGFR1",3]
["GO:0032813","tumor necrosis factor receptor superfamily binding","4/264","48/18352",0.00495755064727086,0.025166192217062,0.0175277001590934,"NGF/FADD/BDNF/TNF",4]
["GO:0070325","lipoprotein particle receptor binding","3/264","26/18352",0.00599151375235227,0.0301845200402595,0.0210228552714115,"APOB/APOE/CRP",3]
["GO:0001221","transcription cofactor binding","4/264","51/18352",0.00615730851076046,0.0305567922362366,0.0212821346797691,"ESR1/CREB1/PER2/AR",4]
["GO:0051018","protein kinase A binding","4/264","51/18352",0.00615730851076046,0.0305567922362366,0.0212821346797691,"PRKACA/GSK3B/PRKAR1A/LRRK2",4]
["GO:0060090","molecular adaptor activity","11/264","316/18352",0.00624451986417859,0.0305671567805985,0.0212893533572827,"COL11A1/DLG1/MAP2K2/MEN1/PIK3R1/MAP2K1/LPL/PTPN11/MAPT/LRRK2/COL11A2",11]
["GO:0035258","steroid hormone receptor binding","5/264","81/18352",0.0062513283040021,0.0305671567805985,0.0212893533572827,"FUS/ESR1/EP300/PPARGC1A/CTNNB1",5]
["GO:0045309","protein phosphorylated amino acid binding","4/264","53/18352",0.00705584250392761,0.0342491625190647,0.0238537894869624,"MAPK1/MAPK3/PIK3R1/PTPN11",4]
["GO:0051219","phosphoprotein binding","5/264","85/18352",0.00764241273554124,0.0368275686169197,0.0256495927050965,"MAPK1/MAPK3/PIK3R1/PTPN11/MTOR",5]
["GO:0005080","protein kinase C binding","4/264","55/18352",0.00803694681076523,0.0382055105037372,0.0266092989658003,"HDAC9/AKT1/SQSTM1/PDLIM5",4]
["GO:0016810","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds","6/264","121/18352",0.00813045742053316,0.0382055105037372,0.0266092989658003,"HDAC9/HDAC4/ADA2/HDAC6/SIRT1/HDAC2",6]
["GO:0001223","transcription coactivator binding","3/264","29/18352",0.00815816916019651,0.0382055105037372,0.0266092989658003,"ESR1/CREB1/AR",3]
["GO:0043425","bHLH transcription factor binding","3/264","29/18352",0.00815816916019651,0.0382055105037372,0.0266092989658003,"CREBBP/SIRT1/TCF4",3]
["GO:0008757","S-adenosylmethionine-dependent methyltransferase activity","7/264","160/18352",0.00853301419099621,0.0386274215509535,0.0269031507438378,"COMT/KMT2A/DNMT1/PRMT7/MEN1/KMT2D/EHMT1",7]
["GO:0005031","tumor necrosis factor-activated receptor activity","2/264","10/18352",0.00859677953314453,0.0386274215509535,0.0269031507438378,"TNFRSF1B/TNFRSF1A",2]
["GO:0008330","protein tyrosine/threonine phosphatase activity","2/264","10/18352",0.00859677953314453,0.0386274215509535,0.0269031507438378,"DUSP1/DUSP6",2]
["GO:0016595","glutamate binding","2/264","10/18352",0.00859677953314453,0.0386274215509535,0.0269031507438378,"GCLC/GLUL",2]
["GO:0016725","oxidoreductase activity, acting on CH or CH2 groups","2/264","10/18352",0.00859677953314453,0.0386274215509535,0.0269031507438378,"CYP1A2/CYP3A4",2]
["GO:0030957","Tat protein binding","2/264","10/18352",0.00859677953314453,0.0386274215509535,0.0269031507438378,"SMARCB1/DLL1",2]
["GO:0019209","kinase activator activity","5/264","89/18352",0.00923561043433994,0.0412193351599735,0.0287083616468356,"ERBB3/IL2/PIK3CA/MAP2K2/MAP2K1",5]
["GO:0042605","peptide antigen binding","3/264","31/18352",0.00982678348906491,0.0435654068015211,0.0303423490188671,"HLA-DQB1/HLA-DRB1/HLA-DQA1",3]
["GO:0008276","protein methyltransferase activity","5/264","91/18352",0.0101121659318067,0.04408525067119,0.0307044088568637,"KMT2A/PRMT7/MEN1/KMT2D/EHMT1",5]
["GO:0051213","dioxygenase activity","5/264","91/18352",0.0101121659318067,0.04408525067119,0.0307044088568637,"PTGS2/IDO1/KDM6B/FTO/KDM6A",5]
["GO:0016597","amino acid binding","4/264","59/18352",0.0102584103879472,0.04408525067119,0.0307044088568637,"GCLC/NOS2/GLUL/NOS3",4]
["GO:0005078","MAP-kinase scaffold activity","2/264","11/18352",0.0104080967750028,0.04408525067119,0.0307044088568637,"MAP2K2/MAP2K1",2]
["GO:0005527","macrolide binding","2/264","11/18352",0.0104080967750028,0.04408525067119,0.0307044088568637,"FKBP5/ALB",2]
["GO:0008503","benzodiazepine receptor activity","2/264","11/18352",0.0104080967750028,0.04408525067119,0.0307044088568637,"GABRA3/TSPO",2]
["GO:0043522","leucine zipper domain binding","2/264","11/18352",0.0104080967750028,0.04408525067119,0.0307044088568637,"ATF4/PAWR",2]
["GO:0003779","actin binding","13/264","437/18352",0.0109790783743276,0.046209412145113,0.0321838406709137,"HDAC6/SYNE1/FLNB/PDLIM5/NOS3/INPPL1/PRKCE/PAWR/NEB/PRKN/MAPT/LRRK2/DMD",13]
["GO:0016279","protein-lysine N-methyltransferase activity","4/264","61/18352",0.0115041406727681,0.0481148021848477,0.0335109029858852,"KMT2A/MEN1/KMT2D/EHMT1",4]
["GO:0016278","lysine N-methyltransferase activity","4/264","62/18352",0.0121618493303196,0.0505476862791407,0.0352053533246093,"KMT2A/MEN1/KMT2D/EHMT1",4]
["GO:0034452","dynactin binding","2/264","12/18352",0.0123720837362977,0.0507866400286295,0.0353717793630344,"GSK3B/MAPT",2]
["GO:0070410","co-SMAD binding","2/264","12/18352",0.0123720837362977,0.0507866400286295,0.0353717793630344,"PAX6/TGIF1",2]
["GO:0000217","DNA secondary structure binding","3/264","34/18352",0.0126760833311746,0.0517153092958965,0.0360185771115069,"KMT2A/MEN1/MAPT",3]
["GO:0008168","methyltransferase activity","8/264","218/18352",0.0138368596983398,0.0561067786548533,0.0390771390710494,"COMT/MTR/KMT2A/DNMT1/PRMT7/MEN1/KMT2D/EHMT1",8]
["GO:0003684","damaged DNA binding","4/264","65/18352",0.0142777848999301,0.0569932834688348,0.039694570203858,"CREBBP/BRCA1/EP300/REV1",4]
["GO:0017017","MAP kinase tyrosine/serine/threonine phosphatase activity","2/264","13/18352",0.0144840073777941,0.0569932834688348,0.039694570203858,"DUSP1/DUSP6",2]
["GO:0031434","mitogen-activated protein kinase kinase binding","2/264","13/18352",0.0144840073777941,0.0569932834688348,0.039694570203858,"DLG1/ACE",2]
["GO:0034236","protein kinase A catalytic subunit binding","2/264","13/18352",0.0144840073777941,0.0569932834688348,0.039694570203858,"GSK3B/PRKAR1A",2]
["GO:1900750","oligopeptide binding","2/264","13/18352",0.0144840073777941,0.0569932834688348,0.039694570203858,"FOLH1/GSTM1",2]
["GO:0008170","N-methyltransferase activity","5/264","100/18352",0.0147646647733149,0.0577558945544376,0.0402257120759043,"KMT2A/PRMT7/MEN1/KMT2D/EHMT1",5]
["GO:0042056","chemoattractant activity","3/264","37/18352",0.0159498704325913,0.0616666502190304,0.0429494675051419,"FGF8/VEGFA/GDNF",3]
["GO:0048487","beta-tubulin binding","3/264","37/18352",0.0159498704325913,0.0616666502190304,0.0429494675051419,"HDAC6/ADNP/SMC3",3]
["GO:0033549","MAP kinase phosphatase activity","2/264","14/18352",0.0167392383412931,0.0636091056969137,0.0443023450837231,"DUSP1/DUSP6",2]
["GO:0035497","cAMP response element binding","2/264","14/18352",0.0167392383412931,0.0636091056969137,0.0443023450837231,"CREB1/JUN",2]
["GO:1901338","catecholamine binding","2/264","14/18352",0.0167392383412931,0.0636091056969137,0.0443023450837231,"SLC6A3/DRD2",2]
["GO:0019887","protein kinase regulator activity","7/264","185/18352",0.017812686392571,0.067303616199203,0.0468754905067658,"ERBB3/PRKAR1A/PIK3CA/MAP2K2/PPP1R1B/CDKN2A/MAP2K1",7]
["GO:0016741","transferase activity, transferring one-carbon groups","8/264","229/18352",0.0180779542256245,0.0679199975143518,0.0473047865553064,"COMT/MTR/KMT2A/DNMT1/PRMT7/MEN1/KMT2D/EHMT1",8]
["GO:0016805","dipeptidase activity","2/264","15/18352",0.0191332489646599,0.0706867253416602,0.0492317517219319,"FOLH1/ACE",2]
["GO:0043274","phospholipase binding","2/264","15/18352",0.0191332489646599,0.0706867253416602,0.0492317517219319,"PTPN11/PRKN",2]
["GO:0070742","C2H2 zinc finger domain binding","2/264","15/18352",0.0191332489646599,0.0706867253416602,0.0492317517219319,"GATA1/EHMT1",2]
["GO:0030159","signaling receptor complex adaptor activity","3/264","41/18352",0.0209861078103106,0.0758156396625659,0.0528039279011144,"PIK3R1/PTPN11/LRRK2",3]
["GO:0042169","SH2 domain binding","3/264","41/18352",0.0209861078103106,0.0758156396625659,0.0528039279011144,"FGFR1/SQSTM1/INPPL1",3]
["GO:0004697","protein kinase C activity","2/264","16/18352",0.0216616113321617,0.0758156396625659,0.0528039279011144,"PRKCI/PRKCE",2]
["GO:0004698","calcium-dependent protein kinase C activity","2/264","16/18352",0.0216616113321617,0.0758156396625659,0.0528039279011144,"PRKCI/PRKCE",2]
["GO:0005149","interleukin-1 receptor binding","2/264","16/18352",0.0216616113321617,0.0758156396625659,0.0528039279011144,"IL1A/IL1B",2]
["GO:0005521","lamin binding","2/264","16/18352",0.0216616113321617,0.0758156396625659,0.0528039279011144,"SYNE1/LBR",2]
["GO:0010181","FMN binding","2/264","16/18352",0.0216616113321617,0.0758156396625659,0.0528039279011144,"NOS2/NOS3",2]
["GO:0043395","heparan sulfate proteoglycan binding","2/264","16/18352",0.0216616113321617,0.0758156396625659,0.0528039279011144,"APOE/LPL",2]
["GO:0070402","NADPH binding","2/264","16/18352",0.0216616113321617,0.0758156396625659,0.0528039279011144,"LBR/SRD5A1",2]
["GO:0071837","HMG box domain binding","2/264","16/18352",0.0216616113321617,0.0758156396625659,0.0528039279011144,"PAX6/JUN",2]
["GO:0030594","neurotransmitter receptor activity","5/264","111/18352",0.0221652677128518,0.0771722671677825,0.0537487891631568,"GABRA3/TSPO/HTR2A/PTK2B/DRD2",5]
["GO:0140030","modification-dependent protein binding","6/264","153/18352",0.0234514119886145,0.0812249425647326,0.0565713885690262,"ATRX/HDAC6/L3MBTL2/KMT2A/SQSTM1/VCP",6]
["GO:0030169","low-density lipoprotein particle binding","2/264","17/18352",0.0243199953595164,0.082937420072197,0.0577640915421712,"CRP/CDH13",2]
["GO:0034185","apolipoprotein binding","2/264","17/18352",0.0243199953595164,0.082937420072197,0.0577640915421712,"LPL/MAPT",2]
["GO:0042800","histone methyltransferase activity (H3-K4 specific)","2/264","17/18352",0.0243199953595164,0.082937420072197,0.0577640915421712,"KMT2A/KMT2D",2]
["GO:0005245","voltage-gated calcium channel activity","3/264","44/18352",0.0252702398916892,0.0857383139182313,0.0597148525904579,"OPRM1/CNR1/CDK5",3]
["GO:0008138","protein tyrosine/serine/threonine phosphatase activity","3/264","45/18352",0.026794856487488,0.0899928260817147,0.062678026871317,"DUSP1/DUSP6/PTEN",3]
["GO:0008188","neuropeptide receptor activity","3/264","45/18352",0.026794856487488,0.0899928260817147,0.062678026871317,"OPRM1/GRPR/SORCS3",3]
["GO:0046965","retinoid X receptor binding","2/264","18/18352",0.0271041669130632,0.0905742261165177,0.0630829592263835,"FUS/VDR",2]
["GO:0030295","protein kinase activator activity","4/264","82/18352",0.0305820313617234,0.10168525427773,0.0708215463113594,"ERBB3/PIK3CA/MAP2K2/MAP2K1",4]
["GO:0031683","G-protein beta/gamma-subunit complex binding","2/264","20/18352",0.0330334047664425,0.108748584998437,0.0757410010277994,"GNAS/GNAL",2]
["GO:0120020","cholesterol transfer activity","2/264","20/18352",0.0330334047664425,0.108748584998437,0.0757410010277994,"APOB/APOE",2]
["GO:0031406","carboxylic acid binding","7/264","212/18352",0.034059426282947,0.111573982651033,0.0777088284391841,"GCLC/NOS2/VDR/GLUL/ALB/NOS3/ADIPOQ",7]
["GO:0030165","PDZ domain binding","4/264","85/18352",0.0342576543895985,0.111673236122956,0.077777956302494,"MAP2K2/PTEN/FZD2/PRKN",4]
["GO:0005201","extracellular matrix structural constituent","6/264","169/18352",0.0356960370208268,0.115794461555365,0.0806482993025099,"COL11A1/COL1A1/COL2A1/FBN1/ADIPOQ/COL11A2",6]
["GO:0120015","sterol transfer activity","2/264","21/18352",0.0361704660907701,0.116763883254185,0.0813234802245214,"APOB/APOE",2]
["GO:0031593","polyubiquitin modification-dependent protein binding","3/264","51/18352",0.0369488901818992,0.118700540922527,0.0826723197560929,"HDAC6/SQSTM1/VCP",3]
["GO:0004601","peroxidase activity","3/264","52/18352",0.0388072032662094,0.124071106596294,0.086412800795203,"PTGS2/TPO/GPX1",3]
["GO:0015631","tubulin binding","10/264","365/18352",0.0390508994748494,0.12425286196543,0.0865393894179488,"BRCA1/HDAC6/ADNP/SMC3/PPARGC1A/STMN1/BRCA2/PRKN/MAPT/LRRK2",10]
["GO:0050321","tau-protein kinase activity","2/264","22/18352",0.0394173014583299,0.124821454618045,0.0869354017126072,"GSK3B/CDK5",2]
["GO:0017124","SH3 domain binding","5/264","131/18352",0.0410125584309513,0.12925758936769,0.0900250721357872,"ADAM10/INPPL1/PRKN/MAPT/GPX1",5]
["GO:0044325","ion channel binding","5/264","132/18352",0.0421481184173248,0.132209899752457,0.0920812914777701,"DLG1/TSPO/CTNNB1/ATP2A2/LRRK2",5]
["GO:0009931","calcium-dependent protein serine/threonine kinase activity","2/264","23/18352",0.042770129430334,0.132907177902673,0.0925669303952137,"PRKCI/PRKCE",2]
["GO:0070840","dynein complex binding","2/264","23/18352",0.042770129430334,0.132907177902673,0.0925669303952137,"HDAC6/SMC3",2]
["GO:0043177","organic acid binding","7/264","224/18352",0.0437022924981341,0.135172207029113,0.094144473435393,"GCLC/NOS2/VDR/GLUL/ALB/NOS3/ADIPOQ",7]
["GO:0004402","histone acetyltransferase activity","3/264","55/18352",0.0446615429850552,0.137499657801211,0.09576549178082,"CREBBP/EP300/BRCA2",3]
["GO:0004721","phosphoprotein phosphatase activity","6/264","179/18352",0.0451143566380443,0.1382536735682,0.0962906472022289,"DLG1/DUSP1/DUSP6/PTEN/PTPN11/LRRK2",6]
["GO:0008327","methyl-CpG binding","2/264","24/18352",0.0462252539183896,0.140364355505612,0.0977606908151474,"DNMT1/MECP2",2]
["GO:0010857","calcium-dependent protein kinase activity","2/264","24/18352",0.0462252539183896,0.140364355505612,0.0977606908151474,"PRKCI/PRKCE",2]
["GO:0016684","oxidoreductase activity, acting on peroxide as acceptor","3/264","56/18352",0.0467050614603991,0.141176663050752,0.0983264451797875,"PTGS2/TPO/GPX1",3]
["GO:0050840","extracellular matrix binding","3/264","57/18352",0.0487940344795556,0.146162310490561,0.101798839122828,"COL11A1/VEGFA/SHH",3]
["GO:0061733","peptide-lysine-N-acetyltransferase activity","3/264","57/18352",0.0487940344795556,0.146162310490561,0.101798839122828,"CREBBP/EP300/BRCA2",3]
["GO:0003887","DNA-directed DNA polymerase activity","2/264","25/18352",0.0497790625268126,0.147124784801469,0.102469181341743,"REV1/POLG",2]
["GO:0005104","fibroblast growth factor receptor binding","2/264","25/18352",0.0497790625268126,0.147124784801469,0.102469181341743,"FGF8/FGF17",2]
["GO:0016702","oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","2/264","25/18352",0.0497790625268126,0.147124784801469,0.102469181341743,"PTGS2/IDO1",2]
["ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"]
["hsa04010","MAPK signaling pathway","42/221","294/8223",1.14687242592052e-19,2.44545910021103e-17,7.82622345546619e-18,"IGF1/NGFR/ERBB3/FGFR2/TNFRSF1A/FGFR3/PRKACA/FGFR1/MAPK1/MAPK3/TGFB1/MAPK8/FGF8/SRF/VEGFA/PDGFRB/IL1A/STMN1/DUSP1/IL1B/MAP2K2/ATF4/KRAS/NGF/FLNB/RAC1/DUSP6/TP53/AKT1/NTRK2/BRAF/FGF17/MAP2K1/FOS/BDNF/JUN/ERBB4/CSF1R/MAPT/NF1/TNF/INS",42]
["hsa01521","EGFR tyrosine kinase inhibitor resistance","24/221","79/8223",1.79154512835973e-19,2.44545910021103e-17,7.82622345546619e-18,"IGF1/ERBB3/FGFR2/FGFR3/GSK3B/BAX/MAPK1/MAPK3/VEGFA/PDGFRB/PIK3CA/MAP2K2/KRAS/IL6/AKT1/PIK3R1/BRAF/IL6R/MAP2K1/BCL2L1/BCL2/PTEN/NF1/MTOR",24]
["hsa05215","Prostate cancer","25/221","97/8223",2.59083746740355e-18,1.88827623183467e-16,6.04306640610285e-17,"CREBBP/IGF1/FGFR2/FGFR1/GSK3B/MAPK1/EP300/MAPK3/PDGFRB/CREB1/PIK3CA/MAP2K2/ATF4/KRAS/TP53/AKT1/PIK3R1/BRAF/CTNNB1/MAP2K1/AR/BCL2/PTEN/MTOR/INS",25]
["hsa01522","Endocrine resistance","25/221","98/8223",3.39769007679277e-18,1.88827623183467e-16,6.04306640610285e-17,"IGF1/PRKACA/NOTCH3/BAX/GNAS/ESR1/MAPK1/CYP2D6/MAPK3/MAPK8/PIK3CA/MAP2K2/KRAS/ESR2/TP53/AKT1/PIK3R1/CDKN2A/BRAF/MAP2K1/FOS/BCL2/JUN/DLL1/MTOR",25]
["hsa04151","PI3K-Akt signaling pathway","44/221","354/8223",3.45838137698657e-18,1.88827623183467e-16,6.04306640610285e-17,"BRCA1/IGF1/NGFR/ERBB3/FGFR2/FGFR3/FGFR1/GSK3B/MAPK1/MAPK3/TSC2/FGF8/COL1A1/IL2/GNB3/VEGFA/PDGFRB/CREB1/PIK3CA/MAP2K2/ATF4/KRAS/NGF/RAC1/IL6/COL2A1/TP53/AKT1/PIK3R1/NTRK2/FGF17/IL6R/NOS3/MAP2K1/BCL2L1/BCL2/PTEN/PRL/BDNF/ERBB4/CSF1R/IFNA1/MTOR/INS",44]
["hsa05224","Breast cancer","29/221","147/8223",1.19707959020022e-17,5.44671213541098e-16,1.74311589450207e-16,"BRCA1/IGF1/NOTCH3/FGFR1/GSK3B/BAX/ESR1/MAPK1/MAPK3/FGF8/PIK3CA/MAP2K2/KRAS/BRCA2/ESR2/TP53/AKT1/PIK3R1/BRAF/FGF17/DVL3/CTNNB1/MAP2K1/FOS/PTEN/JUN/FZD2/DLL1/MTOR",29]
["hsa05166","Human T-cell leukemia virus 1 infection","33/221","222/8223",4.37770434652984e-16,1.70730469514664e-14,5.46390166559363e-15,"CREBBP/TNFRSF1A/PRKACA/DLG1/BAX/MAPK1/TSPO/EP300/MAPK3/TGFB1/MAPK8/IL2/TBP/SRF/CREB1/PIK3CA/MAP2K2/ATF4/KRAS/IL6/TP53/AKT1/PIK3R1/CDKN2A/MAP2K1/FOS/BCL2L1/PTEN/JUN/HLA-DQB1/HLA-DRB1/HLA-DQA1/TNF",33]
["hsa05163","Human cytomegalovirus infection","33/221","225/8223",6.59156015302809e-16,2.24936990222084e-14,7.19867753554384e-15,"TNFRSF1A/PRKACA/PTGS2/GSK3B/BAX/GNAS/MAPK1/MAPK3/TSC2/CCL2/GNB3/VEGFA/CREB1/PTK2B/PIK3CA/IL1B/MAP2K2/ATF4/KRAS/RAC1/IL6/TP53/AKT1/PIK3R1/CDKN2A/IL6R/CTNNB1/FADD/MAP2K1/CXCL8/IFNA1/MTOR/TNF",33]
["hsa04933","AGE-RAGE signaling pathway in diabetic complications","23/221","100/8223",9.6424108192971e-16,2.92486461518679e-14,9.36046898247555e-15,"BAX/MAPK1/MAPK3/TGFB1/MAPK8/CCL2/COL1A1/VEGFA/IL1A/PIK3CA/IL1B/KRAS/RAC1/IL6/AKT1/PIK3R1/NOS3/CXCL8/PRKCE/BCL2/JUN/AGER/TNF",23]
["hsa05142","Chagas disease","23/221","102/8223",1.5379207974318e-15,4.19852377698882e-14,1.34365711775621e-14,"NOS2/TNFRSF1A/GNAS/MAPK1/MAPK3/TGFB1/MAPK8/CCL2/IL2/IFNG/PIK3CA/IL1B/IL6/IL10/GNAL/AKT1/PIK3R1/ACE/FADD/CXCL8/FOS/JUN/TNF",23]
["hsa05210","Colorectal cancer","21/221","86/8223",4.95495429611204e-15,1.2297295662169e-13,3.93551393853875e-14,"GSK3B/BAX/MAPK1/MAPK3/TGFB1/MAPK8/PIK3CA/MAP2K2/KRAS/RAC1/TP53/AKT1/PIK3R1/BRAF/CTNNB1/MAP2K1/FOS/BCL2/JUN/DCC/MTOR",21]
["hsa05205","Proteoglycans in cancer","30/221","205/8223",1.65782921304372e-14,3.77156145967446e-13,1.20701600598797e-13,"IGF1/ERBB3/PRKACA/FGFR1/ESR1/MAPK1/HIF1A/MAPK3/TGFB1/COL1A1/VEGFA/PIK3CA/MAP2K2/KRAS/FLNB/RAC1/TP53/AKT1/PIK3R1/BRAF/SHH/CTNNB1/MAP2K1/ERBB4/PTPN11/FZD2/PTCH1/MTOR/TNF/TWIST2",30]
["hsa05167","Kaposi sarcoma-associated herpesvirus infection","29/221","194/8223",2.67328792517031e-14,5.61390464285765e-13,1.79662265416304e-13,"CREBBP/TNFRSF1A/PTGS2/GSK3B/BAX/MAPK1/EP300/HIF1A/MAPK3/MAPK8/GNB3/VEGFA/CREB1/PIK3CA/MAP2K2/KRAS/RAC1/IL6/TP53/AKT1/PIK3R1/CTNNB1/FADD/MAP2K1/CXCL8/FOS/JUN/IFNA1/MTOR",29]
["hsa05417","Lipid and atherosclerosis","30/221","215/8223",6.11906588694718e-14,1.1932178479547e-12,3.81866517756854e-13,"TNFRSF1A/GSK3B/APOB/BAX/MAPK1/XBP1/MAPK3/MAPK8/CCL2/SOD2/PIK3CA/IL1B/ATF4/KRAS/RAC1/IL6/TP53/AKT1/PIK3R1/IL18/NOS3/CXCL8/FOS/BCL2L1/BCL2/JUN/CYP2B6/IFNA1/AGER/TNF",30]
["hsa05161","Hepatitis B","26/221","162/8223",1.14842058297204e-13,2.09012546100911e-12,6.68904620257398e-13,"CREBBP/BAX/MAPK1/EP300/MAPK3/TGFB1/MAPK8/CREB1/PTK2B/PIK3CA/MAP2K2/ATF4/KRAS/IL6/TP53/AKT1/PIK3R1/BRAF/FADD/MAP2K1/CXCL8/FOS/BCL2/JUN/IFNA1/TNF",26]
["hsa05230","Central carbon metabolism in cancer","18/221","70/8223",1.80642370471841e-13,3.0822104461758e-12,9.86402417708082e-13,"FGFR2/FGFR3/FGFR1/MAPK1/HIF1A/MAPK3/PDGFRB/PIK3CA/MAP2K2/KRAS/LDHA/TP53/AKT1/PIK3R1/RET/MAP2K1/PTEN/MTOR",18]
["hsa05218","Melanoma","18/221","72/8223",3.07674135516266e-13,4.94088464682003e-12,1.58123549522291e-12,"IGF1/FGFR1/BAX/MAPK1/MAPK3/FGF8/PDGFRB/PIK3CA/MAP2K2/KRAS/TP53/AKT1/PIK3R1/CDKN2A/BRAF/FGF17/MAP2K1/PTEN",18]
["hsa05165","Human papillomavirus infection","36/221","331/8223",3.7516673350162e-13,5.69002879144123e-12,1.82098472986166e-12,"CREBBP/TNFRSF1A/PRKACA/PTGS2/NOTCH3/DLG1/GSK3B/BAX/GNAS/MAPK1/EP300/MAPK3/TSC2/COL1A1/TBP/VEGFA/PDGFRB/CREB1/PIK3CA/MAP2K2/KRAS/COL2A1/TP53/AKT1/PIK3R1/DVL3/PRKCI/CTNNB1/FADD/MAP2K1/PTEN/FZD2/HDAC2/IFNA1/MTOR/TNF",36]
["hsa04722","Neurotrophin signaling pathway","22/221","119/8223",5.11032893886261e-13,7.34273579110259e-12,2.3499019497263e-12,"NGFR/GSK3B/BAX/MAPK1/MAPK3/MAPK8/PIK3CA/MAP2K2/ATF4/KRAS/NGF/RAC1/TP53/AKT1/PIK3R1/NTRK2/BRAF/MAP2K1/BCL2/BDNF/JUN/PTPN11",22]
["hsa04919","Thyroid hormone signaling pathway","22/221","121/8223",7.29493272888011e-13,9.90483072269405e-12,3.16985135910394e-12,"CREBBP/PRKACA/NOTCH3/GSK3B/ESR1/MAPK1/EP300/HIF1A/MAPK3/TSC2/PIK3CA/MAP2K2/KRAS/TP53/AKT1/PIK3R1/CTNNB1/MAP2K1/ATP2A2/MED12/HDAC2/MTOR",22]
["hsa04066","HIF-1 signaling pathway","21/221","109/8223",7.6191005559185e-13,9.90483072269405e-12,3.16985135910394e-12,"CREBBP/NOS2/IGF1/MAPK1/EP300/HIF1A/MAPK3/IFNG/VEGFA/PIK3CA/MAP2K2/LDHA/IL6/AKT1/PIK3R1/IL6R/NOS3/MAP2K1/BCL2/MTOR/INS",21]
["hsa05212","Pancreatic cancer","18/221","76/8223",8.45984167158636e-13,1.04978944379231e-11,3.35965004182616e-12,"BAX/MAPK1/MAPK3/TGFB1/MAPK8/VEGFA/PIK3CA/KRAS/RAC1/BRCA2/TP53/AKT1/PIK3R1/CDKN2A/BRAF/MAP2K1/BCL2L1/MTOR",18]
["hsa05207","Chemical carcinogenesis - receptor activation","28/221","212/8223",1.80509542799942e-12,2.12149708403769e-11,6.78944507326503e-12,"PRKACA/GNAS/ESR1/MAPK1/MAPK3/FGF8/VDR/VEGFA/CREB1/PIK3CA/MAP2K2/ATF4/KRAS/GSTM1/ESR2/CYP1A2/AKT1/PIK3R1/FGF17/CYP3A4/MAP2K1/AR/FOS/BCL2/JUN/CYP2B6/DLL1/MTOR",28]
["hsa05211","Renal cell carcinoma","17/221","69/8223",1.8650523815716e-12,2.12149708403769e-11,6.78944507326503e-12,"CREBBP/MAPK1/EP300/HIF1A/MAPK3/TGFB1/VEGFA/PIK3CA/MAP2K2/KRAS/RAC1/AKT1/PIK3R1/BRAF/MAP2K1/JUN/PTPN11",17]
["hsa04014","Ras signaling pathway","29/221","236/8223",4.44800622584919e-12,4.85722279862732e-11,1.55446112313887e-11,"IGF1/NGFR/FGFR2/FGFR3/PRKACA/FGFR1/MAPK1/MAPK3/MAPK8/FGF8/GNB3/VEGFA/PDGFRB/PIK3CA/MAP2K2/KRAS/NGF/RAC1/AKT1/PIK3R1/NTRK2/FGF17/MAP2K1/BCL2L1/BDNF/PTPN11/CSF1R/NF1/INS",29]
["hsa04935","Growth hormone synthesis, secretion and action","21/221","120/8223",5.40637966620295e-12,5.6766986495131e-11,1.81671867325848e-11,"CREBBP/IGF1/POU1F1/PRKACA/GSK3B/GNAS/MAPK1/EP300/MAPK3/MAPK8/CREB1/PIK3CA/MAP2K2/ATF4/KRAS/AKT1/PIK3R1/SST/MAP2K1/FOS/MTOR",21]
["hsa05226","Gastric cancer","23/221","149/8223",7.58385237976854e-12,7.66811740621041e-11,2.45403410339489e-11,"FGFR2/GSK3B/ABCB1/BAX/MAPK1/MAPK3/TGFB1/FGF8/PIK3CA/MAP2K2/KRAS/TP53/AKT1/PIK3R1/BRAF/FGF17/DVL3/SHH/CTNNB1/MAP2K1/BCL2/FZD2/MTOR",23]
["hsa04015","Rap1 signaling pathway","27/221","210/8223",8.85574768435319e-12,8.63435399224436e-11,2.76325961579442e-11,"IGF1/NGFR/FGFR2/FGFR3/FGFR1/GNAS/MAPK1/MAPK3/FGF8/VEGFA/PDGFRB/CNR1/PIK3CA/MAP2K2/KRAS/NGF/RAC1/AKT1/PIK3R1/DRD2/BRAF/FGF17/PRKCI/CTNNB1/MAP2K1/CSF1R/INS",27]
["hsa05152","Tuberculosis","25/221","180/8223",9.8653223744756e-12,9.28701037321324e-11,2.97212978976942e-11,"CREBBP/NOS2/TNFRSF1A/BAX/MAPK1/EP300/MAPK3/TGFB1/MAPK8/VDR/IFNG/IL1A/CREB1/IL1B/IL6/IL10/AKT1/IL18/FADD/BCL2/HLA-DQB1/HLA-DRB1/HLA-DQA1/IFNA1/TNF",25]
["hsa05418","Fluid shear stress and atherosclerosis","22/221","139/8223",1.33086646515859e-11,1.21108848329432e-10,3.87585672309344e-11,"TNFRSF1A/MAPK8/CCL2/IFNG/VEGFA/IL1A/DUSP1/PIK3CA/IL1B/GSTM1/RAC1/TP53/AKT1/PIK3R1/SQSTM1/NOS3/CTNNB1/FOS/BCL2/JUN/NQO1/TNF",22]
["hsa05225","Hepatocellular carcinoma","24/221","168/8223",1.42746950459583e-11,1.25709411211181e-10,4.02308892636516e-11,"ARID1B/GSK3B/BAX/SMARCB1/MAPK1/MAPK3/TGFB1/PIK3CA/MAP2K2/KRAS/GSTM1/TP53/AKT1/PIK3R1/CDKN2A/BRAF/DVL3/CTNNB1/MAP2K1/BCL2L1/PTEN/FZD2/NQO1/MTOR",24]
["hsa04211","Longevity regulating pathway","18/221","89/8223",1.50263850122107e-11,1.28193847135423e-10,4.10259853951805e-11,"IGF1/PRKACA/BAX/SIRT1/TSC2/PPARGC1A/SOD2/CREB1/PIK3CA/ATF4/KRAS/TP53/AKT1/PIK3R1/EHMT1/ADIPOQ/MTOR/INS",18]
["hsa05022","Pathways of neurodegeneration - multiple diseases","41/221","476/8223",1.64583237961704e-11,1.35968110421212e-10,4.35139894542532e-11,"NOS2/TNFRSF1B/TNFRSF1A/PTGS2/GSK3B/BAX/FUS/MAPK1/XBP1/MAPK3/MAPK8/IL1A/MFN2/IL1B/MAP2K2/ATF4/KRAS/RAC1/IL6/SOD1/SLC6A3/BRAF/SQSTM1/DVL3/CDK5/VCP/CTNNB1/FADD/MAP2K1/BCL2L1/BCL2/ATP2A2/BDNF/FZD2/PRKN/MAPT/LRRK2/MTOR/AGER/TNF/GPX1",41]
["hsa04668","TNF signaling pathway","20/221","114/8223",1.69337573418359e-11,1.35968110421212e-10,4.35139894542532e-11,"TNFRSF1B/TNFRSF1A/PTGS2/MAPK1/MAPK3/MAPK8/CCL2/CREB1/PIK3CA/IL1B/ATF4/LIF/IL6/AKT1/PIK3R1/FADD/MAP2K1/FOS/JUN/TNF",20]
["hsa04932","Non-alcoholic fatty liver disease","23/221","155/8223",1.75545260178457e-11,1.36925302939196e-10,4.38203205859004e-11,"TNFRSF1A/GSK3B/BAX/XBP1/TGFB1/MAPK8/IL1A/PIK3CA/IL1B/ATF4/CYP2E1/RAC1/IL6/AKT1/PIK3R1/IL6R/CXCL8/FOS/LEP/JUN/ADIPOQ/TNF/INS",23]
["hsa05164","Influenza A","24/221","171/8223",2.09954825995622e-11,1.5921574304668e-10,5.09539489989374e-11,"CREBBP/TNFRSF1A/BAX/MAPK1/EP300/MAPK3/CCL2/IFNG/IL1A/PIK3CA/IL1B/MAP2K2/IL6/AKT1/PIK3R1/IL18/FADD/MAP2K1/CXCL8/HLA-DQB1/HLA-DRB1/HLA-DQA1/IFNA1/TNF",24]
["hsa04926","Relaxin signaling pathway","21/221","129/8223",2.28836823469013e-11,1.68844467046056e-10,5.40354376896959e-11,"NOS2/PRKACA/GNAS/MAPK1/MAPK3/TGFB1/MAPK8/COL1A1/GNB3/VEGFA/CREB1/PIK3CA/MAP2K2/ATF4/KRAS/AKT1/PIK3R1/NOS3/MAP2K1/FOS/JUN",21]
["hsa04068","FoxO signaling pathway","21/221","131/8223",3.09976033683454e-11,2.22693308409429e-10,7.1268727966002e-11,"CREBBP/IGF1/SIRT1/MAPK1/EP300/MAPK3/TGFB1/MAPK8/SOD2/PIK3CA/MAP2K2/KRAS/IL6/IL10/AKT1/PLK2/PIK3R1/BRAF/MAP2K1/PTEN/INS",21]
["hsa04024","cAMP signaling pathway","27/221","225/8223",4.53043833862228e-11,3.17130683703559e-10,1.01491601108137e-10,"CREBBP/PRKACA/GNAS/MAPK1/EP300/OXT/MAPK3/MAPK8/POMC/CREB1/PIK3CA/NPY/MAP2K2/PPP1R1B/RAC1/AKT1/PIK3R1/DRD2/EDNRA/SST/BRAF/MAP2K1/FOS/ATP2A2/BDNF/JUN/PTCH1",27]
["hsa05135","Yersinia infection","21/221","137/8223",7.44695140376608e-11,5.08254433307035e-10,1.6265709645068e-10,"GSK3B/MAPK1/MAPK3/MAPK8/CCL2/IL2/PTK2B/PIK3CA/IL1B/MAP2K2/RAC1/IL6/IL10/AKT1/PIK3R1/IL18/MAP2K1/CXCL8/FOS/JUN/TNF",21]
["hsa04915","Estrogen signaling pathway","21/221","138/8223",8.5777023539008e-11,5.71149449418273e-10,1.82785441687745e-10,"PRKACA/GNAS/ESR1/FKBP5/MAPK1/MAPK3/OPRM1/POMC/CREB1/PIK3CA/MAP2K2/ATF4/KRAS/ESR2/AKT1/PIK3R1/NOS3/MAP2K1/FOS/BCL2/JUN",21]
["hsa05214","Glioma","16/221","75/8223",9.04711514810005e-11,5.88062484626503e-10,1.88198134659725e-10,"IGF1/BAX/MAPK1/MAPK3/PDGFRB/PIK3CA/MAP2K2/KRAS/TP53/AKT1/PIK3R1/CDKN2A/BRAF/MAP2K1/PTEN/MTOR",16]
["hsa05220","Chronic myeloid leukemia","16/221","76/8223",1.11898848825029e-10,7.10427575098439e-10,2.27358738126742e-10,"BAX/MAPK1/MAPK3/TGFB1/PIK3CA/MAP2K2/KRAS/TP53/AKT1/PIK3R1/CDKN2A/BRAF/MAP2K1/BCL2L1/PTPN11/HDAC2",16]
["hsa05213","Endometrial cancer","14/221","58/8223",2.42287828634906e-10,1.5032858458484e-09,4.8109784154778e-10,"GSK3B/BAX/MAPK1/MAPK3/PIK3CA/MAP2K2/KRAS/TP53/AKT1/PIK3R1/BRAF/CTNNB1/MAP2K1/PTEN",14]
["hsa04917","Prolactin signaling pathway","15/221","70/8223",3.34374215369237e-10,2.02853690657337e-09,6.49194383056063e-10,"GSK3B/ESR1/MAPK1/MAPK3/MAPK8/PIK3CA/MAP2K2/KRAS/ESR2/AKT1/PIK3R1/MAP2K1/FOS/PRL/INS",15]
["hsa04210","Apoptosis","20/221","136/8223",4.62950650467324e-10,2.74751146907781e-09,8.79288420796061e-10,"TNFRSF1A/BAX/MAPK1/MAPK3/MAPK8/PIK3CA/MAP2K2/ATF4/KRAS/NGF/TP53/AKT1/PIK3R1/FADD/MAP2K1/FOS/BCL2L1/BCL2/JUN/TNF",20]
["hsa04380","Osteoclast differentiation","19/221","128/8223",1.09419395151186e-09,6.35563720771784e-09,2.03399995465811e-09,"TNFRSF1A/MAPK1/MAPK3/TGFB1/MAPK8/IFNG/IL1A/CREB1/PIK3CA/IL1B/RAC1/AKT1/PIK3R1/SQSTM1/MAP2K1/FOS/JUN/CSF1R/TNF",19]
["hsa04550","Signaling pathways regulating pluripotency of stem cells","20/221","143/8223",1.15351506145742e-09,6.5606169120391e-09,2.09959978291593e-09,"PAX6/IGF1/FGFR2/FGFR3/FGFR1/GSK3B/REST/MAPK1/MAPK3/PIK3CA/MAP2K2/LIF/KRAS/AKT1/PIK3R1/DVL3/HESX1/CTNNB1/MAP2K1/FZD2",20]
["hsa05321","Inflammatory bowel disease","14/221","65/8223",1.23323662615145e-09,6.87088977427238e-09,2.19889666961484e-09,"TGFB1/IL2/IFNG/IL17A/IL1A/IL1B/IL6/IL10/IL18/JUN/HLA-DQB1/HLA-DRB1/HLA-DQA1/TNF",14]
["hsa05235","PD-L1 expression and PD-1 checkpoint pathway in cancer","16/221","89/8223",1.33790845881694e-09,7.30498018514047e-09,2.33781899119591e-09,"MAPK1/HIF1A/MAPK3/IFNG/PIK3CA/MAP2K2/KRAS/AKT1/PIK3R1/MAP2K1/FOS/ALK/PTEN/JUN/PTPN11/MTOR",16]
["hsa05140","Leishmaniasis","15/221","77/8223",1.38386764776451e-09,7.40776211450415e-09,2.37071237903931e-09,"NOS2/PTGS2/MAPK1/MAPK3/TGFB1/IFNG/IL1A/IL1B/IL10/FOS/JUN/HLA-DQB1/HLA-DRB1/HLA-DQA1/TNF",15]
["hsa04620","Toll-like receptor signaling pathway","17/221","104/8223",1.86646724604368e-09,9.61406713528158e-09,3.07679804213754e-09,"MAPK1/MAPK3/MAPK8/PIK3CA/IL1B/MAP2K2/RAC1/IL6/AKT1/PIK3R1/FADD/MAP2K1/CXCL8/FOS/JUN/IFNA1/TNF",17]
["hsa04660","T cell receptor signaling pathway","17/221","104/8223",1.86646724604368e-09,9.61406713528158e-09,3.07679804213754e-09,"DLG1/GSK3B/MAPK1/MAPK3/MAPK8/IL2/IFNG/PIK3CA/MAP2K2/KRAS/IL10/AKT1/PIK3R1/MAP2K1/FOS/JUN/TNF",17]
["hsa05010","Alzheimer disease","33/221","384/8223",2.18946441711573e-09,1.10689589976406e-08,3.54240831619114e-09,"NOS2/TNFRSF1A/PTGS2/GSK3B/MAPK1/XBP1/MAPK3/MAPK8/IL1A/PIK3CA/IL1B/MAP2K2/ATF4/APOE/KRAS/IL6/ADAM10/AKT1/PIK3R1/BRAF/DVL3/CDK5/CTNNB1/FADD/MAP2K1/ATP2A2/LPL/FZD2/MAPT/MTOR/AGER/TNF/INS",33]
["hsa04071","Sphingolipid signaling pathway","18/221","119/8223",2.24177747279769e-09,1.11273681831594e-08,3.56110105726714e-09,"TNFRSF1A/BAX/MAPK1/MAPK3/MAPK8/PIK3CA/MAP2K2/KRAS/RAC1/TP53/AKT1/PIK3R1/NOS3/MAP2K1/PRKCE/BCL2/PTEN/TNF",18]
["hsa05323","Rheumatoid arthritis","16/221","93/8223",2.62414155791496e-09,1.27926900948354e-08,4.09405543810041e-09,"TGFB1/CCL2/IFNG/IL17A/VEGFA/IL1A/IL1B/IL6/IL18/CXCL8/FOS/JUN/HLA-DQB1/HLA-DRB1/HLA-DQA1/TNF",16]
["hsa04659","Th17 cell differentiation","17/221","108/8223",3.40233403131812e-09,1.6295389307892e-08,5.21502723175261e-09,"MAPK1/HIF1A/MAPK3/TGFB1/MAPK8/IL2/IFNG/IL17A/IL1B/IL6/IL6R/FOS/JUN/HLA-DQB1/HLA-DRB1/HLA-DQA1/MTOR",17]
["hsa04910","Insulin signaling pathway","19/221","137/8223",3.53891734589458e-09,1.66573178522279e-08,5.33085553011343e-09,"PRKACA/GSK3B/MAPK1/MAPK3/TSC2/MAPK8/PRKAR1A/PPARGC1A/PIK3CA/MAP2K2/KRAS/AKT1/PIK3R1/BRAF/PRKCI/INPPL1/MAP2K1/MTOR/INS",19]
["hsa05034","Alcoholism","22/221","187/8223",4.65692590075461e-09,2.15481486594239e-08,6.89607225267855e-09,"HDAC9/HDAC4/PRKACA/GNAS/HDAC6/MAPK1/MAPK3/GNB3/CREB1/NPY/ATF4/PPP1R1B/KRAS/SLC6A3/NTRK2/DRD2/BRAF/MAP2K1/BDNF/MAOA/HDAC2/SLC29A3",22]
["hsa04020","Calcium signaling pathway","25/221","240/8223",5.00821972024707e-09,2.27873997271242e-08,7.29267082071065e-09,"CD38/NOS2/ERBB3/FGFR2/FGFR3/PRKACA/FGFR1/GNAS/P2RX7/HTR2A/FGF8/VEGFA/PDGFRB/PTK2B/GRPR/NGF/GNAL/NTRK2/EDNRA/FGF17/NOS3/RET/GDNF/ATP2A2/ERBB4",25]
["hsa05223","Non-small cell lung cancer","14/221","72/8223",5.11438430320965e-09,2.28889658160039e-08,7.32517510209493e-09,"BAX/MAPK1/MAPK3/PIK3CA/MAP2K2/KRAS/TP53/AKT1/PIK3R1/CDKN2A/BRAF/RET/MAP2K1/ALK",14]
["hsa05231","Choline metabolism in cancer","16/221","98/8223",5.79760934943863e-09,2.52646287609397e-08,8.0854605249971e-09,"MAPK1/HIF1A/MAPK3/TSC2/MAPK8/PDGFRB/PIK3CA/MAP2K2/KRAS/RAC1/AKT1/PIK3R1/MAP2K1/FOS/JUN/MTOR",16]
["hsa04012","ErbB signaling pathway","15/221","85/8223",5.83029894483225e-09,2.52646287609397e-08,8.0854605249971e-09,"ERBB3/GSK3B/MAPK1/MAPK3/MAPK8/PIK3CA/MAP2K2/KRAS/AKT1/PIK3R1/BRAF/MAP2K1/JUN/ERBB4/MTOR",15]
["hsa05219","Bladder cancer","11/221","41/8223",6.41053903440141e-09,2.73449555686185e-08,8.75122927393614e-09,"FGFR3/MAPK1/MAPK3/VEGFA/MAP2K2/KRAS/TP53/CDKN2A/BRAF/MAP2K1/CXCL8",11]
["hsa04916","Melanogenesis","16/221","101/8223",9.10707720557199e-09,3.82497242634024e-08,1.22410916285421e-08,"CREBBP/PRKACA/GSK3B/GNAS/MAPK1/EP300/MAPK3/POMC/CREB1/MAP2K2/KRAS/DVL3/CTNNB1/MAP2K1/FZD2/MC1R",16]
["hsa05170","Human immunodeficiency virus 1 infection","23/221","212/8223",9.87957329441549e-09,4.08655077178095e-08,1.30782230213156e-08,"TNFRSF1B/TNFRSF1A/BAX/MAPK1/MAPK3/MAPK8/GNB3/PTK2B/PIK3CA/MAP2K2/KRAS/RAC1/AKT1/PIK3R1/FADD/MAP2K1/FOS/BCL2L1/BCL2/JUN/IFNA1/MTOR/TNF",23]
["hsa05206","MicroRNAs in cancer","28/221","310/8223",1.38981635176664e-08,5.66298304525811e-08,1.8123292568206e-08,"CREBBP/BRCA1/ERBB3/HDAC4/FGFR3/PTGS2/NOTCH3/ABCB1/SIRT1/MAPK1/EP300/MAPK3/VEGFA/PDGFRB/STMN1/PIK3CA/MAP2K2/DNMT1/KRAS/TP53/PIK3R1/CDKN2A/MAP2K1/PRKCE/BCL2/PTEN/HDAC2/MTOR",28]
["hsa04630","JAK-STAT signaling pathway","20/221","166/8223",1.61193671298319e-08,6.47145180359428e-08,2.07106419779574e-08,"CREBBP/EP300/IL2/IFNG/PDGFRB/PIK3CA/LIF/GFAP/IL6/IL10/AKT1/PIK3R1/IL6R/BCL2L1/BCL2/PRL/LEP/PTPN11/IFNA1/MTOR",20]
["hsa05221","Acute myeloid leukemia","13/221","67/8223",1.88745292591635e-08,7.4677485329734e-08,2.38990988331132e-08,"MAPK1/MAPK3/PIK3CA/MAP2K2/PER2/KRAS/DUSP6/AKT1/PIK3R1/BRAF/MAP2K1/CSF1R/MTOR",13]
["hsa05203","Viral carcinogenesis","22/221","204/8223",2.35751806601661e-08,9.19432045746479e-08,2.94246615758465e-08,"CREBBP/HDAC9/HDAC4/PRKACA/DLG1/BAX/HDAC6/MAPK1/EP300/MAPK3/TBP/SRF/CREB1/PIK3CA/ATF4/KRAS/RAC1/TP53/PIK3R1/CDKN2A/JUN/HDAC2",22]
["hsa04657","IL-17 signaling pathway","15/221","94/8223",2.43165931363976e-08,9.30180007492696e-08,2.97686295052608e-08,"PTGS2/GSK3B/MAPK1/MAPK3/MAPK8/CCL2/IFNG/IL17A/IL1B/IL6/FADD/CXCL8/FOS/JUN/TNF",15]
["hsa04931","Insulin resistance","16/221","108/8223",2.45322199778294e-08,9.30180007492696e-08,2.97686295052608e-08,"TNFRSF1A/GSK3B/MAPK8/PPARGC1A/CREB1/PIK3CA/IL6/AKT1/PIK3R1/NOS3/PRKCE/PTEN/PTPN11/MTOR/TNF/INS",16]
["hsa05208","Chemical carcinogenesis - reactive oxygen species","23/221","223/8223",2.59533740114419e-08,9.7058508289365e-08,3.10617165529875e-08,"MAPK1/HIF1A/MAPK3/MAPK8/SOD2/VEGFA/PIK3CA/MAP2K2/CYP2E1/KRAS/GSTM1/RAC1/CYP1A2/SOD1/AKT1/PIK3R1/BRAF/MAP2K1/FOS/PTEN/JUN/PTPN11/NQO1",23]
["hsa04920","Adipocytokine signaling pathway","13/221","69/8223",2.74176310122811e-08,1.01148827923686e-07,3.23707450073873e-08,"TNFRSF1B/TNFRSF1A/ACSL4/MAPK8/PPARGC1A/POMC/NPY/AKT1/LEP/PTPN11/ADIPOQ/MTOR/TNF",13]
["hsa04934","Cushing syndrome","19/221","155/8223",2.81985777626003e-08,1.02642823055865e-07,3.28488695339765e-08,"PRKACA/GSK3B/GNAS/MAPK1/MAPK3/POMC/KMT2A/CREB1/MAP2K2/ATF4/PDE11A/MEN1/CDKN2A/BRAF/DVL3/KMT2D/CTNNB1/MAP2K1/FZD2",19]
["hsa05216","Thyroid cancer","10/221","37/8223",2.96137338129706e-08,1.06375649091329e-07,3.40434890093707e-08,"BAX/MAPK1/MAPK3/MAP2K2/KRAS/TP53/BRAF/RET/CTNNB1/MAP2K1",10]
["hsa04150","mTOR signaling pathway","19/221","156/8223",3.13536759194673e-08,1.09737865718136e-07,3.51195020420484e-08,"IGF1/TNFRSF1A/GSK3B/MAPK1/MAPK3/TSC2/PIK3CA/MAP2K2/KRAS/AKT1/PIK3R1/BRAF/DVL3/MAP2K1/PTEN/FZD2/MTOR/TNF/INS",19]
["hsa04218","Cellular senescence","19/221","156/8223",3.13536759194673e-08,1.09737865718136e-07,3.51195020420484e-08,"SIRT1/MAPK1/MAPK3/TSC2/TGFB1/IL1A/PIK3CA/MAP2K2/KRAS/IL6/TP53/AKT1/PIK3R1/CDKN2A/SQSTM1/MAP2K1/CXCL8/PTEN/MTOR",19]
["hsa04140","Autophagy - animal","18/221","141/8223",3.50744290834224e-08,1.21206571389548e-07,3.87898416245711e-08,"PRKACA/MAPK1/HIF1A/MAPK3/TSC2/MAPK8/PIK3CA/MAP2K2/KRAS/AKT1/PIK3R1/SQSTM1/MAP2K1/BCL2L1/BCL2/PTEN/MTOR/INS",18]
["hsa04370","VEGF signaling pathway","12/221","59/8223",3.87218948218338e-08,1.32138466079508e-07,4.22883851343712e-08,"PTGS2/MAPK1/MAPK3/VEGFA/PIK3CA/MAP2K2/KRAS/RAC1/AKT1/PIK3R1/NOS3/MAP2K1",12]
["hsa05030","Cocaine addiction","11/221","49/8223",4.89194246704057e-08,1.64876579444701e-07,5.27655912624259e-08,"PRKACA/GNAS/CREB1/ATF4/PPP1R1B/SLC6A3/DRD2/CDK5/BDNF/JUN/MAOA",11]
["hsa01524","Platinum drug resistance","13/221","73/8223",5.56458740880873e-08,1.85260044220095e-07,5.92889287459723e-08,"BRCA1/BAX/MAPK1/MAPK3/PIK3CA/GSTM1/TP53/AKT1/PIK3R1/CDKN2A/FADD/BCL2L1/BCL2",13]
["hsa04213","Longevity regulating pathway - multiple species","12/221","62/8223",6.95838774382028e-08,2.28872271573848e-07,7.32461867770556e-08,"IGF1/PRKACA/SIRT1/SOD2/PIK3CA/KRAS/SOD1/AKT1/PIK3R1/HDAC2/MTOR/INS",12]
["hsa04625","C-type lectin receptor signaling pathway","15/221","104/8223",9.83549440176799e-08,3.1965356805746e-07,1.02299001923151e-07,"PTGS2/MAPK1/MAPK3/MAPK8/IL2/PIK3CA/IL1B/KRAS/IL6/IL10/AKT1/PIK3R1/JUN/PTPN11/TNF",15]
["hsa05162","Measles","17/221","139/8223",1.61520981545443e-07,5.18767387787129e-07,1.66021566170548e-07,"GSK3B/BAX/MAPK8/IL2/IL1A/PIK3CA/IL1B/IL6/TP53/AKT1/PIK3R1/FADD/FOS/BCL2L1/BCL2/JUN/IFNA1",17]
["hsa05160","Hepatitis C","18/221","157/8223",1.86982897701827e-07,5.93561989216266e-07,1.89958145768074e-07,"TNFRSF1A/GSK3B/BAX/MAPK1/MAPK3/IFNG/PIK3CA/MAP2K2/KRAS/TP53/AKT1/PIK3R1/BRAF/CTNNB1/FADD/MAP2K1/IFNA1/TNF",18]
["hsa04936","Alcoholic liver disease","17/221","142/8223",2.21089544576861e-07,6.93763743327391e-07,2.22025797941675e-07,"TNFRSF1A/GSK3B/SIRT1/MAPK8/PPARGC1A/IL17A/IL1B/CYP2E1/IL6/AKT1/CTNNB1/FADD/CXCL8/ADIPOQ/IFNA1/TNF/ADH1C",17]
["hsa05145","Toxoplasmosis","15/221","112/8223",2.67448119739444e-07,8.29697007828047e-07,2.65528635626481e-07,"NOS2/TNFRSF1A/MAPK1/MAPK3/TGFB1/MAPK8/IFNG/IL10/AKT1/BCL2L1/BCL2/HLA-DQB1/HLA-DRB1/HLA-DQA1/TNF",15]
["hsa04930","Type II diabetes mellitus","10/221","46/8223",2.80344435492042e-07,8.59932931340758e-07,2.75205063818326e-07,"MAPK1/MAPK3/MAPK8/PIK3CA/PIK3R1/PRKCE/ADIPOQ/MTOR/TNF/INS",10]
["hsa04662","B cell receptor signaling pathway","13/221","84/8223",3.10785081985948e-07,9.42714748690708e-07,3.01697798886943e-07,"GSK3B/MAPK1/MAPK3/PIK3CA/MAP2K2/KRAS/RAC1/AKT1/PIK3R1/INPPL1/MAP2K1/FOS/JUN",13]
["hsa04072","Phospholipase D signaling pathway","17/221","148/8223",4.03883721639926e-07,1.21165116491978e-06,3.87765747786164e-07,"GNAS/MAPK1/MAPK3/TSC2/PDGFRB/PTK2B/PIK3CA/MAP2K2/KRAS/AKT1/PIK3R1/MAP2K1/CXCL8/PTPN11/F2/MTOR/INS",17]
["hsa04510","Focal adhesion","20/221","203/8223",4.67881340803365e-07,1.38838702216651e-06,4.44326673760633e-07,"IGF1/GSK3B/MAPK1/MAPK3/MAPK8/COL1A1/VEGFA/PDGFRB/PIK3CA/FLNB/RAC1/COL2A1/AKT1/PIK3R1/BRAF/CTNNB1/MAP2K1/BCL2/PTEN/JUN",20]
["hsa05146","Amoebiasis","14/221","102/8223",4.98244456581001e-07,1.46258856609262e-06,4.68073456663533e-07,"NOS2/PRKACA/GNAS/TGFB1/COL1A1/IFNG/PIK3CA/IL1B/IL6/IL10/GNAL/PIK3R1/CXCL8/TNF",14]
["hsa05133","Pertussis","12/221","76/8223",7.16978824514831e-07,2.08228956481435e-06,6.66396891766304e-07,"NOS2/MAPK1/MAPK3/MAPK8/IL1A/IL1B/IL6/IL10/CXCL8/FOS/JUN/TNF",12]
["hsa05332","Graft-versus-host disease","9/221","42/8223",1.28129885120192e-06,3.68204827766445e-06,1.17836902659013e-06,"IL2/IFNG/IL1A/IL1B/IL6/HLA-DQB1/HLA-DRB1/HLA-DQA1/TNF",9]
["hsa04940","Type I diabetes mellitus","9/221","43/8223",1.58300640759144e-06,4.50167447158814e-06,1.4406746911194e-06,"IL2/IFNG/IL1A/IL1B/HLA-DQB1/HLA-DRB1/HLA-DQA1/TNF/INS",9]
["hsa04664","Fc epsilon RI signaling pathway","11/221","68/8223",1.64262597650157e-06,4.62306073798896e-06,1.47952204069051e-06,"MAPK1/MAPK3/MAPK8/PIK3CA/MAP2K2/KRAS/RAC1/AKT1/PIK3R1/MAP2K1/TNF",11]
["hsa05031","Amphetamine addiction","11/221","69/8223",1.90854377426557e-06,5.31665765688267e-06,1.70149444966748e-06,"PRKACA/GNAS/SIRT1/CREB1/ATF4/PPP1R1B/SLC6A3/FOS/JUN/MAOA/HDAC2",11]
["hsa04726","Serotonergic synapse","14/221","115/8223",2.18933042459743e-06,6.03724450419291e-06,1.93210446827843e-06,"PRKACA/PTGS2/GNAS/MAPK1/CYP2D6/HTR2A/MAPK3/GNB3/DUSP1/KRAS/BRAF/CYP2C19/MAP2K1/MAOA",14]
["hsa04728","Dopaminergic synapse","15/221","132/8223",2.27924667783581e-06,6.22234343049176e-06,1.99134183431971e-06,"PRKACA/GSK3B/GNAS/COMT/MAPK8/GNB3/CREB1/ATF4/PPP1R1B/GNAL/AKT1/SLC6A3/DRD2/FOS/MAOA",15]
["hsa05131","Shigellosis","21/221","247/8223",2.71174862363022e-06,7.32977598268365e-06,2.34575441126949e-06,"TNFRSF1A/GSK3B/BAX/MAPK1/MAPK3/MAPK8/PIK3CA/IL1B/RAC1/TP53/AKT1/PIK3R1/IL18/SQSTM1/CXCL8/PRKCE/BCL2L1/BCL2/JUN/MTOR/TNF",21]
["hsa05132","Salmonella infection","21/221","249/8223",3.08489059243085e-06,8.25661893856492e-06,2.64237274687059e-06,"TNFRSF1A/BAX/MAPK1/MAPK3/MAPK8/PIK3CA/IL1B/MAP2K2/FLNB/RAC1/IL6/AKT1/IL18/CTNNB1/FADD/MAP2K1/CXCL8/FOS/BCL2/JUN/TNF",21]
["hsa04371","Apelin signaling pathway","15/221","139/8223",4.37280812864633e-06,1.15900642633053e-05,3.7091780753975e-06,"NOS2/HDAC4/PRKACA/NOTCH3/MAPK1/MAPK3/PPARGC1A/GNB3/MAP2K2/KRAS/AKT1/NOS3/MAP2K1/PRKCE/MTOR",15]
["hsa04960","Aldosterone-regulated sodium reabsorption","8/221","37/8223",4.72660610504715e-06,1.24073410257488e-05,3.97073184938172e-06,"IGF1/MAPK1/MAPK3/PIK3CA/KRAS/PIK3R1/NR3C2/INS",8]
["hsa04658","Th1 and Th2 cell differentiation","12/221","92/8223",5.74001410763805e-06,1.49240366798589e-05,4.77615208956349e-06,"NOTCH3/MAPK1/MAPK3/MAPK8/IL2/IFNG/FOS/JUN/HLA-DQB1/HLA-DRB1/HLA-DQA1/DLL1",12]
["hsa05144","Malaria","9/221","50/8223",5.97163936688408e-06,1.53797881807486e-05,4.92200662811697e-06,"TGFB1/CCL2/IFNG/IL1B/IL6/IL10/IL18/CXCL8/TNF",9]
["hsa04912","GnRH signaling pathway","12/221","93/8223",6.43618406103153e-06,1.64212920435664e-05,5.25531999080784e-06,"PRKACA/GNAS/MAPK1/MAPK3/MAPK8/PTK2B/MAP2K2/ATF4/KRAS/GNRH1/MAP2K1/JUN",12]
["hsa04929","GnRH secretion","10/221","64/8223",6.82172250729625e-06,1.724379856011e-05,5.51854744742289e-06,"MAPK1/MAPK3/PIK3CA/MAP2K2/KRAS/ESR2/AKT1/PIK3R1/GNRH1/MAP2K1",10]
["hsa04725","Cholinergic synapse","13/221","113/8223",9.57617673043679e-06,2.39843692422866e-05,7.67573798769922e-06,"PRKACA/MAPK1/MAPK3/GNB3/CREB1/PIK3CA/ATF4/KRAS/AKT1/PIK3R1/MAP2K1/FOS/BCL2",13]
["hsa04650","Natural killer cell mediated cytotoxicity","14/221","131/8223",1.02905676323833e-05,2.55393178512786e-05,8.17336950706044e-06,"MAPK1/MAPK3/IFNG/PTK2B/PIK3CA/MAP2K2/KRAS/RAC1/PIK3R1/BRAF/MAP2K1/PTPN11/IFNA1/TNF",14]
["hsa04720","Long-term potentiation","10/221","67/8223",1.04087577833317e-05,2.55999177914375e-05,8.19276335719803e-06,"CREBBP/PRKACA/MAPK1/EP300/MAPK3/MAP2K2/ATF4/KRAS/BRAF/MAP2K1",10]
["hsa04060","Cytokine-cytokine receptor interaction","22/221","295/8223",1.3106327480664e-05,3.19466732341184e-05,1.02239208730743e-05,"TNFRSF1B/NGFR/TNFRSF1A/TGFB1/CCL2/IL2/IFNG/IL17A/IL1A/IL1B/LIF/NGF/IL6/IL10/IL18/IL6R/CXCL8/PRL/LEP/CSF1R/IFNA1/TNF",22]
["hsa04914","Progesterone-mediated oocyte maturation","12/221","102/8223",1.68685474224863e-05,4.07532163392812e-05,1.30422863164077e-05,"IGF1/PRKACA/MAPK1/MAPK3/MAPK8/PIK3CA/KRAS/AKT1/PIK3R1/BRAF/MAP2K1/INS",12]
["hsa04215","Apoptosis - multiple species","7/221","32/8223",1.74817575821989e-05,4.18642089468447e-05,1.33978382208911e-05,"NGFR/TNFRSF1A/BAX/MAPK8/FADD/BCL2L1/BCL2",7]
["hsa04137","Mitophagy - animal","10/221","72/8223",2.00132965345408e-05,4.75098256863447e-05,1.5204609724182e-05,"HIF1A/MAPK8/MFN2/ATF4/KRAS/TP53/SQSTM1/BCL2L1/JUN/PRKN",10]
["hsa04928","Parathyroid hormone synthesis, secretion and action","12/221","106/8223",2.49984055593348e-05,5.88324544629172e-05,1.88282001944173e-05,"PRKACA/FGFR1/GNAS/MAPK1/MAPK3/VDR/CREB1/ATF4/BRAF/MAP2K1/FOS/BCL2",12]
["hsa05169","Epstein-Barr virus infection","17/221","202/8223",2.86899418879994e-05,6.69431977386652e-05,2.14238882294552e-05,"BAX/MAPK8/PIK3CA/RAC1/IL6/TP53/AKT1/PIK3R1/FADD/BCL2/JUN/HLA-DQB1/HLA-DRB1/HDAC2/HLA-DQA1/IFNA1/TNF",17]
["hsa04621","NOD-like receptor signaling pathway","16/221","186/8223",3.79334472158241e-05,8.77612804230506e-05,2.80863168502533e-05,"P2RX7/MAPK1/MAPK3/MAPK8/CCL2/MFN2/IL1B/IL6/IL18/FADD/CXCL8/BCL2L1/BCL2/JUN/IFNA1/TNF",16]
["hsa04810","Regulation of actin cytoskeleton","18/221","229/8223",4.15919570407898e-05,9.47603695158251e-05,3.03262412562695e-05,"FGFR2/FGFR3/FGFR1/MAPK1/MAPK3/FGF8/PDGFRB/PIK3CA/MAP2K2/KRAS/RAC1/AKT1/PIK3R1/BRAF/FGF17/MAP2K1/F2/INS",18]
["hsa05217","Basal cell carcinoma","9/221","63/8223",4.16529096772858e-05,9.47603695158251e-05,3.03262412562695e-05,"GLI2/GSK3B/BAX/TP53/DVL3/SHH/CTNNB1/FZD2/PTCH1",9]
["hsa05143","African trypanosomiasis","7/221","37/8223",4.76939196425431e-05,0.000107606942664581,3.44375409337197e-05,"IFNG/IL1B/IDO1/IL6/IL10/IL18/TNF",7]
["hsa05171","Coronavirus disease - COVID-19","18/221","232/8223",4.938925129114e-05,0.000110518570512141,3.53693516580208e-05,"TNFRSF1A/MAPK1/MAPK3/MAPK8/CCL2/IL2/PIK3CA/IL1B/IL6/PIK3R1/ACE/IL6R/CXCL8/FOS/JUN/F2/IFNA1/TNF",18]
["hsa05330","Allograft rejection","7/221","38/8223",5.7142576927784e-05,0.000126828646351911,4.05890790330002e-05,"IL2/IFNG/IL10/HLA-DQB1/HLA-DRB1/HLA-DQA1/TNF",7]
["hsa05202","Transcriptional misregulation in cancer","16/221","193/8223",5.94401231733748e-05,0.000130864142147833,4.18805621679975e-05,"IGF1/NGFR/BAX/FUS/KMT2A/PER2/MEN1/IL6/DUSP6/TP53/KDM6A/CXCL8/BCL2L1/CSF1R/PAX5/HDAC2",16]
["hsa04061","Viral protein interaction with cytokine and cytokine receptor","11/221","100/8223",7.13543870666125e-05,0.000155837981353482,4.9872961065506e-05,"TNFRSF1B/TNFRSF1A/CCL2/IL2/IL6/IL10/IL18/IL6R/CXCL8/CSF1R/TNF",11]
["hsa05320","Autoimmune thyroid disease","8/221","53/8223",7.49367389184016e-05,0.000162362934323203,5.19611472867781e-05,"TG/IL2/TPO/IL10/HLA-DQB1/HLA-DRB1/HLA-DQA1/IFNA1",8]
["hsa05130","Pathogenic Escherichia coli infection","16/221","197/8223",7.60406191690858e-05,0.000163457393961893,5.23114081312401e-05,"TNFRSF1A/BAX/MAPK1/MAPK3/MAPK8/IL1B/RAC1/IL6/IL18/FADD/CXCL8/FOS/JUN/PTPN11/F2/TNF",16]
["hsa04152","AMPK signaling pathway","12/221","121/8223",9.32592216074773e-05,0.000198904433584698,6.3655554222209e-05,"IGF1/SIRT1/TSC2/PPARGC1A/CREB1/PIK3CA/AKT1/PIK3R1/LEP/ADIPOQ/MTOR/INS",12]
["hsa04540","Gap junction","10/221","88/8223",0.000115783381866194,0.000245029947670318,7.84171415332036e-05,"PRKACA/GNAS/MAPK1/HTR2A/MAPK3/PDGFRB/MAP2K2/KRAS/DRD2/MAP2K1",10]
["hsa00982","Drug metabolism - cytochrome P450","9/221","72/8223",0.000121474214649423,0.000255095850763789,8.16385410194504e-05,"CYP2D6/CYP2E1/GSTM1/CYP1A2/CYP3A4/CYP2C19/MAOA/CYP2B6/ADH1C",9]
["hsa04080","Neuroactive ligand-receptor interaction","23/221","367/8223",0.000127728006503006,0.000266181265460464,8.51862156669307e-05,"TAC1/GABRA3/P2RX7/TSPO/OXT/HTR2A/OPRM1/NR3C1/POMC/CNR1/NPY/GRPR/NTS/GNRH1/DRD2/EDNRA/SST/PRL/LEP/F2/PENK/CCK/MC1R",23]
["hsa04923","Regulation of lipolysis in adipocytes","8/221","58/8223",0.000144400465782642,0.000298646417868646,9.5576065868894e-05,"PRKACA/PTGS2/GNAS/PIK3CA/NPY/AKT1/PIK3R1/INS",8]
["hsa04918","Thyroid hormone synthesis","9/221","75/8223",0.000167172727141535,0.000343144018869467,0.000109816670777582,"TG/PRKACA/GNAS/TPO/CREB1/TTR/ATF4/ALB/GPX1",9]
["hsa05222","Small cell lung cancer","10/221","92/8223",0.000168437704502696,0.000343160397979373,0.000109821912597987,"NOS2/PTGS2/BAX/PIK3CA/TP53/AKT1/PIK3R1/BCL2L1/BCL2/PTEN",10]
["hsa04730","Long-term depression","8/221","60/8223",0.000184065450507871,0.000372221244360362,0.000119122279860845,"IGF1/GNAS/MAPK1/MAPK3/MAP2K2/KRAS/BRAF/MAP2K1",8]
["hsa04062","Chemokine signaling pathway","15/221","192/8223",0.000196714426260919,0.000394875282126697,0.000126372270740373,"PRKACA/GSK3B/MAPK1/MAPK3/CCL2/GNB3/PTK2B/PIK3CA/KRAS/RAC1/AKT1/PIK3R1/BRAF/MAP2K1/CXCL8",15]
["hsa04921","Oxytocin signaling pathway","13/221","154/8223",0.000246796707732988,0.000491791979643107,0.000157388603471671,"CD38/PRKACA/PTGS2/GNAS/MAPK1/OXT/MAPK3/MAP2K2/KRAS/NOS3/MAP2K1/FOS/JUN",13]
["hsa05012","Parkinson disease","18/221","266/8223",0.000281198022787973,0.000556283045080555,0.000178027733725414,"PRKACA/BAX/GNAS/XBP1/MAPK8/MFN2/DUSP1/ATF4/GNAL/TP53/SOD1/SLC6A3/DRD2/BCL2L1/PRKN/MAPT/LRRK2/MAOA",18]
["hsa04750","Inflammatory mediator regulation of TRP channels","10/221","98/8223",0.000284339805222748,0.000558451559897916,0.000178721725357729,"IGF1/PRKACA/GNAS/HTR2A/MAPK8/PIK3CA/IL1B/NGF/PIK3R1/PRKCE",10]
["hsa04672","Intestinal immune network for IgA production","7/221","49/8223",0.000302640608092247,0.000590149185779881,0.000188865943395913,"TGFB1/IL2/IL6/IL10/HLA-DQB1/HLA-DRB1/HLA-DQA1",7]
["hsa04640","Hematopoietic cell lineage","10/221","99/8223",0.000308982701042291,0.000598243102018053,0.000191456246259874,"CD38/IL1A/IL1B/IL6/IL6R/HLA-DQB1/CSF1R/HLA-DRB1/HLA-DQA1/TNF",10]
["hsa05415","Diabetic cardiomyopathy","15/221","203/8223",0.000360409916627764,0.000692900755206899,0.000221749615123087,"GSK3B/TGFB1/MAPK8/COL1A1/PIK3CA/RAC1/AKT1/PIK3R1/ACE/NOS3/PTEN/ATP2A2/MTOR/AGER/INS",15]
["hsa04611","Platelet activation","11/221","124/8223",0.000484710012527567,0.000925355478461719,0.0002961422969436,"PRKACA/GNAS/MAPK1/MAPK3/COL1A1/PIK3CA/AKT1/PIK3R1/PRKCI/NOS3/F2",11]
["hsa04022","cGMP-PKG signaling pathway","13/221","167/8223",0.000542582888856133,0.00102864672678975,0.000329198682566221,"MAPK1/MAPK3/SRF/CREB1/MAP2K2/ATF4/AKT1/EDNRA/NOS3/MAP2K1/PRKCE/ATP2A2/INS",13]
["hsa04922","Glucagon signaling pathway","10/221","107/8223",0.000578137298067827,0.00108730880000965,0.000347972355507233,"CREBBP/PRKACA/GNAS/SIRT1/EP300/PPARGC1A/CREB1/ATF4/LDHA/AKT1",10]
["hsa04613","Neutrophil extracellular trap formation","14/221","190/8223",0.000581491153118714,0.00108730880000965,0.000347972355507233,"HDAC9/HDAC4/HDAC6/MAPK1/MAPK3/PIK3CA/MAP2K2/RAC1/AKT1/PIK3R1/MAP2K1/HDAC2/MTOR/AGER",14]
["hsa04310","Wnt signaling pathway","13/221","170/8223",0.000642648601149172,0.00119349025927703,0.000381953697782895,"CREBBP/PRKACA/GSK3B/EP300/SFRP1/MAPK8/RAC1/TP53/DVL3/CTNNB1/JUN/FZD2/TLE1",13]
["hsa04115","p53 signaling pathway","8/221","73/8223",0.000717015025866667,0.00132260204095676,0.000423273450547179,"IGF1/BAX/TSC2/TP53/CDKN2A/BCL2L1/BCL2/PTEN",8]
["hsa04330","Notch signaling pathway","7/221","59/8223",0.000957588518671268,0.00175450782280038,0.000561496623452598,"CREBBP/NOTCH3/EP300/DVL3/HDAC2/TLE1/DLL1",7]
["hsa04350","TGF-beta signaling pathway","9/221","96/8223",0.00106034147957954,0.00192308097542272,0.000615445232157648,"CREBBP/MAPK1/EP300/MAPK3/TGFB1/IFNG/FBN1/TGIF1/TNF",9]
["hsa05020","Prion disease","17/221","273/8223",0.00106368215124114,0.00192308097542272,0.000615445232157648,"PRKACA/GSK3B/BAX/MAPK1/MAPK3/MAPK8/IL1A/CREB1/PIK3CA/IL1B/ATF4/RAC1/IL6/SOD1/PIK3R1/NCAM1/TNF",17]
["hsa04666","Fc gamma R-mediated phagocytosis","9/221","97/8223",0.00114205515175273,0.00205119116071378,0.000656444443181969,"MAPK1/MAPK3/PIK3CA/RAC1/AKT1/PIK3R1/INPPL1/MAP2K1/PRKCE",9]
["hsa04217","Necroptosis","12/221","159/8223",0.00115897912471349,0.0020679823597829,0.000661818144831233,"TNFRSF1A/BAX/MAPK8/IFNG/IL1A/IL1B/GLUL/SQSTM1/FADD/BCL2/IFNA1/TNF",12]
["hsa04360","Axon guidance","13/221","182/8223",0.00121291366256328,0.00215016512908945,0.00068811916604752,"GSK3B/MAPK1/MAPK3/PIK3CA/KRAS/RAC1/PIK3R1/SHH/CDK5/PTPN11/PTCH1/DCC/L1CAM",13]
["hsa05310","Asthma","5/221","31/8223",0.00128670304104465,0.00226625761422702,0.000725272342320581,"IL10/HLA-DQB1/HLA-DRB1/HLA-DQA1/TNF",5]
["hsa05014","Amyotrophic lateral sclerosis","20/221","364/8223",0.00183421075082049,0.00320986881393585,0.00102725703318556,"NOS2/TNFRSF1B/TNFRSF1A/BAX/FUS/HDAC6/XBP1/ATF4/RAC1/TP53/SOD1/SQSTM1/VCP/BCL2L1/BCL2/ERBB4/PRKN/MTOR/TNF/GPX1",20]
["hsa04520","Adherens junction","7/221","71/8223",0.00284508034275653,0.00494717792084417,0.00158324953703515,"CREBBP/FGFR1/MAPK1/EP300/MAPK3/RAC1/CTNNB1",7]
["hsa04340","Hedgehog signaling pathway","6/221","56/8223",0.00372527918871377,0.00643671657290417,0.00205994785251994,"PRKACA/GLI2/GSK3B/SHH/BCL2/PTCH1",6]
["hsa05134","Legionellosis","6/221","57/8223",0.00407218554842086,0.00699186575294902,0.00223761271445833,"IL1B/IL6/IL18/VCP/CXCL8/TNF",6]
["hsa04713","Circadian entrainment","8/221","97/8223",0.00445102567204198,0.00759456255292162,0.00243049428144397,"PRKACA/GNAS/MAPK1/MAPK3/GNB3/CREB1/PER2/FOS",8]
["hsa00980","Metabolism of xenobiotics by cytochrome P450","7/221","78/8223",0.00482662802757773,0.0081842823076318,0.0026192227936512,"CYP2D6/CYP2E1/GSTM1/CYP1A2/CYP3A4/CYP2B6/ADH1C",7]
["hsa00591","Linoleic acid metabolism","4/221","30/8223",0.00803952625641139,0.0134649734233148,0.00430920684069839,"CYP2E1/CYP1A2/CYP3A4/CYP2C19",4]
["hsa01523","Antifolate resistance","4/221","30/8223",0.00803952625641139,0.0134649734233148,0.00430920684069839,"IL1B/IL6/MTHFR/TNF",4]
["hsa04270","Vascular smooth muscle contraction","9/221","134/8223",0.00994533244046204,0.0165553399771106,0.005298219464431,"PRKACA/GNAS/MAPK1/MAPK3/MAP2K2/EDNRA/BRAF/MAP2K1/PRKCE",9]
["hsa05204","Chemical carcinogenesis - DNA adducts","6/221","69/8223",0.0103172289840439,0.0170703243190544,0.00546303033923855,"PTGS2/CYP2E1/GSTM1/CYP1A2/CYP3A4/CYP2C19",6]
["hsa05410","Hypertrophic cardiomyopathy","7/221","90/8223",0.0104250060120531,0.0171447388029547,0.00548684526950162,"IGF1/TGFB1/IL6/ACE/ATP2A2/DMD/TNF",7]
["hsa05120","Epithelial cell signaling in Helicobacter pylori infection","6/221","70/8223",0.0110385478548588,0.0180450512836914,0.0057749730346882,"MAPK8/RAC1/ADAM10/CXCL8/JUN/PTPN11",6]
["hsa04913","Ovarian steroidogenesis","5/221","51/8223",0.0115317823374891,0.0186282637759439,0.00596161902218371,"IGF1/PRKACA/PTGS2/GNAS/INS",5]
["hsa04979","Cholesterol metabolism","5/221","51/8223",0.0115317823374891,0.0186282637759439,0.00596161902218371,"APOB/TSPO/APOE/CYP27A1/LPL",5]
["hsa05414","Dilated cardiomyopathy","7/221","96/8223",0.0145421264436188,0.0233529442300466,0.00747366250662761,"IGF1/PRKACA/GNAS/TGFB1/ATP2A2/DMD/TNF",7]
["hsa00350","Tyrosine metabolism","4/221","36/8223",0.0152513221475094,0.0243486020249712,0.00779230371340895,"COMT/TPO/MAOA/ADH1C",4]
["hsa05016","Huntington disease","15/221","306/8223",0.0178157606930122,0.0282773410999554,0.00904962140465123,"CREBBP/REST/BAX/EP300/MAPK8/PPARGC1A/SOD2/TBP/CREB1/TP53/SOD1/BDNF/HDAC2/MTOR/GPX1",15]
["hsa04612","Antigen processing and presentation","6/221","78/8223",0.0181375918899904,0.0286217490518345,0.00915984257297962,"IFNG/CREB1/HLA-DQB1/HLA-DRB1/HLA-DQA1/TNF",6]
["hsa00220","Arginine biosynthesis","3/221","22/8223",0.0202308846615887,0.0317415604173201,0.0101582784447178,"NOS2/GLUL/NOS3",3]
["hsa04110","Cell cycle","8/221","127/8223",0.0209068038582934,0.0326146140189378,0.0104376825277495,"CREBBP/GSK3B/EP300/TGFB1/SMC3/TP53/CDKN2A/HDAC2",8]
["hsa04064","NF-kappa B signaling pathway","7/221","104/8223",0.0216834811026143,0.0336340360284869,0.0107639290162499,"TNFRSF1A/PTGS2/IL1B/CXCL8/BCL2L1/BCL2/TNF",7]
["hsa05416","Viral myocarditis","5/221","60/8223",0.0221035219249886,0.0340918727995587,0.0109104509055846,"RAC1/HLA-DQB1/HLA-DRB1/HLA-DQA1/DMD",5]
["hsa04714","Thermogenesis","12/221","232/8223",0.0224430977606823,0.0344211555543048,0.0110158315442734,"ARID1B/ACSL4/PRKACA/FGFR1/GNAS/SMARCB1/TSC2/PPARGC1A/CREB1/CNR1/KRAS/MTOR",12]
["hsa04261","Adrenergic signaling in cardiomyocytes","9/221","154/8223",0.0228467218264526,0.0348444416682769,0.0111512961575746,"PRKACA/GNAS/MAPK1/MAPK3/CREB1/ATF4/AKT1/BCL2/ATP2A2",9]
["hsa04114","Oocyte meiosis","8/221","131/8223",0.0246563200144249,0.0373954186885445,0.0119676874923817,"IGF1/PRKACA/MAPK1/MAPK3/SMC3/MAP2K1/AR/INS",8]
["hsa00140","Steroid hormone biosynthesis","5/221","62/8223",0.0250935809330488,0.0378483292526095,0.0121126328435187,"COMT/CYP2E1/CYP1A2/SRD5A1/CYP3A4",5]
["hsa04911","Insulin secretion","6/221","86/8223",0.0278699554855929,0.0418049332283893,0.013378868162546,"PRKACA/GNAS/CREB1/ATF4/CCK/INS",6]
["hsa04927","Cortisol synthesis and secretion","5/221","65/8223",0.0300457212648768,0.0448223054935048,0.0143445203622938,"PRKACA/GNAS/POMC/CREB1/ATF4",5]
["hsa05032","Morphine addiction","6/221","91/8223",0.0354342791933639,0.0525736859771105,0.0168252012188169,"GABRA3/PRKACA/GNAS/GNB3/OPRM1/PDE11A",6]
["hsa04924","Renin secretion","5/221","69/8223",0.0375470163573072,0.0554072187326749,0.0177320191047311,"PRKACA/GNAS/CREB1/EDNRA/ACE",5]
["hsa05017","Spinocerebellar ataxia","8/221","143/8223",0.0386806791882971,0.0567732549376619,0.0181691928275533,"XBP1/MAPK8/TBP/PIK3CA/AKT1/PIK3R1/ATP2A2/MTOR",8]
["hsa04622","RIG-I-like receptor signaling pathway","5/221","71/8223",0.0416915279088926,0.0608651717600411,0.0194787324313993,"MAPK8/FADD/CXCL8/IFNA1/TNF",5]
["hsa04723","Retrograde endocannabinoid signaling","8/221","148/8223",0.0458444901513424,0.0665720521878536,0.0213051102047112,"GABRA3/PRKACA/PTGS2/MAPK1/MAPK3/MAPK8/GNB3/CNR1",8]
["hsa00270","Cysteine and methionine metabolism","4/221","51/8223",0.0475035906556412,0.0686162976137039,0.0219593317984863,"GCLC/MTR/DNMT1/LDHA",4]
["hsa04925","Aldosterone synthesis and secretion","6/221","98/8223",0.0480690800584153,0.0690676781891968,0.0221037875060857,"PRKACA/GNAS/POMC/CREB1/ATF4/PRKCE",6]