# gene_ID : unique identifier of gene model in format ContigName.ID # index_sort_by_gene_ID : Gene ID padded with zeros to allow sensible sorting # index_sort_by_expression : sort so genes are grouped by expression in gonozooids as shown in tables 1 and 2 # is_in_table1_or_table_2 : gene appears in Table 1 or Table 2 # SATC_flag : flag assigned to contig by SATC # linkage_group : linkage group where gene is located in linkage map # is_in_nrr : yes if gene is in the non-recombining region of LG4 in the linkage map # deficit in female coverage : yes if gene has little to no coverage in female samples # gast_exp_1 : FPKM in gastrozooid library 1 from Sanders et al 2014 BMC Genomics # gast_exp_2 : FPKM in gastrozooid library 2 from Sanders et al 2014 BMC Genomics # gast_exp_3 : FPKM in gastrozooid library 3 from Sanders et al 2014 BMC Genomics # gast_exp_4 : FPKM in gastrozooid library 4 from Sanders et al 2014 BMC Genomics # fem_gono_exp_1 : FPKM in female gonozooid library 1 from Sanders et al 2014 BMC Genomics # fem_gono_exp_2 : FPKM in female gonozooid library 2 from Sanders et al 2014 BMC Genomics # male_gono_exp_1 : FPKM in male gonozooid library 1 from Sanders et al 2014 BMC Genomics # male_gono_exp_2 : FPKM in male gonozooid library 2 from Sanders et al 2014 BMC Genomics # mean_gastro_exp : mean FPKM of gastrozooid libraries 1-4 # mean_female_gono_exp : mean FPKM of male gonozooid libraries 1-2 # mean_male_gono_exp : mean FPKM of female gonozooid libraries 1-2 "# exp_in_gastro_1fkpm : 1 if expressed in gastrozooids at 1 fkpm threshold, 0 if not" "# exp_in_fem_gono_1fkpm : 1 if expressed in female gonozooids at 1 fkpm threshold, 0 if not" "# exp_in_male_gono_1fkpm : 1 if expressed in male gonozooids at 1 fkpm threshold, 0 if not" "# unexpressed_1fkpm : 1 if unexpressed 1 fkpm threshold, 0 if not" "# gastro_only_exp_1fkpm : 1 if expressed only in gastrozooids at 1 fkpm threshold, 0 if not" "# gastro_and_gono_exp_1fkpm : 1 if expressed in gastrozooids and gonozooids 1 fkpm threshold, 0 if not" "# gono_specific_1fkpm : 1 if gonozooids specific 1 fkpm threshold, 0 if not" "# fem_gono_specific_1fkpm : 1 if only expressed in male gonozooids at 1 fkpm threshold, 0 if not" "# male_gono_specific_1fkpm : 1 if only expressed in female gonozooids at 1 fkpm threshold, 0 if not" "# exp_in_gastro_5fkpm : 1 if expressed in gastrozooids at 5 fkpm threshold, 0 if not" "# exp_in_fem_gono_5fkpm : 1 if expressed in female gonozooids at 5 fkpm threshold, 0 if not" "# exp_in_male_gono_5fkpm : 1 if expressed in male gonozooids at 5 fkpm threshold, 0 if not" "# unexpressed_5fkpm : 1 if unexpressed 5 fkpm threshold, 0 if not" "# gastro_only_exp_5fkpm : 1 if expressed only in gastrozooids at 5 fkpm threshold, 0 if not" "# gastro_and_gono_exp_5fkpm : 1 if expressed in gastrozooids and gonozooids 5 fkpm threshold, 0 if not" "# gono_specific_5fkpm : 1 if gonozooids specific 5 fkpm threshold, 0 if not" "# fem_gono_specific_5fkpm : 1 if only expressed in male gonozooids at 5 fkpm threshold, 0 if not" "# male_gono_specific_5fkpm : 1 if only expressed in female gonozooids at 5 fkpm threshold, 0 if not" # blastp_vs_nr_desc : description of top blastp hit vs non-redundant protein database # blastp_vs_nr_eval : e-value of top blastp hit vs non-redundant protein database # blastp_vs_nr_hit_accession : accession of top blastp hit vs non-redundant protein database # blastp_vs_landmark_desc : description of top blastp hit vs landmark database # blastp_vs_landmark_taxon : taxon of top blastp hit vs landmark database # blastp_vs_landmark_bitscore : bitscore of top blastp hit vs landmark database # blastp_vs_landmark_query_cov : coverage of candidate gene by top blastp hit in landmark database # blastp_vs_landmark_eval : evalue of top blastp hit vs landmark databse # blastp_vs_landmark_pid : percent identity of top blastp hit vs landmark database # blastp_vs_landmark_accession : accession of top blastp hit vs landmark database # pannzer_description : self-explanatory # pannzer_gene : self-explanatory # pannzer_GO_molecular_function : self-explanatory # pannzer_GO_biological_process : self-explanatory # pannzer_GO_cellular_component : self-explanatory "# HMMER_pfam_hits : ÒPFAMID DescriptionÓ, multiple domains separated by semi-colon (;)" "# author_comment : homology, notable domains, or likely function as assessed by authors" gene_ID index_sort_by_gene_ID index_sort_by_expression is_in_table1_or_table_2 SATC_flag linkage_group is_in_nrr deficit in female coverage gast_exp_1 gast_exp_2 gast_exp_3 gast_exp_4 fem_gono_exp_1 fem_gono_exp_2 male_gono_exp_1 male_gono_exp_2 mean_gastro_exp mean_female_gono_exp mean_male_gono_exp exp_in_gastro_1fkpm exp_in_fem_gono_1fkpm exp_in_male_gono_1fkpm unexpressed_1fkpm gastro_only_exp_1fkpm gastro_and_gono_exp_1fkpm gono_specific_1fkpm fem_gono_specific_1fkpm male_gono_specific_1fkpm exp_in_gastro_5fkpm exp_in_fem_gono_5fkpm exp_in_male_gono_5fkpm unexpressed_5fkpm gastro_only_exp_5fkpm gastro_and_gono_exp_5fkpm gono_specific_5fkpm fem_gono_specific_5fkpm male_gono_specific_5fkpm blastp_vs_nr_desc blastp_vs_nr_eval blastp_vs_nr_hit_accession blastp_vs_landmark_desc blastp_vs_landmark_taxon blastp_vs_landmark_bitscore blastp_vs_landmark_query_cov blastp_vs_landmark_eval blastp_vs_landmark_pid blastp_vs_landmark_accession pannzer_description pannzer_gene pannzer_GO_molecular_function pannzer_GO_biological_process pannzer_GO_cellular_component HMMER_pfam_hits author_comment HyS1036.2 HyS1036.002 1 (cutoff = 1) female specific sex-linked-abnormal 4 - - 0 0.293036 0.312197 0 21.956 23.2804 0.748162 0.197695 0.15130825 22.6182 0.4729285 0 1 0 0 0 0 1 1 0 0 1 0 0 0 0 1 1 0 no hits - - Helix-loop-helix protein 10 Caenorhabditis elegans 45.8 23 1.26E-04 39.062 NP_505401 NA NA NA NA NA PF00010.28: HLH; PF00962.24: A_deaminase; PF17428.4: DUF5412; helix-loop-helix domain containing protein HyS2624.2 HyS2624.002 2 (cutoff = 1) female specific sex-linked-abnormal - - - 0 0 0 0 11.4627 13.4809 0 0 0 12.4718 0 0 1 0 0 0 0 1 1 0 0 1 0 0 0 0 1 1 0 no hits - - no hits - - - - - - NA NA NA NA NA - unknown function HyS0007.332 HyS0007.332 3 (cutoff = 1) female specific - 4 yes - 0 0 0 0 8.90374 10.4146 0 0 0 9.65917 0 0 1 0 0 0 0 1 1 0 0 1 0 0 0 0 1 1 0 no hits - - no hits - - - - - - NA NA NA NA NA PF08726.12: EFhand_Ca_insen; unknown function HyS0116.3 HyS0116.003 4 (cutoff = 1) female specific sex-linked-abnormal 4 yes - 0 0 0 0 6.66963 4.87682 0 0 0 5.773225 0 0 1 0 0 0 0 1 1 0 0 1 0 0 0 0 1 1 0 uncharacterized protein LOC114515612 [Dendronephthya gigantea] 7.80E-22 XP_028390702.1 uncharacterized protein LOC101882990 Danio rerio 79.3 73 5.64E-16 31.515 XP_009296423 NA NA NA NA NA - unknown function HyS0070.121 HyS0070.121 5 (cutoff = 1) female specific sex-linked-abnormal - - - 0 0 0 0 2.716 1.65492 0.33577 0.266112 0 2.18546 0.300941 0 1 0 0 0 0 1 1 0 0 0 0 1 0 0 0 0 0 reverse transcriptase [Lasius niger] 5.90E-22 KMQ88340.1 no hits - - - - - - NA NA NA NA NA PF13966.8: zf-RVT; PF17586.4: DUF5485; reverse transcriptase-like protein HyS0120.5 HyS0120.005 6 (cutoff = 1) female specific sex-linked-abnormal 4 yes - 0 0 0 0 1.68676 1.59803 0 0 0 1.642395 0 0 1 0 0 0 0 1 1 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - unknown function HyS0328.2 HyS0328.002 7 (cutoff = 1) female specific sex-linked-abnormal - - - 0 0 0 0 1.42852 0.676578 0 0 0 1.052549 0 0 1 0 0 0 0 1 1 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF15928.7: DUF4746; unknown function HyS0070.32 HyS0070.032 8 (cutoff = 1) female specific sex-linked-abnormal - - - 0.809271 0.822643 0.146006 0.276083 1.34817 0.703235 0 0.275831 0.51350075 1.0257025 0.1379155 0 1 0 0 0 0 1 1 0 0 0 0 1 0 0 0 0 0 PREDICTED: headcase protein homolog isoform X1 [Hydra vulgaris] 8.30E-55 XP_012555232.1 headcase protein homolog isoform X1 Mus musculus 140 65 2.51E-36 34.615 XP_006512846 "Hdc homolog, cell cycle regulator" HECA unfolded protein binding protein folding NA PF16002.7: Headcase; headcase protein HyS0007.350 HyS0007.350 9 (cutoff = 1) female specific - 4 yes - 0 1.44014 0 0 0 2.70631 1.24706 0.493796 0.360035 1.353155 0.870428 0 1 0 0 0 0 1 1 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - unknown function HyS0070.46 HyS0070.046 10 (cutoff = 1) male specific sex-linked-abnormal - - - 0.444283 0.602029 0.320565 0 0 0.210577 428.006 288.808 0.34171925 0.1052885 358.407 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 1 0 1 no hits - - no hits - - - - - - NA NA NA NA NA PF05010.16: TACC_C; unknown function HyS0057.51 HyS0057.051 11 (cutoff = 1) male specific - 4 yes - 0.31773 0.0539052 0.172171 2.82734 0 0.0502101 363.673 265.998 0.84278655 0.02510505 314.8355 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 1 0 1 neural Wiskott-Aldrich syndrome protein-like [Dendronephthya gigantea] 7.00E-08 XP_028413484.1 wiskott-Aldrich syndrome protein isoform X1 Homo sapiens 61.2 10 4.67E-08 28.682 XP_011542279 NA NA NA NA NA PF00568.25: WH1; WH1/EVH1 domain containing protein HyS0057.46 HyS0057.046 12 (cutoff = 1) male specific - 4 yes - 2.32613 0 1.66333 0 0 0 226.044 159.162 0.997365 0 192.603 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 1 0 1 PREDICTED: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1-like [Hydra vulgaris] 3.50E-12 XP_012559677.1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Homo sapiens 61.2 91 1.84E-10 28.682 NP_066550 NA NA NA NA NA PF00027.31: cNMP_binding; cyclic nucleotide-binding domain containing protein HyS0007.291 HyS0007.291 13 (cutoff = 1) male specific - 4 yes - 0.639653 0.432903 0 0 0.106559 0.202084 133.502 97.5493 0.268139 0.1543215 115.52565 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 1 0 1 no hits - - no hits - - - - - - NA NA NA NA NA - unknown function HyS0057.47 HyS0057.047 14 (cutoff = 1) male specific - 4 yes - 0 0 0 0 0 0 70.1275 65.5001 0 0 67.8138 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 1 0 1 PREDICTED: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1-like [Hydra vulgaris] 2.60E-35 XP_012557623.1 "I-h channel, isoform H " Drosophila melanogaster 117 76 1.21E-29 44 NP_001137669 Hyperpolarization-activated cyclic nucleotide-modulated cation channel splice variant ABL-II NA ion channel activity potassium ion transmembrane transport integral component of membrane PF00520.33: Ion_trans; PF08412.12: Ion_trans_N; PF18380.3: GEN1_C; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel HyS0067.10 HyS0067.010 15 (cutoff = 1) male specific sex-linked-abnormal 4 yes - 0 0.649008 0 0 0 0 26.3407 34.1806 0.162252 0 30.26065 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 1 0 1 no hits - - JNK-interacting protein Caenorhabditis elegans 40.4 53 0.004 30.38 NP_001293608 NA NA NA NA NA PF01496.21: V_ATPase_I; PF13476.8: AAA_23; PF00038.23: Filament; PF11559.10: ADIP; PF04108.14: ATG17_like; PF11068.10: YlqD; PF06785.13: UPF0242; PF08702.12: Fib_alpha; PF16515.7: HIP1_clath_bdg; PF09548.12: Spore_III_AB; PF17749.3: MIP-T3_C; PF08203.13: RNA_polI_A14; PF06818.17: Fez1; PF10234.11: Cluap1; PF05791.13: Bacillus_HBL; PF12325.10: TMF_TATA_bd; PF06148.13: COG2; PF02403.24: Seryl_tRNA_N; PF02601.17: Exonuc_VII_L; PF14854.8: LURAP; PF04163.14: Tht1; PF07889.14: DUF1664; PF05531.14: NPV_P10; PF14182.8: YgaB; PF05837.14: CENP-H; PF11744.10: ALMT; PF08286.13: Spc24; PF03961.15: FapA; PF06156.15: YabA; PF18504.3: Csm1_N; PF12732.9: YtxH; PF16566.7: CREPT; PF04859.14: DUF641; PF14584.8: DUF4446; PF06295.14: DUF1043; unknown function HyS0070.23 HyS0070.023 16 (cutoff = 1) male specific sex-linked-abnormal - - - 0 1.27555 0.543523 0 0 0 31.649 24.0599 0.45476825 0 27.85445 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 1 0 1 no hits - - no hits - - - - - - NA NA NA NA NA PF05110.15: AF-4; PF00969.21: MHC_II_beta; PF05477.13: SURF2; PF04641.14: Rtf2; PF02535.24: Zip; PF15434.8: FAM104; unknown function HyS0070.81 HyS0070.081 17 (cutoff = 1) male specific sex-linked-abnormal - - - 0.268242 0 0 0 0 0 23.1616 14.417 0.0670605 0 18.7893 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 1 0 1 no hits - - no hits - - - - - - NA NA NA NA NA - unknown function HyS0113.16 HyS0113.016 18 (cutoff = 1) male specific sex-linked-abnormal 4 yes yes 0.743922 0 0 2.28508 0 0 7.67181 5.15443 0.7572505 0 6.41312 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 1 0 1 hypothetical protein BSL78_23407 [Apostichopus japonicus] 6.80E-22 PIK39749.1 no hits - - - - - - NA NA NA NA NA PF10906.10: Mrx7; unknown function HyS0067.3 HyS0067.003 19 (cutoff = 1) male specific sex-linked-abnormal 4 yes - 0 0 0 1.79491 0.0582572 0 6.35108 4.99763 0.4487275 0.0291286 5.674355 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 1 0 1 uncharacterized protein LOC110234234 [Exaiptasia pallida] 5.30E-56 XP_020895260.1 uncharacterized protein si:ch73-7i4.2 Danio rerio 143 32 4.06E-34 31.799 XP_002663431 NA NA NA NA NA PF18758.3: KDZ; PF08491.12: SE; PF18804.3: CxC3; likely KDZ transposase HyS0113.15 HyS0113.015 20 (cutoff = 1) male specific sex-linked-abnormal 4 yes yes 0 0 0 0 0 0 5.89509 3.32476 0 0 4.609925 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105850180 [Hydra vulgaris] 5.50E-34 XP_012566116.1 uncharacterized protein si:ch1073-366l7.1 isoform X1 Danio rerio 62.8 19 1.57E-08 27.072 XP_009292747 NA NA NA NA NA PF06378.13: DUF1071; unknown function HyS0067.73 HyS0067.073 21 (cutoff = 1) male specific sex-linked-abnormal 4 yes - 0 0 0 0 0 0 3.38389 5.35899 0 0 4.37144 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC111194822 [Astyanax mexicanus] 3.80E-11 XP_022535652.1 no hits - - - - - - NA NA NA NA NA PF03638.17: TCR; unknown function HyS0069.15 HyS0069.015 22 (cutoff = 1) male specific sex-linked-abnormal - - - 0.45084 0 0.325286 1.22969 0.67595 0.356139 5.29848 4.20156 0.501454 0.5160445 4.75002 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 ATP-dependent DNA helicase pif1 [Symbiodinium microadriaticum] 3.00E-18 OLP87736.1 ATP-dependent DNA helicase PIF1 Glycine max 46.6 56 4.96E-04 22.684 XP_025980870 NA NA NA NA NA PF13604.8: AAA_30; PF13245.8: AAA_19; PF05970.16: PIF1; PF00004.31: AAA; PF18335.3: SH3_13; PF13238.8: AAA_18; PF13401.8: AAA_22; PF07728.16: AAA_5; PF01926.25: MMR_HSR1; PF13191.8: AAA_16; ATP-dependent helicase-like HyS0007.328 HyS0007.328 23 (cutoff = 1) male specific - 4 yes - 0 0 0.368055 0.692364 0 0.484627 4.71353 2.80206 0.26510475 0.2423135 3.757795 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 no hits - - centromere protein C isoform 1 Homo sapiens 43.5 33 0.001 35.802 NP_001803 NA NA NA NA NA PF11699.10: CENP-C_C; PF07883.13: Cupin_2; PF06865.13: Ppnp; PF05899.14: Cupin_3; cupin-domain containing protein HyS0057.18 HyS0057.018 24 (cutoff = 1) male specific - 4 yes - 0 0 0 0 0 0 3.01658 3.58052 0 0 3.29855 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE7421 [Exaiptasia pallida] 6.30E-10 KXJ19625.1 no hits - - - - - - NA NA NA NA NA - unknown function HyS0067.71 HyS0067.071 25 (cutoff = 1) male specific sex-linked-abnormal 4 yes - 0 0 0 2.37392 0 0 3.18713 2.52226 0.59348 0 2.854695 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110040545 [Orbicella faveolata] 7.60E-07 XP_020601443.1 no hits - - - - - - NA NA NA NA NA - unknown function HyS4443.1 HyS4443.001 26 (cutoff = 1) male specific sex-linked-abnormal - - - 0.393124 0.399646 0.42558 0.268269 0.261963 0.0621123 2.25269 2.14369 0.37165475 0.16203765 2.19819 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 predicted protein [Nematostella vectensis] 1.40E-11 XP_001623703.1 no hits - - - - - - NA NA NA NA NA PF02283.18: CobU; unknown function HyS0057.124 HyS0057.124 27 (cutoff = 1) male specific - 4 yes yes 0 0 0 0 0 0.174442 2.86523 0.756973 0 0.087221 1.8111015 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 "COUP-TF protein, partial [Hydractinia echinata]" 3.80E-72 AEB21388.1 COUP transcription factor 2 isoform X1 Mus musculus 196 81 1.80E-61 47.895 XP_006540640 Ligand-binding domain of nuclear hormone receptor NA steroid hormone receptor activity steroid hormone mediated signaling pathway nucleus PF00104.32: Hormone_recep; PF07619.13: DUF1581; COUP-TF-like nuclear hormone receptor HyS0057.129 HyS0057.129 28 (cutoff = 1) male specific - 4 yes - 0 0.170122 0.724724 0.342314 0.167373 0.0793623 2.16084 1.48497 0.30929 0.12336765 1.822905 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 "COUP-TF protein, partial [Hydractinia echinata]" 2.70E-175 AEB21388.1 nuclear receptor subfamily 2 group F member 1-A Danio rerio 364 81 4.13E-122 48.285 NP_571255 COUP transcription factor 2 NR2F6 steroid hormone receptor activity steroid hormone mediated signaling pathway nucleus PF00104.32: Hormone_recep; PF00105.20: zf-C4; COUP-TF-like nuclear hormone receptor HyS0069.70 HyS0069.070 29 (cutoff = 1) male specific sex-linked-abnormal - - - 0 0 0 0 0 0 1.0121 2.27372 0 0 1.64291 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 hypothetical protein pdam_00024985 [Pocillopora damicornis] 5.20E-34 RMX56021.1 uncharacterized protein si:ch211-174j14.2 Danio rerio 41.6 14 0.009 33.333 XP_002662443 NA NA NA NA NA PF11596.10: DUF3246; unknown function HyS1036.1 HyS1036.001 30 (cutoff = 1) male specific sex-linked-abnormal 4 - - 0 0.115429 0 0 0.397109 0.215222 0.390102 3.24835 0.02885725 0.3061655 1.819226 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 PREDICTED: U3 small nucleolar ribonucleoprotein protein MPP10-like [Hydra vulgaris] 3.20E-107 XP_012558082.1 U3 small nucleolar ribonucleoprotein protein MPP10 Danio rerio 270 54 2.23E-80 50.453 NP_001292472 U3 small nucleolar ribonucleoprotein MPP10 M phase phosphoprotein 10 MPHOSPH10 NA rRNA processing Mpp10 complex PF04006.14: Mpp10; "U3 small nucleolar ribonucleoprotein complex, subunit MPP10" HyS0070.5 HyS0070.005 31 (cutoff = 1) male specific sex-linked-abnormal - - - 0 0.548011 0 0 0 0 1.41392 1.49357 0.13700275 0 1.453745 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 PREDICTED: ankyrin-3-like [Hydra vulgaris] 4.40E-04 XP_012560619.1 "transient receptor potential cation channel, subfamily N, member 1 " Danio rerio 55.5 87 1.45E-08 32.258 NP_899192 Transient receptor potential cation channel subfamily A member 1-like NA ion channel activity ion transmembrane transport integral component of membrane PF13637.8: Ank_4; PF12796.9: Ank_2; PF13606.8: Ank_3; PF13857.8: Ank_5; PF00023.32: Ank; PF05034.15: MAAL_N; ankyrin repeat containing protein HyS0116.7 HyS0116.007 32 (cutoff = 1) male specific sex-linked-abnormal 4 yes - 0.319184 1.08205 0.806532 1.52617 1.22298 0.605198 2.74187 1.66708 0.933484 0.914089 2.204475 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110050834 isoform X1 [Orbicella faveolata] 2.50E-60 XP_020612464.1 G2/M phase-specific E3 ubiquitin-protein ligase-like Danio rerio 85.5 44 7.33E-16 24.43 XP_017209386 NA NA NA NA NA PF00632.27: HECT; PF12895.9: ANAPC3; HECT domain containing protein HyS0069.45 HyS0069.045 33 (cutoff = 1) male specific sex-linked-abnormal - - - 0 0 0 0 0 0 0.702454 1.6686 0 0 1.185527 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF08126.13: Propeptide_C25; PF18113.3: Rbx_binding; unknown function HyS0057.71 HyS0057.071 34 (cutoff = 1) male specific - 4 yes - 0.685492 0.464709 0.371131 1.17023 0.0570983 0.054155 1.47241 0.934145 0.6728905 0.05562665 1.2032775 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 "hypothetical protein TSAR_010977, partial [Trichomalopsis sarcophagae]" 4.20E-43 OXU22397.1 no hits - - - - - - NA NA NA NA NA PF02739.18: 5_3_exonuc_N; CXC domain containing protein-like HyS0067.4 HyS0067.004 35 (cutoff = 1) male specific sex-linked-abnormal 4 yes - 0 0 0.23234 0 0 0 1.85069 0.293467 0.058085 0 1.0720785 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 "Methylmalonic aciduria and homocystinuria type D-like, mitochondrial [Exaiptasia pallida]" 6.10E-05 KXJ29677.1 HTH CENPB-type domain-containing protein Caenorhabditis elegans 42 19 0.004 37.143 NP_490670 BrkDBD domain-containing protein NA DNA binding NA NA PF09607.12: BrkDBD; PF05207.15: zf-CSL; Brinker DNA-binding domain containing protein HyS0007.327 HyS0007.327 36 (cutoff = 1) male specific - 4 yes - 0 0 0 0 0 0 2.04785 0 0 0 1.023925 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF01949.18: DUF99; unknown function HyS0070.97 HyS0070.097 37 (cutoff = 1) male specific sex-linked-abnormal - - - 1.03392 1.39634 0.74394 0.699665 0.172236 0.163267 1.19108 0.944078 0.96846625 0.1677515 1.067579 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF07466.13: DUF1517; unknown function HyS0057.113 HyS0057.113 38 (cutoff = 1) male specific - 4 yes - 0.316056 0.32144 0.912729 0.215896 0.579172 0.449451 1.53846 1.00477 0.44153025 0.5143115 1.271615 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 putative SCAN domain-containing protein 3-like [Apostichopus japonicus] 2.30E-37 PIK39696.1 "nucleolar protein 4-like isoform X4, partial " Danio rerio 74.7 24 1.28E-13 32.24 XP_021329283 NA NA NA NA NA PF17921.3: Integrase_H2C2; similar to SCAN-domain containing protein HyS2624.1 HyS2624.001 39 (cutoff = 5) female specific sex-linked-abnormal - - - 4.22143 2.60102 2.90828 0 231.05 191.483 3.51825 0.261565 2.4326825 211.2665 1.8899075 1 1 1 0 0 1 0 0 0 0 1 0 0 0 0 1 1 0 no hits - - no hits - - - - - - NA NA NA NA NA PF10948.10: DUF2635; PF00084.22: Sushi; PF18054.3: CEL_III_C; unknown function HyS0007.282 HyS0007.282 40 (cutoff = 5) female specific - 4 yes - 0 2.09152 0 1.38673 36.6424 26.8513 1.80951 0.477696 0.8695625 31.74685 1.143603 0 1 1 0 0 0 1 0 0 0 1 0 0 0 0 1 1 0 no hits - - no hits - - - - - - NA NA NA NA NA - unknown function HyS0069.11 HyS0069.011 41 (cutoff = 5) female specific sex-linked-abnormal - - - 6.18161 2.04129 2.17508 0 24.4348 28.9477 3.66859 0 2.599495 26.69125 1.834295 1 1 1 0 0 1 0 0 0 0 1 0 0 0 0 1 1 0 no hits - - no hits - - - - - - NA NA NA NA NA - unknown function HyS0918.1 HyS0918.001 42 (cutoff = 5) female specific sex-linked-abnormal - - - 6.11097 5.5802 2.29168 2.41085 15.2314 15.4874 3.69903 4.6406 4.098425 15.3594 4.169815 1 1 1 0 0 1 0 0 0 0 1 0 0 0 0 1 1 0 PREDICTED: casein kinase I isoform gamma-3-like [Hydra vulgaris] 9.70E-169 XP_002167421.3 casein kinase I isoform gamma-3 isoform 8 Homo sapiens 565 37 0 81.931 NP_001351069 casein kinase I CSNK1G1 protein serine/threonine kinase activity protein phosphorylation nucleus PF03114.20: BAR; PF06244.14: Ccdc124; PF00069.27: Pkinase; PF07714.19: PK_Tyr_Ser-Thr; PF00018.30: SH3_1; PF17667.3: Pkinase_fungal; PF14604.8: SH3_9; PF07653.19: SH3_2; PF02729.23: OTCace_N; kinase-BAR domain-SH3-coiled coil domain containing protein HyS0148.2 HyS0148.002 43 (cutoff = 5) female specific sex-linked-abnormal - - - 4.95683 2.08955 2.22696 3.34542 11.353 9.19505 2.85995 2.54981 3.15469 10.274025 2.70488 1 1 1 0 0 1 0 0 0 0 1 0 0 0 0 1 1 0 "PREDICTED: uncharacterized protein LOC105845569, partial [Hydra vulgaris]" 2.00E-11 XP_012558924.1 no hits - - - - - - NA NA NA NA NA - unknown function HyS4472.1 HyS4472.001 44 (cutoff = 5) female specific sex-linked-abnormal - - - 0.651263 1.43503 4.23153 1.33445 6.29268 4.57919 0 0.073949 1.91306825 5.435935 0.0369745 1 1 0 0 1 0 0 0 0 0 1 0 0 0 0 1 1 0 PREDICTED: gamma-glutamyltranspeptidase 1-like [Hydra vulgaris] 2.90E-175 XP_012556244.1 gamma-glutamyltranspeptidase 1-like Danio rerio 415 88 4.25E-137 40.399 XP_697468 Gamma-glutamyltranspeptidase NA glutathione hydrolase activity glutathione catabolic process integral component of membrane PF01019.23: G_glu_transpept; PF01456.19: Mucin; PF06791.15: TMP_2; PF13908.8: Shisa; gamma-glutamyltranspeptidase HyS0067.50 HyS0067.050 45 (cutoff = 5) female specific sex-linked-abnormal 4 yes - 3.97002 3.07192 0.613467 0 5.66884 4.74849 0.650891 0.516095 1.91385175 5.208665 0.583493 1 1 0 0 1 0 0 0 0 0 1 0 0 0 0 1 1 0 PREDICTED: fibroblast growth factor receptor-like isoform X2 [Hydra vulgaris] 6.00E-110 XP_012555850.1 fibroblast growth factor receptor-like 1 isoform 1 precursor Mus musculus 82 88 1.45E-15 22.222 NP_473412 NA NA NA NA NA PF13927.8: Ig_3; PF07679.18: I-set; PF00047.27: ig; PF13895.8: Ig_2; PF07686.19: V-set; PF18452.3: Ig_6; PF16681.7: Ig_5; PF17736.3: Ig_C17orf99; PF16680.7: Ig_4; PF16706.7: Izumo-Ig; FGF-receptor/Basigin-like protein HyS0067.52 HyS0067.052 46 (cutoff = 5) female specific sex-linked-abnormal 4 yes - 2.71559 2.45307 4.08189 2.16029 5.80567 5.50592 0.518948 1.54317 2.85271 5.655795 1.031059 1 1 1 0 0 1 0 0 0 0 1 0 0 0 0 1 1 0 PREDICTED: fibroblast growth factor receptor-like isoform X2 [Hydra vulgaris] 7.80E-110 XP_012555850.1 fibroblast growth factor receptor-like 1 isoform 1 precursor Mus musculus 82 88 1.41E-15 22.222 NP_473412 NA NA NA NA NA PF13927.8: Ig_3; PF07679.18: I-set; PF00047.27: ig; PF13895.8: Ig_2; PF07686.19: V-set; PF18452.3: Ig_6; PF17736.3: Ig_C17orf99; PF16706.7: Izumo-Ig; PF16680.7: Ig_4; FGF-receptor/Basigin-like protein HyS0007.322 HyS0007.322 47 (cutoff = 5) female specific - 4 yes - 3.45186 3.44404 3.66685 1.80581 9.57289 6.48145 3.65949 4.79131 3.09214 8.02717 4.2254 1 1 1 0 0 1 0 0 0 0 1 0 0 0 0 1 1 0 PREDICTED: importin-11 [Hydra vulgaris] 2.20E-259 XP_012554114.1 importin-11 isoform 1 Homo sapiens 595 99 0 35.53 NP_001128251 Importin N-terminal domain-containing protein NA Ran GTPase binding intracellular protein transport nucleus PF03810.21: IBN_N; importin-11 like HyS0007.412 HyS0007.412 48 (cutoff = 5) male specific - 4 yes - 2.2507 0.45746 0.324782 8.28758 0.374945 0.426704 1137.92 749.988 2.8301305 0.4008245 943.954 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: uncharacterized protein LOC105845477 [Hydra vulgaris] 3.10E-05 XP_012558738.1 no hits - - - - - - NA NA NA NA NA - unknown function HyS0057.61 HyS0057.061 49 (cutoff = 5) male specific - 4 yes - 0.925144 0 2.99706 4.38861 0 0 1042.74 676.531 2.0777035 0 859.6355 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: E3 ubiquitin-protein ligase MARCH2-like [Hydra vulgaris] 2.70E-63 XP_004211600.1 E3 ubiquitin-protein ligase MARCHF2 isoform 1 Homo sapiens 147 74 2.60E-42 40 NP_001005415 Membrane associated ring-CH-type finger 2 2-Mar zinc ion binding protein ubiquitination cytoplasmic vesicle PF12906.9: RINGv; PF14800.8: DUF4481; PF13639.8: zf-RING_2; PF05290.13: Baculo_IE-1; PF19291.1: DUF5911; PF07535.14: zf-DBF; PF00097.27: zf-C3HC4; PF12678.9: zf-rbx1; PF17120.7: Zn_ribbon_17; PF11793.10: FANCL_C; E3 ubiquitin-protein ligase MARCHF2/3-like HyS0057.48 HyS0057.048 50 (cutoff = 5) male specific - 4 yes - 0 0 0 11.3653 0.079359 0 531.153 531.866 2.841325 0.0396795 531.5095 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, partial [Charadrius vociferus]" 1.00E-60 KGM00411.1 "I-h channel, isoform I " Drosophila melanogaster 269 73 1.94E-82 41.495 NP_001033946 Hyperpolarization-gated and cyclic nucleotide regulated channel NA ion channel activity potassium ion transmembrane transport HCN channel complex PF00027.31: cNMP_binding; PF09930.11: DUF2162; PF00520.33: Ion_trans; PF15870.7: EloA-BP1; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel HyS0057.36 HyS0057.036 51 (cutoff = 5) male specific - 4 yes - 0.824007 0 0 16.2152 0.274539 0.260287 488.513 463.144 4.25980175 0.267413 475.8285 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 no hits - - no hits - - - - - - NA NA NA NA NA - unknown function HyS0070.65 HyS0070.065 52 (cutoff = 5) male specific sex-linked-abnormal - - - 0.551517 0.373441 0.397737 6.38479 0.091877 0 398.869 355.034 1.92687125 0.0459385 376.9515 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: protein DBF4 homolog B-like [Acropora digitifera] 4.90E-24 XP_015769944.1 protein DBF4 homolog B isoform 2 Homo sapiens 95.5 62 2.76E-20 28.523 NP_079380 NA NA NA NA NA PF07535.14: zf-DBF; PF00533.28: BRCT; PF12874.9: zf-met; PF00615.21: RGS; PF12738.9: PTCB-BRCT; PF16589.7: BRCT_2; PF06220.14: zf-U1; DBF4 zinc finger-like protein HyS0007.262 HyS0007.262 53 (cutoff = 5) male specific - 4 yes - 1.09904 1.67704 3.27371 3.94356 4.02799 3.47324 220.132 168.47 2.4983375 3.750615 194.301 1 1 1 0 0 1 0 0 0 0 0 1 0 0 0 1 0 1 uncharacterized protein LOC110065996 [Orbicella faveolata] 8.70E-69 XP_020628842.1 no hits - - - - - - NA NA NA NA NA PF15373.8: DUF4601; Testis-Expressed Protein 45-like HyS0057.16 HyS0057.016 54 (cutoff = 5) male specific - 4 yes - 3.22334 6.54826 3.29336 2.56137 3.22185 2.88556 37.7545 27.1261 3.9065825 3.053705 32.4403 1 1 1 0 0 1 0 0 0 0 0 1 0 0 0 1 0 1 protein FAM221B-like [Dendronephthya gigantea] 2.40E-91 XP_028396751.1 protein FAM221B Mus musculus 226 56 1.31E-68 51.546 NP_780726 PWWP domain-containing protein NA serine-type endopeptidase inhibitor activity negative regulation of endopeptidase activity integral component of membrane PF14753.8: FAM221; Protein FAM221B-like HyS0070.25 HyS0070.025 55 (cutoff = 5) male specific sex-linked-abnormal - - - 1.51787 0 5.44819 6.12444 2.02231 1.43724 31.1604 30.9482 3.272625 1.729775 31.0543 1 1 1 0 0 1 0 0 0 0 0 1 0 0 0 1 0 1 no hits - - no hits - - - - - - NA NA NA NA NA PF17727.3: CtsR_C; unknown function HyS0113.24 HyS0113.024 56 (cutoff = 5) male specific sex-linked-abnormal 4 yes - 0 0.476892 1.26998 16.7676 0.11743 0 14.3758 10.4342 4.628618 0.058715 12.405 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 "hypothetical protein M513_02985, partial [Trichuris suis]" 1.50E-15 KFD56207.1 tissue factor pathway inhibitor isoform b precursor Mus musculus 69.3 43 1.65E-12 32.231 NP_001170790 NA NA NA NA NA PF00014.25: Kunitz_BPTI; Pancreatic trypsin inhibitor Kunitz domain containing protein HyS0057.114 HyS0057.114 57 (cutoff = 5) male specific - 4 yes - 4.42394 0.213868 1.8224 2.14962 0.210566 0.199665 14.5138 8.34295 2.152457 0.2051155 11.428375 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: uncharacterized protein LOC109593289 [Amphimedon queenslandica] 3.80E-10 XP_019863997.1 bromodomain adjacent to zinc finger domain protein 2A isoform 2 Homo sapiens 42.7 15 0.006 31.25 NP_001287834 NA NA NA NA NA PF00628.31: PHD; PF03107.18: C1_2; PF13771.8: zf-HC5HC2H; PF02892.17: zf-BED; zinc-finger domain containing protein HyS0007.257 HyS0007.257 58 (cutoff = 5) male specific - 4 yes - 2.53811 1.89093 1.09847 1.03765 0.507387 1.44351 10.0446 12.8129 1.64129 0.9754485 11.42875 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 "PREDICTED: beta-1,3-galactosyltransferase sqv-2-like [Hydra vulgaris]" 9.00E-91 XP_002158539.1 "beta-1,3-galactosyltransferase 1 " Mus musculus 45.4 57 7.52E-04 24.735 NP_001366253 NA NA NA NA NA PF01762.23: Galactosyl_T; "Glycosyl transferase, family 31" HyS0120.42 HyS0120.042 59 (cutoff = 5) male specific sex-linked-abnormal 4 yes - 0 1.81284 4.63623 5.08534 0.536783 0.169606 9.90221 8.58426 2.8836025 0.3531945 9.243235 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: mitogen-activated protein kinase kinase kinase 12-like [Hydra vulgaris] 1.00E-27 XP_012556077.1 "PR/SET domain containing protein 7, isoform D " Drosophila melanogaster 92 44 5.08E-20 42.342 NP_001247100 Histone-lysine N-methyltransferase LOC108267344 methyltransferase activity methylation nucleus PF00856.30: SET; SET domain containing protein HyS0007.368 HyS0007.368 60 (cutoff = 5) male specific - 4 yes - 2.55561 1.53387 7.31343 2.01746 0.0982485 0.372779 10.291 6.86861 3.3550925 0.23551375 8.579805 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 A disintegrin and metalloproteinase with thrombospondin motifs 6-like isoform X1 [Stylophora pistillata] 1.70E-79 XP_022780571.1 thrombospondin type-1 domain-containing protein 4 isoform b precursor Mus musculus 197 36 6.98E-52 32.979 NP_766032 NA NA NA NA NA PF19030.2: TSP1_ADAMTS; PF00090.21: TSP_1; PF19028.2: TSP1_spondin; PF19035.2: TSP1_CCN; PF08686.13: PLAC; Thrombospondin repeat domain containing protein HyS0067.49 HyS0067.049 61 (cutoff = 5) male specific sex-linked-abnormal 4 yes - 0.94053 1.51524 0.59438 0.160788 2.31109 2.04353 9.95779 11.0459 0.8027345 2.17731 10.501845 0 1 1 0 0 0 1 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: uncharacterized protein LOC100213999 [Hydra vulgaris] 8.70E-140 XP_012555849.1 ankyrin repeat and LEM domain-containing protein 1 Danio rerio 241 50 3.09E-66 44.863 NP_999909 LOW QUALITY PROTEIN: ankyrin repeat and LEM domain-containing protein 1 ANKLE1 endonuclease activity nucleic acid phosphodiester bond hydrolysis nucleus PF13637.8: Ank_4; PF03020.17: LEM; PF12796.9: Ank_2; PF00023.32: Ank; PF13606.8: Ank_3; PF13857.8: Ank_5; PF16268.7: DUF4921; Ankyrin repeat and LEM domain-containing protein HyS0070.83 HyS0070.083 62 (cutoff = 5) male specific sex-linked-abnormal - - - 1.73705 5.41187 3.651 1.29713 0.105229 0.349367 7.72209 9.27671 3.0242625 0.227298 8.4994 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: patched domain-containing protein 3-like [Acropora digitifera] 1.20E-163 XP_015754311.1 patched domain-containing protein 3 isoform X2 Danio rerio 299 93 8.79E-87 27.211 XP_021327233 Patched domain-containing protein 3 PTCHD3 transporter activity transport integral component of membrane PF02460.20: Patched; PF12349.10: Sterol-sensing; PF03176.17: MMPL; PF02513.19: Spin-Ssty; Protein patched/dispatched family member HyS0067.65 HyS0067.065 63 (cutoff = 5) male specific sex-linked-abnormal 4 yes - 1.48702 1.37628 1.66058 1.01819 0.0450409 0.491351 8.34863 6.95906 1.3855175 0.26819595 7.653845 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: alpha-1-macroglobulin-like [Hydra vulgaris] 3.40E-198 XP_012564458.1 alpha-2-macroglobulin isoform c Homo sapiens 553 62 2.19E-171 35.415 NP_001334354 Alpha-2-macroglobulin splice variant 1 NA endopeptidase inhibitor activity negative regulation of endopeptidase activity extracellular space PF07678.16: TED_complement; PF00207.24: A2M; PF07703.16: A2M_BRD; PF07677.16: A2M_recep; PF17789.3: MG4; PF05326.13: SVA; PF01835.21: MG2; alpha-2 macroglobulin-like HyS0007.261 HyS0007.261 64 (cutoff = 5) male specific - 4 yes - 0.83189 1.4093 3.00158 1.41879 0.207877 0.19715 7.62849 7.37266 1.66539 0.2025135 7.500575 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 "PREDICTED: steroid 17-alpha-hydroxylase/17,20 lyase-like isoform X1 [Acropora digitifera]" 8.40E-112 XP_015779092.1 "steroid 17-alpha-hydroxylase/17,20 lyase precursor " Danio rerio 342 90 7.52E-111 38.983 NP_997971 17a-hydroxylase/lyase NA "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" oxidation-reduction process integral component of membrane PF00067.24: p450; "Cytochrome P450, E-class, group I" HyS0057.88 HyS0057.088 65 (cutoff = 5) male specific - 4 yes yes 0.815898 0.275815 2.93834 7.19809 0 0.386591 6.56783 6.13644 2.80703575 0.1932955 6.352135 1 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: uncharacterized protein LOC100201999 [Hydra vulgaris] 6.30E-24 XP_002164179.2 no hits - - - - - - NA NA NA NA NA PF00240.25: ubiquitin; PF18396.3: TBK1_ULD; PF14560.8: Ubiquitin_2; PF11620.10: GABP-alpha; PF18037.3: Ubiquitin_5; Ubiquitin domain containing protein HyS0070.60 HyS0070.060 66 (cutoff = 5) male specific sex-linked-abnormal - - - 4.45689 2.6461 7.17727 5.20989 2.75337 2.49438 7.70201 8.00453 4.8725375 2.623875 7.85327 1 1 1 0 0 1 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: phosphatidylinositide phosphatase SAC2-like [Hydra vulgaris] 9.70E-301 XP_012554475.1 phosphatidylinositide phosphatase SAC2 isoform X1 Danio rerio 694 75 0 46.211 XP_005156933 Phosphatidylinositide phosphatase INPP5F phosphoric ester hydrolase activity regulation of endocytic recycling clathrin-coated endocytic vesicle PF02383.20: Syja_N; PF12456.10: hSac2; phosphatidylinositide phosphatase SAC2 HyS0244.4 HyS0244.004 67 (cutoff = 5) male specific sex-linked-abnormal - - - 2.69217 1.99816 6.98989 3.33967 2.07428 1.88786 7.74751 5.83956 3.7549725 1.98107 6.793535 1 1 1 0 0 1 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: elongation factor Tu GTP-binding domain-containing protein 1 [Hydra vulgaris] 0 XP_012558752.1 elongation factor-like GTPase 1 Danio rerio 1244 100 0 52.936 XP_697184 Elongation factor Tu GTP-binding domain-containing protein 1 EFL1 GTPase activity translational elongation cytosol PF00009.29: GTP_EFTU; PF00679.26: EFG_C; PF03144.27: GTP_EFTU_D2; PF03764.20: EFG_IV; PF14492.8: EFG_III; PF01926.25: MMR_HSR1; elongation factor-like GTPase 1 HyS1699.2 HyS1699.002 68 (cutoff = 5) male specific sex-linked-abnormal 4 yes - 2.5785 3.27192 4.6468 6.13827 2.36253 2.44386 5.367 6.30953 4.1588725 2.403195 5.838265 1 1 1 0 0 1 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: fanconi-associated nuclease 1-like [Hydra vulgaris] 3.00E-92 XP_012557644.1 fanconi-associated nuclease 1 isoform X5 Homo sapiens 226 86 4.40E-69 37.898 XP_016877501 Fanconi-associated nuclease FAN1 phosphodiesterase I activity interstrand cross-link repair nucleus PF08774.13: VRR_NUC; PF19710.1: PIK3CG_ABD; Fanconi-associated nuclease 1-like HyS0007.387 HyS0007.387 69 (cutoff = 5) male specific - 4 yes - 2.29011 1.9658 2.43353 4.15084 2.8277 3.19331 6.70185 3.48268 2.71007 3.010505 5.092265 1 1 1 0 0 1 0 0 0 0 0 1 0 0 0 1 0 1 PREDICTED: DNA topoisomerase 3-alpha-like [Hydra vulgaris] 2.60E-246 XP_012563421.1 DNA topoisomerase 3-alpha isoform 1 Homo sapiens 717 58 0 51.009 NP_004609 DNA topoisomerase TOP3A DNA topoisomerase type I activity DNA topological change chromosome PF01131.22: Topoisom_bac; PF06839.14: zf-GRF; PF01751.24: Toprim; PF01396.21: zf-C4_Topoisom; PF13662.8: Toprim_4; DNA topoisomerase 3-like HyS0070.70 HyS0070.070 70 (cutoff = 5) male specific sex-linked-abnormal - - - 4.4226 3.39214 6.18132 3.15753 3.81197 3.85899 5.94035 5.58396 4.2883975 3.83548 5.762155 1 1 1 0 0 1 0 0 0 0 0 1 0 0 0 1 0 1 F-box/LRR-repeat protein 20-like [Stylophora pistillata] 1.20E-64 XP_022797769.1 F-box/LRR-repeat protein 7 Danio rerio 83.2 45 4.50E-15 27.374 XP_001344855 NA NA NA NA NA PF13923.8: zf-C3HC4_2; PF00097.27: zf-C3HC4; PF13639.8: zf-RING_2; PF12560.10: RAG1_imp_bd; PF14835.8: zf-RING_6; PF13445.8: zf-RING_UBOX; PF12678.9: zf-rbx1; PF13920.8: zf-C3HC4_3; PF14634.8: zf-RING_5; PF13516.8: LRR_6; PF11789.10: zf-Nse; PF15227.8: zf-C3HC4_4; PF16685.7: zf-RING_10; PF18595.3: DHR10; PF04201.17: TPD52; PF12861.9: zf-ANAPC11; PF12799.9: LRR_4; PF14447.8: Prok-RING_4; PF17120.7: Zn_ribbon_17; F-box and LRR domain containing protein HyS0057.126 HyS0057.126 71 - - 4 yes - 0.446676 0.605264 0.322288 0.304599 3.79501 8.46843 12.4192 13.9093 0.41970675 6.13172 13.16425 0 1 1 0 0 0 1 0 0 0 1 1 0 0 0 1 0 0 PREDICTED: nuclear receptor subfamily 2 group F member 1-B-like [Hydra vulgaris] 7.90E-138 XP_012567198.1 COUP transcription factor 2 Danio rerio 509 80 9.07E-179 66.31 NP_571258 Ovalbumin upstream promoter-transcription factor I NA steroid hormone receptor activity steroid hormone mediated signaling pathway nucleus PF00104.32: Hormone_recep; PF00105.20: zf-C4; PF09726.11: Macoilin; PF01080.19: Presenilin; - HyS0116.19 HyS0116.019 72 - sex-linked-abnormal 4 yes - 0.78952 0.535474 0.57015 0.719587 2.10443 2.66144 1.43114 0.896068 0.65368275 2.382935 1.163604 0 1 1 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: Golgi pH regulator-like [Hydra vulgaris] 6.30E-26 XP_002162878.1 Golgi pH regulator B isoform 3 Homo sapiens 106 22 1.51E-23 36.517 NP_001337112 Golgi pH regulator B NA voltage-gated ion channel activity lipid transport integral component of membrane PF12537.10: GPHR_N; PF00932.21: LTD; PF00038.23: Filament; PF02944.22: BESS; - HyS0070.13 HyS0070.013 73 - sex-linked-abnormal - - - 4.11272 5.54374 4.92416 2.77099 20.5504 14.9311 58.595 50.1962 4.3379025 17.74075 54.3956 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 PREDICTED: uncharacterized protein LOC100205151 [Hydra vulgaris] 7.70E-40 XP_012561309.1 hypothetical protein DDB_G0274661 Dictyostelium discoideum AX4 62 91 4.02E-11 27.711 XP_644129 NA NA NA NA NA PF08592.13: DUF1772; PF13493.8: DUF4118; - HyS0057.52 HyS0057.052 74 - - 4 yes - 1.67686 4.16306 3.82931 4.18663 10.7083 7.50554 16.5172 11.8251 3.463965 9.10692 14.17115 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 PREDICTED: galactose-3-O-sulfotransferase 2-like [Hydra vulgaris] 1.50E-76 XP_002153926.1 galactose-3-O-sulfotransferase 2-like isoform X1 Danio rerio 94.7 42 1.33E-19 38.202 XP_683950 Galactosylceramide sulfotransferase GAL3ST1 galactosylceramide sulfotransferase activity glycolipid biosynthetic process Golgi apparatus PF06990.13: Gal-3-0_sulfotr; PF00520.33: Ion_trans; PF03567.16: Sulfotransfer_2; - HyS0070.7 HyS0070.007 75 - sex-linked-abnormal - - - 4.47599 3.85505 5.84555 4.35932 8.40304 8.29742 12.8506 13.1212 4.6339775 8.35023 12.9859 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 PREDICTED: transient receptor potential cation channel subfamily A member 1-like [Hydra vulgaris] 4.00E-77 XP_012565640.1 transient receptor potential cation channel subfamily A member 1 isoform 1 Mus musculus 422 89 1.31E-127 30.046 NP_808449 NA NA NA NA NA PF12796.9: Ank_2; PF13637.8: Ank_4; PF00023.32: Ank; PF13606.8: Ank_3; PF13857.8: Ank_5; PF00520.33: Ion_trans; PF09026.12: CENP-B_dimeris; - HyS0007.385 HyS0007.385 76 - - 4 yes - 4.67425 2.07381 5.19512 5.04406 6.22953 4.63075 8.27864 6.11749 4.24681 5.43014 7.198065 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 PREDICTED: DNA topoisomerase 3-alpha-like [Hydra vulgaris] 0 XP_012563421.1 DNA topoisomerase 3-alpha Mus musculus 1031 76 0 55.895 NP_033436 DNA topoisomerase TOP3A DNA topoisomerase type I activity DNA topological change chromosome PF01131.22: Topoisom_bac; PF06839.14: zf-GRF; PF01751.24: Toprim; PF01429.21: MBD; PF14048.8: MBD_C; PF01396.21: zf-C4_Topoisom; PF16564.7: MBDa; PF13662.8: Toprim_4; - HyS0067.24 HyS0067.024 77 - sex-linked-abnormal 4 yes - 4.04711 1.52525 2.76074 3.38295 17.2299 16.1301 20.5218 16.123 2.9290125 16.68 18.3224 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 PREDICTED: centrosomal protein of 120 kDa-like [Hydra vulgaris] 5.00E-221 XP_002167810.3 centrosomal protein of 120 kDa isoform 1 Homo sapiens 698 99 0 41.159 NP_001362334 Centrosomal protein of 120 kDa CEP120 protein C-terminus binding positive regulation of centriole elongation centrosome PF12416.10: DUF3668; PF00168.32: C2; PF14924.8: DUF4497; - HyS0070.43 HyS0070.043 78 - sex-linked-abnormal - - - 3.44666 5.4448 4.55648 3.12857 8.70836 9.43763 5.76892 5.48901 4.1441275 9.072995 5.628965 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 PREDICTED: uncharacterized protein LOC105843193 [Hydra vulgaris] 1.90E-97 XP_012553652.1 MULTISPECIES: SDR family oxidoreductase Streptomyces 57.4 80 7.75E-08 24.684 WP_161270021 Chloroplast stem-loop binding of 41 kDa chloroplastic-like NA coenzyme binding galactose catabolic process via UDP-galactose cytosol PF01370.23: Epimerase; PF03435.20: Sacchrp_dh_NADP; PF04321.19: RmlD_sub_bind; PF18097.3: Vta1_C; - HyS0057.40 HyS0057.040 79 - - 4 yes - 4.64795 2.51236 5.019 4.40944 15.9504 15.2679 9.36241 9.7539 4.1471875 15.60915 9.558155 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 PREDICTED: E3 ubiquitin-protein ligase RNF220-like [Hydra vulgaris] 4.10E-38 XP_004208086.1 E3 ubiquitin-protein ligase RNF220 isoform 3 Homo sapiens 57 47 5.47E-08 30.827 NP_001363415 E3 ubiquitin-protein ligase RNF220 NA ubiquitin-protein transferase activity protein ubiquitination NA PF15926.7: RNF220; PF09788.11: Tmemb_55A; PF12269.10: CpG_bind_C; PF09798.11: LCD1; PF18608.3: XAF1_C; - HyS0067.47 HyS0067.047 80 - sex-linked-abnormal 4 yes - 3.64128 2.25939 1.75019 2.89084 12.5363 12.9422 5.05119 6.62894 2.635425 12.73925 5.840065 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF18332.3: XRN1_D1; PF05043.15: Mga; PF05149.14: Flagellar_rod; PF02183.20: HALZ; PF14817.8: HAUS5; PF11969.10: DcpS_C; PF06818.17: Fez1; PF00641.20: zf-RanBP; PF00170.23: bZIP_1; - HyS0070.85 HyS0070.085 81 - sex-linked-abnormal - - - 1.95689 2.65102 3.88207 2.00056 18.1744 13.8348 5.89163 8.00876 2.622635 16.0046 6.950195 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 PREDICTED: DUF21 domain-containing protein At4g14240-like [Hydra vulgaris] 1.20E-108 XP_012558724.1 CBS domain protein with a domain protein (DUF21) Arabidopsis thaliana 318 82 2.10E-103 45.408 NP_200091 Metal transporter CNNM NA NA cellular manganese ion homeostasis integral component of membrane PF01595.22: DUF21; PF00571.30: CBS; - HyS0070.72 HyS0070.072 82 - sex-linked-abnormal - - - 2.5833 4.5488 3.91292 5.27998 18.2469 15.753 6.81613 5.63974 4.08125 16.99995 6.227935 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 2-oxoglutarate and iron-dependent oxygenase JMJD4-like isoform X1 [Dendronephthya gigantea] 6.20E-94 XP_028392949.1 2-oxoglutarate and iron-dependent oxygenase JMJD4 Danio rerio 317 98 3.76E-104 41.646 NP_001070096 Proton-coupled amino acid transporter 4 JMJD4 2-oxoglutarate-dependent dioxygenase activity positive regulation of translational termination cytoplasm PF02373.24: JmjC; PF13621.8: Cupin_8; - HyS0070.64 HyS0070.064 83 - sex-linked-abnormal - - - 1.87995 3.7178 5.42914 4.28077 23.28 18.7634 5.11368 8.25318 3.826915 21.0217 6.68343 1 1 1 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 PREDICTED: ABC transporter G family member 22-like [Hydra vulgaris] 1.50E-190 XP_012560192.1 ABC transporter G family member 22 isoform X3 Glycine max 384 89 4.46E-124 36.86 XP_040863670 ATP-dependent ABC transporter NA ATPase activity abscisic acid transport integral component of membrane PF01061.26: ABC2_membrane; PF00005.29: ABC_tran; PF19055.2: ABC2_membrane_7; PF03193.18: RsgA_GTPase; PF13304.8: AAA_21; PF13555.8: AAA_29; PF02463.21: SMC_N; PF01926.25: MMR_HSR1; PF03215.17: Rad17; PF13401.8: AAA_22; PF13238.8: AAA_18; PF02224.20: Cytidylate_kin; PF13191.8: AAA_16; PF02263.21: GBP; PF13521.8: AAA_28; PF13604.8: AAA_30; PF13671.8: AAA_33; PF13481.8: AAA_25; PF00350.25: Dynamin_N; - HyS0007.390 HyS0007.390 84 - - 4 yes - 9123.35 6089.55 7593.54 9939.5 947.805 1663.34 5434.39 4724.72 8186.485 1305.5725 5079.555 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: 40S ribosomal protein S6-like [Hydra vulgaris] 4.20E-85 XP_004207839.1 40S ribosomal protein S6 Homo sapiens 369 99 1.22E-129 75.304 NP_001001 Small subunit ribosomal protein S6e NA structural constituent of ribosome translation ribosome PF01092.21: Ribosomal_S6e; - HyS0057.121 HyS0057.121 85 - - 4 yes - 8528.41 5502.31 6599.38 8895.8 1381.15 1957.03 4165.16 3901.68 7381.475 1669.09 4033.42 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 RecName: Full=60S ribosomal protein L17 5.80E-92 P37380.1 60S ribosomal protein L17 Mus musculus 278 90 1.58E-95 78.659 NP_001002239 Large subunit ribosomal protein L17e RPL17 structural constituent of ribosome translation large ribosomal subunit PF00237.21: Ribosomal_L22; PF00967.19: Barwin; - HyS0057.10 HyS0057.010 86 - - 4 yes - 2739.07 2656.84 2584.86 3260.95 641.333 974.855 1985.97 2081.37 2810.43 808.094 2033.67 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: translation elongation factor 2-like [Hydra vulgaris] 0 XP_002157788.1 Elongation factor 2 Caenorhabditis elegans 1363 100 0 76.174 NP_001369996 Translation elongation factor 2 EEF-2 GTPase activity translational elongation cytosol PF00009.29: GTP_EFTU; PF03764.20: EFG_IV; PF00679.26: EFG_C; PF14492.8: EFG_III; PF03144.27: GTP_EFTU_D2; PF01926.25: MMR_HSR1; PF16658.7: RF3_C; - HyS0057.41 HyS0057.041 87 - - 4 yes - 833.759 623.181 714.729 711.848 277.041 328.282 1073.67 1194 720.87925 302.6615 1133.835 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: cytochrome b-c1 complex subunit 7-like [Hydra vulgaris] 8.80E-30 XP_002160238.1 cytochrome b-c1 complex subunit 7 Mus musculus 112 91 3.56E-32 51.429 NP_080495 mTERF domain-containing protein 1 UQCRB ubiquinol-cytochrome-c reductase activity "mitochondrial electron transport, ubiquinol to cytochrome c" mitochondrial respiratory chain complex III PF02271.18: UCR_14kD; - HyS0067.29 HyS0067.029 88 - sex-linked-abnormal 4 yes - 34.7675 15.7651 23.3837 33.4859 44.2009 45.0821 1011.4 719.307 26.85055 44.6415 865.3535 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 sperm-associated antigen 8-like [Stylophora pistillata] 1.30E-41 XP_022781928.1 sperm-associated antigen 8 isoform 1 Homo sapiens 72.4 84 7.04E-14 33.136 NP_001034681 Sperm-associated antigen 8 SPAG8 microtubule binding positive regulation of transcription by RNA polymerase II nucleus - - HyS0007.354 HyS0007.354 89 - - 4 yes - 10.1863 6.90515 6.46552 5.516 19.544 24.6413 636.82 417.818 7.2682425 22.09265 527.319 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 cilia- and flagella-associated protein 53-like [Pocillopora damicornis] 1.00E-40 XP_027056582.1 cilia- and flagella-associated protein 53 Danio rerio 196 97 6.92E-55 33.4 NP_001038595 DNA polymerase kappa NA damaged DNA binding cilium movement cilium PF13868.8: TPH; - HyS0057.49 HyS0057.049 90 - - 4 yes - 28.8373 25.5896 27.4909 25.5754 22.201 22.1381 509.143 477.326 26.8733 22.16955 493.2345 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 IQ domain-containing protein H-like [Orbicella faveolata] 8.20E-245 XP_020625983.1 IQ domain-containing protein H isoform 1 Homo sapiens 679 72 0 41.646 NP_001026885 IQ domain-containing protein H IQCH NA NA NA PF00612.29: IQ; PF10860.10: DUF2661; - HyS4218.1 HyS4218.001 91 - sex-linked-abnormal - - - 1754.64 936.51 1111.99 1955.38 258.671 341.511 782.147 676.67 1439.63 300.091 729.4085 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 40S ribosomal protein S15 [Spizellomyces punctatus DAOM BR117] 9.50E-65 XP_016609073.1 40S ribosomal protein S15 Glycine max 231 83 8.50E-78 77.143 NP_001237868 "Ribosomal protein S15, eukaryotic/archaeal" RPS15 structural constituent of ribosome translation small ribosomal subunit PF00203.23: Ribosomal_S19; PF06952.13: PsiA; - HyS0057.17 HyS0057.017 92 - - 4 yes - 69.0217 66.0705 61.8421 74.1278 77.5996 71.4619 532.746 473.063 67.765525 74.53075 502.9045 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: E3 ubiquitin-protein ligase arih1-like [Hydra vulgaris] 1.60E-248 XP_002158303.2 E3 ubiquitin-protein ligase arih1 Danio rerio 645 99 0 61.373 NP_956052 RING-type E3 ubiquitin transferase ARIH1 ubiquitin-protein transferase activity protein ubiquitination Lewy body PF01485.23: IBR; PF19422.1: Ariadne; PF13445.8: zf-RING_UBOX; PF00097.27: zf-C3HC4; PF13639.8: zf-RING_2; PF13923.8: zf-C3HC4_2; PF14634.8: zf-RING_5; PF00373.20: FERM_M; PF11546.10: CompInhib_SCIN; PF17123.7: zf-RING_11; PF19498.1: DUF6033; - HyS0007.298 HyS0007.298 93 - - 4 yes - 242.206 180.608 237.418 202.855 167.856 173.158 513.392 405.407 215.77175 170.507 459.3995 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: cAMP-regulated phosphoprotein 19-like [Hydra vulgaris] 6.20E-26 XP_012563138.1 cAMP-regulated phosphoprotein 19 isoform 1 Mus musculus 70.5 61 1.25E-15 51.807 NP_001344807 Endosulfine alpha b ARPP19 protein phosphatase inhibitor activity negative regulation of phosphoprotein phosphatase activity cytoplasm PF04667.19: Endosulfine; - HyS0057.103 HyS0057.103 94 - - 4 yes - 232.079 230.562 254.007 348.393 151.381 180.217 479.309 383.274 266.26025 165.799 431.2915 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: ribosome biogenesis protein NSA2 homolog [Hydra vulgaris] 3.50E-135 XP_002157278.1 ribosome biogenesis protein NSA2 homolog Mus musculus 443 100 1.87E-158 81.154 NP_067527 TGF-beta-inducible nuclear protein 1 NSA2 RNA binding rRNA processing "preribosome, large subunit precursor" PF01201.24: Ribosomal_S8e; - HyS0067.31 HyS0067.031 95 - sex-linked-abnormal 4 yes - 465.372 378.322 346.531 573.33 211.444 248.137 526.86 401.231 440.88875 229.7905 464.0455 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: keratinocyte-associated protein 2-like [Hydra vulgaris] 4.50E-41 XP_002157231.2 keratinocyte-associated protein 2 Danio rerio 139 86 4.46E-42 59.483 NP_001038827 LOW QUALITY PROTEIN: keratinocyte-associated protein 2 KRTCAP2 dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein N-linked glycosylation via arginine oligosaccharyltransferase complex PF09775.11: Keratin_assoc; PF04511.17: DER1; PF07869.14: DUF1656; PF04247.14: SirB; PF16931.7: Phage_holin_8; - HyS0070.41 HyS0070.041 96 - sex-linked-abnormal - - - 697.91 672.21 810.9 1378.83 71.6753 116.856 332.745 318.977 889.9625 94.26565 325.861 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100200582 [Hydra vulgaris] 2.60E-53 XP_002154885.1 MULTISPECIES: NAD(P)H-dependent oxidoreductase Streptomyces 62.4 64 8.02E-11 32.576 WP_003976326 NA NA NA NA NA PF03358.17: FMN_red; PF02525.19: Flavodoxin_2; - HyS0007.265 HyS0007.265 97 - - 4 yes - 8.23936 3.99083 7.86139 4.42346 26.6677 23.2482 278.084 205.708 6.12876 24.95795 241.896 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: dynein intermediate chain 2, ciliary-like [Hydra vulgaris]" 1.10E-247 XP_012559387.1 dynein axonemal intermediate chain 1 Mus musculus 779 95 0 56.623 NP_780347 Dynein intermediate chain axonemal DNAI1 dynein light chain binding outer dynein arm assembly outer dynein arm PF00400.34: WD40; PF15907.7: Itfg2; - HyS0057.22 HyS0057.022 98 - - 4 yes - 148.432 118.679 102.656 154.869 80.8534 103.942 296.469 318.15 131.159 92.3977 307.3095 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6-like [Hydra vulgaris] 2.70E-40 XP_002161890.2 NADH dehydrogenase 1 alpha subcomplex subunit 6 Mus musculus 136 87 4.22E-41 58.559 NP_080263 LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 NA oxidation-reduction process mitochondrial inner membrane PF05347.17: Complex1_LYR; PF13233.8: Complex1_LYR_2; - HyS0067.32 HyS0067.032 99 - sex-linked-abnormal 4 yes - 19.1927 38.8062 39.3933 20.3206 52.5178 47.3901 303.665 203.922 29.4282 49.95395 253.7935 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: DET1- and DDB1-associated protein 1-like [Hydra vulgaris] 5.90E-14 XP_012560382.1 DET1- and DDB1-associated protein 1 Danio rerio 70.1 96 8.36E-16 42 NP_998292 Det1 complexing ubiquitin ligase DDA1 (1 OF MANY) ligase activity regulation of proteasomal ubiquitin-dependent protein catabolic process Cul4-RING E3 ubiquitin ligase complex PF10172.11: DDA1; PF04118.16: Dopey_N; PF11698.10: V-ATPase_H_C; - HyS0057.33 HyS0057.033 100 - - 4 yes - 28.446 28.5893 33.2418 33.0581 39.5479 36.2042 245.052 184.663 30.8338 37.87605 214.8575 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "ARNT, partial [Clytia hemisphaerica]" 4.90E-152 ALJ33572.1 aryl hydrocarbon receptor nuclear translocator isoform X15 Homo sapiens 432 61 1.04E-140 51.905 XP_016856785 Aryl hydrocarbon receptor nuclear translocator NA protein dimerization activity "regulation of transcription, DNA-templated" transcription factor complex PF08447.14: PAS_3; PF14598.8: PAS_11; PF00989.27: PAS; PF00010.28: HLH; PF13426.9: PAS_9; PF08448.12: PAS_4; - HyS0070.22 HyS0070.022 101 - sex-linked-abnormal - - - 8.11833 20.7035 14.125 11.0677 0.15911 0.90535 194.422 139.294 13.5036325 0.53223 166.858 1 0 1 0 1 0 0 0 0 1 0 1 0 1 0 0 0 0 PREDICTED: uncharacterized protein LOC107343194 [Acropora digitifera] 2.80E-50 XP_015764252.1 milk fat globule EGF and factor V/VIII domain containing a isoform 1 precursor Danio rerio 100 56 1.52E-21 31.469 NP_001014321 NA NA NA NA NA PF00754.27: F5_F8_type_C; - HyS0057.119 HyS0057.119 102 - - 4 yes - 175.973 106.494 139.848 207.588 82.6029 83.124 218.613 219.597 157.47575 82.86345 219.105 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-like [Hydra vulgaris] 5.90E-46 XP_002155069.1 NADH dehydrogenase 1 alpha subcomplex subunit 13 Danio rerio 131 92 6.43E-39 49.587 NP_957008 NADH-ubiquinone oxidoreductase subunit NDUFA13 NADH dehydrogenase (ubiquinone) activity vesicle-mediated transport integral component of membrane PF06212.14: GRIM-19; - HyS0007.403 HyS0007.403 103 - - 4 yes - 11.2734 13.579 12.9594 17.6353 15.1727 17.485 158.23 134.917 13.861775 16.32885 146.5735 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1 [Hydra vulgaris]" 8.60E-172 XP_002167314.2 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1 " Homo sapiens 599 82 0 60.694 XP_011519466 Caseinolytic mitochondrial matrix peptidase chaperone subunit b CLPX unfolded protein binding protein folding mitochondrial endopeptidase Clp complex PF07724.16: AAA_2; PF00004.31: AAA; PF10431.11: ClpB_D2-small; PF07728.16: AAA_5; PF00158.28: Sigma54_activat; PF01078.23: Mg_chelatase; PF12775.9: AAA_7; PF13401.8: AAA_22; PF05496.14: RuvB_N; PF13191.8: AAA_16; PF13173.8: AAA_14; PF01695.19: IstB_IS21; PF00437.22: T2SSE; PF01580.20: FtsK_SpoIIIE; PF05729.14: NACHT; PF14532.8: Sigma54_activ_2; PF02367.19: TsaE; PF06068.15: TIP49; PF00493.25: MCM; PF00005.29: ABC_tran; PF13555.8: AAA_29; PF01842.27: ACT; PF07726.13: AAA_3; - HyS0057.12 HyS0057.012 104 - - 4 yes - 592.68 769.751 686.154 661.877 120.245 204.261 259.786 319.997 677.6155 162.253 289.8915 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: isocitrate dehydrogenase [NADP]-like [Hydra vulgaris] 1.50E-213 XP_002163048.2 "isocitrate dehydrogenase , mitochondrial " Danio rerio 641 96 0 70.67 NP_955858 Motochondrial isocitrate dehydrogenase IDH2 isocitrate dehydrogenase (NADP+) activity isocitrate metabolic process mitochondrion PF00180.22: Iso_dh; - HyS0057.123 HyS0057.123 105 - - 4 yes - 264.97 287.696 329.044 284.804 240.949 239.265 348.615 367.149 291.6285 240.107 357.882 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - uncharacterized protein LOC100149345 Danio rerio 51.6 76 1.23E-09 57.407 NP_001166132 Small EDRK-rich factor 2 SERF2 NA protein destabilization cytosol PF04419.16: 4F5; - HyS0067.74 HyS0067.074 106 - sex-linked-abnormal 4 yes - 88.0507 65.0913 61.4052 77.6918 97.7095 97.3563 233.954 192.275 73.05975 97.5329 213.1145 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial-like [Hydra vulgaris]" 6.20E-48 XP_002157726.1 "NADH dehydrogenase iron-sulfur protein 4, mitochondrial isoform 1 precursor " Homo sapiens 157 93 3.15E-48 49.375 NP_002486 NADH-ubiquinone oxidoreductase 18 kDa subunit NDUFS4 "oxidoreductase activity, acting on NAD(P)H" positive regulation of fibroblast proliferation mitochondrial respiratory chain complex I PF04800.14: ETC_C1_NDUFA4; - HyS0057.34 HyS0057.034 107 - - 4 yes - 13.6847 24.5211 23.0997 22.0776 12.4505 14.4616 136.145 118.965 20.845775 13.45605 127.555 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 MIP18 family protein FAM96A-like [Stylophora pistillata] 1.10E-31 XP_022807106.1 cytosolic iron-sulfur assembly component 2A isoform 1 precursor Mus musculus 139 93 8.45E-42 55.556 NP_080911 Cytosolic iron-sulfur assembly component 2A CIAO2A NA protein maturation by [4Fe-4S] cluster transfer CIA complex PF01883.21: FeS_assembly_P; PF06837.13: Fijivirus_P9-2; - HyS0116.2 HyS0116.002 108 - sex-linked-abnormal 4 yes - 4.09775 6.86645 6.06094 4.03373 10.2185 7.609 101.815 82.8179 5.2647175 8.91375 92.31645 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: uncharacterized protein LOC100202602, partial [Hydra vulgaris]" 6.00E-09 XP_012562734.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.374 HyS0007.374 109 - - 4 yes - 33.5366 20.8526 22.7045 28.8168 21.8882 22.7903 104.698 87.9304 26.477625 22.33925 96.3142 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: betaine--homocysteine S-methyltransferase 1-like [Hydra vulgaris] 1.10E-175 XP_012556069.1 betaine--homocysteine S-methyltransferase 1 Mus musculus 584 99 0 70.18 NP_057877 Betaine--homocysteine S-methyltransferase BHMT betaine-homocysteine S-methyltransferase activity methionine biosynthetic process extracellular exosome PF02574.18: S-methyl_trans; PF12466.10: GDH_N; - HyS0116.16 HyS0116.016 110 - sex-linked-abnormal 4 yes - 17.0605 14.0873 20.1265 16.6949 7.57884 9.57958 72.8322 56.2186 16.9923 8.57921 64.5254 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.397 HyS0007.397 111 - - 4 yes - 60.0851 55.3398 66.4054 49.4801 81.522 76.6668 137.643 128.889 57.8276 79.0944 133.266 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: electron transfer flavoprotein subunit alpha, mitochondrial-like [Hydra vulgaris]" 4.00E-123 XP_002161508.3 "electron transfer flavoprotein subunit alpha, mitochondrial " Danio rerio 445 94 1.11E-156 69.841 NP_944591 Mitochondrial electron transfer flavoprotein subunit alpha ETFA flavin adenine dinucleotide binding regulation of fatty acid beta-oxidation mitochondrion PF01012.23: ETF; PF00766.21: ETF_alpha; - HyS0067.43 HyS0067.043 112 - sex-linked-abnormal 4 yes - 9.02919 5.08904 9.21601 7.66579 13.9135 14.2615 72.646 62.2212 7.7500075 14.0875 67.4336 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: E3 ubiquitin-protein ligase MARCH11-like [Hydra vulgaris] 5.20E-68 XP_002156095.1 E3 ubiquitin-protein ligase MARCHF8 isoform 2 Mus musculus 68.6 63 9.05E-13 30.935 NP_001289314 NA NA NA NA NA PF12906.9: RINGv; PF13639.8: zf-RING_2; PF11793.10: FANCL_C; PF05290.13: Baculo_IE-1; - HyS0057.19 HyS0057.019 113 - - 4 yes - 18.6423 14.8118 15.1122 17.9498 24.6937 24.3346 87.6771 63.2507 16.629025 24.51415 75.4639 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: probable ATP-dependent RNA helicase DDX46 [Hydra vulgaris] 0 XP_002161749.2 probable ATP-dependent RNA helicase DDX46 Danio rerio 966 69 0 54.118 NP_001019988 ATP-dependent RNA helicase NA helicase activity "mRNA splicing, via spliceosome" nucleus PF00270.31: DEAD; PF00271.33: Helicase_C; PF06153.13: CdAMP_rec; - HyS0057.122 HyS0057.122 114 - - 4 yes - 306.039 339.879 289.722 361.559 199.859 224.006 296.479 226.796 324.29975 211.9325 261.6375 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: receptor expression-enhancing protein 5-like [Hydra vulgaris] 1.70E-76 XP_012553647.1 receptor expression-enhancing protein 5 Homo sapiens 205 94 1.69E-66 52.688 NP_005660 Receptor expression-enhancing protein 6 NA protein binding embryonic retina morphogenesis in camera-type eye integral component of membrane PF03134.21: TB2_DP1_HVA22; PF02364.17: Glucan_synthase; PF02687.23: FtsX; PF03137.22: OATP; - HyS0067.16 HyS0067.016 115 - sex-linked-abnormal 4 yes - 11.0038 4.15833 2.90131 5.48521 16.1457 14.5769 69.3769 55.7847 5.8871625 15.3613 62.5808 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 leucine-rich repeat-containing protein 27-like isoform X2 [Dendronephthya gigantea] 3.60E-26 XP_028391122.1 leucine-rich repeat-containing protein 27 isoform a Mus musculus 115 87 1.45E-26 26.067 NP_081440 Leucine-rich repeat-containing protein 27 (Fragment) NA kinase activity phosphorylation integral component of membrane PF13855.8: LRR_8; PF12799.9: LRR_4; PF14580.8: LRR_9; PF00560.35: LRR_1; PF18426.3: Tli4_C; - HyS0057.98 HyS0057.098 116 - - 4 yes - 84.1656 86.7451 75.4921 76.9127 56.5124 54.2968 118.602 86.1376 80.828875 55.4046 102.3698 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - "tropomyosin 1, isoform N " Drosophila melanogaster 108 98 4.07E-27 31.673 NP_001163619 Tropomyosin alpha-1 chain NA actin filament binding actin filament organization actin filament PF00261.22: Tropomyosin; PF12718.9: Tropomyosin_1; PF01576.21: Myosin_tail_1; PF04871.15: Uso1_p115_C; PF19220.2: Crescentin; PF10498.11: IFT57; PF06009.14: Laminin_II; PF15619.8: Lebercilin; PF04513.14: Baculo_PEP_C; PF13851.8: GAS; PF13863.8: DUF4200; PF06818.17: Fez1; PF01519.18: DUF16; PF05377.13: FlaC_arch; PF12795.9: MscS_porin; PF06160.14: EzrA; PF10458.11: Val_tRNA-synt_C; PF08614.13: ATG16; PF06013.14: WXG100; PF13166.8: AAA_13; PF20155.1: TMP_3; PF09325.12: Vps5; PF08702.12: Fib_alpha; PF04356.14: DUF489; PF05622.14: HOOK; PF02601.17: Exonuc_VII_L; PF07889.14: DUF1664; PF05701.13: WEMBL; PF16326.7: ABC_tran_CTD; PF10779.11: XhlA; PF06791.15: TMP_2; PF03148.16: Tektin; PF05557.15: MAD; PF11932.10: DUF3450; PF16888.7: DUF5082; PF09728.11: Taxilin; PF02050.18: FliJ; PF07926.14: TPR_MLP1_2; PF10473.11: CENP-F_leu_zip; PF07888.13: CALCOCO1; PF03961.15: FapA; PF05266.16: DUF724; PF05064.15: Nsp1_C; PF05911.13: FPP; PF01544.20: CorA; PF06008.16: Laminin_I; PF08647.13: BRE1; PF12329.10: TMF_DNA_bd; PF05335.15: DUF745; PF11559.10: ADIP; PF07303.15: Occludin_ELL; PF14739.8: DUF4472; PF16516.7: CC2-LZ; PF15456.8: Uds1; PF00038.23: Filament; PF14915.8: CCDC144C; PF04108.14: ATG17_like; PF18041.3: MapZ_EC1; PF15905.7: HMMR_N; PF10174.11: Cast; PF04012.14: PspA_IM30; PF05531.14: NPV_P10; PF16043.7: DUF4795; PF04102.14: SlyX; PF10241.11: KxDL; PF05276.16: SH3BP5; PF08286.13: Spc24; PF14362.8: DUF4407; PF09769.11: ApoO; PF06103.13: DUF948; PF11236.10: DUF3037; PF18595.3: DHR10; PF00769.21: ERM; PF07160.14: SKA1; - HyS0007.306 HyS0007.306 117 - - 4 yes - 70.6265 53.4415 51.7639 50.6196 63.0873 65.2108 127.847 89.7889 56.612875 64.14905 108.81795 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: LOW QUALITY PROTEIN: asparagine--tRNA ligase, cytoplasmic-like [Hydra vulgaris]" 5.10E-264 XP_002161050.3 "asparagine--tRNA ligase, cytoplasmic " Danio rerio 795 99 0 66.786 XP_696748 Asparaginyl-tRNA synthetase NARS asparagine-tRNA ligase activity asparaginyl-tRNA aminoacylation cytosol PF00152.22: tRNA-synt_2; PF01336.27: tRNA_anti-codon; PF07602.13: DUF1565; - HyS0007.377 HyS0007.377 118 - - 4 yes - 79.6727 51.6399 71.4585 104.198 11.5026 16.9423 66.0995 45.3569 76.742275 14.22245 55.7282 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC105847004 [Hydra vulgaris] 4.80E-22 XP_012561707.1 no hits - - - - - - NA NA NA NA NA PF17261.4: DUF5327; - HyS0070.59 HyS0070.059 119 - sex-linked-abnormal - - - 64.0856 100.304 75.0403 89.9453 102.14 98.8916 147.167 136.477 82.3438 100.5158 141.822 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: casein kinase I isoform alpha isoform X2 [Hydra vulgaris] 1.90E-174 XP_002158334.2 casein kinase I isoform X4 Mus musculus 598 53 0 83.333 XP_030106505 Casein kinase 1 protein catalytic subunit NA protein serine/threonine kinase activity protein phosphorylation nucleus PF00965.19: TIMP; PF00069.27: Pkinase; PF07714.19: PK_Tyr_Ser-Thr; PF17667.3: Pkinase_fungal; PF03109.18: ABC1; PF01636.25: APH; - HyS0007.415 HyS0007.415 120 - - 4 yes - 83.9155 60.7784 58.9824 78.6995 91.5626 107.575 171.952 109.521 70.59395 99.5688 140.7365 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF00769.21: ERM; PF04728.15: LPP; - HyS0007.409 HyS0007.409 121 - - 4 yes - 78.8883 65.8671 73.8767 125.255 49.7673 45.2915 94.2674 82.1007 85.971775 47.5294 88.18405 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: serine/threonine-protein kinase RIO1-like [Hydra vulgaris] 2.80E-58 XP_012564707.1 transcription initiation factor IIA subunit 1 isoform 3 Homo sapiens 125 30 5.39E-32 59.091 NP_001265869 Transcription initiation factor IIA subunit GTF2A1 translation initiation factor activity transcription initiation from RNA polymerase II promoter transcription factor TFIIA complex PF03153.15: TFIIA; PF12888.9: Lipid_bd; PF00581.22: Rhodanese; - HyS0057.106 HyS0057.106 122 - - 4 yes - 16.2032 14.4343 15.3692 12.2005 25.8493 20.222 59.6646 60.0369 14.5518 23.03565 59.85075 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100198745 [Hydra vulgaris] 2.50E-176 XP_002164517.2 no hits - - - - - - NA NA NA NA NA PF11312.10: Methyltransf_34; - HyS0070.14 HyS0070.014 123 - sex-linked-abnormal - - - 12.3443 22.2849 25.0071 22.8063 37.7013 37.7009 82.6552 64.6004 20.61065 37.7011 73.6278 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100205151 [Hydra vulgaris] 2.80E-45 XP_012561309.1 hypothetical protein DDB_G0274661 Dictyostelium discoideum AX4 63.2 92 1.66E-11 28.571 XP_644129 NA NA NA NA NA PF08592.13: DUF1772; - HyS0007.292 HyS0007.292 124 - - 4 yes - 63.1958 32.8678 62.4434 125.922 72.0741 69.357 125.543 86.5995 71.10725 70.71555 106.07125 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: leucine-rich repeat-containing protein 61 isoform X1 [Pygocentrus nattereri] 1.80E-08 XP_017563840.1 leucine-rich repeat-containing protein 61 isoform X1 Danio rerio 117 69 9.77E-31 42.771 XP_005163151 "Isocitrate dehydrogenase [NAD] subunit, mitochondrial" NA isocitrate dehydrogenase (NAD+) activity tricarboxylic acid cycle mitochondrion PF12799.9: LRR_4; PF13855.8: LRR_8; PF14580.8: LRR_9; PF13516.8: LRR_6; PF00560.35: LRR_1; - HyS0070.82 HyS0070.082 125 - sex-linked-abnormal - - - 19.6923 31.0651 23.6392 25.6127 63.0129 56.1133 104.74 82.2847 25.002325 59.5631 93.51235 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: synaptobrevin homolog YKT6-like [Hydra vulgaris] 1.10E-69 XP_012554967.1 YKT6 v-SNARE Drosophila melanogaster 238 100 3.50E-79 56.061 NP_572423 Synaptobrevin protein YKT6 YKT6 SNAP receptor activity vesicle-mediated transport integral component of membrane PF00957.23: Synaptobrevin; PF13774.8: Longin; PF03173.15: CHB_HEX; - HyS0070.9 HyS0070.009 126 - sex-linked-abnormal - - - 26.3433 34.9907 33.534 26.2491 57.2883 47.2475 96.2548 75.7671 30.279275 52.2679 86.01095 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 importin subunit alpha-7 [Halyomorpha halys] 3.10E-82 XP_024217235.1 importin subunit alpha-7 Danio rerio 652 99 0 63.364 XP_001923921 Importin subunit alpha KPNA6 nuclear import signal receptor activity protein import into nucleus nucleus PF00514.25: Arm; PF01749.22: IBB; PF16186.7: Arm_3; PF13513.8: HEAT_EZ; PF02985.24: HEAT; PF13646.8: HEAT_2; PF01602.22: Adaptin_N; PF11698.10: V-ATPase_H_C; PF14668.8: RICTOR_V; PF08216.13: CTNNBL; PF03130.18: HEAT_PBS; PF10274.11: ParcG; PF08569.13: Mo25; PF10698.11: DUF2505; PF12726.9: SEN1_N; PF17150.6: CHASE6_C; - HyS0007.293 HyS0007.293 127 - - 4 yes - 41.7297 42.9347 43.7579 54.4614 46.9741 44.2385 78.516 77.5653 45.720925 45.6063 78.04065 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: uncharacterized protein LOC100205913, partial [Hydra vulgaris]" 8.40E-61 XP_012554310.1 ubiquitin-associated protein 2 isoform X2 Danio rerio 61.2 7 5.91E-08 42.105 XP_017208299 NA NA NA NA NA PF12478.10: DUF3697; PF06972.13: GIP1_N; - HyS0057.63 HyS0057.063 128 - - 4 yes - 16.8193 30.0481 14.4175 17.9437 31.2884 26.9625 63.327 54.9959 19.80715 29.12545 59.16145 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: secretory carrier-associated membrane protein 2-like [Hydra vulgaris] 1.10E-70 XP_002156703.3 secretory carrier-associated membrane protein 1 Danio rerio 238 96 5.14E-72 42.949 NP_991255 Secretory carrier-associated membrane protein (Fragment) NA "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" protein transport recycling endosome membrane PF04144.15: SCAMP; PF09278.13: MerR-DNA-bind; PF16515.7: HIP1_clath_bdg; PF00170.23: bZIP_1; PF08397.13: IMD; PF07374.13: DUF1492; PF12269.10: CpG_bind_C; PF13600.8: DUF4140; PF16326.7: ABC_tran_CTD; - HyS0007.363 HyS0007.363 129 - - 4 yes - 14.1428 21.5089 23.6424 23.088 10.1463 10.8497 38.3781 37.6852 20.595525 10.498 38.03165 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 semaphorin-2A-like isoform X2 [Pocillopora damicornis] 8.70E-52 XP_027040203.1 uncharacterized protein LOC563087 Danio rerio 167 84 1.32E-41 26.437 NP_001038473 NA NA NA NA NA PF01403.21: Sema; PF01437.27: PSI; PF07679.18: I-set; PF13927.8: Ig_3; PF00047.27: ig; PF07494.13: Reg_prop; PF17205.5: PSI_integrin; - HyS0007.356 HyS0007.356 130 - - 4 yes - 11.8545 3.75856 9.34225 11.0726 1.72797 1.7554 32.3572 22.9525 9.0069775 1.741685 27.65485 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 Coiled-coil domain-containing protein 122 [Exaiptasia pallida] 3.40E-06 KXJ11892.1 laminin subunit beta-4 precursor Danio rerio 42.4 67 0.005 22.772 NP_775383 NA NA NA NA NA PF08614.13: ATG16; PF06818.17: Fez1; PF01041.19: DegT_DnrJ_EryC1; PF07321.14: YscO; PF09787.11: Golgin_A5; PF04356.14: DUF489; PF17767.3: NAPRTase_N; - HyS0067.69 HyS0067.069 131 - sex-linked-abnormal 4 yes - 9.00376 7.85352 8.28428 5.27883 2.82134 3.31981 31.3409 26.5595 7.6050975 3.070575 28.9502 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 coiled-coil domain-containing protein 87-like isoform X1 [Exaiptasia pallida] 1.10E-122 XP_020897424.1 coiled-coil domain-containing protein 87 Mus musculus 188 90 5.37E-48 23.9 NP_997151 Coiled-coil domain-containing CCDC87 NA positive regulation of acrosome reaction NA PF03999.14: MAP65_ASE1; PF12687.9: DUF3801; - HyS0007.323 HyS0007.323 132 - - 4 yes - 270.138 176.587 212.015 259.235 172.613 190.921 216.657 198.299 229.49375 181.767 207.478 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: T-complex protein 1 subunit gamma-like [Hydra vulgaris] 6.00E-270 XP_002163432.1 T-complex protein 1 subunit gamma Danio rerio 801 99 0 69.573 NP_775357 T-complex protein 1 subunit gamma NA unfolded protein binding protein folding chaperonin-containing T-complex PF00118.26: Cpn60_TCP1; - HyS0057.117 HyS0057.117 133 - - 4 yes - 10.5079 11.3137 9.10591 9.33775 15.0982 12.785 36.9918 35.9566 10.066315 13.9416 36.4742 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: uncharacterized protein LOC101239527, partial [Hydra vulgaris]" 5.70E-18 XP_004210609.2 gastrula zinc finger protein XlCGF8.2DB-like Danio rerio 132 28 1.70E-32 37.5 XP_021331137 Zinc finger protein 91 (Fragment) NA nucleic acid binding NA NA PF00096.28: zf-C2H2; PF13894.8: zf-C2H2_4; PF13465.8: zf-H2C2_2; PF12874.9: zf-met; PF00385.26: Chromo; PF05605.14: zf-Di19; PF12171.10: zf-C2H2_jaz; PF01155.21: HypA; PF17032.7: zinc_ribbon_15; - HyS0007.296 HyS0007.296 134 - - 4 yes - 81.8627 143.97 126.131 254.862 3.22603 18.3505 23.2941 42.9525 151.706425 10.788265 33.1233 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: protein disulfide-isomerase A3-like isoform X2 [Hydra vulgaris] 1.10E-41 XP_012557436.1 "protein disulfide isomerase family A, member 8 precursor " Danio rerio 87 51 1.41E-18 42.5 NP_001003517 Thioredoxin domain-containing protein NA isomerase activity cell redox homeostasis cell PF00085.22: Thioredoxin; PF13098.8: Thioredoxin_2; PF13899.8: Thioredoxin_7; PF01667.19: Ribosomal_S27e; - HyS0070.20 HyS0070.020 135 - sex-linked-abnormal - - - 9.09758 10.7055 10.1252 9.54343 9.5824 8.57972 34.2796 28.1209 9.8679275 9.08106 31.20025 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: splicing factor, arginine/serine-rich 15-like [Hydra vulgaris]" 1.10E-70 XP_002163748.2 "uncharacterized protein Dmel_CG4266, isoform C " Drosophila melanogaster 195 10 6.59E-53 62.222 NP_001261119 "Splicing factor, arginine/serine-rich" NA RNA binding NA NA PF04818.15: CID; PF00076.24: RRM_1; PF07916.13: TraG_N; - HyS0057.14 HyS0057.014 136 - - 4 yes - 63.8435 34.5043 43.5196 44.4835 43.2466 48.6521 78.4615 57.0946 46.587725 45.94935 67.77805 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: SURP and G-patch domain-containing protein 1-like [Hydra vulgaris] 4.10E-75 XP_002158499.2 SURP and G-patch domain-containing protein 1 isoform X6 Danio rerio 247 76 2.46E-77 39.886 XP_017207993 SURP and G-patch domain-containing protein 1 SUGP1 RNA binding RNA processing nucleoplasm PF01585.25: G-patch; PF01805.22: Surp; PF12656.9: G-patch_2; - HyS0057.50 HyS0057.050 137 - - 4 yes - 10.7471 9.25796 10.8021 13.1132 16.779 17.615 39.8285 35.2463 10.98009 17.197 37.5374 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: DNA polymerase alpha catalytic subunit [Hydra vulgaris] 0 XP_012559494.1 DNA polymerase alpha catalytic subunit isoform 1 Homo sapiens 1208 99 0 46.807 NP_001317289 DNA polymerase alpha catalytic subunit POLA1 DNA-directed DNA polymerase activity DNA biosynthetic process nucleus PF00136.23: DNA_pol_B; PF03104.21: DNA_pol_B_exo1; PF08996.12: zf-DNA_Pol; PF12254.10: DNA_pol_alpha_N; - HyS0067.40 HyS0067.040 138 - sex-linked-abnormal 4 yes - 14.1408 10.845 8.02084 7.55173 6.47831 6.27943 28.6669 24.2448 10.1395925 6.37887 26.45585 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 sodium/calcium exchanger 2-like [Pocillopora damicornis] 1.00E-193 XP_027054517.1 "solute carrier family 8 (sodium/calcium exchanger), member 4b isoform X1 " Danio rerio 258 64 6.63E-71 34.122 XP_005166593 Sodium/calcium exchanger NA calcium:sodium antiporter activity sodium ion transmembrane transport integral component of membrane PF01699.26: Na_Ca_ex; PF03160.16: Calx-beta; PF07332.13: Phage_holin_3_6; - HyS0007.376 HyS0007.376 139 - - 4 yes - 75.2031 55.961 59.8694 47.2087 24.8173 33.3733 52.4643 45.8355 59.56055 29.0953 49.1499 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 galactose-1-phosphate uridylyltransferase [Astyanax mexicanus] 4.30E-122 XP_007260878.1 galactose-1-phosphate uridylyltransferase Danio rerio 429 97 3.74E-150 62.069 NP_001315309 Galactose-1-phosphate uridylyltransferase GALT UDP-glucose:hexose-1-phosphate uridylyltransferase activity galactose catabolic process via UDP-galactose Golgi apparatus PF02744.19: GalP_UDP_tr_C; PF01087.24: GalP_UDP_transf; PF16285.7: DUF4931; PF01230.25: HIT; - HyS0070.15 HyS0070.015 140 - sex-linked-abnormal - - - 81.851 111.667 123.663 123.352 313.616 264.69 357.026 260.859 110.13325 289.153 308.9425 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: akirin-2-like [Hydra vulgaris] 4.40E-45 XP_002166734.2 akirin-1 isoform 2 Danio rerio 119 100 7.17E-33 38.756 NP_001007187 Akirin AKIRIN1 cannabinoid receptor activity cannabinoid signaling pathway integral component of membrane PF00505.21: HMG_box; - HyS0070.69 HyS0070.069 141 - sex-linked-abnormal - - - 769.224 436.575 544.238 550.983 20.9173 38.9983 44.705 53.2732 575.255 29.9578 48.9891 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: gelsolin-like protein 1 [Hydra vulgaris] 4.50E-157 XP_012559373.1 hypothetical protein DDB_G0289327 Dictyostelium discoideum AX4 261 93 7.10E-84 42.899 XP_001134515 Gelsolin NA actin filament binding actin filament severing cytoskeleton PF00626.24: Gelsolin; - HyS0070.8 HyS0070.008 142 - sex-linked-abnormal - - - 7.78285 8.26648 9.96224 4.6319 13.1629 10.9888 30.0974 26.1359 7.6608675 12.07585 28.11665 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: transient receptor potential cation channel subfamily A member 1-like [Hydra vulgaris] 1.50E-126 XP_012557933.1 transient receptor potential cation channel subfamily A member 1 isoform 1 Mus musculus 416 95 1.71E-125 30.237 NP_808449 Transient receptor potential cation channel subfamily A member 1 NA ion channel activity ion transmembrane transport integral component of membrane PF12796.9: Ank_2; PF13637.8: Ank_4; PF00023.32: Ank; PF13606.8: Ank_3; PF13857.8: Ank_5; PF00520.33: Ion_trans; PF18418.3: AnkUBD; - HyS0070.39 HyS0070.039 143 - sex-linked-abnormal - - - 18.8673 26.3247 24.9714 21.3751 23.0045 21.5134 40.3744 35.7859 22.884625 22.25895 38.08015 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: LOW QUALITY PROTEIN: syntaxin-binding protein 5-like [Saccoglossus kowalevskii] 1.10E-204 XP_006823584.1 syntaxin-binding protein 5a Danio rerio 701 100 0 37.009 NP_001093451 syntaxin-binding protein 5 STXBP5L myosin II binding vesicle-mediated transport integral component of membrane PF08366.15: LLGL; PF08596.12: Lgl_C; PF00957.23: Synaptobrevin; PF00400.34: WD40; PF12894.9: ANAPC4_WD40; PF11715.10: Nup160; PF07628.13: DUF1589; - HyS0067.28 HyS0067.028 144 - sex-linked-abnormal 4 yes - 73.1979 92.0274 101.507 97.8781 98.09 95.3148 123.819 97.8112 91.1526 96.7024 110.8151 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: alpha/beta hydrolase domain-containing protein 17B-like [Hydra vulgaris] 2.40E-161 XP_002162084.1 alpha/beta hydrolase domain-containing protein 17C Danio rerio 477 99 1.12E-170 74.296 NP_956451 Alpha/beta hydrolase domain-containing protein 17C NA hydrolase activity macromolecule depalmitoylation recycling endosome membrane PF12146.10: Hydrolase_4; PF00561.22: Abhydrolase_1; PF12697.9: Abhydrolase_6; PF00326.23: Peptidase_S9; PF05677.14: DUF818; PF01738.20: DLH; PF02230.18: Abhydrolase_2; PF05728.14: UPF0227; PF12695.9: Abhydrolase_5; PF16929.7: Asp2; PF03959.15: FSH1; - HyS0057.27 HyS0057.027 145 - - 4 yes - 23.8622 24.0094 23.4811 21.6891 3.23261 5.80086 20.4137 16.7255 23.26045 4.516735 18.5696 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 PREDICTED: probable Xaa-Pro aminopeptidase P [Hydra vulgaris] 8.40E-213 XP_012555787.1 xaa-Pro aminopeptidase 1 isoform X1 Danio rerio 544 90 0 43.71 XP_021324983 Xaa-Pro aminopeptidase AMPP metalloaminopeptidase activity proteolysis exocyst PF16189.7: Creatinase_N_2; PF00557.26: Peptidase_M24; PF01321.20: Creatinase_N; PF16188.7: Peptidase_M24_C; - HyS0113.39 HyS0113.039 146 - sex-linked-abnormal 4 yes - 84.2374 54.6989 59.7336 92.369 82.6137 79.5144 108.859 80.7394 72.759725 81.06405 94.7992 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: HAUS augmin-like complex subunit 1 [Hydra vulgaris] 1.80E-42 XP_002164569.2 HAUS augmin-like complex subunit Arabidopsis thaliana 117 87 1.24E-29 29.885 NP_565949 NA NA NA NA NA PF18397.3: IKBKB_SDD; PF10585.11: UBA_e1_thiolCys; PF10199.11: Adaptin_binding; PF00664.25: ABC_membrane; - HyS0620.1 HyS0620.001 147 - sex-linked-abnormal 4 yes - 29.844 17.7034 14.1607 19.6296 3.85394 7.29958 19.421 18.4451 20.334425 5.57676 18.93305 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 S15 [Suberites domuncula] 3.40E-42 AAX48891.1 40S ribosomal protein S15 Glycine max 160 90 1.16E-50 72.816 NP_001237868 "Ribosomal protein S15, eukaryotic/archaeal" RPS15 structural constituent of ribosome translation small ribosomal subunit PF00203.23: Ribosomal_S19; PF06952.13: PsiA; - HyS0007.344 HyS0007.344 148 - - 4 yes - 706.94 395.322 252.955 413.823 11.1531 18.4029 35.1814 19.9008 442.26 14.778 27.5411 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - CRiM (Cysteine Rich motor neuron protein) homolog Caenorhabditis elegans 44.3 38 7.70E-05 44.898 NP_741618 NA NA NA NA NA PF02822.16: Antistasin; - HyS0057.96 HyS0057.096 149 - - 4 yes - 6.33826 8.79106 9.76366 4.71968 12.5777 9.25004 24.9015 21.6534 7.403165 10.91387 23.27745 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: protein dispatched homolog 1-like [Hydra vulgaris] 1.10E-235 XP_012567028.1 protein dispatched homolog 1 isoform X2 Homo sapiens 508 91 3.89E-159 33.467 XP_006711657 SSD domain-containing protein NA calcium ion binding smoothened signaling pathway integral component of membrane PF02460.20: Patched; PF12349.10: Sterol-sensing; PF03176.17: MMPL; - HyS0057.120 HyS0057.120 150 - - 4 yes - 24.597 21.0413 23.571 33.5657 20.3538 24.9737 36.626 33.076 25.69375 22.66375 34.851 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 FK506-binding protein 4-like [Exaiptasia pallida] 3.90E-28 XP_020907840.1 FKBP-like peptidyl-prolyl cis-trans isomerase family protein Arabidopsis thaliana 70.9 34 1.53E-12 37.895 NP_187840 NA NA NA NA NA PF17800.3: NPL; PF03066.17: Nucleoplasmin; - HyS0070.45 HyS0070.045 151 - sex-linked-abnormal - - - 19.5243 12.013 25.6038 19.401 44.385 40.8008 57.6072 50.9046 19.135525 42.5929 54.2559 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100212533 [Hydra vulgaris] 1.30E-05 XP_002156844.3 no hits - - - - - - NA NA NA NA NA - - HyS0007.380 HyS0007.380 152 - - 4 yes - 23.413 13.2232 18.8689 21.0373 15.0165 13.0088 30.7448 20.5686 19.1356 14.01265 25.6567 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: 5'-nucleotidase domain-containing protein 3-like [Hydra vulgaris] 5.10E-173 XP_012556807.1 5'-nucleotidase domain-containing protein 2 isoform 1 Homo sapiens 425 94 1.74E-142 43.922 NP_001127703 5'-nucleotidase domain-containing protein 2 NT5DC2 metal ion binding dephosphorylation NA PF05761.16: 5_nucleotid; PF19909.1: DUF6382; PF13419.8: HAD_2; PF19776.1: DUF6262; - HyS0116.1 HyS0116.001 153 - sex-linked-abnormal 4 yes - 161.904 124.856 123.177 225.421 121.297 119.964 147.914 116.572 158.8395 120.6305 132.243 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: LIM and senescent cell antigen-like-containing domain protein 1 [Hydra vulgaris] 1.20E-188 XP_002164622.2 LIM and senescent cell antigen-like-containing domain protein 1 isoform l Homo sapiens 414 97 1.95E-144 61.755 NP_001381825 LIM zinc finger domain containing 2 LIMS2 metal ion binding positive regulation of integrin-mediated signaling pathway focal adhesion PF00412.24: LIM; - HyS0113.29 HyS0113.029 154 - sex-linked-abnormal 4 yes - 16.9898 13.6284 17.4647 29.5372 16.6674 19.2836 33.9588 25.2062 19.405025 17.9755 29.5825 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - uncharacterized protein Dmel_CG42557 Drosophila melanogaster 45.1 48 1.37E-04 30.719 NP_651751 NA NA NA NA NA PF14989.8: CCDC32; PF20003.1: fvmX5; PF08357.13: SEFIR; PF14981.8: FAM165; - HyS0007.379 HyS0007.379 155 - - 4 yes - 24.2143 29.2499 26.3704 39.8734 48.7108 50.2377 67.579 54.1074 29.927 49.47425 60.8432 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: COP9 signalosome complex subunit 2-like [Hydra vulgaris] 4.60E-212 XP_012555414.1 COP9 signalosome complex subunit 2 isoform 1 Homo sapiens 726 100 0 79.684 NP_004227 COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) COPS2 transcription corepressor activity protein deneddylation COP9 signalosome PF01399.29: PCI; PF13176.8: TPR_7; PF14638.8: FNIP_C; PF13682.8: CZB; - HyS0007.312 HyS0007.312 156 - - 4 yes - 18.5832 23.4182 22.8869 30.1581 9.25794 10.2362 19.0835 23.0852 23.7616 9.74707 21.08435 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: zinc finger RNA-binding protein-like [Hydra vulgaris] 1.10E-244 XP_002153846.1 "Zinc-finger protein at 72D, isoform F " Drosophila melanogaster 508 88 1.98E-162 39.167 NP_001261924 Zinc finger RNA-binding protein 2 ZFR zinc ion binding peptidyl-tyrosine phosphorylation nucleus PF07528.16: DZF; PF12874.9: zf-met; PF12171.10: zf-C2H2_jaz; PF11931.10: SF3a60_Prp9_C; PF14845.8: Glycohydro_20b2; PF12756.9: zf-C2H2_2; PF13894.8: zf-C2H2_4; PF19088.2: TUTase; - HyS0057.107 HyS0057.107 157 - - 4 yes - 17.7888 21.1517 20.0541 14.7449 9.98221 9.744 18.6616 23.6888 18.434875 9.863105 21.1752 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: ras-specific guanine nucleotide-releasing factor 2-like [Hydra vulgaris] 1.80E-140 XP_012566721.1 ras-specific guanine nucleotide-releasing factor 2-like isoform X1 Danio rerio 276 59 1.38E-74 33.712 XP_009303357 Ras guanine nucleotide exchange factor RASGRF1 guanyl-nucleotide exchange factor activity small GTPase mediated signal transduction NA PF00617.21: RasGEF; PF00621.22: RhoGEF; PF00618.22: RasGEF_N; - HyS0007.366 HyS0007.366 158 - - 4 yes - 32.3879 34.2867 37.3351 59.3474 1.79852 7.5513 11.4906 20.1544 40.839275 4.67491 15.8225 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 MAM and LDL-receptor class A domain-containing protein 1-like isoform X2 [Orbicella faveolata] 5.60E-100 XP_020624544.1 MAM and LDL-receptor class A domain-containing protein 1 Danio rerio 210 35 1.37E-53 38.56 XP_021323714 MAM and LDL-receptor class A domain-containing protein 2 NA metalloendopeptidase activity proteolysis extracellular region PF00629.25: MAM; PF01400.26: Astacin; PF15711.7: ILEI; PF00090.21: TSP_1; PF19028.2: TSP1_spondin; PF19030.2: TSP1_ADAMTS; PF11921.10: DUF3439; - HyS0007.400 HyS0007.400 159 - - 4 yes - 12.8611 14.2229 11.0545 7.74047 24.4353 20.4668 29.1075 35.8777 11.4697425 22.45105 32.4926 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: protein AF-9-like [Hydra vulgaris] 3.40E-60 XP_002165177.2 protein AF-9 isoform X3 Mus musculus 194 25 3.56E-55 61.94 XP_036020304 Myeloid/lymphoid or mixed lineage-leukemia translocation to 3 homolog MLLT3 lysine-acetylated histone binding "regulation of transcription, DNA-templated" nucleus PF03366.18: YEATS; PF17793.3: AHD; PF17035.7: BET; PF10149.11: TM231; - HyS0007.317 HyS0007.317 160 - - 4 yes - 15.5048 20.3525 13.5747 12.617 24.5105 26.6354 36.3704 34.3874 15.51225 25.57295 35.3789 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: tetratricopeptide repeat protein 39C-like [Hydra vulgaris] 6.20E-196 XP_002167925.3 tetratricopeptide repeat protein 39C isoform 1 Homo sapiens 426 96 9.17E-142 39.965 NP_001129465 Tetratricopeptide repeat protein 39C TTC39C NA otolith morphogenesis NA PF10300.11: DUF3808; PF13424.8: TPR_12; PF07721.16: TPR_4; PF12895.9: ANAPC3; PF14559.8: TPR_19; PF13174.8: TPR_6; PF07719.19: TPR_2; PF00515.30: TPR_1; PF13432.8: TPR_16; PF13176.8: TPR_7; PF10345.11: Cohesin_load; PF13181.8: TPR_8; - HyS0007.302 HyS0007.302 161 - - 4 yes - 2.59375 7.78578 6.01755 7.84082 6.04933 6.08863 18.2567 13.1312 6.059475 6.06898 15.69395 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: kelch-like protein 2 [Hydra vulgaris] 7.50E-167 XP_012555886.1 kelch-like protein 20 Mus musculus 299 97 1.05E-92 32.911 NP_001034571 BTB domain-containing protein NA DNA binding NA nucleus PF01344.27: Kelch_1; PF13964.8: Kelch_6; PF07707.17: BACK; PF00651.33: BTB; PF07646.17: Kelch_2; PF13415.8: Kelch_3; PF13418.8: Kelch_4; PF13854.8: Kelch_5; PF19755.1: DUF6242; - HyS0057.26 HyS0057.026 162 - - 4 yes - 64.037 47.3118 41.8441 24.896 26.4238 32.6376 47.208 31.0991 44.522225 29.5307 39.15355 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100207912 [Hydra vulgaris] 1.50E-97 XP_002167814.3 peptidyl-prolyl cis-trans isomerase FKBP8 Danio rerio 222 46 6.73E-65 41.391 NP_957178 Peptidylprolyl isomerase FKBP8 peptidyl-prolyl cis-trans isomerase activity protein peptidyl-prolyl isomerization integral component of endoplasmic reticulum membrane PF07719.19: TPR_2; PF00254.30: FKBP_C; PF13414.8: TPR_11; PF00515.30: TPR_1; PF13181.8: TPR_8; PF14559.8: TPR_19; PF13428.8: TPR_14; PF13431.8: TPR_17; PF14853.8: Fis1_TPR_C; PF13432.8: TPR_16; PF02389.17: Cornifin; PF13174.8: TPR_6; - HyS0120.21 HyS0120.021 163 - sex-linked-abnormal 4 yes - 7.43903 2.66055 1.78943 44.8298 0.41309 0.195887 7.57944 11.8331 14.1797025 0.3044885 9.70627 1 0 1 0 1 0 0 0 0 1 0 1 0 1 0 0 0 0 no hits - - E3 ubiquitin-protein ligase TRIM17 Mus musculus 42.4 24 0.01 26.357 NP_112449 NA NA NA NA NA PF00643.26: zf-B_box; PF19071.2: DUF5767; PF17279.4: DUF5344; PF05400.15: FliT; - HyS0069.31 HyS0069.031 164 - sex-linked-abnormal - - - 26.3569 26.6317 26.2858 40.4005 2.92647 3.23539 10.1567 14.7542 29.918725 3.08093 12.45545 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF08074.13: CHDCT2; - HyS0007.318 HyS0007.318 165 - - 4 yes - 6.83548 7.85025 5.2076 8.0348 4.11207 4.13998 15.6659 11.2155 6.9820325 4.126025 13.4407 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 E3 ubiquitin-protein ligase TRIM33-like [Dendronephthya gigantea] 2.90E-16 XP_028392236.1 E3 ubiquitin-protein ligase Midline-1 isoform 4 Homo sapiens 70.5 66 1.31E-11 25.326 NP_001180208 NA NA NA NA NA PF13445.8: zf-RING_UBOX; PF13920.8: zf-C3HC4_3; PF00097.27: zf-C3HC4; PF13923.8: zf-C3HC4_2; PF14634.8: zf-RING_5; PF13639.8: zf-RING_2; PF15227.8: zf-C3HC4_4; PF14447.8: Prok-RING_4; PF16566.7: CREPT; PF14835.8: zf-RING_6; PF00643.26: zf-B_box; PF01548.19: DEDD_Tnp_IS110; PF13470.8: PIN_3; PF10256.11: Erf4; PF10372.11: YojJ; PF11559.10: ADIP; - HyS0070.58 HyS0070.058 166 - sex-linked-abnormal - - - 232.599 324.588 301.912 270.745 12.3862 48.2292 50.0977 29.0073 282.461 30.3077 39.5525 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0067.45 HyS0067.045 167 - sex-linked-abnormal 4 yes - 15.5861 17.0726 14.9326 20.479 13.6317 18.4706 25.2289 24.84 17.017575 16.05115 25.03445 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: protein FAM172A-like [Hydra vulgaris] 9.00E-84 XP_004212439.2 cotranscriptional regulator FAM172A isoform 2 Homo sapiens 225 44 1.68E-66 38.576 NP_001156889 GPI inositol-deacylase NA siRNA binding chromatin silencing by small RNA endoplasmic reticulum membrane PF09757.11: Arb2; PF12697.9: Abhydrolase_6; PF05057.16: DUF676; - HyS0007.333 HyS0007.333 168 - - 4 yes - 42.0836 39.3216 39.0478 55.7813 53.3747 45.6505 61.3351 55.6536 44.058575 49.5126 58.49435 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: maspardin-like [Hydra vulgaris] 3.90E-150 XP_012559096.1 maspardin isoform a Homo sapiens 413 88 1.93E-144 60.87 NP_001121361 "Spastic paraplegia 21, maspardin (Autosomal recessive, Mast syndrome)" SPG21 CD4 receptor binding vesicle-mediated transport trans-Golgi network transport vesicle PF00561.22: Abhydrolase_1; PF12697.9: Abhydrolase_6; PF12146.10: Hydrolase_4; PF12695.9: Abhydrolase_5; PF04195.14: Transposase_28; PF03096.16: Ndr; PF07859.15: Abhydrolase_3; - HyS0057.115 HyS0057.115 169 - - 4 yes - 32.3248 32.7247 36.1445 33.2213 30.4485 29.0037 37.7335 38.8998 33.603825 29.7261 38.31665 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 homer protein homolog 2-like isoform X1 [Pocillopora damicornis] 7.80E-48 XP_027044805.1 homer protein homolog 2 isoform 2 Homo sapiens 261 79 1.45E-83 49.141 NP_955362 homer protein homolog 3 NA G protein-coupled glutamate receptor binding G protein-coupled glutamate receptor signaling pathway postsynaptic density PF00568.25: WH1; PF05911.13: FPP; PF10267.11: Tmemb_cc2; PF13851.8: GAS; PF14362.8: DUF4407; - HyS0057.74 HyS0057.074 170 - - 4 yes - 43.4068 35.3831 40.3094 59.4311 48.8059 35.2174 55.9869 45.1973 44.6326 42.01165 50.5921 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: microsomal glutathione S-transferase 2-like [Hydra vulgaris] 1.70E-41 XP_002154468.2 microsomal glutathione S-transferase 2 isoform 1 Mus musculus 121 79 9.55E-35 50.427 NP_778160 Glutathione S-transferase theta MGST2 enzyme activator activity leukotriene metabolic process intracellular membrane-bounded organelle PF01124.20: MAPEG; - HyS0113.30 HyS0113.030 171 - sex-linked-abnormal 4 yes - 33.1918 22.5826 41.5809 26.9435 3.97064 6.64013 13.8864 13.6171 31.0747 5.305385 13.75175 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 cartilage oligomeric matrix protein-like isoform X4 [Orbicella faveolata] 4.00E-78 XP_020631889.1 thrombospondin-3b isoform X1 Danio rerio 603 94 0 38.125 XP_005170119 Cartilage oligomeric matrix protein variant (Fragment) COMP calcium ion binding cell adhesion extracellular region PF05735.14: TSP_C; PF02412.20: TSP_3; PF07645.17: EGF_CA; PF12947.9: EGF_3; PF12662.9: cEGF; PF00008.29: EGF; - HyS0070.62 HyS0070.062 172 - sex-linked-abnormal - - - 13.1863 22.6939 21.991 11.5991 8.42068 8.15888 17.8107 15.6221 17.367575 8.28978 16.7164 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2-like [Hydra vulgaris]" 1.30E-104 XP_002163521.1 "protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 precursor " Mus musculus 296 97 6.93E-94 39.851 NP_001276487 Glycosyltransferase POMGNT2 protein O-GlcNAc transferase activity protein O-linked mannosylation endoplasmic reticulum PF04577.16: Glyco_transf_61; - HyS0070.66 HyS0070.066 173 - sex-linked-abnormal - - - 12.7955 10.9365 13.75 9.53428 13.3294 11.8507 22.5112 19.3977 11.75407 12.59005 20.95445 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: PAB-dependent poly(A)-specific ribonuclease subunit PAN2-like [Hydra vulgaris] 0 XP_012558675.1 PAN2-PAN3 deadenylation complex catalytic subunit Pan2 isoform 2 Mus musculus 975 97 0 44.501 NP_001239255 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 poly(A)-specific ribonuclease activity positive regulation of cytoplasmic mRNA processing body assembly PAN complex PF13423.8: UCH_1; PF00929.26: RNase_T; PF00443.31: UCH; - HyS0113.41 HyS0113.041 174 - sex-linked-abnormal 4 yes - 13.7476 9.21262 11.3101 21.6199 6.0185 8.28471 14.0067 16.6984 13.972555 7.151605 15.35255 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: UPF0469 protein KIAA0907-like [Hydra vulgaris] 1.70E-80 XP_012562301.1 UPF0469 protein KIAA0907 homolog isoform X7 Danio rerio 138 34 9.42E-34 33.466 XP_009291025 "KH domain containing 4, pre-mRNA splicing factor" NA RNA binding NA nucleus PF09650.12: PHA_gran_rgn; - HyS0070.73 HyS0070.073 175 - sex-linked-abnormal - - - 6.92752 9.18217 8.2171 7.5183 11.7149 11.2781 20.5536 18.4662 7.9612725 11.4965 19.5099 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100208776 [Hydra vulgaris] 0 XP_012554809.1 E3 ubiquitin-protein ligase RNF123 isoform 2 Mus musculus 110 11 6.57E-23 38.037 NP_115932 RING finger and SPRY domain-containing protein 1-like NA ubiquitin-protein transferase activity protein ubiquitination cytoplasm PF00622.30: SPRY; PF00514.25: Arm; PF07177.14: Neuralized; - HyS0057.68 HyS0057.068 176 - - 4 yes - 60.8609 46.2932 53.6255 58.0237 26.4383 29.392 36.1342 35.1828 54.700825 27.91515 35.6585 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 peptidyl-glycine alpha-amidating monooxygenase B-like isoform X1 [Pomacea canaliculata] 2.70E-19 XP_025077134.1 peptidyl-glycine alpha-amidating monooxygenase isoform X10 Mus musculus 90.1 60 1.46E-19 39.259 XP_030108045 NA NA NA NA NA PF01436.23: NHL; PF08450.14: SGL; PF10282.11: Lactonase; PF17170.6: DUF5128; - HyS0070.80 HyS0070.080 177 - sex-linked-abnormal - - - 39.8222 35.844 36.0847 48.4583 49.1502 47.4115 54.1149 57.4707 40.0523 48.28085 55.7928 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: MICOS complex subunit MIC60-like isoform X1 [Hydra vulgaris] 1.30E-87 XP_012557738.1 MICOS complex subunit MIC60 Danio rerio 188 95 5.21E-49 25.726 NP_001001401 MICOS complex subunit MIC60 NA NA NA mitochondrial inner membrane PF09731.11: Mitofilin; - HyS0057.28 HyS0057.028 178 - - 4 yes - 24.1638 26.1129 32.1659 21.8655 17.2706 17.6756 27.2584 22.592 26.077025 17.4731 24.9252 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: non-lysosomal glucosylceramidase-like [Hydra vulgaris] 0 XP_002159451.3 non-lysosomal glucosylceramidase Danio rerio 634 90 0 53.177 XP_005172389 Non-lysosomal glucosylceramidase GBA2 glucosylceramidase activity glucosylceramide catabolic process extrinsic component of Golgi membrane PF04685.15: DUF608; PF12215.10: Glyco_hydr_116N; PF17389.4: Bac_rhamnosid6H; PF06202.16: GDE_C; PF17168.6: DUF5127; - HyS0057.62 HyS0057.062 179 - - 4 yes - 60.0134 64.3966 73.6703 81.0313 6.66503 19.4264 12.5597 27.5092 69.7779 13.045715 20.03445 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: transcription factor HES-2-like [Hydra vulgaris] 8.10E-30 XP_004208005.1 hairy-related 6 Danio rerio 108 96 2.11E-27 31.008 NP_571154 Transcription factor HES-4-A NA protein dimerization activity "regulation of transcription, DNA-templated" nucleus PF00010.28: HLH; PF07527.15: Hairy_orange; - HyS0067.12 HyS0067.012 180 - sex-linked-abnormal 4 yes - 5.45172 2.77598 4.86567 13.5836 3.55029 3.13301 12.1341 8.37012 6.6692425 3.34165 10.25211 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 PREDICTED: uncharacterized protein LOC100211324 [Hydra vulgaris] 1.30E-154 XP_012559251.1 hemicentin-1 isoform X2 Mus musculus 147 14 1.17E-33 28.406 XP_006529821 Hemicentin NA semaphorin receptor binding negative regulation of angiogenesis integral component of membrane PF00041.23: fn3; PF00090.21: TSP_1; PF19028.2: TSP1_spondin; PF07885.18: Ion_trans_2; PF19035.2: TSP1_CCN; PF19030.2: TSP1_ADAMTS; PF16893.7: fn3_2; - HyS0007.373 HyS0007.373 181 - - 4 yes - 43.0935 38.5493 55.3974 40.7732 24.2152 27.3442 34.0509 31.2623 44.45335 25.7797 32.6566 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: dimethylglycine dehydrogenase, mitochondrial-like [Hydra vulgaris]" 0 XP_012556067.1 "dimethylglycine dehydrogenase, mitochondrial precursor " Mus musculus 1020 94 0 57.46 NP_083048 Dimethylglycine mitochondrial DMGDH dimethylglycine dehydrogenase activity choline catabolic process mitochondrion PF01571.23: GCV_T; PF01266.26: DAO; PF08669.13: GCV_T_C; PF16350.7: FAO_M; PF13738.8: Pyr_redox_3; PF13450.8: NAD_binding_8; PF01494.21: FAD_binding_3; PF07992.16: Pyr_redox_2; PF00890.26: FAD_binding_2; PF13454.8: NAD_binding_9; PF02558.18: ApbA; PF01946.19: Thi4; PF02737.20: 3HCDH_N; PF03486.16: HI0933_like; PF04268.14: SoxG; PF00070.29: Pyr_redox; PF05834.14: Lycopene_cycl; PF01488.22: Shikimate_DH; PF03807.19: F420_oxidored; - HyS0067.19 HyS0067.019 182 - sex-linked-abnormal 4 yes - 6.17361 6.48563 7.19291 6.13108 6.50259 6.10517 14.0144 11.567 6.4958075 6.30388 12.7907 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: ubiquitin-like modifier-activating enzyme 6 [Hydra vulgaris] 0.00E+00 XP_012562691.1 ubiquitin-like modifier-activating enzyme 6 Homo sapiens 1058 99 0 51.66 NP_060697 Ubiquitin like modifier activating enzyme 6 UBA6 ubiquitin-like modifier activating enzyme activity amygdala development nucleus PF00899.23: ThiF; PF10585.11: UBA_e1_thiolCys; PF16190.7: E1_FCCH; PF09358.12: E1_UFD; PF16191.7: E1_4HB; PF02826.21: 2-Hacid_dh_C; PF01488.22: Shikimate_DH; PF07992.16: Pyr_redox_2; PF00070.29: Pyr_redox; PF02254.20: TrkA_N; - HyS0069.13 HyS0069.013 183 - sex-linked-abnormal - - - 11.5134 10.5935 9.38044 28.0835 0.657608 1.50731 5.55781 9.56228 14.89271 1.082459 7.560045 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 uncharacterized protein LOC114526667 [Dendronephthya gigantea] 1.80E-26 XP_028404045.1 E3 ubiquitin-protein ligase TRIM17 Mus musculus 43.5 19 0.007 27.132 NP_112449 NA NA NA NA NA PF00643.26: zf-B_box; PF19071.2: DUF5767; PF18498.3: DUF5618; PF17279.4: DUF5344; - HyS0007.362 HyS0007.362 184 - - 4 yes - 13.9765 13.7627 16.692 17.8204 8.37317 7.51731 12.5398 16.1074 15.5629 7.94524 14.3236 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 sodium/potassium/calcium exchanger 2-like [Stylophora pistillata] 3.80E-134 XP_022803384.1 sodium/potassium/calcium exchanger 2 isoform 2 Mus musculus 501 85 3.02E-167 44.691 NP_001103710 Sodium/potassium/calcium exchanger NA "calcium, potassium:sodium antiporter activity" sodium ion transmembrane transport integral component of membrane PF01699.26: Na_Ca_ex; - HyS0070.31 HyS0070.031 185 - sex-linked-abnormal - - - 29.8589 31.8821 26.9303 19.5546 45.8973 43.5369 58.0016 43.8838 27.056475 44.7171 50.9427 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - reticulocyte binding protein 2 homologue a Plasmodium falciparum 3D7 62.4 13 2.90E-08 44.361 XP_001350083 NA NA NA NA NA PF05672.13: MAP7; - HyS0057.89 HyS0057.089 186 - - 4 yes yes 9.277 0 3.8843 8.31512 2.31746 3.65991 11.6262 6.02289 5.369105 2.988685 8.824545 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 PREDICTED: coiled-coil domain-containing protein 112-like [Acropora digitifera] 3.30E-07 XP_015758665.1 coiled-coil domain-containing protein 112 isoform 1 precursor Homo sapiens 80.1 71 1.47E-16 46.617 NP_001035530 coiled-coil domain-containing protein 112 NA NA NA NA - - HyS0070.61 HyS0070.061 187 - sex-linked-abnormal - - - 7.24997 9.43944 10.1557 5.94492 5.21761 4.44481 11.7057 9.41511 8.1975075 4.83121 10.560405 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 PREDICTED: proton-coupled folate transporter-like [Hydra vulgaris] 3.90E-67 XP_002163559.3 ras-related and estrogen-regulated growth inhibitor isoform 1 Homo sapiens 146 23 6.05E-39 42.424 NP_116307 Ras-related and estrogen-regulated growth inhibitor NA GTPase activity signal transduction membrane PF00071.24: Ras; PF07690.18: MFS_1; PF08477.15: Roc; PF00025.23: Arf; PF03193.18: RsgA_GTPase; PF01926.25: MMR_HSR1; PF10960.10: Holin_BhlA; PF10236.11: DAP3; PF00910.24: RNA_helicase; PF03137.22: OATP; - HyS0067.39 HyS0067.039 188 - sex-linked-abnormal 4 yes - 42.133 24.8949 41.1604 33.2201 18.99 20.3405 30.4791 20.2417 35.3521 19.66525 25.3604 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - "gastrula zinc finger protein XlCGF57.1-like, partial " Danio rerio 112 60 2.29E-27 32.961 XP_021326474 Zinc finger protein 300 (Fragment) NA nucleic acid binding NA NA PF13894.8: zf-C2H2_4; PF13465.8: zf-H2C2_2; PF06464.13: DMAP_binding; PF00096.28: zf-C2H2; PF13912.8: zf-C2H2_6; PF12171.10: zf-C2H2_jaz; PF08271.14: TF_Zn_Ribbon; PF17032.7: zinc_ribbon_15; PF09723.12: Zn-ribbon_8; PF15909.7: zf-C2H2_8; PF18547.3: HalOD2; PF18912.2: DZR_2; PF19769.1: CPxCG_zf; PF01428.18: zf-AN1; PF05129.15: Elf1; PF05605.14: zf-Di19; PF07503.14: zf-HYPF; PF12874.9: zf-met; - HyS0070.54 HyS0070.054 189 - sex-linked-abnormal - - - 6.47764 7.84324 4.99949 1.61261 17.2169 15.7736 19.9116 24.4074 5.233245 16.49525 22.1595 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: histone-lysine N-methyltransferase NSD2-like [Hydra vulgaris] 0 XP_002164851.2 histone-lysine N-methyltransferase NSD2 isoform 1 Mus musculus 813 85 0 40.307 NP_001074571 Histone-lysine N-methyltransferase NA histone-lysine N-methyltransferase activity histone lysine methylation nucleus PF00855.19: PWWP; PF00856.30: SET; PF17907.3: AWS; PF00628.31: PHD; PF17982.3: C5HCH; PF13832.8: zf-HC5HC2H_2; PF13771.8: zf-HC5HC2H; PF03869.16: Arc; - HyS0113.27 HyS0113.027 190 - sex-linked-abnormal 4 yes - 68.2696 53.1681 55.9105 91.9886 2.35784 8.3756 10.327 11.7181 67.3342 5.36672 11.02255 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: E3 ubiquitin-protein ligase TRIM71-like [Hydra vulgaris] 3.00E-227 XP_002155572.2 E3 ubiquitin-protein ligase TRIM71 Danio rerio 430 96 2.56E-138 32.199 NP_001288260 Serine/threonine-protein kinase PknD TRIM71 zinc ion binding protein polyubiquitination integral component of membrane PF01436.23: NHL; PF00630.21: Filamin; PF17170.6: DUF5128; PF00643.26: zf-B_box; PF00097.27: zf-C3HC4; PF13445.8: zf-RING_UBOX; PF08450.14: SGL; PF13920.8: zf-C3HC4_3; PF15227.8: zf-C3HC4_4; PF13639.8: zf-RING_2; PF13923.8: zf-C3HC4_2; PF14634.8: zf-RING_5; PF16288.7: DUF4934; PF13449.8: Phytase-like; PF01731.22: Arylesterase; PF17936.3: Big_6; PF18962.2: Por_Secre_tail; - HyS0057.116 HyS0057.116 191 - - 4 yes - 23.5219 16.2836 17.154 24.2143 2.61233 3.6334 9.74473 7.2514 20.29345 3.122865 8.498065 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 G2/M phase-specific E3 ubiquitin-protein ligase [Stylophora pistillata] 1.40E-19 PFX23080.1 G2/M phase-specific E3 ubiquitin-protein ligase-like isoform X2 Danio rerio 58.5 25 7.44E-08 35.398 XP_021328572 NA NA NA NA NA PF00632.27: HECT; PF06888.14: Put_Phosphatase; - HyS0070.63 HyS0070.063 192 - sex-linked-abnormal - - - 3.75957 10.0171 2.67055 4.92147 1.87051 0.590502 5.51854 6.11406 5.3421725 1.230506 5.8163 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 predicted protein [Nematostella vectensis] 8.30E-06 XP_001641363.1 RING finger protein 24 isoform X1 Danio rerio 57 85 3.58E-10 31.868 XP_005160122 NA NA NA NA NA PF17123.7: zf-RING_11; PF13639.8: zf-RING_2; PF13923.8: zf-C3HC4_2; PF13445.8: zf-RING_UBOX; PF00097.27: zf-C3HC4; PF12678.9: zf-rbx1; PF14634.8: zf-RING_5; PF11793.10: FANCL_C; PF12861.9: zf-ANAPC11; PF06404.14: PSK; - HyS0007.360 HyS0007.360 193 - - 4 yes - 12.1957 15.1947 14.7454 10.8541 13.8439 11.2038 15.9943 17.5782 13.247475 12.52385 16.78625 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: solute carrier family 23 member 2-like [Hydra vulgaris] 1.50E-189 XP_002160774.1 solute carrier family 23 member 2-like Danio rerio 546 94 0 48.174 XP_009296238 LOW QUALITY PROTEIN: solute carrier family 23 member 1 NA transmembrane transporter activity transmembrane transport integral component of membrane PF00860.22: Xan_ur_permease; - HyS0070.79 HyS0070.079 194 - sex-linked-abnormal - - - 15.7082 20.8132 12.9406 13.5124 7.78313 13.9287 18.5765 11.0247 15.7436 10.855915 14.8006 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF07737.13: ATLF; PF15867.7: Dynein_attach_N; PF09731.11: Mitofilin; - HyS0113.34 HyS0113.034 195 - sex-linked-abnormal 4 yes - 37.6243 18.5803 34.5049 54.7094 45.0831 40.7501 56.654 36.888 36.354725 42.9166 46.771 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 EH domain-binding protein 1 [Exaiptasia pallida] 8.10E-23 KXJ10894.1 "Eps15 homology domain containing protein-binding protein 1, isoform G " Drosophila melanogaster 64.3 36 1.31E-09 30.539 NP_611179 EH domain-binding protein 1 NA NA NA integral component of membrane PF00169.31: PH; PF14593.8: PH_3; PF15413.8: PH_11; PF12814.9: Mcp5_PH; PF14491.8: DUF4435; PF12325.10: TMF_TATA_bd; PF15409.8: PH_8; PF16652.7: PH_13; - HyS0057.64 HyS0057.064 196 - - 4 yes - 20.3978 17.9215 21.5121 14.2332 25.8596 26.2376 31.2188 28.0463 18.51615 26.0486 29.63255 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: ras GTPase-activating protein 1-like [Hydra vulgaris] 0 XP_004211564.2 ras GTPase-activating protein 1 isoform X1 Danio rerio 682 97 0 42.13 XP_009300041 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide RASA1 GTPase activator activity negative regulation of Ras protein signal transduction NA PF00017.26: SH2; PF00616.21: RasGAP; PF00169.31: PH; PF00168.32: C2; PF00018.30: SH3_1; PF14604.8: SH3_9; PF07653.19: SH3_2; PF08337.14: Plexin_cytopl; PF15413.8: PH_11; - HyS0120.40 HyS0120.040 197 - sex-linked-abnormal 4 yes - 1.0565 2.49665 14.062 2.14422 0.175997 1.00098 3.9563 4.34187 4.9398425 0.5884885 4.149085 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114542728 [Dendronephthya gigantea] 2.90E-27 XP_028418000.1 uncharacterized protein LOC101885485 Danio rerio 117 81 8.76E-29 34.715 XP_005174628 NA NA NA NA NA PF04230.15: PS_pyruv_trans; - HyS0007.314 HyS0007.314 198 - - 4 yes - 7.81996 8.96111 9.15202 7.92537 12.9824 10.8226 16.131 14.1399 8.464615 11.9025 15.13545 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: NCK-interacting protein with SH3 domain-like [Hydra vulgaris] 4.50E-148 XP_012555241.1 NCK-interacting protein with SH3 domain isoform 1 Homo sapiens 317 99 1.31E-96 31.048 NP_057537 NCK-interacting protein with SH3 domain NA NA NA NA PF09431.12: DUF2013; PF00018.30: SH3_1; PF14604.8: SH3_9; PF07653.19: SH3_2; PF17902.3: SH3_10; PF15819.7: Fibin; PF12143.10: PPO1_KFDV; PF18476.3: PIN_8; - HyS0007.372 HyS0007.372 199 - - 4 yes - 3.20063 4.49161 13.5254 17.1465 0.990217 2.52831 3.66998 5.6125 9.591035 1.7592635 4.64124 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 hypothetical protein LSTR_LSTR008349 [Laodelphax striatella] 5.80E-55 RZF49063.1 carboxypeptidase A2 precursor Homo sapiens 218 94 1.22E-65 30.446 NP_001860 NA NA NA NA NA PF00246.26: Peptidase_M14; PF02244.18: Propep_M14; - HyS0057.72 HyS0057.072 200 - - 4 yes - 1.38545 2.82038 2.12696 1.30373 1.15402 1.12205 3.269 4.71414 1.90913 1.138035 3.99157 1 1 1 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: tudor domain-containing protein 1-like, partial [Hydra vulgaris]" 1.10E-44 XP_012560450.1 tudor domain-containing protein 1 Danio rerio 77 31 9.25E-13 25.904 NP_001157500 NA NA NA NA NA PF00567.26: TUDOR; PF12872.9: OST-HTH; PF06003.14: SMN; - HyS0070.36 HyS0070.036 201 - sex-linked-abnormal - - - 8.93719 6.59188 7.90034 9.37378 1.48883 2.18149 6.54007 2.59234 8.2007975 1.83516 4.566205 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 hypothetical protein BpHYR1_026962 [Brachionus plicatilis] 2.10E-06 RNA10670.1 no hits - - - - - - NA NA NA NA NA PF05822.14: UMPH-1; - HyS1699.1 HyS1699.001 202 - sex-linked-abnormal 4 yes - 21.7899 19.2679 12.692 27.3832 0.864258 2.62161 3.88498 4.97427 20.28325 1.742934 4.429625 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: uncharacterized protein LOC105844140 [Hydra vulgaris] 1.60E-26 XP_012555851.1 no hits - - - - - - NA NA NA NA NA - - HyS0070.6 HyS0070.006 203 - sex-linked-abnormal - - - 1.10493 1.34924 1.67598 2.11601 1.91436 1.50157 5.0582 3.71084 1.56154 1.707965 4.38452 1 1 1 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: armadillo repeat-containing protein 2-like [Saccoglossus kowalevskii] 1.40E-124 XP_006815976.1 armadillo repeat-containing protein 2 Danio rerio 358 97 5.35E-110 32.773 XP_683582 Armadillo repeat-containing protein 2 ARMC2 NA NA NA PF00514.25: Arm; - HyS0070.47 HyS0070.047 204 - sex-linked-abnormal - - - 12.4498 14.7218 11.1813 10.7878 16.0864 15.2576 15.2141 21.4425 12.285175 15.672 18.3283 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: serine/threonine-protein kinase 40-like [Branchiostoma belcheri] 4.70E-119 XP_019627837.1 serine/threonine-protein kinase 40 isoform X3 Danio rerio 441 95 9.08E-152 52.392 XP_693275 serine/threonine-protein kinase 40 STK40 protein kinase activity protein phosphorylation nucleoplasm PF00069.27: Pkinase; PF07714.19: PK_Tyr_Ser-Thr; PF14531.8: Kinase-like; PF17667.3: Pkinase_fungal; PF06293.16: Kdo; - HyS0057.20 HyS0057.020 205 - - 4 yes - 17.4937 21.4394 17.9254 13.0709 9.754 9.61913 13.4788 10.5285 17.48235 9.686565 12.00365 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: protein unc-13 homolog A-like [Hydra vulgaris] 0 XP_012567200.1 protein unc-13 homolog B isoform 4 Mus musculus 1206 98 0 52.71 NP_001371035 C2 calcium dependent membrane targeting NA diacylglycerol binding chemical synaptic transmission presynaptic active zone cytoplasmic component PF06292.19: MUN; PF00168.32: C2; PF00130.24: C1_1; PF08597.12: eIF3_subunit; - HyS0057.67 HyS0057.067 206 - - 4 yes - 4.38905 19.1408 14.1321 10.2414 9.12976 10.7234 12.7575 11.6182 11.9758375 9.92658 12.18785 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "muscle, skeletal receptor tyrosine-protein kinase-like [Dendronephthya gigantea]" 1.20E-28 XP_028408406.1 hepatocyte growth factor receptor isoform X2 Danio rerio 132 83 1.84E-35 43.836 XP_005163052 Hepatocyte growth factor receptor NA transmembrane receptor protein tyrosine kinase activity peptidyl-tyrosine phosphorylation integral component of membrane PF07714.19: PK_Tyr_Ser-Thr; PF00069.27: Pkinase; PF12330.10: Haspin_kinase; PF17667.3: Pkinase_fungal; PF14531.8: Kinase-like; - HyS0057.76 HyS0057.076 207 - - 4 yes - 11.0524 20.0556 16.2022 14.6921 0.853911 1.84784 3.57297 3.59687 15.500575 1.3508755 3.58492 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 "Thioredoxin, partial [Oryctes borbonicus]" 7.40E-12 KRT84796.1 Protein disulfide-isomerase Caenorhabditis elegans 74.3 7 3.43E-12 43.373 NP_491995 Large subunit ribosomal protein L7/L12 NA structural constituent of ribosome translation ribosome PF00085.22: Thioredoxin; PF04756.15: OST3_OST6; - HyS0007.352 HyS0007.352 208 - - 4 yes - 9.04936 8.24637 6.43227 6.18426 15.8292 12.9585 15.9474 17.2057 7.478065 14.39385 16.57655 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: tetratricopeptide repeat protein 24-like [Hydra vulgaris] 1.70E-62 XP_004208260.1 tetratricopeptide repeat protein 24 Homo sapiens 160 68 2.52E-41 30.591 NP_001099139 Tetratricopeptide repeat protein 24 (Fragment) NA NA NA NA PF13424.8: TPR_12; PF00515.30: TPR_1; PF13181.8: TPR_8; PF07719.19: TPR_2; PF14938.8: SNAP; PF13374.8: TPR_10; PF17874.3: TPR_MalT; PF13176.8: TPR_7; PF04212.20: MIT; PF13428.8: TPR_14; PF13432.8: TPR_16; PF10602.11: RPN7; PF14559.8: TPR_19; PF13174.8: TPR_6; PF13414.8: TPR_11; - HyS0070.4 HyS0070.004 209 - sex-linked-abnormal - - - 1.13331 0.64012 2.99926 1.80491 0.943997 0.477499 2.59734 3.17543 1.6444 0.710748 2.886385 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 Transient receptor potential cation channel subfamily A member 1-like protein [Trichoplax sp. H2] 1.70E-12 RDD37563.1 ankyrin-2 isoform 64 Homo sapiens 225 88 4.98E-62 33.888 NP_001373087 Transient receptor potential cation channel subfamily A member basal NA ion channel activity ion transmembrane transport integral component of membrane PF12796.9: Ank_2; PF13637.8: Ank_4; PF13606.8: Ank_3; PF13857.8: Ank_5; PF00023.32: Ank; PF18571.3: VWA_3_C; PF11627.10: HnRNPA1; - HyS0150.1 HyS0150.001 210 - sex-linked-abnormal - - - 0 0 0 8.5508 0 0 4.22038 0 2.1377 0 2.11019 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105438466 [Strongylocentrotus purpuratus] 5.10E-06 XP_011664593.1 no hits - - - - - - SET domain-containing protein NA NA NA NA PF19584.1: MCAfunc; - HyS0150.8 HyS0150.008 211 - sex-linked-abnormal - - - 10.6053 5.91134 11.4684 16.1281 0.4157 1.57673 2.14885 3.97544 11.028285 0.996215 3.062145 1 0 1 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - E3 ubiquitin-protein ligase TRIM17 Mus musculus 45.1 34 7.95E-04 28.682 NP_112449 NA NA NA NA NA PF00643.26: zf-B_box; PF19071.2: DUF5767; PF17370.4: DUF5392; PF17279.4: DUF5344; - HyS0120.37 HyS0120.037 212 - sex-linked-abnormal 4 yes - 1.8118 1.99467 5.5557 0.926558 0.603658 0.214684 2.98629 1.95621 2.572182 0.409171 2.47125 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114542174 isoform X2 [Dendronephthya gigantea] 5.00E-34 XP_028417721.1 uncharacterized protein LOC103912045 isoform X1 Danio rerio 143 45 3.16E-35 39.269 XP_017214352 NA NA NA NA NA PF12542.10: CWC25; PF04771.14: CAV_VP3; - HyS0007.337 HyS0007.337 213 - - 4 yes - 66.3918 57.2271 80.6913 56.8729 4.56228 7.8644 7.15852 9.26898 65.295775 6.21334 8.21375 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: adducin-related protein C1289.14-like [Hydra vulgaris] 2.90E-90 XP_012556601.1 putative adducin Schizosaccharomyces pombe 103 75 1.99E-24 30.522 NP_596838 Ribulose-5-phosphate 4-epimerase-like protein NA spectrin binding barbed-end actin filament capping plasma membrane raft PF00596.23: Aldolase_II; - HyS0113.36 HyS0113.036 214 - sex-linked-abnormal 4 yes - 14.362 11.5585 26.2235 29.1299 5.33701 7.8499 9.86912 7.31741 20.318475 6.593455 8.593265 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 hypothetical protein LOTGIDRAFT_102422 [Lottia gigantea] 1.60E-35 XP_009043711.1 Kazal-type serine peptidase inhibitor domain 2 Danio rerio 43.9 32 5.07E-04 35.526 NP_001098594 IGFBP N-terminal domain-containing protein NA insulin-like growth factor binding regulation of cell growth extracellular region PF00219.20: IGFBP; - HyS0069.32 HyS0069.032 215 - sex-linked-abnormal - - - 13.7014 9.83899 9.31218 16.5268 0.537067 2.12255 2.15308 4.45188 12.3448425 1.3298085 3.30248 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - NHL (ring finger b-box coiled coil) domain containing Caenorhabditis elegans 46.2 30 0.001 23.166 NP_498026 NA NA NA NA NA PF00531.24: Death; PF00643.26: zf-B_box; PF19071.2: DUF5767; PF15470.8: DUF4637; - HyS0113.18 HyS0113.018 216 - sex-linked-abnormal 4 yes - 4.93703 4.72855 1.1853 6.70031 0.27415 0.259918 1.41944 3.00071 4.3877975 0.267034 2.210075 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF00531.24: Death; - HyS0343.3 HyS0343.003 217 - sex-linked-abnormal - - - 0.604147 0.716902 0.545255 10.7319 0.100645 0.238651 1.72968 2.33197 3.149551 0.169648 2.030825 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein BSL78_15994 [Apostichopus japonicus] 1.00E-14 PIK47143.1 E3 ubiquitin-protein ligase TRIM56 Mus musculus 77 71 1.23E-13 24.925 NP_958761 NA NA NA NA NA PF13445.8: zf-RING_UBOX; PF15227.8: zf-C3HC4_4; PF00097.27: zf-C3HC4; PF13923.8: zf-C3HC4_2; PF13639.8: zf-RING_2; PF14634.8: zf-RING_5; PF00643.26: zf-B_box; PF13920.8: zf-C3HC4_3; PF19071.2: DUF5767; PF17279.4: DUF5344; PF05400.15: FliT; PF17315.4: FMP23; - HyS0070.44 HyS0070.044 218 - sex-linked-abnormal - - - 14.6421 18.7198 27.4769 11.3641 20.2874 17.1279 20.7861 20.2129 18.050725 18.70765 20.4995 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: spindle pole body component 110-like [Hydra vulgaris] 4.70E-29 XP_002153841.3 uncharacterized protein LOC556653 Danio rerio 73.9 8 1.04E-12 36.905 XP_009290306 NA NA NA NA NA PF01302.27: CAP_GLY; PF00096.28: zf-C2H2; - HyS0116.4 HyS0116.004 219 - sex-linked-abnormal 4 yes - 2.00359 1.0149 0.360467 3.39105 0 0 1.44222 2.05769 1.69250175 0 1.749955 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110058185 [Orbicella faveolata] 7.80E-31 XP_020620430.1 uncharacterized protein LOC101884422 Danio rerio 70.1 94 2.29E-12 23.95 XP_009290204 NA NA NA NA NA PF00632.27: HECT; PF12726.9: SEN1_N; - HyS0007.316 HyS0007.316 220 - - 4 yes - 1.02298 1.38166 3.68055 2.76946 0 0.969255 2.35676 2.10154 2.2136625 0.4846275 2.22915 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF12731.9: Mating_N; PF11757.10: RSS_P20; - HyS0007.326 HyS0007.326 221 - - 4 yes - 3.19474 3.027 11.2847 0.869237 2.0224 2.82607 5.68635 2.61783 4.59391925 2.424235 4.15209 1 1 1 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 growth arrest-specific protein 1-like [Orbicella faveolata] 6.30E-11 XP_020600886.1 growth arrest-specific protein 1a precursor Danio rerio 46.2 62 9.21E-05 26.95 NP_001104690 NA NA NA NA NA PF07127.13: Nodulin_late; - HyS0120.17 HyS0120.017 222 - sex-linked-abnormal 4 yes - 0.822838 3.3378 3.25957 8.37539 0.82245 0.909714 3.07546 2.06298 3.9488995 0.866082 2.56922 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110986593 isoform X3 [Acanthaster planci] 1.80E-10 XP_022104268.1 SET domain-containing protein 5-like Danio rerio 56.2 26 9.12E-08 38.961 XP_009302434 NA NA NA NA NA PF00856.30: SET; - HyS0070.38 HyS0070.038 223 - sex-linked-abnormal - - - 7.23706 10.4877 8.08034 5.84805 6.80103 6.18781 8.11483 8.26661 7.9132875 6.49442 8.19072 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: intersectin-1-like [Hydra vulgaris] 0 XP_012555766.1 intersectin-1 isoform 1 Mus musculus 914 91 0 43.387 NP_034717 Intersectin-1 ITSN2 Rho guanyl-nucleotide exchange factor activity regulation of Rho protein signal transduction centrosome PF00018.30: SH3_1; PF14604.8: SH3_9; PF16652.7: PH_13; PF07653.19: SH3_2; PF00621.22: RhoGEF; PF12763.9: EF-hand_4; PF00168.32: C2; PF00036.34: EF-hand_1; PF13499.8: EF-hand_7; PF00169.31: PH; PF13405.8: EF-hand_6; PF13202.8: EF-hand_5; - HyS0120.2 HyS0120.002 224 - sex-linked-abnormal 4 yes - 0 2.50428 2.67055 0 0.623505 0 2.20742 1.74687 1.2937075 0.3117525 1.977145 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.289 HyS0007.289 225 - - 4 yes - 11.9784 12.9004 16.532 21.7291 1.04881 2.7912 2.76995 4.15439 15.784975 1.920005 3.46217 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: laminin subunit alpha-1-like [Hydra vulgaris] 0 XP_012554312.1 laminin subunit alpha-1 precursor Homo sapiens 380 65 5.32E-104 29.5 NP_005550 Laminin subunit gamma-1 NA signaling receptor binding regulation of embryonic development basement membrane PF00053.26: Laminin_EGF; PF00054.25: Laminin_G_1; PF02210.26: Laminin_G_2; PF00055.19: Laminin_N; PF15711.7: ILEI; PF00168.32: C2; PF00754.27: F5_F8_type_C; PF13385.8: Laminin_G_3; PF15899.7: BNR_6; PF12474.10: PKK; PF04399.15: Glutaredoxin2_C; - HyS0116.12 HyS0116.012 226 - sex-linked-abnormal 4 yes - 4.16171 3.88112 5.25947 25.0709 9.66292 10.6861 15.1121 8.20662 9.5933 10.17451 11.65936 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC105848466 [Hydra vulgaris] 1.90E-12 XP_012564046.1 L-type lectin-domain containing receptor kinase IX.1 Glycine max 45.8 35 0.001 23.846 XP_003550213 NA NA NA NA NA PF06365.14: CD34_antigen; PF16101.7: PRIMA1; PF06024.14: Orf78; PF15807.7: MAP17; - HyS0150.2 HyS0150.002 227 - sex-linked-abnormal - - - 3.64935 2.1983 0.146312 1.38329 0.472848 0.896902 2.55612 1.7506 1.844313 0.684875 2.15336 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110986593 isoform X3 [Acanthaster planci] 4.10E-21 XP_022104268.1 SET domain-containing protein 5-like Danio rerio 99 24 1.38E-21 41.481 XP_009302434 Chromatin-remodeling protein 11 NA nucleosome binding ATP-dependent chromatin remodeling cytoskeleton PF00856.30: SET; - HyS0067.33 HyS0067.033 228 - sex-linked-abnormal 4 yes - 7.65981 7.16561 8.39261 10.2913 1.98009 2.12856 3.09952 3.89712 8.3773325 2.054325 3.49832 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: endoglucanase 4-like isoform X1 [Biomphalaria glabrata] 1.60E-05 XP_013069521.1 ephrin-B3-like Danio rerio 46.6 10 6.80E-04 32.468 XP_692670 NA NA NA NA NA PF16101.7: PRIMA1; PF05283.13: MGC-24; PF14575.8: EphA2_TM; PF03494.15: Beta-APP; - HyS0057.97 HyS0057.097 229 - - 4 yes - 13.5544 13.6635 16.6455 24.6419 0.451609 1.04035 2.43712 1.93295 17.126325 0.7459795 2.185035 1 0 1 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: protein dispatched homolog 1-like [Hydra vulgaris] 9.10E-222 XP_012567028.1 protein dispatched homolog 1 isoform X1 Danio rerio 511 89 4.67E-159 32.551 XP_017208012 Dispatched NA calcium ion binding smoothened signaling pathway integral component of membrane PF02460.20: Patched; PF12349.10: Sterol-sensing; PF03176.17: MMPL; - HyS0007.324 HyS0007.324 230 - - 4 yes - 5.36741 1.20301 1.92403 8.39276 0.89366 0.846671 2.07374 2.46407 4.2218025 0.8701655 2.268905 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 growth arrest-specific protein 1-like [Orbicella faveolata] 4.50E-11 XP_020600886.1 growth arrest-specific protein 1a precursor Danio rerio 45.1 86 9.26E-05 26.95 NP_001104690 NA NA NA NA NA PF02351.18: GDNF; - HyS0070.37 HyS0070.037 231 - sex-linked-abnormal - - - 1.74087 2.34173 1.24838 2.33469 0 0.549264 2.01703 1.19838 1.9164175 0.274632 1.607705 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: KRAB-A domain-containing protein 2-like [Aplysia californica] 1.80E-07 XP_005112451.1 no hits - - - - - - NA NA NA NA NA PF17921.3: Integrase_H2C2; PF15369.8: KIAA1328; - HyS0116.21 HyS0116.021 232 - sex-linked-abnormal 4 yes - 15.1403 16.9954 12.6476 18.7126 19.1458 20.7628 26.0894 16.4536 15.873975 19.9543 21.2715 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: cingulin-like [Hydra vulgaris] 2.90E-49 XP_012563598.1 no hits - - - - - - NA NA NA NA NA PF02183.20: HALZ; PF16700.7: SNCAIP_SNCA_bd; PF04899.14: MbeD_MobD; PF05531.14: NPV_P10; PF11180.10: DUF2968; PF08653.12: DASH_Dam1; PF07889.14: DUF1664; - HyS0113.33 HyS0113.033 233 - sex-linked-abnormal 4 yes - 34.0751 29.0141 29.5337 20.0023 3.31133 5.38339 5.29167 6.02516 28.1563 4.34736 5.658415 1 1 1 0 0 1 0 0 0 1 0 1 0 1 0 0 0 0 PREDICTED: uncharacterized protein LOC100208656 isoform X1 [Hydra vulgaris] 1.00E-10 XP_012556595.1 pleckstrin homology domain-containing family S member 1 isoform 1 Homo sapiens 43.9 40 0.002 24 NP_872407 NA NA NA NA NA PF00169.31: PH; PF12814.9: Mcp5_PH; PF02895.16: H-kinase_dim; - HyS0148.1 HyS0148.001 234 - sex-linked-abnormal - - - 23.5551 24.1975 19.7784 13.9571 1.1445 2.47987 1.97781 4.25523 20.372025 1.812185 3.11652 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF17315.4: FMP23; PF19071.2: DUF5767; PF05400.15: FliT; - HyS0113.25 HyS0113.025 235 - sex-linked-abnormal 4 yes - 206.314 213.344 145.693 166.383 1.4826 3.19466 2.5585 4.6097 182.9335 2.33863 3.5841 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: uncharacterized protein LOC100205674 [Hydra vulgaris] 4.20E-52 XP_002156354.1 no hits - - - - - - NA NA NA NA NA PF09056.13: Phospholip_A2_3; PF10083.11: DUF2321; PF17791.3: MG3; PF10013.11: DUF2256; PF13451.8: zf-trcl; PF01472.22: PUA; PF07934.14: OGG_N; PF20125.1: DUF6515; PF13920.8: zf-C3HC4_3; PF00074.22: RnaseA; - HyS0007.268 HyS0007.268 236 - - 4 yes - 2.75235 0.372735 9.32913 5.9979 0.0917027 0.347845 1.10542 1.75301 4.61302875 0.21977385 1.429215 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein ASPCAL13334 [Aspergillus calidoustus] 7.30E-05 CEL10210.1 acyl-CoA-binding domain-containing protein 6 isoform 1 Mus musculus 61.2 34 2.30E-09 30 NP_082526 NA NA NA NA NA PF12796.9: Ank_2; PF13637.8: Ank_4; PF13857.8: Ank_5; PF13606.8: Ank_3; PF00023.32: Ank; PF04518.14: Effector_1; PF08702.12: Fib_alpha; PF04977.17: DivIC; PF11382.10: MctB; - HyS0007.290 HyS0007.290 237 - - 4 yes - 11.5472 10.7593 17.4098 22.7894 0.206105 1.56376 2.59986 1.49941 15.626425 0.8849325 2.049635 1 0 1 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 Galactose-3-O-sulfotransferase 3 [Stylophora pistillata] 3.60E-102 PFX26117.1 galactosylceramide sulfotransferase Danio rerio 194 63 5.08E-55 35.159 NP_001119924 Galactosylceramide sulfotransferase GAL3ST1 galactosylceramide sulfotransferase activity glycolipid biosynthetic process Golgi apparatus PF06990.13: Gal-3-0_sulfotr; PF03567.16: Sulfotransfer_2; - HyS0148.8 HyS0148.008 238 - sex-linked-abnormal - - - 5.57582 11.2754 11.9276 6.01421 0.464442 1.28775 1.2271 2.82239 8.6982575 0.876096 2.024745 1 0 1 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - adapter molecule crk isoform 3 Mus musculus 45.4 5 1.03E-04 43.75 NP_001264150 Leucine-rich repeat protein NA NA NA NA PF00017.26: SH2; PF00531.24: Death; PF00018.30: SH3_1; - HyS0057.21 HyS0057.021 239 - - 4 yes - 6.72687 7.59107 4.0425 4.19867 3.92219 2.12535 3.69905 4.59079 5.6397775 3.02377 4.14492 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: protein unc-13 homolog A-like [Hydra vulgaris] 2.30E-45 XP_012567200.1 protein unc-13 homolog A-like Danio rerio 99 45 5.79E-21 31.633 XP_017206600 NA NA NA NA NA PF00168.32: C2; - HyS0120.41 HyS0120.041 240 - sex-linked-abnormal 4 yes - 6.90141 1.74079 9.89873 5.78584 0.287287 0.816574 1.4991 1.58343 6.0816925 0.5519305 1.541265 1 0 1 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 uncharacterized protein LOC114535575 [Dendronephthya gigantea] 7.30E-17 XP_028412660.1 uncharacterized protein LOC101884513 Danio rerio 73.9 95 2.02E-15 27.513 XP_005165515 NA NA NA NA NA - - HyS0057.111 HyS0057.111 241 - - 4 yes - 0.651866 0.661707 0.704825 2.21665 2.38906 1.7505 3.74317 2.37423 1.058762 2.06978 3.0587 1 1 1 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: trafficking protein particle complex subunit 5-like [Hydra vulgaris] 7.80E-62 XP_002161466.1 TRAPP subunit 31 Drosophila melanogaster 198 45 3.11E-62 70.149 NP_610986 Trafficking protein particle complex subunit NA D-aminoacyl-tRNA deacylase activity Golgi vesicle transport TRAPP complex PF02580.18: Tyr_Deacylase; PF04051.18: TRAPP; PF02993.16: MCPVI; - HyS0070.1 HyS0070.001 242 - sex-linked-abnormal - - - 1.25173 1.22112 1.13049 0.856846 2.39808 2.25007 3.08733 3.51339 1.1150465 2.324075 3.30036 1 1 1 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: transient receptor potential cation channel subfamily A member 1-like [Hydra vulgaris] 2.30E-112 XP_012557933.1 transient receptor potential cation channel subfamily A member 1 isoform 1 Mus musculus 421 90 5.14E-127 28.714 NP_808449 Isoform 2 of serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A NA ion channel activity ion transmembrane transport integral component of membrane PF12796.9: Ank_2; PF13637.8: Ank_4; PF00023.32: Ank; PF13857.8: Ank_5; PF13606.8: Ank_3; PF00520.33: Ion_trans; - HyS0007.259 HyS0007.259 243 - - 4 yes - 2.34334 0.395285 0.842508 4.7488 0 0 0.337823 1.60642 2.08248325 0 0.9721215 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: zinc metalloproteinase nas-11-like [Hydra vulgaris] 6.30E-08 XP_012560292.1 meprin A subunit alpha isoform X1 Homo sapiens 54.7 57 2.27E-07 29.457 XP_011512930 NA NA NA NA NA PF01400.26: Astacin; PF01549.26: ShK; - HyS0067.79 HyS0067.079 244 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0.729139 1.15566 0 0 0.9423995 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105847359 [Hydra vulgaris] 8.80E-36 XP_012562355.1 uncharacterized protein LOC108183448 isoform X1 Danio rerio 59.7 88 3.33E-09 29.534 XP_021331284 NA NA NA NA NA PF07525.18: SOCS_box; - HyS0057.35 HyS0057.035 245 - - 4 yes - 8.39992 10.9037 7.32153 11.3711 1.12557 3.69362 2.92489 3.72831 9.4990625 2.409595 3.3266 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 Heparanase [Mizuhopecten yessoensis] 2.80E-64 OWF51768.1 heparanase precursor Danio rerio 250 44 6.53E-71 37.965 NP_001038470 Heparanase NA "hydrolase activity, acting on glycosyl bonds" NA extracellular matrix PF03662.16: Glyco_hydro_79n; PF11790.10: Glyco_hydro_cc; - HyS0057.108 HyS0057.108 246 - - 4 yes - 0 0.728557 0.517388 1.46364 0.119609 0 1.23753 0.654085 0.67739625 0.0598045 0.9458075 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 zinc finger SWIM domain-containing protein 3-like [Myzus persicae] 4.70E-42 XP_022181069.1 protein FAR1-RELATED SEQUENCE 6 Glycine max 55.5 51 8.48E-08 27.885 XP_003532941 MULE domain-containing protein (Fragment) NA zinc ion binding NA integral component of membrane PF10551.11: MULE; PF00872.20: Transposase_mut; - HyS0067.14 HyS0067.014 247 - sex-linked-abnormal 4 yes - 1.52263 0.257443 0 2.0681 0 0.240497 1.09388 0.867216 0.96204325 0.1202485 0.980548 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 Pogo transposable element with KRAB domain [Exaiptasia pallida] 9.40E-18 KXJ09994.1 pogo transposable element with KRAB domain isoform 2 Homo sapiens 42 32 0.006 26.471 NP_001300943 NA NA NA NA NA - - HyS0069.58 HyS0069.058 248 - sex-linked-abnormal - - - 0 0.682699 0 4.07512 0.676894 0.320608 1.77094 0.935061 1.18945475 0.498751 1.3530005 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein K02A2.6-like [Hydra vulgaris] 5.40E-11 XP_012553983.1 uncharacterized protein K02A2.6-like Danio rerio 52.8 79 2.02E-07 31.933 XP_005173220 NA NA NA NA NA - - HyS0069.21 HyS0069.021 249 - sex-linked-abnormal - - - 6.41487 2.14149 5.70996 0 0.532677 0 0 2.22879 3.56658 0.2663385 1.114395 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0070.103 HyS0070.103 250 - sex-linked-abnormal - - - 0.974338 0.494986 0 0 0 0.0769651 0.977801 0.77535 0.367331 0.03848255 0.8765755 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105328952 [Crassostrea gigas] 6.00E-05 XP_011428330.1 uncharacterized protein LOC793688 Danio rerio 43.5 14 0.003 34.848 NP_001093522 NA NA NA NA NA PF10500.11: SR-25; PF12877.9: DUF3827; PF05793.14: TFIIF_alpha; - HyS0069.3 HyS0069.003 251 - sex-linked-abnormal - - - 2.05492 0.68986 0 0 0 0 1.19335 0.472559 0.686195 0 0.8329545 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105847402 [Hydra vulgaris] 1.30E-12 XP_012562417.1 no hits - - - - - - NA NA NA NA NA PF11594.10: Med28; - HyS0173.3 HyS0173.003 252 - sex-linked-abnormal - - - 0 0 1.13685 1.06439 0 0 0.916567 0.726176 0.55031 0 0.8213715 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC108676651 [Hyalella azteca] 9.20E-10 XP_018020256.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.353 HyS0007.353 253 - - 4 yes - 1.821 3.37501 7.94539 1.91815 0.256693 0.464865 1.0814 1.27071 3.7648875 0.360779 1.176055 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 protein NLRC3-like isoform X1 [Xiphophorus couchianus] 2.60E-19 XP_027893268.1 "NACHT, LRR and PYD domains-containing protein 3-like isoform X1 " Danio rerio 94 27 8.85E-18 24.422 XP_021323215 NA NA NA NA NA PF05729.14: NACHT; PF18738.3: HEPN_DZIP3; PF13604.8: AAA_30; PF18757.3: Nmad5; PF17776.3: NLRC4_HD2; PF12799.9: LRR_4; PF13516.8: LRR_6; PF10224.11: DUF2205; - HyS0057.69 HyS0057.069 254 - - 4 yes - 20.4278 17.2279 19.1306 17.786 0.506841 1.03003 0.871988 2.27198 18.643075 0.7684355 1.571984 1 0 1 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 peptidyl-arginine deiminase [Acinetobacter sp. WCHAc010034] 2.50E-54 WP_086374365.1 agmatine/peptidylarginine deiminase Deinococcus radiodurans 56.2 54 3.26E-07 22.222 WP_051618851 NA NA NA NA NA PF04371.17: PAD_porph; - HyS0069.33 HyS0069.033 255 - sex-linked-abnormal - - - 4.89539 3.86141 6.75819 11.074 0 0.902046 0.234565 2.23143 6.6472475 0.451023 1.2329975 1 0 1 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - tripartite motif containing 35-29 Danio rerio 45.1 43 4.99E-04 27.612 NP_001007348 NA NA NA NA NA PF00643.26: zf-B_box; PF19071.2: DUF5767; PF15470.8: DUF4637; PF08074.13: CHDCT2; PF12178.10: INCENP_N; PF05400.15: FliT; PF13419.8: HAD_2; PF02601.17: Exonuc_VII_L; PF17279.4: DUF5344; PF05873.14: Mt_ATP-synt_D; - HyS4665.1 HyS4665.001 256 - sex-linked-abnormal - - - 0 0.429133 0 0 0 0 0.546062 1.01022 0.10728325 0 0.778141 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein EGW08_000242 [Elysia chlorotica] 2.10E-77 RUS92029.1 "hypothetical protein DDB_G0286823, partial " Dictyostelium discoideum AX4 53.1 40 2.32E-06 23.611 XP_637534 Reverse transcriptase domain-containing protein (Fragment) NA metal ion binding microtubule-based movement kinesin complex PF00078.29: RVT_1; PF00628.31: PHD; PF13831.8: PHD_2; PF00130.24: C1_1; - HyS0057.44 HyS0057.044 257 - - 4 yes - 2.09945 2.81857 2.25434 0 1.39767 0.330989 1.82942 1.44884 1.79309 0.8643295 1.63913 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: tyrosine-protein kinase CSK-like [Hydra vulgaris] 2.80E-28 XP_012565373.1 tyrosine-protein kinase CSK Danio rerio 98.2 99 1.85E-23 39.333 NP_001071067 Tyrosine-protein kinase CSK CSK non-membrane spanning protein tyrosine kinase activity peptidyl-tyrosine phosphorylation cell-cell junction PF00018.30: SH3_1; PF07653.19: SH3_2; PF14604.8: SH3_9; - HyS0007.395 HyS0007.395 258 - - 4 yes - 42.1872 73.4945 49.014 50.2691 62.2656 60.2825 63.8167 60.2758 53.7412 61.27405 62.04625 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: Golgi phosphoprotein 3-like [Hydra vulgaris] 1.10E-137 XP_002157964.1 Golgi phosphoprotein 3 Mus musculus 422 99 8.53E-149 70.034 NP_079949 Golgi phosphoprotein 3 sauron NA phosphatidylinositol-4-phosphate binding Golgi organization Golgi cisterna PF05719.13: GPP34; - HyS0069.59 HyS0069.059 259 - sex-linked-abnormal - - - 53.757 18.4322 10.221 18.7644 0.746275 4.12753 2.78888 3.57164 25.29365 2.4369025 3.18026 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - E3 ubiquitin-protein ligase TRIM17 Mus musculus 44.3 62 0.001 23.963 NP_112449 NA NA NA NA NA PF00643.26: zf-B_box; PF19071.2: DUF5767; PF10256.11: Erf4; PF17279.4: DUF5344; - HyS0067.11 HyS0067.011 260 - sex-linked-abnormal 4 yes - 5.25394 10.3338 7.87281 3.77102 12.735 10.2529 11.8795 12.5818 6.8078925 11.49395 12.23065 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: band 4.1-like protein 5 [Hydra vulgaris] 5.60E-154 XP_012557768.1 band 4.1-like protein 4 Danio rerio 335 55 1.20E-103 42.76 NP_571298 Coiled-coil domain-containing protein 132 EPB41L4A cytoskeletal protein binding actomyosin structure organization cytoskeleton PF09379.12: FERM_N; PF00373.20: FERM_M; PF09380.12: FERM_C; PF08736.13: FA; - HyS0069.57 HyS0069.057 261 - sex-linked-abnormal - - - 37.3679 53.6963 18.7588 37.8498 4.29028 9.17428 4.92358 9.98993 36.9182 6.73228 7.456755 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - E3 ubiquitin-protein ligase TRIM17 Mus musculus 44.3 31 0.002 29.71 NP_112449 NA NA NA NA NA PF00643.26: zf-B_box; PF05400.15: FliT; PF19071.2: DUF5767; - HyS0007.381 HyS0007.381 262 - - 4 yes - 2.57129 1.81167 1.57167 1.3532 1.58162 2.03161 2.54611 2.51302 1.8269575 1.806615 2.529565 1 1 1 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: fanconi-associated nuclease 1-like [Hydra vulgaris] 9.50E-95 XP_012557644.1 fanconi-associated nuclease 1 Danio rerio 219 98 2.97E-62 32.057 NP_001038546 Fanconi-associated nuclease NA phosphodiesterase I activity interstrand cross-link repair nucleus PF19710.1: PIK3CG_ABD; - HyS0057.30 HyS0057.030 263 - - 4 yes - 21.1546 16.9398 14.2494 28.1664 1.71447 2.16838 2.07156 3.2428 20.12755 1.941425 2.65718 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 atrial natriuretic peptide receptor 1-like [Orbicella faveolata] 2.30E-236 XP_020600907.1 atrial natriuretic peptide receptor 1 precursor Mus musculus 620 96 0 35.344 NP_032753 Guanylate cyclase NA guanylate cyclase activity cGMP biosynthetic process integral component of membrane PF00211.22: Guanylate_cyc; PF01094.30: ANF_receptor; PF07714.19: PK_Tyr_Ser-Thr; PF00069.27: Pkinase; PF13458.8: Peripla_BP_6; PF07701.16: HNOBA; - HyS0113.14 HyS0113.014 264 - sex-linked-abnormal 4 yes yes 0 0 0 0 0 0 0.413694 0.983402 0 0 0.698548 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF12773.9: DZR; PF05207.15: zf-CSL; - HyS0007.367 HyS0007.367 265 - - 4 yes - 23.0412 19.6214 33.163 14.9206 3.67148 3.63859 4.32666 4.34402 22.68655 3.655035 4.33534 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: neural cell adhesion molecule 1-like [Hydra vulgaris] 5.30E-13 XP_002161571.3 basigin isoform 2 precursor Mus musculus 58.5 68 2.35E-09 30.597 NP_001070652 NA NA NA NA NA PF07679.18: I-set; PF13927.8: Ig_3; PF13895.8: Ig_2; PF00047.27: ig; PF16681.7: Ig_5; PF07686.19: V-set; PF15820.7: ECSCR; PF09716.12: ETRAMP; - HyS0067.66 HyS0067.066 266 - sex-linked-abnormal 4 yes - 10.3974 4.54984 10.4292 4.49632 0.227912 0.908036 1.01702 1.39615 7.46819 0.567974 1.206585 1 0 1 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: alpha-1-macroglobulin-like [Hydra vulgaris] 1.70E-242 XP_012564458.1 pregnancy zone protein precursor Homo sapiens 682 91 0 32.527 NP_002855 alpha-2-macroglobulin CPAMD8 endopeptidase inhibitor activity negative regulation of endopeptidase activity extracellular space PF07678.16: TED_complement; PF00207.24: A2M; PF07703.16: A2M_BRD; PF07677.16: A2M_recep; PF17791.3: MG3; PF01835.21: MG2; PF05326.13: SVA; PF17789.3: MG4; - HyS0343.2 HyS0343.002 267 - sex-linked-abnormal - - - 5.22763 5.07945 6.91828 1.42778 0.812817 1.15637 1.8965 1.34568 4.663285 0.9845935 1.62109 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 Neurofilament medium polypeptide [Stylophora pistillata] 1.50E-67 PFX15925.1 uncharacterized protein LOC103911530 isoform X1 Danio rerio 60.5 53 3.95E-08 21.429 XP_021326615 NA NA NA NA NA - - HyS0007.405 HyS0007.405 268 - - 4 yes - 11.0683 11.7964 20.1727 8.46663 1.88779 3.83103 2.48906 4.48645 12.8760075 2.85941 3.487755 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 "PREDICTED: uncharacterized protein LOC105843327, partial [Hydra vulgaris]" 1.60E-50 XP_012554013.1 no hits - - - - - - NA NA NA NA NA - - HyS0120.12 HyS0120.012 269 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 1.17183 0 0 0 0.585915 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.86 HyS0069.086 270 - sex-linked-abnormal - - - 0 0 0 0 0 0 1.08266 0 0 0 0.54133 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF13020.8: DUF3883; - HyS0113.43 HyS0113.043 271 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0.60317 0.477696 0 0 0.540433 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF00385.26: Chromo; - HyS4128.1 HyS4128.001 272 - sex-linked-abnormal - - - 0 0 3.74503 0.531761 0 0 0.371052 0.706266 1.06919775 0 0.538659 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: dmX-like protein 1 [Hydra vulgaris] 2.70E-202 XP_012558581.1 dmX-like protein 1 isoform X3 Mus musculus 404 97 3.34E-120 32.383 XP_006525981 DmX protein 2 DMXL1 NA vacuolar acidification RAVE complex PF12234.10: Rav1p_C; - HyS0007.401 HyS0007.401 273 - - 4 yes - 0 0.718529 4.59394 0 0 0 0.306582 0.728995 1.32811725 0 0.5177885 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC100215682 [Hydra vulgaris] 2.30E-10 NP_001274311.1 apoptosis regulator BAX isoform zeta Homo sapiens 54.7 48 5.84E-09 38.75 NP_001278360 NA NA NA NA NA PF00452.21: Bcl-2; - HyS0070.11 HyS0070.011 274 - sex-linked-abnormal - - - 4.43036 0 0 0 0 0 0 1.03273 1.10759 0 0.516365 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0473.1 HyS0473.001 275 - sex-linked-abnormal - - - 3.86746 1.04617 2.50756 7.87817 0.257709 0.855192 1.77838 0.352466 3.82484 0.5564505 1.065423 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF15595.8: Imm51; PF19071.2: DUF5767; PF12178.10: INCENP_N; PF05400.15: FliT; - HyS0007.269 HyS0007.269 276 - - 4 yes - 4.40241 9.4234 7.84819 4.32525 5.17966 5.65203 4.72553 7.05822 6.4998125 5.415845 5.891875 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2-like [Hydra vulgaris]" 8.80E-235 XP_004209493.2 "arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 " Homo sapiens 645 99 0 44.574 NP_036419 "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3" NA GTPase activator activity positive regulation of GTPase activity growth cone PF16746.7: BAR_3; PF01412.20: ArfGap; PF00169.31: PH; PF12796.9: Ank_2; PF03114.20: BAR; PF13637.8: Ank_4; PF13606.8: Ank_3; PF13857.8: Ank_5; PF15409.8: PH_8; PF09325.12: Vps5; PF00023.32: Ank; PF07526.13: POX; PF15413.8: PH_11; - HyS0057.73 HyS0057.073 277 - - 4 yes - 3.8805 5.46508 9.37536 5.30271 0.0994549 0.89615 1.19642 0.745517 6.0059125 0.49780245 0.9709685 1 0 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: uncharacterized protein LOC101238360 [Hydra vulgaris] 3.20E-119 XP_012563320.1 transporter substrate-binding domain-containing protein Synechocystis salina 65.5 14 7.63E-10 33.333 WP_194019448 SGF29 C-terminal domain-containing protein NA voltage-gated potassium channel activity potassium ion transmembrane transport voltage-gated potassium channel complex PF07885.18: Ion_trans_2; PF00520.33: Ion_trans; PF00060.28: Lig_chan; PF00497.22: SBP_bac_3; - HyS0173.9 HyS0173.009 278 - sex-linked-abnormal - - - 0 0 0 0 0 0 0.944196 0 0 0 0.472098 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114522879 [Dendronephthya gigantea] 4.30E-07 XP_028399454.1 BEN domain-containing protein 3 Mus musculus 42.4 31 0.003 38.75 NP_001346529 NA NA NA NA NA PF10523.11: BEN; - HyS0069.40 HyS0069.040 279 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0.93449 0 0 0.467245 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC113109658 isoform X2 [Carassius auratus] 1.50E-08 XP_026129177.1 no hits - - - - - - NA NA NA NA NA - - HyS0120.44 HyS0120.044 280 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0.274632 0 1.19838 0 0.137316 0.59919 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF09526.12: DUF2387; PF01803.18: LIM_bind; PF00412.24: LIM; PF05129.15: Elf1; - HyS0007.307 HyS0007.307 281 - - 4 yes - 1.20076 1.21509 1.29495 0.810808 0.200017 0.758311 1.03887 0.823328 1.130402 0.479164 0.931099 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 brachyury 2 [Dynamena pumila] 1.40E-76 QBC65504.1 T-box transcription factor T isoform 2 Homo sapiens 202 82 7.78E-63 52.85 NP_001257413 Brachyury transcription factor NA DNA-binding transcription factor activity "regulation of transcription, DNA-templated" nucleus PF00907.24: T-box; - HyS0067.15 HyS0067.015 282 - sex-linked-abnormal 4 yes - 91.9776 56.5524 49.2684 43.7466 21.9476 24.4081 25.4896 21.7593 60.38625 23.17785 23.62445 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: tetratricopeptide repeat protein 37-like [Hydra vulgaris] 2.00E-273 XP_012567129.1 tetratricopeptide repeat protein 37 Homo sapiens 615 94 0 31.041 NP_055454 Tetratricopeptide repeat protein 37 NA NA RNA catabolic process Ski complex PF00515.30: TPR_1; PF07719.19: TPR_2; PF14559.8: TPR_19; PF13432.8: TPR_16; PF13181.8: TPR_8; PF13428.8: TPR_14; PF13424.8: TPR_12; PF13431.8: TPR_17; PF13414.8: TPR_11; PF13371.8: TPR_9; PF13174.8: TPR_6; PF13176.8: TPR_7; PF12895.9: ANAPC3; PF09976.11: TPR_21; PF01239.24: PPTA; PF08238.14: Sel1; PF14561.8: TPR_20; - HyS0067.9 HyS0067.009 283 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0.890714 0 0 0.445357 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF06810.13: Phage_GP20; PF01496.21: V_ATPase_I; PF15991.7: G_path_suppress; PF10186.11: ATG14; PF05531.14: NPV_P10; PF06785.13: UPF0242; PF18504.3: Csm1_N; PF19578.1: DUF6090; PF19473.1: DUF6010; - HyS0067.63 HyS0067.063 284 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0.873437 0 0 0.4367185 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF18107.3: HTH_ABP1_N; PF13593.8: SBF_like; - HyS0007.371 HyS0007.371 285 - - 4 yes - 0 0.337621 0.898919 1.01906 0 0.236247 0.428814 0.680053 0.5639 0.1181235 0.5544335 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC107443670 [Parasteatoda tepidariorum] 1.80E-54 XP_021002126.1 carboxypeptidase A4 preproprotein Mus musculus 224 93 2.37E-67 32.864 NP_082202 Zinc carboxypeptidase NA metallocarboxypeptidase activity proteolysis extracellular space PF00246.26: Peptidase_M14; PF02244.18: Propep_M14; - HyS0113.10 HyS0113.010 286 - sex-linked-abnormal 4 yes - 0.809074 0 0.291386 0 0 0 0.465181 0.368776 0.275115 0 0.4169785 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: CBL-interacting protein kinase 26-like [Hydra vulgaris] 2.70E-38 XP_012560899.1 receptor-interacting serine/threonine-protein kinase 1 Mus musculus 71.6 69 1.33E-12 27.907 NP_001346926 Kinase domain protein NA protein serine/threonine kinase activity protein phosphorylation NA PF00069.27: Pkinase; PF07714.19: PK_Tyr_Ser-Thr; PF14531.8: Kinase-like; PF07892.13: DUF1667; - HyS0113.23 HyS0113.023 287 - sex-linked-abnormal 4 yes - 8.8864 7.58752 13.3079 8.63541 0.549181 1.56287 1.02457 1.91784 9.6043075 1.0560255 1.471205 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: ankycorbin-like isoform X1 [Hydra vulgaris] 6.70E-31 XP_012558361.1 ankycorbin isoform 2 Mus musculus 136 18 4.48E-31 34.413 NP_001343463 Uveal autoantigen with coiled-coil domains and ankyrin repeats NA NA NA NA PF12796.9: Ank_2; PF13637.8: Ank_4; PF13857.8: Ank_5; PF13606.8: Ank_3; PF00023.32: Ank; PF12799.9: LRR_4; PF13516.8: LRR_6; PF13599.8: Pentapeptide_4; PF00560.35: LRR_1; PF13855.8: LRR_8; - HyS0067.13 HyS0067.013 288 - sex-linked-abnormal 4 yes - 11.6627 11.6853 4.90779 3.97449 1.0524 1.61221 1.672 1.76776 8.05757 1.332305 1.71988 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 Brachyury [Podocoryna carnea] 5.00E-155 CAD21521.1 brachyury protein isoform X2 Danio rerio 293 62 1.02E-94 55.636 XP_009305355 Brachyury transcription factor NA DNA-binding transcription factor activity "regulation of transcription, DNA-templated" nucleus PF00907.24: T-box; - HyS0007.329 HyS0007.329 289 - - 4 yes - 12.3778 12.749 11.718 11.5955 0.0859172 0.651816 0.443737 1.05556 12.110075 0.3688666 0.7496485 1 0 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: ganglioside GM2 activator-like isoform X3 [Acropora digitifera] 4.90E-09 XP_015769770.1 ganglioside GM2 activator precursor Mus musculus 43.1 25 0.002 27.273 NP_034429 NA NA NA NA NA PF02221.17: E1_DerP2_DerF2; PF19071.2: DUF5767; PF06394.15: Pepsin-I3; - HyS0057.110 HyS0057.110 290 - - 4 yes - 1.94397 0.878666 0.467811 1.77037 0.0539747 0.153579 0.742213 0.22073 1.26520425 0.10377685 0.4814715 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein BRAFLDRAFT_67089 [Branchiostoma floridae] 6.50E-37 XP_002592665.1 Caldesmon-related protein Drosophila melanogaster 43.5 18 0.009 32.09 NP_524736 DDE-1 domain-containing protein (Fragment) NA nucleic acid binding NA integral component of membrane PF05225.18: HTH_psq; PF03221.18: HTH_Tnp_Tc5; PF03184.21: DDE_1; - HyS0070.106 HyS0070.106 291 - sex-linked-abnormal - - - 0.388389 0.263228 0.420463 0.530108 0 0 0.222548 0.529449 0.400547 0 0.3759985 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: gamma-glutamyltranspeptidase 1-like [Hydra vulgaris] 5.00E-139 XP_012556244.1 gamma-glutamyltranspeptidase 1-like Danio rerio 355 86 1.10E-114 38.596 XP_697468 Gamma-glutamyltransferase ustH NA glutathione hydrolase activity glutathione catabolic process integral component of membrane PF01019.23: G_glu_transpept; PF06791.15: TMP_2; PF08776.13: VASP_tetra; PF09532.12: FDF; - HyS0069.81 HyS0069.081 292 - sex-linked-abnormal - - - 0 0 0 0.606875 0 0 0.257524 0.408281 0.15171875 0 0.3329025 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC111344140 [Stylophora pistillata] 2.20E-47 XP_022807085.1 no hits - - - - - - Transposable element P transposase NA transposase activity "transposition, DNA-mediated" NA - - HyS0007.334 HyS0007.334 293 - - 4 yes - 1.32456 4.25751 3.10288 5.85457 0.110329 0.627687 0.950822 0.452314 3.63488 0.369008 0.701568 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105849775 [Hydra vulgaris] 2.40E-102 XP_012565667.1 uncharacterized protein Dmel_CG42529 Drosophila melanogaster 49.3 20 2.00E-05 37.037 NP_001163471 Putative serine incorporator NA NA NA integral component of membrane PF14332.8: DUF4388; - HyS0007.266 HyS0007.266 294 - - 4 yes - 88.642 120.17 115.027 159.146 0.360165 0.569159 0.414055 1.14894 120.74625 0.464662 0.7814975 1 0 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.321 HyS0007.321 295 - - 4 yes - 0 0 0 0 0 0 0.451866 0.179114 0 0 0.31549 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: importin-11 [Hydra vulgaris] 7.10E-63 XP_012554114.1 importin-11 isoform 2 Homo sapiens 102 98 9.79E-23 25.667 NP_057422 NA NA NA NA NA PF19856.1: DUF6331; - HyS0057.81 HyS0057.081 296 - - 4 yes - 3.63354 5.45961 3.7501 2.60513 0.115299 0.792933 0.395888 1.13823 3.862095 0.454116 0.767059 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0141.10 HyS0141.010 297 - sex-linked-abnormal - - - 0 0 1.4146 0 0 0.62584 1.17183 0 0.35365 0.31292 0.585915 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0057.65 HyS0057.065 298 - - 4 yes - 1.68042 3.95705 3.61613 0 5.59635 2.3861 3.89209 4.62508 2.3134 3.991225 4.258585 1 1 1 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 predicted protein [Nematostella vectensis] 1.10E-12 XP_001629720.1 wnt inhibitory factor 1 precursor Homo sapiens 47.8 66 1.39E-05 27.586 NP_009122 NA NA NA NA NA PF02019.20: WIF; - HyS0148.3 HyS0148.003 299 - sex-linked-abnormal - - - 0 0.266853 0.56856 0 0.657415 0.124661 1.1343 0.179849 0.20885325 0.391038 0.6570745 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC113475383 isoform X1 [Ciona intestinalis] 1.30E-43 XP_026695283.1 ATP-dependent DNA helicase PIF1 Danio rerio 55.1 88 4.29E-07 26.37 NP_942102 NA NA NA NA NA PF05970.16: PIF1; PF13538.8: UvrD_C_2; PF13604.8: AAA_30; - HyS0069.26 HyS0069.026 300 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0.517014 0 0 0.258507 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105847421 [Hydra vulgaris] 9.00E-08 XP_012562455.1 no hits - - - - - - NA NA NA NA NA - - HyS0070.2 HyS0070.002 301 - sex-linked-abnormal - - - 0 0 0 0 0.0765323 0.0725804 0.131695 0.522152 0 0.07455635 0.3269235 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: transient receptor potential cation channel subfamily A member 1-like [Acropora digitifera] 9.70E-06 XP_015772708.1 "ankyrin, isoform E " Drosophila melanogaster 181 78 6.71E-48 35.077 NP_001162819 Ankyrin-1 NA calcium ion binding cell differentiation integral component of membrane PF12796.9: Ank_2; PF13637.8: Ank_4; PF00023.32: Ank; PF13606.8: Ank_3; PF13857.8: Ank_5; PF05432.13: BSP_II; PF01225.27: Mur_ligase; - HyS0069.79 HyS0069.079 302 - sex-linked-abnormal - - - 0 0 0 0 0 0 0.266209 0.21102 0 0 0.2386145 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein BSL78_12013 [Apostichopus japonicus] 3.30E-11 PIK51101.1 no hits - - - - - - NA NA NA NA NA PF05501.13: DUF755; PF10500.11: SR-25; PF12877.9: DUF3827; PF05282.13: AAR2; PF06375.13: AP3D1; PF02711.16: Pap_E4; PF15279.8: SOBP; PF15763.7: DUF4692; PF15316.8: MDFI; - HyS0007.413 HyS0007.413 303 - - 4 yes - 12.5217 9.36907 18.9637 13.4059 8.31731 7.73751 7.89632 8.62977 13.5650925 8.02741 8.263045 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: dmX-like protein 1 [Hydra vulgaris] 0 XP_012558581.1 dmX-like protein 2 isoform 7 Homo sapiens 511 98 3.02E-152 31.952 NP_001365389 Putative rave regulator of v-atpase assembly complex subunit rav1/dmx protein (Fragment) DMXL1 NA vacuolar acidification RAVE complex PF12234.10: Rav1p_C; PF00400.34: WD40; PF12894.9: ANAPC4_WD40; PF08662.13: eIF2A; - HyS0113.17 HyS0113.017 304 - sex-linked-abnormal 4 yes - 0 2.55441 1.63268 0 0 0.23862 0 0.688325 1.0467725 0.11931 0.3441625 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114537410 [Dendronephthya gigantea] 5.50E-26 XP_028414266.1 transcription factor Adf-1-like isoform X2 Danio rerio 68.2 81 5.47E-12 27.675 XP_021332043 NA NA NA NA NA PF10545.11: MADF_DNA_bdg; PF02944.22: BESS; PF13873.8: Myb_DNA-bind_5; PF12776.9: Myb_DNA-bind_3; PF13837.8: Myb_DNA-bind_4; PF14906.8: DUF4495; - HyS0113.20 HyS0113.020 305 - sex-linked-abnormal 4 yes - 0 0.817153 0.290177 0.546854 0 0 0.231616 0.183616 0.413546 0 0.207616 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.34 HyS0069.034 306 - sex-linked-abnormal - - - 0 0.575186 0 0 0 0 0 0.392317 0.1437965 0 0.1961585 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF07714.19: PK_Tyr_Ser-Thr; PF00430.20: ATP-synt_B; - HyS0069.44 HyS0069.044 307 - sex-linked-abnormal - - - 0 0 0 0 0.179926 0 0.311187 0.246645 0 0.089963 0.278916 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC112594324 [Melanaphis sacchari] 1.90E-07 XP_025194839.1 no hits - - - - - - NA NA NA NA NA - - HyS0177.4 HyS0177.004 308 - sex-linked-abnormal 4 yes - 0.826353 0 0 0 0 0 0 0.3767 0.20658825 0 0.18835 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: trichohyalin-like [Acropora digitifera] 6.10E-11 XP_015779922.1 no hits - - - - - - NA NA NA NA NA PF18735.3: HEPN_RiboL-PSP; - HyS0120.3 HyS0120.003 309 - sex-linked-abnormal 4 yes - 0 0.493611 0.525816 0 0 0 0.209646 0.166208 0.25485675 0 0.187927 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC107357849 [Acropora digitifera] 5.70E-18 XP_015779976.1 MADF domain-containing protein Danio rerio 62.4 31 2.25E-10 35 NP_001315046 Transcription factor Adf-1 NA NA NA NA PF10545.11: MADF_DNA_bdg; PF13873.8: Myb_DNA-bind_5; PF00249.33: Myb_DNA-binding; - HyS0057.80 HyS0057.080 310 - - 4 yes - 0 0.127034 0.405825 0 0 0 0.107381 0.255467 0.13321475 0 0.181424 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: tudor domain-containing protein 1-like, partial [Hydra vulgaris]" 9.50E-16 XP_012560450.1 tudor domain-containing protein 1 isoform 6 Homo sapiens 48.9 41 1.39E-04 23.715 NP_001372296 NA NA NA NA NA PF00567.26: TUDOR; - HyS0057.23 HyS0057.023 311 - - 4 yes - 0.993519 1.00941 2.32921 1.01559 0.248265 0.392398 0.42734 0.564763 1.33693225 0.3203315 0.4960515 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0070.56 HyS0070.056 312 - sex-linked-abnormal - - - 1.46346 1.48797 1.58448 8.49171 0 0.17342 0.104801 0.415551 3.256905 0.08671 0.260176 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: potassium voltage-gated channel subfamily A member 10-like [Hydra vulgaris] 9.50E-45 XP_002160072.1 potassium voltage-gated channel subfamily A member 2 Danio rerio 207 81 1.74E-60 31.267 XP_003198877 NA NA NA NA NA PF02214.24: BTB_2; PF00520.33: Ion_trans; PF07885.18: Ion_trans_2; PF16017.7: BTB_3; PF00060.28: Lig_chan; - HyS0173.1 HyS0173.001 313 - sex-linked-abnormal - - - 0 0 0 0.980567 0 0 0 0.328678 0.24514175 0 0.164339 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC111102743 [Crassostrea virginica] 7.00E-08 XP_022291319.1 THAP domain-containing protein 10 Homo sapiens 41.6 45 0.006 24.855 NP_064532 NA NA NA NA NA PF05485.14: THAP; PF09612.12: HtrL_YibB; PF17762.3: HTH_ParB; - HyS0422.3 HyS0422.003 314 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0.325869 0 0 0 0.1629345 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110283498 [Parasteatoda tepidariorum] 2.10E-14 XP_021004404.1 Uncharacterized protein CELE_Y57G11C.20 Caenorhabditis elegans 55.1 37 1.37E-07 33.735 NP_502799 NA NA NA NA NA PF00617.21: RasGEF; - HyS0067.5 HyS0067.005 315 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0.315987 0 0 0.1579935 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105437092 [Strongylocentrotus purpuratus] 4.40E-05 XP_011661625.1 no hits - - - - - - NA NA NA NA NA PF07948.13: Nairovirus_M; - HyS0069.9 HyS0069.009 316 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0.315987 0 0 0.1579935 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC107454806 [Parasteatoda tepidariorum] 3.40E-21 XP_015927601.1 uncharacterized protein si:rp71-1d10.8 Danio rerio 65.9 92 2.12E-11 28.796 XP_005173216 NA NA NA NA NA PF05225.18: HTH_psq; PF13518.8: HTH_28; PF09339.12: HTH_IclR; PF01381.24: HTH_3; PF04218.15: CENP-B_N; PF08717.12: CoV_NSP8; PF09607.12: BrkDBD; PF13412.8: HTH_24; PF01022.22: HTH_5; - HyS0222.7 HyS0222.007 317 - sex-linked-abnormal - - - 0.986469 0 0 0 0.164333 0 0 0.45022 0.24661725 0.0821665 0.22511 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC111099970 [Crassostrea virginica] 6.90E-11 XP_022287216.1 no hits - - - - - - NA NA NA NA NA PF12689.9: Acid_PPase; - HyS0057.101 HyS0057.101 318 - - 4 yes - 0 0 0 0 0 0 0 0.285155 0 0 0.1425775 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC113677560 [Pocillopora damicornis] 8.70E-07 XP_027050178.1 uncharacterized protein si:ch211-108c17.2 isoform X4 Danio rerio 42.7 37 0.002 33.75 XP_021331465 NA NA NA NA NA PF07655.15: Secretin_N_2; - HyS0067.1 HyS0067.001 319 - sex-linked-abnormal 4 yes yes 0 0 0 0 0 0 0 0.283312 0 0 0.141656 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF00069.27: Pkinase; PF07714.19: PK_Tyr_Ser-Thr; PF02925.18: gpD; - HyS0070.49 HyS0070.049 320 - sex-linked-abnormal - - - 8.99706 12.8171 10.7223 5.99936 9.55506 8.24589 8.94557 9.1365 9.633955 8.900475 9.041035 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100198077 isoform X1 [Hydra vulgaris] 3.60E-189 XP_012553871.1 no hits - - - - - - NA NA NA NA NA PF02204.20: VPS9; PF13833.8: EF-hand_8; - HyS0057.125 HyS0057.125 321 - - 4 yes - 0 0.184968 0.197001 0 0.364049 0.949373 1.09706 0.497072 0.09549225 0.656711 0.797066 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "COUP-TF protein, partial [Hydractinia echinata]" 9.20E-138 AEB21388.1 nuclear receptor subfamily 2 group F member 1-A Danio rerio 373 85 3.54E-126 50.97 NP_571255 Ligand-binding domain of nuclear hormone receptor NA steroid hormone receptor activity steroid hormone mediated signaling pathway nucleus PF00105.20: zf-C4; PF00104.32: Hormone_recep; PF07619.13: DUF1581; - HyS0067.57 HyS0067.057 322 - sex-linked-abnormal 4 yes - 0 0.378984 0.268997 0.127396 0.0310161 0.0294209 0.159761 0.16895 0.19384425 0.0302185 0.1643555 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110988171 [Acanthaster planci] 1.50E-30 XP_022107154.1 G2/M phase-specific E3 ubiquitin-protein ligase-like isoform X2 Danio rerio 89.7 29 6.32E-17 22.531 XP_021328572 NA NA NA NA NA PF12558.10: DUF3744; - HyS0173.10 HyS0173.010 323 - sex-linked-abnormal - - - 0 0 0 0 0 0 0.190676 0.0756074 0 0 0.1331417 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE22759 [Exaiptasia pallida] 1.50E-46 KXJ07606.1 uncharacterized protein si:ch73-7i4.2 Danio rerio 95.9 51 4.30E-19 24.373 XP_002663431 NA NA NA NA NA PF18804.3: CxC3; - HyS0067.42 HyS0067.042 324 - sex-linked-abnormal 4 yes - 0.228378 0.154923 0.3299 0.624734 0.0380459 0.036088 0.130692 0.207306 0.33448375 0.03706695 0.168999 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 zinc metalloproteinase nas-4-like [Acanthaster planci] 4.10E-37 XP_022083878.1 Zinc metalloproteinase nas-8 Caenorhabditis elegans 142 20 3.39E-35 36.458 NP_501114 Fibroblast growth factor receptor substrate 2 SR-CI chitin binding chitin metabolic process extracellular region PF01400.26: Astacin; PF01549.26: ShK; - HyS0067.68 HyS0067.068 325 - sex-linked-abnormal 4 yes - 0.595164 0.504472 0.64459 0.406651 0.0495745 0.0470207 0.085195 0.270261 0.53771925 0.0482976 0.177728 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE27887 [Exaiptasia pallida] 8.00E-94 KXJ14739.1 kinesin family member 4 Danio rerio 46.2 16 0.002 23.214 NP_957117 NA NA NA NA NA - - HyS0177.2 HyS0177.002 326 - sex-linked-abnormal 4 yes - 0 0.169246 0.180247 0.681114 0 0 0.143309 0.113636 0.25765175 0 0.1284725 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC105442970 [Strongylocentrotus purpuratus] 5.60E-56 XP_011673977.1 uncharacterized protein si:ch211-235f1.3 isoform X3 Danio rerio 82.8 83 2.21E-15 25.189 XP_017211444 NA NA NA NA NA PF00589.24: Phage_integrase; - HyS0069.43 HyS0069.043 327 - sex-linked-abnormal - - - 0 0.448781 0.637235 0 0 0 0.253134 0 0.271504 0 0.126567 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110250330 [Exaiptasia pallida] 7.40E-41 XP_020912589.1 uncharacterized protein si:ch73-7i4.2 Danio rerio 131 41 2.83E-31 31.429 XP_002663431 CxC3 domain-containing protein NA NA NA integral component of membrane PF18758.3: KDZ; PF17437.4: DUF5416; - HyS0007.260 HyS0007.260 328 - - 4 yes - 7.2611 7.28279 7.64549 4.34078 0.0504014 0.382439 0.259859 0.412169 6.63254 0.2164202 0.336014 1 0 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF14200.8: RicinB_lectin_2; PF13774.8: Longin; - HyS0177.8 HyS0177.008 329 - sex-linked-abnormal 4 yes - 0.795762 0.269038 0 0.540176 0 0.125686 0 0.362673 0.401244 0.062843 0.1813365 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "steroid 17-alpha-hydroxylase/17,20 lyase-like [Pocillopora damicornis]" 7.40E-44 XP_027050678.1 cytochrome P450 2AA6 Danio rerio 154 99 7.79E-42 29.221 NP_001186898 NA NA NA NA NA PF00067.24: p450; PF07753.13: DUF1609; - HyS0069.71 HyS0069.071 330 - sex-linked-abnormal - - - 0 0 0.364222 0 0 0 0 0.231043 0.0910555 0 0.1155215 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF07851.15: TMPIT; PF20025.1: DUF6433; PF05852.13: DUF848; PF05207.15: zf-CSL; PF17448.4: YqaH; PF00170.23: bZIP_1; - HyS0244.2 HyS0244.002 331 - sex-linked-abnormal - - - 1.34463 2.92042 1.65174 2.57797 0.156803 0.148745 0.307559 0.213452 2.12369 0.152774 0.2605055 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 alpha-2-macroglobulin [Diadumene lineata] 1.40E-249 BAJ05271.1 pregnancy zone protein precursor Homo sapiens 705 93 0 33.262 NP_002855 Alpha-2-macroglobulin NA endopeptidase inhibitor activity negative regulation of endopeptidase activity extracellular space PF07678.16: TED_complement; PF07703.16: A2M_BRD; PF00207.24: A2M; PF07677.16: A2M_recep; PF17791.3: MG3; PF01835.21: MG2; PF17789.3: MG4; PF05326.13: SVA; PF11656.10: DUF3811; - HyS0120.15 HyS0120.015 332 - sex-linked-abnormal 4 yes - 0 0.191995 0 0 0 0.0895942 0.162723 0.129024 0.04799875 0.0447971 0.1458735 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0723.1 HyS0723.001 333 - X_Z - - - 0 0.102008 0 0 0 0 0.128942 0.0681804 0.025502 0 0.0985612 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105846614 [Hydra vulgaris] 5.60E-75 XP_012561014.1 N-lysine methyltransferase KMT5A isoform 4 Homo sapiens 90.9 10 9.85E-19 39.189 NP_001311435 NA NA NA NA NA PF07535.14: zf-DBF; PF00856.30: SET; PF06304.13: DUF1048; PF13495.8: Phage_int_SAM_4; PF05605.14: zf-Di19; PF05129.15: Elf1; - HyS0069.69 HyS0069.069 334 - sex-linked-abnormal - - - 7.03204 9.03907 15.7098 8.1247 1.40575 1.3329 1.00991 1.92163 9.9764025 1.369325 1.46577 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - NHL (ring finger b-box coiled coil) domain containing Caenorhabditis elegans 46.6 62 2.65E-04 21.053 NP_498026 NA NA NA NA NA PF00643.26: zf-B_box; PF19071.2: DUF5767; PF11112.10: PyocinActivator; PF08074.13: CHDCT2; PF17370.4: DUF5392; - HyS0069.80 HyS0069.080 335 - sex-linked-abnormal - - - 0 0.113436 0.12079 0 0 0 0.191668 0 0.0585565 0 0.095834 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC111335808 isoform X1 [Stylophora pistillata] 2.70E-48 XP_022797535.1 uncharacterized protein LOC121174714 Glycine max 73.2 25 4.34E-13 28.485 XP_040870560 CCHC-type domain-containing protein (Fragment) NA RNA-directed DNA polymerase activity DNA integration integral component of membrane PF00098.25: zf-CCHC; PF13696.8: zf-CCHC_2; PF00096.28: zf-C2H2; PF13894.8: zf-C2H2_4; PF14787.8: zf-CCHC_5; PF16644.7: NEXCaM_BD; - HyS0120.13 HyS0120.013 336 - sex-linked-abnormal 4 yes - 0 0.275815 0 0 0 0 0 0.185953 0.06895375 0 0.0929765 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 reverse transcriptase [Lasius niger] 1.40E-31 KMQ88340.1 no hits - - - - - - NA NA NA NA NA PF13966.8: zf-RVT; PF04488.17: Gly_transf_sug; PF17586.4: DUF5485; - HyS0120.47 HyS0120.047 337 - sex-linked-abnormal 4 yes - 0 0.121177 0 0 0 0 0 0.162422 0.03029425 0 0.081211 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105437092 [Strongylocentrotus purpuratus] 1.20E-26 XP_011661625.1 uncharacterized protein LOC100005990 Danio rerio 52.4 32 1.42E-05 25.701 XP_005171592 NA NA NA NA NA - - HyS0070.89 HyS0070.089 338 - sex-linked-abnormal - - - 0.68428 0.231944 0.246984 2.33633 0 0.270296 0.195974 0.233122 0.8748845 0.135148 0.214548 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: gamma-glutamyltranspeptidase 1-like [Hydra vulgaris] 7.10E-176 XP_012556244.1 gamma-glutamyltranspeptidase 1 isoform X1 Danio rerio 418 99 4.03E-138 40.306 XP_017212782 Gamma-glutamyltranspeptidase GGT1 glutathione hydrolase activity glutathione catabolic process vesicle PF01019.23: G_glu_transpept; PF08776.13: VASP_tetra; - HyS0057.75 HyS0057.075 339 - - 4 yes - 0.7556 0.683336 0.363789 0.172194 0.0839176 0 0 0.228667 0.49372975 0.0419588 0.1143335 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene5150 [Stylophora pistillata] 6.30E-21 PFX30044.1 no hits - - - - - - NA NA NA NA NA PF03564.17: DUF1759; PF18107.3: HTH_ABP1_N; PF03396.17: Pox_RNA_pol_35; PF16297.7: DUF4939; PF10369.11: ALS_ss_C; PF14479.8: HeLo; PF20075.1: DUF6471; PF03417.18: AAT; PF13996.8: YobH; PF05553.13: DUF761; PF00653.23: BIR; PF02748.17: PyrI_C; - HyS0007.386 HyS0007.386 340 - - 4 yes - 0.978541 2.32202 2.47255 2.67338 3.74937 2.31922 2.80212 3.4074 2.11162275 3.034295 3.10476 1 1 1 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: gamma-tubulin complex component 4-like [Hydra vulgaris] 6.00E-216 XP_004206016.1 gamma-tubulin complex component 4 isoform b Homo sapiens 511 97 4.52E-173 42.813 NP_055259 Gamma-tubulin complex component TUBGCP4 gamma-tubulin binding microtubule nucleation spindle pole PF04130.15: GCP_C_terminal; PF17681.3: GCP_N_terminal; PF16669.7: TTC5_OB; - HyS0113.13 HyS0113.013 341 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0.140164 0 0 0.070082 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC107338686 [Acropora digitifera] 1.30E-37 XP_015759403.1 uncharacterized protein LOC101883290 isoform X1 Danio rerio 128 96 3.49E-31 29.235 XP_005161423 NA NA NA NA NA PF05103.15: DivIVA; PF04820.16: Trp_halogenase; - HyS0343.1 HyS0343.001 342 - sex-linked-abnormal - - - 1.03392 1.04725 3.34773 0.699665 0 0.163267 0.297771 0 1.53214125 0.0816335 0.1488855 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0116.9 HyS0116.009 343 - sex-linked-abnormal 4 yes - 0.718882 0.243152 0 0.488479 0.239515 0 0.206511 0.163725 0.36262825 0.1197575 0.185118 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: uncharacterized protein LOC105850628, partial [Hydra vulgaris]" 3.40E-18 XP_012566534.1 E3 ubiquitin-protein ligase TRIM31 isoform X3 Homo sapiens 50.1 23 1.11E-05 38.667 XP_011512568 NA NA NA NA NA PF13445.8: zf-RING_UBOX; PF13923.8: zf-C3HC4_2; PF12560.10: RAG1_imp_bd; PF15227.8: zf-C3HC4_4; PF00097.27: zf-C3HC4; PF14835.8: zf-RING_6; PF14634.8: zf-RING_5; PF13639.8: zf-RING_2; PF02891.22: zf-MIZ; PF11264.10: ThylakoidFormat; PF14570.8: zf-RING_4; PF05207.15: zf-CSL; PF11789.10: zf-Nse; PF18073.3: Rubredoxin_2; PF13717.8: zinc_ribbon_4; - HyS0255.2 HyS0255.002 344 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0.0978992 0 0 0.0489496 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC109475736 [Branchiostoma belcheri] 1.90E-36 XP_019632058.1 uncharacterized protein LOC102662047 Glycine max 46.2 29 7.15E-04 24.667 XP_040870606 NA NA NA NA NA PF02992.16: Transposase_21; - HyS0113.7 HyS0113.007 345 - sex-linked-abnormal 4 yes - 0 0 0 0 0.25345 0 0 0.348654 0 0.126725 0.174327 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110043603 [Orbicella faveolata] 1.50E-23 XP_020604733.1 G2/M phase-specific E3 ubiquitin-protein ligase-like isoform X2 Danio rerio 73.6 72 3.04E-14 37.879 XP_021328572 NA NA NA NA NA - - HyS4646.1 HyS4646.001 346 - sex-linked-abnormal - - - 0 0 0 2.37757 0 0 0 0.0879463 0.5943925 0 0.04397315 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 E3 ubiquitin-protein ligase TRIM33-like [Acanthaster planci] 4.00E-14 XP_022086171.1 tripartite motif-containing protein 16-like Danio rerio 70.1 86 6.81E-12 22.789 XP_686669 NA NA NA NA NA PF13445.8: zf-RING_UBOX; PF13639.8: zf-RING_2; PF15227.8: zf-C3HC4_4; PF00097.27: zf-C3HC4; PF13923.8: zf-C3HC4_2; PF13920.8: zf-C3HC4_3; PF00643.26: zf-B_box; PF14634.8: zf-RING_5; PF09171.12: AGOG; - HyS0620.3 HyS0620.003 347 - sex-linked-abnormal 4 yes - 2.47955 1.34358 3.57729 0.67591 0.0826137 0.235037 0.284405 0.112759 2.0190825 0.15882535 0.198582 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0067.56 HyS0067.056 348 - sex-linked-abnormal 4 yes - 0 0.326531 0.347916 0 0 0.15267 0 0.220578 0.16861175 0.076335 0.110289 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114532163 [Dendronephthya gigantea] 2.70E-18 XP_028409542.1 no hits - - - - - - NA NA NA NA NA - - HyS0173.7 HyS0173.007 349 - sex-linked-abnormal - - - 0 0 0 0 0 0.144722 0 0.209008 0 0.072361 0.104504 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE18723 [Exaiptasia pallida] 4.80E-10 KXJ08049.1 no hits - - - - - - NA NA NA NA NA PF13663.8: DUF4148; - HyS0057.55 HyS0057.055 350 - - 4 yes - 0.635228 1.55219 1.05575 3.306 0.0423296 0.0401545 0 0.144047 1.637292 0.04124205 0.0720235 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC107095177 [Cyprinodon variegatus] 7.00E-21 XP_015246653.1 vascular endothelial growth factor receptor 1 isoform 1 precursor Homo sapiens 75.5 10 4.45E-12 36.747 NP_002010 NA NA NA NA NA PF06119.16: NIDO; PF07714.19: PK_Tyr_Ser-Thr; PF17870.3: Insulin_TMD; PF10743.11: Phage_Cox; - HyS0173.6 HyS0173.006 351 - sex-linked-abnormal - - - 0.881146 0.298507 0.158947 0 0 0.0696063 0.126278 0 0.33465 0.03480315 0.063139 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE17048 [Exaiptasia pallida] 1.60E-48 KXJ29169.1 uncharacterized protein si:ch73-30l9.1 Danio rerio 82.8 62 2.33E-15 22.36 XP_001338892 NA NA NA NA NA PF00632.27: HECT; PF11976.10: Rad60-SLD; - HyS0141.8 HyS0141.008 352 - sex-linked-abnormal - - - 0 0.0843208 0 0 0 0 0 0.0564306 0.0210802 0 0.0282153 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114542174 isoform X2 [Dendronephthya gigantea] 2.70E-59 XP_028417721.1 uncharacterized protein LOC103909690 Danio rerio 211 47 8.99E-56 32.944 XP_017209257 NA NA NA NA NA PF00589.24: Phage_integrase; - HyS0069.49 HyS0069.049 353 - sex-linked-abnormal - - - 0 0 0 0 0.0692924 0 0.119195 0 0 0.0346462 0.0595975 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105849049 [Hydra vulgaris] 1.20E-54 XP_012564787.1 uncharacterized protein LOC101882356 Danio rerio 61.6 24 6.16E-09 30.645 XP_009300577 NA NA NA NA NA PF09090.13: MIF4G_like_2; - HyS0007.294 HyS0007.294 354 - - 4 yes - 2.9011 18.6688 8.72021 0.988686 0 0.763882 0.138634 0.659585 7.819699 0.381941 0.3991095 1 0 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 follistatin-A isoform X2 [Sipha flava] 2.20E-40 XP_025418659.1 follistatin-A precursor Danio rerio 123 90 1.11E-31 33.793 NP_571112 Ovomucoid NA serine-type endopeptidase inhibitor activity negative regulation of endopeptidase activity NA PF07648.17: Kazal_2; PF00050.23: Kazal_1; - HyS0328.4 HyS0328.004 355 - sex-linked-abnormal - - - 1.96351 7.31491 2.83285 1.33819 0.245326 0.620406 0.42226 0.446442 3.362365 0.432866 0.434351 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - tripartite motif containing 35-29 Danio rerio 44.7 39 8.89E-04 27.407 NP_001007348 NA NA NA NA NA PF00643.26: zf-B_box; PF19071.2: DUF5767; PF15470.8: DUF4637; PF08074.13: CHDCT2; PF12178.10: INCENP_N; PF17315.4: FMP23; PF02601.17: Exonuc_VII_L; PF13419.8: HAD_2; PF05400.15: FliT; PF17279.4: DUF5344; - HyS0007.271 HyS0007.271 356 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105845888 [Hydra vulgaris] 4.10E-20 XP_012559572.1 no hits - - - - - - NA NA NA NA NA PF06217.14: GAGA_bind; - HyS0007.272 HyS0007.272 357 - - 4 yes yes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105845888 [Hydra vulgaris] 1.90E-39 XP_012559572.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.274 HyS0007.274 358 - - 4 yes yes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105845888 [Hydra vulgaris] 5.00E-40 XP_012559572.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.279 HyS0007.279 359 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF01400.26: Astacin; PF02099.19: Josephin; - HyS0007.281 HyS0007.281 360 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 predicted protein [Nematostella vectensis] 1.40E-28 XP_001634200.1 Uncharacterized protein CELE_C24G7.4 Caenorhabditis elegans 79.7 92 1.91E-14 23.587 NP_001309477 NA NA NA NA NA PF00858.26: ASC; PF15932.7: DUF4748; - HyS0007.283 HyS0007.283 361 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 amiloride-sensitive sodium channel subunit beta-2-like [Exaiptasia pallida] 1.70E-19 XP_020892112.1 Uncharacterized protein CELE_C24G7.4 Caenorhabditis elegans 71.6 61 1.79E-12 28.634 NP_001309477 NA NA NA NA NA PF00858.26: ASC; - HyS0007.286 HyS0007.286 362 - - 4 yes - 0 0 1.12385 0 0 0 0 0 0.2809625 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.287 HyS0007.287 363 - - 4 yes - 0 0 0.165726 0 0 0 0 0 0.0414315 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 predicted protein [Nematostella vectensis] 6.30E-29 XP_001634200.1 Uncharacterized protein CELE_C24G7.4 Caenorhabditis elegans 79.3 92 2.34E-14 23.782 NP_001309477 NA NA NA NA NA PF00858.26: ASC; PF15932.7: DUF4748; - HyS0007.288 HyS0007.288 364 - - 4 yes - 0 0.454646 0.161392 0.915198 0 0 0 0 0.382809 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 acid-sensing ion channel 4-A-like [Pocillopora damicornis] 4.00E-23 XP_027056495.1 DEgenerin Like Caenorhabditis elegans 68.2 93 7.10E-11 20.736 NP_492230 NA NA NA NA NA PF00858.26: ASC; - HyS0007.315 HyS0007.315 365 - - 4 yes - 0 0.642664 0.685285 0 0 0 0 0 0.33198725 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC107357849 [Acropora digitifera] 6.40E-07 XP_015779976.1 no hits - - - - - - NA NA NA NA NA PF10545.11: MADF_DNA_bdg; - HyS0007.343 HyS0007.343 366 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: antistasin-like [Aplysia californica] 8.40E-06 XP_005093524.1 no hits - - - - - - NA NA NA NA NA PF02822.16: Antistasin; PF05198.18: IF3_N; - HyS0007.345 HyS0007.345 367 - - 4 yes - 0 0 0.102199 0 0 0 0 0 0.02554975 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene11474 [Stylophora pistillata] 7.00E-77 PFX23934.1 uncharacterized protein LOC101884422 Danio rerio 181 47 2.83E-47 30.861 XP_009290204 RNA-directed DNA polymerase from mobile element jockey NA ubiquitin-protein transferase activity protein ubiquitination extracellular matrix PF00632.27: HECT; - HyS0007.348 HyS0007.348 368 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.382 HyS0007.382 369 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105844140 [Hydra vulgaris] 5.40E-19 XP_012555851.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.383 HyS0007.383 370 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: tigger transposable element-derived protein 4-like [Acropora digitifera] 5.00E-11 XP_015749342.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.384 HyS0007.384 371 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 ATP-dependent DNA helicase Q1 [Stylophora pistillata] 3.50E-23 PFX18468.1 phosphatidylglycerol lysyltransferase domain-containing protein Clostridioides difficile 39.7 82 0.005 25.806 WP_004454768 ATP-dependent DNA helicase Q1 NA helicase activity NA integral component of membrane PF08797.13: HIRAN; - HyS0007.389 HyS0007.389 372 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - gamma-tubulin complex component 4 isoform X2 Homo sapiens 40.4 27 7.43E-04 73.077 XP_016877567 NA NA NA NA NA - - HyS0007.392 HyS0007.392 373 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114538154 [Dendronephthya gigantea] 4.50E-25 XP_028415072.1 sentrin 15 Mus musculus 57.4 47 5.65E-08 29.032 NP_001186885 NA NA NA NA NA PF02902.21: Peptidase_C48; PF00770.20: Peptidase_C5; PF03412.17: Peptidase_C39; - HyS0007.394 HyS0007.394 374 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF10500.11: SR-25; PF12877.9: DUF3827; PF06988.13: NifT; PF05501.13: DUF755; - HyS0007.398 HyS0007.398 375 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.399 HyS0007.399 376 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.404 HyS0007.404 377 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF16911.7: PapA_C; - HyS0007.406 HyS0007.406 378 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF11022.10: ATP19; - HyS0007.408 HyS0007.408 379 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0057.3 HyS0057.003 380 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - pyridoxal kinase Plasmodium falciparum 3D7 105 99 1.73E-23 36.496 XP_966146 Histone acetyltransferase ENT1 histone acetyltransferase activity histone H3 acetylation MOZ/MORF histone acetyltransferase complex - - HyS0057.5 HyS0057.005 381 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - "DDRGK domain-containing protein, putative " Plasmodium falciparum 3D7 50.1 26 4.40E-05 35.043 XP_001347884 NA NA NA NA NA - - HyS0057.37 HyS0057.037 382 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: P2X purinoceptor 7-like isoform X1 [Acropora digitifera] 8.00E-15 XP_015765908.1 no hits - - - - - - NA NA NA NA NA - - HyS0057.38 HyS0057.038 383 - - 4 yes - 0 0 0 2.01674 0 0 0 0 0.504185 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0057.39 HyS0057.039 384 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: E3 ubiquitin-protein ligase RNF220-like [Hydra vulgaris] 6.10E-24 XP_004208086.1 no hits - - - - - - E3 ubiquitin-protein ligase RNF220 NA ubiquitin-protein transferase activity protein ubiquitination NA PF15926.7: RNF220; PF12269.10: CpG_bind_C; PF09788.11: Tmemb_55A; PF09798.11: LCD1; PF03226.16: Yippee-Mis18; PF18608.3: XAF1_C; - HyS0057.60 HyS0057.060 385 - - 4 yes - 0 2.92806 0 0 0 0 0 0 0.732015 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF03914.19: CBF; - HyS0057.83 HyS0057.083 386 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF12329.10: TMF_DNA_bd; PF10473.11: CENP-F_leu_zip; PF11559.10: ADIP; PF16808.7: PKcGMP_CC; PF05218.16: DUF713; PF05377.13: FlaC_arch; PF19111.2: DUF5798; - HyS0057.100 HyS0057.100 387 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105329205 [Crassostrea gigas] 5.60E-07 XP_011428697.1 no hits - - - - - - NA NA NA NA NA - - HyS0057.102 HyS0057.102 388 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC102801657 [Saccoglossus kowalevskii] 4.50E-24 XP_006824607.1 "uncharacterized protein LOC108182213, partial " Danio rerio 42.4 88 3.46E-04 21.186 XP_017209869 Reverse transcriptase domain-containing protein NA aspartic-type endopeptidase activity DNA integration NA PF14893.8: PNMA; PF03732.19: Retrotrans_gag; PF00656.24: Peptidase_C14; PF07853.13: DUF1648; - HyS0057.127 HyS0057.127 389 - - 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0067.2 HyS0067.002 390 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0067.6 HyS0067.006 391 - sex-linked-abnormal 4 yes yes 0 0 0.5549 0 0 0 0 0 0.138725 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF04513.14: Baculo_PEP_C; PF02465.20: FliD_N; PF01519.18: DUF16; PF05008.17: V-SNARE; PF13931.8: Microtub_bind; PF04102.14: SlyX; PF05440.14: MtrB; PF15508.8: NAAA-beta; - HyS0067.41 HyS0067.041 392 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF12487.10: DUF3703; - HyS0067.51 HyS0067.051 393 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0067.53 HyS0067.053 394 - sex-linked-abnormal 4 yes - 0 0 0.813127 0.764124 0 0 0 0 0.39431275 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: alpha-1-macroglobulin-like [Priapulus caudatus] 8.70E-05 XP_014679564.1 complement C3 preproprotein Homo sapiens 45.4 27 2.73E-04 39.437 NP_000055 NA NA NA NA NA PF07677.16: A2M_recep; - HyS0067.54 HyS0067.054 395 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC100635271 [Amphimedon queenslandica] 1.90E-27 XP_011403635.1 no hits - - - - - - DDE-1 domain-containing protein NA nucleic acid binding NA NA - - HyS0067.58 HyS0067.058 396 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene10853 [Stylophora pistillata] 1.00E-61 PFX24545.1 no hits - - - - - - ZAD domain-containing protein NA zinc ion binding NA nucleus PF05557.15: MAD; PF06497.13: DUF1098; PF08650.12: DASH_Dad4; PF14071.8: YlbD_coat; - HyS0067.59 HyS0067.059 397 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene15820 [Stylophora pistillata] 1.60E-12 PFX19747.1 poils au dos Drosophila melanogaster 53.1 34 7.88E-07 33.333 NP_650534 NA NA NA NA NA PF07776.17: zf-AD; PF01121.22: CoaE; - HyS0067.60 HyS0067.060 398 - sex-linked-abnormal 4 yes - 0 0 0.635522 0 0 0 0 0 0.1588805 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC100197852 [Hydra vulgaris] 3.80E-10 XP_012555623.1 no hits - - - - - - NA NA NA NA NA - - HyS0067.61 HyS0067.061 399 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0067.62 HyS0067.062 400 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: uncharacterized protein LOC106512151, partial [Austrofundulus limnaeus]" 1.30E-04 XP_013856284.1 uncharacterized protein si:ch211-235f1.3 isoform X3 Danio rerio 48.9 59 4.13E-06 37.5 XP_017211444 NA NA NA NA NA PF14616.8: DUF4451; - HyS0067.67 HyS0067.067 401 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0067.72 HyS0067.072 402 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 N-lysine methyltransferase KMT5A-like [Dendronephthya gigantea] 5.30E-20 XP_028414258.1 uncharacterized protein LOC103909690 Danio rerio 72 44 8.44E-13 34.615 XP_017209257 N-lysine methyltransferase SETD8 NA methyltransferase activity methylation NA PF00856.30: SET; - HyS0067.78 HyS0067.078 403 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0113.2 HyS0113.002 404 - sex-linked-abnormal 4 yes yes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF13393.8: tRNA-synt_His; - HyS0113.3 HyS0113.003 405 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114538102 [Dendronephthya gigantea] 2.80E-04 XP_028415023.1 no hits - - - - - - NA NA NA NA NA - - HyS0113.4 HyS0113.004 406 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110043603 [Orbicella faveolata] 1.50E-23 XP_020604733.1 G2/M phase-specific E3 ubiquitin-protein ligase-like isoform X2 Danio rerio 73.6 72 3.04E-14 37.879 XP_021328572 NA NA NA NA NA - - HyS0113.5 HyS0113.005 407 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 G2/M phase-specific E3 ubiquitin-protein ligase [Exaiptasia pallida] 6.60E-33 KXJ06448.1 G2/M phase-specific E3 ubiquitin-protein ligase-like isoform X2 Danio rerio 64.3 52 2.17E-10 27.273 XP_021328572 NA NA NA NA NA - - HyS0113.6 HyS0113.006 408 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 Protein RTF2-like [Exaiptasia pallida] 1.90E-30 KXJ18385.1 G2/M phase-specific E3 ubiquitin-protein ligase-like Danio rerio 83.6 75 2.70E-19 35.537 XP_021325967 G2/M phase-specific E3 ubiquitin-protein ligase NA ubiquitin-protein transferase activity protein ubiquitination NA PF00632.27: HECT; - HyS0113.8 HyS0113.008 409 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 G2/M phase-specific E3 ubiquitin-protein ligase [Exaiptasia pallida] 6.60E-33 KXJ06448.1 G2/M phase-specific E3 ubiquitin-protein ligase-like isoform X2 Danio rerio 64.3 52 2.17E-10 27.273 XP_021328572 NA NA NA NA NA - - HyS0113.9 HyS0113.009 410 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110232530 [Exaiptasia pallida] 1.60E-34 XP_020893403.1 G2/M phase-specific E3 ubiquitin-protein ligase-like Danio rerio 86.3 91 1.91E-20 33.793 XP_021325967 G2/M phase-specific E3 ubiquitin-protein ligase NA ubiquitin-protein transferase activity protein ubiquitination NA PF00632.27: HECT; - HyS0113.11 HyS0113.011 411 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC113112899 isoform X3 [Carassius auratus] 6.00E-23 XP_026134601.1 SET domain-containing protein 5-like Danio rerio 117 40 4.16E-29 45.385 XP_009302434 Histone-lysine N-methyltransferase NA methyltransferase activity methylation integral component of membrane PF00856.30: SET; PF07714.19: PK_Tyr_Ser-Thr; PF00069.27: Pkinase; - HyS0113.12 HyS0113.012 412 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF19558.1: DUF6080; - HyS0113.22 HyS0113.022 413 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0113.42 HyS0113.042 414 - sex-linked-abnormal 4 yes yes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC109484858 isoform X2 [Branchiostoma belcheri] 1.10E-06 XP_019643777.1 no hits - - - - - - NA NA NA NA NA PF09011.12: HMG_box_2; PF00505.21: HMG_box; PF06382.13: Protamine_like; PF00046.31: Homeodomain; PF05930.14: Phage_AlpA; - HyS0116.5 HyS0116.005 415 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene15206 [Stylophora pistillata] 3.80E-21 PFX20338.1 putative UBA/UAS domain-containing protein Ucp10 Schizosaccharomyces pombe 42.7 30 0.005 27.907 NP_588339 NA NA NA NA NA PF07516.15: SecA_SW; - HyS0116.10 HyS0116.010 416 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE26449 [Exaiptasia pallida] 2.80E-42 KXJ26834.1 no hits - - - - - - NA NA NA NA NA PF00096.28: zf-C2H2; PF12171.10: zf-C2H2_jaz; PF13894.8: zf-C2H2_4; PF16278.7: zf-C2HE; - HyS0116.13 HyS0116.013 417 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF10545.11: MADF_DNA_bdg; PF06584.15: DIRP; - HyS0116.14 HyS0116.014 418 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0116.15 HyS0116.015 419 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0116.18 HyS0116.018 420 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105333833 [Crassostrea gigas] 5.10E-29 XP_011435340.1 zinc finger MYM-type protein 1 isoform b Homo sapiens 45.4 77 0.001 26.875 NP_001276020 NA NA NA NA NA PF16828.7: GAGBD; PF19074.2: DUF5770; - HyS0116.20 HyS0116.020 421 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110248008 [Exaiptasia pallida] 4.30E-07 XP_020910151.1 uncharacterized protein LOC103910778 Danio rerio 38.1 98 0.006 25.455 XP_021331042 NA NA NA NA NA PF18858.3: LPD39; PF18383.3: IFT81_CH; PF00746.23: Gram_pos_anchor; - HyS0116.23 HyS0116.023 422 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0116.24 HyS0116.024 423 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0120.1 HyS0120.001 424 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114538408 isoform X1 [Dendronephthya gigantea] 4.80E-29 XP_028415388.1 no hits - - - - - - NA NA NA NA NA PF00651.33: BTB; - HyS0120.4 HyS0120.004 425 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF06818.17: Fez1; PF15742.7: DUF4686; PF00769.21: ERM; PF02183.20: HALZ; PF09727.11: CortBP2; PF10303.11: DUF2408; PF07798.13: DUF1640; PF10498.11: IFT57; PF17253.4: DUF5320; PF06156.15: YabA; PF01496.21: V_ATPase_I; PF16360.7: GTP-bdg_M; PF15188.8: CCDC-167; PF09418.12: DUF2009; PF04871.15: Uso1_p115_C; PF10211.11: Ax_dynein_light; - HyS0120.6 HyS0120.006 426 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0120.7 HyS0120.007 427 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE6317 [Exaiptasia pallida] 3.00E-106 KXJ25582.1 no hits - - - - - - NA NA NA NA NA - - HyS0120.8 HyS0120.008 428 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC100198017 [Hydra vulgaris] 3.60E-08 XP_012565456.1 no hits - - - - - - NA NA NA NA NA PF18780.3: HNH_repeat; - HyS0120.10 HyS0120.010 429 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0120.14 HyS0120.014 430 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110373173 [Helicoverpa armigera] 2.20E-08 XP_021186027.1 uncharacterized protein si:rp71-1d10.8 Danio rerio 50.8 55 4.47E-06 29.008 XP_005173216 NA NA NA NA NA PF05225.18: HTH_psq; PF13518.8: HTH_28; PF09339.12: HTH_IclR; PF01381.24: HTH_3; PF13412.8: HTH_24; PF02796.17: HTH_7; PF05043.15: Mga; - HyS0120.19 HyS0120.019 431 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 Uncharacterized protein K02A2.6 [Exaiptasia pallida] 6.60E-36 KXJ20512.1 "uncharacterized protein LOC108182213, partial " Danio rerio 112 72 1.94E-27 26.966 XP_017209869 Transposon Ty3-I Gag-Pol polyprotein NA aspartic-type endopeptidase activity DNA integration NA PF00098.25: zf-CCHC; PF13650.8: Asp_protease_2; PF14893.8: PNMA; PF03732.19: Retrotrans_gag; PF13917.8: zf-CCHC_3; PF13975.8: gag-asp_proteas; - HyS0120.22 HyS0120.022 432 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein BOX15_Mlig021084g3 [Macrostomum lignano] 5.90E-07 PAA49614.1 no hits - - - - - - NA NA NA NA NA PF00078.29: RVT_1; - HyS0120.23 HyS0120.023 433 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF00096.28: zf-C2H2; PF13894.8: zf-C2H2_4; PF13909.8: zf-H2C2_5; PF17017.7: zf-C2H2_aberr; PF16622.7: zf-C2H2_11; PF14353.8: CpXC; PF18868.3: zf-C2H2_3rep; - HyS0120.24 HyS0120.024 434 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC106161284 isoform X1 [Lingula anatina] 2.90E-36 XP_013393642.1 calcium-responsive transcription factor isoform 1 Mus musculus 49.7 61 3.16E-05 20 NP_631889 NA NA NA NA NA PF15299.8: ALS2CR8; PF02888.18: CaMBD; - HyS0120.26 HyS0120.026 435 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF19336.1: DUF5921; - HyS0120.27 HyS0120.027 436 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF14583.8: Pectate_lyase22; - HyS0120.28 HyS0120.028 437 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF16900.7: REPA_OB_2; - HyS0120.29 HyS0120.029 438 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein C0J52_18914 [Blattella germanica] 1.10E-07 PSN42454.1 no hits - - - - - - NA NA NA NA NA PF05667.13: DUF812; PF08286.13: Spc24; PF10146.11: zf-C4H2; PF05478.13: Prominin; PF15397.8: DUF4618; PF10779.11: XhlA; PF12128.10: DUF3584; PF00769.21: ERM; PF19220.2: Crescentin; PF02050.18: FliJ; PF13949.8: ALIX_LYPXL_bnd; PF01519.18: DUF16; PF06273.13: eIF-4B; PF08702.12: Fib_alpha; PF07851.15: TMPIT; PF03961.15: FapA; PF05929.13: Phage_GPO; PF04859.14: DUF641; PF14362.8: DUF4407; PF10473.11: CENP-F_leu_zip; PF06009.14: Laminin_II; PF05911.13: FPP; PF17835.3: NOG1_N; PF03078.17: ATHILA; PF04912.16: Dynamitin; PF15619.8: Lebercilin; PF10498.11: IFT57; PF05549.13: Allexi_40kDa; PF00804.27: Syntaxin; PF01920.22: Prefoldin_2; PF09787.11: Golgin_A5; PF03938.16: OmpH; PF17045.7: CEP63; PF07889.14: DUF1664; PF17107.7: SesA; PF01496.21: V_ATPase_I; PF16515.7: HIP1_clath_bdg; PF02601.17: Exonuc_VII_L; PF14712.8: Snapin_Pallidin; PF13863.8: DUF4200; PF10186.11: ATG14; PF12795.9: MscS_porin; PF11622.10: DUF3251; PF10046.11: BLOC1_2; PF03462.20: PCRF; PF05615.15: THOC7; PF16326.7: ABC_tran_CTD; PF14523.8: Syntaxin_2; PF07303.15: Occludin_ELL; PF04102.14: SlyX; PF05377.13: FlaC_arch; PF16378.7: DUF4988; PF13094.8: CENP-Q; PF02346.18: Vac_Fusion; PF09969.11: DUF2203; - HyS0120.30 HyS0120.030 439 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0120.31 HyS0120.031 440 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF14529.8: Exo_endo_phos_2; PF03372.25: Exo_endo_phos; - HyS0120.32 HyS0120.032 441 - sex-linked-abnormal 4 yes - 0 0.231991 0 0 0 0 0 0 0.05799775 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0120.33 HyS0120.033 442 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein pdam_00024823 [Pocillopora damicornis] 4.40E-17 RMX42715.1 uncharacterized protein LOC103910150 Danio rerio 63.2 21 2.77E-09 42.169 XP_021324012 NA NA NA NA NA PF03564.17: DUF1759; - HyS0120.34 HyS0120.034 443 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 Enzymatic polyprotein [Exaiptasia pallida] 4.90E-04 KXJ08313.1 no hits - - - - - - NA NA NA NA NA - - HyS0120.35 HyS0120.035 444 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC107584155 isoform X1 [Sinocyclocheilus grahami] 3.40E-46 XP_016126124.1 no hits - - - - - - NA NA NA NA NA PF02992.16: Transposase_21; PF18759.3: Plavaka; - HyS0120.36 HyS0120.036 445 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105440338 [Strongylocentrotus purpuratus] 6.20E-13 XP_011668645.1 casein kinase like 13 Arabidopsis thaliana 57.4 54 1.08E-07 27.619 NP_171939 NA NA NA NA NA PF00069.27: Pkinase; PF07714.19: PK_Tyr_Ser-Thr; PF06293.16: Kdo; PF03109.18: ABC1; PF19974.1: TCAD9; PF01636.25: APH; - HyS0120.38 HyS0120.038 446 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene20812 [Stylophora pistillata] 4.60E-10 PFX14994.1 G2/M phase-specific E3 ubiquitin-protein ligase-like isoform X2 Danio rerio 55.1 32 9.69E-07 27.922 XP_021328572 NA NA NA NA NA PF04438.18: zf-HIT; - HyS0120.39 HyS0120.039 447 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114538408 isoform X1 [Dendronephthya gigantea] 9.40E-08 XP_028415388.1 no hits - - - - - - NA NA NA NA NA - - HyS0120.43 HyS0120.043 448 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0120.45 HyS0120.045 449 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0120.46 HyS0120.046 450 - sex-linked-abnormal 4 yes - 0 0.131878 0 0 0 0 0 0 0.0329695 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 Neurofilament medium polypeptide [Stylophora pistillata] 2.30E-22 PFX15925.1 no hits - - - - - - NA NA NA NA NA - - HyS0177.1 HyS0177.001 451 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF14918.8: MTBP_N; - HyS0177.7 HyS0177.007 452 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 ATP-dependent DNA helicase PIF1-like [Dendronephthya gigantea] 3.10E-15 XP_028416424.1 uncharacterized protein LOC101882679 Danio rerio 43.1 35 0.001 36.585 XP_021330385 NA NA NA NA NA - - HyS0177.9 HyS0177.009 453 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: steroid 17-alpha-hydroxylase/17,20 lyase-like [Saccoglossus kowalevskii]" 7.30E-12 XP_002730828.1 "cytochrome P450, family 71, subfamily B, polypeptide 17 " Arabidopsis thaliana 59.7 68 3.80E-10 38.298 NP_189247 2-methylbutanal oxime monooxygenase NA "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" oxidation-reduction process integral component of membrane PF00067.24: p450; PF01070.20: FMN_dh; - HyS0422.1 HyS0422.001 454 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF12171.10: zf-C2H2_jaz; - HyS0422.2 HyS0422.002 455 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "hypothetical protein X975_15030, partial [Stegodyphus mimosarum]" 1.10E-08 KFM83404.1 no hits - - - - - - NA NA NA NA NA - - HyS0422.4 HyS0422.004 456 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.1 HyS0069.001 457 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.2 HyS0069.002 458 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein BSL78_26845 [Apostichopus japonicus] 1.70E-14 PIK36317.1 no hits - - - - - - NA NA NA NA NA PF11594.10: Med28; - HyS0069.4 HyS0069.004 459 - sex-linked-abnormal - - - 0 0.0967351 0 0 0 0 0 0 0.024183775 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC107343731 [Acropora digitifera] 9.70E-13 XP_015764807.1 no hits - - - - - - NA NA NA NA NA PF13966.8: zf-RVT; PF05443.13: ROS_MUCR; PF00856.30: SET; PF12815.9: CTD; PF00794.20: PI3K_rbd; - HyS0069.5 HyS0069.005 460 - sex-linked-abnormal - - - 0 0 0.138216 0 0 0 0 0 0.034554 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 predicted protein [Nematostella vectensis] 6.90E-43 XP_001629303.1 uncharacterized protein LOC108183448 isoform X1 Danio rerio 54.7 47 1.80E-06 24.345 XP_021331284 NA NA NA NA NA PF18737.3: HEPN_MAE_28990; PF05887.13: Trypan_PARP; - HyS0069.6 HyS0069.006 461 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF16746.7: BAR_3; PF12732.9: YtxH; PF18315.3: VCH_CASS14; - HyS0069.7 HyS0069.007 462 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF08240.14: ADH_N; - HyS0069.10 HyS0069.010 463 - sex-linked-abnormal - - - 0.996633 0 0 0 0 0 0 0 0.24915825 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC108676651 [Hyalella azteca] 1.20E-23 XP_018020256.1 uncharacterized protein si:rp71-1d10.8 Danio rerio 50.1 88 1.04E-05 24.242 XP_005173216 HTH CENPB-type domain-containing protein NA nucleic acid binding NA nucleus PF03184.21: DDE_1; - HyS0069.12 HyS0069.012 464 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF00527.20: E7; PF05129.15: Elf1; - HyS0069.14 HyS0069.014 465 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 N-lysine methyltransferase KMT5A-like [Dendronephthya gigantea] 1.20E-12 XP_028414258.1 SET domain-containing protein 5-like Danio rerio 61.6 14 4.67E-09 39.024 XP_009302434 NA NA NA NA NA - - HyS0069.17 HyS0069.017 466 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.18 HyS0069.018 467 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - Glycerophosphodiester phosphodiesterase NA ubiquitin conjugating enzyme binding DNA integration THO complex part of transcription export complex - - HyS0069.22 HyS0069.022 468 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC107584155 isoform X1 [Sinocyclocheilus grahami] 1.40E-47 XP_016126124.1 uncharacterized protein LOC102662047 Glycine max 44.7 16 0.002 29.114 XP_040870606 NA NA NA NA NA PF02992.16: Transposase_21; PF18759.3: Plavaka; - HyS0069.24 HyS0069.024 469 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF13401.8: AAA_22; PF05673.15: DUF815; PF13191.8: AAA_16; PF00005.29: ABC_tran; PF00437.22: T2SSE; PF13555.8: AAA_29; - HyS0069.25 HyS0069.025 470 - sex-linked-abnormal - - - 0 0.489507 0 0 0 0 0 0 0.12237675 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: heparanase-like [Hydra vulgaris] 1.30E-49 XP_002166563.3 heparanase isoform 1 preproprotein Homo sapiens 108 97 2.46E-26 36.559 NP_001092010 Heparanase (Fragment) NA "hydrolase activity, acting on glycosyl bonds" NA membrane PF03662.16: Glyco_hydro_79n; PF01997.18: Translin; PF01731.22: Arylesterase; - HyS0069.27 HyS0069.027 471 - sex-linked-abnormal - - - 0 0 0 0.41255 0 0 0 0 0.1031375 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC100374871 [Saccoglossus kowalevskii] 8.40E-13 XP_006815518.1 zinc finger protein 862 isoform X4 Homo sapiens 71.2 90 5.10E-12 21.965 XP_024302634 NA NA NA NA NA PF05699.16: Dimer_Tnp_hAT; PF17459.4: DUF5422; PF02976.17: MutH; - HyS0069.28 HyS0069.028 472 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF19220.2: Crescentin; PF08614.13: ATG16; PF06818.17: Fez1; PF05531.14: NPV_P10; PF15934.7: Yuri_gagarin; PF13738.8: Pyr_redox_3; PF06009.14: Laminin_II; PF04102.14: SlyX; - HyS0069.29 HyS0069.029 473 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110452122 [Mizuhopecten yessoensis] 3.10E-32 XP_021356135.1 uncharacterized protein si:ch211-235f1.3 isoform X1 Danio rerio 112 91 6.29E-27 32.301 XP_021331607 NA NA NA NA NA - - HyS0069.30 HyS0069.030 474 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene10853 [Stylophora pistillata] 6.30E-34 PFX24545.1 no hits - - - - - - ZAD domain-containing protein NA zinc ion binding NA nucleus PF16401.7: DUF5009; PF08650.12: DASH_Dad4; - HyS0069.35 HyS0069.035 475 - sex-linked-abnormal - - - 0 1.16463 0 0 0 0 0 0 0.2911575 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF01166.20: TSC22; PF07989.13: Cnn_1N; PF09177.13: Syntaxin-6_N; PF06818.17: Fez1; - HyS0069.36 HyS0069.036 476 - sex-linked-abnormal - - - 1.95142 0 0 1.305 0 0 0 0 0.814105 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.37 HyS0069.037 477 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF14747.8: DUF4473; PF09888.11: DUF2115; PF00046.31: Homeodomain; PF17363.4: DUF5388; PF09139.13: Tam41_Mmp37; - HyS0069.38 HyS0069.038 478 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC109484857 [Branchiostoma belcheri] 3.60E-70 XP_019643775.1 uncharacterized protein si:ch73-7i4.2 Danio rerio 53.9 28 3.74E-06 28.188 XP_002663431 B box-type domain-containing protein (Fragment) NA zinc ion binding NA NA PF18758.3: KDZ; - HyS0069.41 HyS0069.041 479 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - uncharacterized protein LOC793688 Danio rerio 38.1 81 0.002 36.508 NP_001093522 NA NA NA NA NA PF16064.7: DUF4806; - HyS0069.42 HyS0069.042 480 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE12115 [Exaiptasia pallida] 4.20E-04 KXJ05520.1 no hits - - - - - - NA NA NA NA NA - - HyS0069.47 HyS0069.047 481 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein RF55_17547 [Lasius niger] 8.70E-09 KMQ84563.1 uncharacterized protein K02A2.6-like Danio rerio 60.1 86 6.09E-10 36.765 XP_021329765 NA NA NA NA NA - - HyS0069.48 HyS0069.048 482 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC107333563 [Acropora digitifera] 6.70E-12 XP_015753880.1 no hits - - - - - - NA NA NA NA NA PF06217.14: GAGA_bind; PF03235.16: DUF262; - HyS0069.51 HyS0069.051 483 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 reverse transcriptase [Lasius niger] 2.60E-24 KMQ88340.1 no hits - - - - - - NA NA NA NA NA PF13966.8: zf-RVT; - HyS0069.52 HyS0069.052 484 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.53 HyS0069.053 485 - sex-linked-abnormal - - - 1.31501 0 0 0 0 0 0 0 0.3287525 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF13794.8: MiaE_2; PF14276.8: DUF4363; PF02265.18: S1-P1_nuclease; PF19145.2: DUF5827; PF01042.23: Ribonuc_L-PSP; - HyS0069.54 HyS0069.054 486 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.55 HyS0069.055 487 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 O-acetyl-ADP-ribose deacetylase [Firmicutes bacterium CAG:24053_14] 6.60E-05 OLA42918.1 hypothetical protein PA3693 Pseudomonas aeruginosa PAO1 44.7 15 1.39E-04 60.606 NP_252383 NA NA NA NA NA PF01661.23: Macro; - HyS0069.56 HyS0069.056 488 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.60 HyS0069.060 489 - sex-linked-abnormal - - - 0 0.958421 0 0.481391 0 0 0 0 0.359953 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110042396 [Orbicella faveolata] 4.30E-13 XP_020603419.1 no hits - - - - - - NA NA NA NA NA PF01336.27: tRNA_anti-codon; PF09904.11: HTH_43; - HyS0069.61 HyS0069.061 490 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.62 HyS0069.062 491 - sex-linked-abnormal - - - 0 0 1.26415 2.33273 0 0 0 0 0.89922 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.64 HyS0069.064 492 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 P2X purinoceptor 7-like [Exaiptasia pallida] 2.90E-05 XP_020911659.1 no hits - - - - - - NA NA NA NA NA PF08240.14: ADH_N; - HyS0069.65 HyS0069.065 493 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC109049388 [Cyprinus carpio] 2.00E-49 XP_018922640.1 uncharacterized protein LOC101882356 Danio rerio 113 99 1.06E-28 32.599 XP_009300577 NA NA NA NA NA - - HyS0069.66 HyS0069.066 494 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.67 HyS0069.067 495 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.68 HyS0069.068 496 - sex-linked-abnormal - - - 0 0 0.44974 0 0 0 0 0 0.112435 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC107584155 isoform X1 [Sinocyclocheilus grahami] 3.60E-25 XP_016126124.1 no hits - - - - - - NA NA NA NA NA PF14860.8: DrrA_P4M; PF02577.16: DUF151; PF15300.8: INT_SG_DDX_CT_C; - HyS0069.72 HyS0069.072 497 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF15648.8: Tox-REase-5; - HyS0069.73 HyS0069.073 498 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - SET domain-containing protein 5-like Danio rerio 44.7 33 4.70E-05 46.154 XP_009302434 NA NA NA NA NA - - HyS0069.74 HyS0069.074 499 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110240470 [Exaiptasia pallida] 3.50E-04 XP_020901944.1 no hits - - - - - - NA NA NA NA NA PF10779.11: XhlA; - HyS0069.75 HyS0069.075 500 - sex-linked-abnormal - - - 0 0.144653 0 0 0 0 0 0 0.03616325 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105847359 [Hydra vulgaris] 1.50E-36 XP_012562355.1 no hits - - - - - - NA NA NA NA NA PF12910.9: PHD_like; PF13720.8: Acetyltransf_11; PF10905.10: DUF2695; PF09740.11: DUF2043; - HyS0069.76 HyS0069.076 501 - sex-linked-abnormal - - - 1.74087 0 0 0 0 0 0 0 0.4352175 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF05129.15: Elf1; PF01803.18: LIM_bind; - HyS0069.77 HyS0069.077 502 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.82 HyS0069.082 503 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene14766 [Stylophora pistillata] 1.60E-28 PFX20767.1 no hits - - - - - - NA NA NA NA NA PF08020.13: DUF1706; - HyS0069.83 HyS0069.083 504 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: uncharacterized protein LOC105850818, partial [Hydra vulgaris]" 6.00E-08 XP_012566680.1 no hits - - - - - - NA NA NA NA NA PF05531.14: NPV_P10; PF06103.13: DUF948; PF14056.8: DUF4250; PF04210.15: MtrG; PF08656.12: DASH_Dad3; PF12998.9: ING; PF06009.14: Laminin_II; PF08702.12: Fib_alpha; PF10388.11: YkuI_C; PF10046.11: BLOC1_2; PF00038.23: Filament; PF07889.14: DUF1664; - HyS0069.87 HyS0069.087 505 - sex-linked-abnormal - - - 0 0.555733 0 0 0 0 0 0 0.13893325 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF08232.14: Striatin; PF18829.3: Importin_rep_6; PF04889.14: Cwf_Cwc_15; PF07149.13: Pes-10; - HyS0069.88 HyS0069.088 506 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 ATP-dependent DNA helicase PIF1 [Exaiptasia pallida] 1.30E-08 KXJ16219.1 uncharacterized protein si:dkey-249d8.1 Danio rerio 42.4 85 0.001 22.699 XP_005172178 NA NA NA NA NA PF01336.27: tRNA_anti-codon; - HyS0070.3 HyS0070.003 507 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF07972.13: Flavodoxin_NdrI; - HyS0070.55 HyS0070.055 508 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 tetratricopeptide repeat protein 28-like [Dendronephthya gigantea] 4.80E-04 XP_028419292.1 no hits - - - - - - NA NA NA NA NA - - HyS0070.77 HyS0070.077 509 - sex-linked-abnormal - - - 0.296669 0.100585 0 0 0 0 0 0 0.0993135 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC111333252 [Stylophora pistillata] 1.00E-43 XP_022794532.1 hypothetical protein DDB_G0284913 Dictyostelium discoideum AX4 49.3 9 1.54E-04 35.938 XP_639929 NA NA NA NA NA PF19667.1: DUF6170; PF07699.15: Ephrin_rec_like; PF20063.1: DUF6462; PF12173.10: BacteriocIIc_cy; PF02415.19: Chlam_PMP; - HyS0070.78 HyS0070.078 510 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0070.86 HyS0070.086 511 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: cell division cycle 5-related protein-like [Hydra vulgaris] 9.60E-26 XP_012560016.1 cell division cycle 5-like protein Danio rerio 123 71 3.30E-33 90 NP_957378 Pre-mRNA-splicing factor cef-1 CDC5L DNA binding cell division Prp19 complex PF00249.33: Myb_DNA-binding; PF13921.8: Myb_DNA-bind_6; PF11626.10: Rap1_C; - HyS0070.87 HyS0070.087 512 - sex-linked-abnormal - - yes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0070.88 HyS0070.088 513 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0070.92 HyS0070.092 514 - sex-linked-abnormal - - yes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - Pyroglutamylated RFamide peptide receptor NA G protein-coupled receptor activity G protein-coupled receptor signaling pathway integral component of membrane - - HyS0070.94 HyS0070.094 515 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114544067 [Dendronephthya gigantea] 3.30E-14 XP_028418615.1 uncharacterized protein si:ch211-207i20.3 isoform X2 Danio rerio 43.5 44 2.81E-04 37.5 XP_683419 NA NA NA NA NA PF02944.22: BESS; - HyS0070.95 HyS0070.095 516 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: uncharacterized protein LOC105849301, partial [Hydra vulgaris]" 1.40E-12 XP_012565104.1 no hits - - - - - - NA NA NA NA NA - - HyS0070.96 HyS0070.096 517 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF05501.13: DUF755; PF12877.9: DUF3827; PF10500.11: SR-25; PF15376.8: DUF4603; PF00257.21: Dehydrin; PF05793.14: TFIIF_alpha; PF17061.7: PARM; PF14631.8: FancD2; - HyS0070.98 HyS0070.098 518 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein DSY43_02735 [Gammaproteobacteria bacterium] 1.10E-71 RUA06172.1 no hits - - - - - - NA NA NA NA NA PF01057.19: Parvo_NS1; PF01637.20: ATPase_2; PF00910.24: RNA_helicase; PF00519.19: PPV_E1_C; PF13173.8: AAA_14; PF13521.8: AAA_28; - HyS0070.99 HyS0070.099 519 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105328952 [Crassostrea gigas] 1.10E-04 XP_011428330.1 no hits - - - - - - NA NA NA NA NA PF10500.11: SR-25; PF12877.9: DUF3827; PF05501.13: DUF755; PF15376.8: DUF4603; PF14631.8: FancD2; PF05793.14: TFIIF_alpha; PF00257.21: Dehydrin; - HyS0070.100 HyS0070.100 520 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114535406 [Dendronephthya gigantea] 5.60E-67 XP_028412523.1 no hits - - - - - - NA NA NA NA NA PF01057.19: Parvo_NS1; PF01637.20: ATPase_2; PF00519.19: PPV_E1_C; PF00910.24: RNA_helicase; PF13173.8: AAA_14; PF13521.8: AAA_28; PF13191.8: AAA_16; - HyS0070.101 HyS0070.101 521 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC111120498 [Crassostrea virginica] 5.70E-17 XP_022316952.1 no hits - - - - - - NA NA NA NA NA PF10500.11: SR-25; PF12877.9: DUF3827; PF15376.8: DUF4603; - HyS0070.102 HyS0070.102 522 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114535406 [Dendronephthya gigantea] 5.60E-67 XP_028412523.1 no hits - - - - - - NA NA NA NA NA PF01057.19: Parvo_NS1; PF01637.20: ATPase_2; PF00519.19: PPV_E1_C; PF00910.24: RNA_helicase; PF13173.8: AAA_14; PF13521.8: AAA_28; PF13191.8: AAA_16; - HyS0070.104 HyS0070.104 523 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF10500.11: SR-25; PF05501.13: DUF755; PF12877.9: DUF3827; PF15376.8: DUF4603; PF05793.14: TFIIF_alpha; - HyS0070.105 HyS0070.105 524 - sex-linked-abnormal - - yes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: uncharacterized protein LOC105843862, partial [Hydra vulgaris]" 2.00E-10 XP_012555213.1 no hits - - - - - - NA NA NA NA NA - - HyS0070.107 HyS0070.107 525 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF04665.14: Pox_A32; PF05707.14: Zot; - HyS0070.108 HyS0070.108 526 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein CAPTEDRAFT_185673 [Capitella teleta] 2.30E-62 ELU12291.1 no hits - - - - - - NA NA NA NA NA PF16903.7: Capsid_N; - HyS0070.109 HyS0070.109 527 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF13860.8: FlgD_ig; - HyS0070.110 HyS0070.110 528 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF15248.8: DUF4587; - HyS0070.111 HyS0070.111 529 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF03700.15: Sorting_nexin; - HyS0070.112 HyS0070.112 530 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110059588 [Orbicella faveolata] 6.10E-07 XP_020621975.1 uncharacterized protein LOC101883107 Danio rerio 48.9 84 1.38E-06 30.303 XP_005156758 NA NA NA NA NA - - HyS0070.113 HyS0070.113 531 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114534730 [Dendronephthya gigantea] 2.30E-14 XP_028411998.1 uncharacterized protein LOC108182681 Danio rerio 41.2 48 0.004 25.806 XP_021326643 NA NA NA NA NA PF13936.8: HTH_38; PF18701.3: DUF5641; PF18024.3: HTH_50; PF13411.8: MerR_1; - HyS0070.114 HyS0070.114 532 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114534730 [Dendronephthya gigantea] 2.30E-14 XP_028411998.1 uncharacterized protein LOC108182681 Danio rerio 41.2 48 0.004 25.806 XP_021326643 NA NA NA NA NA PF13936.8: HTH_38; PF18701.3: DUF5641; PF18024.3: HTH_50; PF13411.8: MerR_1; - HyS0070.115 HyS0070.115 533 - sex-linked-abnormal - - yes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110059588 [Orbicella faveolata] 1.40E-06 XP_020621975.1 uncharacterized protein LOC101883107 Danio rerio 47 84 6.85E-06 30.303 XP_005156758 NA NA NA NA NA - - HyS0070.116 HyS0070.116 534 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF03700.15: Sorting_nexin; - HyS0070.117 HyS0070.117 535 - sex-linked-abnormal - - yes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF15248.8: DUF4587; - HyS0070.118 HyS0070.118 536 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0070.123 HyS0070.123 537 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF18054.3: CEL_III_C; - HyS0070.124 HyS0070.124 538 - sex-linked-abnormal - - - 0 2.70679 0 0 0 0 0 0 0.6766975 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF17315.4: FMP23; - HyS0141.1 HyS0141.001 539 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114537981 isoform X2 [Dendronephthya gigantea] 3.30E-63 XP_028414895.1 uncharacterized protein LOC541543 isoform X1 Danio rerio 124 56 3.37E-28 28.109 XP_005168586 NA NA NA NA NA PF00632.27: HECT; PF02845.18: CUE; PF00964.19: Elicitin; - HyS0141.2 HyS0141.002 540 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 ATP-dependent DNA helicase PIF6 [Exaiptasia pallida] 1.50E-13 KXJ16773.1 uncharacterized protein K02A2.6 Danio rerio 77.4 33 2.33E-13 26.768 XP_005158326 NA NA NA NA NA PF00098.25: zf-CCHC; PF13975.8: gag-asp_proteas; PF13650.8: Asp_protease_2; PF13917.8: zf-CCHC_3; - HyS0141.4 HyS0141.004 541 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0141.5 HyS0141.005 542 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 reverse transcriptase [Lasius niger] 8.70E-27 KMQ88340.1 no hits - - - - - - NA NA NA NA NA PF13966.8: zf-RVT; PF12685.9: SpoIIIAH; - HyS0141.6 HyS0141.006 543 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF09548.12: Spore_III_AB; - HyS0141.7 HyS0141.007 544 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105850732 [Hydra vulgaris] 5.40E-64 XP_012566621.1 uncharacterized protein si:dkey-31c13.1 isoform X3 Danio rerio 65.9 26 4.57E-11 35.965 XP_009289802 NA NA NA NA NA PF15299.8: ALS2CR8; - HyS0141.11 HyS0141.011 545 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein CGI_10028156 [Crassostrea gigas] 2.90E-05 EKC41976.1 no hits - - - - - - NA NA NA NA NA - - HyS0141.13 HyS0141.013 546 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF00069.27: Pkinase; PF07714.19: PK_Tyr_Ser-Thr; - HyS0141.14 HyS0141.014 547 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF17726.3: DpnI_C; - HyS0141.15 HyS0141.015 548 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: CBL-interacting protein kinase 26-like [Hydra vulgaris] 5.40E-33 XP_012560899.1 receptor-interacting serine/threonine-protein kinase 1 Mus musculus 62 46 3.83E-09 25.882 NP_001346926 NA NA NA NA NA PF00069.27: Pkinase; PF07714.19: PK_Tyr_Ser-Thr; PF14531.8: Kinase-like; PF08155.13: NOGCT; - HyS0141.16 HyS0141.016 549 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC103909690 [Danio rerio] 2.50E-56 XP_017209257.1 uncharacterized protein LOC103909690 Danio rerio 197 63 2.53E-51 34.024 XP_017209257 SET domain-containing protein NA NA NA NA PF00856.30: SET; PF12142.10: PPO1_DWL; - HyS0148.6 HyS0148.006 550 - sex-linked-abnormal - - - 0 0.146263 0 0 0 0 0 0 0.03656575 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 Gypsy retrotransposon integrase-like protein 1 [Exaiptasia pallida] 3.40E-17 KXJ22143.1 no hits - - - - - - NA NA NA NA NA - - HyS0148.9 HyS0148.009 551 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein BSL78_19926 [Apostichopus japonicus] 1.90E-15 PIK43235.1 no hits - - - - - - NA NA NA NA NA PF05485.14: THAP; - HyS0150.3 HyS0150.003 552 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: N-lysine methyltransferase SETD8-like [Sinocyclocheilus grahami] 2.00E-22 XP_016098999.1 SET domain-containing protein 5-like Danio rerio 124 54 2.44E-32 41.447 XP_009302434 N-lysine methyltransferase SETD8 NA methyltransferase activity methylation NA PF00856.30: SET; PF00619.23: CARD; PF04689.15: S1FA; - HyS0150.4 HyS0150.004 553 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC111058950 [Nilaparvata lugens] 6.60E-10 XP_022202229.1 no hits - - - - - - NA NA NA NA NA PF11382.10: MctB; PF15934.7: Yuri_gagarin; PF13118.8: DUF3972; - HyS0150.5 HyS0150.005 554 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0150.6 HyS0150.006 555 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF13894.8: zf-C2H2_4; PF13912.8: zf-C2H2_6; PF00096.28: zf-C2H2; PF05605.14: zf-Di19; - HyS0150.11 HyS0150.011 556 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 P2X purinoceptor 7-like [Exaiptasia pallida] 8.30E-05 XP_020911659.1 no hits - - - - - - NA NA NA NA NA PF08240.14: ADH_N; - HyS0150.12 HyS0150.012 557 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF13695.8: zf-3CxxC; - HyS0173.2 HyS0173.002 558 - sex-linked-abnormal - - - 0 0.668812 0 0 0 0 0 0 0.167203 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0173.5 HyS0173.005 559 - sex-linked-abnormal - - - 0.46717 0 0 0 0 0 0 0 0.1167925 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114526661 [Dendronephthya gigantea] 2.80E-58 XP_028404039.1 uncharacterized protein LOC101883163 Danio rerio 125 38 2.38E-30 35.829 XP_005171012 RNA-directed DNA polymerase from mobile element jockey NA RNA-directed DNA polymerase activity RNA-dependent DNA biosynthetic process NA PF13276.8: HTH_21; - HyS0173.8 HyS0173.008 560 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0173.11 HyS0173.011 561 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0222.1 HyS0222.001 562 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF13611.8: Peptidase_S76; PF08769.13: Spo0A_C; PF09406.12: DUF2004; - HyS0222.3 HyS0222.003 563 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0222.4 HyS0222.004 564 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 gastrula zinc finger protein XlCGF29.1-like [Exaiptasia pallida] 1.90E-08 XP_020897216.1 oocyte zinc finger protein XlCOF6 Danio rerio 73.9 33 8.52E-13 38.889 XP_003201060 Zinc finger protein 420 NA nucleic acid binding NA NA PF00096.28: zf-C2H2; PF13894.8: zf-C2H2_4; PF12874.9: zf-met; PF09011.12: HMG_box_2; PF12171.10: zf-C2H2_jaz; PF13912.8: zf-C2H2_6; PF00505.21: HMG_box; PF16622.7: zf-C2H2_11; PF01722.20: BolA; PF13966.8: zf-RVT; PF13465.8: zf-H2C2_2; - HyS0222.5 HyS0222.005 565 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114526596 [Dendronephthya gigantea] 7.60E-36 XP_028403993.1 uncharacterized protein LOC794385 isoform X1 Danio rerio 42.7 21 0.008 25.41 XP_005172534 NA NA NA NA NA PF08020.13: DUF1706; - HyS0222.6 HyS0222.006 566 - sex-linked-abnormal - - - 3.64565 0 0 0 0 0 0 0 0.9114125 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114541686 [Dendronephthya gigantea] 7.60E-11 XP_028417286.1 uncharacterized protein LOC101884422 Danio rerio 56.6 60 1.32E-08 37 XP_009290204 NA NA NA NA NA PF00632.27: HECT; PF12630.9: Pox_polyA_pol_N; - HyS0244.1 HyS0244.001 567 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF03522.17: SLC12; - HyS0244.3 HyS0244.003 568 - sex-linked-abnormal - - - 0 0 0.126928 0 0 0 0 0 0.031732 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "complement component C3-like protein, partial [Carukia barnesi]" 6.20E-66 ACE77071.1 C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 Danio rerio 197 55 2.55E-52 32.134 XP_003201105 Alpha-2-macroglobulin CPAMD8 endopeptidase inhibitor activity negative regulation of endopeptidase activity extracellular space PF07678.16: TED_complement; PF07677.16: A2M_recep; PF05485.14: THAP; PF04136.17: Sec34; - HyS0247.2 HyS0247.002 569 - sex-linked-abnormal - - - 0 0 0 1.54822 0 0 0 0 0.387055 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105845888 [Hydra vulgaris] 4.50E-20 XP_012559572.1 no hits - - - - - - NA NA NA NA NA - - HyS0255.1 HyS0255.001 570 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein NEMVEDRAFT_v1g224657 [Nematostella vectensis] 4.80E-55 XP_001618956.1 no hits - - - - - - NA NA NA NA NA - - HyS0255.3 HyS0255.003 571 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0259.1 HyS0259.001 572 - sex-linked-abnormal - - - 0 0 0.386353 0 0 0 0 0 0.09658825 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: uncharacterized protein LOC105850374, partial [Hydra vulgaris]" 6.20E-46 XP_012566303.1 uncharacterized protein si:ch73-269m14.4 isoform X22 Danio rerio 59.7 78 5.19E-09 27.32 XP_021324935 C2H2-type domain-containing protein NA nucleic acid binding NA NA - - HyS0291.3 HyS0291.003 573 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF18072.3: FGAR-AT_linker; - HyS0328.1 HyS0328.001 574 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF13408.8: Zn_ribbon_recom; PF07191.14: zinc-ribbons_6; - HyS0426.1 HyS0426.001 575 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF15006.8: DUF4517; - HyS0473.2 HyS0473.002 576 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0611.1 HyS0611.001 577 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: 52 kDa repressor of the inhibitor of the protein kinase-like [Hydra vulgaris] 1.30E-05 XP_004209791.1 no hits - - - - - - NA NA NA NA NA - - HyS0611.2 HyS0611.002 578 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS1555.1 HyS1555.001 579 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF00428.21: Ribosomal_60s; - HyS2005.1 HyS2005.001 580 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: von Willebrand factor D and EGF domain-containing protein-like, partial [Hydra vulgaris]" 7.30E-90 XP_012555527.1 von Willebrand factor D and EGF domain-containing protein Danio rerio 191 69 1.88E-48 24.513 XP_001345360 NA NA NA NA NA PF00094.27: VWD; PF01400.26: Astacin; PF06119.16: NIDO; - HyS3563.1 HyS3563.001 581 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE18331 [Exaiptasia pallida] 1.20E-18 KXJ19517.1 zinc finger protein 687 isoform X1 Homo sapiens 40.4 63 0.004 23.469 XP_005245423 NA NA NA NA NA PF02037.29: SAP; PF13894.8: zf-C2H2_4; PF12874.9: zf-met; PF15913.7: Furin-like_2; PF18912.2: DZR_2; - HyS4663.1 HyS4663.001 582 - sex-linked-abnormal - - - 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: uncharacterized protein LOC105843862, partial [Hydra vulgaris]" 2.00E-81 XP_012555213.1 protein DBF4 homolog B isoform 2 Homo sapiens 60.5 13 6.67E-08 25.157 NP_079380 NA NA NA NA NA PF07535.14: zf-DBF; PF10740.11: DUF2529; PF02899.19: Phage_int_SAM_1; - HyS0007.309 HyS0007.309 583 - - 4 yes - 11.8966 0 0 0 0 0 0 0 2.97415 0 0 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 brachyury 2 [Dynamena pumila] 3.10E-14 QBC65504.1 T-box-containing protein TBXT-like Danio rerio 77.8 70 2.62E-18 70.833 XP_021329724 T-box transcription factor Tb TBX19 DNA-binding transcription factor activity pituitary gland development nucleus PF00907.24: T-box; - HyS0057.54 HyS0057.054 584 - - 4 yes - 2.06221 1.38456 1.4765 1.37715 0 0 0 0 1.575105 0 0 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 fibroblast growth factor receptor homolog 1-like isoform X3 [Diabrotica virgifera virgifera] 7.10E-22 XP_028138345.1 fibroblast growth factor receptor 3 isoform 1 precursor Homo sapiens 108 55 2.12E-27 66.667 NP_000133 Receptor protein-tyrosine kinase NA protein tyrosine kinase activity peptidyl-tyrosine phosphorylation focal adhesion PF07714.19: PK_Tyr_Ser-Thr; PF00069.27: Pkinase; - HyS0057.56 HyS0057.056 585 - - 4 yes - 7.43755 3.26988 0.535888 0.505216 0 0 0 0 2.9371335 0 0 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 contactin-associated protein-like 2 [Lingula anatina] 8.70E-19 XP_013389174.1 "neurexin IV, isoform A " Drosophila melanogaster 82 45 7.54E-16 33.117 NP_524034 NA NA NA NA NA PF00024.28: PAN_1; PF05033.18: Pre-SET; PF08276.13: PAN_2; - HyS0057.79 HyS0057.079 586 - - 4 yes - 0 0 0 31.4154 0 0 0 0 7.85385 0 0 1 0 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: microsomal glutathione S-transferase 2-like [Hydra vulgaris] 2.80E-41 XP_002154468.2 microsomal glutathione S-transferase 2 isoform 1 precursor Homo sapiens 114 87 1.56E-32 57.447 NP_001191295 Glutathione S-transferase theta MGST2 enzyme activator activity leukotriene metabolic process intracellular membrane-bounded organelle PF01124.20: MAPEG; - HyS0007.407 HyS0007.407 587 - - 4 yes - 28.0374 18.8215 25.1532 15.6767 1.93437 3.44573 2.35103 3.02185 21.9222 2.69005 2.68644 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 "PREDICTED: uncharacterized protein LOC105843327, partial [Hydra vulgaris]" 6.70E-42 XP_012554013.1 no hits - - - - - - NA NA NA NA NA PF05473.14: UL45; PF13196.8: DUF4012; - HyS0007.308 HyS0007.308 588 - - 4 yes - 1.13059 2.28909 2.43938 0.764124 0 0.357029 0.325869 0 1.655796 0.1785145 0.1629345 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF19071.2: DUF5767; PF13308.8: YARHG; PF02186.17: TFIIE_beta; PF17347.4: DUF5377; PF07319.13: DnaI_N; - HyS0150.7 HyS0150.007 589 - sex-linked-abnormal - - - 0 0 0 0 0.0325182 0 0 0 0 0.0162591 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC106912169 isoform X1 [Poecilia mexicana] 1.40E-49 XP_014834493.1 uncharacterized mitochondrial protein AtMg00810-like Glycine max 62 16 1.48E-08 24.725 XP_014629723 NA NA NA NA NA PF07727.16: RVT_2; PF14223.8: Retrotran_gag_2; - HyS0007.258 HyS0007.258 590 - - 4 yes - 1.28873 0 0.926163 5.21533 0.429323 1.01722 1.11579 0.294742 1.85755575 0.7232715 0.705266 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF17045.7: CEP63; PF02050.18: FliJ; PF14661.8: HAUS6_N; PF06082.13: YjbH; PF16454.7: PI3K_P85_iSH2; - HyS0070.90 HyS0070.090 591 - sex-linked-abnormal - - - 0 0 0 0 0.045514 0 0 0 0 0.022757 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: uncharacterized protein LOC105850374, partial [Hydra vulgaris]" 1.90E-59 XP_012566303.1 no hits - - - - - - NA NA NA NA NA - - HyS0067.77 HyS0067.077 592 - sex-linked-abnormal 4 yes - 0.386064 0 0.139317 0.263475 0.0643146 0 0 0 0.197214 0.0321573 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110246272 [Exaiptasia pallida] 1.10E-21 XP_020908250.1 E3 ubiquitin-protein ligase TRIM71 Mus musculus 100 45 8.87E-21 29.699 NP_001035968 NA NA NA NA NA PF01436.23: NHL; PF01731.22: Arylesterase; PF15869.7: TolB_like; PF06739.13: SBBP; - HyS4711.1 HyS4711.001 593 - sex-linked-abnormal - - - 1.19407 0 0.14376 0 0.0663075 0 0 0 0.3344575 0.03315375 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein BOX15_Mlig021084g2 [Macrostomum lignano] 9.70E-112 PAA70689.1 hypothetical protein DDB_G0282753 Dictyostelium discoideum AX4 135 29 1.03E-30 27.796 XP_640015 Reverse transcriptase domain-containing protein NA serine-type endopeptidase activity proteolysis NA PF00078.29: RVT_1; PF13966.8: zf-RVT; PF18387.3: zf_C2H2_ZHX; PF19561.1: DUF6083; - HyS0150.10 HyS0150.010 594 - sex-linked-abnormal - - - 0.693126 0 0 0 0.115467 0.109484 0 0.157829 0.1732815 0.1124755 0.0789145 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114537410 [Dendronephthya gigantea] 1.10E-35 XP_028414266.1 uncharacterized protein si:zfos-128g4.1 Danio rerio 51.6 68 3.34E-06 24.096 XP_002661969 NA NA NA NA NA PF10545.11: MADF_DNA_bdg; PF02944.22: BESS; PF00856.30: SET; - HyS0057.128 HyS0057.128 595 - - 4 yes - 12.0883 12.1399 12.3051 4.71137 1.22266 2.59194 1.48479 2.25672 10.3111675 1.9073 1.870755 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: GRB2-associated-binding protein 2 isoform X1 [Dinoponera quadriceps] 2.10E-08 XP_014467730.1 GRB2-associated-binding protein 2 isoform 1 Mus musculus 60.5 43 2.62E-08 29.858 NP_034378 NA NA NA NA NA PF00169.31: PH; - HyS0069.84 HyS0069.084 596 - sex-linked-abnormal - - - 0 0 0.267944 0 0.247802 0 0 0.169421 0.066986 0.123901 0.0847105 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF14920.8: MTBP_C; - HyS0148.5 HyS0148.005 597 - sex-linked-abnormal - - - 0 0.328342 0 0 0.0807508 0 0 0 0.0820855 0.0403754 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein PROFUN_16283 [Planoprotostelium fungivorum] 1.20E-10 PRP74337.1 Tyrosine-protein kinase Caenorhabditis elegans 61.2 44 9.91E-09 27.65 NP_501309 NA NA NA NA NA PF07714.19: PK_Tyr_Ser-Thr; PF00069.27: Pkinase; PF01636.25: APH; PF19974.1: TCAD9; PF06293.16: Kdo; PF10707.11: YrbL-PhoP_reg; PF01633.22: Choline_kinase; PF00430.20: ATP-synt_B; - HyS0007.391 HyS0007.391 598 - - 4 yes - 0 0 0 0 0 0.0828008 0 0 0 0.0414004 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene11748 [Stylophora pistillata] 6.40E-09 PFX23703.1 no hits - - - - - - NA NA NA NA NA PF13472.8: Lipase_GDSL_2; PF17182.6: OSK; PF00657.24: Lipase_GDSL; - HyS0120.25 HyS0120.025 599 - sex-linked-abnormal 4 yes - 0 0 0 0 0.0426247 0.0404303 0 0 0 0.0415275 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 Calcium-responsive transcription factor [Exaiptasia pallida] 4.30E-78 KXJ21728.1 uncharacterized protein LOC100006562 Danio rerio 47.8 15 4.36E-05 31.2 XP_021331054 NA NA NA NA NA PF00628.31: PHD; PF02902.21: Peptidase_C48; PF10551.11: MULE; PF16866.7: PHD_4; PF04434.19: SWIM; PF13831.8: PHD_2; - HyS4676.1 HyS4676.001 600 - sex-linked-abnormal - - - 2.19149 0 1.18535 0 0 0.0865509 0 0 0.84421 0.04327545 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - histone-lysine N-methyltransferase EHMT1 isoform X31 Mus musculus 79 25 2.90E-14 43.564 XP_030108085 NA NA NA NA NA PF13637.8: Ank_4; PF12796.9: Ank_2; PF13857.8: Ank_5; PF00023.32: Ank; PF13606.8: Ank_3; PF00643.26: zf-B_box; PF17675.3: APG6_N; - HyS0007.402 HyS0007.402 601 - - 4 yes - 0 0 0.75811 0 0.0875509 0 0 0 0.1895275 0.04377545 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: lysM and putative peptidoglycan-binding domain-containing protein 3-like isoform X1 [Hydra vulgaris] 2.10E-15 XP_012558672.1 lysM and putative peptidoglycan-binding domain-containing protein 4 isoform X3 Homo sapiens 59.3 21 9.54E-09 36.264 XP_011519544 NA NA NA NA NA PF01476.22: LysM; PF06195.15: DUF996; PF11322.10: DUF3124; PF12822.9: ECF_trnsprt; PF09605.12: Trep_Strep; - HyS0069.23 HyS0069.023 602 - sex-linked-abnormal - - - 0 0 0.2278 0 0.105283 0 0 0 0.05695 0.0526415 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105440338 [Strongylocentrotus purpuratus] 3.70E-13 XP_011668645.1 casein kinase like 13 Arabidopsis thaliana 60.1 54 1.46E-08 28.571 NP_171939 NA NA NA NA NA PF00069.27: Pkinase; PF07714.19: PK_Tyr_Ser-Thr; PF03109.18: ABC1; PF06293.16: Kdo; PF01636.25: APH; PF19974.1: TCAD9; PF12330.10: Haspin_kinase; - HyS0067.8 HyS0067.008 603 - sex-linked-abnormal 4 yes - 0 0 0 0.438448 0.107388 0 0 0 0.109612 0.053694 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene11834 [Stylophora pistillata] 1.00E-28 PFX23604.1 uncharacterized protein LOC108191355 Danio rerio 47.8 42 1.69E-04 25 XP_021334462 NA NA NA NA NA PF03564.17: DUF1759; - HyS0007.285 HyS0007.285 604 - - 4 yes - 0 0.223318 0 0 0.109952 0 0 0 0.0558295 0.054976 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 amiloride-sensitive sodium channel subunit beta-2-like [Exaiptasia pallida] 7.80E-21 XP_020892112.1 Uncharacterized protein CELE_C24G7.4 Caenorhabditis elegans 69.3 55 1.75E-11 28.194 NP_001309477 NA NA NA NA NA PF00858.26: ASC; PF02939.18: UcrQ; - HyS0116.22 HyS0116.022 605 - sex-linked-abnormal 4 yes - 0 0 0.821921 0 0.764884 1.08673 0.668626 1.05891 0.20548025 0.925807 0.863768 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE20058 [Exaiptasia pallida] 1.30E-22 KXJ17961.1 no hits - - - - - - NA NA NA NA NA - - HyS0291.2 HyS0291.002 606 - sex-linked-abnormal - - - 0 0 0 0 0.397568 0 0 0.272735 0 0.198784 0.1363675 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC112594324 [Melanaphis sacchari] 4.00E-07 XP_025194839.1 no hits - - - - - - NA NA NA NA NA - - HyS0120.20 HyS0120.020 607 - sex-linked-abnormal 4 yes - 0 0 0 0 0 1.73489 1.60775 0 0 0.867445 0.803875 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "hypothetical protein SELMODRAFT_86606, partial [Selaginella moellendorffii]" 9.10E-04 EFJ31707.1 krev interaction trapped protein 1 isoform 2 Mus musculus 62 86 6.34E-11 28.704 NP_001164023 Ankyrin NA ribonuclease III activity "RNA phosphodiester bond hydrolysis, endonucleolytic" NA PF12796.9: Ank_2; PF13857.8: Ank_5; PF13606.8: Ank_3; PF13637.8: Ank_4; PF00023.32: Ank; - HyS0057.78 HyS0057.078 608 - - 4 yes - 0 0 0.296133 0 0.0683616 0.0648342 0 0 0.07403325 0.0665979 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene5150 [Stylophora pistillata] 1.30E-19 PFX30044.1 uncharacterized protein LOC101886616 Danio rerio 55.1 40 1.91E-06 25.692 XP_021325228 NA NA NA NA NA PF03564.17: DUF1759; - HyS0177.5 HyS0177.005 609 - sex-linked-abnormal 4 yes - 0 1.17237 0.249764 0.471137 0.115467 0.218968 0.199071 0 0.47331775 0.1672175 0.0995355 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: zinc finger SWIM domain-containing protein 1-like [Hydra vulgaris] 7.80E-10 XP_012558607.1 no hits - - - - - - NA NA NA NA NA PF02902.21: Peptidase_C48; PF08679.13: DsrD; - HyS0070.91 HyS0070.091 610 - sex-linked-abnormal - - - 0.822838 0 0 0 0.137075 0 0 0 0.2057095 0.0685375 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF09730.11: BicD; PF19220.2: Crescentin; PF06818.17: Fez1; PF05622.14: HOOK; PF08614.13: ATG16; PF13738.8: Pyr_redox_3; PF15934.7: Yuri_gagarin; PF05531.14: NPV_P10; PF13256.8: DUF4047; PF13851.8: GAS; PF05266.16: DUF724; PF17675.3: APG6_N; - HyS0067.7 HyS0067.007 611 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0.138809 0 0 0 0.0694045 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF07516.15: SecA_SW; PF17840.3: Tugs; - HyS0173.4 HyS0173.004 612 - sex-linked-abnormal - - - 0 0 0 0 0.142531 0 0 0 0 0.0712655 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.319 HyS0007.319 613 - - 4 yes - 0.770411 1.56303 1.38756 1.04628 0.128341 0.243368 0.221407 0 1.19182025 0.1858545 0.1107035 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF19071.2: DUF5767; PF02186.17: TFIIE_beta; PF14966.8: DNA_repr_REX1B; PF19673.1: DUF6176; PF07319.13: DnaI_N; - HyS0070.24 HyS0070.024 614 - sex-linked-abnormal - - - 4.06671 6.82699 2.18407 5.43349 0 0.641216 0 0.467531 4.627815 0.320608 0.2337655 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF18627.3: PgdA_N; - HyS0148.4 HyS0148.004 615 - sex-linked-abnormal - - - 0 0.379313 0 0 0.187241 0 0 0 0.09482825 0.0936205 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0113.1 HyS0113.001 616 - sex-linked-abnormal 4 yes - 0 0.815086 0.434331 0 0 0.19076 0 0 0.31235425 0.09538 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF11812.10: DUF3333; - HyS0141.3 HyS0141.003 617 - sex-linked-abnormal - - - 1.27179 0.857636 0.914062 0.857983 0 0.200775 0 0 0.97536775 0.1003875 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC108238585 [Kryptolebias marmoratus] 2.00E-24 XP_017276271.2 uncharacterized protein si:ch211-174j14.2 Danio rerio 52.4 56 6.36E-07 28.333 XP_002662443 NA NA NA NA NA PF13837.8: Myb_DNA-bind_4; PF08822.13: DUF1804; PF00249.33: Myb_DNA-binding; PF10545.11: MADF_DNA_bdg; PF13921.8: Myb_DNA-bind_6; PF04504.16: DUF573; - HyS0150.9 HyS0150.009 618 - sex-linked-abnormal - - - 0 0.432347 0.690554 0.653356 0.10623 0.100756 0 0 0.44406425 0.103493 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: gamma-glutamyltranspeptidase 1-like [Hydra vulgaris] 2.90E-177 XP_012556244.1 gamma-glutamyltranspeptidase 1 isoform X1 Danio rerio 423 99 4.48E-140 40.306 XP_017212782 Gamma-glutamyl transpeptidase GGT1 glutathione hydrolase activity glutathione catabolic process vesicle PF01019.23: G_glu_transpept; PF08776.13: VASP_tetra; - HyS0422.5 HyS0422.005 619 - sex-linked-abnormal 4 yes - 0 0 0.451137 0 0.209095 0 0 0 0.11278425 0.1045475 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF12420.10: DUF3671; - HyS0007.301 HyS0007.301 620 - - 4 yes - 0 0.230364 0 0 0 0.215117 0 0 0.057591 0.1075585 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: kelch-like protein 2 [Hydra vulgaris] 3.30E-109 XP_012555886.1 kelch-like protein 20 isoform X4 Homo sapiens 206 91 2.56E-60 35.161 XP_011507722 BTB domain-containing protein NA DNA binding NA nucleus PF07707.17: BACK; PF00651.33: BTB; PF01344.27: Kelch_1; PF13964.8: Kelch_6; PF13415.8: Kelch_3; PF13418.8: Kelch_4; - HyS0070.119 HyS0070.119 621 - sex-linked-abnormal - - - 0 0 0 0 0.111473 0.105699 0 0 0 0.108586 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 reverse transcriptase [Lasius niger] 9.80E-24 KMQ88340.1 no hits - - - - - - NA NA NA NA NA PF13966.8: zf-RVT; - HyS0007.304 HyS0007.304 622 - - 4 yes - 11.3366 12.1269 8.50056 3.84029 0.314757 0.447582 0.54377 0 8.9510875 0.3811695 0.271885 1 0 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: zinc finger C4H2 domain-containing protein-like [Aplysia californica] 8.70E-10 XP_005090612.1 zinc finger C4H2 domain-containing protein Danio rerio 67.8 91 1.57E-12 27.488 NP_955936 NA NA NA NA NA PF10146.11: zf-C4H2; PF12773.9: DZR; PF13920.8: zf-C3HC4_3; PF13248.8: zf-ribbon_3; - HyS0291.1 HyS0291.001 623 - sex-linked-abnormal - - - 0 0 0 0 0 0.229367 0 0 0 0.1146835 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE3795 [Exaiptasia pallida] 7.50E-26 KXJ18663.1 uncharacterized protein si:ch73-7i4.2 Danio rerio 88.2 75 2.88E-19 30.405 XP_002663431 NA NA NA NA NA PF18758.3: KDZ; - HyS0116.8 HyS0116.008 624 - sex-linked-abnormal 4 yes - 0 0.857636 1.37109 0 0.211842 0.602324 0 0.581661 0.5571815 0.407083 0.2908305 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105844462 [Hydra vulgaris] 6.90E-41 XP_012556571.1 no hits - - - - - - NA NA NA NA NA PF18524.3: HPIP_like; - HyS0069.46 HyS0069.046 625 - sex-linked-abnormal - - - 0 0 0.525716 0 0.243873 0 0 0 0.131429 0.1219365 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS3583.1 HyS3583.001 626 - sex-linked-abnormal - - - 41.4936 29.8873 28.9795 24.6213 10.3196 15.9728 11.8133 14.2327 31.245425 13.1462 13.023 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: zinc finger RNA-binding protein-like [Hydra vulgaris] 5.00E-245 XP_002153846.1 "Zinc-finger protein at 72D, isoform F " Drosophila melanogaster 507 86 4.43E-165 39.094 NP_001261924 LOW QUALITY PROTEIN: zinc finger RNA-binding protein 2 ZFR zinc ion binding peptidyl-tyrosine phosphorylation nucleus PF07528.16: DZF; PF12874.9: zf-met; PF12171.10: zf-C2H2_jaz; PF11931.10: SF3a60_Prp9_C; PF12756.9: zf-C2H2_2; PF13894.8: zf-C2H2_4; PF19088.2: TUTase; - HyS0120.9 HyS0120.009 627 - sex-linked-abnormal 4 yes - 0.664688 0.225316 0.119962 0 0.0553655 0.210048 0 0 0.2524915 0.13270675 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: gamma-glutamyltranspeptidase 1-like [Hydra vulgaris] 2.30E-172 XP_012556244.1 gamma-glutamyltranspeptidase 1 isoform X1 Danio rerio 409 90 6.04E-134 39.28 XP_017212782 Gamma-glutamyltranspeptidase NA glutathione hydrolase activity glutathione catabolic process integral component of membrane PF01019.23: G_glu_transpept; PF08776.13: VASP_tetra; - HyS0116.11 HyS0116.011 628 - sex-linked-abnormal 4 yes - 0 0 0 0 0 0.282224 0 0 0 0.141112 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein K02A2.6-like [Dendronephthya gigantea] 1.40E-07 XP_028414242.1 uncharacterized protein K02A2.6 Danio rerio 45.4 71 8.77E-05 29.167 XP_005158326 NA NA NA NA NA PF00098.25: zf-CCHC; PF12773.9: DZR; PF13975.8: gag-asp_proteas; PF13650.8: Asp_protease_2; PF18912.2: DZR_2; - HyS0069.50 HyS0069.050 629 - sex-linked-abnormal - - - 0 0 0.618671 0 0.287287 0 0 0 0.15466775 0.1436435 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF09548.12: Spore_III_AB; PF02944.22: BESS; - HyS0057.57 HyS0057.057 630 - - 4 yes - 0 0 0.341128 0 0 0.299362 0 0 0.085282 0.149681 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein pdam_00018232 [Pocillopora damicornis] 2.00E-29 RMX56218.1 zinc metalloproteinase nas-4-like isoform X2 Danio rerio 126 75 1.79E-34 35.859 XP_017213608 Zinc metalloproteinase NA metalloendopeptidase activity proteolysis extracellular region PF01400.26: Astacin; PF14891.8: Peptidase_M91; PF00413.26: Peptidase_M10; - HyS4701.1 HyS4701.001 631 - X_Z - - - 6.01845 4.27773 10.4143 8.60116 0.802087 1.0458 0.863634 0.684761 7.32791 0.9239435 0.7741975 1 0 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0148.7 HyS0148.007 632 - sex-linked-abnormal - - - 33.6567 27.1347 33.3437 23.5894 1.97425 6.89001 4.34901 4.20297 29.431125 4.43213 4.27599 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: gamma-glutamyltranspeptidase 1-like [Hydra vulgaris] 1.60E-58 XP_012556244.1 gamma-glutamyltranspeptidase 1-like Danio rerio 150 46 2.16E-38 38.605 XP_697468 NA NA NA NA NA PF01019.23: G_glu_transpept; PF19071.2: DUF5767; PF05400.15: FliT; - HyS0067.55 HyS0067.055 633 - sex-linked-abnormal 4 yes - 0 0 0 0 0.312286 0 0 0 0 0.156143 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein A6F71_08245 [Cycloclasticus sp. symbiont of Poecilosclerida sp. M] 1.00E-12 ORU90924.1 no hits - - - - - - NA NA NA NA NA PF05585.14: DUF1758; PF09883.11: DUF2110; - HyS0120.16 HyS0120.016 634 - sex-linked-abnormal 4 yes - 0 0 0 0 0.166026 0.157385 0 0 0 0.1617055 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 ATP-dependent DNA helicase RRM3 [Exaiptasia pallida] 1.50E-29 KXJ06934.1 uncharacterized protein LOC101882679 Danio rerio 73.6 79 1.92E-13 31.527 XP_021330385 ATP-dependent DNA helicase NA DNA helicase activity telomere maintenance NA PF05970.16: PIF1; PF13604.8: AAA_30; - HyS0007.264 HyS0007.264 635 - - 4 yes - 4.34946 9.93851 9.83772 2.81794 0.266951 1.51928 0.786012 0.675342 6.7359075 0.8931155 0.730677 1 0 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 Protein jagged-1b [Acipenser ruthenus] 1.60E-04 RXM34569.1 leucine-rich repeat-containing protein 15-like Danio rerio 170 64 1.30E-42 29.668 XP_021322095 Leucine rich repeat protein (Fragment) NA G protein-coupled receptor activity cell surface receptor signaling pathway integral component of membrane PF13855.8: LRR_8; PF12799.9: LRR_4; PF13306.8: LRR_5; PF00560.35: LRR_1; PF14580.8: LRR_9; PF00008.29: EGF; PF13516.8: LRR_6; PF07974.15: EGF_2; PF12661.9: hEGF; PF01462.20: LRRNT; PF17420.4: GP17; PF07723.15: LRR_2; PF06247.13: Plasmod_Pvs28; PF12947.9: EGF_3; - HyS1555.2 HyS1555.002 636 - sex-linked-abnormal - - - 0 0 0 0 0.226339 0.107307 0 0 0 0.166823 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: lysM and putative peptidoglycan-binding domain-containing protein 3-like isoform X1 [Hydra vulgaris] 3.90E-22 XP_012558672.1 lysM and putative peptidoglycan-binding domain-containing protein 4 Danio rerio 59.7 27 6.26E-09 34.831 NP_957144 NA NA NA NA NA PF01476.22: LysM; - HyS0007.295 HyS0007.295 637 - - 4 yes - 14.7724 14.7666 10.1634 16.4358 0.559301 2.54559 0.771276 1.98737 14.03455 1.5524455 1.379323 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 RecName: Full=Ras-related protein Rab-1A 1.50E-60 Q05974.1 ras-related protein Rab-1A Danio rerio 241 86 1.08E-79 57.711 NP_001007162 Rab GTPase NA GTPase activity pre-mRNA catabolic process Golgi subcompartment PF00071.24: Ras; PF08477.15: Roc; PF00025.23: Arf; PF03193.18: RsgA_GTPase; PF04670.14: Gtr1_RagA; PF02421.20: FeoB_N; PF09439.12: SRPRB; PF01926.25: MMR_HSR1; PF00009.29: GTP_EFTU; PF13555.8: AAA_29; PF05673.15: DUF815; PF13191.8: AAA_16; PF00004.31: AAA; PF00493.25: MCM; PF05621.13: TniB; PF12775.9: AAA_7; PF07728.16: AAA_5; PF00910.24: RNA_helicase; - HyS0070.48 HyS0070.048 638 - sex-linked-abnormal - - - 0.746793 0.253089 2.29082 0.764618 0.435431 0.412975 0.320896 0.169652 1.01383 0.424203 0.245274 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110055434 [Orbicella faveolata] 8.90E-14 XP_020617482.1 uncharacterized protein Dmel_CG4766 Drosophila melanogaster 47.8 36 2.09E-04 22.967 NP_572287 NA NA NA NA NA PF03281.16: Mab-21; - HyS0440.1 HyS0440.001 639 - sex-linked-abnormal - - - 0 0.571531 0 0 0.0937477 0.266699 0 0 0.14288275 0.18022335 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF10571.11: UPF0547; - HyS0120.11 HyS0120.011 640 - sex-linked-abnormal 4 yes - 0 0.471931 0 0 0.466584 0.221083 0 0.320609 0.11798275 0.3438335 0.1603045 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 reverse transcriptase [Ciona intestinalis] 3.00E-14 BAC82589.1 no hits - - - - - - NA NA NA NA NA PF00637.22: Clathrin; PF00096.28: zf-C2H2; PF05605.14: zf-Di19; - HyS0007.275 HyS0007.275 641 - - 4 yes - 0.840717 0 0 0.570358 0.560213 0 0 0.191644 0.35276875 0.2801065 0.095822 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105845888 [Hydra vulgaris] 3.00E-26 XP_012559572.1 no hits - - - - - - NA NA NA NA NA - - HyS0244.5 HyS0244.005 642 - sex-linked-abnormal - - - 0.791197 1.20828 0.905215 0.812658 0.241646 0.166712 0 0.0299037 0.9293375 0.204179 0.01495185 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 predicted protein [Nematostella vectensis] 3.00E-290 XP_001626771.1 pappalysin-2 isoform X2 Danio rerio 802 97 0 33.526 XP_009296921 LOW QUALITY PROTEIN: pappalysin-2 PAPPA2 metallopeptidase activity proteolysis integral component of membrane PF13385.8: Laminin_G_3; PF00084.22: Sushi; PF05572.15: Peptidase_M43; PF02210.26: Laminin_G_2; PF08980.12: DUF1883; - HyS0057.118 HyS0057.118 643 - - 4 yes - 0 0.400099 1.27917 0 0.197566 0.187257 0 0 0.41981725 0.1924115 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105848930 [Hydra vulgaris] 1.20E-06 XP_012564632.1 E3 ubiquitin-protein ligase TRIM31 isoform X3 Homo sapiens 48.1 58 1.68E-05 29.605 XP_011512568 RING-type domain-containing protein (Fragment) NA metal ion binding NA NA PF13445.8: zf-RING_UBOX; PF13923.8: zf-C3HC4_2; PF15227.8: zf-C3HC4_4; PF00097.27: zf-C3HC4; PF14835.8: zf-RING_6; PF13639.8: zf-RING_2; PF13878.8: zf-C2H2_3; PF02891.22: zf-MIZ; PF14634.8: zf-RING_5; PF19020.2: Ta1207; PF11789.10: zf-Nse; PF00301.22: Rubredoxin; PF05207.15: zf-CSL; PF18073.3: Rubredoxin_2; PF13717.8: zinc_ribbon_4; - HyS0141.12 HyS0141.012 644 - sex-linked-abnormal - - - 0 0 0 0 0.422277 0 0 0 0 0.2111385 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0620.4 HyS0620.004 645 - sex-linked-abnormal 4 yes - 1.26901 0.427887 0.456038 0 0.422758 0 0 0 0.53823375 0.211379 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0422.6 HyS0422.006 646 - sex-linked-abnormal 4 yes - 0 0 0 0 0.815513 0.515455 0.703696 0.185953 0 0.665484 0.4448245 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 reverse transcriptase [Lasius niger] 7.00E-31 KMQ88340.1 no hits - - - - - - NA NA NA NA NA PF13966.8: zf-RVT; PF04488.17: Gly_transf_sug; - HyS0113.19 HyS0113.019 647 - sex-linked-abnormal 4 yes - 1.65298 5.59632 3.9736 1.12567 0.18358 1.04452 0.158068 0.626671 3.0871425 0.61405 0.3923695 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - adapter molecule crk isoform 3 Mus musculus 44.7 12 6.96E-05 43.75 NP_001264150 NA NA NA NA NA PF00017.26: SH2; - HyS0070.120 HyS0070.120 648 - sex-linked-abnormal - - - 0.895179 0.30248 0 0.606875 0.447377 0 0 0 0.4511335 0.2236885 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114542636 [Dendronephthya gigantea] 1.70E-07 XP_028417942.1 no hits - - - - - - NA NA NA NA NA - - HyS0328.3 HyS0328.003 649 - sex-linked-abnormal - - - 0 0 0 0 0 0.47291 0 0 0 0.236455 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0120.18 HyS0120.018 650 - sex-linked-abnormal 4 yes - 0 1.58114 0.842508 0.791467 0.390349 0.369984 0 0.267737 0.80377875 0.3801665 0.1338685 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF17315.4: FMP23; PF04778.14: LMP; - HyS0113.21 HyS0113.021 651 - sex-linked-abnormal 4 yes - 0 0.512406 0 1.02336 0.25345 0.240166 0 0 0.3839415 0.246808 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "uncharacterized protein LOC114530424, partial [Dendronephthya gigantea]" 1.40E-21 XP_028407844.1 uncharacterized protein LOC101887144 Danio rerio 73.2 46 3.13E-14 43.529 XP_021324207 NA NA NA NA NA PF18758.3: KDZ; - HyS0007.276 HyS0007.276 652 - - 4 yes - 0.415647 1.12664 1.64969 0 0.207728 0.328348 0 0 0.79799425 0.268038 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105845888 [Hydra vulgaris] 4.40E-43 XP_012559572.1 no hits - - - - - - Lactosylceramide NA NA NA NA PF00876.20: Innexin; PF14155.8: DUF4307; PF09382.12: RQC; - HyS0069.78 HyS0069.078 653 - sex-linked-abnormal - - - 0 0 0 0 0 0.539482 0 0 0 0.269741 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF16746.7: BAR_3; PF13774.8: Longin; - HyS0067.17 HyS0067.017 654 - sex-linked-abnormal 4 yes - 18.6146 5.0292 18.9895 5.89795 5.88624 6.23727 5.81677 5.66916 12.1328125 6.061755 5.742965 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 DNA polymerase subunit gamma-1-like [Orbicella faveolata] 1.70E-284 XP_020603181.1 DNA polymerase subunit gamma-1 isoform 1 Mus musculus 1008 97 0 45.254 NP_059490 "DNA polymerase gamma, catalytic subunit" POLG DNA-directed DNA polymerase activity DNA biosynthetic process gamma DNA polymerase complex PF18136.3: DNApol_Exo; PF00476.22: DNA_pol_A; PF01612.22: DNA_pol_A_exo1; - HyS0070.122 HyS0070.122 655 - sex-linked-abnormal - - - 0 0 0 0 0.495525 0.469738 0.285463 0 0 0.4826315 0.1427315 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 "reverse transcriptase-like protein, partial [Dinothrombium tinctorium]" 2.10E-04 RWR98849.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.388 HyS0007.388 656 - - 4 yes - 0.322914 0.547336 2.2147 0.441121 0.537945 0.969424 0.277398 0.513313 0.88151775 0.7536845 0.3953555 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: gamma-tubulin complex component 4-like [Hydra vulgaris] 4.90E-226 XP_004206016.1 gamma-tubulin complex component 4 isoform b Homo sapiens 546 100 0 43.982 NP_055259 Gamma-tubulin complex component TUBGCP4 gamma-tubulin binding microtubule nucleation spindle pole PF17681.3: GCP_N_terminal; PF04130.15: GCP_C_terminal; PF16669.7: TTC5_OB; - HyS0007.378 HyS0007.378 657 - - 4 yes - 8.63921 9.66838 15.328 5.8745 0.774952 2.51937 1.33575 1.21033 9.8775225 1.647161 1.27304 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: uncharacterized protein LOC105846713 [Hydra vulgaris] 1.00E-41 XP_012561173.1 Uncharacterized protein CELE_F01D5.1 Caenorhabditis elegans 54.3 44 1.63E-07 25.61 NP_496932 NA NA NA NA NA PF01549.26: ShK; - HyS0069.63 HyS0069.063 658 - sex-linked-abnormal - - - 1.10106 1.1195 1.19211 0.250542 0.427996 0.521905 0.105134 0.0833737 0.915803 0.4749505 0.09425385 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: gamma-glutamyltranspeptidase 1-like [Hydra vulgaris] 1.90E-176 XP_012556244.1 gamma-glutamyltranspeptidase 1 isoform X1 Danio rerio 418 99 2.25E-138 39.966 XP_017212782 Gamma-glutamyltranspeptidase GGT1 glutathione hydrolase activity glutathione catabolic process integral component of membrane PF01019.23: G_glu_transpept; PF08776.13: VASP_tetra; - HyS0067.64 HyS0067.064 659 - sex-linked-abnormal 4 yes - 0 0 0.337832 0 0.469081 0.296459 0 0 0.084458 0.38277 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 reverse transcriptase [Lasius niger] 5.00E-20 KMQ90064.1 hypothetical protein DDB_G0270650 Dictyostelium discoideum AX4 51.2 45 3.22E-06 32.773 XP_646304 NA NA NA NA NA PF00078.29: RVT_1; PF13276.8: HTH_21; - HyS0007.311 HyS0007.311 660 - - 4 yes - 2.74182 1.38593 1.47725 0.923663 0.685014 1.51475 0.791825 0.627452 1.63216575 1.099882 0.7096385 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 brachyury 2 [Dynamena pumila] 1.20E-71 QBC65504.1 brachyury protein isoform X2 Danio rerio 235 77 1.80E-75 69.737 XP_009305355 Brachyury transcription factor NA DNA-binding transcription factor activity "regulation of transcription, DNA-templated" nucleus PF00907.24: T-box; - HyS0070.40 HyS0070.040 661 - sex-linked-abnormal - - - 13.3249 16.2095 29.1027 43.9667 19.9779 17.3966 19.1654 17.4209 25.65095 18.68725 18.29315 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100200582 [Hydra vulgaris] 3.40E-49 XP_002154885.1 MULTISPECIES: NAD(P)H-dependent oxidoreductase Streptomyces 65.9 84 5.65E-12 29.146 WP_003976326 NA NA NA NA NA PF03358.17: FMN_red; PF02525.19: Flavodoxin_2; PF18030.3: Rimk_N; - HyS0141.9 HyS0141.009 662 - sex-linked-abnormal - - - 5.55555 0.749967 0 3.0046 0.740365 0.350886 0 0.253785 2.32752925 0.5456255 0.1268925 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - uncharacterized protein K02A2.6-like Danio rerio 42.4 33 0.003 34.667 XP_005173220 NA NA NA NA NA - - HyS0007.410 HyS0007.410 663 - - 4 yes - 2.30989 1.79228 3.3092 1.97841 1.29186 1.27767 0.565847 1.14077 2.347445 1.284765 0.8533085 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: dmX-like protein 1 [Hydra vulgaris] 0 XP_012558581.1 dmX-like protein 1 Mus musculus 1073 99 0 31.072 NP_001074840 DmX protein 2 DMXL1 NA vacuolar acidification RAVE complex PF12234.10: Rav1p_C; PF00400.34: WD40; PF14761.8: HPS3_N; PF16965.7: CSG2; - HyS0069.19 HyS0069.019 664 - sex-linked-abnormal - - - 5.85709 4.9318 5.25716 0.985378 0 0.924397 0 0 4.257857 0.4621985 0 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF08074.13: CHDCT2; PF04652.18: Vta1; - HyS0069.20 HyS0069.020 665 - sex-linked-abnormal - - - 0 0 0 0 0.935619 0 0 0 0 0.4678095 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0057.1 HyS0057.001 666 - - 4 yes - 0 0 0 0 0.649686 0.307734 0 0 0 0.47871 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF12052.10: VGCC_beta4Aa_N; - HyS0177.6 HyS0177.006 667 - sex-linked-abnormal 4 yes - 0.874936 0.591347 0.315009 0.593308 0.291507 0.690907 0 0 0.59365 0.491207 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF08746.13: zf-RING-like; PF00130.24: C1_1; - HyS0007.361 HyS0007.361 668 - - 4 yes - 4.02519 7.42219 7.14355 5.98844 1.51606 1.687 1.25134 0.952792 6.1448425 1.60153 1.102066 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: uncharacterized protein LOC105846954 [Hydra vulgaris] 3.40E-177 XP_012561620.1 hypothetical protein DDB_G0284633 Dictyostelium discoideum AX4 83.2 31 1.02E-14 25.575 XP_638443 Transposable element P transposase NA transposase activity "transposition, DNA-mediated" NA PF02995.19: DUF229; PF05485.14: THAP; - HyS0057.85 HyS0057.085 669 - - 4 yes - 4.53813 7.16163 5.99428 8.21905 1.638 3.22556 1.08671 2.75691 6.4782725 2.43178 1.92181 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF08726.12: EFhand_Ca_insen; - HyS0069.16 HyS0069.016 670 - sex-linked-abnormal - - - 0 0 0 0 0.532677 0.50446 0 0 0 0.5185685 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.364 HyS0007.364 671 - - 4 yes - 4.26961 2.45911 4.31328 2.03861 1.13804 1.95624 0.978902 0.970323 3.2701525 1.54714 0.9746125 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: neuronal acetylcholine receptor subunit alpha-2-like [Hydra vulgaris] 4.20E-174 XP_004208655.2 neuronal acetylcholine receptor subunit alpha-7a Danio rerio 320 95 7.36E-103 36.961 NP_957513 Nicotinic acetylcholine receptor alpha subunit NA acetylcholine-gated cation-selective channel activity excitatory postsynaptic potential postsynaptic membrane PF02931.25: Neur_chan_LBD; PF02932.18: Neur_chan_memb; PF00335.22: Tetraspanin; - HyS0116.6 HyS0116.006 672 - sex-linked-abnormal 4 yes - 0.734043 0.870719 1.32457 0 0.611423 0.637883 0 0.0833737 0.732333 0.624653 0.04168685 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC110050835 [Orbicella faveolata] 7.10E-132 XP_020612467.1 uncharacterized protein LOC101883107 Danio rerio 260 85 2.09E-79 36.49 XP_005156758 Integrase core domain NA nucleic acid binding DNA integration integral component of membrane PF00665.28: rve; PF13384.8: HTH_23; PF06056.14: Terminase_5; PF02881.21: SRP54_N; - HyS0069.8 HyS0069.008 673 - sex-linked-abnormal - - - 1.913 1.6213 1.38111 2.39564 0.584263 0.705289 0 0.0724017 1.8277625 0.644776 0.03620085 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: gamma-glutamyltranspeptidase 1-like [Hydra vulgaris] 1.70E-174 XP_012556244.1 gamma-glutamyltranspeptidase 1 isoform X1 Danio rerio 412 99 5.57E-136 39.626 XP_017212782 Gamma-glutamyltranspeptidase GGT1 glutathione hydrolase activity glutathione catabolic process vesicle PF01019.23: G_glu_transpept; PF08776.13: VASP_tetra; - HyS0057.43 HyS0057.043 674 - - 4 yes - 1.47544 0 3.17818 0 0.73719 1.86286 0 1.35162 1.163405 1.300025 0.67581 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: voltage-gated hydrogen channel 1-like [Hydra vulgaris] 6.20E-33 XP_012554112.1 voltage-gated hydrogen channel 1 Danio rerio 121 65 4.28E-33 48.78 NP_001002346 Voltage-gated proton channel HVCN1 voltage-gated proton channel activity proton transmembrane transport integral component of plasma membrane PF00520.33: Ion_trans; PF00627.33: UBA; - HyS0057.70 HyS0057.070 675 - - 4 yes - 15.1263 13.9011 18.117 8.83055 15.6592 12.9721 14.7216 12.6561 13.9937375 14.31565 13.68885 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 peptidyl-glycine alpha-amidating monooxygenase isoform X1 [Larimichthys crocea] 1.70E-62 XP_027132605.1 peptidyl-glycine alpha-amidating monooxygenase isoform X2 Danio rerio 239 97 8.69E-70 33.987 XP_009303381 Peptidyl-glycine alpha-amidating monooxygenase B NA "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen" peptide metabolic process membrane PF03712.17: Cu2_monoox_C; PF01082.22: Cu2_monooxygen; PF01436.23: NHL; PF06739.13: SBBP; PF12680.9: SnoaL_2; - HyS0007.256 HyS0007.256 676 - - 4 yes - 5.83954 7.01424 7.55618 11.8119 1.94563 4.38303 3.13326 1.93277 8.055465 3.16433 2.533015 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 "PREDICTED: beta-1,3-galactosyltransferase sqv-2-like [Hydra vulgaris]" 3.10E-89 XP_002158539.1 "beta-1,3-galactosyltransferase 1 " Mus musculus 46.6 60 6.18E-04 24.088 NP_001366253 Hexosyltransferase NA UDP-galactosyltransferase activity protein O-linked glycosylation Golgi membrane PF01762.23: Galactosyl_T; PF15168.8: TRIQK; PF13283.8: NfrA_C; PF08635.12: ox_reductase_C; PF11556.10: EBA-175_VI; - HyS0070.125 HyS0070.125 677 - sex-linked-abnormal - - - 0 0 0 0 1.2744 0 0 0 0 0.6372 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF17315.4: FMP23; - HyS0057.77 HyS0057.077 678 - - 4 yes - 0 2.17008 0.288978 0.54461 0.801985 0.887091 0.230649 0.18285 0.750917 0.844538 0.2067495 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF12731.9: Mating_N; - HyS0069.39 HyS0069.039 679 - sex-linked-abnormal - - - 0 0.675684 0 0 0.334941 0.95187 0 0 0.168921 0.6434055 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 uncharacterized protein LOC114526114 [Dendronephthya gigantea] 2.40E-30 XP_028403417.1 uncharacterized protein LOC108180169 isoform X1 Danio rerio 40 85 0.005 27.907 XP_021323828 NA NA NA NA NA - - HyS0069.85 HyS0069.085 680 - sex-linked-abnormal - - - 3.867 1.63266 2.08749 1.30957 0.96629 0.763352 0 0.441156 2.22418 0.864821 0.220578 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AWC38_SpisGene11308 [Stylophora pistillata] 1.10E-24 PFX24096.1 no hits - - - - - - NA NA NA NA NA PF07739.15: TipAS; PF17527.4: ALC; PF04504.16: DUF573; PF13837.8: Myb_DNA-bind_4; - HyS0057.59 HyS0057.059 681 - - 4 yes - 37.7612 57.6016 37.1112 78.8753 5.83309 13.6645 6.90119 11.2556 52.837325 9.748795 9.078395 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.330 HyS0007.330 682 - - 4 yes - 17.184 38.5101 33.1755 16.1862 2.77848 3.35352 1.44938 3.33289 26.26395 3.066 2.391135 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 332-1 secreted propeptide [Malo kingi] 4.40E-20 AKU77030.1 Uncharacterized protein CELE_Y39G8B.7 Caenorhabditis elegans 42.4 36 0.002 32 NP_496930 NA NA NA NA NA PF01549.26: ShK; - HyS0057.66 HyS0057.066 683 - - 4 yes - 3.54176 14.8555 10.4645 4.81391 4.95615 7.4965 5.69715 5.32338 8.4189175 6.226325 5.510265 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 tyrosine-protein kinase RYK-like [Orbicella faveolata] 1.00E-17 XP_020629538.1 hepatocyte growth factor receptor isoform X3 Mus musculus 78.6 32 1.39E-14 37.5 XP_036021796 NA NA NA NA NA PF07714.19: PK_Tyr_Ser-Thr; PF00069.27: Pkinase; PF17424.4: DUF5411; - HyS0007.273 HyS0007.273 684 - - 4 yes - 0.732491 0.247736 1.5834 0 0.854172 0.578492 0 0 0.64090675 0.716332 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105845888 [Hydra vulgaris] 2.50E-34 XP_012559572.1 no hits - - - - - - NA NA NA NA NA - - HyS0057.31 HyS0057.031 685 - - 4 yes - 13.7192 10.5146 13.4474 5.89162 2.28523 1.77209 1.43929 1.14062 10.893205 2.02866 1.289955 1 1 1 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: uncharacterized protein LOC105843242 [Hydra vulgaris] 8.60E-15 XP_012553783.1 no hits - - - - - - NA NA NA NA NA PF05225.18: HTH_psq; PF12116.10: SpoIIID; PF02001.18: DUF134; - HyS0007.349 HyS0007.349 686 - - 4 yes - 1.25578 3.18727 4.75284 0 0.627597 1.2894 0 0.428718 2.2989725 0.9584985 0.214359 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0070.93 HyS0070.093 687 - sex-linked-abnormal - - - 0 0 0 0 1.67807 0 0 0 0 0.839035 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0069.89 HyS0069.089 688 - sex-linked-abnormal - - - 0 0 8.23695 0 0 1.8303 0 0 2.0592375 0.91515 0 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein AC249_AIPGENE26415 [Exaiptasia pallida] 7.00E-06 KXJ26841.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.305 HyS0007.305 689 - - 4 yes - 0 2.63995 2.81324 0.755425 4.654 3.5291 2.25449 4.08421 1.55215375 4.09155 3.16935 1 1 1 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: E3 ubiquitin-protein ligase NEDD4-like isoform X1 [Hydra vulgaris] 6.00E-46 XP_012560818.1 E3 ubiquitin-protein ligase NEDD4-like isoform X9 Mus musculus 149 66 8.06E-40 48.344 XP_036017211 E3 ubiquitin-protein ligase nedd-4 NEDD4 ubiquitin protein ligase activity ubiquitin-dependent protein catabolic process cytoplasm PF00168.32: C2; - HyS0057.32 HyS0057.032 690 - - 4 yes - 7.52433 0.508904 3.79483 3.57737 1.37881 1.545 0.216208 0.685634 3.8513585 1.461905 0.450921 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: carboxypeptidase B-like [Hydra vulgaris] 1.70E-59 XP_012555360.1 carboxypeptidase A2 isoform X1 Mus musculus 224 96 1.12E-70 39.803 XP_011239359 Zinc carboxypeptidase A CPA2 metallocarboxypeptidase activity proteolysis extracellular space PF00246.26: Peptidase_M14; - HyS0057.7 HyS0057.007 691 - - 4 yes - 6.91979 4.80312 6.18497 5.40117 19.9814 19.264 21.0425 16.1639 5.8272625 19.6227 18.6032 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF13424.8: TPR_12; PF13374.8: TPR_10; PF13176.8: TPR_7; PF13428.8: TPR_14; PF07719.19: TPR_2; PF14559.8: TPR_19; PF13174.8: TPR_6; PF13432.8: TPR_16; PF01535.22: PPR; PF00515.30: TPR_1; - HyS0222.2 HyS0222.002 692 - sex-linked-abnormal - - - 8.51412 5.55737 3.72693 1.65535 1.72229 1.72924 0.698183 0.691968 4.8634425 1.725765 0.6950755 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 hypothetical protein NEMVEDRAFT_v1g225312 [Nematostella vectensis] 3.50E-19 XP_001618284.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.277 HyS0007.277 693 - - 4 yes - 3.43985 3.49334 5.78774 4.68366 1.62362 1.35851 0.328998 0.521726 4.3511475 1.491065 0.425362 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: uncharacterized protein LOC105845888 [Hydra vulgaris] 6.30E-33 XP_012559572.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.320 HyS0007.320 694 - - 4 yes - 0 3.07737 9.84212 3.00716 1.53381 0.726457 0 0 3.9816625 1.1301335 0 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0067.70 HyS0067.070 695 - sex-linked-abnormal 4 yes - 7.69929 5.39955 5.75083 7.86484 35.2721 27.7143 34.0776 26.6454 6.6786275 31.4932 30.3615 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: geranylgeranyl transferase type-1 subunit beta-like [Hydra vulgaris] 1.40E-137 XP_012555341.1 geranylgeranyl transferase type-1 subunit beta Homo sapiens 431 98 5.00E-150 54.467 NP_005014 Geranylgeranyl transferase type-1 subunit beta PGGT1B protein geranylgeranyltransferase activity protein geranylgeranylation CAAX-protein geranylgeranyltransferase complex PF00432.23: Prenyltrans; PF06618.13: DUF1148; - HyS0113.32 HyS0113.032 696 - sex-linked-abnormal 4 yes - 22.6221 14.9497 16.5999 20.8449 42.3343 38.4234 46.0127 32.4632 18.75415 40.37885 39.23795 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: tRNA dimethylallyltransferase, mitochondrial-like [Hydra vulgaris]" 1.70E-107 XP_012558256.1 tRNA dimethylallyltransferase Danio rerio 349 99 7.19E-116 43.262 NP_001038239 tRNA dimethylallyltransferase TRIT1 tRNA dimethylallyltransferase activity tRNA processing cytoplasm PF01715.19: IPPT; PF01745.18: IPT; PF12171.10: zf-C2H2_jaz; PF12874.9: zf-met; PF11931.10: SF3a60_Prp9_C; PF13238.8: AAA_18; PF13671.8: AAA_33; PF07475.14: Hpr_kinase_C; - HyS0247.1 HyS0247.001 697 - sex-linked-abnormal - - - 15.9085 18.4396 9.36518 3.99825 0.976392 2.77801 0.359915 0.951367 11.9278825 1.877201 0.655641 1 1 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 no hits - - "bonus, isoform C " Drosophila melanogaster 47.8 60 1.57E-04 21.008 NP_001262765 NA NA NA NA NA PF00643.26: zf-B_box; PF08470.12: NTNH_C; PF19071.2: DUF5767; PF17279.4: DUF5344; - HyS0007.270 HyS0007.270 698 - - 4 yes - 6.93811 6.62868 8.19673 2.80057 1.94389 1.94339 0.632101 0.644518 6.1410225 1.94364 0.6383095 1 1 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: cytochrome P450 4V2-like [Hydra vulgaris] 4.70E-134 XP_012555469.1 cytochrome P450 4V2 Mus musculus 388 90 2.37E-128 42.771 NP_598730 Plasma kallikrein isoform A NA "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" fatty acid omega-oxidation integral component of membrane PF00067.24: p450; - HyS0177.3 HyS0177.003 699 - sex-linked-abnormal 4 yes - 5.44239 6.24109 5.73995 2.28471 2.02253 1.65358 0.719829 0.28541 4.927035 1.838055 0.5026195 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 PREDICTED: steroid 21-hydroxylase [Latimeria chalumnae] 2.50E-55 XP_014347016.1 "steroid 17-alpha-hydroxylase/17,20 lyase precursor " Danio rerio 209 94 5.12E-60 28.291 NP_997971 "Steroid 17-alpha-hydroxylase/17,20 lyase (Fragment)" NA "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" oxidation-reduction process NA PF00067.24: p450; - HyS0067.26 HyS0067.026 700 - sex-linked-abnormal 4 yes - 47.8913 35.9264 35.603 46.0741 121.088 123.855 143.174 98.9003 41.3737 122.4715 121.03715 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: COMM domain-containing protein 10-like [Branchiostoma belcheri] 8.70E-49 XP_019633071.1 COMM domain-containing protein 10 isoform a Homo sapiens 178 95 1.52E-55 50 NP_057228 COMM domain-containing protein 10 COMMD10 NA vesicle-mediated transport membrane coat PF07258.16: COMM_domain; PF00416.24: Ribosomal_S13; - HyS0007.331 HyS0007.331 701 - - 4 yes - 10.8822 13.0204 15.2508 11.3684 6.50502 6.67553 4.49076 5.66919 12.63045 6.590275 5.079975 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100635885 [Amphimedon queenslandica] 2.20E-70 XP_003383100.1 E3 ubiquitin-protein ligase WAV3-like Glycine max 157 91 1.09E-39 27.481 XP_003539773 Inter-alpha-trypsin inhibitor heavy chain H3 NA NA signal transduction NA PF00092.30: VWA; PF13768.8: VWA_3; PF13519.8: VWA_2; PF18117.3: EDS1_EP; PF05762.16: VWA_CoxE; - HyS0007.414 HyS0007.414 702 - - 4 yes - 10.6216 15.7435 12.0641 10.5349 24.2276 19.3567 18.5569 21.9735 12.241025 21.79215 20.2652 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: ras-related protein Rab-18-like [Hydra vulgaris] 2.50E-88 XP_002163996.1 ras-related protein Rab-18a Danio rerio 314 99 2.52E-109 76.119 NP_996661 Bromodomain-containing protein 1 RAB18 GTPase activity lipid droplet organization endoplasmic reticulum tubular network PF00071.24: Ras; PF08477.15: Roc; PF00025.23: Arf; PF01926.25: MMR_HSR1; PF00009.29: GTP_EFTU; PF03193.18: RsgA_GTPase; PF04670.14: Gtr1_RagA; PF09439.12: SRPRB; PF13479.8: AAA_24; PF13191.8: AAA_16; PF03029.19: ATP_bind_1; PF13401.8: AAA_22; PF10662.11: PduV-EutP; PF13555.8: AAA_29; PF00735.20: Septin; PF00005.29: ABC_tran; - HyS0007.310 HyS0007.310 703 - - 4 yes - 13.4883 7.20694 12.9349 6.078 7.86412 3.54958 4.53542 3.33786 9.927035 5.70685 3.93664 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 brachyury 2 [Dynamena pumila] 5.90E-86 QBC65504.1 T-box transcription factor T Mus musculus 163 94 8.16E-47 45.794 NP_033335 Brachyury transcription factor NA DNA-binding transcription factor activity "regulation of transcription, DNA-templated" nucleus PF00907.24: T-box; - HyS0070.76 HyS0070.076 704 - sex-linked-abnormal - - - 0.572498 1.10059 1.24071 2.08914 2.47971 2.47279 0.272933 0.346355 1.2507345 2.47625 0.309644 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 Uncharacterized protein YfaL [Exaiptasia pallida] 6.00E-40 KXJ29021.1 pectin lyase-like family protein Dictyostelium discoideum AX4 50.1 19 1.08E-04 24.057 XP_642282 NA NA NA NA NA PF20063.1: DUF6462; PF07699.15: Ephrin_rec_like; - HyS0007.263 HyS0007.263 705 - - 4 yes - 8.78299 5.23675 6.88811 3.3107 2.62361 3.58911 0.346841 1.16903 6.0546375 3.10636 0.7579355 1 1 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 PREDICTED: LOW QUALITY PROTEIN: chondroadherin-like protein [Taeniopygia guttata] 1.50E-09 XP_004175970.1 slit homolog 1 protein precursor Mus musculus 98.6 48 7.69E-20 29.167 NP_056563 NA NA NA NA NA PF13855.8: LRR_8; PF10545.11: MADF_DNA_bdg; PF13306.8: LRR_5; PF12799.9: LRR_4; PF07974.15: EGF_2; PF17870.3: Insulin_TMD; PF13873.8: Myb_DNA-bind_5; PF13516.8: LRR_6; PF06024.14: Orf78; PF13314.8: DUF4083; PF00560.35: LRR_1; PF02944.22: BESS; PF00008.29: EGF; - HyS0007.339 HyS0007.339 706 - - 4 yes - 6.09077 8.94306 4.98154 3.87861 11.4995 11.0345 8.02819 8.76529 5.973495 11.267 8.39674 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 transcription factor p63 [Nematostella vectensis] 1.30E-24 ABF72158.1 tumor protein p73 isoform e Homo sapiens 92.8 45 3.24E-19 32.353 NP_001191118 NA NA NA NA NA PF00870.20: P53; - HyS0007.278 HyS0007.278 707 - - 4 yes - 4.43943 7.36923 2.24224 2.72471 3.62387 3.43679 0.636236 0.504521 4.1939025 3.53033 0.5703785 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 "PREDICTED: beta-1,3-galactosyltransferase 6-like [Acropora digitifera]" 9.00E-36 XP_015756215.1 Galactosyltransferase family protein Arabidopsis thaliana 50.1 41 2.11E-05 24.841 NP_567762 NA NA NA NA NA PF01762.23: Galactosyl_T; - HyS0057.13 HyS0057.013 708 - - 4 yes - 8.78333 11.8139 7.55765 5.88848 23.1068 21.8922 16.7936 22.1723 8.51084 22.4995 19.48295 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: pyroglutamyl-peptidase 1-like isoform X1 [Hydra vulgaris] 2.90E-26 XP_002153799.3 pyroglutamyl-peptidase 1 Danio rerio 89 89 3.53E-21 37.342 NP_001018362 Pyroglutamyl-peptidase NA pyroglutamyl-peptidase activity proteolysis cytosol PF01470.19: Peptidase_C15; PF06162.14: PgaPase_1; - HyS0007.351 HyS0007.351 709 - - 4 yes - 11.9426 22.1858 20.8027 9.55242 13.172 9.56443 6.37239 9.82584 16.12088 11.368215 8.099115 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: protein FAM154A-like [Hydra vulgaris] 6.40E-37 XP_002155920.1 stabilizer of axonemal microtubules 1 Mus musculus 79.3 88 1.74E-14 23.462 NP_001074565 NA NA NA NA NA PF05217.14: STOP; - HyS0057.9 HyS0057.009 710 - - 4 yes - 27.5922 29.6978 26.7937 40.9739 51.3737 48.2101 47.3215 45.0865 31.2644 49.7919 46.204 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: mitochondrial import inner membrane translocase subunit TIM44-like [Hydra vulgaris] 2.40E-163 XP_012557910.1 mitochondrial import inner membrane translocase subunit TIM44 Danio rerio 367 89 2.96E-122 43.103 NP_001013525 Translocase of inner mitochondrial membrane 44 TIMM44 chaperone binding protein import into mitochondrial matrix mitochondrial inner membrane PF04280.17: Tim44; PF17927.3: Ins134_P3_kin_N; PF17942.3: Morc6_S5; PF11439.10: T3SchapCesA; PF16224.7: DUF4883; PF14357.8: DUF4404; - HyS0007.338 HyS0007.338 711 - - 4 yes - 12.1821 12.9915 10.4172 4.30723 14.206 14.5418 11.1226 10.3583 9.9745075 14.3739 10.74045 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 cellular tumor antigen p53-like isoform X2 [Orbicella faveolata] 9.00E-25 XP_020628162.1 tumor protein p73 isoform e Homo sapiens 95.5 54 3.04E-20 31.034 NP_001191118 NA NA NA NA NA PF00870.20: P53; PF08133.13: Nuclease_act; - HyS0057.112 HyS0057.112 712 - - 4 yes - 86.0197 105.509 49.2622 34.871 4.57339 14.1666 3.85217 6.38627 68.915475 9.369995 5.11922 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 SP5 protein [Hydra vulgaris] 4.10E-60 AXP19710.1 transcription factor Sp5 Mus musculus 214 89 5.63E-65 38.76 NP_071880 Zn-finger transcription factor NA nucleic acid binding mesoderm morphogenesis nucleus PF00096.28: zf-C2H2; PF13465.8: zf-H2C2_2; PF13894.8: zf-C2H2_4; PF13912.8: zf-C2H2_6; PF12171.10: zf-C2H2_jaz; PF12874.9: zf-met; PF15909.7: zf-C2H2_8; PF13909.8: zf-H2C2_5; PF20026.1: DUF6434; PF16622.7: zf-C2H2_11; PF17017.7: zf-C2H2_aberr; PF08790.13: zf-LYAR; - HyS0070.84 HyS0070.084 713 - sex-linked-abnormal - - - 8.70157 7.34763 9.31767 9.086 19.3223 17.8769 15.1363 12.7998 8.6132175 18.5996 13.96805 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100204624 [Hydra vulgaris] 8.70E-268 XP_012555491.1 nucleolar pre-ribosomal-associated protein 1 Homo sapiens 264 58 1.46E-69 33.117 NP_055640 Nucleolar pre-ribosomal-associated protein 1 (Fragment) NA NA NA NA PF11707.10: Npa1; PF16201.7: NopRA1; - HyS0070.57 HyS0070.057 714 - sex-linked-abnormal - - - 73.6211 114.087 51.0516 40.0716 6.23903 6.93248 1.86383 1.77242 69.707825 6.585755 1.818125 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0007.297 HyS0007.297 715 - - 4 yes - 2.92547 13.2107 12.8382 6.31395 16.8137 15.2519 9.36684 12.6378 8.82208 16.0328 11.00232 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: glycosylated lysosomal membrane protein B-like [Hydra vulgaris] 7.20E-63 XP_004206724.2 glycosylated lysosomal membrane protein precursor Danio rerio 100 86 5.34E-22 25.62 NP_001004580 Lysosomal protein NCU-G1 (Fragment) NA NA NA integral component of membrane PF15065.8: NCU-G1; - HyS0113.37 HyS0113.037 716 - sex-linked-abnormal 4 yes - 10.5701 12.0975 12.213 14.4505 25.3567 21.2117 17.0929 19.3745 12.332775 23.2842 18.2337 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: DEAD-box ATP-dependent RNA helicase 41-like [Hydra vulgaris] 1.10E-158 XP_012562420.1 probable ATP-dependent RNA helicase DDX59 Mus musculus 465 64 8.71E-154 46.304 NP_080776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 DDX59 ATP binding microtubule-based movement NA PF00270.31: DEAD; PF00271.33: Helicase_C; PF00219.20: IGFBP; PF04438.18: zf-HIT; PF14617.8: CMS1; PF06664.14: MIG-14_Wnt-bd; - HyS0113.40 HyS0113.040 717 - sex-linked-abnormal 4 yes - 72.3482 51.5169 55.7987 49.5254 49.0622 55.0843 51.1682 42.7628 57.2973 52.07325 46.9655 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: AP-3 complex subunit beta-1-like [Hydra vulgaris] 0 XP_012555888.1 AP-3 complex subunit beta-2 Mus musculus 928 59 0 67.281 NP_067467 AP-3 complex subunit beta NA GTP-dependent protein binding vesicle-mediated transport AP-3 adaptor complex PF01602.22: Adaptin_N; PF14796.8: AP3B1_C; PF12717.9: Cnd1; PF13646.8: HEAT_2; PF02985.24: HEAT; PF13513.8: HEAT_EZ; PF12054.10: DUF3535; PF08018.13: Antimicrobial_1; - HyS0007.313 HyS0007.313 718 - - 4 yes - 10.0912 9.8296 12.2882 10.6125 41.0466 32.9496 34.2205 29.5254 10.705375 36.9981 31.87295 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: ubiquitin carboxyl-terminal hydrolase 3-like [Hydra vulgaris] 3.10E-212 XP_002167244.2 ubiquitin carboxyl-terminal hydrolase 3 Danio rerio 479 96 1.69E-164 48.211 NP_001186800 Ubiquitin carboxyl-terminal hydrolase USP3 thiol-dependent ubiquitinyl hydrolase activity protein deubiquitination Flemming body PF00443.31: UCH; PF13423.8: UCH_1; PF02148.21: zf-UBP; PF01412.20: ArfGap; PF08646.12: Rep_fac-A_C; PF14369.8: zinc_ribbon_9; - HyS0116.17 HyS0116.017 719 - sex-linked-abnormal 4 yes - 3.91267 1.70307 7.65862 7.99266 7.0768 7.15234 1.60361 2.16159 5.316755 7.11457 1.8826 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 "forkhead box 2c protein, partial [Cladonema pacificum]" 4.60E-57 BAQ19161.1 forkhead domain 102C Drosophila melanogaster 175 32 5.76E-48 61.417 NP_651951 Forkhead box Q:D protein transcription NA sequence-specific DNA binding "regulation of transcription, DNA-templated" nucleus PF00250.20: Forkhead; - HyS0007.303 HyS0007.303 720 - - 4 yes - 8.79211 12.4549 10.9951 8.79449 19.3025 17.3156 12.2275 13.7614 10.25915 18.30905 12.99445 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: E3 ubiquitin-protein ligase NEDD4-like isoform X1 [Hydra vulgaris] 1.20E-246 XP_012560818.1 E3 ubiquitin-protein ligase NEDD4 isoform 3 Homo sapiens 736 92 0 60.714 NP_001271267 "Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase" NEDD4 ubiquitin-protein transferase activity protein ubiquitination dendritic spine PF00632.27: HECT; PF00397.28: WW; PF06085.13: Rz1; - HyS0067.46 HyS0067.046 721 - sex-linked-abnormal 4 yes - 5.47761 8.04463 6.72136 6.48146 24.1513 18.9825 17.0503 13.8531 6.681265 21.5669 15.4517 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3-like isoform X2 [Dendronephthya gigantea] 2.30E-04 XP_028415428.1 no hits - - - - - - NA NA NA NA NA PF00641.20: zf-RanBP; PF10224.11: DUF2205; PF05546.13: She9_MDM33; PF09602.12: PhaP_Bmeg; PF07889.14: DUF1664; PF02183.20: HALZ; PF05043.15: Mga; PF03105.21: SPX; PF19220.2: Crescentin; PF18332.3: XRN1_D1; PF09351.12: DUF1993; PF06148.13: COG2; PF16988.7: Vps36-NZF-N; PF03961.15: FapA; PF05149.14: Flagellar_rod; - HyS2552.1 HyS2552.001 722 - sex-linked-abnormal 4 yes - 19.1676 5.43805 8.59406 13.4115 23.4738 22.5061 20.0577 12.8413 11.6528025 22.98995 16.4495 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: E3 ubiquitin-protein ligase RNF220-like [Hydra vulgaris] 2.00E-66 XP_004208086.1 E3 ubiquitin-protein ligase RNF220 isoform 4 Homo sapiens 135 62 3.19E-35 32.423 NP_001363418 RING-type domain-containing protein (Fragment) RNF220 ubiquitin-protein transferase activity protein ubiquitination cytoplasm PF15926.7: RNF220; PF13923.8: zf-C3HC4_2; PF14634.8: zf-RING_5; PF13920.8: zf-C3HC4_3; PF13639.8: zf-RING_2; PF00097.27: zf-C3HC4; PF13445.8: zf-RING_UBOX; PF14835.8: zf-RING_6; PF09798.11: LCD1; PF12874.9: zf-met; PF14447.8: Prok-RING_4; - HyS0070.12 HyS0070.012 723 - sex-linked-abnormal - - - 8.66001 11.8953 10.4123 5.9028 23.8041 19.3822 12.6907 17.173 9.2176025 21.59315 14.93185 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: ceramide synthase 1-like [Hydra vulgaris] 2.00E-78 XP_012564299.1 ceramide synthase 1 Danio rerio 210 75 1.41E-63 35.836 XP_009294228 Ceramide synthase 1 CERS1 sphingosine N-acyltransferase activity ceramide biosynthetic process endoplasmic reticulum PF03798.18: TRAM_LAG1_CLN8; PF08390.13: TRAM1; - HyS0070.42 HyS0070.042 724 - sex-linked-abnormal - - - 11.1695 13.7832 11.8399 16.5321 26.5974 24.7011 18.299 19.1451 13.331175 25.64925 18.72205 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: GDP-L-fucose synthase-like [Hydra vulgaris] 1.90E-154 XP_012553654.1 GDP-L-fucose synthase Mus musculus 472 99 8.13E-168 68.354 NP_001343934 Leucine-rich repeat transmembrane neuronal protein 4 TSTA3 "GDP-mannose 3,5-epimerase activity" nucleotide-sugar biosynthetic process integral component of membrane PF01370.23: Epimerase; PF16363.7: GDP_Man_Dehyd; PF04321.19: RmlD_sub_bind; PF02719.17: Polysacc_synt_2; PF01073.21: 3Beta_HSD; PF07993.14: NAD_binding_4; - HyS0067.44 HyS0067.044 725 - sex-linked-abnormal 4 yes - 13.0373 6.3965 22.0845 16.4032 24.2164 18.9466 15.347 13.6518 14.480375 21.5815 14.4994 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 DTW domain-containing protein 2-like [Dendronephthya gigantea] 1.20E-47 XP_028411268.1 DTW domain-containing protein 2 Danio rerio 176 87 7.26E-53 42.13 XP_021324611 DTW domain-containing protein 2 NA NA somite development NA PF03942.17: DTW; - HyS0067.23 HyS0067.023 726 - sex-linked-abnormal 4 yes - 9.80008 8.30149 7.80896 12.2581 13.741 12.903 5.96739 6.49509 9.5421575 13.322 6.23124 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 dimethylaniline monooxygenase [N-oxide-forming] 5-like [Exaiptasia pallida] 1.60E-155 XP_020916685.1 flavin-containing monooxygenase 5 isoform 1 Mus musculus 503 99 1.13E-173 48.224 NP_001155235 Flavin-containing monooxygenase NA "N,N-dimethylaniline monooxygenase activity" oxidation-reduction process endoplasmic reticulum membrane PF00743.21: FMO-like; PF13738.8: Pyr_redox_3; PF07992.16: Pyr_redox_2; PF13450.8: NAD_binding_8; PF13434.8: K_oxygenase; PF13454.8: NAD_binding_9; PF01946.19: Thi4; PF00070.29: Pyr_redox; PF00890.26: FAD_binding_2; PF12831.9: FAD_oxidored; PF03486.16: HI0933_like; PF01266.26: DAO; PF07991.14: IlvN; PF01262.23: AlaDh_PNT_C; PF11416.10: Syntaxin-5_N; PF14769.8: CLAMP; PF02737.20: 3HCDH_N; - HyS0057.24 HyS0057.024 727 - - 4 yes - 39.5457 38.25 36.054 54.62 44.3271 37.3046 39.0628 27.7601 42.117425 40.81585 33.41145 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: calcium/calmodulin-dependent protein kinase type IV-like [Hydra vulgaris] 1.60E-153 XP_002164168.2 calcium/calmodulin-dependent protein kinase type IV-like Danio rerio 456 97 1.17E-159 67.638 XP_002663771 Calcium/calmodulin-dependent protein kinase type IV CAMK4 protein serine/threonine kinase activity protein phosphorylation fibrillar center PF00069.27: Pkinase; PF07714.19: PK_Tyr_Ser-Thr; PF10707.11: YrbL-PhoP_reg; PF14531.8: Kinase-like; PF06293.16: Kdo; PF17667.3: Pkinase_fungal; - HyS0057.42 HyS0057.042 728 - - 4 yes - 8.10335 10.06 11.104 13.6138 22.1389 19.9703 14.2567 12.6561 10.7202875 21.0546 13.4564 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 hypothetical protein BRAFLDRAFT_124348 [Branchiostoma floridae] 1.80E-32 XP_002601588.1 ubiquilin-1 isoform 1 Homo sapiens 197 72 5.35E-56 46.341 NP_038466 LOW QUALITY PROTEIN: ubiquilin-2 UBQLN2 polyubiquitin modification-dependent protein binding negative regulation of G protein-coupled receptor internalization cytosol PF00240.25: ubiquitin; PF11976.10: Rad60-SLD; PF17830.3: STI1; PF18037.3: Ubiquitin_5; PF10302.11: DUF2407; PF18036.3: Ubiquitin_4; PF13881.8: Rad60-SLD_2; PF17925.3: TetR_C_20; - HyS0007.299 HyS0007.299 729 - - 4 yes - 12.595 21.1877 16.6093 10.0713 29.013 25.7314 21.9078 17.57 15.115825 27.3722 19.7389 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 WD repeat-containing protein 41-like isoform X1 [Pocillopora damicornis] 4.70E-87 XP_027038926.1 WD repeat-containing protein 41 Danio rerio 177 96 2.68E-49 28.289 NP_001025432 NA NA NA NA NA PF00400.34: WD40; PF16529.7: Ge1_WD40; PF11715.10: Nup160; PF08801.13: Nucleoporin_N; PF10030.11: DUF2272; PF12894.9: ANAPC4_WD40; - HyS0057.6 HyS0057.006 730 - - 4 yes - 15.6834 21.6645 20.237 10.7169 15.6763 14.9148 5.82007 9.09958 17.07545 15.29555 7.459825 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: uncharacterized protein LOC105843327, partial [Hydra vulgaris]" 5.60E-97 XP_012554013.1 no hits - - - - - - NA NA NA NA NA - - HyS0007.342 HyS0007.342 731 - - 4 yes - 214.879 140.044 109.55 149.135 8.0798 9.40733 0.528647 0.419152 153.402 8.743565 0.4738995 1 1 0 0 1 0 0 0 0 1 1 0 0 1 0 0 0 0 cnidarian tachylectin-related protein precursor [Hydractinia echinata] 1.50E-27 CAI77215.1 Fish-egg lectin-like precursor Danio rerio 80.5 89 1.47E-16 35.341 NP_001268934 Repellent NA phosphatidylinositol-3-phosphate binding ectoine biosynthetic process autophagosome membrane PF19193.2: Tectonin; PF06462.14: Hyd_WA; - HyS0070.34 HyS0070.034 732 - sex-linked-abnormal - - - 288.966 381.261 368.574 314.166 185.514 189.435 192.144 165.836 338.24175 187.4745 178.99 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100211907 [Hydra vulgaris] 1.60E-27 XP_002163558.2 no hits - - - - - - NA NA NA NA NA PF16492.7: Cadherin_C_2; - HyS0067.20 HyS0067.020 733 - sex-linked-abnormal 4 yes - 5.15821 4.89796 6.5189 13.3997 20.1509 17.8501 9.96486 10.7715 7.4936925 19.0005 10.36818 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: SET and MYND domain-containing protein 4-like [Hydra vulgaris] 3.60E-138 XP_012560518.1 "SET and MYND domain containing, class 4, member 3 " Drosophila melanogaster 234 61 1.35E-65 28.543 NP_725048 SET and MYND domain-containing protein 4 NA mannosyltransferase activity GPI anchor biosynthetic process endoplasmic reticulum membrane PF03901.19: Glyco_transf_22; PF00856.30: SET; PF01753.20: zf-MYND; PF13424.8: TPR_12; PF00515.30: TPR_1; PF07719.19: TPR_2; PF13181.8: TPR_8; PF03833.15: PolC_DP2; PF13174.8: TPR_6; - HyS0070.74 HyS0070.074 734 - sex-linked-abnormal - - - 10.9088 12.9926 12.8733 16.0045 29.6976 26.6129 20.4853 18.4209 13.1948 28.15525 19.4531 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: UPF0668 protein C10orf76 homolog [Hydra vulgaris] 5.50E-257 XP_012561198.1 armadillo-like helical domain-containing protein 3 Danio rerio 697 100 0 51.02 NP_956913 Armadillo-like helical domain-containing protein 3 ARMH3 NA NA integral component of membrane PF08427.12: DUF1741; PF11829.10: DUF3349; - HyS0113.31 HyS0113.031 735 - sex-linked-abnormal 4 yes - 3.94796 5.73213 7.01382 3.3802 11.9665 11.2304 2.47655 3.15788 5.0185275 11.59845 2.817215 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 proprotein convertase subtilisin/kexin type 6-like [Orbicella faveolata] 1.40E-195 XP_020628870.1 proprotein convertase subtilisin/kexin type 5 isoform X2 Mus musculus 787 91 0 32.094 XP_006526822 Proprotein convertase subtilisin/kexin type 6 PCSK6 serine-type endopeptidase activity proteolysis collagen-containing extracellular matrix PF00082.24: Peptidase_S8; PF14843.8: GF_recep_IV; PF15913.7: Furin-like_2; PF03302.15: VSP; PF16470.7: S8_pro-domain; PF01483.22: P_proprotein; PF00757.22: Furin-like; - HyS0057.87 HyS0057.087 736 - - 4 yes - 14.2441 10.5438 9.19871 8.18738 14.4249 23.3346 9.02002 10.7296 10.5434975 18.87975 9.87481 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: coiled-coil domain-containing protein 112-like [Hydra vulgaris] 6.90E-50 XP_002165637.3 coiled-coil domain-containing protein 112 isoform 1 precursor Homo sapiens 220 90 6.84E-64 34.576 NP_001035530 Coiled-coil domain-containing protein 112 NA NA NA NA PF06807.16: Clp1; PF11530.10: Pilin_PilX; - HyS0057.45 HyS0057.045 737 - - 4 yes - 32.0332 32.5623 34.6758 22.686 46.5417 39.1434 34.2753 33.2614 30.489325 42.84255 33.76835 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: tyrosine-protein kinase CSK-like [Hydra vulgaris] 2.50E-184 XP_012565373.1 tyrosine-protein kinase CSK isoform 1 Homo sapiens 487 96 1.72E-169 55.353 NP_001120662 Tyrosine-protein kinase CSK CSK non-membrane spanning protein tyrosine kinase activity peptidyl-tyrosine phosphorylation cell-cell junction PF07714.19: PK_Tyr_Ser-Thr; PF00069.27: Pkinase; PF00017.26: SH2; PF00018.30: SH3_1; PF07653.19: SH3_2; PF14604.8: SH3_9; PF17667.3: Pkinase_fungal; PF14531.8: Kinase-like; PF01636.25: APH; - HyS0067.30 HyS0067.030 738 - sex-linked-abnormal 4 yes - 13.0484 21.9681 18.3915 11.6846 31.7909 27.1227 21.8496 18.9019 16.27315 29.4568 20.37575 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: repulsive guidance molecule A-like [Hydra vulgaris] 4.60E-100 XP_002158844.1 RGM domain family member B isoform X3 Homo sapiens 161 55 5.30E-44 37.945 XP_011541648 Repulsive guidance molecule A RGMA coreceptor activity BMP signaling pathway anchored component of plasma membrane PF06534.15: RGM_C; PF06535.14: RGM_N; - HyS0007.365 HyS0007.365 739 - - 4 yes - 13.0008 16.1453 11.2894 13.1281 33.1287 28.2225 22.0891 20.6904 13.3909 30.6756 21.38975 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: ubiquitin-conjugating enzyme E2 Q1-like [Aplysia californica] 1.80E-84 XP_005103754.1 "uncharacterized protein Dmel_CG2924, isoform E " Drosophila melanogaster 328 99 2.05E-109 43.939 NP_001284819 Ubiquitin-conjugating enzyme NA ubiquitin conjugating enzyme activity protein ubiquitination neuronal cell body PF00179.28: UQ_con; PF05773.24: RWD; - HyS0113.35 HyS0113.035 740 - sex-linked-abnormal 4 yes - 10.0662 6.92626 7.48191 10.3169 42.7618 34.7114 27.0382 31.5261 8.6978175 38.7366 29.28215 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 OTU domain-containing protein 7B-like [Orbicella faveolata] 2.40E-92 XP_020631959.1 OTU domain-containing protein 7B Danio rerio 279 64 2.11E-81 37.444 NP_001071212 Proteasome endopeptidase complex NA zinc ion binding protein K11-linked deubiquitination nucleus PF02338.21: OTU; PF01754.18: zf-A20; PF14555.8: UBA_4; PF03943.15: TAP_C; PF00838.19: TCTP; PF05866.13: RusA; - HyS0057.4 HyS0057.004 741 - - 4 yes - 6.29116 8.22719 9.30104 6.14054 16.3196 14.0588 4.45994 6.52989 7.4899825 15.1892 5.494915 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: uncharacterized protein LOC105843327, partial [Hydra vulgaris]" 1.60E-96 XP_012554013.1 no hits - - - - - - NA NA NA NA NA PF18181.3: SLATT_1; - HyS0007.355 HyS0007.355 742 - - 4 yes - 55.8481 64.5607 64.7509 55.4722 62.1163 60.4033 52.0111 50.3895 60.157975 61.2598 51.2003 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: neural cell adhesion molecule 1-like [Hydra vulgaris] 5.20E-27 XP_002161571.3 basigin isoform 2 precursor Danio rerio 66.2 44 7.29E-11 31.443 NP_001299811 Basigin NA NA NA integral component of membrane PF13927.8: Ig_3; PF07679.18: I-set; PF00047.27: ig; PF13895.8: Ig_2; PF07686.19: V-set; PF08205.14: C2-set_2; - HyS0070.51 HyS0070.051 743 - sex-linked-abnormal - - - 30.2595 15.2408 19.9187 35.989 53.2705 51.4263 50.15 34.1939 25.352 52.3484 42.17195 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: peptidyl-prolyl cis-trans isomerase-like 2 [Hydra vulgaris] 6.90E-215 XP_012558477.1 RING-type E3 ubiquitin-protein ligase PPIL2 Danio rerio 615 100 0 60.113 NP_957285 Peptidyl-prolyl cis-trans isomerase PPIL2 ubiquitin-protein transferase activity protein ubiquitination nucleus PF00160.23: Pro_isomerase; PF04641.14: Rtf2; PF11789.10: zf-Nse; PF15906.7: zf-NOSIP; PF16675.7: FOXO_KIX_bdg; - HyS0620.2 HyS0620.002 744 - sex-linked-abnormal 4 yes - 7.33416 9.17777 4.75618 7.47391 25.7797 25.4858 14.9605 14.8677 7.185505 25.63275 14.9141 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: peroxisomal membrane protein 11B-like [Hydra vulgaris] 2.90E-06 XP_012564933.1 peroxisomal membrane protein 11A Danio rerio 40.4 77 4.84E-04 29.231 NP_001096590 NA NA NA NA NA PF05648.16: PEX11; - HyS0057.11 HyS0057.011 745 - - 4 yes - 14.1768 9.25909 10.4634 14.4009 19.732 19.1995 8.28226 8.74729 12.0750475 19.46575 8.514775 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: DNA-directed RNA polymerase III subunit RPC3-like [Hydra vulgaris] 3.60E-167 XP_012553722.1 DNA-directed RNA polymerase III subunit RPC3 isoform 2 Homo sapiens 422 39 8.05E-133 42.026 NP_001290385 Dna-directed rna polymerase iii POLR3C single-stranded DNA binding positive regulation of interferon-beta production RNA polymerase III complex PF08221.13: HTH_9; PF05645.15: RNA_pol_Rpc82; PF00610.23: DEP; PF02002.19: TFIIE_alpha; PF03547.20: Mem_trans; PF01978.21: TrmB; - HyS0067.18 HyS0067.018 746 - sex-linked-abnormal 4 yes - 15.2123 10.4863 10.5522 14.992 46.7684 37.6087 33.3524 29.0559 12.8107 42.18855 31.20415 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 LOW QUALITY PROTEIN: laminin-like protein epi-1 [Stylophora pistillata] 3.50E-263 XP_022783731.1 vacuolar protein sorting-associated protein 33B isoform 1 Homo sapiens 467 15 1.26E-143 41.472 NP_061138 MORN repeat-containing protein 1 MORN1 signaling receptor binding vesicle docking involved in exocytosis basement membrane PF00995.25: Sec1; PF00053.26: Laminin_EGF; PF02210.26: Laminin_G_2; PF00054.25: Laminin_G_1; PF02493.22: MORN; PF00052.20: Laminin_B; - HyS0070.27 HyS0070.027 747 - sex-linked-abnormal - - - 4.60785 5.51975 10.2024 9.234 13.7149 13.4452 2.72653 2.09255 7.391 13.58005 2.40954 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 PREDICTED: radixin-like [Hydra vulgaris] 2.60E-135 XP_002160112.1 radixin isoform a Mus musculus 573 100 0 51.959 NP_001098086 Ezrin Cytovillin NA actin binding regulation of plasma membrane bounded cell projection assembly cytoskeleton PF00769.21: ERM; PF00373.20: FERM_M; PF09380.12: FERM_C; PF09379.12: FERM_N; PF18477.3: PIN_9; - HyS0070.52 HyS0070.052 748 - sex-linked-abnormal - - - 54.4312 45.1426 28.7073 40.6235 51.1989 40.8929 34.3083 35.0593 42.22615 46.0459 34.6838 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: proline-rich protein 5-like [Hydra vulgaris] 4.20E-47 XP_012561810.1 proline-rich protein 5 isoform 2 Mus musculus 135 65 1.18E-35 34.518 NP_001333591 NA NA NA NA NA PF08539.13: HbrB; PF12123.10: CBD_PlyG; - HyS0067.37 HyS0067.037 749 - sex-linked-abnormal 4 yes - 28.1878 32.6846 29.9508 18.0585 21.2443 24.0351 10.3448 11.7606 27.220425 22.6397 11.0527 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: atrial natriuretic peptide receptor 1-like isoform X1 [Hydra vulgaris] 0 XP_004209910.2 "uncharacterized protein Dmel_CG10738, isoform F " Drosophila melanogaster 640 94 0 36.114 NP_001246743 Atrial natriuretic peptide receptor 1 NA guanylate cyclase activity cGMP biosynthetic process integral component of membrane PF00211.22: Guanylate_cyc; PF01094.30: ANF_receptor; PF07714.19: PK_Tyr_Ser-Thr; PF00069.27: Pkinase; PF07701.16: HNOBA; PF09889.11: DUF2116; - HyS0067.21 HyS0067.021 750 - sex-linked-abnormal 4 yes - 17.5652 20.372 19.6286 19.2005 37.6145 32.0053 19.1545 22.7893 19.191575 34.8099 20.9719 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: transducin-like enhancer protein 4 [Hydra vulgaris] 0 XP_012560187.1 transducin-like enhancer protein 1 isoform X17 Homo sapiens 844 43 0 59.777 XP_006717326 Enhancer of split groucho NA CRD domain binding "regulation of transcription, DNA-templated" nucleus PF03920.17: TLE_N; PF10373.11: EST1_DNA_bind; PF10374.11: EST1; PF00400.34: WD40; PF13638.8: PIN_4; PF12894.9: ANAPC4_WD40; PF02239.18: Cytochrom_D1; PF01166.20: TSC22; PF17005.7: WD40_like; - HyS0057.53 HyS0057.053 751 - - 4 yes - 23.6565 18.2199 18.7316 21.7967 41.458 35.4166 29.1395 17.2696 20.601175 38.4373 23.20455 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF07166.13: DUF1398; - HyS0007.375 HyS0007.375 752 - - 4 yes - 6.9519 7.27151 5.92279 6.44887 27.6894 23.6603 8.34546 12.0829 6.6487675 25.67485 10.21418 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: zinc transporter ZIP1-like [Hydra vulgaris] 6.80E-68 XP_002161715.1 zinc transporter ZIP1 Danio rerio 100 56 8.24E-23 40.517 NP_997748 Zinc transporter ZIP1 NA metal ion transmembrane transporter activity metal ion transport integral component of membrane PF02535.24: Zip; - HyS0070.35 HyS0070.035 753 - sex-linked-abnormal - - - 13.8654 10.4569 11.0098 14.2014 36.3801 37.517 21.444 21.3361 12.383375 36.94855 21.39005 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: WD repeat-containing protein 70-like [Hydra vulgaris] 1.30E-175 XP_002168709.1 WD repeat-containing protein 70 Danio rerio 585 95 0 48.35 XP_021334902 WD repeat-containing protein 70 WDR70 enzyme binding regulation of DNA double-strand break processing site of double-strand break PF00400.34: WD40; PF12894.9: ANAPC4_WD40; PF08648.14: SNRNP27; PF02239.18: Cytochrom_D1; PF05432.13: BSP_II; - HyS0067.36 HyS0067.036 754 - sex-linked-abnormal 4 yes - 37.9533 43.4943 51.5071 28.3656 32.1157 28.9487 13.3384 15.743 40.330075 30.5322 14.5407 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: LOW QUALITY PROTEIN: ras GTPase-activating-like protein IQGAP1 [Hydra vulgaris] 0 XP_012567030.1 ras GTPase-activating-like protein IQGAP1 Homo sapiens 1665 99 0 52.027 NP_003861 Iq motif containing gtpase activating NA "phosphatidylinositol-3,4,5-trisphosphate binding" regulation of GTPase activity cell leading edge PF00616.21: RasGAP; PF03836.17: RasGAP_C; PF00612.29: IQ; PF00307.33: CH; PF00397.28: WW; PF05099.15: TerB; - HyS0007.411 HyS0007.411 755 - - 4 yes - 6.00258 29.7496 27.4742 7.69491 55.3927 41.2463 39.1602 23.9471 17.7303225 48.3195 31.55365 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: chondroitin sulfate synthase 1-like [Hydra vulgaris] 2.80E-28 XP_012562605.1 chondroitin sulfate synthase 1 precursor Danio rerio 94.7 92 4.76E-23 52.5 NP_997843 Hexosyltransferase NA acetylgalactosaminyltransferase activity glycoprotein biosynthetic process Golgi cisterna membrane PF05679.18: CHGN; PF02709.16: Glyco_transf_7C; PF10111.11: Glyco_tranf_2_2; - HyS0007.347 HyS0007.347 756 - - 4 yes - 14.4379 32.9859 24.0547 12.468 22.6175 19.0117 1.95724 4.19689 20.986625 20.8146 3.077065 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 PREDICTED: RNA-binding protein MEX3B-like [Hydra vulgaris] 8.70E-187 XP_012561659.1 RNA-binding E3 ubiquitin-protein ligase MEX3C Mus musculus 329 80 1.80E-103 47.034 NP_001034303 RING-type domain-containing protein (Fragment) MEX3B RNA binding protein autophosphorylation nucleoplasm PF00013.31: KH_1; PF13920.8: zf-C3HC4_3; PF14447.8: Prok-RING_4; PF13639.8: zf-RING_2; PF07650.19: KH_2; PF13083.8: KH_4; PF14634.8: zf-RING_5; PF13923.8: zf-C3HC4_2; PF14570.8: zf-RING_4; - HyS0007.267 HyS0007.267 757 - - 4 yes - 9.76661 6.39289 5.10553 3.21985 29.9036 25.4888 9.74119 9.33141 6.12122 27.6962 9.5363 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: protein RRNAD1-like isoform X1 [Hydra vulgaris] 5.80E-154 XP_012556070.1 protein RRNAD1 isoform X1 Danio rerio 240 95 2.21E-70 29.289 XP_009290620 NA NA NA NA NA PF13679.8: Methyltransf_32; PF08123.15: DOT1; PF00398.22: RrnaAD; PF05175.16: MTS; PF02353.22: CMAS; PF13489.8: Methyltransf_23; PF13649.8: Methyltransf_25; - HyS0067.75 HyS0067.075 758 - sex-linked-abnormal 4 yes - 8.02196 8.41446 7.71974 4.95358 20.4912 18.4686 1.75099 0.694283 7.277435 19.4799 1.2226365 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0057.86 HyS0057.086 759 - - 4 yes - 14.6963 9.93859 4.17927 16.8068 40.718 34.2077 22.0074 15.3323 11.40524 37.46285 18.66985 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100201999 [Hydra vulgaris] 1.50E-39 XP_002164179.2 ubiquitin-like protein 7a Danio rerio 72.8 91 4.75E-13 26.176 NP_001017765 NA NA NA NA NA PF00240.25: ubiquitin; PF14555.8: UBA_4; PF18396.3: TBK1_ULD; PF14560.8: Ubiquitin_2; PF02845.18: CUE; PF11620.10: GABP-alpha; PF18037.3: Ubiquitin_5; PF04699.16: P16-Arc; - HyS0007.335 HyS0007.335 760 - - 4 yes - 4.63183 8.13186 5.62127 5.45751 30.1632 26.8769 10.619 8.61215 5.9606175 28.52005 9.615575 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: probable UDP-sugar transporter protein SLC35A4 [Hydra vulgaris] 5.10E-66 XP_012555641.1 probable UDP-sugar transporter protein SLC35A4 Danio rerio 193 50 2.62E-56 43.307 NP_001242972 Heterogeneous nuclear ribonucleoprotein A3 SLC35A4 pyrimidine nucleotide-sugar transmembrane transporter activity pyrimidine nucleotide-sugar transmembrane transport Golgi membrane PF04142.17: Nuc_sug_transp; PF00646.35: F-box; PF07155.14: ECF-ribofla_trS; PF12937.9: F-box-like; PF06881.13: Elongin_A; PF15966.7: F-box_4; - HyS0070.28 HyS0070.028 761 - sex-linked-abnormal - - - 40.3148 52.1856 43.9339 29.9106 54.519 55.6508 30.617 41.3438 41.586225 55.0849 35.9804 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: radixin-like [Hydra vulgaris] 4.20E-175 XP_002160112.1 radixin isoform a Mus musculus 715 47 0 64.068 NP_001098086 Ezrin Cytovillin NA actin binding morphogenesis of an epithelium cytoskeleton PF00769.21: ERM; PF09380.12: FERM_C; PF00400.34: WD40; PF00373.20: FERM_M; PF09379.12: FERM_N; PF13445.8: zf-RING_UBOX; PF13923.8: zf-C3HC4_2; PF11789.10: zf-Nse; PF00097.27: zf-C3HC4; PF14634.8: zf-RING_5; PF15227.8: zf-C3HC4_4; PF13639.8: zf-RING_2; PF13920.8: zf-C3HC4_3; PF04564.17: U-box; PF16685.7: zf-RING_10; PF02176.20: zf-TRAF; PF02239.18: Cytochrom_D1; PF15965.7: zf-TRAF_2; PF03145.18: Sina; PF14835.8: zf-RING_6; PF12861.9: zf-ANAPC11; PF17121.7: zf-C3HC4_5; - HyS0007.358 HyS0007.358 762 - - 4 yes - 0 0 10.5137 14.2653 32.0022 23.341 4.4718 10.6198 6.19475 27.6716 7.5458 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: glutaredoxin-like protein C5orf63 homolog [Hydra vulgaris] 1.30E-19 XP_012567031.1 glutaredoxin-like protein C5orf63 homolog Mus musculus 79.3 99 9.88E-20 44.304 NP_084185 Glutaredoxin NA "transferase activity, transferring acyl groups other than amino-acyl groups" oxidation-reduction process ribosome PF05768.16: Glrx-like; PF00462.26: Glutaredoxin; - HyS0070.71 HyS0070.071 763 - sex-linked-abnormal - - - 4.59265 5.40498 5.36487 5.53959 30.8288 26.2532 8.81516 7.97237 5.2255225 28.541 8.393765 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC101240704 [Hydra vulgaris] 6.60E-25 XP_004207065.2 uncharacterized protein Dmel_CG5466 Drosophila melanogaster 50.4 16 4.80E-05 28.889 NP_650901 NA NA NA NA NA PF09806.11: CDK2AP; - HyS0067.76 HyS0067.076 764 - sex-linked-abnormal 4 yes - 16.6345 10.9612 22.0543 11.0496 23.3173 25.0462 3.536 4.5302 15.1749 24.18175 4.0331 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 PREDICTED: cartilage oligomeric matrix protein-like [Hydra vulgaris] 1.30E-172 XP_012558303.1 thrombospondin-3 isoform 3 precursor Homo sapiens 524 63 2.48E-173 52.964 NP_001239537 Thrombospondin Bii NA heparin binding cell adhesion extracellular region PF05735.14: TSP_C; PF02412.20: TSP_3; PF00008.29: EGF; PF13385.8: Laminin_G_3; PF12947.9: EGF_3; PF13878.8: zf-C2H2_3; PF12662.9: cEGF; PF06247.13: Plasmod_Pvs28; PF11598.10: COMP; - HyS0007.396 HyS0007.396 765 - - 4 yes - 27.9045 37.8043 28.1133 28.2023 48.089 40.4365 24.5537 23.4078 30.5061 44.26275 23.98075 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: synaptotagmin-7-like [Hydra vulgaris] 1.70E-92 XP_002161536.1 synaptotagmin-7 isoform 3 Homo sapiens 134 93 1.47E-33 26.211 NP_001287702 Synaptotagmin IV [Tribolium castaneum] (Fragment) NA NA NA membrane PF00168.32: C2; PF04276.14: DUF443; PF03739.16: LptF_LptG; PF11346.10: DUF3149; - HyS0057.25 HyS0057.025 766 - - 4 yes - 28.6435 14.5074 15.8264 34.6182 65.6097 60.0938 41.8325 42.9649 23.398875 62.85175 42.3987 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein C1orf43 homolog [Hydra vulgaris] 1.10E-72 XP_002160221.3 protein C1orf43 isoform 6 Homo sapiens 69.3 67 8.93E-13 29.545 NP_001284649 NA NA NA NA NA PF07406.13: NICE-3; PF13559.8: DUF4129; - HyS0007.336 HyS0007.336 767 - - 4 yes - 10.4416 11.7032 6.58574 10.208 70.774 71.2325 57.5226 43.3786 9.734635 71.00325 50.4506 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: TIMELESS-interacting protein-like [Hydra vulgaris] 9.10E-30 XP_004206439.1 TIMELESS-interacting protein isoform 1 Homo sapiens 80.5 78 2.38E-16 26.887 NP_060328 TIMELESS-interacting protein (Fragment) NA NA replication fork protection nucleus PF07962.14: Swi3; - HyS0070.16 HyS0070.016 768 - sex-linked-abnormal - - - 14.9717 21.717 19.9204 14.5905 37.2275 36.7123 17.0629 15.5463 17.7999 36.9699 16.3046 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: mannosyl-oligosaccharide 1,2-alpha-mannosidase IA-like [Hydra vulgaris]" 2.30E-222 XP_002165962.2 "mannosyl-oligosaccharide 1,2-alpha-mannosidase IB isoform X1 " Homo sapiens 665 99 0 54.516 XP_006710365 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA" MAN1A1 "mannosyl-oligosaccharide 1,2-alpha-mannosidase activity" glycoprotein metabolic process endoplasmic reticulum-Golgi intermediate compartment PF01532.22: Glyco_hydro_47; PF11169.10: DUF2956; PF09216.12: Pfg27; PF09787.11: Golgin_A5; - HyS0067.48 HyS0067.048 769 - sex-linked-abnormal 4 yes - 11.0819 10.5899 8.6062 8.84693 58.8617 47.1661 29.5845 31.1743 9.7812325 53.0139 30.3794 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: regulation of nuclear pre-mRNA domain-containing protein 2-like [Hydra vulgaris] 2.50E-67 XP_012564871.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 6 Homo sapiens 172 27 2.91E-43 31.944 NP_001374045 Regulation of nuclear pre-mRNA domain-containing protein 2 RPRD2 RNA polymerase II complex binding mRNA 3'-end processing "RNA polymerase II, holoenzyme" PF04818.15: CID; PF16566.7: CREPT; - HyS0007.369 HyS0007.369 770 - - 4 yes - 25.9981 18.0871 15.7885 23.7151 54.0754 51.0369 33.0808 24.8728 20.8972 52.55615 28.9768 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: ubiquitin-conjugating enzyme E2 R2-like [Hydra vulgaris] 2.80E-86 XP_012555857.1 ubiquitin-conjugating enzyme E2 R1 isoform 1 Mus musculus 305 95 1.11E-104 62.009 NP_808281 Ubiquitin-conjugating enzyme NA ATP binding protein K48-linked ubiquitination nuclear speck PF00179.28: UQ_con; PF05773.24: RWD; - HyS0007.341 HyS0007.341 771 - - 4 yes - 7.19126 16.7793 11.4903 6.85628 32.4913 27.0661 4.05259 6.47778 10.579285 29.7787 5.265185 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1-like [Hydra vulgaris] 5.70E-273 XP_012566940.1 "beta-1,4-N-acetylgalactosaminyltransferase 3 " Danio rerio 355 96 4.24E-111 31.768 XP_021327218 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 B4GALNT4 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity NA Golgi cisterna membrane PF05679.18: CHGN; PF02709.16: Glyco_transf_7C; PF07691.14: PA14; PF10528.11: GLEYA; - HyS0067.25 HyS0067.025 772 - sex-linked-abnormal 4 yes - 8.42492 4.87828 8.23539 7.19045 32.3978 24.8482 3.11681 4.14615 7.18226 28.623 3.63148 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 PREDICTED: uncharacterized protein LOC100208656 isoform X2 [Hydra vulgaris] 4.40E-11 XP_012556596.1 GRB2-associated-binding protein 3 Danio rerio 59.3 45 7.26E-08 30.769 XP_001337715 NA NA NA NA NA PF00169.31: PH; PF12814.9: Mcp5_PH; PF08458.12: PH_2; PF15413.8: PH_11; - HyS0057.109 HyS0057.109 773 - - 4 yes - 65.9542 49.6659 53.9643 59.1704 62.8892 52.7319 30.4855 33.7082 57.1887 57.81055 32.09685 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC101238046 [Hydra vulgaris] 6.40E-28 XP_004206856.1 zinc finger protein 608 isoform X5 Homo sapiens 81.6 16 5.02E-14 26.423 XP_011541824 Zinc finger protein 609 (Fragment) NA nucleic acid binding NA NA PF13894.8: zf-C2H2_4; PF00096.28: zf-C2H2; - HyS0113.28 HyS0113.028 774 - sex-linked-abnormal 4 yes - 10.1795 6.59714 7.98362 7.84753 38.0452 31.7458 8.11889 9.25479 8.1519475 34.8955 8.68684 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC101239053 [Hydra vulgaris] 3.20E-68 XP_004212422.2 uncharacterized protein LOC566646 isoform X1 Danio rerio 60.8 23 1.56E-08 34.188 XP_695016 NA NA NA NA NA PF09451.12: ATG27; PF05485.14: THAP; PF02157.17: Man-6-P_recep; PF14775.8: NYD-SP28_assoc; - HyS0067.34 HyS0067.034 775 - sex-linked-abnormal 4 yes - 7.88478 12.2542 11.5445 5.05939 42.3419 31.3622 8.6426 9.38374 9.1857175 36.85205 9.01317 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 Hdac3 [Hydractinia echinata] 3.10E-261 APW77292.1 histone deacetylase 3 Danio rerio 629 97 0 69.34 NP_957284 Histone deacetylase HDAC3 histone deacetylase activity histone H3 deacetylation nucleus PF00850.21: Hist_deacetyl; - HyS0057.29 HyS0057.029 776 - - 4 yes - 7.82219 7.59213 12.7042 7.28252 35.48 29.4374 3.66623 4.36115 8.85026 32.4587 4.01369 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 PREDICTED: growth factor receptor-bound protein 14-like [Hydra vulgaris] 1.00E-142 XP_004207418.2 growth factor receptor-bound protein 10 isoform X11 Homo sapiens 154 74 2.53E-39 26.914 XP_011513625 Growth factor receptor bound protein (Fragment) NA NA NA NA PF00017.26: SH2; PF00169.31: PH; PF08947.12: BPS; - HyS0007.300 HyS0007.300 777 - - 4 yes - 15.2314 18.5399 6.86771 5.19134 48.9243 41.4343 14.4654 14.0675 11.4575875 45.1793 14.26645 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC105843359 [Hydra vulgaris] 5.40E-38 XP_012554080.1 no hits - - - - - - NA NA NA NA NA PF08271.14: TF_Zn_Ribbon; - HyS0007.340 HyS0007.340 778 - - 4 yes - 9.175 16.4727 7.37483 14.8692 40.5627 40.1328 8.10892 10.2863 11.9729325 40.34775 9.19761 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: mono [ADP-ribose] polymerase PARP16-like [Hydra vulgaris] 4.00E-91 XP_002164087.1 protein mono-ADP-ribosyltransferase PARP16 Danio rerio 229 96 3.50E-72 38.272 NP_998071 Poly [ADP-ribose] polymerase PARP16 NAD+ ADP-ribosyltransferase activity protein mono-ADP-ribosylation endoplasmic reticulum tubular network PF18084.3: ARTD15_N; PF00644.22: PARP; - HyS0067.38 HyS0067.038 779 - sex-linked-abnormal 4 yes - 697.768 614.688 533.505 487.473 94.3496 159.83 79.0441 110.682 583.3585 127.0898 94.86305 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein ZK643.6-like [Hydra vulgaris] 1.50E-38 XP_002167799.2 ShKT domain-containing protein Caenorhabditis elegans 45.1 24 1.76E-04 30.952 NP_001254149 NA NA NA NA NA PF01549.26: ShK; - HyS0113.26 HyS0113.026 780 - sex-linked-abnormal 4 yes - 17.2076 15.772 16.6793 26.7729 61.2608 51.911 24.636 20.4784 19.10795 56.5859 22.5572 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase-like [Hydra vulgaris]" 5.30E-95 XP_002160180.1 "trans-1,2-dihydrobenzene-1,2-diol dehydrogenase " Mus musculus 241 50 1.37E-72 40.122 NP_082179 Dimeric dihydrodiol dehydrogenase DHDH oxidoreductase activity oxidation-reduction process integral component of peroxisomal membrane PF04757.16: Pex2_Pex12; PF01408.24: GFO_IDH_MocA; PF03807.19: F420_oxidored; - HyS0007.325 HyS0007.325 781 - - 4 yes - 18.2495 9.97141 14.3817 19.0666 56.1505 51.1952 21.4447 16.5831 15.4173025 53.67285 19.0139 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: phenylalanine--tRNA ligase, mitochondrial-like [Hydra vulgaris]" 4.60E-172 XP_004206650.2 "phenylalanine--tRNA ligase, mitochondrial isoform 1 " Homo sapiens 451 91 1.22E-155 51.493 NP_001305801 Phenylalanyl-tRNA synthetase FARS2 phenylalanine-tRNA ligase activity phenylalanyl-tRNA aminoacylation cytoplasm PF01409.22: tRNA-synt_2d; PF03147.16: FDX-ACB; - HyS0070.19 HyS0070.019 782 - sex-linked-abnormal - - - 32.359 34.9771 33.9783 53.7256 44.4493 36.3211 3.09477 6.19922 38.76 40.3852 4.646995 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA - - HyS0067.27 HyS0067.027 783 - sex-linked-abnormal 4 yes - 7.77294 6.01495 10.6104 10.9641 51.5182 49.6436 14.9726 13.6401 8.8405975 50.5809 14.30635 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: 39S ribosomal protein L37, mitochondrial-like [Hydra vulgaris]" 3.40E-97 XP_004210084.1 "39S ribosomal protein L37, mitochondrial precursor " Mus musculus 55.8 63 3.12E-07 25.475 NP_079776 NA NA NA NA NA PF07147.14: PDCD9; PF08771.13: FRB_dom; - HyS0070.50 HyS0070.050 784 - sex-linked-abnormal - - - 14.514 9.39632 11.7199 8.65852 47.1712 42.9911 8.23267 8.98517 11.072185 45.08115 8.60892 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: nucleolar complex protein 3 homolog [Hydra vulgaris] 1.70E-132 XP_012557655.1 nucleolar complex protein 3 homolog Danio rerio 462 93 2.16E-150 40.268 NP_001002863 Nucleolar complex protein 3 homolog NOC3L chromatin binding fat cell differentiation nucleolus PF07540.13: NOC3p; PF03914.19: CBF; PF07840.14: FadR_C; - HyS0070.53 HyS0070.053 785 - sex-linked-abnormal - - - 19.4623 9.36636 10.7866 11.6942 55.6162 67.1566 26.4556 22.6791 12.827365 61.3864 24.56735 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: cell growth-regulating nucleolar protein-like [Hydra vulgaris] 8.90E-77 XP_012561808.1 cell growth-regulating nucleolar protein Danio rerio 205 100 3.24E-63 38.298 NP_956973 cell growth-regulating nucleolar protein isoform X1 LYAR DNA binding negative regulation of transcription by RNA polymerase II nucleolus PF08790.13: zf-LYAR; PF16276.7: NPM1-C; PF02176.20: zf-TRAF; PF17848.3: zf-ACC; PF02724.16: CDC45; PF17959.3: EF-hand_14; PF01485.23: IBR; - HyS0007.357 HyS0007.357 786 - - 4 yes - 6.58614 5.47166 5.39621 8.14965 55.8565 47.6697 13.4029 14.1692 6.400915 51.7631 13.78605 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: G patch domain and ankyrin repeat-containing protein 1 homolog [Hydra vulgaris] 1.70E-55 XP_012567032.1 uncharacterized protein Dmel_CG8152 Drosophila melanogaster 168 94 5.58E-48 31.361 NP_611028 G patch domain and ankyrin repeats-containing protein 1 (Fragment) NA nucleic acid binding NA NA PF01585.25: G-patch; PF13637.8: Ank_4; PF12796.9: Ank_2; PF13857.8: Ank_5; PF13606.8: Ank_3; PF00023.32: Ank; PF08010.13: Phage_30_3; PF12656.9: G-patch_2; - HyS0070.18 HyS0070.018 787 - sex-linked-abnormal - - - 26.1604 27.8184 23.1815 13.812 51.9504 43.6375 6.63839 8.43699 22.743075 47.79395 7.53769 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 solute carrier family 28 member 3-like isoform X2 [Exaiptasia pallida] 2.60E-149 XP_020912178.1 sodium/nucleoside cotransporter 1 isoform X1 Danio rerio 524 85 1.07E-178 51.149 XP_005159357 Sodium/nucleoside cotransporter SLC28A3 nucleoside transmembrane transporter activity nucleoside transmembrane transport integral component of plasma membrane PF07662.15: Nucleos_tra2_C; PF01773.22: Nucleos_tra2_N; PF07670.16: Gate; - HyS0070.33 HyS0070.033 788 - sex-linked-abnormal - - - 11.5625 6.50906 5.89502 8.4843 55.3772 53.866 16.918 11.2119 8.11272 54.6216 14.06495 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: adrenodoxin-like isoform X2 [Hydra vulgaris] 5.20E-43 XP_012555233.1 ferredoxin 2 Drosophila melanogaster 124 65 2.17E-35 53.543 NP_647889 Cytochrome c oxidase assembly protein subunit 15 NA "2 iron, 2 sulfur cluster binding" electron transport chain mitochondrial matrix PF00111.29: Fer2; - HyS0113.38 HyS0113.038 789 - sex-linked-abnormal 4 yes - 8.3663 6.59496 8.6996 3.1496 61.9431 55.1992 18.7248 13.7827 6.702615 58.57115 16.25375 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: vesicle transport protein USE1-like [Hydra vulgaris] 2.80E-68 XP_002164600.1 vesicle transport protein USE1 Danio rerio 183 97 4.13E-56 38.697 NP_956618 Unconventional SNARE in the ER 1 homolog USE1 NA NA integral component of membrane PF09753.11: Use1; PF06024.14: Orf78; PF20077.1: CcmD_alt; PF08656.12: DASH_Dad3; - HyS0007.370 HyS0007.370 790 - - 4 yes - 8.9007 14.6472 8.7166 15.9013 79.3635 70.8479 34.9822 26.2958 12.04145 75.1057 30.639 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: von Willebrand factor A domain-containing protein 9-like [Hydra vulgaris] 5.50E-185 XP_012559119.1 von Willebrand factor A domain-containing protein 9 isoform X1 Danio rerio 386 96 2.29E-128 41.929 XP_005159109 LOW QUALITY PROTEIN: von Willebrand factor A domain-containing protein 9 INTS14 NA snRNA 3'-end processing integrator complex PF19435.1: IntS14; PF13519.8: VWA_2; PF00092.30: VWA; - HyS0057.105 HyS0057.105 791 - - 4 yes - 62.0103 38.8874 46.6669 82.6337 110.669 97.877 70.0679 48.5676 57.549575 104.273 59.31775 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: solute carrier family 25 member 46-like [Hydra vulgaris] 7.40E-118 XP_012556083.1 solute carrier family 25 member 46 isoform 3 Homo sapiens 257 85 3.11E-82 41.358 NP_001290179 Solute carrier family SLC25A46 protein binding mitochondrial membrane fission mitochondrial outer membrane PF00153.29: Mito_carr; PF18078.3: Thioredoxin_11; - HyS0070.10 HyS0070.010 792 - sex-linked-abnormal - - - 14.5055 12.6097 18.8357 13.512 65.8891 52.5551 11.368 11.5427 14.865725 59.2221 11.45535 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: ubiquitin-conjugating enzyme E2 J1-like [Hydra vulgaris] 1.40E-84 XP_012556180.1 ubiquitin-conjugating enzyme E2 J1 isoform X2 Homo sapiens 285 51 9.61E-95 70.811 XP_011534190 Gamma-aminobutyric acid receptor subunit rho-3 UBE2J1 ubiquitin conjugating enzyme activity "negative regulation of retrograde protein transport, ER to cytosol" integral component of membrane PF00179.28: UQ_con; PF05773.24: RWD; PF03153.15: TFIIA; - HyS0070.75 HyS0070.075 793 - sex-linked-abnormal - - - 5.51517 6.16178 9.54568 6.76037 56.2287 46.6126 1.58219 1.00363 6.99575 51.42065 1.29291 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 no hits - - sphingosine 1-phosphate receptor 3 Mus musculus 50.8 79 1.04E-05 25.253 NP_034231 NA NA NA NA NA PF00001.23: 7tm_1; - HyS0067.35 HyS0067.035 794 - sex-linked-abnormal 4 yes - 10.2643 7.35389 3.22733 6.92354 60.9083 53.8775 7.77565 6.74881 6.942265 57.3929 7.26223 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 uncharacterized protein LOC113672688 [Pocillopora damicornis] 4.40E-18 XP_027044817.1 no hits - - - - - - NA NA NA NA NA PF06127.13: DUF962; PF09843.11: DUF2070; - HyS0070.30 HyS0070.030 795 - sex-linked-abnormal - - - 15.5756 31.1174 25.8379 19.4642 83.3632 69.3797 23.1559 26.793 22.998775 76.37145 24.97445 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: sestrin-1-like [Hydra vulgaris] 1.70E-158 XP_002165651.2 sestrin-1 isoform X2 Danio rerio 389 87 3.69E-128 40.909 XP_005160728 Sestrin-1 SESN1 leucine binding regulation of response to reactive oxygen species nucleus PF04636.15: PA26; - HyS0007.359 HyS0007.359 796 - - 4 yes - 17.9842 20.5078 17.2835 24.4573 88.9912 71.0198 30.9844 23.8076 20.0582 80.0055 27.396 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: bidirectional sugar transporter SWEET15-like [Hydra vulgaris] 1.50E-57 XP_004206288.1 sugar transporter SWEET1 isoform a Homo sapiens 117 92 1.99E-31 34.45 NP_061333 Sugar transporter SWEET NA NA carbohydrate transport plasma membrane PF03083.18: MtN3_slv; PF16311.7: TMEM100; PF04193.16: PQ-loop; - HyS0057.2 HyS0057.002 797 - - 4 yes - 31.994 27.9868 31.4689 41.5732 87.2566 80.4151 29.9902 29.9949 33.255725 83.83585 29.99255 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: long-chain-fatty-acid--CoA ligase ACSBG2-like [Hydra vulgaris] 4.90E-275 XP_004208091.2 long-chain-fatty-acid--CoA ligase ACSBG2 isoform X1 Danio rerio 705 74 0 49.648 XP_005166846 Long-chain-fatty-acid--CoA ligase 6 ACSBG2 ligase activity NA NA PF00501.30: AMP-binding; PF10601.11: zf-LITAF-like; PF14569.8: zf-UDP; - HyS0057.104 HyS0057.104 798 - - 4 yes - 7.91071 15.1455 12.2747 9.98652 80.4547 68.1176 13.486 20.1308 11.3293575 74.28615 16.8084 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 uncharacterized protein LOC110059583 isoform X3 [Orbicella faveolata] 2.30E-23 XP_020621963.1 low-density lipoprotein receptor-related protein 4 isoform X1 Danio rerio 75.5 19 5.89E-13 40.86 XP_017212642 NA NA NA NA NA PF19028.2: TSP1_spondin; PF12662.9: cEGF; PF14670.8: FXa_inhibition; PF00090.21: TSP_1; PF07645.17: EGF_CA; - HyS0057.99 HyS0057.099 799 - - 4 yes - 420.915 439.151 448.317 408.705 192.904 279.776 170.113 187.606 429.272 236.34 178.8595 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - Uncharacterized protein CELE_Y105E8B.1 Caenorhabditis elegans 90.1 99 2.56E-20 31.579 NP_001300453 Tropomyosin-1 NA NA NA NA PF00261.22: Tropomyosin; PF12718.9: Tropomyosin_1; PF07926.14: TPR_MLP1_2; PF12795.9: MscS_porin; PF19220.2: Crescentin; PF07889.14: DUF1664; PF05622.14: HOOK; PF04871.15: Uso1_p115_C; PF08581.12: Tup_N; PF01576.21: Myosin_tail_1; PF06009.14: Laminin_II; PF00769.21: ERM; PF11559.10: ADIP; PF08614.13: ATG16; PF13870.8: DUF4201; PF08702.12: Fib_alpha; PF06005.14: ZapB; PF05377.13: FlaC_arch; PF19111.2: DUF5798; PF13851.8: GAS; PF16535.7: T3SSipB; PF09325.12: Vps5; PF06160.14: EzrA; PF04632.14: FUSC; PF06013.14: WXG100; PF15619.8: Lebercilin; PF06148.13: COG2; PF06818.17: Fez1; PF18595.3: DHR10; PF05557.15: MAD; PF02646.18: RmuC; PF05667.13: DUF812; PF13166.8: AAA_13; PF04108.14: ATG17_like; PF17675.3: APG6_N; PF10473.11: CENP-F_leu_zip; PF05531.14: NPV_P10; PF05266.16: DUF724; PF11932.10: DUF3450; PF07888.13: CALCOCO1; PF09728.11: Taxilin; PF10046.11: BLOC1_2; PF05335.15: DUF745; PF10498.11: IFT57; - HyS0057.8 HyS0057.008 800 - - 4 yes - 8.44021 6.50723 4.76778 2.44237 85.9627 79.7626 21.5602 23.9766 5.5393975 82.86265 22.7684 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: PCNA-associated factor-like [Hydra vulgaris] 2.50E-09 XP_002163831.1 PCNA-associated factor Mus musculus 46.6 45 6.22E-06 41.25 NP_080791 PCNA-associated factor PCLAF chromatin binding regulation of cell cycle nucleus PF15715.7: PAF; - HyS0070.29 HyS0070.029 801 - sex-linked-abnormal - - - 14.8729 11.0501 13.9148 16.7837 94.315 78.1331 27.4045 23.0797 14.155375 86.22405 25.2421 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 "PREDICTED: 39S ribosomal protein L18, mitochondrial-like [Hydra vulgaris]" 1.20E-68 XP_012564547.1 "39S ribosomal protein L18, mitochondrial isoform X1 " Mus musculus 93.2 58 3.94E-22 35 XP_006523407 NA NA NA NA NA PF00861.24: Ribosomal_L18p; - HyS0067.22 HyS0067.022 802 - sex-linked-abnormal 4 yes - 13.6989 17.3789 16.2905 15.8313 73.3691 79.9545 12.1959 16.2196 15.7999 76.6618 14.20775 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: NF-kappa-B-activating protein-like [Hydra vulgaris] 2.20E-61 XP_004206648.1 NF-kappa-B-activating protein Danio rerio 177 45 5.09E-52 66.917 NP_001003414 SynMuv product domain containing protein NKAP chromatin binding Notch signaling pathway ESC/E(Z) complex PF06047.13: Nkap_C; PF15692.7: NKAP; PF14631.8: FancD2; PF04499.17: SAPS; - HyS0057.130 HyS0057.130 803 - - 4 yes - 81.3437 97.4593 75.8418 102.789 159.486 164.744 93.27 104.706 89.35845 162.115 98.988 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 nuclear lamin protein [Hydra vulgaris] 2.20E-142 AWU22326.1 lamin isoform C Homo sapiens 322 92 4.39E-102 38.374 NP_001269554 Nuclear lamin LAMIN NA NA intermediate filament PF00038.23: Filament; PF00932.21: LTD; PF05791.13: Bacillus_HBL; PF04513.14: Baculo_PEP_C; PF06156.15: YabA; PF05478.13: Prominin; PF05531.14: NPV_P10; PF07889.14: DUF1664; PF10498.11: IFT57; - HyS0070.17 HyS0070.017 804 - sex-linked-abnormal - - - 57.4491 44.9383 40.3675 79.8544 127.078 107.53 53.934 46.4777 55.652325 117.304 50.20585 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: transmembrane protein 39A-like [Hydra vulgaris] 7.00E-151 XP_012562505.1 transmembrane protein 39A isoform 1 Mus musculus 275 87 3.14E-85 35.729 NP_001192215 Transmembrane protein 39A-B TMEM39B RNA binding NA integral component of membrane PF10271.11: Tmp39; - HyS0070.26 HyS0070.026 805 - sex-linked-abnormal - - - 36.7836 47.9691 53.7673 62.9024 128.058 126.599 56.2351 47.93 50.3556 127.3285 52.08255 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 vesicle transport protein SFT2A-like [Exaiptasia pallida] 1.20E-56 XP_020904051.1 vesicle transport protein SFT2B Homo sapiens 199 100 2.45E-65 59.375 NP_955376 T-box transcription factor TBX19 SFT2D2 DNA-binding transcription factor activity vesicle-mediated transport integral component of membrane PF04178.14: Got1; PF13273.8: DUF4064; PF01943.19: Polysacc_synt; PF17319.4: DUF5362; PF01312.21: Bac_export_2; PF04647.17: AgrB; - HyS0070.21 HyS0070.021 806 - sex-linked-abnormal - - - 23.6531 18.2294 19.1806 21.0002 103.982 90.9165 18.865 23.333 20.515825 97.44925 21.099 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: dehydrodolichyl diphosphate syntase complex subunit nus1-like [Hydra vulgaris] 6.80E-84 XP_004209456.2 dehydrodolichyl diphosphate synthase complex subunit nus1 Danio rerio 156 74 4.09E-45 37.198 NP_001002356 Nogo-B receptor NUS1 "transferase activity, transferring alkyl or aryl (other than methyl) groups" dolichol biosynthetic process dehydrodolichyl diphosphate synthase complex PF01255.21: Prenyltransf; - HyS0007.346 HyS0007.346 807 - - 4 yes - 50.9207 59.8737 82.1331 63.6277 118.048 102.963 16.1877 28.7853 64.1388 110.5055 22.4865 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 predicted protein [Nematostella vectensis] 2.70E-131 XP_001626379.1 "4-aminobutyrate aminotransferase, mitochondrial isoform 1 precursor " Homo sapiens 480 91 2.90E-165 48.59 NP_000654 "4-aminobutyrate aminotransferase, mitochondrial" ABAT 4-aminobutyrate transaminase activity gamma-aminobutyric acid metabolic process 4-aminobutyrate transaminase complex PF00202.23: Aminotran_3; - HyS0070.68 HyS0070.068 808 - sex-linked-abnormal - - - 1601.78 1671.16 1649.29 1182.59 328.426 445.16 178.317 254.378 1526.205 386.793 216.3475 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: gelsolin-like protein 1 [Hydra vulgaris] 4.50E-157 XP_012559373.1 hypothetical protein DDB_G0289327 Dictyostelium discoideum AX4 265 99 3.29E-85 41.598 XP_001134515 Actin regulatory protein CAP-G NA actin filament binding actin filament severing cytoskeleton PF00626.24: Gelsolin; PF05116.15: S6PP; - HyS0057.58 HyS0057.058 809 - - 4 yes - 43.0434 25.8534 30.3779 22.6902 247.637 192.302 26.7954 19.728 30.491225 219.9695 23.2617 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: synaptotagmin-10-like [Hydra vulgaris] 1.90E-51 XP_004209887.1 synaptotagmin-11 isoform X2 Mus musculus 56.2 32 2.16E-07 27.928 XP_006501413 NA NA NA NA NA PF00168.32: C2; - HyS0007.393 HyS0007.393 810 - - 4 yes - 467.964 286.216 335.591 536.43 343.11 354.9 136.273 128.147 406.55025 349.005 132.21 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: translocon-associated protein subunit beta-like [Hydra vulgaris] 1.10E-61 XP_012559920.1 translocon-associated protein subunit beta precursor Danio rerio 191 90 5.11E-61 53.012 NP_001001399 Translocon-associated protein subunit beta SSR2 chaperone binding in utero embryonic development endoplasmic reticulum PF05753.16: TRAP_beta; PF07705.13: CARDB; - HyS0057.84 HyS0057.084 811 - - 4 yes - 150.224 83.1957 109.807 164.55 357.291 332.682 96.5818 88.2265 126.944175 344.9865 92.40415 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 PREDICTED: uncharacterized protein LOC100213905 [Hydra vulgaris] 4.20E-130 XP_002159555.2 perilipin-5 isoform X1 Mus musculus 55.1 49 7.69E-07 25.439 XP_006524868 NA NA NA NA NA PF03036.18: Perilipin; PF01730.18: UreF; PF18323.3: CSN5_C; PF02027.19: RolB_RolC; PF14434.8: Imm6; - HyS0057.82 HyS0057.082 812 - - 4 yes - 1470.63 1006.44 982.994 1425.6 633.497 689.117 289.886 329.688 1221.416 661.307 309.787 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 peptidyl-prolyl cis-trans isomerase B-like [Stylophora pistillata] 8.80E-78 XP_022784097.1 peptidyl-prolyl cis-trans isomerase B precursor Homo sapiens 291 99 5.19E-100 70.352 NP_000933 Peptidyl-prolyl cis-trans isomerase B PPIB peptidyl-prolyl cis-trans isomerase activity protein peptidyl-prolyl isomerization endoplasmic reticulum chaperone complex PF00160.23: Pro_isomerase; - HyS0007.284 HyS0007.284 813 - - 4 yes - 12.4617 11.8519 0.743473 0 346.374 397.531 12.6666 0 6.26426825 371.9525 6.3333 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF07761.14: DUF1617; - HyS0070.67 HyS0070.067 814 - sex-linked-abnormal - - - 15.4196 1.95666 12.5048 3.93303 422.558 354.503 6.45579 0.292487 8.4535225 388.5305 3.3741385 1 1 1 0 0 1 0 0 0 1 1 0 0 1 0 0 0 0 PREDICTED: gelsolin-like protein 1 [Hydra vulgaris] 2.90E-148 XP_012559373.1 hypothetical protein DDB_G0289327 Dictyostelium discoideum AX4 259 99 5.09E-83 41.047 XP_001134515 Gelsolin NA actin filament binding actin filament severing cytoskeleton PF00626.24: Gelsolin; - HyS0057.15 HyS0057.015 815 - - 4 yes - 88.9395 46.2236 30.5547 39.4582 1713.92 1461.25 818.775 535.432 51.294 1587.585 677.1035 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 RecName: Full=G2/mitotic-specific cyclin-B 6.00E-128 P51987.1 G2/mitotic-specific cyclin-B1 isoform 1 Homo sapiens 298 74 4.18E-97 50.903 NP_114172 Histone-lysine N-methyltransferase NA cyclin-dependent protein serine/threonine kinase regulator activity cell cycle nucleus PF00134.25: Cyclin_N; PF02984.21: Cyclin_C; - HyS0007.280 HyS0007.280 816 - - 4 yes - 13.6968 9.64551 0.790231 1.11934 927.759 912.42 17.6029 1.37084 6.31297025 920.0895 9.48687 1 1 1 0 0 1 0 0 0 1 1 1 0 0 1 0 0 0 no hits - - no hits - - - - - - NA NA NA NA NA PF07761.14: DUF1617; PF19973.1: TCAD7; PF06963.14: FPN1; PF17723.3: RHH_8; PF00969.21: MHC_II_beta; - HyS3947.3 HyS3947.003 - - - - yes 20.0511 0 9.1464 19.5362 0 0.862564 23.7752 20.0885 12.183425 0.431282 21.93185 1 0 1 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 Coiled-coil domain-containing protein 112 [Hydra vulgaris] 5.00E-37 XP_047141959.1 coiled-coil domain-containing protein 112 Homo sapiens 99.4 88 8.00E-24 34.64 NP_001362826.1 NA NA NA NA NA - -